Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis

Nature Immunology

Volumn 17, Issue 3, 2016, Pages 277-285

  Wei, Jun ^a   Long, Lingyun ^a   Yang, Kai ^a   Guy, Cliff ^a   Shrestha, Sharad ^a   Chen, Zuojia ^b   Wu, Chuan ^b   Vogel, Peter ^a   Neale, Geoffrey ^a   Green, Douglas R ^a   Chi, Hongbo ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHAGY PROTEIN 5; AUTOPHAGY PROTEIN 7; CASPASE 3; GAMMA INTERFERON; HERMES ANTIGEN; INTERLEUKIN 17; L SELECTIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MYC PROTEIN; PROTEIN; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG; ATG5 PROTEIN, MOUSE; ATG7 PROTEIN, MOUSE; AUTOPHAGY RELATED PROTEIN 5; AUTOPHAGY RELATED PROTEIN 7; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MICROTUBULE ASSOCIATED PROTEIN; MULTIPROTEIN COMPLEX; MYC PROTEIN, MOUSE; TARGET OF RAPAMYCIN KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CD8+ T LYMPHOCYTE; CELL LINEAGE; CELL SURVIVAL; CONTROLLED STUDY; ENVIRONMENTAL FACTOR; ESSENTIAL GENE; FLOW CYTOMETRY; GENE EXPRESSION; GLYCOLYSIS; HOMEOSTASIS; INFLAMMATION; METABOLIC REGULATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; TRANSCRIPTION REGULATION; TUMOR ASSOCIATED LEUKOCYTE; TUMOR RESISTANCE; ADENOCARCINOMA; ADOPTIVE TRANSFER; ANIMAL; CANCER TRANSPLANTATION; COLON TUMOR; DNA METHYLATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; IMMUNOBLOTTING; IMMUNOLOGY; KNOCKOUT MOUSE; LYMPHOCYTE ACTIVATION; METABOLISM; REAL TIME POLYMERASE CHAIN REACTION; TUMOR CELL LINE; UPREGULATION;

ADENOCARCINOMA; ADOPTIVE TRANSFER; ANIMALS; APOPTOSIS; AUTOPHAGY; AUTOPHAGY-RELATED PROTEIN 5; AUTOPHAGY-RELATED PROTEIN 7; CELL LINE, TUMOR; COLONIC NEOPLASMS; DNA METHYLATION; FLOW CYTOMETRY; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GLYCOLYSIS; HOMEOSTASIS; IMMUNOBLOTTING; LYMPHOCYTE ACTIVATION; LYMPHOCYTES, TUMOR-INFILTRATING; MICE; MICE, KNOCKOUT; MICROTUBULE-ASSOCIATED PROTEINS; MULTIPROTEIN COMPLEXES; NEOPLASM TRANSPLANTATION; PROTO-ONCOGENE PROTEINS C-MYC; REAL-TIME POLYMERASE CHAIN REACTION; T-LYMPHOCYTES, REGULATORY; TOR SERINE-THREONINE KINASES; UP-REGULATION;

EID: 84955590563     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3365     Document Type: Article

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