-
1
-
-
84940461152
-
Parkinson’s disease and age: The obvious but largely unexplored link
-
[CrossRef][PubMed]
-
Abdullah, R.; Basak, I.; Patil, K.S.; Alves, G.; Larsen, J.P.; Møller, S.G. Parkinson’s disease and age: The obvious but largely unexplored link. Exp. Gerontol. 2015, 68, 33–38. [CrossRef][PubMed]
-
(2015)
Exp. Gerontol
, vol.68
, pp. 33-38
-
-
Abdullah, R.1
Basak, I.2
Patil, K.S.3
Alves, G.4
Larsen, J.P.5
Møller, S.G.6
-
2
-
-
84911423174
-
The prevalence of Parkinson’s disease: A systematic review and meta-analysis. Mov
-
[CrossRef] [PubMed]
-
Pringsheim, T.; Jette, N.; Frolkis, A.; Steeves, T.D.L. The prevalence of Parkinson’s disease: A systematic review and meta-analysis. Mov. Disord. 2014, 29, 1583–1590. [CrossRef] [PubMed]
-
(2014)
Disord
, vol.29
, pp. 1583-1590
-
-
Pringsheim, T.1
Jette, N.2
Frolkis, A.3
Steeves, T.D.L.4
-
3
-
-
84855972240
-
Neuropathology of sporadic Parkinson’s disease: Evaluation and changes of concepts
-
[CrossRef] [PubMed]
-
Jellinger, K.A. Neuropathology of sporadic Parkinson’s disease: Evaluation and changes of concepts. Mov. Disord. 2012, 27, 8–30. [CrossRef] [PubMed]
-
(2012)
Mov. Disord
, vol.27
, pp. 8-30
-
-
Jellinger, K.A.1
-
4
-
-
84898057951
-
Time to redefine
-
[CrossRef][PubMed]
-
Berg, D.; Postuma, R.B.; Bloem, B.; Chan, P.; Dubois, B.; Gasser, T.; Goetz, C.G.; Halliday, G.M.; Hardy, J.; Lang, A.E.; et al. Time to redefine PD? Introductory statement of the MDS task force on the definition of Parkinson’s disease. Mov. Disord. 2014, 29, 454–462. [CrossRef][PubMed]
-
(2014)
Disord
, vol.29
, pp. 454-462
-
-
Berg, D.1
Postuma, R.B.2
Bloem, B.3
Chan, P.4
Dubois, B.5
Gasser, T.6
Goetz, C.G.7
Halliday, G.M.8
Hardy, J.9
Lang, A.E.10
-
5
-
-
84904043213
-
Premotor and nonmotor features of Parkinson’s disease. Curr
-
[CrossRef] [PubMed]
-
Goldman, J.G.; Postuma, R. Premotor and nonmotor features of Parkinson’s disease. Curr. Opin. Neurol. 2014, 27, 434–441. [CrossRef] [PubMed]
-
(2014)
Opin. Neurol
, vol.27
, pp. 434-441
-
-
Goldman, J.G.1
Postuma, R.2
-
6
-
-
34247631275
-
Multiple hit hypotheses for dopamine neuron loss in Parkinson’s disease
-
[CrossRef] [PubMed]
-
Sulzer, D. Multiple hit hypotheses for dopamine neuron loss in Parkinson’s disease. Trends Neurosci. 2007, 30, 244–250. [CrossRef] [PubMed]
-
(2007)
Trends Neurosci
, vol.30
, pp. 244-250
-
-
Sulzer, D.1
-
7
-
-
84871921766
-
100 years of Lewy pathology
-
[CrossRef] [PubMed]
-
Goedert, M.; Spillantini, M.G.; del Tredici, K.; Braak, H. 100 years of Lewy pathology. Nat. Rev. Neurol. 2013, 9, 13–24. [CrossRef] [PubMed]
-
(2013)
Nat. Rev. Neurol
, vol.9
, pp. 13-24
-
-
Goedert, M.1
Spillantini, M.G.2
Del Tredici, K.3
Braak, H.4
-
8
-
-
0030882856
-
Goedert, M. α-synuclein in Lewy bodies
-
[CrossRef] [PubMed]
-
Spillantini, M.G.; Schmidt, M.L.; Lee, V.M.; Trojanowski, J.Q.; Jakes, R.; Goedert, M. α-synuclein in Lewy bodies. Nature 1997, 388, 839–840. [CrossRef] [PubMed]
-
(1997)
Nature
, vol.388
, pp. 839-840
-
-
Spillantini, M.G.1
Schmidt, M.L.2
Lee, V.M.3
Trojanowski, J.Q.4
Jakes, R.5
-
9
-
-
0037333666
-
Staging of brain pathology related to sporadic Parkinson’s disease. Neurobiol
-
[CrossRef]
-
Braak, H.; del Tredici, K.; Rüb, U.; de Vos, R.A.I.; Jansen Steur, E.N.H.; Braak, E. Staging of brain pathology related to sporadic Parkinson’s disease. Neurobiol. Aging 2003, 24, 197–211. [CrossRef]
-
(2003)
Aging
, vol.24
, pp. 197-211
-
-
Braak, H.1
Del Tredici, K.2
Rüb, U.3
de Vos, R.A.I.4
Jansen Steur, E.N.H.5
Braak, E.6
-
10
-
-
84857536339
-
Nigral pathology and parkinsonian signs in elders without Parkinson disease
-
[CrossRef] [PubMed]
-
Buchman, A.S.; Shulman, J.M.; Nag, S.; Leurgans, S.E.; Arnold, S.E.; Morris, M.C.; Schneider, J.A.; Bennett, D.A. Nigral pathology and parkinsonian signs in elders without Parkinson disease. Ann. Neurol. 2012, 71, 258–266. [CrossRef] [PubMed]
-
(2012)
Ann. Neurol
, vol.71
, pp. 258-266
-
-
Buchman, A.S.1
Shulman, J.M.2
Nag, S.3
Leurgans, S.E.4
Arnold, S.E.5
Morris, M.C.6
Schneider, J.A.7
Bennett, D.A.8
-
11
-
-
36749051047
-
Chronic microglial activation and progressive dopaminergic neurotoxicity
-
[CrossRef] [PubMed]
-
Block, M.L.; Hong, J.-S. Chronic microglial activation and progressive dopaminergic neurotoxicity. Biochem. Soc. Trans. 2007, 35, 1127–1132. [CrossRef] [PubMed]
-
(2007)
Biochem. Soc. Trans
, vol.35
, pp. 1127-1132
-
-
Block, M.L.1
Hong, J.-S.2
-
12
-
-
62549133546
-
Neuroinflammation in Parkinson’s disease: A target for neuroprotection?
-
[CrossRef]
-
Hirsch, E.C.; Hunot, S. Neuroinflammation in Parkinson’s disease: A target for neuroprotection? Lancet Neurol. 2009, 8, 382–397. [CrossRef]
-
(2009)
Lancet Neurol
, vol.8
, pp. 382-397
-
-
Hirsch, E.C.1
Hunot, S.2
-
13
-
-
0141741347
-
Parkinson’s disease: Mechanisms and models
-
[CrossRef]
-
Dauer, W.; Przedborski, S. Parkinson’s disease: Mechanisms and models. Neuron 2003, 39, 889–909. [CrossRef]
-
(2003)
Neuron
, vol.39
, pp. 889-909
-
-
Dauer, W.1
Przedborski, S.2
-
14
-
-
5544229693
-
Classic toxin-induced animal models of Parkinson’s disease: 6-OHDA and MPTP
-
[CrossRef] [PubMed]
-
Schober, A. Classic toxin-induced animal models of Parkinson’s disease: 6-OHDA and MPTP. Cell Tissue Res. 2004, 318, 215–224. [CrossRef] [PubMed]
-
(2004)
Cell Tissue Res
, vol.318
, pp. 215-224
-
-
Schober, A.1
-
15
-
-
0020680904
-
Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis
-
[CrossRef] [PubMed]
-
Langston, J.W.; Ballard, P.; Tetrud, J.W.; Irwin, I. Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis. Science 1983, 219, 979–980. [CrossRef] [PubMed]
-
(1983)
Science
, vol.219
, pp. 979-980
-
-
Langston, J.W.1
Ballard, P.2
Tetrud, J.W.3
Irwin, I.4
-
16
-
-
0035091767
-
The parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): A technical review of its utility and safety
-
[CrossRef] [PubMed]
-
Przedborski, S.; Jackson-Lewis, V.; Naini, A.B.; Jakowec, M.; Petzinger, G.; Miller, R.; Akram, M. The parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): A technical review of its utility and safety. J. Neurochem. 2001, 76, 1265–1274. [CrossRef] [PubMed]
-
(2001)
J. Neurochem
, vol.76
, pp. 1265-1274
-
-
Przedborski, S.1
Jackson-Lewis, V.2
Naini, A.B.3
Jakowec, M.4
Petzinger, G.5
Miller, R.6
Akram, M.7
-
17
-
-
0021810979
-
Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine
-
[CrossRef]
-
Nicklas, W.; Vyas, I.; Heikkila, R.E. Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine. Life Sci. 1985, 36, 2503–2508. [CrossRef]
-
(1985)
Life Sci
, vol.36
, pp. 2503-2508
-
-
Nicklas, W.1
Vyas, I.2
Heikkila, R.E.3
-
18
-
-
0023093745
-
MPP+ and mitochondrial function
-
[CrossRef]
-
Nicklas, W.J.; Youngster, S.K.; Kindt, M.V.; Heikkila, R.E. MPTP, MPP+ and mitochondrial function. Life Sci. 1987, 40, 721–729. [CrossRef]
-
(1987)
Life Sci
, vol.40
, pp. 721-729
-
-
Nicklas, W.J.1
Youngster, S.K.2
Kindt, M.V.3
Heikkila, R.4
-
19
-
-
0001485756
-
MPTP: A review of its mechanisms of neurotoxicity
-
[CrossRef]
-
Przedborski, S.; Vila, M. MPTP: A review of its mechanisms of neurotoxicity. Clin. Neurosci. Res. 2001, 1, 407–418. [CrossRef]
-
(2001)
Clin. Neurosci. Res
, vol.1
, pp. 407-418
-
-
Przedborski, S.1
Vila, M.2
-
20
-
-
0000340348
-
Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: Uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity
-
[CrossRef] [PubMed]
-
Javitch, J.A.; D’Amato, R.J.; Strittmatter, S.M.; Snyder, S.H. Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: Uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity. Proc. Natl. Acad. Sci. USA 1985, 82, 2173–2177. [CrossRef] [PubMed]
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 2173-2177
-
-
Javitch, J.A.1
D’Amato, R.J.2
Strittmatter, S.M.3
Snyder, S.H.4
-
21
-
-
0021680307
-
Uptake of MPP+ by dopamine neurons explains selectivity of parkinsonism-inducing neurotoxin, MPTP
-
[CrossRef]
-
Javitch, J.A.; Snyder, S.H. Uptake of MPP+ by dopamine neurons explains selectivity of parkinsonism-inducing neurotoxin, MPTP. Eur. J. Pharmacol. 1984, 106, 455–456. [CrossRef]
-
(1984)
Eur. J. Pharmacol
, vol.106
, pp. 455-456
-
-
Javitch, J.A.1
Snyder, S.H.2
-
22
-
-
0022447043
-
Prevention of the nigrostriatal toxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by inhibitors of 3,4-dihydroxyphenylethylamine transport
-
[CrossRef] [PubMed]
-
Mayer, R.A.; Kindt, M.V.; Heikkila, R.E. Prevention of the nigrostriatal toxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by inhibitors of 3,4-dihydroxyphenylethylamine transport. J. Neurochem. 1986, 47, 1073–1079. [CrossRef] [PubMed]
-
(1986)
J. Neurochem
, vol.47
, pp. 1073-1079
-
-
Mayer, R.A.1
Kindt, M.V.2
Heikkila, R.E.3
-
23
-
-
0027160147
-
Uptake into synaptic dopamine vesicles: Possible involvement in MPTP neurotoxicity
-
[CrossRef] [PubMed]
-
Del Zompo, M.; Piccardi, M.P.; Ruiu, S.; Quartu, M.; Gessa, G.L.; Vaccari, A. Selective MPP+ uptake into synaptic dopamine vesicles: Possible involvement in MPTP neurotoxicity. Br. J. Pharmacol. 1993, 109, 411–414. [CrossRef] [PubMed]
-
(1993)
Br. J. Pharmacol
, vol.109
, pp. 411-414
-
-
Del Zompo, M.1
Piccardi, M.P.2
Ruiu, S.3
Quartu, M.4
Gessa, G.L.5
Vaccari, A.6
-
24
-
-
0027260872
-
Redox cycling of MPP+: Evidence for a new mechanism involving hydride transfer with xanthine oxidase, aldehyde dehydrogenase, and lipoamide dehydrogenase
-
[CrossRef]
-
Klaidman, L.K.; Adams, J.D., Jr.; Leung, A.C.; Sam Kim, S.; Cadenas, E. Redox cycling of MPP+: Evidence for a new mechanism involving hydride transfer with xanthine oxidase, aldehyde dehydrogenase, and lipoamide dehydrogenase. Free Radic. Biol. Med. 1993, 15, 169–179. [CrossRef]
-
(1993)
Free Radic. Biol. Med
, vol.15
, pp. 169-179
-
-
Klaidman, L.K.1
Adams, J.D.2
Leung, A.C.3
Sam Kim, S.4
Cadenas, E.5
-
25
-
-
0023186383
-
Saitoh, T. Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 1-methyl-4-phenylpyridinium ion on activities of the enzymes in the electron transport system in mouse brain
-
[CrossRef] [PubMed]
-
Mizuno, Y.; Sone, N.; Saitoh, T. Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 1-methyl-4-phenylpyridinium ion on activities of the enzymes in the electron transport system in mouse brain. J. Neurochem. 1987, 48, 1787–1793. [CrossRef] [PubMed]
-
(1987)
J. Neurochem
, vol.48
, pp. 1787-1793
-
-
Mizuno, Y.1
Sone, N.2
-
26
-
-
0024207463
-
1-Methyl-4-phenyl- 1,2,3,6-tetrahydropyridine (MPTP) and free radicals in vitro. Biochem
-
[CrossRef]
-
Rossetti, Z.L.; Sotgiu, A.; Sharp, D.E.; Hadjiconstantinou, M.; Neff, N.H. 1-Methyl-4-phenyl- 1,2,3,6-tetrahydropyridine (MPTP) and free radicals in vitro. Biochem. Pharmacol. 1988, 37, 4573–4574. [CrossRef]
-
(1988)
Pharmacol
, vol.37
, pp. 4573-4574
-
-
Rossetti, Z.L.1
Sotgiu, A.2
Sharp, D.E.3
Hadjiconstantinou, M.4
Neff, N.H.5
-
27
-
-
0024997609
-
1-Methyl-4-phenylpyridinium (MPP+) induces NADH-dependent superoxide formation and enhances NADH-dependent lipid peroxidation in bovine heart submitochondrial particles
-
[CrossRef]
-
Hasegawa, E.; Takeshige, K.; Oishi, T.; Murai, Y.; Minakami, S. 1-Methyl-4-phenylpyridinium (MPP+) induces NADH-dependent superoxide formation and enhances NADH-dependent lipid peroxidation in bovine heart submitochondrial particles. Biochem. Biophys. Res. Commun. 1990, 170, 1049–1055. [CrossRef]
-
(1990)
Biochem. Biophys. Res. Commun
, vol.170
, pp. 1049-1055
-
-
Hasegawa, E.1
Takeshige, K.2
Oishi, T.3
Murai, Y.4
Minakami, S.5
-
28
-
-
0021154320
-
Repeated administration of N-methyl-4-phenyl 1,2,5,6-tetrahydropyridine to rats is not toxic to striatal dopamine neurones
-
[CrossRef]
-
Boyce, S.; Kelly, E.; Reavill, C.; Jenner, P.; Marsden, C.D. Repeated administration of N-methyl-4-phenyl 1,2,5,6-tetrahydropyridine to rats is not toxic to striatal dopamine neurones. Biochem. Pharmacol. 1984, 33, 1747–1752. [CrossRef]
-
(1984)
Biochem. Pharmacol
, vol.33
, pp. 1747-1752
-
-
Boyce, S.1
Kelly, E.2
Reavill, C.3
Jenner, P.4
Marsden, C.D.5
-
29
-
-
0021339035
-
Neurochemical and behavioral effects of systemic and intranigral administration of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the rat
-
[CrossRef]
-
Chiueh, C.C.; Markey, S.P.; Burns, R.S.; Johannessen, J.N.; Pert, A.; Kopin, I.J. Neurochemical and behavioral effects of systemic and intranigral administration of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the rat. Eur. J. Pharmacol. 1984, 100, 189–194. [CrossRef]
-
(1984)
Eur. J. Pharmacol
, vol.100
, pp. 189-194
-
-
Chiueh, C.C.1
Markey, S.P.2
Burns, R.S.3
Johannessen, J.N.4
Pert, A.5
Kopin, I.J.6
-
30
-
-
0033749345
-
Susceptibility in the mouse: Behavioral, neurochemical, and histological analysis of gender and strain differences
-
[CrossRef] [PubMed]
-
Sedelis, M.; Hofele, K.; Auburger, G.W.; Morgan, S.; Huston, J.P.; Schwarting, R.K. MPTP susceptibility in the mouse: Behavioral, neurochemical, and histological analysis of gender and strain differences. Behav. Genet. 2000, 30, 171–182. [CrossRef] [PubMed]
-
(2000)
Behav. Genet
, vol.30
, pp. 171-182
-
-
Sedelis, M.1
Hofele, K.2
Auburger, G.W.3
Morgan, S.4
Huston, J.P.5
Schwarting, R.6
-
31
-
-
0034615837
-
Evidence for resistance to MPTP in C57BL/6 x BALB/c F1 hybrids as compared with their progenitor strains
-
[CrossRef] [PubMed]
-
Sedelis, M.; Hofele, K.; Auburger, G.W.; Morgan, S.; Huston, J.P.; Schwarting, R.K. Evidence for resistance to MPTP in C57BL/6 x BALB/c F1 hybrids as compared with their progenitor strains. Neuroreport 2000, 11, 1093–1096. [CrossRef] [PubMed]
-
(2000)
Neuroreport
, vol.11
, pp. 1093-1096
-
-
Sedelis, M.1
Hofele, K.2
Auburger, G.W.3
Morgan, S.4
Huston, J.P.5
Schwarting, R.K.6
-
32
-
-
0035214256
-
Neurochemical findings in the MPTP model of Parkinson’s disease
-
[CrossRef] [PubMed]
-
Schmidt, N.; Ferger, B. Neurochemical findings in the MPTP model of Parkinson’s disease. J. Neural Transm. 2001, 108, 1263–1282. [CrossRef] [PubMed]
-
(2001)
J. Neural Transm
, vol.108
, pp. 1263-1282
-
-
Schmidt, N.1
Ferger, B.2
-
33
-
-
0028784523
-
Time course and morphology of dopaminergic neuronal death caused by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
-
[CrossRef]
-
Jackson-Lewis, V.; Jakowec, M.; Burke, R.E.; Przedborski, S. Time course and morphology of dopaminergic neuronal death caused by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Neurodegener. J. Neurodegener. Disord. Neuroprot. Neuroregener. 1995, 4, 257–269. [CrossRef]
-
(1995)
Neurodegener. J. Neurodegener. Disord. Neuroprot. Neuroregener
, vol.4
, pp. 257-269
-
-
Jackson-Lewis, V.1
Jakowec, M.2
Burke, R.E.3
Przedborski, S.4
-
34
-
-
0030888286
-
In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining
-
[CrossRef]
-
Tatton, N.A.; Kish, S.J. In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining. Neuroscience 1997, 77, 1037–1048. [CrossRef]
-
(1997)
Neuroscience
, vol.77
, pp. 1037-1048
-
-
Tatton, N.A.1
Kish, S.J.2
-
35
-
-
0033966487
-
_-Synuclein up-regulation in substantia nigra dopaminergic neurons following administration of the parkinsonian toxin MPTP
-
[CrossRef] [PubMed]
-
Vila, M.; Vukosavic, S.; Jackson-Lewis, V.; Neystat, M.; Jakowec, M.; Przedborski, S. _-Synuclein up-regulation in substantia nigra dopaminergic neurons following administration of the parkinsonian toxin MPTP. J. Neurochem. 2000, 74, 721–729. [CrossRef] [PubMed]
-
(2000)
J. Neurochem
, vol.74
, pp. 721-729
-
-
Vila, M.1
Vukosavic, S.2
Jackson-Lewis, V.3
Neystat, M.4
Jakowec, M.5
Przedborski, S.6
-
36
-
-
0030984413
-
A chronic MPTP model reproducing the slow evolution of Parkinson’s disease
-
[CrossRef]
-
Bezard, E.; Imbert, C.; Deloire, X.; Bioulac, B.; Gross, C.E. A chronic MPTP model reproducing the slow evolution of Parkinson’s disease: Evolution of motor symptoms in the monkey. Brain Res. 1997, 766, 107–112. [CrossRef]
-
(1997)
Evolution of Motor Symptoms in the Monkey. Brain Res
, vol.766
, pp. 107-112
-
-
Bezard, E.1
Imbert, C.2
Deloire, X.3
Bioulac, B.4
Gross, C.E.5
-
37
-
-
47349104402
-
Glial reactions in Parkinson’s disease. Mov
-
[CrossRef] [PubMed]
-
McGeer, P.L.; McGeer, E.G. Glial reactions in Parkinson’s disease. Mov. Disord. 2008, 23, 474–483. [CrossRef] [PubMed]
-
(2008)
Disord
, vol.23
, pp. 474-483
-
-
McGeer, P.L.1
McGeer, E.G.2
-
38
-
-
84958106930
-
Differential roles of M1 and M2 microglia in neurodegenerative diseases
-
[CrossRef] [PubMed]
-
Tang, Y.; Le, W. Differential roles of M1 and M2 microglia in neurodegenerative diseases. Mol. Neurobiol. 2015, 1–14. [CrossRef] [PubMed]
-
(2015)
Mol. Neurobiol
, pp. 1-14
-
-
Tang, Y.1
Le, W.2
-
39
-
-
0032100191
-
Microglial and astrocytic involvement in a murine model of Parkinson’s disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)
-
[CrossRef]
-
Kohutnicka, M.; Lewandowska, E.; Kurkowska-Jastrzebska, I.; Członkowski, A.; Członkowska, A. Microglial and astrocytic involvement in a murine model of Parkinson’s disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Immunopharmacology 1998, 39, 167–180. [CrossRef]
-
(1998)
Immunopharmacology
, vol.39
, pp. 167-180
-
-
Kohutnicka, M.1
Lewandowska, E.2
Kurkowska-Jastrzebska, I.3
Członkowski, A.4
Członkowska, A.5
-
40
-
-
0030175757
-
Microglial reaction in MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) induced Parkinson’s disease mice model
-
[CrossRef] [PubMed]
-
Członkowska, A.; Kohutnicka, M.; Kurkowska-Jastrzebska, I.; Członkowski, A. Microglial reaction in MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) induced Parkinson’s disease mice model. Neurodegeneration 1996, 5, 137–143. [CrossRef] [PubMed]
-
(1996)
Neurodegeneration
, vol.5
, pp. 137-143
-
-
Członkowska, A.1
Kohutnicka, M.2
Kurkowska-Jastrzebska, I.3
Członkowski, A.4
-
41
-
-
0036522967
-
Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease
-
[PubMed]
-
Wu, D.C.; Jackson-Lewis, V.; Vila, M.; Tieu, K.; Teismann, P.; Vadseth, C.; Choi, D.-K.; Ischiropoulos, H.; Przedborski, S. Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease. J. Neurosci. 2002, 22, 1763–1771. [PubMed]
-
(2002)
J. Neurosci
, vol.22
, pp. 1763-1771
-
-
Wu, D.C.1
Jackson-Lewis, V.2
Vila, M.3
Tieu, K.4
Teismann, P.5
Vadseth, C.6
Choi, D.-K.7
Ischiropoulos, H.8
Przedborski, S.9
-
42
-
-
0038317693
-
Dynamics of expression of the mRNA for cytokines and inducible nitric synthase in a murine model of the Parkinson’s disease
-
Ciesielska, A.; Joniec, I.; Przybyłkowski, A.; Gromadzka, G.; Kurkowska-Jastrzebska, I.; Członkowska, A.; Członkowski, A. Dynamics of expression of the mRNA for cytokines and inducible nitric synthase in a murine model of the Parkinson’s disease. Acta Neurobiol. Exp. 2003, 63, 117–126.
-
(2003)
Acta Neurobiol. Exp
, vol.63
, pp. 117-126
-
-
Ciesielska, A.1
Joniec, I.2
Przybyłkowski, A.3
Gromadzka, G.4
Kurkowska-Jastrzebska, I.5
Członkowska, A.6
Członkowski, A.7
-
43
-
-
67649506219
-
Neurotransmitters and inflammation in three regimens of the MPTP mouse model of Parkinson’s disease
-
[CrossRef] [PubMed]
-
Luchtman, D.W.; Shao, D.; Song, C. Behavior, neurotransmitters and inflammation in three regimens of the MPTP mouse model of Parkinson’s disease. Physiol. Behav. 2009, 98, 130–138. [CrossRef] [PubMed]
-
(2009)
Physiol. Behav
, vol.98
, pp. 130-138
-
-
Luchtman, D.W.1
Shao, D.2
Song, C.B.3
-
44
-
-
77957744015
-
MPTP-induced neuroinflammation increases the expression of pro-inflammatory cytokines and their receptors in mouse brain
-
[CrossRef] [PubMed]
-
Lofrumento, D.D.; Saponaro, C.; Cianciulli, A.; de Nuccio, F.; Mitolo, V.; Nicolardi, G.; Panaro, M.A. MPTP-induced neuroinflammation increases the expression of pro-inflammatory cytokines and their receptors in mouse brain. Neuroimmunomodulation 2011, 18, 79–88. [CrossRef] [PubMed]
-
(2011)
Neuroimmunomodulation
, vol.18
, pp. 79-88
-
-
Lofrumento, D.D.1
Saponaro, C.2
Cianciulli, A.3
de Nuccio, F.4
Mitolo, V.5
Nicolardi, G.6
Panaro, M.A.7
-
45
-
-
54349089328
-
The effects of MPTP on the activation of microglia/astrocytes and cytokine/chemokine levels in different mice strains
-
[CrossRef] [PubMed]
-
Yasuda, Y.; Shimoda, T.; Uno, K.; Tateishi, N.; Furuya, S.; Yagi, K.; Suzuki, K.; Fujita, S. The effects of MPTP on the activation of microglia/astrocytes and cytokine/chemokine levels in different mice strains. J. Neuroimmunol. 2008, 204, 43–51. [CrossRef] [PubMed]
-
(2008)
J. Neuroimmunol
, vol.204
, pp. 43-51
-
-
Yasuda, Y.1
Shimoda, T.2
Uno, K.3
Tateishi, N.4
Furuya, S.5
Yagi, K.6
Suzuki, K.7
Fujita, S.8
-
46
-
-
33847681800
-
Temporal mRNA profiles of inflammatory mediators in the murine 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrimidine model of Parkinson’s disease
-
[CrossRef] [PubMed]
-
Pattarini, R.; Smeyne, R.J.; Morgan, J.I. Temporal mRNA profiles of inflammatory mediators in the murine 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrimidine model of Parkinson’s disease. Neuroscience 2007, 145, 654–668. [CrossRef] [PubMed]
-
(2007)
Neuroscience
, vol.145
, pp. 654-668
-
-
Pattarini, R.1
Smeyne, R.J.2
Morgan, J.I.3
-
47
-
-
33847101490
-
Long-lasting reactive changes observed in microglia in the striatal and substantia nigral of mice after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
-
[CrossRef] [PubMed]
-
Yasuda, Y.; Shinagawa, R.; Yamada, M.; Mori, T.; Tateishi, N.; Fujita, S. Long-lasting reactive changes observed in microglia in the striatal and substantia nigral of mice after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Brain Res. 2007, 1138, 196–202. [CrossRef] [PubMed]
-
(2007)
Brain Res
, vol.1138
, pp. 196-202
-
-
Yasuda, Y.1
Shinagawa, R.2
Yamada, M.3
Mori, T.4
Tateishi, N.5
Fujita, S.6
-
48
-
-
84869154969
-
ROCK/Cdc42-mediated microglial motility and gliapse formation lead to phagocytosis of degenerating dopaminergic neurons in vivo
-
[CrossRef] [PubMed]
-
Barcia, C.; Ros, C.M.; Annese, V.; Carrillo-de Sauvage, M.A.; Ros-Bernal, F.; Gómez, A.; Yuste, J.E.; Campuzano, C.M.; de Pablos, V.; Fernandez-Villalba, E.; Herrero, M.T. ROCK/Cdc42-mediated microglial motility and gliapse formation lead to phagocytosis of degenerating dopaminergic neurons in vivo. Sci. Rep. 2012, 2, 809. [CrossRef] [PubMed]
-
(2012)
Sci. Rep
, vol.2
, pp. 809
-
-
Barcia, C.1
Ros, C.M.2
Annese, V.3
Carrillo-De Sauvage, M.A.4
Ros-Bernal, F.5
Gómez, A.6
Yuste, J.E.7
Campuzano, C.M.8
de Pablos, V.9
Fernandez-Villalba, E.10
Herrero, M.T.11
-
49
-
-
0344528794
-
The inflammatory reaction following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine intoxication in mouse
-
[CrossRef] [PubMed]
-
Kurkowska-Jastrzebska, I.; Wrónska, A.; Kohutnicka, M.; Członkowski, A.; Członkowska, A. The inflammatory reaction following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine intoxication in mouse. Exp. Neurol. 1999, 156, 50–61. [CrossRef] [PubMed]
-
(1999)
Exp. Neurol
, vol.156
, pp. 50-61
-
-
Kurkowska-Jastrzebska, I.1
Wrónska, A.2
Kohutnicka, M.3
Członkowski, A.4
Członkowska, A.5
-
50
-
-
58849107919
-
Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease
-
[CrossRef] [PubMed]
-
Brochard, V.; Combadière, B.; Prigent, A.; Laouar, Y.; Perrin, A.; Beray-Berthat, V.; Bonduelle, O.; Alvarez-Fischer, D.; Callebert, J.; Launay, J.-M.; et al. Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease. J. Clin. Investig. 2009, 119, 182–192. [CrossRef] [PubMed]
-
(2009)
J. Clin. Investig
, vol.119
, pp. 182-192
-
-
Brochard, V.1
Combadière, B.2
Prigent, A.3
Laouar, Y.4
Perrin, A.5
Beray-Berthat, V.6
Bonduelle, O.7
Alvarez-Fischer, D.8
Callebert, J.9
Launay, J.-M.10
-
51
-
-
36249032567
-
Neuroprotective activities of CD4+CD25+ regulatory T cells in an animal model of Parkinson’s disease
-
[CrossRef] [PubMed]
-
Reynolds, A.D.; Banerjee, R.; Liu, J.; Gendelman, H.E.; Mosley, R.L. Neuroprotective activities of CD4+CD25+ regulatory T cells in an animal model of Parkinson’s disease. J. Leukoc. Biol. 2007, 82, 1083–1094. [CrossRef] [PubMed]
-
(2007)
J. Leukoc. Biol
, vol.82
, pp. 1083-1094
-
-
Reynolds, A.D.1
Banerjee, R.2
Liu, J.3
Gendelman, H.E.4
Mosley, R.L.5
-
52
-
-
0035408611
-
Cytokines: Past, present, and future
-
[CrossRef] [PubMed]
-
Oppenheim, J.J. Cytokines: Past, present, and future. Int. J. Hematol. 2001, 74, 3–8. [CrossRef] [PubMed]
-
(2001)
Int. J. Hematol
, vol.74
, pp. 3-8
-
-
Oppenheim, J.J.1
-
53
-
-
36248974200
-
Historical review of cytokines
-
[CrossRef] [PubMed]
-
Dinarello, C.A. Historical review of cytokines. Eur. J. Immunol. 2007, 37, S34–S45. [CrossRef] [PubMed]
-
(2007)
Eur. J. Immunol
, vol.37
, pp. S34-S45
-
-
Dinarello, C.A.1
-
54
-
-
34547099363
-
The interferons: 50 years after their discovery, there is much more to learn
-
[CrossRef] [PubMed]
-
Pestka, S. The interferons: 50 years after their discovery, there is much more to learn. J. Biol. Chem. 2007, 282, 20047–20051. [CrossRef] [PubMed]
-
(2007)
J. Biol. Chem
, vol.282
, pp. 20047-20051
-
-
Pestka, S.1
-
55
-
-
84892497397
-
Interferons in the central nervous system
-
[CrossRef] [PubMed]
-
Owens, T.; Khorooshi, R.; Wlodarczyk, A.; Asgari, N. Interferons in the central nervous system: A few instruments play many tunes. Glia 2014, 62, 339–355. [CrossRef] [PubMed]
-
(2014)
A Few Instruments Play Many Tunes. Glia
, vol.62
, pp. 339-355
-
-
Owens, T.1
Khorooshi, R.2
Wlodarczyk, A.3
Asgari, N.4
-
56
-
-
33947515418
-
Involvement of interferon- in microglial-mediated loss of dopaminergic neurons
-
[CrossRef] [PubMed]
-
Mount, M.P.; Lira, A.; Grimes, D.; Smith, P.D.; Faucher, S.; Slack, R.; Anisman, H.; Hayley, S.; Park, D.S. Involvement of interferon- in microglial-mediated loss of dopaminergic neurons. J. Neurosci. 2007, 27, 3328–3337. [CrossRef] [PubMed]
-
(2007)
J. Neurosci
, vol.27
, pp. 3328-3337
-
-
Mount, M.P.1
Lira, A.2
Grimes, D.3
Smith, P.D.4
Faucher, S.5
Slack, R.6
Anisman, H.7
Hayley, S.8
Park, D.S.9
-
57
-
-
79959977446
-
IFN- signaling, with the synergistic contribution of TNF-γ, mediates cell specific microglial and astroglial activation in experimental models of Parkinson’s disease
-
[CrossRef] [PubMed]
-
Barcia, C.; Ros, C.M.; Annese, V.; Gómez, A.; Ros-Bernal, F.; Aguado-Llera, D.; Martínez-Pagán, M.E.; de Pablos, V.; Fernandez-Villalba, E.; Herrero, M.T. IFN- signaling, with the synergistic contribution of TNF-γ, mediates cell specific microglial and astroglial activation in experimental models of Parkinson’s disease. Cell Death Dis. 2012, 3, e142. [CrossRef] [PubMed]
-
(2012)
Cell Death Dis
, vol.3
-
-
Barcia, C.1
Ros, C.M.2
Annese, V.3
Gómez, A.4
Ros-Bernal, F.5
Aguado-Llera, D.6
Martínez-Pagán, M.E.7
de Pablos, V.8
Fernandez-Villalba, E.9
Herrero, M.T.10
-
58
-
-
84867617885
-
The soluble isoform of CX3CL1 is necessary for neuroprotection in a mouse model of Parkinson’s disease
-
[CrossRef] [PubMed]
-
Morganti, J.M.; Nash, K.R.; Grimmig, B.A.; Ranjit, S.; Small, B.; Bickford, P.C.; Gemma, C. The soluble isoform of CX3CL1 is necessary for neuroprotection in a mouse model of Parkinson’s disease. J. Neurosci. 2012, 32, 14592–14601. [CrossRef] [PubMed]
-
(2012)
J. Neurosci
, vol.32
, pp. 14592-14601
-
-
Morganti, J.M.1
Nash, K.R.2
Grimmig, B.A.3
Ranjit, S.4
Small, B.5
Bickford, P.C.6
Gemma, C.7
-
59
-
-
33745573660
-
Control of microglial neurotoxicity by the fractalkine receptor
-
[CrossRef] [PubMed]
-
Cardona, A.E.; Pioro, E.P.; Sasse, M.E.; Kostenko, V.; Cardona, S.M.; Dijkstra, I.M.; Huang, D.; Kidd, G.; Dombrowski, S.; Dutta, R.; et al. Control of microglial neurotoxicity by the fractalkine receptor. Nat. Neurosci. 2006, 9, 917–924. [CrossRef] [PubMed]
-
(2006)
Nat. Neurosci
, vol.9
, pp. 917-924
-
-
Cardona, A.E.1
Pioro, E.P.2
Sasse, M.E.3
Kostenko, V.4
Cardona, S.M.5
Dijkstra, I.M.6
Huang, D.7
Kidd, G.8
Dombrowski, S.9
Dutta, R.10
-
60
-
-
33845980539
-
Chemokines in the MPTP model of Parkinson’s disease: Absence of CCL2 and its receptor CCR2 does not protect against striatal neurodegeneration
-
[CrossRef] [PubMed]
-
Kalkonde, Y.V.; Morgan, W.W.; Sigala, J.; Maffi, S.K.; Condello, C.; Kuziel, W.; Ahuja, S.S.; Ahuja, S.K. Chemokines in the MPTP model of Parkinson’s disease: Absence of CCL2 and its receptor CCR2 does not protect against striatal neurodegeneration. Brain Res. 2007, 1128, 1–11. [CrossRef] [PubMed]
-
(2007)
Brain Res
, vol.1128
, pp. 1-11
-
-
Kalkonde, Y.V.1
Morgan, W.W.2
Sigala, J.3
Maffi, S.K.4
Condello, C.5
Kuziel, W.6
Ahuja, S.S.7
Ahuja, S.K.8
-
61
-
-
84866540147
-
Lack of CCR5 modifies glial phenotypes and population of the nigral dopaminergic neurons, but not MPTP-induced dopaminergic neurodegeneration. Neurobiol
-
[CrossRef] [PubMed]
-
Choi, D.-Y.; Lee, M.K.; Hong, J.T. Lack of CCR5 modifies glial phenotypes and population of the nigral dopaminergic neurons, but not MPTP-induced dopaminergic neurodegeneration. Neurobiol. Dis. 2013, 49, 159–168. [CrossRef] [PubMed]
-
(2013)
Dis
, vol.49
, pp. 159-168
-
-
Choi, D.-Y.1
Lee, M.K.2
Hong, J.T.3
-
62
-
-
18944378145
-
A role of IL-1 in MPTP-induced changes in striatal dopaminergic and serotoninergic transporter binding: Clues from interleukin-1 type I receptor-deficient mice
-
[CrossRef] [PubMed]
-
Hébert, G.; Mingam, R.; Arsaut, J.; Dantzer, R.; Demotes-Mainard, J. A role of IL-1 in MPTP-induced changes in striatal dopaminergic and serotoninergic transporter binding: Clues from interleukin-1 type I receptor-deficient mice. Mol. Brain Res. 2005, 136, 267–270. [CrossRef] [PubMed]
-
(2005)
Mol. Brain Res
, vol.136
, pp. 267-270
-
-
Hébert, G.1
Mingam, R.2
Arsaut, J.3
Dantzer, R.4
Demotes-Mainard, J.5
-
63
-
-
0036789082
-
Increased vulnerability of dopaminergic neurons in MPTP-lesioned interleukin-6 deficient mice
-
[CrossRef] [PubMed]
-
Bolin, L.M.; Strycharska-Orczyk, I.; Murray, R.; Langston, J.W.; di Monte, D. Increased vulnerability of dopaminergic neurons in MPTP-lesioned interleukin-6 deficient mice. J. Neurochem. 2002, 83, 167–175. [CrossRef] [PubMed]
-
(2002)
J. Neurochem
, vol.83
, pp. 167-175
-
-
Bolin, L.M.1
Strycharska-Orczyk, I.2
Murray, R.3
Langston, J.W.4
Di Monte, D.5
-
64
-
-
0142090539
-
Compromised reactive microgliosis in MPTP-lesioned IL-6 KO mice
-
[CrossRef]
-
Cardenas, H.; Bolin, L.M. Compromised reactive microgliosis in MPTP-lesioned IL-6 KO mice. Brain Res. 2003, 985, 89–97. [CrossRef]
-
(2003)
Brain Res
, vol.985
, pp. 89-97
-
-
Cardenas, H.1
Bolin, L.M.2
-
65
-
-
38549102077
-
TNF-mediated inflammatory disease
-
[CrossRef] [PubMed]
-
Bradley, J.R. TNF-mediated inflammatory disease. J. Pathol. 2008, 214, 149–160. [CrossRef] [PubMed]
-
(2008)
J. Pathol
, vol.214
, pp. 149-160
-
-
Bradley, J.R.1
-
66
-
-
2542475349
-
Genetic ablation of tumor necrosis factor-
-
[CrossRef] [PubMed]
-
Ferger, B.; Leng, A.; Mura, A.; Hengerer, B.; Feldon, J. Genetic ablation of tumor necrosis factor-α (TNF-α) and pharmacological inhibition of TNF-synthesis attenuates MPTP toxicity in mouse striatum. J. Neurochem. 2004, 89, 822–833. [CrossRef] [PubMed]
-
(2004)
J. Neurochem
, vol.89
, pp. 822-833
-
-
Ferger, B.1
Leng, A.2
Mura, A.3
Hengerer, B.4
Feldon, J.5
-
67
-
-
33947323582
-
TNF-
-
[CrossRef] [PubMed]
-
Zhao, C.; Ling, Z.; Newman, M.B.; Bhatia, A.; Carvey, P.M. TNF-α knockout and minocycline treatment attenuates blood brain barrier leakage in MPTP-treated mice. Neurobiol. Dis. 2007, 26, 36–46. [CrossRef] [PubMed]
-
(2007)
Neurobiol. Dis
, vol.26
, pp. 36-46
-
-
Zhao, C.1
Ling, Z.2
Newman, M.B.3
Bhatia, A.4
Carvey, P.M.5
-
68
-
-
0036719568
-
Mice deficient in TNF receptors are protected against dopaminergic neurotoxicity
-
[CrossRef] [PubMed]
-
Sriram, K.; Matheson, J.M.; Benkovic, S.A.; Miller, D.B.; Luster, M.I.; O’Callaghan, J.P. Mice deficient in TNF receptors are protected against dopaminergic neurotoxicity: Implications for Parkinson’s disease. FASEB J. 2002, 16, 1474–1476. [CrossRef] [PubMed]
-
(2002)
Implications for Parkinson’s Disease. FASEB J
, vol.16
, pp. 1474-1476
-
-
Sriram, K.1
Matheson, J.M.2
Benkovic, S.A.3
Miller, D.B.4
Luster, M.I.5
O’Callaghan, J.P.6
-
69
-
-
33646255922
-
O’Callaghan, J.P. Deficiency of TNF receptors suppresses microglial activation and alters the susceptibility of brain regions to MPTP-induced neurotoxicity: Role of TNF-α
-
[CrossRef] [PubMed]
-
Sriram, K.; Matheson, J.M.; Benkovic, S.A.; Miller, D.B.; Luster, M.I.; O’Callaghan, J.P. Deficiency of TNF receptors suppresses microglial activation and alters the susceptibility of brain regions to MPTP-induced neurotoxicity: Role of TNF-α. FASEB J. 2006, 20, 670–682. [CrossRef] [PubMed]
-
(2006)
FASEB J
, vol.20
, pp. 670-682
-
-
Sriram, K.1
Matheson, J.M.2
Benkovic, S.A.3
Miller, D.B.4
Luster, M.I.5
-
70
-
-
0036432917
-
Role of TNF-
-
[CrossRef] [PubMed]
-
Rousselet, E.; Callebert, J.; Parain, K.; Joubert, C.; Hunot, S.; Hartmann, A.; Jacque, C.; Perez-Diaz, F.; Cohen-Salmon, C.; Launay, J.-M.; et al. Role of TNF-α Receptors in Mice Intoxicated with the Parkinsonian Toxin MPTP. Exp. Neurol. 2002, 177, 183–192. [CrossRef] [PubMed]
-
(2002)
Neurol
, vol.177
, pp. 183-192
-
-
Rousselet, E.1
Callebert, J.2
Parain, K.3
Joubert, C.4
Hunot, S.5
Hartmann, A.6
Jacque, C.7
Perez-Diaz, F.8
Cohen-Salmon, C.9
Launay, J.-M.10
-
71
-
-
12744265234
-
Tumor necrosis factor-α receptor ablation in a chronic MPTP mouse model of Parkinson’s disease
-
[CrossRef] [PubMed]
-
Leng, A.; Mura, A.; Feldon, J.; Ferger, B. Tumor necrosis factor-α receptor ablation in a chronic MPTP mouse model of Parkinson’s disease. Neurosci. Lett. 2005, 375, 107–111. [CrossRef] [PubMed]
-
(2005)
Neurosci. Lett
, vol.375
, pp. 107-111
-
-
Leng, A.1
Mura, A.2
Feldon, J.3
Ferger, B.4
-
72
-
-
84892795119
-
Inflammasomes in the CNS. Nat
-
[CrossRef] [PubMed]
-
Walsh, J.G.; Muruve, D.A.; Power, C. Inflammasomes in the CNS. Nat. Rev. Neurosci. 2014, 15, 84–97. [CrossRef] [PubMed]
-
(2014)
Rev. Neurosci
, vol.15
, pp. 84-97
-
-
Walsh, J.G.1
Muruve, D.A.2
Power, C.3
-
73
-
-
0036671894
-
The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-β. Mol
-
[CrossRef]
-
Martinon, F.; Burns, K.; Tschopp, J. The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-β. Mol. Cell 2002, 10, 417–426. [CrossRef]
-
(2002)
Cell
, vol.10
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
74
-
-
77950362382
-
The inflammasomes
-
[CrossRef] [PubMed]
-
Schroder, K.; Tschopp, J. The inflammasomes. Cell 2010, 140, 821–832. [CrossRef] [PubMed]
-
(2010)
Cell
, vol.140
, pp. 821-832
-
-
Schroder, K.1
Tschopp, J.2
-
75
-
-
84869504451
-
Inflammasomes and their roles in health and disease. Annu
-
[CrossRef] [PubMed]
-
Lamkanfi, M.; Dixit, V.M. Inflammasomes and their roles in health and disease. Annu. Rev. Cell Dev. Biol. 2012, 28, 137–161. [CrossRef] [PubMed]
-
(2012)
Rev. Cell Dev. Biol
, vol.28
, pp. 137-161
-
-
Lamkanfi, M.1
Dixit, V.M.2
-
76
-
-
77649177009
-
Interleukin 18 in the CNS
-
[CrossRef] [PubMed]
-
Alboni, S.; Cervia, D.; Sugama, S.; Conti, B. Interleukin 18 in the CNS. J. Neuroinflamm. 2010, 7, 9. [CrossRef] [PubMed]
-
(2010)
J. Neuroinflamm
, vol.7
, pp. 9
-
-
Alboni, S.1
Cervia, D.2
Sugama, S.3
Conti, B.4
-
77
-
-
23444441962
-
Interleukin-1 and neuronal injury
-
[CrossRef] [PubMed]
-
Allan, S.M.; Tyrrell, P.J.; Rothwell, N.J. Interleukin-1 and neuronal injury. Nat. Rev. Immunol. 2005, 5, 629–640. [CrossRef] [PubMed]
-
(2005)
Nat. Rev. Immunol
, vol.5
, pp. 629-640
-
-
Allan, S.M.1
Tyrrell, P.J.2
Rothwell, N.J.3
-
78
-
-
0033601995
-
Transgenic mice expressing a dominant negative mutant interleukin-1β converting enzyme show resistance to MPTP neurotoxicity
-
[CrossRef] [PubMed]
-
Klevenyi, P.; Andreassen, O.; Ferrante, R.J.; Schleicher, J.R.; Friedlander, R.M.; Beal, M.F. Transgenic mice expressing a dominant negative mutant interleukin-1β converting enzyme show resistance to MPTP neurotoxicity. Neuroreport 1999, 10, 635–638. [CrossRef] [PubMed]
-
(1999)
Neuroreport
, vol.10
, pp. 635-638
-
-
Klevenyi, P.1
Andreassen, O.2
Ferrante, R.J.3
Schleicher, J.R.4
Friedlander, R.M.5
Beal, M.F.6
-
79
-
-
84873123076
-
Triggering of inflammasome by aggregated α-synuclein, an inflammatory response in synucleinopathies
-
[CrossRef] [PubMed]
-
Codolo, G.; Plotegher, N.; Pozzobon, T.; Brucale, M.; Tessari, I.; Bubacco, L.; de Bernard, M. Triggering of inflammasome by aggregated α-synuclein, an inflammatory response in synucleinopathies. PLoS ONE 2013, 8, e55375. [CrossRef] [PubMed]
-
(2013)
Plos ONE
, vol.8
-
-
Codolo, G.1
Plotegher, N.2
Pozzobon, T.3
Brucale, M.4
Tessari, I.5
Bubacco, L.6
de Bernard, M.7
-
80
-
-
84938301985
-
NLRP3 inflammasome is expressed and functional in mouse brain microglia but not in astrocytes
-
[CrossRef] [PubMed]
-
Gustin, A.; Kirchmeyer, M.; Koncina, E.; Felten, P.; Losciuto, S.; Heurtaux, T.; Tardivel, A.; Heuschling, P.; Dostert, C. NLRP3 inflammasome is expressed and functional in mouse brain microglia but not in astrocytes. PLoS ONE 2015, 10, e0130624. [CrossRef] [PubMed]
-
(2015)
Plos ONE
, vol.10
-
-
Gustin, A.1
Kirchmeyer, M.2
Koncina, E.3
Felten, P.4
Losciuto, S.5
Heurtaux, T.6
Tardivel, A.7
Heuschling, P.8
Dostert, C.9
-
81
-
-
84920990887
-
Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome
-
[CrossRef] [PubMed]
-
Yan, Y.; Jiang, W.; Liu, L.; Wang, X.; Ding, C.; Tian, Z.; Zhou, R. Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome. Cell 2015, 160, 62–73. [CrossRef] [PubMed]
-
(2015)
Cell
, vol.160
, pp. 62-73
-
-
Yan, Y.1
Jiang, W.2
Liu, L.3
Wang, X.4
Ding, C.5
Tian, Z.6
Zhou, R.7
-
82
-
-
84888062088
-
Metabolic inflammation exacerbates dopaminergic neuronal degeneration in response to acute MPTP challenge in type 2 diabetes mice
-
[CrossRef] [PubMed]
-
Wang, L.; Zhai, Y.-Q.; Xu, L.-L.; Qiao, C.; Sun, X.-L.; Ding, J.-H.; Lu, M.; Hu, G. Metabolic inflammation exacerbates dopaminergic neuronal degeneration in response to acute MPTP challenge in type 2 diabetes mice. Exp. Neurol. 2014, 251, 22–29. [CrossRef] [PubMed]
-
(2014)
Exp. Neurol
, vol.251
, pp. 22-29
-
-
Wang, L.1
Zhai, Y.-Q.2
Xu, L.-L.3
Qiao, C.4
Sun, X.-L.5
Ding, J.-H.6
Lu, M.7
Hu, G.8
-
83
-
-
34447328426
-
Neuroinflammation in Parkinson’s patients and MPTP-treated mice is not restricted to the nigrostriatal system: Microgliosis and differential expression of interleukin-1 receptors in the olfactory bulb
-
[CrossRef] [PubMed]
-
Vroon, A.; Drukarch, B.; Bol, J.G.J.M.; Cras, P.; Brevé, J.J.P.; Allan, S.M.; Relton, J.K.; Hoogland, P.V.J.M.; van Dam, A.-M. Neuroinflammation in Parkinson’s patients and MPTP-treated mice is not restricted to the nigrostriatal system: Microgliosis and differential expression of interleukin-1 receptors in the olfactory bulb. Exp. Gerontol. 2007, 42, 762–771. [CrossRef] [PubMed]
-
(2007)
Exp. Gerontol
, vol.42
, pp. 762-771
-
-
Vroon, A.1
Drukarch, B.2
Bol, J.G.J.M.3
Cras, P.4
Brevé, J.J.P.5
Allan, S.M.6
Relton, J.K.7
Hoogland, P.V.J.M.8
van Dam, A.-M.9
-
84
-
-
4444333135
-
Interleukin-18 null mice show diminished microglial activation and reduced dopaminergic neuron loss following acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment
-
[CrossRef] [PubMed]
-
Sugama, S.; Wirz, S.A.; Barr, A.M.; Conti, B.; Bartfai, T.; Shibasaki, T. Interleukin-18 null mice show diminished microglial activation and reduced dopaminergic neuron loss following acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment. Neuroscience 2004, 128, 451–458. [CrossRef] [PubMed]
-
(2004)
Neuroscience
, vol.128
, pp. 451-458
-
-
Sugama, S.1
Wirz, S.A.2
Barr, A.M.3
Conti, B.4
Bartfai, T.5
Shibasaki, T.6
-
85
-
-
79551611535
-
Repairing the parkinsonian brain with neurotrophic factors
-
[CrossRef] [PubMed]
-
Aron, L.; Klein, R. Repairing the parkinsonian brain with neurotrophic factors. Trends Neurosci. 2011, 34, 88–100. [CrossRef] [PubMed]
-
(2011)
Trends Neurosci
, vol.34
, pp. 88-100
-
-
Aron, L.1
Klein, R.2
-
86
-
-
84908615939
-
Neurotrophic factors: From neurodevelopmental regulators to novel therapies for Parkinson’s disease
-
[PubMed]
-
Hegarty, S.V.; O’Keeffe, G.W.; Sullivan, A.M. Neurotrophic factors: From neurodevelopmental regulators to novel therapies for Parkinson’s disease. Neural Regen. Res. 2014, 9, 1708–1711. [PubMed]
-
(2014)
Neural Regen. Res
, vol.9
, pp. 1708-1711
-
-
Hegarty, S.V.1
O’Keeffe, G.W.2
Sullivan, A.M.3
-
87
-
-
84877350585
-
Current advances in using neurotrophic factors to treat neurodegenerative disorders
-
[CrossRef] [PubMed]
-
Weissmiller, A.M.; Wu, C. Current advances in using neurotrophic factors to treat neurodegenerative disorders. Transl. Neurodegener. 2012, 1, 14. [CrossRef] [PubMed]
-
(2012)
Transl. Neurodegener
, vol.1
, pp. 14
-
-
Weissmiller, A.M.1
Wu, C.2
-
88
-
-
0025876757
-
BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra
-
[CrossRef] [PubMed]
-
Hyman, C.; Hofer, M.; Barde, Y.A.; Juhasz, M.; Yancopoulos, G.D.; Squinto, S.P.; Lindsay, R.M. BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra. Nature 1991, 350, 230–232. [CrossRef] [PubMed]
-
(1991)
Nature
, vol.350
, pp. 230-232
-
-
Hyman, C.1
Hofer, M.2
Barde, Y.A.3
Juhasz, M.4
Yancopoulos, G.D.5
Squinto, S.P.6
Lindsay, R.M.7
-
89
-
-
84859879356
-
The neurotrophin family of neurotrophic factors: An overview. Methods Mol. Biol
-
Skaper, S.D. The neurotrophin family of neurotrophic factors: An overview. Methods Mol. Biol. Clifton NJ 2012, 846, 1–12.
-
(2012)
Clifton NJ
, vol.846
, pp. 1-12
-
-
Skaper, S.D.1
-
90
-
-
2942642117
-
Identification of brain-derived neurotrophic factor in nestin-expressing astroglial cells in the neostriatum of 1-methyl-4-phenyl- 1,2,3,6-tetrahydropyridine-treated mice
-
[CrossRef] [PubMed]
-
Chen, L.-W.; Hu, H.-J.; Liu, H.-L.; Yung, K.K.L.; Chan, Y.S. Identification of brain-derived neurotrophic factor in nestin-expressing astroglial cells in the neostriatum of 1-methyl-4-phenyl- 1,2,3,6-tetrahydropyridine-treated mice. Neuroscience 2004, 126, 941–953. [CrossRef] [PubMed]
-
(2004)
Neuroscience
, vol.126
, pp. 941-953
-
-
Chen, L.-W.1
Hu, H.-J.2
Liu, H.-L.3
Yung, K.K.L.4
Chan, Y.S.5
-
91
-
-
84865092868
-
Exercise does not protect against MPTP-induced neurotoxicity in BDNF haploinsufficient mice
-
[CrossRef] [PubMed]
-
Gerecke, K.M.; Jiao, Y.; Pagala, V.; Smeyne, R.J. Exercise does not protect against MPTP-induced neurotoxicity in BDNF haploinsufficient mice. PLoS ONE 2012, 7, e43250. [CrossRef] [PubMed]
-
(2012)
Plos ONE
, vol.7
-
-
Gerecke, K.M.1
Jiao, Y.2
Pagala, V.3
Smeyne, R.J.4
-
92
-
-
79851511400
-
Chronic deprivation of TrkB signaling leads to selective late-onset nigrostriatal dopaminergic degeneration. Exp
-
[CrossRef] [PubMed]
-
Baydyuk, M.; Nguyen, M.T.; Xu, B. Chronic deprivation of TrkB signaling leads to selective late-onset nigrostriatal dopaminergic degeneration. Exp. Neurol. 2011, 228, 118–125. [CrossRef] [PubMed]
-
(2011)
Neurol
, vol.228
, pp. 118-125
-
-
Baydyuk, M.1
Nguyen, M.T.2
Xu, B.3
-
93
-
-
0026681597
-
Ventricular injection of nerve growth factor increases dopamine content in the striata of MPTP-treated mice. Neurochem
-
[CrossRef] [PubMed]
-
Garcia, E.; Rios, C.; Sotelo, J. Ventricular injection of nerve growth factor increases dopamine content in the striata of MPTP-treated mice. Neurochem. Res. 1992, 17, 979–982. [CrossRef] [PubMed]
-
(1992)
Res
, vol.17
, pp. 979-982
-
-
Garcia, E.1
Rios, C.2
Sotelo, J.3
-
94
-
-
33745883258
-
Localization of nerve growth factor, neurotrophin-3, and glial cell line-derived neurotrophic factor in nestin-expressing reactive astrocytes in the caudate-putamen of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated C57/Bl mice
-
[CrossRef] [PubMed]
-
Chen, L.-W.; Zhang, J.-P.; Kwok-Yan Shum, D.; Chan, Y.-S. Localization of nerve growth factor, neurotrophin-3, and glial cell line-derived neurotrophic factor in nestin-expressing reactive astrocytes in the caudate-putamen of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated C57/Bl mice. J. Comp. Neurol. 2006, 497, 898–909. [CrossRef] [PubMed]
-
(2006)
J. Comp. Neurol
, vol.497
, pp. 898-909
-
-
Chen, L.-W.1
Zhang, J.-P.2
Kwok-Yan Shum, D.3
Chan, Y.-S.4
-
95
-
-
84863356004
-
Neurorestoration. Parkinsonism Relat
-
[CrossRef]
-
Airavaara, M.; Voutilainen, M.H.; Wang, Y.; Hoffer, B. Neurorestoration. Parkinsonism Relat. Disord. 2012, 18, S143–S146. [CrossRef]
-
(2012)
Disord
, vol.18
, pp. S143-S146
-
-
Airavaara, M.1
Voutilainen, M.H.2
Wang, Y.3
Hoffer, B.4
-
96
-
-
0027285510
-
GDNF: A glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons
-
[CrossRef] [PubMed]
-
Lin, L.F.; Doherty, D.H.; Lile, J.D.; Bektesh, S.; Collins, F. GDNF: A glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science 1993, 260, 1130–1132. [CrossRef] [PubMed]
-
(1993)
Science
, vol.260
, pp. 1130-1132
-
-
Lin, L.F.1
Doherty, D.H.2
Lile, J.D.3
Bektesh, S.4
Collins, F.5
-
97
-
-
0005934486
-
Neurotrophic factors in neurodegenerative disorders: Model of Parkinson’s disease. Neurotox
-
[CrossRef] [PubMed]
-
Garcia de Yebenes, J.; Yebenes, J.; Mena, M.A. Neurotrophic factors in neurodegenerative disorders: Model of Parkinson’s disease. Neurotox. Res. 2000, 2, 115–137. [CrossRef] [PubMed]
-
(2000)
Res
, vol.2
, pp. 115-137
-
-
Garcia De Yebenes, J.1
Yebenes, J.2
Mena, M.A.3
-
98
-
-
0034192597
-
Glial cell line-derived neurotrophic factor is essential for postnatal survival of midbrain dopamine neurons
-
[PubMed]
-
Granholm, A.C.; Reyland, M.; Albeck, D.; Sanders, L.; Gerhardt, G.; Hoernig, G.; Shen, L.; Westphal, H.; Hoffer, B. Glial cell line-derived neurotrophic factor is essential for postnatal survival of midbrain dopamine neurons. J. Neurosci. 2000, 20, 3182–3190. [PubMed]
-
(2000)
J. Neurosci
, vol.20
, pp. 3182-3190
-
-
Granholm, A.C.1
Reyland, M.2
Albeck, D.3
Sanders, L.4
Gerhardt, G.5
Hoernig, G.6
Shen, L.7
Westphal, H.8
Hoffer, B.9
-
99
-
-
0032514206
-
GDNF administration induces recovery of the nigrostriatal dopaminergic system both in young and aged parkinsonian mice
-
[CrossRef] [PubMed]
-
Date, I.; Aoi, M.; Tomita, S.; Collins, F.; Ohmoto, T. GDNF administration induces recovery of the nigrostriatal dopaminergic system both in young and aged parkinsonian mice. Neuroreport 1998, 9, 2365–2369. [CrossRef] [PubMed]
-
(1998)
Neuroreport
, vol.9
, pp. 2365-2369
-
-
Date, I.1
Aoi, M.2
Tomita, S.3
Collins, F.4
Ohmoto, T.5
-
100
-
-
0028834063
-
Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo
-
[CrossRef] [PubMed]
-
Tomac, A.; Lindqvist, E.; Lin, L.F.; Ogren, S.O.; Young, D.; Hoffer, B.J.; Olson, L. Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo. Nature 1995, 373, 335–339. [CrossRef] [PubMed]
-
(1995)
Nature
, vol.373
, pp. 335-339
-
-
Tomac, A.1
Lindqvist, E.2
Lin, L.F.3
Ogren, S.O.4
Young, D.5
Hoffer, B.J.6
Olson, L.7
-
101
-
-
0032563356
-
Glial cell line-derived neurotrophic factor protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotoxicity in C57BL/6 mice
-
[CrossRef]
-
Cheng, F.C.; Ni, D.R.; Wu, M.C.; Kuo, J.S.; Chia, L.G. Glial cell line-derived neurotrophic factor protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotoxicity in C57BL/6 mice. Neurosci. Lett. 1998, 252, 87–90. [CrossRef]
-
(1998)
Neurosci. Lett
, vol.252
, pp. 87-90
-
-
Cheng, F.C.1
Ni, D.R.2
Wu, M.C.3
Kuo, J.S.4
Chia, L.G.5
-
102
-
-
33846294812
-
GDNF applied to the MPTP-lesioned nigrostriatal system requires TGF-
-
[CrossRef] [PubMed]
-
Schober, A.; Peterziel, H.; von Bartheld, C.S.; Simon, H.; Krieglstein, K.; Unsicker, K. GDNF applied to the MPTP-lesioned nigrostriatal system requires TGF-β for its neuroprotective action. Neurobiol. Dis. 2007, 25, 378–391. [CrossRef] [PubMed]
-
(2007)
Neurobiol. Dis
, vol.25
, pp. 378-391
-
-
Schober, A.1
Peterziel, H.2
Von Bartheld, C.S.3
Simon, H.4
Krieglstein, K.5
Unsicker, K.6
-
103
-
-
77955171756
-
Macrophage-mediated GDNF delivery protects against dopaminergic neurodegeneration: A therapeutic strategy for Parkinson’s disease
-
[CrossRef] [PubMed]
-
Biju, K.C.; Zhou, Q.; Li, G.; Imam, S.Z.; Roberts, J.L.; Morgan, W.W.; Clark, R.A.; Li, S. Macrophage-mediated GDNF delivery protects against dopaminergic neurodegeneration: A therapeutic strategy for Parkinson’s disease. Mol. Ther. J. Am. Soc. Gene Ther. 2010, 18, 1536–1544. [CrossRef] [PubMed]
-
(2010)
Mol. Ther. J. Am. Soc. Gene Ther
, vol.18
, pp. 1536-1544
-
-
Biju, K.C.1
Zhou, Q.2
Li, G.3
Imam, S.Z.4
Roberts, J.L.5
Morgan, W.W.6
Clark, R.A.7
Li, S.8
-
104
-
-
84873256816
-
Bone marrow-derived microglia-based neurturin delivery protects against dopaminergic neurodegeneration in a mouse model of Parkinson’s disease. Neurosci
-
[CrossRef] [PubMed]
-
Biju, K.C.; Santacruz, R.A.; Chen, C.; Zhou, Q.; Yao, J.; Rohrabaugh, S.L.; Clark, R.A.; Roberts, J.L.; Phillips, K.A.; Imam, S.Z.; et al. Bone marrow-derived microglia-based neurturin delivery protects against dopaminergic neurodegeneration in a mouse model of Parkinson’s disease. Neurosci. Lett. 2013, 535, 24–29. [CrossRef] [PubMed]
-
(2013)
Lett
, vol.535
, pp. 24-29
-
-
Biju, K.C.1
Santacruz, R.A.2
Chen, C.3
Zhou, Q.4
Yao, J.5
Rohrabaugh, S.L.6
Clark, R.A.7
Roberts, J.L.8
Phillips, K.A.9
Imam, S.Z.10
-
105
-
-
38049112581
-
Signaling does not modulate MPTP toxicity but is required for regeneration of dopaminergic axon terminals
-
[CrossRef] [PubMed]
-
Kowsky, S.; Pöppelmeyer, C.; Kramer, E.R.; Falkenburger, B.H.; Kruse, A.; Klein, R.; Schulz, J.B. RET signaling does not modulate MPTP toxicity but is required for regeneration of dopaminergic axon terminals. Proc. Natl. Acad. Sci. USA 2007, 104, 20049–20054. [CrossRef] [PubMed]
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 20049-20054
-
-
Kowsky, S.1
Pöppelmeyer, C.2
Kramer, E.R.3
Falkenburger, B.H.4
Kruse, A.5
Klein, R.6
Schulz, J.7
-
106
-
-
55549097410
-
Differential effects of the dopamine neurotoxin MPTP in animals with a partial deletion of the GDNF receptor, GFR α1, gene
-
[CrossRef] [PubMed]
-
Boger, H.A.; Middaugh, L.D.; Zaman, V.; Hoffer, B.; Granholm, A.-C. Differential effects of the dopamine neurotoxin MPTP in animals with a partial deletion of the GDNF receptor, GFR α1, gene. Brain Res. 2008, 1241, 18–28. [CrossRef] [PubMed]
-
(2008)
Brain Res
, vol.1241
, pp. 18-28
-
-
Boger, H.A.1
Middaugh, L.D.2
Zaman, V.3
Hoffer, B.4
Granholm, A.-C.5
-
107
-
-
0029414747
-
Development of mesencephalic dopaminergic neurons and the transforming growth factor-β superfamily
-
[PubMed]
-
Krieglstein, K.; Suter-Crazzolara, C.; Unsicker, K. Development of mesencephalic dopaminergic neurons and the transforming growth factor-β superfamily. J. Neural Transm. Suppl. 1995, 46, 209–216. [PubMed]
-
(1995)
J. Neural Transm. Suppl
, vol.46
, pp. 209-216
-
-
Krieglstein, K.1
Suter-Crazzolara, C.2
Unsicker, K.3
-
108
-
-
0032403377
-
Glial cell line-derived neurotrophic factor requires transforming growth factor-β for exerting its full neurotrophic potential on peripheral and CNS neurons
-
[PubMed]
-
Krieglstein, K.; Henheik, P.; Farkas, L.; Jaszai, J.; Galter, D.; Krohn, K.; Unsicker, K. Glial cell line-derived neurotrophic factor requires transforming growth factor-β for exerting its full neurotrophic potential on peripheral and CNS neurons. J. Neurosci. 1998, 18, 9822–9834. [PubMed]
-
(1998)
J. Neurosci
, vol.18
, pp. 9822-9834
-
-
Krieglstein, K.1
Henheik, P.2
Farkas, L.3
Jaszai, J.4
Galter, D.5
Krohn, K.6
Unsicker, K.7
-
109
-
-
0033559397
-
Glial cell line-derived neurotrophic factor rescues target-deprived sympathetic spinal cord neurons but requires transforming growth factor- β as cofactor in vivo
-
[PubMed]
-
Schober, A.; Hertel, R.; Arumäe, U.; Farkas, L.; Jaszai, J.; Krieglstein, K.; Saarma, M.; Unsicker, K. Glial cell line-derived neurotrophic factor rescues target-deprived sympathetic spinal cord neurons but requires transforming growth factor- β as cofactor in vivo. J. Neurosci. 1999, 19, 2008–2015. [PubMed]
-
(1999)
J. Neurosci
, vol.19
, pp. 2008-2015
-
-
Schober, A.1
Hertel, R.2
Arumäe, U.3
Farkas, L.4
Jaszai, J.5
Krieglstein, K.6
Saarma, M.7
Unsicker, K.8
-
110
-
-
33244470664
-
Transforming growth factor β2 haploinsufficient mice develop age-related nigrostriatal dopamine deficits. Neurobiol
-
[CrossRef] [PubMed]
-
Andrews, Z.B.; Zhao, H.; Frugier, T.; Meguro, R.; Grattan, D.R.; Koishi, K.; McLennan, I.S. Transforming growth factor β2 haploinsufficient mice develop age-related nigrostriatal dopamine deficits. Neurobiol. Dis. 2006, 21, 568–575. [CrossRef] [PubMed]
-
(2006)
Dis
, vol.21
, pp. 568-575
-
-
Andrews, Z.B.1
Zhao, H.2
Frugier, T.3
Meguro, R.4
Grattan, D.R.5
Koishi, K.6
McLennan, I.S.7
-
111
-
-
0041659303
-
Transforming growth factor β1 overexpression in the nigrostriatal system increases the dopaminergic deficit of MPTP mice
-
[CrossRef]
-
Sánchez-Capelo, A.; Colin, P.; Guibert, B.; Biguet, N.F.; Mallet, J. Transforming growth factor β1 overexpression in the nigrostriatal system increases the dopaminergic deficit of MPTP mice. Mol. Cell. Neurosci. 2003, 23, 614–625. [CrossRef]
-
(2003)
Mol. Cell. Neurosci
, vol.23
, pp. 614-625
-
-
Sánchez-Capelo, A.1
Colin, P.2
Guibert, B.3
Biguet, N.F.4
Mallet, J.5
-
112
-
-
0025880072
-
Epidermal growth factor enhances striatal dopaminergic parameters in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mouse
-
[CrossRef] [PubMed]
-
Hadjiconstantinou, M.; Fitkin, J.G.; Dalia, A.; Neff, N.H. Epidermal growth factor enhances striatal dopaminergic parameters in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mouse. J. Neurochem. 1991, 57, 479–482. [CrossRef] [PubMed]
-
(1991)
J. Neurochem
, vol.57
, pp. 479-482
-
-
Hadjiconstantinou, M.1
Fitkin, J.G.2
Dalia, A.3
Neff, N.H.4
-
113
-
-
0025034302
-
MPTP-treated young mice but not aging mice show partial recovery of the nigrostriatal dopaminergic system by stereotaxic injection of acidic fibroblast growth factor (AFGF)
-
[CrossRef]
-
Date, I.; Notter, M.F.; Felten, S.Y.; Felten, D.L. MPTP-treated young mice but not aging mice show partial recovery of the nigrostriatal dopaminergic system by stereotaxic injection of acidic fibroblast growth factor (aFGF). Brain Res. 1990, 526, 156–160. [CrossRef]
-
(1990)
Brain Res
, vol.526
, pp. 156-160
-
-
Date, I.1
Notter, M.F.2
Felten, S.Y.3
Felten, D.L.4
-
114
-
-
0025440265
-
Basic FGF reverses chemical and morphological deficits in the nigrostriatal system of MPTP-treated mice
-
[PubMed]
-
Otto, D.; Unsicker, K. Basic FGF reverses chemical and morphological deficits in the nigrostriatal system of MPTP-treated mice. J. Neurosci. 1990, 10, 1912–1921. [PubMed]
-
(1990)
J. Neurosci
, vol.10
, pp. 1912-1921
-
-
Otto, D.1
Unsicker, K.2
-
115
-
-
0027740184
-
Protective actions of human recombinant basic fibroblast growth factor on MPTP-lesioned nigrostriatal dopamine neurons after intraventricular infusion
-
[CrossRef] [PubMed]
-
Chadi, G.; Møller, A.; Rosén, L.; Janson, A.M.; Agnati, L.A.; Goldstein, M.; Ogren, S.O.; Pettersson, R.F.; Fuxe, K. Protective actions of human recombinant basic fibroblast growth factor on MPTP-lesioned nigrostriatal dopamine neurons after intraventricular infusion. Exp. Brain Res. 1993, 97, 145–158. [CrossRef] [PubMed]
-
(1993)
Exp. Brain Res
, vol.97
, pp. 145-158
-
-
Chadi, G.1
Møller, A.2
Rosén, L.3
Janson, A.M.4
Agnati, L.A.5
Goldstein, M.6
Ogren, S.O.7
Pettersson, R.F.8
Fuxe, K.9
-
116
-
-
0027326161
-
FGF-2 modulates dopamine and dopamine-related striatal transmitter systems in the intact and MPTP-lesioned mouse
-
[CrossRef] [PubMed]
-
Otto, D.; Unsicker, K. FGF-2 modulates dopamine and dopamine-related striatal transmitter systems in the intact and MPTP-lesioned mouse. Eur. J. Neurosci. 1993, 5, 927–932. [CrossRef] [PubMed]
-
(1993)
Eur. J. Neurosci
, vol.5
, pp. 927-932
-
-
Otto, D.1
Unsicker, K.2
-
117
-
-
0028430953
-
FGF-2 in the MPTP model of Parkinson’s disease
-
Unsicker, K. FGF-2 in the MPTP model of Parkinson’s disease: Effects on astroglial cells. Glia 1994, 11, 47–56.
-
(1994)
Effects on Astroglial Cells. Glia
, vol.11
, pp. 47-56
-
-
Unsicker, K.1
-
118
-
-
0029924692
-
Early effects of FGF-2 on glial cells in the MPTP-lesioned striatum
-
[CrossRef] [PubMed]
-
Wirth, S.B.; Rufer, M.; Unsicker, K. Early effects of FGF-2 on glial cells in the MPTP-lesioned striatum. Exp. Neurol. 1996, 137, 191–200. [CrossRef] [PubMed]
-
(1996)
Exp. Neurol
, vol.137
, pp. 191-200
-
-
Wirth, S.B.1
Rufer, M.2
Unsicker, K.3
-
119
-
-
33645109173
-
Von Bohlen und Halbach, O. FGF-2 deficiency does not alter vulnerability of the dopaminergic nigrostriatal system towards MPTP intoxication in mice
-
[CrossRef] [PubMed]
-
Zechel, S.; Jarosik, J.; Kiprianova, I.; Schober, A.; Unsicker, K.; von Bohlen und Halbach, O. FGF-2 deficiency does not alter vulnerability of the dopaminergic nigrostriatal system towards MPTP intoxication in mice. Eur. J. Neurosci. 2006, 23, 1671–1675. [CrossRef] [PubMed]
-
(2006)
Eur. J. Neurosci
, vol.23
, pp. 1671-1675
-
-
Zechel, S.1
Jarosik, J.2
Kiprianova, I.3
Schober, A.4
Unsicker, K.5
-
120
-
-
28844432459
-
The insulin-like growth factor system and its pleiotropic functions in brain
-
[CrossRef] [PubMed]
-
Russo, V.C.; Gluckman, P.D.; Feldman, E.L.; Werther, G.A. The insulin-like growth factor system and its pleiotropic functions in brain. Endocr. Rev. 2005, 26, 916–943. [CrossRef] [PubMed]
-
(2005)
Endocr. Rev
, vol.26
, pp. 916-943
-
-
Russo, V.C.1
Gluckman, P.D.2
Feldman, E.L.3
Werther, G.A.4
-
121
-
-
70349849852
-
IGF-1 signaling reduces neuro-inflammatory response and sensitivity of neurons to MPTP
-
[CrossRef] [PubMed]
-
Nadjar, A.; Berton, O.; Guo, S.; Leneuve, P.; Dovero, S.; Diguet, E.; Tison, F.; Zhao, B.; Holzenberger, M.; Bezard, E. IGF-1 signaling reduces neuro-inflammatory response and sensitivity of neurons to MPTP. Neurobiol. Aging 2009, 30, 2021–2030. [CrossRef] [PubMed]
-
(2009)
Neurobiol. Aging
, vol.30
, pp. 2021-2030
-
-
Nadjar, A.1
Berton, O.2
Guo, S.3
Leneuve, P.4
Dovero, S.5
Diguet, E.6
Tison, F.7
Zhao, B.8
Holzenberger, M.9
Bezard, E.10
-
122
-
-
79958213139
-
Restorative effects of platelet derived growth factor-BB in rodent models of Parkinson’s disease
-
[PubMed]
-
Zachrisson, O.; Zhao, M.; Andersson, A.; Dannaeus, K.; Häggblad, J.; Isacson, R.; Nielsen, E.; Patrone, C.; Rönnholm, H.; Wikstrom, L.; et al. Restorative effects of platelet derived growth factor-BB in rodent models of Parkinson’s disease. J. Parkinsons Dis. 2011, 1, 49–63. [PubMed]
-
(2011)
J. Parkinsons Dis
, vol.1
, pp. 49-63
-
-
Zachrisson, O.1
Zhao, M.2
Andersson, A.3
Dannaeus, K.4
Häggblad, J.5
Isacson, R.6
Nielsen, E.7
Patrone, C.8
Rönnholm, H.9
Wikstrom, L.10
-
123
-
-
0027082893
-
Platelet-derived growth factor promotes survival of rat and human mesencephalic dopaminergic neurons in culture. Exp
-
[CrossRef] [PubMed]
-
Nikkhah, G.; Odin, P.; Smits, A.; Tingström, A.; Othberg, A.; Brundin, P.; Funa, K.; Lindvall, O. Platelet-derived growth factor promotes survival of rat and human mesencephalic dopaminergic neurons in culture. Exp. Brain Res. 1993, 92, 516–523. [CrossRef] [PubMed]
-
(1993)
Brain Res
, vol.92
, pp. 516-523
-
-
Nikkhah, G.1
Odin, P.2
Smits, A.3
Tingström, A.4
Othberg, A.5
Brundin, P.6
Funa, K.7
Lindvall, O.8
-
124
-
-
0029053764
-
Specific effects of platelet derived growth factor (PDGF) on fetal rat and human dopaminergic neurons in vitro
-
[CrossRef] [PubMed]
-
Othberg, A.; Odin, P.; Ballagi, A.; Ahgren, A.; Funa, K.; Lindvall, O. Specific effects of platelet derived growth factor (PDGF) on fetal rat and human dopaminergic neurons in vitro. Exp. Brain Res. 1995, 105, 111–122. [CrossRef] [PubMed]
-
(1995)
Exp. Brain Res
, vol.105
, pp. 111-122
-
-
Othberg, A.1
Odin, P.2
Ballagi, A.3
Ahgren, A.4
Funa, K.5
Lindvall, O.6
-
125
-
-
0033390921
-
Granulocyte Colony-Stimulating Factor and Granulocyte-Macrophage Colony-Stimulating Factor: Comparisons and Potential for Use in the Treatment of Infections in Nonneutropenic Patients
-
[CrossRef] [PubMed]
-
Root, R.K.; Dale, D.C. Granulocyte Colony-Stimulating Factor and Granulocyte-Macrophage Colony-Stimulating Factor: Comparisons and Potential for Use in the Treatment of Infections in Nonneutropenic Patients. J. Infect. Dis. 1999, 179, S342–S352. [CrossRef] [PubMed]
-
(1999)
J. Infect. Dis
, vol.179
, pp. S342-S352
-
-
Root, R.K.1
Dale, D.C.2
-
126
-
-
0037338416
-
Neuroprotective effect of granulocyte colony-stimulating factor after focal cerebral ischemia. Stroke
-
[CrossRef] [PubMed]
-
Schäbitz, W.-R.; Kollmar, R.; Schwaninger, M.; Juettler, E.; Bardutzky, J.; Schölzke, M.N.; Sommer, C.; Schwab, S. Neuroprotective effect of granulocyte colony-stimulating factor after focal cerebral ischemia. Stroke J. Cereb. Circ. 2003, 34, 745–751. [CrossRef] [PubMed]
-
(2003)
J. Cereb. Circ
, vol.34
, pp. 745-751
-
-
Schäbitz, W.-R.1
Kollmar, R.2
Schwaninger, M.3
Juettler, E.4
Bardutzky, J.5
Schölzke, M.N.6
Sommer, C.7
Schwab, S.8
-
127
-
-
23644445498
-
The hematopoietic factor G-CSF is a neuronal ligand that counteracts programmed cell death and drives neurogenesis
-
[CrossRef] [PubMed]
-
Schneider, A.; Krüger, C.; Steigleder, T.; Weber, D.; Pitzer, C.; Laage, R.; Aronowski, J.; Maurer, M.H.; Gassler, N.; Mier, W.; et al. The hematopoietic factor G-CSF is a neuronal ligand that counteracts programmed cell death and drives neurogenesis. J. Clin. Investig. 2005, 115, 2083–2098. [CrossRef] [PubMed]
-
(2005)
J. Clin. Investig
, vol.115
, pp. 2083-2098
-
-
Schneider, A.1
Krüger, C.2
Steigleder, T.3
Weber, D.4
Pitzer, C.5
Laage, R.6
Aronowski, J.7
Maurer, M.H.8
Gassler, N.9
Mier, W.10
-
128
-
-
33645878579
-
Granulocyte-colony stimulating factor is neuroprotective in a model of Parkinson’s disease
-
[CrossRef] [PubMed]
-
Meuer, K.; Pitzer, C.; Teismann, P.; Krüger, C.; Göricke, B.; Laage, R.; Lingor, P.; Peters, K.; Schlachetzki, J.C.M.; Kobayashi, K.; et a. Granulocyte-colony stimulating factor is neuroprotective in a model of Parkinson’s disease. J. Neurochem. 2006, 97, 675–686. [CrossRef] [PubMed]
-
(2006)
J. Neurochem
, vol.97
, pp. 675-686
-
-
Meuer, K.1
Pitzer, C.2
Teismann, P.3
Krüger, C.4
Göricke, B.5
Laage, R.6
Lingor, P.7
Peters, K.8
Schlachetzki, J.C.M.9
Kobayashi, K.10
-
129
-
-
78650218130
-
Granulocyte-colony stimulating factor (G-CSF) enhances recovery in mouse model of Parkinson’s disease
-
[CrossRef] [PubMed]
-
Song, S.; Sava, V.; Rowe, A.; Li, K.; Cao, C.; Mori, T.; Sanchez-Ramos, J. Granulocyte-colony stimulating factor (G-CSF) enhances recovery in mouse model of Parkinson’s disease. Neurosci. Lett. 2011, 487, 153–157. [CrossRef] [PubMed]
-
(2011)
Neurosci. Lett
, vol.487
, pp. 153-157
-
-
Song, S.1
Sava, V.2
Rowe, A.3
Li, K.4
Cao, C.5
Mori, T.6
Sanchez-Ramos, J.7
-
130
-
-
33750043456
-
Recombinant human granulocyte colony-stimulating factor protects against MPTP-induced dopaminergic cell death in mice by altering Bcl-2/Bax expression levels
-
[CrossRef] [PubMed]
-
Cao, X.-Q.; Arai, H.; Ren, Y.-R.; Oizumi, H.; Zhang, N.; Seike, S.; Furuya, T.; Yasuda, T.; Mizuno, Y.; Mochizuki, H. Recombinant human granulocyte colony-stimulating factor protects against MPTP-induced dopaminergic cell death in mice by altering Bcl-2/Bax expression levels. J. Neurochem. 2006, 99, 861–867. [CrossRef] [PubMed]
-
(2006)
J. Neurochem
, vol.99
, pp. 861-867
-
-
Cao, X.-Q.1
Arai, H.2
Ren, Y.-R.3
Oizumi, H.4
Zhang, N.5
Seike, S.6
Furuya, T.7
Yasuda, T.8
Mizuno, Y.9
Mochizuki, H.10
-
131
-
-
61449227467
-
Granulocyte-macrophage colony-stimulating factor promotes survival of dopaminergic neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced murine Parkinson’s disease model
-
[CrossRef] [PubMed]
-
Kim, N.K.; Choi, B.H.; Huang, X.; Snyder, B.J.; Bukhari, S.; Kong, T.-H.; Park, H.; Park, H.C.; Park, S.R.; Ha, Y. Granulocyte-macrophage colony-stimulating factor promotes survival of dopaminergic neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced murine Parkinson’s disease model. Eur. J. Neurosci. 2009, 29, 891–900. [CrossRef] [PubMed]
-
(2009)
Eur. J. Neurosci
, vol.29
, pp. 891-900
-
-
Kim, N.K.1
Choi, B.H.2
Huang, X.3
Snyder, B.J.4
Bukhari, S.5
Kong, T.-H.6
Park, H.7
Park, H.C.8
Park, S.R.9
Ha, Y.10
-
132
-
-
84888369519
-
GM-CSF induces neuroprotective and anti-inflammatory responses in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine intoxicated mice
-
[CrossRef] [PubMed]
-
Kosloski, L.M.; Kosmacek, E.A.; Olson, K.E.; Mosley, R.L.; Gendelman, H.E. GM-CSF induces neuroprotective and anti-inflammatory responses in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine intoxicated mice. J. Neuroimmunol. 2013, 265, 1–10. [CrossRef] [PubMed]
-
(2013)
J. Neuroimmunol
, vol.265
, pp. 1-10
-
-
Kosloski, L.M.1
Kosmacek, E.A.2
Olson, K.E.3
Mosley, R.L.4
Gendelman, H.E.5
-
133
-
-
77949691167
-
Novel CDNF/MANF family of neurotrophic factors. Dev
-
[CrossRef] [PubMed]
-
Lindholm, P.; Saarma, M. Novel CDNF/MANF family of neurotrophic factors. Dev. Neurobiol. 2010, 70, 360–371. [CrossRef] [PubMed]
-
(2010)
Neurobiol
, vol.70
, pp. 360-371
-
-
Lindholm, P.1
Saarma, M.2
-
134
-
-
34447132381
-
Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo
-
[CrossRef] [PubMed]
-
Lindholm, P.; Voutilainen, M.H.; Laurén, J.; Peränen, J.; Leppänen, V.-M.; Andressoo, J.-O.; Lindahl, M.; Janhunen, S.; Kalkkinen, N.; Timmusk, T.; et al. Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo. Nature 2007, 448, 73–77. [CrossRef] [PubMed]
-
(2007)
Nature
, vol.448
, pp. 73-77
-
-
Lindholm, P.1
Voutilainen, M.H.2
Laurén, J.3
Peränen, J.4
Leppänen, V.-M.5
Andressoo, J.-O.6
Lindahl, M.7
Janhunen, S.8
Kalkkinen, N.9
Timmusk, T.10
-
135
-
-
84865493751
-
CDNF protects the nigrostriatal dopamine system and promotes recovery after MPTP treatment in mice
-
[CrossRef] [PubMed]
-
Airavaara, M.; Harvey, B.K.; Voutilainen, M.H.; Shen, H.; Chou, J.; Lindholm, P.; Lindahl, M.; Tuominen, R.K.; Saarma, M.; Hoffer, B.; et al. CDNF protects the nigrostriatal dopamine system and promotes recovery after MPTP treatment in mice. Cell Transplant. 2012, 21, 1213–1223. [CrossRef] [PubMed]
-
(2012)
Cell Transplant
, vol.21
, pp. 1213-1223
-
-
Airavaara, M.1
Harvey, B.K.2
Voutilainen, M.H.3
Shen, H.4
Chou, J.5
Lindholm, P.6
Lindahl, M.7
Tuominen, R.K.8
Saarma, M.9
Hoffer, B.10
|