IGF-1 signaling reduces neuro-inflammatory response and sensitivity of neurons to MPTP

Neurobiology of Aging

Volumn 30, Issue 12, 2009, Pages 2021-2030

  Nadjar, Agnès ^a   Berton, Olivier ^b   Guo, Shuhong ^c   Leneuve, Patricia ^d   Dovero, Sandra ^a   Diguet, Elsa ^a   Tison, François ^a   Zhao, Baolu ^c   Holzenberger, Martin ^d   Bezard, Erwan ^a  

^a UNIVERSITÉ DE BORDEAUX   (France)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c INSTITUTE OF BIOPHYSICS   (China)

^d HÔPITAL SAINT ANTOINE   (France)

Author keywords

Insulin like growth factor; Microglia; Neuro inflammation; Neurodegeneration; Oxidative stress

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; FREE RADICAL; SOMATOMEDIN C;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL STRESS; CONTROLLED STUDY; DISEASE SEVERITY; DOPAMINERGIC NERVE CELL; DOWN REGULATION; MALE; MOUSE; NERVE CELL LESION; NERVE CELL NECROSIS; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SUBSTANTIA NIGRA; WILD TYPE;

ANIMALS; CELL DEATH; DOPAMINE; ELECTRON SPIN RESONANCE SPECTROSCOPY; FREE RADICALS; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MPTP POISONING; NEUROIMMUNOMODULATION; NEURONS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OXIDATIVE STRESS; RECEPTOR, IGF TYPE 1; SIGNAL TRANSDUCTION; SUBSTANTIA NIGRA;

EID: 70349849852     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2008.02.009     Document Type: Article

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