Interleukin-18 null mice show diminished microglial activation and reduced dopaminergic neuron loss following acute 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine treatment

Neuroscience

Volumn 128, Issue 2, 2004, Pages 451-458

  Sugama, S ^a,b   Wirz, S A ^b   Barr, A M ^b   Conti, B ^b   Bartfai, T ^b   Shibasaki, T ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

dopaminergic neurons; interleukin 18; microglia; MPTP; substantia nigra; tyrosine hydroxylase

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; INTERLEUKIN 18;

ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; DISEASE COURSE; DOPAMINERGIC SYSTEM; KNOCKOUT MOUSE; MALE; MICROGLIA; MOUSE; MOUSE STRAIN; NERVE CELL; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; SUBSTANTIA NIGRA; WILD TYPE;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; ANIMALS; CELL COUNT; CORPUS STRIATUM; DOPAMINE; DOPAMINE AGENTS; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-18; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROGLIA; NERVE DEGENERATION; NEURONS; STAINING AND LABELING; SUBSTANTIA NIGRA; TYROSINE 3-MONOOXYGENASE;

EID: 4444333135     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2004.07.020     Document Type: Article

References (45)

1. R.B. Banati, S.E. Daniel, S.B. Blunt Glial pathology but absence of apoptotic nigral neurons in long-standing Parkinson's disease Mov Disord 13 1998 221 227
2. M.F. Beal Mitochondria, oxidative damage, and inflammation in Parkinson's disease Ann NY Acad Sci 991 2003 120 131
3. R.E. Coggeshall A consideration of neural counting methods Trends Neurosci 15 1992 9 13
4. B. Conti, J.W. Jahng, C. Tinti, J.H. Son, T.H. Joh Induction of interferon-gamma inducing factor in the adrenal cortex J Biol Chem 272 1997 2035 2037
5. B. Conti, L.C. Park, N.Y. Calingasan, Y. Kim, H. Kim, Y. Bae, G.E. Gibson, T.H. Joh Cultures of astrocytes and microglia express interleukin 18 Brain Res Mol Brain Res 67 1999 46 52
6. A.C. Culhane, M.D. Hall, N.J. Rothwell, G.N. Luheshi Cloning of rat brain interleukin-18 cDNA Mol Psychiatry 4 1998 362 366
7. A. Czlonkowska, M. Kohutnicka, I. Kurkowska-Jastrzebska, A. Czlonkowski Microglial reaction in MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) induced Parkinson's disease mice model Neurodegeneration 5 1996 137 143
8. L.A. DeGiorgio, C. Dibinis, T.A. Milner, M. Saji, B.T. Volpe Histological and temporal characteristics of nigral transneuronal degeneration after striatal injury Brain Res 795 1998 1 9
9. M. Delgado, D. Ganea Neuroprotective effect of vasoactive intestinal peptide (VIP) in a mouse model of Parkinson's disease by blocking microglial activation FASEB J 17 2003 944 946
10. C.A. Dinarello Interleukin-18, a proinflammatory cytokine Eur Cytokine Netw 11 2000 483 486
11. K. Esposito, A. Pontillo, M. Ciotola, C. Di Palo, E. Grella, G. Nicoletti, D. Giugliano Weight loss reduces interleukin-18 levels in obese women J Clin Endocrinol Metab 87 2002 3864 3866
12. H.J. Gundersen Stereology: the fast lane between neuroanatomy and brain function-or still only a tightrope? Acta Neurol Scand Suppl 137 1992 8 13
13. H. Hara, R.M. Friedlander, V. Gagliardini, C. Ayata, K. Fink, Z. Huang, M. Shimizu-Sasamata, J. Yuan, M.A. Moskowitz Inhibition of interleukin 1beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage Proc Natl Acad Sci USA 94 1997 2007 2012
14. S. Hayley, S.J. Crocker, P.D. Smith, T. Shree, V. Jackson-Lewis, S. Przedborski, M. Mount, R. Slack, H. Anisman, D.S. Park Regulation of dopaminergic loss by Fas in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease J Neurosci 24 2004 2045 2053
15. Y. He, S. Appel, W. Le Minocycline inhibits microglial activation and protects nigral cells after 6-hydroxydopamine injection into mouse striatum Brain Res 909 2001 187 193
16. M. Hedtjarn, A.L. Leverin, K. Eriksson, K. Blomgren, C. Mallard, H. Hagberg Interleukin-18 involvement in hypoxic-ischemic brain injury J Neurosci 22 2002 5910 5919
17. R.E. Heikkila, L. Manzino, F.S. Cabbat, R.C. Duvoisin Protection against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine by monoamine oxidase inhibitors Nature 311 1984 467 469
18. S. Jander, M. Schroeter, G. Stoll Interleukin-18 expression after focal ischemia of the rat brain: association with the late-stage inflammatory response J Cereb Blood Flow Metab 22 2002 62 70
19. P. Klevenyi, O. Andreassen, R.J. Ferrante, J.R. Schleicher Jr, R.M. Friedlander, M.F. Beal Transgenic mice expressing a dominant negative mutant interleukin-1beta converting enzyme show resistance to MPTP neurotoxicity Neuroreport 10 1999 635 638
20. I. Kurkowska-Jastrzebska, A. Wronska, M. Kohutnicka, A. Czlonkowski, A. Czlonkowska The inflammatory reaction following 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine intoxication in mouse Exp Neurol 56 1999 50 61
21. P.L. McGeer, S. Itagaki, B.E. Boyes, E.G. McGeer Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains Neurology 38 1988 1285 1291
22. P.L. McGeer, C. Schwab, A. Parent, D. Douder Presence of reactive microglia in monkey substantia nigra years after 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine administration Ann Neurol 54 2003 599 604
23. I. Mori, M.J. Hossain, K. Takeda, H. Okamura, Y. Imai, S. Kohsaka, Y. Kimura Impaired microglial activation in the brain of IL-18-gene-disrupted mice after neurovirulent influenza A virus infection Virology 287 2001 163 170
24. F. Nicoletti, I. Conget, R. Di Marco, A.M. Speciale, R. Morinigo, K. Bendtzen, R. Gomis Serum levels of the interferon-gamma-inducing cytokine interleukin-18 are increased in individuals at high risk of developing type I diabetes Diabetologia 44 2001 309 311
25. H. Okamura, H. Tsutsi, T. Komatsu, M. Yutsudo, A. Hakura, T. Tanimoto, K. Torigoe, T. Okura, Y. Nukada, K. Hattori, K. Akita, M. Namba, F. Tanabe, K. Konishi, S. Fukuda, M. Kurimoto Cloning of a new cytokine that induces IFN-gamma production by T cells Nature 378 1995 88 91
26. M. Prinz, U.K. Hanisch Murine microglial cells produce and respond to interleukin-18 J Neurochem 72 1999 2215 2218
27. M. Rabuffetti, C. Sciorati, G. Tarozzo, E. Clementi, A.A. Manfredi, M. Beltramo Inhibition of caspase-1-like activity by Ac-Tyr-Val-Ala-Asp- chloromethyl ketone induces long-lasting neuroprotection in cerebral ischemia through apoptosis reduction and decrease of proinflammatory cytokines J Neurosci 20 2000 4398 4404
28. P.J. Sansonetti, A. Phalipon, J. Arondel, K. Thirumalai, S. Banerjee, S. Akira, K. Takeda, A. Zychlinsky Caspase-1 activation of IL-1beta and IL-18 are essential for Shigella flexneri-induced inflammation Immunity 12 2000 581 590
29. Y. Seta, T. Kanda, T. Tanaka, M. Arai, K. Sekiguchi, T. Yokoyama, M. Kurimoto, J. Tamura, M. Kurabayashi Interleukin 18 in acute myocardial infarction Heart 84 2000 668
30. S. Stoll, G. Muller, M. Kurimoto, J. Saloga, T. Tanimoto, H. Yamauchi, H. Okamura, J. Knop, A.H. Enk Production of IL-18 (IFN-gamma-inducing factor) messenger RNA and functional protein by murine keratinocytes J Immunol 159 1997 298 302
31. S. Sugama, B.P. Cho, L.A. DeGiorgio, Y. Shimizu, S.S. Kim, Y.S. Kim, D.H. Shin, B.T. Volpe, D.J. Reis, S. Cho, T.H. Joh Temporal and sequential analysis of microglia in the substantia nigra following medial forebrain bundle axotomyin rat Neuroscience 116 2003 925 933
32. S. Sugama, L. Yang, B.P. Cho, L.A. DeGiorgio, S. Lorenzl, D.S. Albers, M.F. Beal, B.T. Volpe, T.H. Joh Age-related microglial activation in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(MPTP)-induced dopaminergic neurodegeneration in C57BL/6 mice Brain Res 964 2003 288 294
33. S. Sugama, B.P. Cho, H. Baker, T.H. Joh, J. Lucero, B. Conti Neurons of the superior nucleus of the medial habenula and ependymal cells express IL-18 in rat CNS Brain Res 958 2002 1 9
34. K. Takeda, H. Tsutsui, T. Yoshimoto, O. Adachi, N. Yoshida, T. Kishimoto, H. Okamura, K. Nakanishi, S. Akira Defective NK cell activity and Th1 response in IL-18-deficient mice Immunity 8 1998 383 390
35. M. Takeuchi, Y. Nishizaki, O. Sano, T. Ohta, M. Ikeda, M. Kurimoto Immunohistochemical and immuno-electron-microscopic detection of interferon-gamma-inducing factor ("interleukin-18") in mouse intestinal epithelial cells Cell Tissue Res 289 1997 499 503
36. P. Teismann, M. Vila, D.K. Choi, K. Tieu, D.C. Wu, V. Jackson-Lewis, S. Przedborski COX-2 and neurodegeneration in Parkinson's disease Ann NY Acad Sci 991 2003 272 277
37. K.T. Tipton, T.P. Singer Advances in our understanding of the mechanisms of the neurotoxicity of MPTP and related compounds J Neurochem 61 1993 1191 1206
38. H. Tsutsui, K. Nakanishi, K. Matsui, K. Higashino, H. Okamura, Y. Miyazawa, K. Kaneda IFN-gamma-inducing factor up-regulates Fas ligand-mediated cytotoxic activity of murine natural killer cell clones J Immunol 157 1996 3967 3973
39. N. Udagawa, N.J. Horwood, J. Elliott, A. Mackay, J. Owens, H. Okamura, M. Kurimoto, T.J. Chambers, T.J. Martin, M.T. Gillespie Interleukin-18 (interferon-gamma-inducing factor) is produced by osteoblasts and acts via granulocyte/macrophage colony-stimulating factor and not via interferon-gamma to inhibit osteoclast formation J Exp Med 185 1997 1005 1012
40. M. Vila, V. Jackson-Lewis, C. Guegan, D.C. Wu, P. Teismann, D.K. Choi, K. Tieu, S. Przedborski The role of glial cells in Parkinson's disease Curr Opin Neurol 14 2001 483 489
41. B.T. Volpe, J. Wildmann, C.A. Altar Brain-derived neurotrophic factor prevents the loss of nigral neurons induced by excitotoxic striatal-pallidal lesions Neuroscience 83 1998 741 748
42. R.D. Wheeler, D. Brough, R.A. Le Feuvre, K. Takeda, Y. Iwakura, G.N. Luheshi, N.J. Rothwell Interleukin-18 induces expression and release of cytokines from murine glial cells: interactions with interleukin-1 beta J Neurochem 85 2003 1412 1420
43. C.K. Wong, E.K. Li, C.Y. Ho, C.W. Lam Elevation of plasma interleukin-18 concentration is correlated with disease activity in systemic lupus erythematosus Rheumatology (Oxford) 39 2000 1078 1081
44. D.C. Wu, V. Jackson-Lewis, M. Vila, K. Tieu, P. Teismann, C. Vadseth, D.K. Choi, H. Ischiropoulos, S. Przedborski Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease J Neurosci 22 2002 1763 1771
45. L. Yang, S. Sugama, J.W. Chirichigno, J. Gregorio, S. Lorenzl, D.H. Shin, S.E. Browne, Y. Shimizu, T.H. Joh, M.F. Beal, D.S. Albers Minocycline enhances MPTP toxicity to dopaminergic neurons J Neurosci Res 74 2003 278 285