-
1
-
-
0025695511
-
The nigrostriatal dopaminergic system assessed in vivo by positron emission tomography in healthy volunteer subjects and patients with Parkinson's disease
-
Leenders KL, Salmon EP, Tyrrell P, Perani D, Brooks DJ, Sager H, et al. The nigrostriatal dopaminergic system assessed in vivo by positron emission tomography in healthy volunteer subjects and patients with Parkinson's disease. Arch Neurol 1990;47:1290-8.
-
(1990)
Arch Neurol
, vol.47
, pp. 1290-1298
-
-
Leenders, K.L.1
Salmon, E.P.2
Tyrrell, P.3
Perani, D.4
Brooks, D.J.5
Sager, H.6
-
2
-
-
0036581222
-
The GDNF family: signalling, biological functions and therapeutic value
-
Airaksinen MS, Saarma M. The GDNF family: signalling, biological functions and therapeutic value. Nat Rev Neurosci 2002;3:383-94.
-
(2002)
Nat Rev Neurosci
, vol.3
, pp. 383-394
-
-
Airaksinen, M.S.1
Saarma, M.2
-
3
-
-
0027285510
-
GDNF: a glial cell linederived neurotrophic factor for midbrain dopaminergic neurons
-
Lin LF, Doherty DH, Lile JD, Bektesh S, Collins F. GDNF: a glial cell linederived neurotrophic factor for midbrain dopaminergic neurons. Science 1993;260:1130-2.
-
(1993)
Science
, vol.260
, pp. 1130-1132
-
-
Lin, L.F.1
Doherty, D.H.2
Lile, J.D.3
Bektesh, S.4
Collins, F.5
-
4
-
-
0028109526
-
Glial cell line-derived neurotrophic factor reverses toxin-induced injury to midbrain dopaminergic neurons in vivo
-
Hoffer BJ, Hoffman A, Bowenkamp K, Huettl P, Hudson J, Martin D, et al. Glial cell line-derived neurotrophic factor reverses toxin-induced injury to midbrain dopaminergic neurons in vivo. Neurosci Lett 1994;182:107-11.
-
(1994)
Neurosci Lett
, vol.182
, pp. 107-111
-
-
Hoffer, B.J.1
Hoffman, A.2
Bowenkamp, K.3
Huettl, P.4
Hudson, J.5
Martin, D.6
-
5
-
-
0032939002
-
Protection and regeneration of nigral dopaminergic neurons by neurturin or GDNF in a partial lesion model of Parkinson's disease after administration into the striatum or the lateral ventricle
-
Rosenblad C, Kirik D, Devaux B, Moffat B, Phillips HS, Bjorklund A. Protection and regeneration of nigral dopaminergic neurons by neurturin or GDNF in a partial lesion model of Parkinson's disease after administration into the striatum or the lateral ventricle. Eur J Neurosci 1999;11:1554-66.
-
(1999)
Eur J Neurosci
, vol.11
, pp. 1554-1566
-
-
Rosenblad, C.1
Kirik, D.2
Devaux, B.3
Moffat, B.4
Phillips, H.S.5
Bjorklund, A.6
-
6
-
-
13344277993
-
Functional recovery in parkinsonian monkeys treated with GDNF
-
Gash DM, Zhang Z, Ovadia A, Cass WA, Yi A, Simmerman L, et al. Functional recovery in parkinsonian monkeys treated with GDNF. Nature 1996;380:252-5.
-
(1996)
Nature
, vol.380
, pp. 252-255
-
-
Gash, D.M.1
Zhang, Z.2
Ovadia, A.3
Cass, W.A.4
Yi, A.5
Simmerman, L.6
-
7
-
-
0029764836
-
6-hydroxydopamine induces the loss of the dopaminergic phenotype in substantia nigra neurons of the rat. A possible mechanism for restoration of the nigrostriatal circuit mediated by glial cell line-derived neurotrophic factor
-
Bowenkamp KE, David D, Lapchak PL, Henry MA, Granholm AC, Hoffer BJ, et al. 6-hydroxydopamine induces the loss of the dopaminergic phenotype in substantia nigra neurons of the rat. A possible mechanism for restoration of the nigrostriatal circuit mediated by glial cell line-derived neurotrophic factor. Exp Brain Res 1996;111:1-7.
-
(1996)
Exp Brain Res
, vol.111
, pp. 1-7
-
-
Bowenkamp, K.E.1
David, D.2
Lapchak, P.L.3
Henry, M.A.4
Granholm, A.C.5
Hoffer, B.J.6
-
8
-
-
0034659835
-
Long-term rAAV-mediated gene transfer of GDNF in the rat Parkinson's model: intrastriatal but not intranigral transduction promotes functional regeneration in the lesioned nigrostriatal system
-
Kirik D, Rosenblad C, Bjorklund A, Mandel RJ. Long-term rAAV-mediated gene transfer of GDNF in the rat Parkinson's model: intrastriatal but not intranigral transduction promotes functional regeneration in the lesioned nigrostriatal system. J Neurosci 2000;20:4686-700.
-
(2000)
J Neurosci
, vol.20
, pp. 4686-4700
-
-
Kirik, D.1
Rosenblad, C.2
Bjorklund, A.3
Mandel, R.J.4
-
9
-
-
66149096521
-
Functional effects of AAV2-GDNF on the dopaminergic nigrostriatal pathway in parkinsonian rhesus monkeys
-
Eberling JL, Kells AP, Pivirotto P, Beyer J, Bringas J, Federoff HJ, et al. Functional effects of AAV2-GDNF on the dopaminergic nigrostriatal pathway in parkinsonian rhesus monkeys. Hum Gene Ther 2009;20:511-8.
-
(2009)
Hum Gene Ther
, vol.20
, pp. 511-518
-
-
Eberling, J.L.1
Kells, A.P.2
Pivirotto, P.3
Beyer, J.4
Bringas, J.5
Federoff, H.J.6
-
10
-
-
29144524873
-
Functional reinnervation from remaining DA terminals induced by GDNF lentivirus in a rat model of early Parkinson's disease
-
Brizard M, Carcenac C, Bemelmans AP, Feuerstein C, Mallet J, Savasta M. Functional reinnervation from remaining DA terminals induced by GDNF lentivirus in a rat model of early Parkinson's disease. Neurobiol Dis 2006;21:90-101.
-
(2006)
Neurobiol Dis
, vol.21
, pp. 90-101
-
-
Brizard, M.1
Carcenac, C.2
Bemelmans, A.P.3
Feuerstein, C.4
Mallet, J.5
Savasta, M.6
-
11
-
-
18144409123
-
Effect of AdGDNF on dopaminergic neurotransmission in the striatum of 6-OHDA-treated rats
-
Smith AD, Kozlowski DA, Bohn MC, Zigmond MJ. Effect of AdGDNF on dopaminergic neurotransmission in the striatum of 6-OHDA-treated rats. Exp Neurol 2005;193:420-6.
-
(2005)
Exp Neurol
, vol.193
, pp. 420-426
-
-
Smith, A.D.1
Kozlowski, D.A.2
Bohn, M.C.3
Zigmond, M.J.4
-
12
-
-
0032850453
-
Clinicopathological findings following intraventricular glial-derived neurotrophic factor treatment in a patient with Parkinson's disease
-
Kordower JH, Palfi S, Chen EY, Ma SY, Sendera T, Cochran EJ, et al. Clinicopathological findings following intraventricular glial-derived neurotrophic factor treatment in a patient with Parkinson's disease. Ann Neurol 1999;46:419-24.
-
(1999)
Ann Neurol
, vol.46
, pp. 419-424
-
-
Kordower, J.H.1
Palfi, S.2
Chen, E.Y.3
Ma, S.Y.4
Sendera, T.5
Cochran, E.J.6
-
13
-
-
0038249170
-
Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease
-
Gill SS, Patel NK, Hotton GR, O'Sullivan K, McCarter R, Bunnage M, et al. Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease. Nat Med 2003;9:589-95.
-
(2003)
Nat Med
, vol.9
, pp. 589-595
-
-
Gill, S.S.1
Patel, N.K.2
Hotton, G.R.3
O'Sullivan, K.4
McCarter, R.5
Bunnage, M.6
-
14
-
-
0037199818
-
Dopaminergic neuroprotection and regeneration by neurturin assessed by using behavioral, biochemical and histochemical measurements in a model of progressive Parkinson's disease
-
Oiwa Y, Yoshimura R, Nakai K, Itakura T. Dopaminergic neuroprotection and regeneration by neurturin assessed by using behavioral, biochemical and histochemical measurements in a model of progressive Parkinson's disease. Brain Res 2002;947:271-83.
-
(2002)
Brain Res
, vol.947
, pp. 271-283
-
-
Oiwa, Y.1
Yoshimura, R.2
Nakai, K.3
Itakura, T.4
-
15
-
-
78349247631
-
Gene delivery of AAV2-neurturin for Parkinson's disease: a double-blind, randomised, controlled trial
-
Marks Jr WJ, Bartus RT, Siffert J, Davis CS, Lozano A, Boulis N, et al. Gene delivery of AAV2-neurturin for Parkinson's disease: a double-blind, randomised, controlled trial. Lancet Neurol 2010;9:1164-72.
-
(2010)
Lancet Neurol
, vol.9
, pp. 1164-1172
-
-
Marks Jr., W.J.1
Bartus, R.T.2
Siffert, J.3
Davis, C.S.4
Lozano, A.5
Boulis, N.6
-
16
-
-
34447132381
-
Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo
-
Lindholm P, Voutilainen MH, Laurén J, Peränen J, Leppänen VM, Andressoo JO, et al. Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo. Nature 2007;448:73-7.
-
(2007)
Nature
, vol.448
, pp. 73-77
-
-
Lindholm, P.1
Voutilainen, M.H.2
Laurén, J.3
Peränen, J.4
Leppänen, V.M.5
Andressoo, J.O.6
-
17
-
-
79851509373
-
Chronic infusion of CDNF prevents 6-OHDA-induced deficits in a rat model of Parkinson's disease
-
Voutilainen MH, Back S, Peranen J, Lindholm P, Raasmaja A, Mannisto PT, et al. Chronic infusion of CDNF prevents 6-OHDA-induced deficits in a rat model of Parkinson's disease. Exp Neurol 2011;228:99-108.
-
(2011)
Exp Neurol
, vol.228
, pp. 99-108
-
-
Voutilainen, M.H.1
Back, S.2
Peranen, J.3
Lindholm, P.4
Raasmaja, A.5
Mannisto, P.T.6
-
18
-
-
84863386718
-
CDNF protects the nigrosriatal dopamine system and promotes recovery after MPTP treatment in mice
-
In press
-
Airavaara M, Harvey BK, Voutilainen MH, Shen H, Chou J, Lindholm P, et al. CDNF protects the nigrosriatal dopamine system and promotes recovery after MPTP treatment in mice. Cell Transplant 2011; in press.
-
(2011)
Cell Transplant
-
-
Airavaara, M.1
Harvey, B.K.2
Voutilainen, M.H.3
Shen, H.4
Chou, J.5
Lindholm, P.6
-
19
-
-
0042821698
-
Diadenosine tetraphosphate protects against injuries induced by ischemia and 6-hydroxydopamine in rat brain
-
Wang Y, Chang CF, Morales M, Chiang YH, Harvey BK, Su TP, et al. Diadenosine tetraphosphate protects against injuries induced by ischemia and 6-hydroxydopamine in rat brain. J Neurosci 2003;23:7958-65.
-
(2003)
J Neurosci
, vol.23
, pp. 7958-7965
-
-
Wang, Y.1
Chang, C.F.2
Morales, M.3
Chiang, Y.H.4
Harvey, B.K.5
Su, T.P.6
-
20
-
-
0035875788
-
Vitamin D(3) attenuates 6-hydroxydopamine-induced neurotoxicity in rats
-
Wang JY, Wu JN, Cherng TL, Hoffer BJ, Chen HH, Borlongan CV, et al. Vitamin D(3) attenuates 6-hydroxydopamine-induced neurotoxicity in rats. Brain Res 2001; 904:67-75.
-
(2001)
Brain Res
, vol.904
, pp. 67-75
-
-
Wang, J.Y.1
Wu, J.N.2
Cherng, T.L.3
Hoffer, B.J.4
Chen, H.H.5
Borlongan, C.V.6
-
23
-
-
34548850609
-
Deep brain stimulation and continuous dopaminergic stimulation in advanced Parkinson's disease
-
Wolters ECh. Deep brain stimulation and continuous dopaminergic stimulation in advanced Parkinson's disease. Parkinsonism Relat Disord 2007;13(Suppl 1): S18-23.
-
(2007)
Parkinsonism Relat Disord
, vol.13
, Issue.SUPPL. 1
-
-
Wolters, E.C.H.1
|