-
1
-
-
0037422574
-
Crystal structure of saposin B reveals a dimeric shell for lipid binding
-
Ahn VE, Faull KF, Whitelegge JP, Fluharty AL, Prive GG. 2003. Crystal structure of saposin B reveals a dimeric shell for lipid binding. Proc Natl Acad Sci USA 100:38-43.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 38-43
-
-
Ahn, V.E.1
Faull, K.F.2
Whitelegge, J.P.3
Fluharty, A.L.4
Prive, G.G.5
-
2
-
-
33746482701
-
Crystal structures of saposins A and C
-
Ahn VE, Leyko P, Alattia JR, Chen L, Prive GG. 2006. Crystal structures of saposins A and C. Protein Sci 15:1849-1857.
-
(2006)
Protein Sci
, vol.15
, pp. 1849-1857
-
-
Ahn, V.E.1
Leyko, P.2
Alattia, J.R.3
Chen, L.4
Prive, G.G.5
-
3
-
-
33747130712
-
Evolution of the GDNF family ligands and receptors
-
Airaksinen MS, Holm L, Hätinen T. 2006. Evolution of the GDNF family ligands and receptors. Brain Behav Evol 68:181-190.
-
(2006)
Brain Behav Evol
, vol.68
, pp. 181-190
-
-
Airaksinen, M.S.1
Holm, L.2
Hätinen, T.3
-
4
-
-
0036581222
-
The GDNF family: Signalling, biological functions and therapeutic value
-
Airaksinen MS, Saarma M. 2002. The GDNF family: Signalling, biological functions and therapeutic value. Nat Rev Neurosci 3:383-394.
-
(2002)
Nat Rev Neurosci
, vol.3
, pp. 383-394
-
-
Airaksinen, M.S.1
Saarma, M.2
-
5
-
-
67650899072
-
Mesencephalic astrocyte-derived neurotrophic factor reduces ischemic brain injury and promotes behavioral recovery in rats
-
Airavaara M, Shen H, Kuo CC, Peränen J, Saarma M, Hoffer B, Wang Y. 2009. Mesencephalic astrocyte-derived neurotrophic factor reduces ischemic brain injury and promotes behavioral recovery in rats. J Comp Neurol 515:116-124.
-
(2009)
J Comp Neurol
, vol.515
, pp. 116-124
-
-
Airavaara, M.1
Shen, H.2
Kuo, C.C.3
Peränen, J.4
Saarma, M.5
Hoffer, B.6
Wang, Y.7
-
6
-
-
0037227430
-
Granulysin crystal structure and a structure-derived lytic mechanism
-
Anderson DH, Sawaya MR, Cascio D, Ernst W, Modlin R, Krensky A, Eisenberg D. 2003. Granulysin crystal structure and a structure-derived lytic mechanism. J Mol Biol 325:355-365.
-
(2003)
J Mol Biol
, vol.325
, pp. 355-365
-
-
Anderson, D.H.1
Sawaya, M.R.2
Cascio, D.3
Ernst, W.4
Modlin, R.5
Krensky, A.6
Eisenberg, D.7
-
7
-
-
0029061894
-
NK-lysin, a novel effector peptide of cytotoxic T and NK cells. Structure and cDNA cloning of the porcine form, induction by interleukin 2, antibacterial and antitumour activity
-
Andersson M, Gunne H, Agerberth B, Boman A, Bergman T, Sillard R, Jornvall H, et al. 1995. NK-lysin, a novel effector peptide of cytotoxic T and NK cells. Structure and cDNA cloning of the porcine form, induction by interleukin 2, antibacterial and antitumour activity. EMBO J 14:1615-1625.
-
(1995)
EMBO J
, vol.14
, pp. 1615-1625
-
-
Andersson, M.1
Gunne, H.2
Agerberth, B.3
Boman, A.4
Bergman, T.5
Sillard, R.6
Jornvall, H.7
-
8
-
-
53949086721
-
Signalling mechanisms underlying development and maintenance of dopamine neurons
-
Andressoo JO, Saarma M. 2008. Signalling mechanisms underlying development and maintenance of dopamine neurons. Curr Opin Neurobiol 18:297-306.
-
(2008)
Curr Opin Neurobiol
, vol.18
, pp. 297-306
-
-
Andressoo, J.O.1
Saarma, M.2
-
9
-
-
47349130525
-
Armet, a UPR-upregulated protein, inhibits cell proliferation and ER stress-induced cell death
-
Apostolou A, Shen Y, Liang Y, Luo J, Fang S. 2008. Armet, a UPR-upregulated protein, inhibits cell proliferation and ER stress-induced cell death. Exp Cell Res 314:2454-2467.
-
(2008)
Exp Cell Res
, vol.314
, pp. 2454-2467
-
-
Apostolou, A.1
Shen, Y.2
Liang, Y.3
Luo, J.4
Fang, S.5
-
10
-
-
33847111695
-
The neuropoietic cytokine family in development, plasticity, disease and injury
-
Bauer S, Kerr BJ, Patterson PH. 2007. The neuropoietic cytokine family in development, plasticity, disease and injury. Nat Rev Neurosci 8:221-232.
-
(2007)
Nat Rev Neurosci
, vol.8
, pp. 221-232
-
-
Bauer, S.1
Kerr, B.J.2
Patterson, P.H.3
-
11
-
-
46649111986
-
Coordination of growth and endoplasmic reticulum stress signaling by regulator of calcineurin 1 (RCAN1), a novel ATF6-inducible gene
-
Belmont PJ, Tadimalla A, Chen WJ, Martindale JJ, Thuerauf DJ, Marcinko M, Gude N, et al. 2008. Coordination of growth and endoplasmic reticulum stress signaling by regulator of calcineurin 1 (RCAN1), a novel ATF6-inducible gene. J Biol Chem 283:14012-14021.
-
(2008)
J Biol Chem
, vol.283
, pp. 14012-14021
-
-
Belmont, P.J.1
Tadimalla, A.2
Chen, W.J.3
Martindale, J.J.4
Thuerauf, D.J.5
Marcinko, M.6
Gude, N.7
-
12
-
-
33846501598
-
GDNF family receptor complexes are emerging drug targets
-
Bespalov MM, Saarma M. 2007. GDNF family receptor complexes are emerging drug targets. Trends Pharmacol Sci 28:68-74.
-
(2007)
Trends Pharmacol Sci
, vol.28
, pp. 68-74
-
-
Bespalov, M.M.1
Saarma, M.2
-
13
-
-
22544463623
-
A short guided tour through functional and structural features of saposin-like proteins
-
Bruhn H. 2005. A short guided tour through functional and structural features of saposin-like proteins. Biochem J 389:249-257.
-
(2005)
Biochem J
, vol.389
, pp. 249-257
-
-
Bruhn, H.1
-
14
-
-
5444274362
-
Ontogenic cell death in the nigrostriatal system
-
Burke RE. 2004. Ontogenic cell death in the nigrostriatal system. Cell Tissue Res 318:63-72.
-
(2004)
Cell Tissue Res
, vol.318
, pp. 63-72
-
-
Burke, R.E.1
-
15
-
-
0034959811
-
Depletion of glial cell line-derived neurotrophic factor in substantia nigra neurons of Parkinson's disease brain
-
Chauhan NB, Siegel GJ, Lee JM. 2001. Depletion of glial cell line-derived neurotrophic factor in substantia nigra neurons of Parkinson's disease brain. J Chem Neuroanat 21:277-288.
-
(2001)
J Chem Neuroanat
, vol.21
, pp. 277-288
-
-
Chauhan, N.B.1
Siegel, G.J.2
Lee, J.M.3
-
16
-
-
14044271131
-
The human protein disulphide isomerase family: Substrate interactions and functional properties
-
Ellgaard L, Ruddock LW. 2005. The human protein disulphide isomerase family: Substrate interactions and functional properties. EMBO Rep 6:28-32.
-
(2005)
EMBO Rep
, vol.6
, pp. 28-32
-
-
Ellgaard, L.1
Ruddock, L.W.2
-
17
-
-
0030848376
-
Normal polymorphism in the incomplete trinucleotide repeat of the arginine-rich protein gene
-
Evron E, Cairns P, Halachmi N, Ahrendt SA, Reed AL, Sidransky D. 1997. Normal polymorphism in the incomplete trinucleotide repeat of the arginine-rich protein gene. Cancer Res 57:2888-2889.
-
(1997)
Cancer Res
, vol.57
, pp. 2888-2889
-
-
Evron, E.1
Cairns, P.2
Halachmi, N.3
Ahrendt, S.A.4
Reed, A.L.5
Sidransky, D.6
-
18
-
-
6444244371
-
Effects of fibroblast growth factor and glial-derived neurotrophic factor on akinesia, F-DOPA uptake and dopamine cells in parkinsonian primates
-
Fontan A, Rojo A, Sanchez Pernaute R, Hernandez I, Lopez I, Castilla C, Sanchez Albisua J, et al. 2002. Effects of fibroblast growth factor and glial-derived neurotrophic factor on akinesia, F-DOPA uptake and dopamine cells in parkinsonian primates. Parkinsonism Relat Disord 8:311-323.
-
(2002)
Parkinsonism Relat Disord
, vol.8
, pp. 311-323
-
-
Fontan, A.1
Rojo, A.2
Sanchez Pernaute, R.3
Hernandez, I.4
Lopez, I.5
Castilla, C.6
Sanchez Albisua, J.7
-
19
-
-
0038249170
-
Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease
-
Gill SS, Patel NK, Hotton GR, O'sullivan K, McCarter R, Bunnage M, Brooks DJ, et al. 2003. Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease. Nat Med 9:589-595.
-
(2003)
Nat Med
, vol.9
, pp. 589-595
-
-
Gill, S.S.1
Patel, N.K.2
Hotton, G.R.3
O'sullivan, K.4
McCarter, R.5
Bunnage, M.6
Brooks, D.J.7
-
20
-
-
34047190752
-
The physiological and pharmacological role of basic fibroblast growth factor in the dopaminergic nigrostriatal system
-
Grothe C, Timmer M. 2007. The physiological and pharmacological role of basic fibroblast growth factor in the dopaminergic nigrostriatal system. Brain Res Rev 54:80-91.
-
(2007)
Brain Res Rev
, vol.54
, pp. 80-91
-
-
Grothe, C.1
Timmer, M.2
-
21
-
-
33746063730
-
Earliest changes in the left ventricular transcriptome postmyocardial infarction
-
Harpster MH, Bandyopadhyay S, Thomas DP, Ivanov PS, Keele JA, Pineguina N, Gao B, et al. 2006. Earliest changes in the left ventricular transcriptome postmyocardial infarction. Mamm Genome 17:701-715.
-
(2006)
Mamm Genome
, vol.17
, pp. 701-715
-
-
Harpster, M.H.1
Bandyopadhyay, S.2
Thomas, D.P.3
Ivanov, P.S.4
Keele, J.A.5
Pineguina, N.6
Gao, B.7
-
22
-
-
13844299352
-
Solution structure of human saposin C in a detergent environment
-
Hawkins CA, de Alba E, Tjandra N. 2005. Solution structure of human saposin C in a detergent environment. J Mol Biol 346:1381-1392.
-
(2005)
J Mol Biol
, vol.346
, pp. 1381-1392
-
-
Hawkins, C.A.1
de Alba, E.2
Tjandra, N.3
-
23
-
-
0041677606
-
Principles of interleukin (IL)-6-type cytokine signalling and its regulation
-
Heinrich PC, Behrmann I, Haan S, Hermanns HM, Muller-Newen G, Schaper F. 2003. Principles of interleukin (IL)-6-type cytokine signalling and its regulation. Biochem J 374:1-20.
-
(2003)
Biochem J
, vol.374
, pp. 1-20
-
-
Heinrich, P.C.1
Behrmann, I.2
Haan, S.3
Hermanns, H.M.4
Muller-Newen, G.5
Schaper, F.6
-
24
-
-
0028109526
-
Glial cell line-derived neurotrophic factor reverses toxin-induced injury to midbrain dopaminergic neurons in vivo
-
Hoffer BJ, Hoffman A, Bowenkamp K, Huettl P, Hudson J, Martin D, Lin LF, et al. 1994. Glial cell line-derived neurotrophic factor reverses toxin-induced injury to midbrain dopaminergic neurons in vivo. Neurosci Lett 182:107-111.
-
(1994)
Neurosci Lett
, vol.182
, pp. 107-111
-
-
Hoffer, B.J.1
Hoffman, A.2
Bowenkamp, K.3
Huettl, P.4
Hudson, J.5
Martin, D.6
Lin, L.F.7
-
25
-
-
0037397499
-
Disulfide bonds as switches for protein function
-
Hogg PJ. 2003. Disulfide bonds as switches for protein function. Trends Biochem Sci 28:210-214.
-
(2003)
Trends Biochem Sci
, vol.28
, pp. 210-214
-
-
Hogg, P.J.1
-
26
-
-
17644407706
-
Microarray expression profiling identifies early signaling transcripts associated with 6-OHDA-induced dopaminergic cell death
-
Holtz WA, Turetzky JM, O'Malley KL. 2005. Microarray expression profiling identifies early signaling transcripts associated with 6-OHDA-induced dopaminergic cell death. Antioxid Redox Signal 7:639-648.
-
(2005)
Antioxid Redox Signal
, vol.7
, pp. 639-648
-
-
Holtz, W.A.1
Turetzky, J.M.2
O'Malley, K.L.3
-
27
-
-
35748939368
-
Six-month continuous intraputamenal infusion toxicity study of recombinant methionyl human glial cell line-derived neurotrophic factor (r-metHuGDNF) in rhesus monkeys
-
Hovland DN Jr, Boyd RB, Butt MT, Engelhardt JA, Moxness MS, Ma MH, Emery MG, et al. 2007. Six-month continuous intraputamenal infusion toxicity study of recombinant methionyl human glial cell line-derived neurotrophic factor (r-metHuGDNF) in rhesus monkeys. Toxicol Pathol 35:676-692.
-
(2007)
Toxicol Pathol
, vol.35
, pp. 676-692
-
-
Hovland Jr, D.N.1
Boyd, R.B.2
Butt, M.T.3
Engelhardt, J.A.4
Moxness, M.S.5
Ma, M.H.6
Emery, M.G.7
-
28
-
-
0033762265
-
Reduced BDNF mRNA expression in the Parkinson's disease substantia nigra
-
Howells DW, Porritt MJ, Wong JY, Batchelor PE, Kalnins R, Hughes AJ, Donnan GA. 2000. Reduced BDNF mRNA expression in the Parkinson's disease substantia nigra. Exp Neurol 166:127-135.
-
(2000)
Exp Neurol
, vol.166
, pp. 127-135
-
-
Howells, D.W.1
Porritt, M.J.2
Wong, J.Y.3
Batchelor, P.E.4
Kalnins, R.5
Hughes, A.J.6
Donnan, G.A.7
-
29
-
-
0034927081
-
Neurotrophins: Roles in neuronal development and function
-
Huang EJ, Reichardt LF. 2001. Neurotrophins: Roles in neuronal development and function. Annu Rev Neurosci 24:677-736.
-
(2001)
Annu Rev Neurosci
, vol.24
, pp. 677-736
-
-
Huang, E.J.1
Reichardt, L.F.2
-
30
-
-
0028898505
-
Glial cell line-derived neurotrophic factor augments midbrain dopaminergic circuits in vivo
-
Hudson J, Granholm AC, Gerhardt GA, Henry MA, Hoffman A, Biddle P, Leela NS, et al. 1995. Glial cell line-derived neurotrophic factor augments midbrain dopaminergic circuits in vivo. Brain Res Bull 36:425-432.
-
(1995)
Brain Res Bull
, vol.36
, pp. 425-432
-
-
Hudson, J.1
Granholm, A.C.2
Gerhardt, G.A.3
Henry, M.A.4
Hoffman, A.5
Biddle, P.6
Leela, N.S.7
-
31
-
-
0023234949
-
The isolation and sequence of a novel gene from a human functional T cell line
-
Jongstra J, Schall TJ, Dyer BJ, Clayberger C, Jorgensen J, Davis MM, Krensky AM. 1987. The isolation and sequence of a novel gene from a human functional T cell line. J Exp Med 165:601-614.
-
(1987)
J Exp Med
, vol.165
, pp. 601-614
-
-
Jongstra, J.1
Schall, T.J.2
Dyer, B.J.3
Clayberger, C.4
Jorgensen, J.5
Davis, M.M.6
Krensky, A.M.7
-
32
-
-
33646698875
-
Extracellular disulfide exchange and the regulation of cellular function
-
Jordan PA, Gibbins JM. 2006. Extracellular disulfide exchange and the regulation of cellular function. Antioxid Redox Signal 8:312-324.
-
(2006)
Antioxid Redox Signal
, vol.8
, pp. 312-324
-
-
Jordan, P.A.1
Gibbins, J.M.2
-
33
-
-
74149093893
-
Characterization of meteorin - An evolutionary conserved neurotrophic factor
-
Jørgensen JR, Thompson L, Fjord-Larsen L, Krabbe C, Torp M, Kalkkinen N, Hansen C, et al. 2009. Characterization of meteorin - An evolutionary conserved neurotrophic factor. J Mol Neurosci 39:104-116.
-
(2009)
J Mol Neurosci
, vol.39
, pp. 104-116
-
-
Jørgensen, J.R.1
Thompson, L.2
Fjord-Larsen, L.3
Krabbe, C.4
Torp, M.5
Kalkkinen, N.6
Hansen, C.7
-
34
-
-
58549083938
-
Continuous intraventricular infusion of erythropoietin exerts neuroprotective/rescue effects upon Parkinson's disease model of rats with enhanced neurogenesis
-
Kadota T, Shingo T, Yasuhara T, Tajiri N, Kondo A, Morimoto T, Yuan WJ, et al. 2009. Continuous intraventricular infusion of erythropoietin exerts neuroprotective/rescue effects upon Parkinson's disease model of rats with enhanced neurogenesis. Brain Res 1254:120-127.
-
(2009)
Brain Res
, vol.1254
, pp. 120-127
-
-
Kadota, T.1
Shingo, T.2
Yasuhara, T.3
Tajiri, N.4
Kondo, A.5
Morimoto, T.6
Yuan, W.J.7
-
35
-
-
0029970341
-
Prosaposin facilitates sciatic nerve regeneration in vivo
-
Kotani Y, Matsuda S, Sakanaka M, Kondoh K, Ueno S, Sano A. 1996. Prosaposin facilitates sciatic nerve regeneration in vivo. J Neurochem 66:2019-2025.
-
(1996)
J Neurochem
, vol.66
, pp. 2019-2025
-
-
Kotani, Y.1
Matsuda, S.2
Sakanaka, M.3
Kondoh, K.4
Ueno, S.5
Sano, A.6
-
36
-
-
5444258473
-
Factors promoting survival of mesencephalic dopaminergic neurons
-
Krieglstein K. 2004. Factors promoting survival of mesencephalic dopaminergic neurons. Cell Tissue Res 318:73-80.
-
(2004)
Cell Tissue Res
, vol.318
, pp. 73-80
-
-
Krieglstein, K.1
-
37
-
-
33644833272
-
Randomized controlled trial of intraputamenal glial cell line-derived neurotrophic factor infusion in Parkinson disease
-
Lang AE, Gill S, Patel NK, Lozano A, Nutt JG, Penn R, Brooks DJ, et al. 2006. Randomized controlled trial of intraputamenal glial cell line-derived neurotrophic factor infusion in Parkinson disease. Ann Neurol 59:459-466.
-
(2006)
Ann Neurol
, vol.59
, pp. 459-466
-
-
Lang, A.E.1
Gill, S.2
Patel, N.K.3
Lozano, A.4
Nutt, J.G.5
Penn, R.6
Brooks, D.J.7
-
38
-
-
0142059951
-
XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response
-
Lee AH, Iwakoshi NN, Glimcher LH. 2003. XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response. Mol Cell Biol 23:7448-7459.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 7448-7459
-
-
Lee, A.H.1
Iwakoshi, N.N.2
Glimcher, L.H.3
-
39
-
-
0023236055
-
The nerve growth factor 35 years later
-
Levi-Montalcini R. 1987. The nerve growth factor 35 years later. Science 237:1154-1162.
-
(1987)
Science
, vol.237
, pp. 1154-1162
-
-
Levi-Montalcini, R.1
-
41
-
-
0027285510
-
GDNF: A glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons
-
Lin LF, Doherty DH, Lile JD, Bektesh S, Collins F. 1993. GDNF: A glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science 260:1130-1132.
-
(1993)
Science
, vol.260
, pp. 1130-1132
-
-
Lin, L.F.1
Doherty, D.H.2
Lile, J.D.3
Bektesh, S.4
Collins, F.5
-
42
-
-
53849102168
-
MANF is widely expressed in mammalian tissues and differently regulated after ischemic and epileptic insults in rodent brain
-
Lindholm P, Peränen J, Andressoo JO, Kalkkinen N, Kokaia Z, Lindvall O, Timmusk T, et al. 2008. MANF is widely expressed in mammalian tissues and differently regulated after ischemic and epileptic insults in rodent brain. Mol Cell Neurosci 39:356-371.
-
(2008)
Mol Cell Neurosci
, vol.39
, pp. 356-371
-
-
Lindholm, P.1
Peränen, J.2
Andressoo, J.O.3
Kalkkinen, N.4
Kokaia, Z.5
Lindvall, O.6
Timmusk, T.7
-
43
-
-
34447132381
-
Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo
-
Lindholm P, Voutilainen MH, Laurén J, Peränen J, Leppänen VM, Andressoo JO, Lindahl M, et al. 2007. Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo. Nature 448:73-77.
-
(2007)
Nature
, vol.448
, pp. 73-77
-
-
Lindholm, P.1
Voutilainen, M.H.2
Laurén, J.3
Peränen, J.4
Leppänen, V.M.5
Andressoo, J.O.6
Lindahl, M.7
-
44
-
-
0035316590
-
Prosaptide D5, a retroinverso 11-mer peptidomimetic, rescued dopaminergic neurons in a model of Parkinson's disease
-
Liu J, Wang CY, O'Brien JS. 2001. Prosaptide D5, a retroinverso 11-mer peptidomimetic, rescued dopaminergic neurons in a model of Parkinson's disease. FASEB J 15:1080-1082.
-
(2001)
FASEB J
, vol.15
, pp. 1080-1082
-
-
Liu, J.1
Wang, C.Y.2
O'Brien, J.S.3
-
45
-
-
22544461907
-
Glial cell line-derived neurotrophic factor induces neuronal sprouting in human brain
-
Love S, Plaha P, Patel NK, Hotton GR, Brooks DJ, Gill SS. 2005. Glial cell line-derived neurotrophic factor induces neuronal sprouting in human brain. Nat Med 11:703-704.
-
(2005)
Nat Med
, vol.11
, pp. 703-704
-
-
Love, S.1
Plaha, P.2
Patel, N.K.3
Hotton, G.R.4
Brooks, D.J.5
Gill, S.S.6
-
46
-
-
23044488902
-
The yin and yang of neurotrophin action
-
Lu B, Pang PT, Woo NH. 2005. The yin and yang of neurotrophin action. Nat Rev Neurosci 6:603-614.
-
(2005)
Nat Rev Neurosci
, vol.6
, pp. 603-614
-
-
Lu, B.1
Pang, P.T.2
Woo, N.H.3
-
47
-
-
34548450668
-
ARMET is a soluble ER protein induced by the unfolded protein response via ERSE-II element
-
Mizobuchi N, Hoseki J, Kubota H, Toyokuni S, Nozaki J, Naitoh M, Koizumi A, et al. 2007. ARMET is a soluble ER protein induced by the unfolded protein response via ERSE-II element. Cell Struct Funct 32:41-50.
-
(2007)
Cell Struct Funct
, vol.32
, pp. 41-50
-
-
Mizobuchi, N.1
Hoseki, J.2
Kubota, H.3
Toyokuni, S.4
Nozaki, J.5
Naitoh, M.6
Koizumi, A.7
-
48
-
-
0033597983
-
Brain-derived growth factor and nerve growth factor concentrations are decreased in the substantia nigra in Parkinson's disease
-
Mogi M, Togari A, Kondo T, Mizuno Y, Komure O, Kuno S, Ichinose H, et al. 1999. Brain-derived growth factor and nerve growth factor concentrations are decreased in the substantia nigra in Parkinson's disease. Neurosci Lett 270:45-48.
-
(1999)
Neurosci Lett
, vol.270
, pp. 45-48
-
-
Mogi, M.1
Togari, A.2
Kondo, T.3
Mizuno, Y.4
Komure, O.5
Kuno, S.6
Ichinose, H.7
-
49
-
-
3142515956
-
Meteorin: A secreted protein that regulates glial cell differentiation and promotes axonal extension
-
Nishino J, Yamashita K, Hashiguchi H, Fujii H, Shimazaki T, Hamada H. 2004. Meteorin: A secreted protein that regulates glial cell differentiation and promotes axonal extension. EMBO J 23:1998-2008.
-
(2004)
EMBO J
, vol.23
, pp. 1998-2008
-
-
Nishino, J.1
Yamashita, K.2
Hashiguchi, H.3
Fujii, H.4
Shimazaki, T.5
Hamada, H.6
-
50
-
-
0028136476
-
Identification of prosaposin as a neurotrophic factor
-
O'Brien JS, Carson GS, Seo HC, Hiraiwa M, Kishimoto Y. 1994. Identification of prosaposin as a neurotrophic factor. Proc Natl Acad Sci USA 91:9593-9596.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 9593-9596
-
-
O'Brien, J.S.1
Carson, G.S.2
Seo, H.C.3
Hiraiwa, M.4
Kishimoto, Y.5
-
51
-
-
0029013931
-
Identification of the neurotrophic factor sequence of prosaposin
-
O'Brien JS, Carson GS, Seo HC, Hiraiwa M, Weiler S, Tomich JM, Barranger JA, et al. 1995. Identification of the neurotrophic factor sequence of prosaposin. FASEB J 9:681-685.
-
(1995)
FASEB J
, vol.9
, pp. 681-685
-
-
O'Brien, J.S.1
Carson, G.S.2
Seo, H.C.3
Hiraiwa, M.4
Weiler, S.5
Tomich, J.M.6
Barranger, J.A.7
-
52
-
-
60549115250
-
Evidence that DmMANF is an invertebrate neurotrophic factor supporting dopaminergic neurons
-
Palgi M, Lindström R, Peränen J, Piepponen TP, Saarma M, Heino TI. 2009. Evidence that DmMANF is an invertebrate neurotrophic factor supporting dopaminergic neurons. Proc Natl Acad Sci USA 106:2429-2434.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 2429-2434
-
-
Palgi, M.1
Lindström, R.2
Peränen, J.3
Piepponen, T.P.4
Saarma, M.5
Heino, T.I.6
-
53
-
-
0033602009
-
Reduced expression of brain-derived neurotrophic factor protein in Parkinson's disease substantia nigra
-
Parain K, Murer MG, Yan Q, Faucheux B, Agid Y, Hirsch E, Raisman-Vozari R. 1999. Reduced expression of brain-derived neurotrophic factor protein in Parkinson's disease substantia nigra. Neuroreport 10:557-561.
-
(1999)
Neuroreport
, vol.10
, pp. 557-561
-
-
Parain, K.1
Murer, M.G.2
Yan, Q.3
Faucheux, B.4
Agid, Y.5
Hirsch, E.6
Raisman-Vozari, R.7
-
54
-
-
65349083373
-
The structure of the conserved neurotrophic factors MANF and CDNF explains why they are bifunctional
-
Parkash V, Lindholm P, Peränen J, Kalkkinen N, Oksanen E, Saarma M, Leppänen VM, et al. 2009. The structure of the conserved neurotrophic factors MANF and CDNF explains why they are bifunctional. Protein Eng Des Sel 22:233-241.
-
(2009)
Protein Eng Des Sel
, vol.22
, pp. 233-241
-
-
Parkash, V.1
Lindholm, P.2
Peränen, J.3
Kalkkinen, N.4
Oksanen, E.5
Saarma, M.6
Leppänen, V.M.7
-
55
-
-
13144282676
-
Intraputamenal infusion of glial cell line-derived neurotrophic factor in PD: A two-year outcome study
-
Patel NK, Bunnage M, Plaha P, Svendsen CN, Heywood P, Gill SS. 2005. Intraputamenal infusion of glial cell line-derived neurotrophic factor in PD: A two-year outcome study. Ann Neurol 57:298-302.
-
(2005)
Ann Neurol
, vol.57
, pp. 298-302
-
-
Patel, N.K.1
Bunnage, M.2
Plaha, P.3
Svendsen, C.N.4
Heywood, P.5
Gill, S.S.6
-
56
-
-
0031569218
-
Processing, subcellular localization, and function of 519 (granulysin), a human late T cell activation molecule with homology to small, lytic, granule proteins
-
Pena SV, Hanson DA, Carr BA, Goralski TJ, Krensky AM. 1997. Processing, subcellular localization, and function of 519 (granulysin), a human late T cell activation molecule with homology to small, lytic, granule proteins. J Immunol 158:2680-2688.
-
(1997)
J Immunol
, vol.158
, pp. 2680-2688
-
-
Pena, S.V.1
Hanson, D.A.2
Carr, B.A.3
Goralski, T.J.4
Krensky, A.M.5
-
57
-
-
0037942718
-
MANF: A new mesencephalic, astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons
-
Petrova P, Raibekas A, Pevsner J, Vigo N, Anafi M, Moore MK, Peaire AE, et al. 2003. MANF: A new mesencephalic, astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons. J Mol Neurosci 20:173-188.
-
(2003)
J Mol Neurosci
, vol.20
, pp. 173-188
-
-
Petrova, P.1
Raibekas, A.2
Pevsner, J.3
Vigo, N.4
Anafi, M.5
Moore, M.K.6
Peaire, A.E.7
-
58
-
-
33750813556
-
Lack of association between UGT1A7. UGT1A9, ARP, SPINK1 and CFTR gene polymorphisms and pancreatic cancer in Italian patients
-
Piepoli A, Gentile A, Valvano MR, Barana D, Oliani C, Cotugno R, Quitadamo M, et al. 2006. Lack of association between UGT1A7. UGT1A9, ARP, SPINK1 and CFTR gene polymorphisms and pancreatic cancer in Italian patients. World J Gastroenterol 12:6343-6348.
-
(2006)
World J Gastroenterol
, vol.12
, pp. 6343-6348
-
-
Piepoli, A.1
Gentile, A.2
Valvano, M.R.3
Barana, D.4
Oliani, C.5
Cotugno, R.6
Quitadamo, M.7
-
59
-
-
33749260912
-
HSV-mediated delivery of erythropoietin restores dopaminergic function in MPTP-treated mice
-
Puskovic V, Wolfe D, Wechuck J, Krisky D, Collins J, Glorioso JC, Fink DJ, et al. 2006. HSV-mediated delivery of erythropoietin restores dopaminergic function in MPTP-treated mice. Mol Ther 14:710-715.
-
(2006)
Mol Ther
, vol.14
, pp. 710-715
-
-
Puskovic, V.1
Wolfe, D.2
Wechuck, J.3
Krisky, D.4
Collins, J.5
Glorioso, J.C.6
Fink, D.J.7
-
60
-
-
37249041127
-
A molecular specificity code for the three mammalian KDEL receptors
-
Raykhel I, Alanen H, Salo K, Jurvansuu J, Nguyen VD, Latva-Ranta M, Ruddock L. 2007. A molecular specificity code for the three mammalian KDEL receptors. J Cell Biol 179:1193-1204.
-
(2007)
J Cell Biol
, vol.179
, pp. 1193-1204
-
-
Raykhel, I.1
Alanen, H.2
Salo, K.3
Jurvansuu, J.4
Nguyen, V.D.5
Latva-Ranta, M.6
Ruddock, L.7
-
61
-
-
4344660747
-
XBP1 is essential for survival under hypoxic conditions and is required for tumor growth
-
Romero-Ramirez L, Cao H, Nelson D, Hammond E, Lee AH, Yoshida H, Mori K, et al. 2004. XBP1 is essential for survival under hypoxic conditions and is required for tumor growth. Cancer Res 64:5943-5947.
-
(2004)
Cancer Res
, vol.64
, pp. 5943-5947
-
-
Romero-Ramirez, L.1
Cao, H.2
Nelson, D.3
Hammond, E.4
Lee, A.H.5
Yoshida, H.6
Mori, K.7
-
62
-
-
42949157906
-
Crystal structures of human saposins C and D: Implications for lipid recognition and membrane interactions
-
Rossmann M, Schultz-Heienbrok R, Behlke J, Remmel N, Alings C, Sandhoff K, Saenger W, et al. 2008. Crystal structures of human saposins C and D: Implications for lipid recognition and membrane interactions. Structure 16:809-817.
-
(2008)
Structure
, vol.16
, pp. 809-817
-
-
Rossmann, M.1
Schultz-Heienbrok, R.2
Behlke, J.3
Remmel, N.4
Alings, C.5
Sandhoff, K.6
Saenger, W.7
-
63
-
-
0028220834
-
Progressive degeneration of nigrostriatal dopamine neurons following intrastriatal terminal lesions with 6-hydroxydopamine: A combined retrograde tracing and immunocytochemical study in the rat
-
Sauer H, Oertel WH. 1994. Progressive degeneration of nigrostriatal dopamine neurons following intrastriatal terminal lesions with 6-hydroxydopamine: A combined retrograde tracing and immunocytochemical study in the rat. Neuroscience 59:401-415.
-
(1994)
Neuroscience
, vol.59
, pp. 401-415
-
-
Sauer, H.1
Oertel, W.H.2
-
64
-
-
5544229693
-
Classic toxin-induced animal models of Parkinson's disease: 6-OHDA and MPTP
-
Schober A. 2004. Classic toxin-induced animal models of Parkinson's disease: 6-OHDA and MPTP. Cell Tissue Res 318:215-224.
-
(2004)
Cell Tissue Res
, vol.318
, pp. 215-224
-
-
Schober, A.1
-
65
-
-
34447309788
-
Selective redox regulation of cytokine receptor signaling by extracellular thioredoxin-1
-
Schwertassek U, Balmer Y, Gutscher M, Weingarten L, Preuss M, Engelhard J, Winkler M, et al. 2007. Selective redox regulation of cytokine receptor signaling by extracellular thioredoxin-1. EMBO J 26:3086-3097.
-
(2007)
EMBO J
, vol.26
, pp. 3086-3097
-
-
Schwertassek, U.1
Balmer, Y.2
Gutscher, M.3
Weingarten, L.4
Preuss, M.5
Engelhard, J.6
Winkler, M.7
-
66
-
-
10544241953
-
Mutations in the arginine-rich protein gene, in lung, breast, and prostate cancers, and in squamous cell carcinoma of the head and neck
-
Shridhar R, Shridhar V, Rivard S, Siegfried JM, Pietraszkiewicz H, Ensley J, Pauley R, et al. 1996a. Mutations in the arginine-rich protein gene, in lung, breast, and prostate cancers, and in squamous cell carcinoma of the head and neck. Cancer Res 56:5576-5578.
-
(1996)
Cancer Res
, vol.56
, pp. 5576-5578
-
-
Shridhar, R.1
Shridhar, V.2
Rivard, S.3
Siegfried, J.M.4
Pietraszkiewicz, H.5
Ensley, J.6
Pauley, R.7
-
67
-
-
0029975354
-
A gene from human chromosomal band 3p21.1 encodes a highly conserved arginine-rich protein and is mutated in renal cell carcinomas
-
Shridhar V, Rivard S, Shridhar R, Mullins C, Bostick L, Sakr W, Grignon D, et al. 1996b. A gene from human chromosomal band 3p21.1 encodes a highly conserved arginine-rich protein and is mutated in renal cell carcinomas. Oncogene 12:1931-1939.
-
(1996)
Oncogene
, vol.12
, pp. 1931-1939
-
-
Shridhar, V.1
Rivard, S.2
Shridhar, R.3
Mullins, C.4
Bostick, L.5
Sakr, W.6
Grignon, D.7
-
68
-
-
8244237051
-
Mutations in the arginine-rich protein gene (ARP) in pancreatic cancer
-
Shridhar V, Rivard S, Wang X, Shridhar R, Paisley C, Mullins C, Beirnat L, et al. 1997. Mutations in the arginine-rich protein gene (ARP) in pancreatic cancer. Oncogene 14:2213-2216.
-
(1997)
Oncogene
, vol.14
, pp. 2213-2216
-
-
Shridhar, V.1
Rivard, S.2
Wang, X.3
Shridhar, R.4
Paisley, C.5
Mullins, C.6
Beirnat, L.7
-
69
-
-
28244466782
-
CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonism
-
Silva RM, Ries V, Oo TF, Yarygina O, Jackson-Lewis V, Ryu EJ, Lu PD, et al. 2005. CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonism. J Neurochem 95:974-986.
-
(2005)
J Neurochem
, vol.95
, pp. 974-986
-
-
Silva, R.M.1
Ries, V.2
Oo, T.F.3
Yarygina, O.4
Jackson-Lewis, V.5
Ryu, E.J.6
Lu, P.D.7
-
70
-
-
14844311296
-
Improvement of bilateral motor functions in patients with Parkinson disease through the unilateral intraputaminal infusion of glial cell line-derived neurotrophic factor
-
Slevin JT, Gerhardt GA, Smith CD, Gash DM, Kryscio R, Young B. 2005. Improvement of bilateral motor functions in patients with Parkinson disease through the unilateral intraputaminal infusion of glial cell line-derived neurotrophic factor. J Neurosurg 102:216-222.
-
(2005)
J Neurosurg
, vol.102
, pp. 216-222
-
-
Slevin, J.T.1
Gerhardt, G.A.2
Smith, C.D.3
Gash, D.M.4
Kryscio, R.5
Young, B.6
-
71
-
-
0028096097
-
A Drosophila homolog of human proto-oncogene ret transiently expressed in embryonic neuronal precursor cells including neuroblasts and CNS cells
-
Sugaya R, Ishimaru S, Hosoya T, Saigo K, Emori Y. 1994. A Drosophila homolog of human proto-oncogene ret transiently expressed in embryonic neuronal precursor cells including neuroblasts and CNS cells. Mech Dev 45:139-145.
-
(1994)
Mech Dev
, vol.45
, pp. 139-145
-
-
Sugaya, R.1
Ishimaru, S.2
Hosoya, T.3
Saigo, K.4
Emori, Y.5
-
72
-
-
33748775998
-
ER stress contributes to ischemia-induced cardiomyocyte apoptosis
-
Szegezdi E, Duffy A, O'Mahoney ME, Logue SE, Mylotte LA, O'Brien T, Samali A. 2006a. ER stress contributes to ischemia-induced cardiomyocyte apoptosis. Biochem Biophys Res Commun 349:1406-1411.
-
(2006)
Biochem Biophys Res Commun
, vol.349
, pp. 1406-1411
-
-
Szegezdi, E.1
Duffy, A.2
O'Mahoney, M.E.3
Logue, S.E.4
Mylotte, L.A.5
O'Brien, T.6
Samali, A.7
-
73
-
-
33748789479
-
Mediators of endoplasmic reticulum stress-induced apoptosis
-
Szegezdi E, Logue SE, Gorman AM, Samali A. 2006b. Mediators of endoplasmic reticulum stress-induced apoptosis. EMBO Rep 7:880-885.
-
(2006)
EMBO Rep
, vol.7
, pp. 880-885
-
-
Szegezdi, E.1
Logue, S.E.2
Gorman, A.M.3
Samali, A.4
-
74
-
-
58149347240
-
Mesencephalic astrocyte-derived neurotrophic factor is an ischemia-inducible secreted endoplasmic reticulum stress response protein in the heart
-
Tadimalla A, Belmont PJ, Thuerauf DJ, Glassy MS, Martindale JJ, Gude N, Sussman MA, et al. 2008. Mesencephalic astrocyte-derived neurotrophic factor is an ischemia-inducible secreted endoplasmic reticulum stress response protein in the heart. Circ Res 103:1249-1258.
-
(2008)
Circ Res
, vol.103
, pp. 1249-1258
-
-
Tadimalla, A.1
Belmont, P.J.2
Thuerauf, D.J.3
Glassy, M.S.4
Martindale, J.J.5
Gude, N.6
Sussman, M.A.7
-
75
-
-
0034186121
-
Polymorphic variation of the ARP gene on 3p21 in Japanese esophageal cancer patients
-
Tanaka H, Shimada Y, Harada H, Shinoda M, Hatooka S, Imamura M, Ishizaki K. 2000. Polymorphic variation of the ARP gene on 3p21 in Japanese esophageal cancer patients. Oncol Rep 7:591-593.
-
(2000)
Oncol Rep
, vol.7
, pp. 591-593
-
-
Tanaka, H.1
Shimada, Y.2
Harada, H.3
Shinoda, M.4
Hatooka, S.5
Imamura, M.6
Ishizaki, K.7
-
76
-
-
33745315287
-
S-nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration
-
Uehara T, Nakamura T, Yao D, Shi ZQ, Gu Z, Ma Y, Masliah E, et al. 2006. S-nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration. Nature 441:513-517.
-
(2006)
Nature
, vol.441
, pp. 513-517
-
-
Uehara, T.1
Nakamura, T.2
Yao, D.3
Shi, Z.Q.4
Gu, Z.5
Ma, Y.6
Masliah, E.7
-
77
-
-
0028948823
-
Structural analysis of saposin C and B. Complete localization of disulfide bridges
-
Vaccaro AM, Salvioli R, Barca A, Tatti M, Ciaffoni F, Maras B, Siciliano R, et al. 1995. Structural analysis of saposin C and B. Complete localization of disulfide bridges. J Biol Chem 270:9953-9960.
-
(1995)
J Biol Chem
, vol.270
, pp. 9953-9960
-
-
Vaccaro, A.M.1
Salvioli, R.2
Barca, A.3
Tatti, M.4
Ciaffoni, F.5
Maras, B.6
Siciliano, R.7
-
78
-
-
0025787230
-
Glycosphingolipid specificity of the human sulfatide activator protein
-
Vogel A, Schwarzmann G, Sandhoff K. 1991. Glycosphingolipid specificity of the human sulfatide activator protein. Eur J Biochem 200:591-597.
-
(1991)
Eur J Biochem
, vol.200
, pp. 591-597
-
-
Vogel, A.1
Schwarzmann, G.2
Sandhoff, K.3
-
79
-
-
68049127516
-
Mesencephalic astrocyte-derived neurotrophic factor is neurorestorative in rat model of Parkinson's disease
-
Voutilainen MH, Bäck S, Pörsti E, Toppinen L, Lindgren L, Lindholm P, Peränen J, et al. 2009. Mesencephalic astrocyte-derived neurotrophic factor is neurorestorative in rat model of Parkinson's disease. J Neurosci 29:9651-9659.
-
(2009)
J Neurosci
, vol.29
, pp. 9651-9659
-
-
Voutilainen, M.H.1
Bäck, S.2
Pörsti, E.3
Toppinen, L.4
Lindgren, L.5
Lindholm, P.6
Peränen, J.7
-
80
-
-
23644431519
-
Neurorescue effects of VEGF on a rat model of Parkinson's disease
-
Yasuhara T, Shingo T, Muraoka K, Kameda M, Agari T, Wen Ji Y, Hayase H, et al. 2005. Neurorescue effects of VEGF on a rat model of Parkinson's disease. Brain Res 1053:10-18.
-
(2005)
Brain Res
, vol.1053
, pp. 10-18
-
-
Yasuhara, T.1
Shingo, T.2
Muraoka, K.3
Kameda, M.4
Agari, T.5
Wen Ji, Y.6
Hayase, H.7
-
82
-
-
56849126862
-
Drosophila neurotrophins reveal a common mechanism for nervous system formation
-
Zhu B, Pennack JA, McQuilton P, Forero MG, Mizuguchi K, Sutcliffe B, Gu CJ, et al. 2008. Drosophila neurotrophins reveal a common mechanism for nervous system formation. PLoS Biol 6:e284.
-
(2008)
PLoS Biol
, vol.6
-
-
Zhu, B.1
Pennack, J.A.2
McQuilton, P.3
Forero, M.G.4
Mizuguchi, K.5
Sutcliffe, B.6
Gu, C.J.7
|