Surviving at a Distance: Organ-Specific Metastasis

Trends in Cancer

Volumn 1, Issue 1, 2015, Pages 76-91

  Obenauf, Anna C ^a   Massagué, Joan ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Cancer; metastasis; metastatic colonization; organ specific metastasis

Indexed keywords

ANTIBODY SPECIFICITY; BONE ATROPHY; BONE MARROW CANCER; BONE METASTASIS; BRAIN METASTASIS; CANCER CELL; CANCER GROWTH; CANCER LOCALIZATION; CANCER MORTALITY; CANCER STAGING; CANCER SURVIVAL; CELL INFILTRATION; CELL SURVIVAL; CLINICAL ASSESSMENT; CLINICAL FEATURE; DISSEMINATED CANCER; DISTANT METASTASIS; HUMAN; LIVER METASTASIS; LUNG METASTASIS; NONHUMAN; OSTEOLYSIS; REVIEW; SOLID TUMOR; TROPISM; TUMOR MICROENVIRONMENT; WNT SIGNALING PATHWAY;

EID: 84955461015     PISSN: 24058033     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.trecan.2015.07.009     Document Type: Review

References (133)

1. D.X. Nguyen, and et al. Metastasis: from dissemination to organ-specific colonization Nat. Rev. Cancer 9 2009 274 284
2. S. Valastyan, and R.A. Weinberg Tumor metastasis: molecular insights and evolving paradigms Cell 147 2011 275 292
3. P.S. Steeg Tumor metastasis: mechanistic insights and clinical challenges Nat. Med. 12 2006 895 904
4. G. Disibio, and S.W. French Metastatic patterns of cancers: results from a large autopsy study Arch. Pathol. Lab. Med. 132 2008 931 939
5. J. Budczies, and et al. The landscape of metastatic progression patterns across major human cancers Oncotarget 6 2015 570 583
6. J. Urosevic, and et al. Colon cancer cells colonize the lung from established liver metastases through p38 MAPK signalling and PTHLH Nat. Cell Biol. 16 2014 685 694
7. S. Paget The distribution of secondary growths in cancer of the breast. 1889 Cancer Metastasis Rev. 8 1989 98 101
8. I.J. Fidler The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited Nat. Rev. Cancer 3 2003 453 458
9. H. Kennecke, and et al. Metastatic behavior of breast cancer subtypes J. Clin. Oncol. 28 2010 3271 3277
10. A. Soni, and et al. Breast cancer subtypes predispose the site of distant metastases Am. J. Clin. Pathol. 143 2015 471 478
11. M. Smid, and et al. Subtypes of breast cancer show preferential site of relapse Cancer Res. 68 2008 3108 3114
12. A.F. Chambers, and et al. Dissemination and growth of cancer cells in metastatic sites Nat. Rev. Cancer 2 2002 563 572
13. Y. Kienast, and et al. Real-time imaging reveals the single steps of brain metastasis formation Nat. Med. 16 2010 116 122
14. P.D. Bos, and et al. Genes that mediate breast cancer metastasis to the brain Nature 459 2009 1005 1009
15. S.F. Tavazoie, and et al. Endogenous human microRNAs that suppress breast cancer metastasis Nature 451 2008 147 152
16. A.J. Minn, and et al. Distinct organ-specific metastatic potential of individual breast cancer cells and primary tumors J. Clin. Invest. 115 2005 44 55
17. S. Vanharanta, and et al. Loss of the multifunctional RNA-binding protein RBM47 as a source of selectable metastatic traits in breast cancer Elife 3 2014 e02734
18. S. Vanharanta, and et al. Epigenetic expansion of VHL-HIF signal output drives multiorgan metastasis in renal cancer Nat. Med. 19 2013 50 56
19. M.Y. Kim, and et al. Tumor self-seeding by circulating cancer cells Cell 139 2009 1315 1326
20. D.X. Nguyen, and et al. WNT/TCF signaling through LEF1 and HOXB9 mediates lung adenocarcinoma metastasis Cell 138 2009 51 62
21. X.H. Zhang, and et al. Latent bone metastasis in breast cancer tied to Src-dependent survival signals Cancer Cell 16 2009 67 78
22. G.P. Gupta, and et al. Identifying site-specific metastasis genes and functions Cold Spring Harb. Symp. Quant. Biol. 70 2005 149 158
23. W.K. Cheung, and et al. Control of alveolar differentiation by the lineage transcription factors GATA6 and HOPX inhibits lung adenocarcinoma metastasis Cancer Cell 23 2013 725 738
24. Y. Kang, and et al. A multigenic program mediating breast cancer metastasis to bone Cancer Cell 3 2003 537 549
25. F. Xing, and et al. Reactive astrocytes promote the metastatic growth of breast cancer stem-like cells by activating Notch signalling in brain EMBO Mol. Med. 5 2013 384 396
26. A. Myoui, and et al. C-SRC tyrosine kinase activity is associated with tumor colonization in bone and lung in an animal model of human breast cancer metastasis Cancer Res. 63 2013 5028 5033
27. A. Calon, and et al. Dependency of colorectal cancer on a TGF-beta-driven program in stromal cells for metastasis initiation Cancer Cell 22 2012 571 584
28. X. Lu, and et al. VCAM-1 promotes osteolytic expansion of indolent bone micrometastasis of breast cancer by engaging alpha4beta1-positive osteoclast progenitors Cancer Cell 20 2011 701 714
29. T.R. Cox, and et al. The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase Nature 522 2015 106 110
30. N. Sethi, and et al. Tumor-derived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells Cancer Cell 19 2011 192 205
31. B. Ell, and et al. Tumor-induced osteoclast miRNA changes as regulators and biomarkers of osteolytic bone metastasis Cancer Cell 24 2013 542 556
32. M. Greaves, and C.C. Maley Clonal evolution in cancer Nature 481 2012 306 313
33. K. Naxerova, and R.K. Jain Using tumour phylogenetics to identify the roots of metastasis in humans Nat. Rev. Clin. Oncol. 12 2015 258 272
34. C.A. Klein Selection and adaptation during metastatic cancer progression Nature 501 2013 365 372
35. M.K. Hong, and et al. Tracking the origins and drivers of subclonal metastatic expansion in prostate cancer Nat. Commun. 6 2015 6605
36. G. Gundem, and et al. The evolutionary history of lethal metastatic prostate cancer Nature 520 2015 353 357
37. S.S. McAllister, and R.A. Weinberg The tumour-induced systemic environment as a critical regulator of cancer progression and metastasis Nat. Cell Biol. 16 2014 717 727
38. T. Kitamura, and et al. Immune cell promotion of metastasis Nat. Rev. Immunol. 15 2015 73 86
39. D.F. Quail, and J.A. Joyce Microenvironmental regulation of tumor progression and metastasis Nat. Med. 19 2013 1423 1437
40. D. Hanahan, and L.M. Coussens Accessories to the crime: functions of cells recruited to the tumor microenvironment Cancer Cell 21 2012 309 322
41. K.N. Weilbaecher, and et al. Cancer to bone: a fatal attraction Nat. Rev. Cancer 11 2011 411 425
42. D.H. Jones, and et al. Regulation of cancer cell migration and bone metastasis by RANKL Nature 440 2006 692 696
43. I. Vivanco, and C.L. Sawyers The phosphatidylinositol 3-Kinase AKT pathway in human cancer Nat. Rev. Cancer 2 2002 489 501
44. J. Xu, and et al. Regulation of the Src-PP2A interaction in tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis J. Biol. Chem. 288 2013 33263 33271
45. T. Oskarsson, and et al. Metastatic stem cells: sources, niches, and vital pathways Cell Stem Cell 14 2014 306 321
46. Y. Shiozawa, and et al. Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow J. Clin. Invest. 121 2011 1298 1312
47. H. Wang, and et al. The osteogenic niche promotes early-stage bone colonization of disseminated breast cancer cells Cancer Cell 27 2015 193 210
48. T. Michigami, and et al. Cell-cell contact between marrow stromal cells and myeloma cells via VCAM-1 and alpha(4)beta(1)-integrin enhances production of osteoclast-stimulating activity Blood 96 2000 1953 1960
49. N. Matsuura, and et al. Induction of experimental bone metastasis in mice by transfection of integrin alpha 4 beta 1 into tumor cells Am. J. Pathol. 148 1996 55 61
50. T.A. Guise, and et al. Basic mechanisms responsible for osteolytic and osteoblastic bone metastases Clin. Cancer Res. 12 2006 6213s 6216s
51. C.J. Logothetis, and S.H. Lin Osteoblasts in prostate cancer metastasis to bone Nat. Rev. Cancer 5 2005 21 28
52. A.C. Chiang, and J. Massague Molecular basis of metastasis N. Engl. J. Med. 359 2008 2814 2823
53. T.A. Guise, and et al. Role of endothelin-1 in osteoblastic bone metastases Cancer 97 Suppl. 3 2003 779 784
54. C.L. Hall, and et al. Prostate cancer cells promote osteoblastic bone metastases through Wnts Cancer Res. 65 2005 7554 7560
55. J. Dai, and et al. Vascular endothelial growth factor contributes to the prostate cancer-induced osteoblast differentiation mediated by bone morphogenetic protein Cancer Res. 64 2004 994 999
56. G.R. Mundy Metastasis to bone: causes, consequences and therapeutic opportunities Nat. Rev. Cancer 2 2002 584 593
57. C.C. Lynch, and et al. MMP-7 promotes prostate cancer-induced osteolysis via the solubilization of RANKL Cancer Cell 7 2005 485 496
58. X. Lu, and et al. ADAMTS1 and MMP1 proteolytically engage EGF-like ligands in an osteolytic signaling cascade for bone metastasis Genes Dev. 23 2009 1882 1894
59. P. Juarez, and T.A. Guise TGF-beta in cancer and bone: implications for treatment of bone metastases Bone 48 2011 23 29
60. J.J. Yin, and et al. TGF-beta signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development J. Clin. Invest. 103 1999 197 206
61. D. Javelaud, and et al. Stable overexpression of Smad7 in human melanoma cells impairs bone metastasis Cancer Res. 67 2007 2317 2324
62. P.G. Fournier, and et al. The TGF-β signaling regulator PMEPA1 suppresses prostate cancer metastases to bone Cancer Cell 27 2015 809 821
63. D. Padua, and et al. TGFbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4 Cell 133 2008 66 77
64. M. Tichet, and et al. Tumour-derived SPARC drives vascular permeability and extravasation through endothelial VCAM1 signalling to promote metastasis Nat. Commun. 6 2015 6993
65. R.L. Huang, and et al. ANGPTL4 modulates vascular junction integrity by integrin signaling and disruption of intercellular VE-cadherin and claudin-5 clusters Blood 118 2011 3990 4002
66. G.P. Gupta, and et al. Mediators of vascular remodelling co-opted for sequential steps in lung metastasis Nature 446 2007 765 770
67. I. Malanchi, and et al. Interactions between cancer stem cells and their niche govern metastatic colonization Nature 481 2012 85 89
68. I. Kii, and et al. Incorporation of tenascin-C into the extracellular matrix by periostin underlies an extracellular meshwork architecture J. Biol. Chem. 285 2010 2028 2039
69. T. Oskarsson, and et al. Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs Nat. Med. 17 2011 867 874
70. + stromal cells are important for metastatic colonization Proc. Natl. Acad. Sci. U.S.A. 108 2011 16002 16007
71. Q. Chen, and et al. Macrophage binding to receptor VCAM-1 transmits survival signals in breast cancer cells that invade the lungs Cancer Cell 20 2011 538 549
72. G.P. Gupta, and et al. ID genes mediate tumor reinitiation during breast cancer lung metastasis Proc. Natl. Acad. Sci. U.S.A. 104 2007 19506 19511
73. M. Stankic, and et al. TGF-beta-Id1 signaling opposes Twist1 and promotes metastatic colonization via a mesenchymal-to-epithelial transition Cell Rep. 5 2013 1228 1242
74. M. Korpal, and et al. Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization Nat. Med. 17 2011 1101 1108
75. M.S. Sosa, and et al. Mechanisms of disseminated cancer cell dormancy: an awakening field Nat. Rev. Cancer 14 2014 611 622
76. H. Gao, and et al. The BMP inhibitor Coco reactivates breast cancer cells at lung metastatic sites Cell 150 2012 764 779
77. A.F. Eichler, and et al. The biology of brain metastases - translation to new therapies Nat. Rev. Clin. Oncol. 8 2011 344 356
78. N.J. Abbott, and et al. Astrocyte-endothelial interactions at the blood-brain barrier Nat. Rev. Neurosci. 7 2006 41 53
79. L. Sevenich, and J.A. Joyce Pericellular proteolysis in cancer Genes Dev. 28 2014 2331 2347
80. W. Zhou, and et al. Cancer-secreted miR-105 destroys vascular endothelial barriers to promote metastasis Cancer Cell 25 2014 501 515
81. D.P. Fitzgerald, and et al. Reactive glia are recruited by highly proliferative brain metastases of breast cancer and promote tumor cell colonization Clin. Exp. Metastasis 25 2008 799 810
82. W.P. Leenders, and et al. Vessel co-option: how tumors obtain blood supply in the absence of sprouting angiogenesis Endothelium 9 2002 83 87
83. B. Kusters, and et al. The pattern of metastasis of human melanoma to the central nervous system is not influenced by integrin alpha(v)beta(3) expression Int. J. Cancer 92 2001 176 180
84. M. Valiente, and et al. Serpins promote cancer cell survival and vascular co-option in brain metastasis Cell 156 2014 1002 1016
85. G. Rahmathulla, and et al. The molecular biology of brain metastasis J. Oncol. 2012 2012 723541
86. M. Lorger, and et al. Activation of tumor cell integrin alphavbeta3 controls angiogenesis and metastatic growth in the brain Proc. Natl. Acad. Sci. U.S.A. 106 2009 10666 10671
87. T. Yoshimasu, and et al. Increased expression of integrin alpha3beta1 in highly brain metastatic subclone of a human non-small cell lung cancer cell line Cancer Sci. 95 2004 142 148
88. W.S. Carbonell, and et al. The vascular basement membrane as 'soil' in brain metastasis PLoS ONE 4 2009 e5857
89. S.J. Kim, and et al. Astrocytes upregulate survival genes in tumor cells and induce protection from chemotherapy Neoplasia 13 2011 286 298
90. S.W. Kim, and et al. Role of the endothelin axis in astrocyte- and endothelial cell-mediated chemoprotection of cancer cells Neuro Oncol. 16 2014 1585 1598
91. J. Neman, and et al. Co-evolution of breast-to-brain metastasis and neural progenitor cells Clin. Exp. Metastasis 30 2013 753 768
92. E. Louie, and et al. Neurotrophin-3 modulates breast cancer cells and the microenvironment to promote the growth of breast cancer brain metastasis Oncogene 32 2013 4064 4077
93. J. Neman, and et al. Human breast cancer metastases to the brain display GABAergic properties in the neural niche Proc. Natl. Acad. Sci. U.S.A. 111 2014 984 989
94. A. Kafka, and et al. Brain metastases from lung cancer show increased expression of DVL1, DVL3 and beta-catenin and down-regulation of E-cadherin Int. J. Mol. Sci. 15 2014 10635 10651
95. E. Deneve, and et al. Capture of viable circulating tumor cells in the liver of colorectal cancer patients Clin. Chem. 59 2013 1384 1392
96. A.D. Singh, and et al. Uveal melanoma: epidemiologic aspects Ophthalmol. Clin. North Am. 18 2005 75 84
97. K. Takeda, and et al. Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells Nat. Med. 7 2001 94 100
98. S. Tabaries, and et al. Claudin-2 promotes breast cancer liver metastasis by facilitating tumor cell interactions with hepatocytes Mol. Cell. Biol. 32 2012 2979 2991
99. B. Costa-Silva, and et al. Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver Nat. Cell Biol. 17 2015 816 826
100. L. Zhao, and et al. Recruitment of a myeloid cell subset (CD11b/Gr1 mid) via CCL2/CCR2 promotes the development of colorectal cancer liver metastasis Hepatology 57 2013 829 839
101. N.E. Reticker-Flynn, and S.N. Bhatia Aberrant glycosylation promotes lung cancer metastasis through adhesion to galectins in the metastatic niche Cancer Discov. 5 2015 168 181
102. F.T. Liu, and G.A. Rabinovich Galectins as modulators of tumour progression Nat. Rev. Cancer 5 2005 29 41
103. J.M. Loo, and et al. Extracellular metabolic energetics can promote cancer progression Cell 160 2015 393 406
104. S. Nagrath, and et al. Isolation of rare circulating tumour cells in cancer patients by microchip technology Nature 450 2007 1235 1239
105. Y. Husemann, and et al. Systemic spread is an early step in breast cancer Cancer Cell 13 2008 58 68
106. J.A. Schardt, and et al. Genomic analysis of single cytokeratin-positive cells from bone marrow reveals early mutational events in breast cancer Cancer Cell 8 2005 227 239
107. A.D. Rhim, and et al. EMT and dissemination precede pancreatic tumor formation Cell 148 2012 349 361
108. K. Podsypanina, and et al. Seeding and propagation of untransformed mouse mammary cells in the lung Science 321 2008 1841 1844
109. J.K. Stephens, and et al. Fatal transfer of malignant melanoma from multiorgan donor to four allograft recipients Transplantation 70 2000 232 236
110. D.C. Strauss, and J.M. Thomas Transmission of donor melanoma by organ transplantation Lancet Oncol. 11 2010 790 796
111. G. Riethmuller, and C.A. Klein Early cancer cell dissemination and late metastatic relapse: clinical reflections and biological approaches to the dormancy problem in patients Semin. Cancer Biol. 11 2001 307 311
112. S. Bao, and et al. Periostin potently promotes metastatic growth of colon cancer by augmenting cell survival via the Akt/PKB pathway Cancer Cell 5 2004 329 339
113. M. Egeblad, and Z. Werb New functions for the matrix metalloproteinases in cancer progression Nat. Rev. Cancer 2 2002 161 174
114. K. Wu, and et al. Roles of the cyclooxygenase 2 matrix metalloproteinase 1 pathway in brain metastasis of breast cancer J. Biol. Chem. 290 2015 9842 9854
115. N. McGranahan, and C. Swanton Biological and therapeutic impact of intratumor heterogeneity in cancer evolution Cancer Cell 27 2015 15 26
116. D.P. Tabassum, and K. Polyak Tumorigenesis: it takes a village Nat. Rev. Cancer 15 2015 473 483
117. A.S. Cleary, and et al. Tumour cell heterogeneity maintained by cooperating subclones in Wnt-driven mammary cancers Nature 508 2014 113 117
118. A. Marusyk, and et al. Non-cell-autonomous driving of tumour growth supports sub-clonal heterogeneity Nature 514 2014 54 58
119. J. Calbo, and et al. A functional role for tumor cell heterogeneity in a mouse model of small cell lung cancer Cancer Cell 19 2011 244 256
120. N. Aceto, and et al. Circulating tumor cell clusters are oligoclonal precursors of breast cancer metastasis Cell 158 2014 1110 1122
121. A.C. Obenauf, and et al. Therapy-induced tumour secretomes promote resistance and tumour progression Nature 520 2015 368 372
122. L. Wan, and et al. Tumor metastasis: moving new biological insights into the clinic Nat. Med. 19 2013 1450 1464
123. K. Kessenbrock, and et al. Matrix metalloproteinases: regulators of the tumor microenvironment Cell 141 2010 52 67
124. J.A. Joyce, and J.W. Pollard Microenvironmental regulation of metastasis Nat. Rev. Cancer 9 2009 239 252
125. K.V. Nguyen-Ngoc, and et al. ECM microenvironment regulates collective migration and local dissemination in normal and malignant mammary epithelium Proc. Natl. Acad. Sci. U.S.A. 109 2012 E2595 E2604
126. J.B. Wyckoff, and et al. Direct visualization of macrophage-assisted tumor cell intravasation in mammary tumors Cancer Res. 67 2007 2649 2656
127. J. Condeelis, and J.E. Segall Intravital imaging of cell movement in tumours Nat. Rev. Cancer 3 2003 921 930
128. R. Kalluri, and M. Zeisberg Fibroblasts in cancer Nat. Rev. Cancer 6 2006 392 401
129. W.L. Tam, and R.A. Weinberg The epigenetics of epithelial-mesenchymal plasticity in cancer Nat. Med. 19 2013 1438 1449
130. J.P. Thiery, and et al. Epithelial-mesenchymal transitions in development and disease Cell 139 2009 871 890
131. G.F. Nash, and et al. Platelets and cancer Lancet Oncol. 3 2002 425 430
132. G.P. Gupta, and J. Massague Cancer metastasis: building a framework Cell 127 2006 679 695
133. H. Wang, and et al. Tumor cell alpha3beta1 integrin and vascular laminin-5 mediate pulmonary arrest and metastasis J. Cell Biol. 164 2004 935 941