-
1
-
-
27644546807
-
Brain metastases: Epidemiology and pathophysiology
-
DOI 10.1007/s11060-004-8093-6
-
Gavrilovic, I. T. & Posner, J. B. Brain metastases: epidemiology and pathophysiology. J. Neurooncol. 75, 5-14 (2005). (Pubitemid 41548673)
-
(2005)
Journal of Neuro-Oncology
, vol.75
, Issue.1
, pp. 5-14
-
-
Gavrilovic, I.T.1
Posner, J.B.2
-
2
-
-
4344694453
-
Incidence proportions of brain metastases in patients diagnosed (1973 to 2001) in the Metropolitan Detroit Cancer Surveillance System
-
DOI 10.1200/JCO.2004.12.149
-
Barnholtz-Sloan, J. S. et al. Incidence proportions of brain metastases in patients diagnosed (1973 to 2001) in the Metropolitan Detroit Cancer Surveillance System. J. Clin. Oncol. 22, 2865-2872 (2004). (Pubitemid 41079905)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.14
, pp. 2865-2872
-
-
Barnholtz-Sloan, J.S.1
Sloan, A.E.2
Davis, F.G.3
Vigneau, F.D.4
Lai, P.5
Sawaya, R.E.6
-
3
-
-
0037093972
-
Incidence of brain metastases in a cohort of patients with carcinoma of the breast, colon, kidney, and lung and melanoma
-
DOI 10.1002/cncr.10541
-
Schouten, L. J., Rutten, J., Huveneers, H. A. & Twijnstra, A. Incidence of brain metastases in a cohort of patients with carcinoma of the breast, colon, kidney, and lung and melanoma. Cancer 94, 2698-2705 (2002). (Pubitemid 34478086)
-
(2002)
Cancer
, vol.94
, Issue.10
, pp. 2698-2705
-
-
Schouten, L.J.1
Rutten, J.2
Huveneers, H.A.M.3
Twijnstra, A.4
-
4
-
-
0023885240
-
Distribution of brain metastases
-
Delattre, J. Y., Krol, G., Thaler, H. T. & Posner, J. B. Distribution of brain metastases. Arch. Neurol. 45, 741-744 (1988).
-
(1988)
Arch. Neurol.
, vol.45
, pp. 741-744
-
-
Delattre, J.Y.1
Krol, G.2
Thaler, H.T.3
Posner, J.B.4
-
5
-
-
33846964491
-
A pilot study of neurocognitive function in patients with one to three new brain metastases initially treated with stereotactic radiosurgery alone
-
Chang, E. L. et al. A pilot study of neurocognitive function in patients with one to three new brain metastases initially treated with stereotactic radiosurgery alone. Neurosurgery 60, 277-283 (2007).
-
(2007)
Neurosurgery
, vol.60
, pp. 277-283
-
-
Chang, E.L.1
-
6
-
-
0037676125
-
Survival and neurologic outcomes in a randomized trial of motexafin gadolinium and whole-brain radiation therapy in brain metastases
-
DOI 10.1200/JCO.2003.12.122
-
Mehta, M. P. et al. Survival and neurologic outcomes in a randomized trial of motexafin gadolinium and whole-brain radiation therapy in brain metastases. J. Clin. Oncol. 21, 2529-2536 (2003). (Pubitemid 46606335)
-
(2003)
Journal of Clinical Oncology
, vol.21
, Issue.13
, pp. 2529-2536
-
-
Mehta, M.P.1
Rodrigus, P.2
Terhaard, C.H.J.3
Rao, A.4
Suh, J.5
Roa, W.6
Souhami, L.7
Bezjak, A.8
Leibenhaut, M.9
Komaki, R.10
Schultz, C.11
Timmerman, R.12
Curran, W.13
Smith, J.14
Phan, S.-C.15
Miller, R.A.16
Renschler, M.F.17
-
7
-
-
0030973660
-
Recursive Partitioning Analysis (RPA) of prognostic factors in three Radiation Therapy Oncology Group (RTOG) brain metastases trials
-
DOI 10.1016/S0360-3016(96)00619-0, PII S0360301696006190
-
Gaspar, L. et al. Recursive partitioning analysis (RPA) of prognostic factors in three Radiation Therapy Oncology Group (RTOG) brain metastases trials. Int. J. Radiat. Oncol. Biol. Phys. 37, 745-751 (1997). (Pubitemid 27181303)
-
(1997)
International Journal of Radiation Oncology Biology Physics
, vol.37
, Issue.4
, pp. 745-751
-
-
Gaspar, L.1
Scott, C.2
Rotman, M.3
Asbell, S.4
Phillips, T.5
Wasserman, T.6
McKenna, W.G.7
Byhardt, R.8
-
8
-
-
44649105611
-
Brain metastases in breast cancer: Clinical and pathologic characteristics associated with improvements in survival
-
Melisko, M. E., Moore, D. H., Sneed, P. K., De Franco, J. & Rugo, H. S. Brain metastases in breast cancer: clinical and pathologic characteristics associated with improvements in survival. J. Neurooncol. 88, 359-365 (2008).
-
(2008)
J. Neurooncol.
, vol.88
, pp. 359-365
-
-
Melisko, M.E.1
Moore, D.H.2
Sneed, P.K.3
De Franco, J.4
Rugo, H.S.5
-
9
-
-
52049083921
-
Survival in patients with brain metastases from breast cancer: The importance of HER-2 status
-
Eichler, A. F. et al. Survival in patients with brain metastases from breast cancer: the importance of HER-2 status. Cancer 112, 2359-2367 (2008).
-
(2008)
Cancer
, vol.112
, pp. 2359-2367
-
-
Eichler, A.F.1
-
10
-
-
78650127780
-
EGFR mutation status and survival after diagnosis of brain metastasis in nonsmall cell lung cancer
-
Eichler, A. F. et al. EGFR mutation status and survival after diagnosis of brain metastasis in nonsmall cell lung cancer. Neuro Oncol. 12, 1193-1199 (2010).
-
(2010)
Neuro Oncol.
, vol.12
, pp. 1193-1199
-
-
Eichler, A.F.1
-
11
-
-
0025189608
-
A randomized trial of surgery in the treatment of single metastases to the brain
-
Patchell, R. A. et al. A randomized trial of surgery in the treatment of single metastases to the brain. N. Engl. J. Med. 322, 494-500 (1990). (Pubitemid 20067825)
-
(1990)
New England Journal of Medicine
, vol.322
, Issue.8
, pp. 494-500
-
-
Patchell, R.A.1
Tibbs, P.A.2
Walsh, J.W.3
Dempsey, R.J.4
Maruyama, Y.5
Kryscio, R.J.6
Markesbery, W.R.7
Macdonald, J.S.8
Young, B.9
-
12
-
-
0027217452
-
Treatment of single brain metastasis: Radiotherapy alone or combined with neurosurgery?
-
DOI 10.1002/ana.410330605
-
Vecht, C. J. et al. Treatment of single brain metastasis: radiotherapy alone or combined with neurosurgery? Ann. Neurol. 33, 583-590 (1993). (Pubitemid 23161878)
-
(1993)
Annals of Neurology
, vol.33
, Issue.6
, pp. 583-590
-
-
Vecht, C.J.1
Haaxma-Reiche, H.2
Noordijk, E.M.3
Padberg, G.W.4
Voormolen, J.H.C.5
Hoekstra, F.H.6
Tans, J.T.J.7
Lambooij, N.8
Metsaars, J.A.L.9
Wattendorff, A.R.10
Brand, R.11
Hermans, J.12
-
13
-
-
2442713678
-
Whole brain radiation therapy with or without stereotactic radiosurgery boost for patients with one to three brain metastases: Phase III results of the RTOG 9508 randomised trial
-
DOI 10.1016/S0140-6736(04)16250-8, PII S0140673604162508
-
Andrews, D. W. et al. Whole brain radiation therapy with or without stereotactic radiosurgery boost for patients with one to three brain metastases: phase III results of the RTOG 9508 randomised trial. Lancet 363, 1665-1672 (2004). (Pubitemid 38670323)
-
(2004)
Lancet
, vol.363
, Issue.9422
, pp. 1665-1672
-
-
Andrews, D.W.1
Scott, C.B.2
Sperduto, P.W.3
Flanders, A.E.4
Gaspar, L.E.5
Schell, M.C.6
Werner-Wasik, M.7
Demas, W.8
Ryu, J.9
Bahary, J.-P.10
Souhami, L.11
Rotman, M.12
Mehta, M.P.13
Curran Jr., W.J.14
-
14
-
-
33744954692
-
Stereotactic radiosurgery plus whole-brain radiation therapy vs stereotactic radiosurgery alone for treatment of brain metastases: A randomized controlled trial
-
DOI 10.1001/jama.295.21.2483
-
Aoyama, H. et al. Stereotactic radiosurgery plus whole-brain radiation therapy vs stereotactic radiosurgery alone for treatment of brain metastases: a randomized controlled trial. JAMA 295, 2483-2491 (2006). (Pubitemid 43854963)
-
(2006)
Journal of the American Medical Association
, vol.295
, Issue.21
, pp. 2483-2491
-
-
Aoyama, H.1
Shirato, H.2
Tago, M.3
Nakagawa, K.4
Toyoda, T.5
Hatano, K.6
Kenjyo, M.7
Oya, N.8
Hirota, S.9
Shioura, H.10
Kunieda, E.11
Inomata, T.12
Hayakawa, K.13
Katoh, N.14
Kobashi, G.15
-
15
-
-
79951966253
-
Adjuvant whole-brain radiotherapy versus observation after radiosurgery or surgical resection of one to three cerebral metastases: Results of the EORTC 22952-26001 study
-
Kocher, M. et al. Adjuvant whole-brain radiotherapy versus observation after radiosurgery or surgical resection of one to three cerebral metastases: results of the EORTC 22952-26001 study. J. Clin. Oncol. 29, 134-141 (2011).
-
(2011)
J. Clin. Oncol.
, vol.29
, pp. 134-141
-
-
Kocher, M.1
-
16
-
-
0036731532
-
Phase II randomized trial of temozolomide and concurrent radiotherapy in patients with brain metastases
-
DOI 10.1200/JCO.2002.04.140
-
Antonadou, D. et al. Phase II randomized trial of temozolomide and concurrent radiotherapy in patients with brain metastases. J. Clin. Oncol. 20, 3644-3650 (2002). (Pubitemid 34983224)
-
(2002)
Journal of Clinical Oncology
, vol.20
, Issue.17
, pp. 3644-3650
-
-
Antonadou, D.1
Paraskevaidis, M.2
Sarris, G.3
Coliarakis, N.4
Economou, I.5
Karageorgis, P.6
Throuvalas, N.7
-
17
-
-
0035137984
-
Results of a phase III study of early versus delayed whole brain radiotherapy with concurrent cisplatin and vinorelbine combination in inoperable brain metastasis of non-small-cell lung cancer: Groupe Français de Pneumo-Cancérologie (GFPC) protocol 95-1
-
DOI 10.1023/A:1008338312647
-
Robinet, G. et al. Results of a phase III study of early versus delayed whole brain radiotherapy with concurrent cisplatin and vinorelbine combination in inoperable brain metastasis of non-small-cell lung cancer: Groupe Francais de Pneumo-Cancerologie (GFPC) Protocol 95-1. Ann. Oncol. 12, 59-67 (2001). (Pubitemid 32162449)
-
(2001)
Annals of Oncology
, vol.12
, Issue.1
, pp. 59-67
-
-
Robinet, G.1
Thomas, P.2
Breton, J.L.3
Lena, H.4
Gouva, S.5
Dabouis, G.6
Bennouna, J.7
Souquet, P.J.8
Balmes, P.9
Thiberville, L.10
Fournel, P.11
Quoix, E.12
Riou, R.13
Rebattu, P.14
Perol, M.15
Paillotin, D.16
Mornex, F.17
-
18
-
-
11144350196
-
Temozolomide and concomitant whole brain radiotherapy in patients with brain metastases: A phase II randomized trial
-
DOI 10.1016/j.ijrobp.2004.04.061, PII S0360301604007667
-
Verger, E. et al. Temozolomide and concomitant whole brain radiotherapy in patients with brain metastases: a phase II randomized trial. Int. J. Radiat. Oncol. Biol. Phys. 61, 185-191 (2005). (Pubitemid 40039121)
-
(2005)
International Journal of Radiation Oncology Biology Physics
, vol.61
, Issue.1
, pp. 185-191
-
-
Verger, E.1
Gil, M.2
Yaya, R.3
Vinolas, N.4
Villa, S.5
Pujol, T.6
Quinto, L.7
Graus, F.8
-
19
-
-
77955015464
-
AACR centennial series: The biology of cancer metastasis: Historical perspective
-
Talmadge, J. E. & Fidler, I. J. AACR centennial series: the biology of cancer metastasis: historical perspective. Cancer Res. 70, 5649-5669 (2010).
-
(2010)
Cancer Res.
, vol.70
, pp. 5649-5669
-
-
Talmadge, J.E.1
Fidler, I.J.2
-
20
-
-
33645834966
-
Metastatic patterns in adenocarcinoma
-
Hess, K. R. et al. Metastatic patterns in adenocarcinoma. Cancer 106, 1624-33 (2006).
-
(2006)
Cancer
, vol.106
, pp. 1624-1633
-
-
Hess, K.R.1
-
21
-
-
0018102908
-
Metastatic pattern of malignant melanoma. A study of 216 autopsy cases
-
Patel, J. K., Didolkar, M. S., Pickren, J. W. & Moore, R. H. Metastatic pattern of malignant melanoma. A study of 216 autopsy cases. Am. J. Surg. 135, 807-10 (1978). (Pubitemid 8377329)
-
(1978)
American Journal of Surgery
, vol.135
, Issue.6
, pp. 807-810
-
-
Patel, J.K.1
Didolkar, M.S.2
Pickren, J.W.3
Moore, R.H.4
-
22
-
-
50549121134
-
The distribution of secondary growths in cancer of the breast
-
Paget, S. The distribution of secondary growths in cancer of the breast. Lancet 133, 571-573 (1889).
-
(1889)
Lancet
, vol.133
, pp. 571-573
-
-
Paget, S.1
-
24
-
-
78650739435
-
Malignant cells facilitate lung metastasis by bringing their own soil
-
Duda, D. G. et al. Malignant cells facilitate lung metastasis by bringing their own soil. Proc. Natl Acad. Sci. USA 107, 21677-21682 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 21677-21682
-
-
Duda, D.G.1
-
25
-
-
73849129203
-
Real-time imaging reveals the single steps of brain metastasis formation
-
Kienast, Y. et al. Real-time imaging reveals the single steps of brain metastasis formation. Nat. Med. 16, 116-122 (2010).
-
(2010)
Nat. Med.
, vol.16
, pp. 116-122
-
-
Kienast, Y.1
-
26
-
-
77953215400
-
Capturing changes in the brain microenvironment during initial steps of breast cancer brain metastasis
-
Lorger, M. & Felding-Habermann, B. Capturing changes in the brain microenvironment during initial steps of breast cancer brain metastasis. Am. J. Pathol. 176, 2958-2971 (2010).
-
(2010)
Am. J. Pathol.
, vol.176
, pp. 2958-2971
-
-
Lorger, M.1
Felding-Habermann, B.2
-
27
-
-
67649240336
-
The vascular basement membrane as "soil" in brain metastasis
-
Carbonell, W. S., Ansorge, O., Sibson, N. & Muschel, R. The vascular basement membrane as "soil" in brain metastasis. PLoS ONE 4, e5857 (2009).
-
(2009)
PLoS ONE
, vol.4
-
-
Carbonell, W.S.1
Ansorge, O.2
Sibson, N.3
Muschel, R.4
-
28
-
-
53949093698
-
Reactive glia are recruited by highly proliferative brain metastases of breast cancer and promote tumor cell colonization
-
Fitzgerald, D. P. et al. Reactive glia are recruited by highly proliferative brain metastases of breast cancer and promote tumor cell colonization. Clin. Exp. Metastasis 25, 799-810 (2008).
-
(2008)
Clin. Exp. Metastasis
, vol.25
, pp. 799-810
-
-
Fitzgerald, D.P.1
-
29
-
-
0028856184
-
Reactions of astrocytes and microglial cells around hematogenous metastases of the human brain. Expression of endothelin-like immunoreactivity in reactive astrocytes and activation of microglial cells
-
Zhang, M. & Olsson, Y. Reactions of astrocytes and microglial cells around hematogenous metastases of the human brain. Expression of endothelin-like immunoreactivity in reactive astrocytes and activation of microglial cells. J. Neurol. Sci. 134, 26-32 (1995).
-
(1995)
J. Neurol. Sci.
, vol.134
, pp. 26-32
-
-
Zhang, M.1
Olsson, Y.2
-
30
-
-
63049104211
-
Microenvironmental regulation of metastasis
-
Joyce, J. A. & Pollard, J. W. Microenvironmental regulation of metastasis. Nat. Rev. Cancer 9, 239-252 (2009).
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 239-252
-
-
Joyce, J.A.1
Pollard, J.W.2
-
31
-
-
77956603258
-
Microglia promote colonization of brain tissue by breast cancer cells in a wnt-dependent way
-
Pukrop, T. et al. Microglia promote colonization of brain tissue by breast cancer cells in a Wnt-dependent way. Glia 58, 1477-1489 (2010).
-
(2010)
Glia
, vol.58
, pp. 1477-1489
-
-
Pukrop, T.1
-
32
-
-
33750480232
-
Differential reactions of microglia to brain metastasis of lung cancer
-
DOI 10.2119/2006-00033.He
-
He, B. P. et al. Differential reactions of microglia to brain metastasis of lung cancer. Mol. Med. 12, 161-170 (2006). (Pubitemid 44646345)
-
(2006)
Molecular Medicine
, vol.12
, Issue.7-8
, pp. 161-170
-
-
He, B.P.1
Wang, J.J.2
Zhang, X.3
Wu, Y.4
Wang, M.5
Bay, B.-H.6
Chang, A.Y.-C.7
-
33
-
-
79952073192
-
The role of the organ microenvironment in brain metastasis
-
Fidler, I. J. The role of the organ microenvironment in brain metastasis. Semin. Cancer Biol. 21, 107-112 (2011).
-
(2011)
Semin. Cancer Biol.
, vol.21
, pp. 107-112
-
-
Fidler, I.J.1
-
34
-
-
70449384375
-
Generation of an immortalized astrocyte cell line from H-2Kb-tsA58 mice to study the role of astrocytes in brain metastasis
-
Langley, R. R. et al. Generation of an immortalized astrocyte cell line from H-2Kb-tsA58 mice to study the role of astrocytes in brain metastasis. Int. J. Oncol. 35, 665-672 (2009).
-
(2009)
Int. J. Oncol.
, vol.35
, pp. 665-672
-
-
Langley, R.R.1
-
35
-
-
77956855574
-
Reactive astrocytes protect melanoma cells from chemotherapy by sequestering intracellular calcium through gap junction communication channels
-
Lin, Q. et al. Reactive astrocytes protect melanoma cells from chemotherapy by sequestering intracellular calcium through gap junction communication channels. Neoplasia 12, 748-754 (2010).
-
(2010)
Neoplasia
, vol.12
, pp. 748-754
-
-
Lin, Q.1
-
36
-
-
79952371255
-
Astrocytes upregulate survival genes in tumor cells and induce protection from chemotherapy
-
Kim, S. J. et al. Astrocytes upregulate survival genes in tumor cells and induce protection from chemotherapy Neoplasia 13, 286-298 (2011).
-
(2011)
Neoplasia
, vol.13
, pp. 286-298
-
-
Kim, S.J.1
-
37
-
-
79951672873
-
Interaction between lung cancer cells and astrocytes via specific inflammatory cytokines in the microenvironment of brain metastasis
-
Seike, T. et al. Interaction between lung cancer cells and astrocytes via specific inflammatory cytokines in the microenvironment of brain metastasis. Clin. Exp. Metastasis 28, 13-25 (2010).
-
(2010)
Clin. Exp. Metastasis
, vol.28
, pp. 13-25
-
-
Seike, T.1
-
38
-
-
1842536368
-
Brain metastases in melanoma: Roles of neurotrophins
-
DOI 10.1215/S115285170300067X
-
Denkins, Y. et al. Brain metastases in melanoma: roles of neurotrophins. Neuro Oncol. 6, 154-165 (2004). (Pubitemid 38455762)
-
(2004)
Neuro-Oncology
, vol.6
, Issue.2
, pp. 154-165
-
-
Denkins, Y.1
Reiland, J.2
Roy, M.3
Sinnappah-Kang, N.4
Galjour, J.5
Murry, B.P.6
Blust, J.7
Aucoin, R.8
Marchetti, D.9
-
39
-
-
0028945672
-
The role of trophic factors and autocrine/paracrine growth factors in brain metastasis
-
Menter, D. G., Herrmann, J. L. & Nicolson, G. L. The role of trophic factors and autocrine/paracrine growth factors in brain metastasis. Clin. Exp. Metastasis 13, 67-88 (1995).
-
(1995)
Clin. Exp. Metastasis
, vol.13
, pp. 67-88
-
-
Menter, D.G.1
Herrmann, J.L.2
Nicolson, G.L.3
-
40
-
-
0034648765
-
Angiogenesis in cancer and other diseases
-
Carmeliet, P. & Jain, R. K. Angiogenesis in cancer and other diseases. Nature 407, 249-257 (2000).
-
(2000)
Nature
, vol.407
, pp. 249-257
-
-
Carmeliet, P.1
Jain, R.K.2
-
41
-
-
33947732977
-
Angiogenesis: An organizing principle for drug discovery?
-
DOI 10.1038/nrd2115, PII NRD2115
-
Folkman, J. Angiogenesis: an organizing principle for drug discovery? Nat. Rev. Drug Discov. 6, 273-286 (2007). (Pubitemid 46505878)
-
(2007)
Nature Reviews Drug Discovery
, vol.6
, Issue.4
, pp. 273-286
-
-
Folkman, J.1
-
42
-
-
79956328903
-
Molecular mechanisms and clinical applications of angiogenesis
-
(in press)
-
Carmeliet, P. & Jain, R. K. Molecular mechanisms and clinical applications of angiogenesis. Nature (in press).
-
Nature
-
-
Carmeliet, P.1
Jain, R.K.2
-
43
-
-
34447632643
-
Angiogenesis in brain tumours
-
DOI 10.1038/nrn2175, PII NRN2175
-
Jain, R. K. et al. Angiogenesis in brain tumours. Nat. Rev. Neurosci. 8, 610-622 (2007). (Pubitemid 47093931)
-
(2007)
Nature Reviews Neuroscience
, vol.8
, Issue.8
, pp. 610-622
-
-
Jain, R.K.1
Di Tomaso, E.2
Duda, D.G.3
Loeffler, J.S.4
Sorensen, A.G.5
Batchelor, T.T.6
-
44
-
-
78650153633
-
Tumour vascularization via endothelial differentiation of glioblastoma stemlike cells
-
Ricci-Vitiani, L. et al. Tumour vascularization via endothelial differentiation of glioblastoma stemlike cells. Nature 468, 824-828 (2010).
-
(2010)
Nature
, vol.468
, pp. 824-828
-
-
Ricci-Vitiani, L.1
-
45
-
-
78650098659
-
Glioblastoma stem-like cells give rise to tumour endothelium
-
Wang, R. et al. Glioblastoma stem-like cells give rise to tumour endothelium. Nature 468, 829-833 (2010).
-
(2010)
Nature
, vol.468
, pp. 829-833
-
-
Wang, R.1
-
46
-
-
78651408563
-
Glioblastoma recurrence after cediranib therapy in patients: Lack of "rebound" revascularization as mode of escape
-
Di Tomaso, E. et al. Glioblastoma recurrence after cediranib therapy in patients: lack of "rebound" revascularization as mode of escape. Cancer Res. 71, 19-28 (2011).
-
(2011)
Cancer Res.
, vol.71
, pp. 19-28
-
-
Di Tomaso, E.1
-
47
-
-
79952721477
-
Transdifferentiation of glioblastoma cells into vascular endothelial cells
-
Soda, Y. et al. Transdifferentiation of glioblastoma cells into vascular endothelial cells. Proc. Natl Acad. Sci. USA 108, 4274-4280 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 4274-4280
-
-
Soda, Y.1
-
48
-
-
0037081299
-
165 induces progression of melanoma brain metastases without induction of sprouting angiogenesis
-
165 induces progression of melanoma brain metastases without induction of sprouting angiogenesis. Cancer Res. 62, 341-345 (2002). (Pubitemid 34106399)
-
(2002)
Cancer Research
, vol.62
, Issue.2
, pp. 341-345
-
-
Kusters, B.1
Leenders, W.P.J.2
Wesseling, P.3
Smits, D.4
Verrijp, K.5
Ruiter, D.J.6
Peters, J.P.W.7
Van Der Kogel, A.J.8
De Waal, R.M.W.9
-
49
-
-
4644304024
-
Antiangiogenic therapy of cerebral melanoma metastases results in sustained tumor progression via vessel co-option
-
DOI 10.1158/1078-0432.CCR-04-0823
-
Leenders, W. P. et al. Antiangiogenic therapy of cerebral melanoma metastases results in sustained tumor progression via vessel co-option. Clin. Cancer Res. 10, 6222-6230 (2004). (Pubitemid 39287530)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.18
, pp. 6222-6230
-
-
Leenders, W.P.J.1
Kusters, B.2
Verrijp, K.3
Maass, C.4
Wesseling, P.5
Heerschap, A.6
Ruiter, D.7
Ryan, A.8
De Waal, R.9
-
50
-
-
0036161382
-
The seed and soil hypothesis: Vascularisation and brain metastases
-
DOI 10.1016/S1470-2045(01)00622-2
-
Fidler, I. J., Yano, S., Zhang, R. D., Fujimaki, T. & Bucana, C. D. The seed and soil hypothesis: vascularisation and brain metastases. Lancet Oncol. 3, 53-57 (2002). (Pubitemid 34121146)
-
(2002)
Lancet Oncology
, vol.3
, Issue.1
, pp. 53-57
-
-
Fidler, I.J.1
Yano, S.2
Zhang, R.-D.3
Fujimaki, T.4
Bucana, C.D.5
-
51
-
-
0034282780
-
Expression of vascular endothelial growth factor is necessary but not sufficient for production and growth of brain metastasis
-
Yano, S. et al. Expression of vascular endothelial growth factor is necessary but not sufficient for production and growth of brain metastasis. Cancer Res. 60, 4959-4967 (2000).
-
(2000)
Cancer Res.
, vol.60
, pp. 4959-4967
-
-
Yano, S.1
-
52
-
-
3342959040
-
Vascular endothelial growth factor expression promotes the growth of breast cancer brain metastases in nude mice
-
DOI 10.1023/B:CLIN.0000024761.00373.55
-
Kim, L. S., Huang, S., Lu, W., Lev, D. C. & Price, J. E. Vascular endothelial growth factor expression promotes the growth of breast cancer brain metastases in nude mice. Clin. Exp. Metastasis 21, 107-118 (2004). (Pubitemid 38988084)
-
(2004)
Clinical and Experimental Metastasis
, vol.21
, Issue.2
, pp. 107-118
-
-
Lee, S.K.1
Huang, S.2
Lu, W.3
Lev, D.C.4
Price, J.E.5
-
53
-
-
67349264881
-
Noninvasive imaging of the functional effects of anti-VEGF therapy on tumor cell extravasation and regional blood volume in an experimental brain metastasis model
-
JuanYin, J. et al. Noninvasive imaging of the functional effects of anti-VEGF therapy on tumor cell extravasation and regional blood volume in an experimental brain metastasis model. Clin. Exp. Metastasis 26, 403-414 (2009).
-
(2009)
Clin. Exp. Metastasis
, vol.26
, pp. 403-414
-
-
JuanYin, J.1
-
55
-
-
78651109040
-
C-X-C receptor type 4 promotes metastasis by activating p38 mitogen-activated protein kinase in myeloid differentiation antigen (Gr-1)-positive cells
-
Hiratsuka, S. et al. C-X-C receptor type 4 promotes metastasis by activating p38 mitogen-activated protein kinase in myeloid differentiation antigen (Gr-1)-positive cells. Proc. Natl Acad. Sci. USA 108, 302-307 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 302-307
-
-
Hiratsuka, S.1
-
56
-
-
25144506525
-
Vessel tortuosity and brain tumor malignancy: A blinded study
-
DOI 10.1016/j.acra.2005.05.027, PII S1076633205005647
-
Bullitt, E. et al. Vessel tortuosity and brain tumor malignancy: a blinded study. Acad. Radiol. 12, 1232-1240 (2005). (Pubitemid 41354249)
-
(2005)
Academic Radiology
, vol.12
, Issue.10
, pp. 1232-1240
-
-
Bullitt, E.1
Zeng, D.2
Gerig, G.3
Aylward, S.4
Joshi, S.5
Smith, J.K.6
Lin, W.7
Ewend, M.G.8
-
57
-
-
0001633531
-
The endothelial hyperplasia of the cerebral blood vessels with brain tumors, and its sarcomatous transformation
-
Feigin, I., Allen, L. B., Lipkin, L. & Gross, S. W. The endothelial hyperplasia of the cerebral blood vessels with brain tumors, and its sarcomatous transformation. Cancer 11, 264-277 (1958).
-
(1958)
Cancer
, vol.11
, pp. 264-277
-
-
Feigin, I.1
Allen, L.B.2
Lipkin, L.3
Gross, S.W.4
-
58
-
-
0028025011
-
Vascular permeability and microcirculation of gliomas and mammary carcinomas transplanted in rat and mouse cranial windows
-
Yuan, F. et al. Vascular permeability and microcirculation of gliomas and mammary carcinomas transplanted in rat and mouse cranial windows. Cancer Res. 54, 4564-4568 (1994). (Pubitemid 24276471)
-
(1994)
Cancer Research
, vol.54
, Issue.17
, pp. 4564-4568
-
-
Yuan, F.1
Salehi, H.A.2
Boucher, Y.3
Vasthare, U.S.4
Tuma, R.F.5
Jain, R.K.6
-
59
-
-
79952756887
-
Endothelial focal adhesion kinase mediates cancer cell homing to discrete regions of the lungs via E-selectin upregulation
-
Hiratsuka, S. et al. Endothelial focal adhesion kinase mediates cancer cell homing to discrete regions of the lungs via E-selectin upregulation. Proc. Natl Acad. Sci. USA 108, 3725-3730 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 3725-3730
-
-
Hiratsuka, S.1
-
60
-
-
11844254414
-
Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
-
DOI 10.1126/science.1104819
-
Jain, R. K. Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science 307, 58-62 (2005). (Pubitemid 40093472)
-
(2005)
Science
, vol.307
, Issue.5706
, pp. 58-62
-
-
Jain, R.K.1
-
61
-
-
77950279550
-
Tumor microvasculature and microenvironment: Novel insights through intravital imaging in pre-clinical models
-
Fukumura, D., Duda, D. G., Munn, L. L. & Jain, R. K. Tumor microvasculature and microenvironment: novel insights through intravital imaging in pre-clinical models. Microcirculation 17, 206-225 (2010).
-
(2010)
Microcirculation
, vol.17
, pp. 206-225
-
-
Fukumura, D.1
Duda, D.G.2
Munn, L.L.3
Jain, R.K.4
-
62
-
-
27644534177
-
Rodent models of brain metastasis in melanoma
-
DOI 10.1097/00008390-200510000-00002
-
Cranmer, L. D., Trevor, K. T, Bandlamuri, S. & Hersh, E. M. Rodent models of brain metastasis in melanoma. Melanoma Res. 15, 325-356 (2005). (Pubitemid 41558944)
-
(2005)
Melanoma Research
, vol.15
, Issue.5
, pp. 325-356
-
-
Cranmer, L.D.1
Trevor, K.T.2
Bandlamuri, S.3
Hersh, E.M.4
-
63
-
-
49649109964
-
Development of a preclinical model of spontaneous human melanoma central nervous system metastasis
-
Cruz-Munoz, W., Man, S., Xu, P & Kerbel, R. S. Development of a preclinical model of spontaneous human melanoma central nervous system metastasis. Cancer Res. 68, 4500-4505 (2008).
-
(2008)
Cancer Res.
, vol.68
, pp. 4500-4505
-
-
Cruz-Munoz, W.1
Man, S.2
Xu, P.3
Kerbel, R.S.4
-
64
-
-
4944242194
-
Development of a chemoresistant orthotopic human nonsmall cell lung carcinoma model in nude mice: Analyses of tumor heterogeneity in relation to the immunohistochemical levels of expression of cyclooxygenase-2, ornithine decarboxylase, lung-related resistance protein, prostaglandin E synthetase, and glutathione-S-transferase (GST)-α, GST-μ, and GST-π
-
DOI 10.1002/cncr.20571
-
Mathieu, A. et al. Development of a chemoresistant orthotopic human nonsmall cel lung carcinoma model in nude mice: analyses of tumor heterogenity in relation to the immunohistochemical levels of expression of cyclooxygenase-2, ornithine decarboxylase, lung-related resistance protein, prostaglandin E synthetase, and glutathione-S-transferase-alpha (GST)-α, GST-μ, and GST-it. Cancer 101, 1908-1918 (2004). (Pubitemid 39328201)
-
(2004)
Cancer
, vol.101
, Issue.8
, pp. 1908-1918
-
-
Mathieu, A.1
Remmelink, M.2
D'Haene, N.3
Penant, S.4
Gaussin, J.-F.5
Van Ginckel, R.6
Darro, F.7
Kiss, R.8
Salmon, I.9
-
65
-
-
33847755430
-
Adaptation of energy metabolism in breast cancer brain metastases
-
DOI 10.1158/0008-5472.CAN-06-3137
-
Chen, E. I. et al. Adaptation of energy metabolism in breast cancer brain metastases. Cancer Res. 67, 1472-1486 (2007). (Pubitemid 46383371)
-
(2007)
Cancer Research
, vol.67
, Issue.4
, pp. 1472-1486
-
-
Chen, E.I.1
Hewel, J.2
Krueger, J.S.3
Tiraby, C.4
Weber, M.R.5
Kralli, A.6
Becker, K.7
Yates III, J.R.8
Felding-Habermann, B.9
-
66
-
-
0036554830
-
Role of host microenvironment in angiogenesis and microvascular functions in human breast cancer xenografts: Mammary fat pad versus cranial tumors
-
Monsky, W. L. et al. Role of host microenvironment in angiogenesis and microvascular functions in human breast cancer xenografts: mammary fat pad versus cranial tumors. Clin. Cancer Res. 8, 1008-1013 (2002). (Pubitemid 35177349)
-
(2002)
Clinical Cancer Research
, vol.8
, Issue.4
, pp. 1008-1013
-
-
Monsky, W.L.1
Carreira, C.M.2
Tsuzuki, Y.3
Gohongi, T.4
Fukumura, D.5
Jain, R.K.6
-
67
-
-
0029986283
-
Metastasis from human breast cancer cell lines
-
DOI 10.1007/BF01806081
-
Price, J. E. Metastasis from human breast cancer cell lines. Breast Cancer Res. Treat. 39, 93-102 (1996). (Pubitemid 26136507)
-
(1996)
Breast Cancer Research and Treatment
, vol.39
, Issue.1
, pp. 93-102
-
-
Price, J.E.1
-
68
-
-
0025192243
-
Tumorigenicity and metastatis of human breast carcinoma cell lines in nude mice
-
Price, J. E., Polyzos, A., Zhang, R. D. & Daniels, L. M. Tumorigenicity and metastasis of human breast carcinoma cell lines in nude mice. Cancer Res. 50, 717-721 (1990). (Pubitemid 20054204)
-
(1990)
Cancer Research
, vol.50
, Issue.3
, pp. 717-721
-
-
Price, J.E.1
Polyzos, A.2
Zhang, R.D.3
Daniels, L.M.4
-
69
-
-
0029851043
-
Brain metastasis model in athymic nude mice using a novel MUC1-secreting human breast-cancer cell line, MA11
-
DOI 10.1002/(SICI)1097-0215(19961127)68:5<682::AID-IJC20>3.0.CO;2-2
-
Rye, P D. et al. Brain metastasis model in athymic nude mice using a novel MUC1-secreting human breast-cancer cell line, MA11. Int J. Cancer 68, 682-687 (1996). (Pubitemid 26414532)
-
(1996)
International Journal of Cancer
, vol.68
, Issue.5
, pp. 682-687
-
-
Rye, P.D.1
Norum, L.2
Olsen, D.-R.3
Garman-Vik, S.4
Kaul, S.5
Fodstad, O.6
-
70
-
-
0034912833
-
A bone-seeking clone exhibits different biological properties from the MDA-MB-231 parental human breast cancer cells and a brain-seeking clone in vivo and in vitro
-
Yoneda, T, Williams, P J., Hiraga, T, Niewolna, M. & Nishimura, R. A bone-seeking clone exhibits different biological properties from the MDA-MB-231 parental human breast cancer cells and a brain-seeking clone in vivo and in vitro. J. Bone Miner. Res. 16, 1486-1495 (2001). (Pubitemid 32675200)
-
(2001)
Journal of Bone and Mineral Research
, vol.16
, Issue.8
, pp. 1486-1495
-
-
Yoneda, T.1
Williams, P.J.2
Hiraga, T.3
Niewolna, M.4
Nishimura, R.5
-
71
-
-
0026351389
-
Relative malignant potential of human breast carcinoma cell lines established from pleural effusions and a brain metastasis
-
Zhang, R. D., Fidler, I. J. & Price, J. E. Relative malignant potential of human breast carcinoma cell lines established from pleural effusions and a brain metastasis. Invasion Metastasis 11, 204-215 (1991).
-
(1991)
Invasion Metastasis
, vol.11
, pp. 204-215
-
-
Zhang, R.D.1
Fidler, I.J.2
Price, J.E.3
-
72
-
-
0033368578
-
The biology of melanoma brain metastasis
-
DOI 10.1023/A:1006329410433
-
Fidler, I. J., Schackert, G., Zhang, R. D., Radinsky, R. & Fujimaki, T. The biology of melanoma brain metastasis. Cancer Metastasis Rev. 18, 387-400 (1999). (Pubitemid 30104071)
-
(1999)
Cancer and Metastasis Reviews
, vol.18
, Issue.3
, pp. 387-400
-
-
Fidler, I.J.1
Schackert, G.2
Zhang, R.-D.3
Radinsky, R.4
Fujimaki, T.5
-
73
-
-
34249317254
-
Her-2 overexpression increases the metastatic outgrowth of breast cancer cells in the brain
-
DOI 10.1158/0008-5472.CAN-06-3316
-
Palmieri, D. et al. HER-2 overexpression increases the metastatic outgrowth of breast cancer cells in the brain. Cancer Res. 67, 4190-4198 (2007). (Pubitemid 46815065)
-
(2007)
Cancer Research
, vol.67
, Issue.9
, pp. 4190-4198
-
-
Palmieri, D.1
Bronder, J.L.2
Herring, J.M.3
Yoneda, T.4
Weil, R.J.5
Stark, A.M.6
Kurek, R.7
Vega-Valle, E.8
Feigenbaum, L.9
Halverson, D.10
Vortmeyer, A.O.11
Steinberg, S.M.12
Aldape, K.13
Steeg, P.S.14
-
74
-
-
49449112267
-
Effect of lapatinib on the outgrowth of metastatic breast cancer cells to the brain
-
Gril, B. et al. Effect of lapatinib on the outgrowth of metastatic breast cancer cells to the brain. J. Natl Cancer Inst. 100, 1092-1103 (2008).
-
(2008)
J. Natl Cancer Inst.
, vol.100
, pp. 1092-1103
-
-
Gril, B.1
-
75
-
-
0037149539
-
Herceptin acts as an anti-angiogenic cocktail
-
Izumi, Y., Xu, L., di Tomaso, E., Fukumura, D. & Jain, R. K. Tumour biology: herceptin acts as an anti-angiogenic cocktail. Nature 416, 279-280 (2002). (Pubitemid 34260234)
-
(2002)
Nature
, vol.416
, Issue.6878
, pp. 279-280
-
-
Izumi, Y.1
Xu, L.2
Di Tomaso, E.3
Fukumura, D.4
Jain, R.K.5
-
76
-
-
77954062987
-
Secreted gaussia luciferase as a biomarker for monitoring tumor progression and treatment response of systemic metastases
-
Chung, E. et al. Secreted Gaussia luciferase as a biomarker for monitoring tumor progression and treatment response of systemic metastases. PLoS ONE 4, e8316 (2009).
-
(2009)
PLoS ONE
, vol.4
-
-
Chung, E.1
-
77
-
-
0024503254
-
B16 melanoma spontaneous brain metastasis: Occurrence and development within leptomeninges blood vessels
-
DOI 10.1007/BF02057178
-
Alterman, A. L. & Stackpole, C. W. B16 melanoma spontaneous brain metastasis: occurrence and development within leptomeninges blood vessels. Clin. Exp. Metastasis 7, 15-23 (1989). (Pubitemid 19021785)
-
(1989)
Clinical and Experimental Metastasis
, vol.7
, Issue.1
, pp. 15-23
-
-
Alterman, A.L.1
Stackpole, C.W.2
-
78
-
-
67649300721
-
Genes that mediate breast cancer metastasis to the brain
-
Bos, P. D. et al. Genes that mediate breast cancer metastasis to the brain. Nature 459, 1005-1009 (2009).
-
(2009)
Nature
, vol.459
, pp. 1005-1009
-
-
Bos, P.D.1
-
79
-
-
78650378532
-
Heterogeneous blood-tumor barrier permeability determines drug efficacy in mouse brain metastases of breast cancer
-
Lockman, P. R. et al. Heterogeneous blood-tumor barrier permeability determines drug efficacy in mouse brain metastases of breast cancer. Clin. Cancer Res. 16, 5664-5678 (2010).
-
(2010)
Clin. Cancer Res.
, vol.16
, pp. 5664-5678
-
-
Lockman, P.R.1
-
80
-
-
0036359767
-
Scaling down imaging: Molecular mapping of cancer in mice
-
Weissleder, R. Scaling down imaging: molecular mapping of cancer in mice. Nat. Rev. Cancer 2, 11-18 (2002). (Pubitemid 37328803)
-
(2002)
Nature Reviews Cancer
, vol.2
, Issue.1
, pp. 11-18
-
-
Weissleder, R.1
-
81
-
-
41649110649
-
Imaging in the era of molecular oncology
-
DOI 10.1038/nature06917, PII NATURE06917
-
Weissleder, R. & Pittet, M. J. Imaging in the era of molecular oncology. Nature 452, 580-589 (2008). (Pubitemid 351483372)
-
(2008)
Nature
, vol.452
, Issue.7187
, pp. 580-589
-
-
Weissleder, R.1
Pittet, M.J.2
-
82
-
-
34249738489
-
MRI of mouse models of neurological disorders
-
DOI 10.1002/nbm.1167
-
Anderson, S. A. & Frank, J. A. MRI of mouse models of neurological disorders. NMR Biomed. 20, 200-215 (2007). (Pubitemid 46824527)
-
(2007)
NMR in Biomedicine
, vol.20
, Issue.3
, pp. 200-215
-
-
Anderson, S.A.1
Frank, J.A.2
-
83
-
-
11144349653
-
Methods for magnetically labeling stem and other cells for detection by in vivo magnetic resonance imaging
-
DOI 10.1080/14653240410005267
-
Frank, J. A. et al. Methods for magnetically labeling stem and other cells for detection by in vivo magnetic resonance imaging. Cytotherapy 6, 621-625 (2004). (Pubitemid 40028925)
-
(2004)
Cytotherapy
, vol.6
, Issue.6
, pp. 621-625
-
-
Frank, J.A.1
Anderson, S.A.2
Kalsih, H.3
Jordan, E.K.4
Lewis, B.K.5
Yocum, G.T.6
Arbab, A.S.7
-
84
-
-
33750624652
-
In vivo MRI of cancer cell fate at the single-cell level in a mouse model of breast cancer metastasis to the brain
-
DOI 10.1002/mrm.21029
-
Heyn, C. et al. In vivo MRI of cancer cell fate at the single-cell level in a mouse model of breast cancer metastasis to the brain. Magn. Reson. Med. 56, 1001-1010 (2006). (Pubitemid 44691342)
-
(2006)
Magnetic Resonance in Medicine
, vol.56
, Issue.5
, pp. 1001-1010
-
-
Heyn, C.1
Ronald, J.A.2
Ramadan, S.S.3
Snir, J.A.4
Barry, A.M.5
MacKenzie, L.T.6
Mikulis, D.J.7
Palmieri, D.8
Bronder, J.L.9
Steeg, P.S.10
Yoneda, T.11
MacDonald, I.C.12
Chambers, A.F.13
Rutt, B.K.14
Foster, P.J.15
-
85
-
-
79952648874
-
* imaging of metastatic human breast cancer to brain in the nude rat at 3 T
-
* imaging of metastatic human breast cancer to brain in the nude rat at 3 T. NMR Biomed. 24, 325-334 (2011).
-
(2011)
NMR Biomed.
, vol.24
, pp. 325-334
-
-
Song, H.T.1
-
86
-
-
71149107667
-
Rat model of metastatic breast cancer monitored by MRI at 3 tesla and bioluminescence imaging with histological correlation
-
Song, H. T. et al. Rat model of metastatic breast cancer monitored by MRI at 3 tesla and bioluminescence imaging with histological correlation. J. Transl. Med. 7, 88 (2009).
-
(2009)
J. Transl. Med.
, vol.7
, pp. 88
-
-
Song, H.T.1
-
87
-
-
29244463365
-
Astrocyte-endothelial interactions at the blood-brain barrier
-
DOI 10.1038/nrn1824
-
Abbott, N. J., Rönnbäck, L. & Hansson, E. Astrocyte-endothelial interactions at the blood-brain barrier. Nat. Rev. Neurosci. 7, 41-53 (2006). (Pubitemid 41828930)
-
(2006)
Nature Reviews Neuroscience
, vol.7
, Issue.1
, pp. 41-53
-
-
Abbott, N.J.1
Ronnback, L.2
Hansson, E.3
-
88
-
-
0348231898
-
Mechanisms of disease: The blood-brain barrier
-
Neuwelt, E. A. Mechanisms of disease: the blood-brain barrier. Neurosurgery 54, 131-140 (2004).
-
(2004)
Neurosurgery
, vol.54
, pp. 131-140
-
-
Neuwelt, E.A.1
-
89
-
-
34250177984
-
The blood-brain barrier and cancer: Transporters, treatment, and trojan horses
-
DOI 10.1158/1078-0432.CCR-06-2854
-
Deeken, J. F. & Loscher, W. The blood-brain barrier and cancer: transporters, treatment, and Trojan horses. Clin. Cancer Res. 13, 1663-1674 (2007). (Pubitemid 46952931)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.6
, pp. 1663-1674
-
-
Deeken, J.F.1
Loscher, W.2
-
90
-
-
0035881307
-
Hypoxia and acidosis independently up-regulate vascular endothelial growth factor transcription in brain tumors in vivo
-
Fukumura, D. et al. Hypoxia and acidosis independently up-regulate vascular endothelial growth factor transcription in brain tumors in vivo. Cancer Res. 61, 6020-6024 (2001). (Pubitemid 32762531)
-
(2001)
Cancer Research
, vol.61
, Issue.16
, pp. 6020-6024
-
-
Fukumura, D.1
Xu, L.2
Chen, Y.3
Gohongi, T.4
Seed, B.5
Jain, R.K.6
-
91
-
-
0032516078
-
Regulation of transport pathways in tumor vessels: Role of tumor type and microenvironment
-
DOI 10.1073/pnas.95.8.4607
-
Hobbs, S. K. et al. Regulation of transport pathways in tumor vessels: role of tumor type and microenvironment. Proc. Natl Acad. Sci. USA 95, 4607-4612 (1998). (Pubitemid 28207960)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.8
, pp. 4607-4612
-
-
Hobbs, S.K.1
Monsky, W.L.2
Yuan, F.3
Roberts, W.G.4
Griffith, L.5
Torchilin, V.P.6
Jain, R.K.7
-
92
-
-
0033567094
-
Augmentation of transvascular transport of macromolecules and nanoparticles in tumors using vascular endothelial growth factor
-
Monsky, W. L. et al. Augmentation of transvascular transport of macromolecules and nanoparticles in tumors using vascular endothelial growth factor. Cancer Res. 59, 4129-4135 (1999). (Pubitemid 29393588)
-
(1999)
Cancer Research
, vol.59
, Issue.16
, pp. 4129-4135
-
-
Monsky, W.L.1
Fukumura, D.2
Gohongi, T.3
Ancukiewcz, M.4
Weich, H.A.5
Torchilin, V.P.6
Yuan, F.7
Jain, R.K.8
-
93
-
-
0026440587
-
Differential permeability of the blood-brain barrier in experimental brain metastases produced by human neoplasms implanted into nude mice
-
Zhang, R. D., Price, J. E., Fujimaki, T., Bucana, C. D. & Fidler, I. J. Differential permeability of the blood-brain barrier in experimental brain metastases produced by human neoplasms implanted into nude mice. Am. J. Pathol. 141, 1115-1124 (1992).
-
(1992)
Am. J. Pathol.
, vol.141
, pp. 1115-1124
-
-
Zhang, R.D.1
Price, J.E.2
Fujimaki, T.3
Bucana, C.D.4
Fidler, I.J.5
-
94
-
-
0035692282
-
Multidrug resistance in brain tumors: Roles of the blood-brain barrier
-
DOI 10.1023/A:1013104423154
-
Regina, A. et al. Multidrug resistance in brain tumors: roles of the blood-brain barrier. Cancer Metastasis Rev. 20, 13-25 (2001). (Pubitemid 34074674)
-
(2001)
Cancer and Metastasis Reviews
, vol.20
, Issue.1-2
, pp. 13-25
-
-
Regina, A.1
Demeule, M.2
Laplante, A.3
Jodoin, J.4
Dagenais, C.5
Berthelet, F.6
Moghrabi, A.7
Beliveau, R.8
-
95
-
-
0032483685
-
Postoperative radiotherapy in the treatment of single metastases to the brain: A randomized trial
-
DOI 10.1001/jama.280.17.1485
-
Patchell, R. A. et al. Postoperative radiotherapy in the treatment of single metastases to the brain: a randomized trial. JAMA 280, 1485-1489 (1998). (Pubitemid 28507400)
-
(1998)
Journal of the American Medical Association
, vol.280
, Issue.17
, pp. 1485-1489
-
-
Patchell, R.A.1
Tibbs, P.A.2
Regine, W.F.3
Dempsey, R.J.4
Mohiuddin, M.5
Kryscio, R.J.6
Markesbery, W.R.7
Foon, K.A.8
Young, B.9
-
96
-
-
34347387938
-
Strategies to improve drug delivery across the blood-brain barrier
-
DOI 10.2165/00003088-200746070-00002
-
de Boer, A. G. & Gaillard, P. J. Strategies to improve drug delivery across the blood-brain barrier. Clin. Pharmacokinet. 46, 553-576 (2007). (Pubitemid 47025357)
-
(2007)
Clinical Pharmacokinetics
, vol.46
, Issue.7
, pp. 553-576
-
-
De Boer, A.G.1
Gaillard, P.J.2
-
97
-
-
50349092250
-
LDL receptor-related protein 1: Unique tissue-specific functions revealed by selective gene knockout studies
-
Lillis, A. P., Van Duyn, L. B., Murphy-Ullrich, J. E. & Strickland, D. K. LDL receptor-related protein 1: unique tissue-specific functions revealed by selective gene knockout studies. Physiol. Rev. 88, 887-918 (2008).
-
(2008)
Physiol. Rev.
, vol.88
, pp. 887-918
-
-
Lillis, A.P.1
Van Duyn, L.B.2
Murphy-Ullrich, J.E.3
Strickland, D.K.4
-
98
-
-
47749105642
-
Re-engineering biopharmaceuticals for delivery to brain with molecular Trojan horses
-
DOI 10.1021/bc800148t
-
Pardridge, W. M. Re-engineering biopharmaceuticals for delivery to brain with molecular Trojan horses. Bioconjug. Chem. 19, 1327-1338 (2008). (Pubitemid 352032329)
-
(2008)
Bioconjugate Chemistry
, vol.19
, Issue.7
, pp. 1327-1338
-
-
Pardridge, W.M.1
-
99
-
-
0028150689
-
Subcellular localization and endocytic function of low density lipoprotein receptor-related protein in human glioblastoma cells
-
Bu, G., Maksymovitch, E. A., Geuze, H. & Schwartz, A. L. Subcellular localization and endocytic function of low density lipoprotein receptor-related protein in human glioblastoma cells. J. Biol. Chem. 269, 29874-29882 (1994). (Pubitemid 24365153)
-
(1994)
Journal of Biological Chemistry
, vol.269
, Issue.47
, pp. 29874-29882
-
-
Bu, G.1
Maksymovitch, E.A.2
Geuze, H.3
Schwartz, A.L.4
-
100
-
-
18744415035
-
High transcytosis of melanotransferrin (P97) across the blood-brain barrier
-
DOI 10.1046/j.1471-4159.2002.01201.x
-
Demeule, M. et al. High transcytosis of melanotransferrin (P97) across the blood-brain barrier. J. Neurochem. 83, 924-933 (2002). (Pubitemid 35316043)
-
(2002)
Journal of Neurochemistry
, vol.83
, Issue.4
, pp. 924-933
-
-
Demeule, M.1
Poirier, J.2
Jodoin, J.3
Bertrand, Y.4
Desrosiers, R.R.5
Dagenais, C.6
Nguyen, T.7
Lanthier, J.8
Gabathuler, R.9
Kennard, M.10
Jefferies, W.A.11
Karkan, D.12
Tsai, S.13
Fenart, L.14
Cecchelli, R.15
Beliveau, R.16
-
101
-
-
8744266243
-
Efficient transfer of receptor-associated protein (RAP) across the blood-brain barrier
-
DOI 10.1242/jcs.01381
-
Pan, W. et al. Efficient transfer of receptor-associated protein (RAP) across the blood-brain barrier. J. Cell Sci. 117, 5071-5078 (2004). (Pubitemid 39517522)
-
(2004)
Journal of Cell Science
, vol.117
, Issue.21
, pp. 5071-5078
-
-
Pan, W.1
Kastin, A.B.2
Zankel, T.C.3
Van Kerkhof, P.4
Terasaki, T.5
Bu, G.6
-
102
-
-
79958041962
-
-
US National Library of Medicine [online]
-
US National Library of Medicine. Clinicaltrials.gov [online], http://clinicaltrials.gov/ct2/show/NCT00539383 (2010).
-
(2010)
-
-
-
103
-
-
79958038295
-
-
US National Library of Medicine [online]
-
US National Library of Medicine. Clinicaltrials.gov [online], http://clinicaltrials.gov/ct2/show/NCT00539344 (2010).
-
(2010)
-
-
-
104
-
-
51349102460
-
Antitumour activity of ANG1005, a conjugate between paclitaxel and the new brain delivery vector angiopep-2
-
Regina, A. et al. Antitumour activity of ANG1005, a conjugate between paclitaxel and the new brain delivery vector Angiopep-2. Br. J. Pharmacol. 155, 185-197 (2008).
-
(2008)
Br. J. Pharmacol.
, vol.155
, pp. 185-197
-
-
Regina, A.1
-
105
-
-
70350228485
-
Uptake of ANG1005, a novel paclitaxel derivative, through the blood-brain barrier into brain and experimental brain metastases of breast cancer
-
Thomas, F. C. et al. Uptake of ANG1005, a novel paclitaxel derivative, through the blood-brain barrier into brain and experimental brain metastases of breast cancer. Pharm. Res. 26, 2486-2494 (2009).
-
(2009)
Pharm. Res.
, vol.26
, pp. 2486-2494
-
-
Thomas, F.C.1
-
106
-
-
0024325795
-
The combined use of radiation therapy and lonidamine in the treatment of brain metastases
-
DeAngelis, L. M. et al. The combined use of radiation therapy and lonidamine in the treatment of brain metastases. J. Neurooncol. 7, 241-247 (1989). (Pubitemid 19225514)
-
(1989)
Journal of Neuro-Oncology
, vol.7
, Issue.3
, pp. 241-247
-
-
DeAngelis, L.M.1
Currie, V.E.2
Kim, J.-H.3
Krol, G.4
O'Hehir, M.A.5
Farag, F.M.6
Young, C.W.7
Posner, J.B.8
-
107
-
-
0021702452
-
Randomized trial of radiotherapy versus radiotherapy plus metronidazole for the treatment metastatic cancer to brain. A Southwest oncology group study
-
Eyre, H. J. et al. Randomized trial of radiotherapy versus radiotherapy plus metronidazole for the treatment metastatic cancer to brain. A Southwest Oncology Group study. J. Neurooncol. 2, 325-330 (1984). (Pubitemid 15191842)
-
(1984)
Journal of Neuro-Oncology
, vol.2
, Issue.4
, pp. 325-330
-
-
Eyre, H.J.1
Ohlsen, J.D.2
Frank, J.3
-
108
-
-
0025969535
-
A randomized phase III protocol for the evaluation of misonidazole combined with radiation in the treatment of patients with brain metastases (RTOG-7916)
-
Komarnicky, L. T. et al. A randomized phase III protocol for the evaluation of misonidazole combined with radiation in the treatment of patients with brain metastases (RTOG-7916). Int. J. Radiat. Oncol. Biol. Phys. 20, 53-58 (1991).
-
(1991)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.20
, pp. 53-58
-
-
Komarnicky, L.T.1
-
109
-
-
61549104698
-
Motexafin gadolinium combined with prompt whole brain radiotherapy prolongs time to neurologic progression in non-small-cell lung cancer patients with brain metastases: Results of a phase III trial
-
Mehta, M. P. et al. Motexafin gadolinium combined with prompt whole brain radiotherapy prolongs time to neurologic progression in non-small-cell lung cancer patients with brain metastases: results of a phase III trial. Int. J. Radiat. Oncol. Biol. Phys. 73, 1069-1076 (2009).
-
(2009)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.73
, pp. 1069-1076
-
-
Mehta, M.P.1
-
110
-
-
0029114147
-
Results of a randomized comparison of radiotherapy and bromodeoxyuridine with radiotherapy alone for brain metastases: Report of RTOG trial 89-05
-
Phillips, T. L., Scott, C. B., Leibel, S. A., Rotman, M. & Weigensberg, I. J. Results of a randomized comparison of radiotherapy and bromodeoxyuridine with radiotherapy alone for brain metastases: report of RTOG trial 89-05 Int. J. Radiat. Oncol. Biol. Phys. 33, 339-348 (1995).
-
(1995)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.33
, pp. 339-348
-
-
Phillips, T.L.1
Scott, C.B.2
Leibel, S.A.3
Rotman, M.4
Weigensberg, I.J.5
-
111
-
-
33644499236
-
Phase III study of efaproxiral as an adjunct to whole-brain radiation therapy for brain metastases
-
DOI 10.1200/JCO.2004.00.1768
-
Suh, J. H. et al. Phase III study of efaproxiral as an adjunct to whole-brain radiation therapy for brain metastases. J. Clin. Oncol. 24, 106-114 (2006). (Pubitemid 46630501)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.1
, pp. 106-114
-
-
Suh, J.H.1
Stea, B.2
Nabid, A.3
Kresl, J.J.4
Fortin, A.5
Mercier, J.-P.6
Senzer, N.7
Chang, E.L.8
Boyd, A.P.9
Cagnoni, P.J.10
Shaw, E.11
-
112
-
-
58749092817
-
A phase III trial of topotecan and whole brain radiation therapy for patients with CNS-metastases due to lung cancer
-
Neuhaus, T. et al. A phase III trial of topotecan and whole brain radiation therapy for patients with CNS-metastases due to lung cancer. Br. J. Cancer 100, 291-297 (2009).
-
(2009)
Br. J. Cancer
, vol.100
, pp. 291-297
-
-
Neuhaus, T.1
-
113
-
-
67649342903
-
Vorinostat enhances the radiosensitivity of a breast cancer brain metastatic cell line grown in vitro and as intracranial xenografts
-
Baschnagel, A. et al. Vorinostat enhances the radiosensitivity of a breast cancer brain metastatic cell line grown in vitro and as intracranial xenografts. Mol. Cancer Ther. 8, 1589-1595 (2009).
-
(2009)
Mol. Cancer Ther.
, vol.8
, pp. 1589-1595
-
-
Baschnagel, A.1
-
114
-
-
70349671463
-
Vorinostat inhibits brain metastatic colonization in a model of triple-negative breast cancer and induces DNA doublestrand breaks
-
Palmieri, D. et al. Vorinostat inhibits brain metastatic colonization in a model of triple-negative breast cancer and induces DNA doublestrand breaks. Clin. Cancer Res. 15, 6148-6157 (2009).
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 6148-6157
-
-
Palmieri, D.1
-
115
-
-
79958039315
-
-
US National Library of Medicine [online]
-
US National Library of Medicine. Clinicaltrials.gov [online], http://clinicaltrials.gov/ct2/show/NCT00838929 (2011).
-
(2011)
-
-
-
116
-
-
79958021617
-
-
US National Library of Medicine [online]
-
US National Library of Medicine. Clinicaltrials.gov [online], http://clinicaltrials.gov/ct2/show/NCT00946673 (2010).
-
(2010)
-
-
-
117
-
-
74949092481
-
Bevacizumab safety in patients with central nervous system metastases
-
Besse, B. et al. Bevacizumab safety in patients with central nervous system metastases. Clin. Cancer Res. 16, 269-278 (2010).
-
(2010)
Clin. Cancer Res.
, vol.16
, pp. 269-278
-
-
Besse, B.1
-
118
-
-
70449725036
-
Safety of bevacizumab in patients with non-small-cell lung cancer and brain metastases
-
Socinski, M. A. et al. Safety of bevacizumab in patients with non-small-cell lung cancer and brain metastases. J. Clin. Oncol. 27, 5255-5261 (2009).
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 5255-5261
-
-
Socinski, M.A.1
-
119
-
-
49749101701
-
Safety of bevacizumab (Bv) therapy in combination with chemotherapy in subjects with non-small cell lung cancer (NSCLC) treated on ATLAS [abstract]
-
Polikoff, J. et al. Safety of bevacizumab (Bv) therapy in combination with chemotherapy in subjects with non-small cell lung cancer (NSCLC) treated on ATLAS [abstract]. J. Clin. Oncol. 26 (15 Suppl.), a8079 (2008).
-
(2008)
J. Clin. Oncol.
, vol.26
, Issue.15 SUPPL.
-
-
Polikoff, J.1
-
120
-
-
78449266761
-
Efficacy and safety of bevacizumab in active brain metastases from non-small cell lung cancer
-
De Braganca, et al. Efficacy and safety of bevacizumab in active brain metastases from non-small cell lung cancer. J. Neurooncol. 100, 443-447 (2010).
-
(2010)
J. Neurooncol.
, vol.100
, pp. 443-447
-
-
De Braganca1
-
121
-
-
79958023367
-
A phase I study of cediranib plus whole-brain radiation therapy in patients with brain metastases from non-small cell lung cancer [abstract]
-
Eichler, A. F. et al. A phase I study of cediranib plus whole-brain radiation therapy in patients with brain metastases from non-small cell lung cancer [abstract]. J. Clin. Oncol. 28 (15 Suppl.), TPS177 (2010).
-
(2010)
J. Clin. Oncol.
, vol.28
, Issue.15 SUPPL.
-
-
Eichler, A.F.1
-
122
-
-
4143110253
-
Gefitinib in patients with brain metastasesfrom non-small-cell lung cancer: A prospective trial
-
DOI 10.1093/annonc/mdh276
-
Ceresoli, G. L. et al. Gefitinib in patients with brain metastases from non-small-cell lung cancer: a prospective trial. Ann. Oncol. 15, 1042-1047 (2004). (Pubitemid 39089780)
-
(2004)
Annals of Oncology
, vol.15
, Issue.7
, pp. 1042-1047
-
-
Ceresoli, G.L.1
Cappuzzo, F.2
Gregorc, V.3
Bartolini, S.4
Crino, L.5
Villa, E.6
-
123
-
-
34548049302
-
Gefitinib as palliative therapy for lung adenocarcinoma metastatic to the brain
-
DOI 10.1016/j.lungcan.2007.03.011, PII S0169500207001821
-
Wu, C. et al. Gefitinib as palliative therapy for lung adenocarcinoma metastatic to the brain. Lung Cancer 57, 359-364 (2007). (Pubitemid 47285416)
-
(2007)
Lung Cancer
, vol.57
, Issue.3
, pp. 359-364
-
-
Wu, C.1
Li, Y.L.2
Wang, Z.M.3
Li, Z.4
Zhang, T.X.5
Wei, Z.6
-
124
-
-
36849072644
-
Response of intracranial metastases to erlotinib therapy
-
DOI 10.1200/JCO.2007.13.3751
-
Fekrazad, M. H., Ravindranathan, M. & Jones, D. V. Jr. Response of intracranial metastases to erlotinib therapy. J. Clin. Oncol. 25, 5024-5026 (2007). (Pubitemid 350220437)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.31
, pp. 5024-5026
-
-
Fekrazad, M.H.1
Ravindranathan, M.2
Jones Jr., D.V.3
-
125
-
-
30844446711
-
Complete response to erlotinib treatment in brain metastases from recurrent NSCLC [1]
-
DOI 10.1136/thx.2005.052233
-
Lai, C. S., Boshoff, C., Falzon, M. & Lee, S. M. Complete response to erlotinib treatment in brain metastases from recurrent NSCLC. Thorax 61, 91 (2006). (Pubitemid 43106986)
-
(2006)
Thorax
, vol.61
, Issue.1
, pp. 91
-
-
Lai, C.S.L.1
Boshoff, C.2
Falzon, M.3
Lee, S.M.4
-
126
-
-
33847610070
-
Recurrent responses to non-small cell lung cancer brain metastases with erlotinib
-
DOI 10.1016/j.lungcan.2006.11.009, PII S0169500206006179
-
Popat, S. et al. Recurrent responses to non-small cell lung cancer brain metastases with erlotinib. Lung Cancer 56, 135-137 (2007). (Pubitemid 46356639)
-
(2007)
Lung Cancer
, vol.56
, Issue.1
, pp. 135-137
-
-
Popat, S.1
Hughes, S.2
Papadopoulos, P.3
Wilkins, A.4
Moore, S.5
Priest, K.6
Meehan, L.7
Norton, A.8
O'Brien, M.9
-
127
-
-
67849103953
-
Epidermal growth factor receptor tyrosine kinase inhibitors as a first-line therapy for never-smokers with adenocarcinoma of the lung having asymptomatic synchronous brain metastasis
-
Kim, J. E. et al. Epidermal growth factor receptor tyrosine kinase inhibitors as a first-line therapy for never-smokers with adenocarcinoma of the lung having asymptomatic synchronous brain metastasis. Lung Cancer 65, 351-354 (2009).
-
(2009)
Lung Cancer
, vol.65
, pp. 351-354
-
-
Kim, J.E.1
-
128
-
-
33645453677
-
Phase III study of gemcitabine and cisplatin with or without aprinocarsen, a protein kinase C-alpha antisense oligonucleotide, in patients with advanced-stage non-small-cell lung cancer
-
DOI 10.1200/JCO.2005.04.3299
-
Paz-Ares, L. et al. Phase III study of gemcitabine and cisplatin with or without aprinocarsen, a protein kinase C-alpha antisense oligonucleotide, in patients with advanced-stage non-small-cell lung cancer. J. Clin. Oncol. 24, 1428-1434 (2006). (Pubitemid 46622009)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.9
, pp. 1428-1434
-
-
Paz-Ares, L.1
Douillard, J.-Y.2
Koralewski, P.3
Manegold, C.4
Smit, E.F.5
Reyes, J.M.6
Chang, G.-C.7
John, W.J.8
Peterson, P.M.9
Obasaju, C.K.10
Lahn, M.11
Gandara, D.R.12
-
129
-
-
78049425319
-
Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer
-
Kwak, E. L. et al. Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer. N. Engl. J. Med. 363, 1693-1703 (2010).
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 1693-1703
-
-
Kwak, E.L.1
-
130
-
-
70449698237
-
Human epidermal growth factor receptor 2-positive breast cancer and central nervous system metastases
-
Leyland-Jones, B. Human epidermal growth factor receptor 2-positive breast cancer and central nervous system metastases. J. Clin. Oncol. 27, 5278-5286 (2009).
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 5278-5286
-
-
Leyland-Jones, B.1
-
131
-
-
34250174543
-
Brain metastases: The HER2 paradigm
-
DOI 10.1158/1078-0432.CCR-06-2478
-
Lin, N. U. & Winer, E. P. Brain metastases: the HER2 paradigm. Clin. Cancer Res. 13, 1648-1655 (2007). (Pubitemid 46952930)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.6
, pp. 1648-1655
-
-
Lin, N.U.1
Winer, E.P.2
-
132
-
-
79551514024
-
MicroRNA-1258 suppresses breast cancer brain metastasis by targeting heparanase
-
Zhang, L., Sullivan, P. S., Goodman, J. C., Gunaratne, P. H. & Marchetti, D. MicroRNA-1258 suppresses breast cancer brain metastasis by targeting heparanase. Cancer Res. 71, 645-654 (2011).
-
(2011)
Cancer Res.
, vol.71
, pp. 645-654
-
-
Zhang, L.1
Sullivan, P.S.2
Goodman, J.C.3
Gunaratne, P.H.4
Marchetti, D.5
-
133
-
-
42949112556
-
Phase II trial of lapatinib for brain metastases in patients with human epidermal growth factor receptor 2-positive breast cancer
-
Lin, N. U. et al. Phase II trial of lapatinib for brain metastases in patients with human epidermal growth factor receptor 2-positive breast cancer. J. Clin. Oncol. 26, 1993-1999 (2008).
-
(2008)
J. Clin. Oncol.
, vol.26
, pp. 1993-1999
-
-
Lin, N.U.1
-
134
-
-
63149110733
-
Multicenter phase II study of lapatinib in patients with brain metastases from HER2-positive breast cancer
-
Lin, N. U. et al. Multicenter phase II study of lapatinib in patients with brain metastases from HER2-positive breast cancer. Clin. Cancer Res. 15, 1452-1459 (2009).
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 1452-1459
-
-
Lin, N.U.1
-
135
-
-
56549113680
-
A phase III randomized comparison of lapatinib plus capecitabine versus capecitabine alone in women with advanced breast cancer that has progressed on trastuzumab: Updated efficacy and biomarker analyses
-
Cameron, D. et al. A phase III randomized comparison of lapatinib plus capecitabine versus capecitabine alone in women with advanced breast cancer that has progressed on trastuzumab: updated efficacy and biomarker analyses. Breast Cancer Res. Treat. 112, 533-543 (2008).
-
(2008)
Breast Cancer Res. Treat.
, vol.112
, pp. 533-543
-
-
Cameron, D.1
-
136
-
-
79958075844
-
-
US National Library of Medicine [online]
-
US National Library of Medicine. Clinicaltrials.gov [online], http://clinicaltrials.gov/ct2/show/NCT01004172 (2011).
-
(2011)
-
-
-
137
-
-
77956030786
-
Inhibition of mutated, activated BRAF in metastatic melanoma
-
Flaherty, K. T. et al. Inhibition of mutated, activated BRAF in metastatic melanoma. N. Engl. J. Med. 363, 809-819 (2010).
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 809-819
-
-
Flaherty, K.T.1
-
138
-
-
79953891558
-
Phase 1/2 study of GSK2118436, a selective inhibitor of V600 mutant (MUT) BRAF kinase; evidence of activity in melanoma brain metastases (METS) [abstract]
-
Long, G. V. et al. Phase 1/2 study of GSK2118436, a selective inhibitor of V600 mutant (MUT) BRAF kinase; evidence of activity in melanoma brain metastases (METS) [abstract]. Ann. Oncol. 21, viii12 (2010).
-
(2010)
Ann. Oncol.
, vol.21
-
-
Long, G.V.1
-
139
-
-
0035852648
-
Integrin activation controls metastasis in human breast cancer
-
DOI 10.1073/pnas.98.4.1853
-
Felding-Habermann, B. et al. Integrin activation controls metastasis in human breast cancer. Proc. Natl Acad. Sci. USA 98, 1853-1858 (2001). (Pubitemid 32165587)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.4
, pp. 1853-1858
-
-
Felding-Habermann, B.1
O'Toole, T.E.2
Smith, J.W.3
Fransvea, E.4
Ruggeri, Z.M.5
Ginsberg, M.H.6
Hughes, P.E.7
Pampori, N.8
Shattil, S.J.9
Saven, A.10
Mueller, B.M.11
-
140
-
-
70349484491
-
Analyses of resected human brain metastases of breast cancer reveal the association between up-regulation of hexokinase 2 and poor prognosis
-
Palmieri, D. et al. Analyses of resected human brain metastases of breast cancer reveal the association between up-regulation of hexokinase 2 and poor prognosis. Mol. Cancer Res. 7, 1438-1445 (2009).
-
(2009)
Mol. Cancer Res.
, vol.7
, pp. 1438-1445
-
-
Palmieri, D.1
-
141
-
-
77952821751
-
FOXC1 is a potential prognostic biomarker with functional significance in basal-like breast cancer
-
Ray, P. S. et al. FOXC1 is a potential prognostic biomarker with functional significance in basal-like breast cancer. Cancer Res. 70, 3870-3876 (2010).
-
(2010)
Cancer Res.
, vol.70
, pp. 3870-3876
-
-
Ray, P.S.1
-
142
-
-
67649662201
-
WNT/TCF signaling through LEF1 and HOXB9 mediates lung adenocarcinoma metastasis
-
Nguyen, D. X. et al. WNT/TCF signaling through LEF1 and HOXB9 mediates lung adenocarcinoma metastasis. Cell 138, 51-62 (2009).
-
(2009)
Cell
, vol.138
, pp. 51-62
-
-
Nguyen, D.X.1
-
143
-
-
63449101161
-
The expression of three genes in primary non-small cell lung cancer is associated with metastatic spread to the brain
-
Grinberg-Rashi, H. et al. The expression of three genes in primary non-small cell lung cancer is associated with metastatic spread to the brain. Clin. Cancer Res. 15, 1755-1761 (2009).
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 1755-1761
-
-
Grinberg-Rashi, H.1
-
144
-
-
33645532055
-
Activation of stat3 in human melanoma promotes brain metastasis
-
Xie, T. X. et al. Activation of Stat3 in human melanoma promotes brain metastasis. Cancer Res. 66, 3188-3196 (2006).
-
(2006)
Cancer Res.
, vol.66
, pp. 3188-3196
-
-
Xie, T.X.1
-
145
-
-
48249107113
-
Activation of notch signaling in a xenograft model of brain metastasis
-
Nam, D. H. et al. Activation of notch signaling in a xenograft model of brain metastasis. Clin. Cancer Res. 14, 4059-4066 (2008).
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 4059-4066
-
-
Nam, D.H.1
-
146
-
-
0023118457
-
Alteration of blood-brain-CSF barrier in experimental meningeal carcinomatosis: A morphologic and adriamycin-penetration study
-
DOI 10.1007/BF00150615
-
Siegal, T. et al. Alteration of blood-brain-CSF barrier in experimental meningeal carcinomatosis. A morphologic and adriamycin-penetration study. J. Neurooncol. 4, 233-242 (1987). (Pubitemid 17023824)
-
(1987)
Journal of Neuro-Oncology
, vol.4
, Issue.3
, pp. 233-242
-
-
Siegal, T.1
Sandbank, U.2
Gabizon, A.3
-
147
-
-
0031801174
-
Animal models of leptomeningeal metastasis
-
DOI 10.1023/A:1005936304256
-
Schabet, M. & Herrlinger, U. Animal models of leptomeningeal metastasis. J. Neurooncol. 38, 199-205 (1998). (Pubitemid 28306208)
-
(1998)
Journal of Neuro-Oncology
, vol.38
, Issue.2-3
, pp. 199-205
-
-
Schabet, M.1
Herrlinger, U.2
-
148
-
-
0024331909
-
Unique patterns of brain metastasis produced by different human carcinomas in athymic nude mice
-
DOI 10.1002/ijc.2910440524
-
Schackert, G., Price, J. E., Bucana, C. D. & Fidler, I. J. Unique patterns of brain metastasis produced by different human carcinomas in athymic nude mice. Int. J. Cancer 44, 892-897 (1989). (Pubitemid 20007989)
-
(1989)
International Journal of Cancer
, vol.44
, Issue.5
, pp. 892-897
-
-
Schackert, G.1
Price, J.E.2
Bucana, C.D.3
Fidler, I.J.4
-
149
-
-
0041562478
-
MART-1 adenovirus-transduced dendritic cell immunization in a murine model of metastatic central nervous system tumor
-
DOI 10.1023/A:1024921506081
-
Broder, H., Anderson, A., Kremen, T. J., Odesa, S. K. & Liau, L. M. MART-1 adenovirus-transduced dendritic cell immunization in a murine model of metastatic central nervous system tumor. J. Neurooncol. 64, 21-30 (2003). (Pubitemid 36992457)
-
(2003)
Journal of Neuro-Oncology
, vol.64
, Issue.1-2
, pp. 21-30
-
-
Broder, H.1
Anderson, A.2
Kremen, T.J.3
Odesa, S.K.4
Liau, L.M.5
-
150
-
-
0023893807
-
Development of in vivo models for studies of brain metastasis
-
Schackert, G. & Fidler, I. J. Development of in vivo models for studies of brain metastasis. Int. J. Cancer 41, 589-594 (1988).
-
(1988)
Int. J. Cancer
, vol.41
, pp. 589-594
-
-
Schackert, G.1
Fidler, I.J.2
-
151
-
-
0023942541
-
Site-specific metastasis of mouse melanomas and a fibrosarcoma in the brain or meninges of syngeneic animals
-
Schackert, G. & Fidler, I. J. Site-specific metastasis of mouse melanomas and a fibrosarcoma in the brain or meninges of syngeneic animals. Cancer Res. 48, 3478-3484 (1988).
-
(1988)
Cancer Res.
, vol.48
, pp. 3478-3484
-
-
Schackert, G.1
Fidler, I.J.2
-
152
-
-
0032733840
-
Genetically fluorescent melanoma bone and organ metastasis models
-
Yang, M. et al. Genetically fluorescent melanoma bone and organ metastasis models. Clin. Cancer Res. 5, 3549-3559 (1999).
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 3549-3559
-
-
Yang, M.1
-
153
-
-
34250182404
-
Chemotherapy delivery issues in central nervous system malignancy: A reality check
-
DOI 10.1200/JCO.2006.09.9861
-
Muldoon, L. L. et al. Chemotherapy delivery issues in central nervous system malignancy: a reality check. J. Clin. Oncol. 25, 2295-2305 (2007). (Pubitemid 46954658)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.16
, pp. 2295-2305
-
-
Muldoon, L.L.1
Soussain, C.2
Jahnke, K.3
Johanson, C.4
Siegal, T.5
Smith, Q.R.6
Hall, W.A.7
Hynynen, K.8
Senter, P.D.9
Peereboom, D.M.10
Neuwelt, E.A.11
-
154
-
-
51249091226
-
Recent advances in blood-brain barrier disruption as a CNS delivery strategy
-
Bellavance, M. A., Blanchette, M. & Fortin, D. Recent advances in blood-brain barrier disruption as a CNS delivery strategy. AAPS J. 10, 166-177 (2008).
-
(2008)
AAPS J.
, vol.10
, pp. 166-177
-
-
Bellavance, M.A.1
Blanchette, M.2
Fortin, D.3
-
155
-
-
0032776321
-
Phase II studies of RMP-7 and carboplatin in the treatment of recurrent high grade glioma. RMP-7 european study group
-
Gregor, A. et al. Phase II studies of RMP-7 and carboplatin in the treatment of recurrent high grade glioma. RMP-7 European Study Group. J. Neurooncol. 44, 137-145 (1999).
-
(1999)
J. Neurooncol.
, vol.44
, pp. 137-145
-
-
Gregor, A.1
-
156
-
-
0029900093
-
Enhanced tumor uptake of carboplatin and survival in glioma-bearing rats by intracarotid infusion of bradykinin analog, RMP-7
-
Matsukado, K. et al. Enhanced tumor uptake of carboplatin and survival in glioma-bearing rats by intracarotid infusion of bradykinin analog, RMP-7. Neurosurgery 39, 125-133 (1996).
-
(1996)
Neurosurgery
, vol.39
, pp. 125-133
-
-
Matsukado, K.1
-
157
-
-
0037388250
-
A randomized, double-blind, placebo-controlled, phase 2 study of RMP-7 in combination with carboplatin administered intravenously for the treatment of recurrent malignant glioma
-
DOI 10.1215/S1522851702000340
-
Prados, M. D. et al. A randomized, double-blind, placebo-controlled, phase 2 study of RMP-7 in combination with carboplatin administered intravenously for the treatment of recurrent malignant glioma. Neuro Oncol. 5, 96-103 (2003). (Pubitemid 36416838)
-
(2003)
Neuro-Oncology
, vol.5
, Issue.2
, pp. 96-103
-
-
Prados, M.D.1
Schold Jr., S.C.2
Fine, H.A.3
Jaeckle, K.4
Hochberg, F.5
Mechtler, L.6
Fetell, M.R.7
Phuphanich, S.8
Feun, L.9
Janus, T.J.10
Ford, K.11
Graney, W.12
-
158
-
-
34547642139
-
Blood-brain barrier transport of therapeutics via receptor-mediation
-
DOI 10.1007/s11095-007-9379-0
-
Jones, A. R. & Shusta, E. V. Blood-brain barrier transport of therapeutics via receptor-mediation. Pharm. Res. 24, 1759-1771 (2007). (Pubitemid 47206625)
-
(2007)
Pharmaceutical Research
, vol.24
, Issue.9
, pp. 1759-1771
-
-
Jones, A.R.1
Shusta, E.V.2
-
159
-
-
38749125060
-
Oral paclitaxel chemotherapy for brain tumors: Ideal combination treatment of paclitaxel and P-glycoprotein inhibitor
-
Joo, K. M. et al. Oral paclitaxel chemotherapy for brain tumors: ideal combination treatment of paclitaxel and p-glycoprotein inhibitor. Oncol. Rep. 19, 17-23 (2008). (Pubitemid 351176126)
-
(2008)
Oncology Reports
, vol.19
, Issue.1
, pp. 17-23
-
-
Joo, K.M.1
Park, K.2
Kong, D.-S.3
Song, S.Y.4
Kim, M.H.5
Lee, G.S.6
Kim, M.S.7
Nam, D.-H.8
-
160
-
-
54049101626
-
Response of brain specific microenvironment to p-glycoprotein inhibitor: An important factor determining therapeutic effect of p-glycoprotein inhibitor on brain metastatic tumors
-
Joo, K. M. et al. Response of brain specific microenvironment to p-glycoprotein inhibitor: an important factor determining therapeutic effect of p-glycoprotein inhibitor on brain metastatic tumors. Int. J. Oncol. 33, 705-712 (2008).
-
(2008)
Int. J. Oncol.
, vol.33
, pp. 705-712
-
-
Joo, K.M.1
-
161
-
-
12744253433
-
Modulation of p-glycoprotein transport function at the blood-brain barrier
-
Bauer, B., Hartz, A. M., Fricker, G. & Miller, D. S. Modulation of p-glycoprotein transport function at the blood-brain barrier. Exp. Biol. Med. 230, 118-127 (2005).
-
(2005)
Exp. Biol. Med.
, vol.230
, pp. 118-127
-
-
Bauer, B.1
Hartz, A.M.2
Fricker, G.3
Miller, D.S.4
|