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Volumn 16, Issue 7, 2014, Pages 685-694

Colon cancer cells colonize the lung from established liver metastases through p38 MAPK signalling and PTHLH

(18)  Urosevic, Jelena a   Garcia Albéniz, Xabier a,b   Planet, Evarist a   Real, Sebastián a   Céspedes, María Virtudes c,d   Guiu, Marc a   Fernandez, Esther a   Bellmunt, Anna a   Gawrzak, Sylwia a   Pavlovic, Milica a   Mangues, Ramon c,d   Dolado, Ignacio a,g   Barriga, Francisco M a   Nadal, Cristina b   Kemeny, Nancy e   Batlle, Eduard a,f   Nebreda, Angel R a,f   Gomis, Roger R a,f  


Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CYTOKINE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PARATHYROID HORMONE LIKE HORMONE; UNCLASSIFIED DRUG;

EID: 84903793785     PISSN: 14657392     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/ncb2977     Document Type: Article
Times cited : (127)

References (42)
  • 2
    • 77952994052 scopus 로고    scopus 로고
    • Metastatic colorectal cancer: From improved survival to potential cure
    • Gallagher, D. J. & Kemeny, N. Metastatic colorectal cancer: from improved survival to potential cure. Oncology 78, 237-248 (2010).
    • (2010) Oncology , vol.78 , pp. 237-248
    • Gallagher, D.J.1    Kemeny, N.2
  • 3
    • 84868198400 scopus 로고    scopus 로고
    • Meeting the biologic challenge of colorectal metastases
    • Wanebo, H. J. et al. Meeting the biologic challenge of colorectal metastases. Clin. Exp. Metastasis 29, 821-839 (2012).
    • (2012) Clin. Exp. Metastasis , vol.29 , pp. 821-839
    • Wanebo, H.J.1
  • 4
    • 10744232581 scopus 로고    scopus 로고
    • Recurrence patterns after curative resection of colorectal cancer in patients followed for a minimum of ten years
    • Sadahiro, S. et al. Recurrence patterns after curative resection of colorectal cancer in patients followed for a minimum of ten years. Hepatogastroenterology 50, 1362-1366 (2003).
    • (2003) Hepatogastroenterology , vol.50 , pp. 1362-1366
    • Sadahiro, S.1
  • 5
    • 0036224250 scopus 로고    scopus 로고
    • Follow-up of patients with colorectal cancer: Numbers needed to test and treat
    • Kievit, J. Follow-up of patients with colorectal cancer: numbers needed to test and treat. Eur. J. Cancer 38, 986-999 (2002).
    • (2002) Eur. J. Cancer , vol.38 , pp. 986-999
    • Kievit, J.1
  • 6
    • 63049090100 scopus 로고    scopus 로고
    • From dissemination to organspecific colonization
    • Nguyen, D. X., Bos, P. D. & Massagué, J. Metastasis: from dissemination to organspecific colonization. Nat. Rev. Cancer 9, 274-284 (2009).
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 274-284
    • Nguyen, D.X.1    Bos, P.D.2    Metastasis, M.J.3
  • 8
    • 33748774151 scopus 로고    scopus 로고
    • Organ-specific metastatic tumor cell adhesion and extravasation of colon carcinoma cells with different metastatic potential
    • Schlüter, K. et al. Organ-specific metastatic tumor cell adhesion and extravasation of colon carcinoma cells with different metastatic potential. Am. J. Pathol. 169, 1064-1073 (2006).
    • (2006) Am. J. Pathol. , vol.169 , pp. 1064-1073
    • Schlüter, K.1
  • 9
    • 77951139631 scopus 로고    scopus 로고
    • Genome remodelling in a basal-like breast cancer metastasis and xenograft
    • Ding, L. et al. Genome remodelling in a basal-like breast cancer metastasis and xenograft. Nature 464, 999-1005 (2010).
    • (2010) Nature , vol.464 , pp. 999-1005
    • Ding, L.1
  • 10
    • 0038481970 scopus 로고    scopus 로고
    • The Pathogenesis of Cancer Metastasis: The 'seed and soil' hypothesis revisited
    • Fidler, I. J. The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited. Nat. Rev. Cancer 3, 453-458 (2003).
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 453-458
    • Fidler, I.J.1
  • 11
    • 39749137048 scopus 로고    scopus 로고
    • Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer
    • Kaiser, S. et al. Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer. Genome Biol. 8, R131 (2007).
    • (2007) Genome Biol. , vol.8
    • Kaiser, S.1
  • 12
    • 77249143960 scopus 로고    scopus 로고
    • Experimentally derived metastasis gene expression profile predicts recurrence and death in patients with colon cancer
    • Smith, J. J. et al. Experimentally derived metastasis gene expression profile predicts recurrence and death in patients with colon cancer. Gastroenterology 138, 958-968 (2010).
    • (2010) Gastroenterology , vol.138 , pp. 958-968
    • Smith, J.J.1
  • 13
    • 79955681163 scopus 로고    scopus 로고
    • The intestinal stem cell signature identifies colorectal cancer stem cells and predicts disease relapse
    • Merlos-Suárez, A. et al. The intestinal stem cell signature identifies colorectal cancer stem cells and predicts disease relapse. Cell Stem Cell 8, 511-524 (2011).
    • (2011) Cell Stem Cell , vol.8 , pp. 511-524
    • Merlos-Suárez, A.1
  • 14
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
    • Subramanian, A. et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc. Natl Acad. Sci. USA 102, 15545-15550 (2005).
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 15545-15550
    • Subramanian, A.1
  • 15
    • 67749117934 scopus 로고    scopus 로고
    • Signal integration by JNK and p38 MAPK pathways in cancer development
    • Wagner, E. F. & Nebreda, A. R. Signal integration by JNK and p38 MAPK pathways in cancer development. Nat. Rev. Cancer 9, 537-549 (2009).
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 537-549
    • Wagner, E.F.1    Nebreda, A.R.2
  • 16
    • 77955059513 scopus 로고    scopus 로고
    • Mechanisms and functions of p38 mapk signaling
    • Cuadrado, A. & Nebreda, A. R. Mechanisms and functions of p38 MAPK signalling. Biochem. J. 429, 403-417 (2010).
    • (2010) Biochem. J. , vol.429 , pp. 403-417
    • Cuadrado, A.1    Nebreda, A.R.2
  • 17
    • 77950353276 scopus 로고    scopus 로고
    • ERK2 but not ERK1 induces epithelial-to-mesenchymal transformation via DEF motif-dependent signaling events
    • Shin, S., Dimitri, C. A., Yoon, S-O., Dowdle, W. & Blenis, J. ERK2 but not ERK1 induces epithelial-to-mesenchymal transformation via DEF motif-dependent signaling events. Mol. Cell 38, 114-127 (2010).
    • (2010) Mol. Cell , vol.38 , pp. 114-127
    • Shin, S.1    Dimitri, C.A.2    Yoon, S.-O.3    Dowdle, W.4    Blenis, J.5
  • 18
    • 84863040887 scopus 로고    scopus 로고
    • Discovery and characterization of atropisomer PH-797804, a p38 MAP kinase inhibitor, as a clinical drug candidate
    • Xing, L. et al. Discovery and characterization of atropisomer PH-797804, a p38 MAP kinase inhibitor, as a clinical drug candidate. Chem. Med. Chem. 7, 273-280 (2012).
    • (2012) Chem. Med. Chem. , vol.7 , pp. 273-280
    • Xing, L.1
  • 19
    • 34247876271 scopus 로고    scopus 로고
    • Orthotopic microinjection of human colon cancer cells in nude mice induces tumor foci in all clinically relevant metastatic sites
    • Céspedes, M. V. et al. Orthotopic microinjection of human colon cancer cells in nude mice induces tumor foci in all clinically relevant metastatic sites. Am. J. Pathol. 170, 1077-1085 (2007).
    • (2007) Am. J. Pathol. , vol.170 , pp. 1077-1085
    • Céspedes, M.V.1
  • 20
    • 35848958601 scopus 로고    scopus 로고
    • Integration of signaling pathways regulating chondrocyte differentiation during endochondral bone formation
    • Adams, S. L., Cohen, A. J. & Lassová, L. Integration of signaling pathways regulating chondrocyte differentiation during endochondral bone formation. J. Cell. Physiol. 213, 635-641 (2007).
    • (2007) J. Cell. Physiol. , vol.213 , pp. 635-641
    • Adams, S.L.1    Cohen, A.J.2    Lassová, L.3
  • 21
    • 34247381705 scopus 로고    scopus 로고
    • BMP4 and PTHrP interact to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction
    • Hens, J. R. et al. BMP4 and PTHrP interact to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction. Development 134, 1221-1230 (2007).
    • (2007) Development , vol.134 , pp. 1221-1230
    • Hens, J.R.1
  • 22
    • 56349169766 scopus 로고    scopus 로고
    • An increase in intracellular Ca2C is required for the activation of mitochondrial calpain to release AIF during cell death
    • Norberg, E. et al. An increase in intracellular Ca2C is required for the activation of mitochondrial calpain to release AIF during cell death. Cell Death Differ. 15, 1857-1864 (2008).
    • (2008) Cell Death Differ. , vol.15 , pp. 1857-1864
    • Norberg, E.1
  • 23
    • 33751239138 scopus 로고    scopus 로고
    • Apoptosis in retinal degeneration involves cross-talk between apoptosis-inducing factor (AIF) and caspase-12 and is blocked by calpain inhibitors
    • Sanges, D., Comitato, A., Tammaro, R. & Marigo, V. Apoptosis in retinal degeneration involves cross-talk between apoptosis-inducing factor (AIF) and caspase-12 and is blocked by calpain inhibitors. Proc. Natl Acad. Sci. USA 103, 17366-17371 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 17366-17371
    • Sanges, D.1    Comitato, A.2    Tammaro, R.3    Marigo, V.4
  • 24
    • 78650968168 scopus 로고    scopus 로고
    • Molecular basis of parathyroid hormone receptor signaling and trafficking: A family B GPCR paradigm
    • Vilardaga, J-P., Romero, G., Friedman, P. A. & Gardella, T. J. Molecular basis of parathyroid hormone receptor signaling and trafficking: a family B GPCR paradigm. Cell. Mol. Life Sci. 68, 1-13 (2011).
    • (2011) Cell. Mol. Life Sci. , vol.68 , pp. 1-13
    • Vilardaga, J.-P.1    Romero, G.2    Friedman, P.A.3    Gardella, T.J.4
  • 25
    • 0034698733 scopus 로고    scopus 로고
    • Two distinct pathways leading to nuclear apoptosis
    • Susin, S. A. et al. Two distinct pathways leading to nuclear apoptosis. J. Exp. Med. 192, 571-580 (2000).
    • (2000) J. Exp. Med. , vol.192 , pp. 571-580
    • Susin, S.A.1
  • 26
    • 0035967169 scopus 로고    scopus 로고
    • Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death
    • Joza, N. et al. Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death. Nature 410, 549-554 (2001).
    • (2001) Nature , vol.410 , pp. 549-554
    • Joza, N.1
  • 27
    • 0036853893 scopus 로고    scopus 로고
    • Guanosine nucleotides inhibit different syndromes of PTHrP excess caused by human cancers in vivo
    • Gallwitz, W. E., Guise, T. A. & Mundy, G. R. Guanosine nucleotides inhibit different syndromes of PTHrP excess caused by human cancers in vivo. J. Clin. Invest. 110, 1559-1572 (2002).
    • (2002) J. Clin. Invest. , vol.110 , pp. 1559-1572
    • Gallwitz, W.E.1    Guise, T.A.2    Mundy, G.R.3
  • 28
    • 77951553897 scopus 로고    scopus 로고
    • Parathyroid-related protein plays a critical role in bone invasion by oral squamous cell carcinoma
    • Takayama, Y., Mori, T., Nomura, T., Shibahara, T. & Sakamoto, M. Parathyroid-related protein plays a critical role in bone invasion by oral squamous cell carcinoma. Int. J. Oncol. 36, 1387-1394 (2010).
    • (2010) Int. J. Oncol. , vol.36 , pp. 1387-1394
    • Takayama, Y.1    Mori, T.2    Nomura, T.3    Shibahara, T.4    Sakamoto, M.5
  • 29
    • 0034658725 scopus 로고    scopus 로고
    • Molecular mechanisms of osteolytic bone metastases
    • Guise, T. A. Molecular mechanisms of osteolytic bone metastases. Cancer 88, 2892-2898 (2000).
    • (2000) Cancer , vol.88 , pp. 2892-2898
    • Guise, T.A.1
  • 30
    • 0029887030 scopus 로고    scopus 로고
    • Parathyroid hormone-related protein expression in the human colon: Immunohistochemical evaluation
    • Malakouti, S., Asadi, F. K., Kukreja, S. C., Abcarian, H. A. & Cintron, J. R. Parathyroid hormone-related protein expression in the human colon: immunohistochemical evaluation. Am. Surg. 62, 540-544 (1996).
    • (1996) Am. Surg. , vol.62 , pp. 540-544
    • Malakouti, S.1    Asadi, F.K.2    Kukreja, S.C.3    Abcarian, H.A.4    Cintron, J.R.5
  • 31
    • 2442562277 scopus 로고    scopus 로고
    • A novel triple-modality reporter gene for whole-body fluorescent, bioluminescent, and nuclear noninvasive imaging
    • Ponomarev, V. et al. A novel triple-modality reporter gene for whole-body fluorescent, bioluminescent, and nuclear noninvasive imaging. Eur. J. Nucl. Med. Mol. Imaging 31, 740-751 (2004).
    • (2004) Eur. J. Nucl. Med. Mol. Imaging , vol.31 , pp. 740-751
    • Ponomarev, V.1
  • 32
    • 0022625913 scopus 로고
    • Metastatic behavior of tumor cells isolated from primary and metastatic human colorectal carcinomas implanted into different sites in nude mice
    • Giavazzi, R., Campbell, D. E., Jessup, J. M., Cleary, K. & Fidler, I. J. Metastatic behavior of tumor cells isolated from primary and metastatic human colorectal carcinomas implanted into different sites in nude mice. Cancer Res. 46, 1928-1933 (1986).
    • (1986) Cancer Res. , vol.46 , pp. 1928-1933
    • Giavazzi, R.1    Campbell, D.E.2    Jessup, J.M.3    Cleary, K.4    Fidler, I.J.5
  • 33
    • 34247876271 scopus 로고    scopus 로고
    • Orthotopic microinjection of human colon cancer cells in nude mice induces tumor foci in all clinically relevant metastatic sites
    • Céspedes, M. V. et al. Orthotopic microinjection of human colon cancer cells in nude mice induces tumor foci in all clinically relevant metastatic sites. Am. J. Pathol. 170, 1077-1085 (2007).
    • (2007) Am. J. Pathol. , vol.170 , pp. 1077-1085
    • Céspedes, M.V.1
  • 34
    • 28744458859 scopus 로고    scopus 로고
    • Bioconductor: Open software development for computational biology and bioinformatics
    • Gentleman, R. C. et al. Bioconductor: open software development for computational biology and bioinformatics. Genome Biol. 5, R80 (2004).
    • (2004) Genome Biol. , vol.5
    • Gentleman, R.C.1
  • 35
    • 43149118132 scopus 로고    scopus 로고
    • Semi-parametric differential, expression analysis via partial mixture estimation
    • Rossell, D., Guerra, R. & Scott, C. Semi-parametric differential, expression analysis via partial mixture estimation. Stat. Appl. Genet. Mol. Biol. 7, Article15 (2008).
    • (2008) Stat. Appl. Genet. Mol. Biol. , vol.7 , pp. 15
    • Rossell, D.1    Guerra, R.2    Scott, C.3
  • 37
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: A practical and powerful approach to multiple testing
    • Benjamini, Y. & Hochberg, Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J. Roy. Stat. Soc. Ser. B 57, 289-300 (1995).
    • (1995) J. Roy. Stat. Soc. Ser. , vol.B57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 38
    • 0034704178 scopus 로고    scopus 로고
    • Differential activation of p38 mitogen-activated protein kinase isoforms depending on signal strength
    • Alonso, G., Ambrosino, C., Jones, M. & Nebreda, A. R. Differential activation of p38 mitogen-activated protein kinase isoforms depending on signal strength. J. Biol. Chem. 275, 40641-40648 (2000).
    • (2000) J. Biol. Chem. , vol.275 , pp. 40641-40648
    • Alonso, G.1    Ambrosino, C.2    Jones, M.3    Nebreda, A.R.4
  • 39
    • 79953832950 scopus 로고    scopus 로고
    • Serum matrilysin correlates with poor survival independently of KRAS and BRAF status in refractory advanced colorectal cancer patients treated with irinotecan plus cetuximab
    • Garcia-Albeniz, X. et al. Serum matrilysin correlates with poor survival independently of KRAS and BRAF status in refractory advanced colorectal cancer patients treated with irinotecan plus cetuximab. Tumour Biol. 32, 417-424 (2011).
    • (2011) Tumour Biol. , vol.32 , pp. 417-424
    • Garcia-Albeniz, X.1
  • 40
    • 64249148344 scopus 로고    scopus 로고
    • Serum matrilysin levels predict outcome in curatively resected colorectal cancer patients
    • Martínez-Fernandez, A. et al. Serum matrilysin levels predict outcome in curatively resected colorectal cancer patients. Ann. Surg. Oncol. 16, 1412-1420 (2009).
    • (2009) Ann. Surg. Oncol. , vol.16 , pp. 1412-1420
    • Martínez-Fernandez, A.1
  • 41
    • 77249143960 scopus 로고    scopus 로고
    • Experimentally derived metastasis gene expression profile predicts recurrence and death in patients with colon cancer
    • Smith, J. J. et al. Experimentally derived metastasis gene expression profile predicts recurrence and death in patients with colon cancer. Gastroenterology 138, 958-968 (2010).
    • (2010) Gastroenterology , vol.138 , pp. 958-968
    • Smith, J.J.1
  • 42
    • 73349088103 scopus 로고    scopus 로고
    • Metastasis-associated gene expression changes predict poor outcomes in patients with dukes stage B and C colorectal cancer
    • Jorissen, R. N. et al. Metastasis-associated gene expression changes predict poor outcomes in patients with dukes stage B and C colorectal cancer. Clin. Cancer Res. 15, 7642-7651 (2009).
    • (2009) Clin. Cancer Res. , vol.15 , pp. 7642-7651
    • Jorissen, R.N.1


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