Mechanism of Suppression of Chromosomal Instability by DNA Polymerase POLQ

PLoS Genetics

Volumn 10, Issue 10, 2014, Pages

  Yousefzadeh, Matthew J ^a,b   Wyatt, David W ^c   Takata, Kei ichi ^a,b   Mu, Yunxiang ^a   Hensley, Sean C ^a   Tomida, Junya ^a,b   Bylund, Göran O ^d   Doublié, Sylvie ^e   Johansson, Erik ^d   Ramsden, Dale A ^c   McBride, Kevin M ^a,b   Wood, Richard D ^a,b  

^a UNIVERSITY OF TEXAS   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d UMEÅ UNIVERSITY   (Sweden)

^e UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA POLYMERASE; DNA POLYMERASE THETA; UNCLASSIFIED DRUG; BLEOMYCIN; DNA DIRECTED DNA POLYMERASE;

ANIMAL CELL; ARTICLE; BASE PAIRING; BONE MARROW STROMA CELL; CHROMOSOMAL INSTABILITY; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; DNA END JOINING REPAIR; DOUBLE STRANDED DNA BREAK; EMBRYO; ENZYME ACTIVITY; FIBROBLAST; GENE LOCUS; GENE REARRANGEMENT; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; IMMUNOGLOBULIN GENE; IMMUNOGLOBULIN HEAVY CHAIN GENE; MOUSE; NONHUMAN; ONCOGENE MYC; POLQ GENE; ANIMAL; B LYMPHOCYTE; BONE MARROW CELL; C57BL MOUSE; CELL CULTURE; DRUG EFFECTS; FEMALE; GENETICS; HEK293 CELL LINE; METABOLISM; MUTANT MOUSE STRAIN; PHYSIOLOGY; RADIATION RESPONSE;

ANIMALS; B-LYMPHOCYTES; BLEOMYCIN; BONE MARROW CELLS; CELLS, CULTURED; CHROMOSOMAL INSTABILITY; DNA BREAKS, DOUBLE-STRANDED; DNA END-JOINING REPAIR; DNA-DIRECTED DNA POLYMERASE; FEMALE; HEK293 CELLS; HUMANS; IMMUNOGLOBULIN CLASS SWITCHING; METABOLIC NETWORKS AND PATHWAYS; MICE, INBRED C57BL; MICE, MUTANT STRAINS;

EID: 84908326310     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004654     Document Type: Article

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