Polymerase θ is a key driver of genome evolution and of CRISPR/Cas9-mediated mutagenesis

Nature Communications

Volumn 6, Issue , 2015, Pages

  Van Schendel, Robin ^a   Roerink, Sophie F ^a   Portegijs, Vincent ^b   Van Den Heuvel, Sander ^b   Tijsterman, Marcel ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CAS9 NUCLEASE; DNA POLYMERASE; DNA POLYMERASE THETA; ENDONUCLEASE; UNCLASSIFIED DRUG; CAENORHABDITIS ELEGANS PROTEIN; DNA DIRECTED DNA POLYMERASE;

CYTOLOGY; DNA; ENZYME ACTIVITY; EVOLUTIONARY BIOLOGY; GENOME; MUTATION;

ARTICLE; CAENORHABDITIS ELEGANS; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; DNA END JOINING REPAIR; DNA REPAIR; DOUBLE STRANDED DNA BREAK; GENE SEQUENCE; GENOME; GERM CELL; INDEL MUTATION; MUTAGENESIS; NONHUMAN; TRANSPOSON; ANIMAL; CRISPR CAS SYSTEM; GENETICS; GERMLINE MUTATION; METABOLISM; MOLECULAR EVOLUTION; MUTATION;

ANIMALIA; CAENORHABDITIS ELEGANS;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CRISPR-CAS SYSTEMS; DNA BREAKS, DOUBLE-STRANDED; DNA END-JOINING REPAIR; DNA REPAIR; DNA-DIRECTED DNA POLYMERASE; EVOLUTION, MOLECULAR; GENOME, HELMINTH; GERM CELLS; GERM-LINE MUTATION; MUTAGENESIS; MUTATION;

EID: 84935856905     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms8394     Document Type: Article

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