-
1
-
-
84948736158
-
The year in new drugs
-
Jarvis LM. 2015. The year in new drugs. Chem. Eng. News 93:11-16
-
(2015)
Chem. Eng. News
, vol.93
, pp. 11-16
-
-
Jarvis, L.M.1
-
2
-
-
29144531173
-
The druggable genome: An update
-
Russ AP, Lampel S. 2005. The druggable genome: An update. Drug Discov. Today 10:1607-10
-
(2005)
Drug Discov. Today
, vol.10
, pp. 1607-1610
-
-
Russ, A.P.1
Lampel, S.2
-
4
-
-
0015918260
-
Opiate receptor: Demonstration in nervous tissue
-
Pert CB, Snyder SH. 1973. Opiate receptor: demonstration in nervous tissue. Science 179:1011-14
-
(1973)
Science
, vol.179
, pp. 1011-1014
-
-
Pert, C.B.1
Snyder, S.H.2
-
5
-
-
0024614117
-
Selective and enantiospecific acylation ofopioid receptors by (1S,2S)-trans-2-isothiocyanato-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl] benzeneacetamide. Demonstration ofreceptor heterogeneity
-
DeCosta BR, Rothman RB, Bykov V, Jacobson AE, Rice KC. 1989. Selective and enantiospecific acylation ofopioid receptors by (1S,2S)-trans-2-isothiocyanato-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl] benzeneacetamide. Demonstration ofreceptor heterogeneity. J. Med. Chem. 32:281-83
-
(1989)
J. Med. Chem.
, vol.32
, pp. 281-283
-
-
DeCosta, B.R.1
Rothman, R.B.2
Bykov, V.3
Jacobson, A.E.4
Rice, K.C.5
-
6
-
-
0025719395
-
Dihydropyridine receptor of L-type Ca2+ channels: Identification of binding domains for [3H](+)-PN200-110 and [3H]azidopine within the1 subunit
-
Striessnig J, Murphy BJ, Catterall WA. 1991. Dihydropyridine receptor of L-type Ca2+ channels: identification of binding domains for [3H](+)-PN200-110 and [3H]azidopine within the1 subunit. PNAS 88:10769-73
-
(1991)
PNAS
, vol.88
, pp. 10769-10773
-
-
Striessnig, J.1
Murphy, B.J.2
Catterall, W.A.3
-
7
-
-
33846569938
-
Targeting mammalian target of rapamycin (mTOR) for health and diseases
-
Tsang CK, Qi H, Liu LF, Zheng XFS. 2007. Targeting mammalian target of rapamycin (mTOR) for health and diseases. Drug Discov. Today 12:112-14
-
(2007)
Drug Discov. Today
, vol.12
, pp. 112-114
-
-
Tsang, C.K.1
Qi, H.2
Liu, L.F.3
Zheng, X.F.S.4
-
8
-
-
0025647885
-
Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin
-
Bierer BE, Mattila PS, Standaert RF, Herzenberg LA, Burakoff SJ, et al. 1990. Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin. PNAS 87:9231-35
-
(1990)
PNAS
, vol.87
, pp. 9231-9235
-
-
Bierer, B.E.1
Mattila, P.S.2
Standaert, R.F.3
Herzenberg, L.A.4
Burakoff, S.J.5
-
9
-
-
84891751622
-
The druggable genome: Evaluation of drug targets in clinical trials suggests major shifts in molecular class and indication
-
Rask-Andersen M, Masuram S, Schiöth HB. 2014. The druggable genome: Evaluation of drug targets in clinical trials suggests major shifts in molecular class and indication. Annu. Rev. Pharmacol. Toxicol. 54:9-26
-
(2014)
Annu. Rev. Pharmacol. Toxicol.
, vol.54
, pp. 9-26
-
-
Rask-Andersen, M.1
Masuram, S.2
Schiöth, H.B.3
-
10
-
-
84920363474
-
Only three driver gene mutations are required for the development of lung and colorectal cancers
-
Tomasetti C, Marchionni L, Nowak MA, Parmigiani G, Vogelstein B. 2014. Only three driver gene mutations are required for the development of lung and colorectal cancers. PNAS 112:118-23
-
(2014)
PNAS
, vol.112
, pp. 118-123
-
-
Tomasetti, C.1
Marchionni, L.2
Nowak, M.A.3
Parmigiani, G.4
Vogelstein, B.5
-
11
-
-
84875490185
-
Cancer genome landscapes
-
Vogelstein B, Papadopoulos N, Velculescu VE, Zhou S, Diaz LAJ, Kinzler KW. 2013. Cancer genome landscapes. Science 339:1546-58
-
(2013)
Science
, vol.339
, pp. 1546-1558
-
-
Vogelstein, B.1
Papadopoulos, N.2
Velculescu, V.E.3
Zhou, S.4
Diaz, L.A.J.5
Kinzler, K.W.6
-
12
-
-
84880321156
-
Heterogeneity of tumor-induced gene expression changes in the human metabolic network
-
Hu J, Locasale JW, Bielas JH, O'Sullivan J, Sheahan K, et al. 2013. Heterogeneity of tumor-induced gene expression changes in the human metabolic network. Nat. Biotechnol. 31:522-29
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 522-529
-
-
Hu, J.1
Locasale, J.W.2
Bielas, J.H.3
O'Sullivan, J.4
Sheahan, K.5
-
13
-
-
84954137639
-
Approaches to validate and manipulate RNA targets with small molecules in cells
-
Childs-Disney JL, Disney MD. 2016. Approaches to validate and manipulate RNA targets with small molecules in cells. Annu. Rev. Pharmacol. Toxicol. 56:123-40
-
(2016)
Annu. Rev. Pharmacol. Toxicol.
, vol.56
, pp. 123-140
-
-
Childs-Disney, J.L.1
Disney, M.D.2
-
14
-
-
84954099191
-
RNA interference (RNAi)-based therapeutics: Delivering on the promise
-
Bobbin ML, Rossi JJ. 2016. RNA interference (RNAi)-based therapeutics: delivering on the promise? Annu. Rev. Pharmacol. Toxicol. 56:103-22
-
(2016)
Annu. Rev. Pharmacol. Toxicol.
, vol.56
, pp. 103-122
-
-
Bobbin, M.L.1
Rossi, J.J.2
-
15
-
-
84939794726
-
HaloPROTACS: Use of small molecule PROTACs to induce degradation of HaloTag fusion proteins
-
Buckley DL, Raina K, Darricarrere N, Hines J, Gustafson JL, et al. 2015. HaloPROTACS: use of small molecule PROTACs to induce degradation of HaloTag fusion proteins. ACS Chem. Biol. 10:1831-37
-
(2015)
ACS Chem. Biol.
, vol.10
, pp. 1831-1837
-
-
Buckley, D.L.1
Raina, K.2
Darricarrere, N.3
Hines, J.4
Gustafson, J.L.5
-
17
-
-
84895072822
-
Drugging unconventional targets: Insights from Huntington's disease
-
Yu S, Liang Y, Palacino J, Difiglia M, Lu B. 2014. Drugging unconventional targets: insights from Huntington's disease. Trends Pharmacol. Sci. 35:53-62
-
(2014)
Trends Pharmacol. Sci.
, vol.35
, pp. 53-62
-
-
Yu, S.1
Liang, Y.2
Palacino, J.3
Difiglia, M.4
Lu, B.5
-
18
-
-
0036285634
-
Mathematical models of protein kinase signal transduction
-
Heinrich R, Neel BG, Rapoport TA. 2002. Mathematical models of protein kinase signal transduction. Mol. Cell 9:957-70
-
(2002)
Mol. Cell
, vol.9
, pp. 957-970
-
-
Heinrich, R.1
Neel, B.G.2
Rapoport, T.A.3
-
19
-
-
20444419344
-
Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance
-
MacKeigan JP,Murphy LO, Blenis J. 2005. Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance. Nat. Cell Biol. 7:591-600
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 591-600
-
-
MacKeigan, J.P.1
Murphy, L.O.2
Blenis, J.3
-
21
-
-
84872779494
-
Protein Ser/Thr phosphatases - The ugly ducklings of cell signalling
-
Brautigan DL. 2013. Protein Ser/Thr phosphatases-the ugly ducklings of cell signalling. FEBS J. 280:324-45
-
(2013)
FEBS J.
, vol.280
, pp. 324-345
-
-
Brautigan, D.L.1
-
22
-
-
84872502581
-
Challenges and opportunities in the development of protein phosphatase-directed therapeutics
-
De Munter S, Köhn M, Bollen M. 2013. Challenges and opportunities in the development of protein phosphatase-directed therapeutics. ACS Chem. Biol. 18:36-45
-
(2013)
ACS Chem. Biol.
, vol.18
, pp. 36-45
-
-
De Munter, S.1
Köhn, M.2
Bollen, M.3
-
23
-
-
84872759784
-
Protein tyrosine phosphatases-from housekeeping enzymes to master regulators of signal transduction
-
Tonks NK. 2013. Protein tyrosine phosphatases-from housekeeping enzymes to master regulators of signal transduction. FEBS J. 280(2):346-78
-
(2013)
FEBS J.
, vol.280
, Issue.2
, pp. 346-378
-
-
Tonks, N.K.1
-
24
-
-
67949124765
-
Drug discovery and protein tyrosine phosphatases
-
Blaskovich MAT. 2009. Drug discovery and protein tyrosine phosphatases. Curr. Med. Chem. 16:2095-176
-
(2009)
Curr. Med. Chem.
, vol.16
, pp. 2095-2176
-
-
Blaskovich, M.A.T.1
-
25
-
-
71249131319
-
Phosphatases as targets for cancer treatment
-
Lazo JS,Wipf P. 2009. Phosphatases as targets for cancer treatment. Curr. Opin. Investig. Drugs 10:1297-304
-
(2009)
Curr. Opin. Investig. Drugs
, vol.10
, pp. 1297-1304
-
-
Lazo, J.S.1
Wipf, P.2
-
26
-
-
84939777334
-
Wip1 phosphatase in breast cancer
-
Emelyanov A, Bulavin DV. 2015. Wip1 phosphatase in breast cancer. Oncogene 34:4429-38
-
(2015)
Oncogene
, vol.34
, pp. 4429-4438
-
-
Emelyanov, A.1
Bulavin, D.V.2
-
27
-
-
79958082113
-
Optimization of a cyclic peptide inhibitor of Ser/Thr phosphatase PPM1D (Wip1)
-
Hayashi R, Tanoue K, Durell SR, Chatterjee DK, Jenkins LM, et al. 2011. Optimization of a cyclic peptide inhibitor of Ser/Thr phosphatase PPM1D (Wip1). Biochemistry 50:4537-49
-
(2011)
Biochemistry
, vol.50
, pp. 4537-4549
-
-
Hayashi, R.1
Tanoue, K.2
Durell, S.R.3
Chatterjee, D.K.4
Jenkins, L.M.5
-
28
-
-
84894080663
-
Allosteric Wip1 phosphatase inhibition through flap-subdomain interaction
-
Gilmartin AG, Faitg TH, Richter M, Groy A, Seefeld MA, et al. 2014. Allosteric Wip1 phosphatase inhibition through flap-subdomain interaction. Nat. Chem. Biol. 10:181-87
-
(2014)
Nat. Chem. Biol.
, vol.10
, pp. 181-187
-
-
Gilmartin, A.G.1
Faitg, T.H.2
Richter, M.3
Groy, A.4
Seefeld, M.A.5
-
29
-
-
84655169159
-
A small molecule inhibitor of p53-inducible protein phosphatase PPM1D
-
Yagi H, Chuman Y, Kozakai Y, Imagawa T, Takahashi Y, et al. 2012. A small molecule inhibitor of p53-inducible protein phosphatase PPM1D. Bioorg. Med. Chem. Lett. 22:729-32
-
(2012)
Bioorg. Med. Chem. Lett.
, vol.22
, pp. 729-732
-
-
Yagi, H.1
Chuman, Y.2
Kozakai, Y.3
Imagawa, T.4
Takahashi, Y.5
-
30
-
-
39149136831
-
Achemical inhibitor ofPPM1D that selectively kills cells overexpressing PPM1D
-
Rayter S, Elliott R, Travers J,RowlandsMG,Richardson TB, et al. 2007. Achemical inhibitor ofPPM1D that selectively kills cells overexpressing PPM1D. Oncogene 27:1036-44
-
(2007)
Oncogene
, vol.27
, pp. 1036-1044
-
-
Rayter, S.1
Elliott, R.2
Travers, J.3
Rowlands, M.G.4
Richardson, T.B.5
-
31
-
-
84882759003
-
Suppression of Ser/Thr phosphatase 4 (PP4C/PPP4C) mimics a novel post-mitotic action of fostriecin, producing mitotic slippage followed by tetraploid cell death
-
Theobald B, Bonness K, Musiyenko A, Andrews JF, Urban G, et al. 2013. Suppression of Ser/Thr phosphatase 4 (PP4C/PPP4C) mimics a novel post-mitotic action of fostriecin, producing mitotic slippage followed by tetraploid cell death. Mol. Cancer Res. 11:845-55
-
(2013)
Mol. Cancer Res.
, vol.11
, pp. 845-855
-
-
Theobald, B.1
Bonness, K.2
Musiyenko, A.3
Andrews, J.F.4
Urban, G.5
-
32
-
-
0028063201
-
Antitumor drug fostriecin inhibits the mitotic entry checkpoint and protein phosphatases 1 and 2A
-
Roberge M, Tudan C, Hung SM, Harder KW, Jirik FR, Anderson H. 1994. Antitumor drug fostriecin inhibits the mitotic entry checkpoint and protein phosphatases 1 and 2A. Cancer Res. 54:6115-21
-
(1994)
Cancer Res.
, vol.54
, pp. 6115-6121
-
-
Roberge, M.1
Tudan, C.2
Hung, S.M.3
Harder, K.W.4
Jirik, F.R.5
Anderson, H.6
-
33
-
-
84882965687
-
Inhibition of protein phosphatase 2A radiosensitizes pancreatic cancers by modulating CDC25C/CDK1 and homologous recombination repair
-
Wei D, Parsels LA, Karnak D, Davis MA, Parsels JD, et al. 2013. Inhibition of protein phosphatase 2A radiosensitizes pancreatic cancers by modulating CDC25C/CDK1 and homologous recombination repair. Clin. Cancer Res. 19:4422-32
-
(2013)
Clin. Cancer Res.
, vol.19
, pp. 4422-4432
-
-
Wei, D.1
Parsels, L.A.2
Karnak, D.3
Davis, M.A.4
Parsels, J.D.5
-
34
-
-
77954376747
-
Essential requirement for PP2A inhibition by the oncogenic receptor c-KIT suggests PP2A reactivation as a strategy to treat c-KIT+ cancers
-
Roberts KG, Smith AM, McDougall F, Carpenter H, Horan M, et al. 2010. Essential requirement for PP2A inhibition by the oncogenic receptor c-KIT suggests PP2A reactivation as a strategy to treat c-KIT+ cancers. Cancer Res. 70:5438-47
-
(2010)
Cancer Res.
, vol.70
, pp. 5438-5447
-
-
Roberts, K.G.1
Smith, A.M.2
McDougall, F.3
Carpenter, H.4
Horan, M.5
-
35
-
-
84904695005
-
FTY720 induces apoptosis of M2 subtype acute myeloid leukemia cells by targeting sphingolipid metabolism and increasing endogenous ceramide levels
-
Chen L, Luo LF, Lu J, Li L, Liu YF, et al. 2014. FTY720 induces apoptosis of M2 subtype acute myeloid leukemia cells by targeting sphingolipid metabolism and increasing endogenous ceramide levels. PLOS ONE 9:e103033
-
(2014)
PLOS ONE
, vol.9
, pp. e103033
-
-
Chen, L.1
Luo, L.F.2
Lu, J.3
Li, L.4
Liu, Y.F.5
-
36
-
-
84903449080
-
Targeting c-MYC by antagonizing PP2A inhibitors in breast cancer
-
Janghorban M, Farrell AS, Allen-Petersen BL, Pelz C, Daniel CJ, et al. 2014. Targeting c-MYC by antagonizing PP2A inhibitors in breast cancer. PNAS 111:9157-62
-
(2014)
PNAS
, vol.111
, pp. 9157-9162
-
-
Janghorban, M.1
Farrell, A.S.2
Allen-Petersen, B.L.3
Pelz, C.4
Daniel, C.J.5
-
37
-
-
84908300167
-
Effect of FTY720 on the SET-PP2A complex in acute myeloid leukemia; SET binding drugs have antagonistic activity
-
Pippa R, Dominguez A, Christensen DJ, Moreno-Miralles I, Blanco-Prieto MJ, et al. 2014. Effect of FTY720 on the SET-PP2A complex in acute myeloid leukemia; SET binding drugs have antagonistic activity. Leukemia 28:1915-18
-
(2014)
Leukemia
, vol.28
, pp. 1915-1918
-
-
Pippa, R.1
Dominguez, A.2
Christensen, D.J.3
Moreno-Miralles, I.4
Blanco-Prieto, M.J.5
-
38
-
-
84899000071
-
SETing OP449 into the PP2A-activating drug family
-
Perrotti D, Neviani R. 2014. SETing OP449 into the PP2A-activating drug family. Clin. Cancer Res. 20:2026-28
-
(2014)
Clin. Cancer Res.
, vol.20
, pp. 2026-2028
-
-
Perrotti, D.1
Neviani, R.2
-
39
-
-
84898936320
-
Antagonism of SET using OP449 enhances the efficacy of tyrosine kinase inhibitors and overcomes drug resistance in myeloid leukemia
-
Agarwal A, MacKenzie RJ, Pippa R, Eide CA, Oddo J, et al. 2014. Antagonism of SET using OP449 enhances the efficacy of tyrosine kinase inhibitors and overcomes drug resistance in myeloid leukemia. Clin. Cancer Res. 20:2092-103
-
(2014)
Clin. Cancer Res.
, vol.20
, pp. 2092-2103
-
-
Agarwal, A.1
MacKenzie, R.J.2
Pippa, R.3
Eide, C.A.4
Oddo, J.5
-
41
-
-
84892858000
-
Integrating virtual and biochemical screening for protein tyrosine phosphatase inhibitor discovery
-
Martin KR, Narang P, Medina-Franco JL, Meurice N, MacKeigan JP. 2014. Integrating virtual and biochemical screening for protein tyrosine phosphatase inhibitor discovery. Methods 15:219-28
-
(2014)
Methods
, vol.15
, pp. 219-228
-
-
Martin, K.R.1
Narang, P.2
Medina-Franco, J.L.3
Meurice, N.4
MacKeigan, J.P.5
-
43
-
-
33847202286
-
Protein tyrosine phosphatase 1B deficiency or inhibition delays ErbB2-induced mammary tumorigenesis and protects from lung metastasis
-
Julien SG, DubéN, ReadM, Penney J, PaquetM, et al. 2007. Protein tyrosine phosphatase 1B deficiency or inhibition delays ErbB2-induced mammary tumorigenesis and protects from lung metastasis. Nat. Genet. 39:338-46
-
(2007)
Nat. Genet.
, vol.39
, pp. 338-346
-
-
Julien, S.G.1
Dubé, N.2
Read, M.3
Penney, J.4
Paquet, M.5
-
44
-
-
84902852963
-
Targeting the disordered C terminus of PTP1B with an allosteric inhibitor
-
Krishnan N, Koveal D, Miller DH, Xue B, Akshinthala SD, et al. 2014. Targeting the disordered C terminus of PTP1B with an allosteric inhibitor. Nat. Chem. Biol. 10:558-66
-
(2014)
Nat. Chem. Biol.
, vol.10
, pp. 558-566
-
-
Krishnan, N.1
Koveal, D.2
Miller, D.H.3
Xue, B.4
Akshinthala, S.D.5
-
45
-
-
84914674462
-
Therapeutic targeting the cell division cycle 25 (CDC25) phosphatases in human acute myeloid leukemia-the possibility to target several kinases through inhibition of the various CDC25 isoforms
-
Brenner AK, Reikvam H, Lavecchia A, Bruserud Ø. 2014. Therapeutic targeting the cell division cycle 25 (CDC25) phosphatases in human acute myeloid leukemia-the possibility to target several kinases through inhibition of the various CDC25 isoforms. Molecules 19(11):18414-47
-
(2014)
Molecules
, vol.19
, Issue.11
, pp. 18414-18447
-
-
Brenner, A.K.1
Reikvam, H.2
Lavecchia, A.3
Bruserud, Ø.4
-
46
-
-
84930081935
-
Synthesis and biological evaluation of 3-aminoisoquinolin-1 2H)-one based inhibitors of the dual-specificity phosphatase Cdc25B
-
Rosenker KMG, Paquette WD, Johnston PA, Sharlow ER, Vogt A, et al. 2015. Synthesis and biological evaluation of 3-aminoisoquinolin-1(2H)-one based inhibitors of the dual-specificity phosphatase Cdc25B. Bioorg. Med. Chem. 23(12):2810-18
-
(2015)
Bioorg. Med. Chem.
, vol.23
, Issue.12
, pp. 2810-2818
-
-
Rosenker, K.M.G.1
Paquette, W.D.2
Johnston, P.A.3
Sharlow, E.R.4
Vogt, A.5
-
47
-
-
84905039727
-
Phosphatase of regenerating liver: A novel target for cancer therapy
-
Campbell AM, Zhang ZY. 2014. Phosphatase of regenerating liver: A novel target for cancer therapy. Expert Opin. Ther. Targets 18:555-69
-
(2014)
Expert Opin. Ther. Targets
, vol.18
, pp. 555-569
-
-
Campbell, A.M.1
Zhang, Z.Y.2
-
48
-
-
84898472215
-
Investigational inhibitors of PTP4A3 phosphatase as antineoplastic agents
-
Sharlow ER, Wipf P, McQueeney KE, Bakan A, Lazo JS. 2014. Investigational inhibitors of PTP4A3 phosphatase as antineoplastic agents. Expert Opin. Investig. Drugs 23:661-73
-
(2014)
Expert Opin. Investig. Drugs
, vol.23
, pp. 661-673
-
-
Sharlow, E.R.1
Wipf, P.2
McQueeney, K.E.3
Bakan, A.4
Lazo, J.S.5
-
49
-
-
80052571556
-
Targeting intracellular oncoproteins with antibody therapy or vaccination
-
Guo K, Li J, Tang JP, Tan CP, Hong CW, et al. 2011. Targeting intracellular oncoproteins with antibody therapy or vaccination. Sci. Transl. Med. 3:99ra85
-
(2011)
Sci. Transl. Med.
, vol.3
, pp. 99ra85
-
-
Guo, K.1
Li, J.2
Tang, J.P.3
Tan, C.P.4
Hong, C.W.5
-
50
-
-
84863788995
-
Engineering the first chimeric antibody in targeting intracellular PRL-3 oncoprotein for cancer therapy in mice
-
Guo K, Tang JP, Jie L, Al-Aidaroos AQ,Hong CW, et al. 2012. Engineering the first chimeric antibody in targeting intracellular PRL-3 oncoprotein for cancer therapy in mice. Oncotarget 3:158-71
-
(2012)
Oncotarget
, vol.3
, pp. 158-171
-
-
Guo, K.1
Tang, J.P.2
Jie, L.3
Al-Aidaroos, A.Q.4
Hong, C.W.5
-
51
-
-
0032904432
-
PTEN: A tumour suppressor that functions as a phospholipid phosphatase
-
Maehama T,Dixon JE. 1999. PTEN: A tumour suppressor that functions as a phospholipid phosphatase. Trends Cell Biol. 9:125-28
-
(1999)
Trends Cell Biol.
, vol.9
, pp. 125-128
-
-
Maehama, T.1
Dixon, J.E.2
-
53
-
-
84903957093
-
Pathological unfoldomics of uncontrolled chaos: Intrinsically disordered proteins and human diseases
-
Uversky VN, Davé V, Iakoucheva LM, Malaney P, Metallo SJ, et al. 2014. Pathological unfoldomics of uncontrolled chaos: intrinsically disordered proteins and human diseases. Chem. Rev. 114:6844-79
-
(2014)
Chem. Rev.
, vol.114
, pp. 6844-6879
-
-
Uversky, V.N.1
Davé, V.2
Iakoucheva, L.M.3
Malaney, P.4
Metallo, S.J.5
-
54
-
-
84895809523
-
Cytotoxic activity of the casein kinase 2 inhibitor CX-4945 against T-cell acute lymphoblastic leukemia: Targeting the unfolded protein response signaling
-
Buontempo F, Orsini E, Martins LR, Antunes I, Lonetti A, et al. 2014. Cytotoxic activity of the casein kinase 2 inhibitor CX-4945 against T-cell acute lymphoblastic leukemia: targeting the unfolded protein response signaling. Leukemia 28:543-53
-
(2014)
Leukemia
, vol.28
, pp. 543-553
-
-
Buontempo, F.1
Orsini, E.2
Martins, L.R.3
Antunes, I.4
Lonetti, A.5
-
55
-
-
84891855786
-
Activity of the clinical-stage CK2-specific inhibitor CX-4945 against chronic lymphocytic leukemia
-
Martins LR, Lúcio P, Melão A, Antunes I, Cardoso BA, et al. 2014. Activity of the clinical-stage CK2-specific inhibitor CX-4945 against chronic lymphocytic leukemia. Leukemia 28:178-82
-
(2014)
Leukemia
, vol.28
, pp. 178-182
-
-
Martins, L.R.1
Ucio P, L.2
Melão, A.3
Antunes, I.4
Cardoso, B.A.5
-
56
-
-
84907879938
-
Small molecules targeting c-Myc oncogene: Promising anti-cancer therapeutics
-
Chen BJ, Wu YL, Tanaka Y, Zhang W. 2014. Small molecules targeting c-Myc oncogene: promising anti-cancer therapeutics. Int. J. Biol. Sci. 10:1084-96
-
(2014)
Int. J. Biol. Sci.
, vol.10
, pp. 1084-1096
-
-
Chen, B.J.1
Wu, Y.L.2
Tanaka, Y.3
Zhang, W.4
-
58
-
-
0142057146
-
Lowmolecular weight inhibitors of Myc-Max interaction and function
-
YinX,Giap C, Lazo JS, Prochownik EV. 2003. Lowmolecular weight inhibitors of Myc-Max interaction and function. Oncogene 22:6151-59
-
(2003)
Oncogene
, vol.22
, pp. 6151-6159
-
-
Yin, X.1
Giap, C.2
Lazo, J.S.3
Prochownik, E.V.4
-
59
-
-
84922394070
-
Therapeutic effects of an anti-Myc drug on mouse pancreatic cancer
-
Stellas D, Szabolcs M, Koul S, Li Z, Polyzos A, et al. 2014. Therapeutic effects of an anti-Myc drug on mouse pancreatic cancer. J. Natl. Cancer Inst. 106:dju320
-
(2014)
J. Natl. Cancer Inst.
, vol.106
, pp. dju320
-
-
Stellas, D.1
Szabolcs, M.2
Koul, S.3
Li, Z.4
Polyzos, A.5
-
60
-
-
79960623998
-
The action mechanism of the Myc inhibitor termed Omomycmay give clues on how to targetMyc for cancer therapy
-
Savino M, Annibali D, Carucci N, Favuzzi E, Cole MD, et al. 2011. The action mechanism of the Myc inhibitor termed Omomycmay give clues on how to targetMyc for cancer therapy. PLOS ONE 6:e22284
-
(2011)
PLOS ONE
, vol.6
, pp. e22284
-
-
Savino, M.1
Annibali, D.2
Carucci, N.3
Favuzzi, E.4
Cole, M.D.5
-
61
-
-
0032511987
-
Design and properties of a Myc derivative that efficiently homodimerizes
-
Soucek L, Helmer-Citterich M, Sacco A, Jucker R, Cesareni G, Nasi S. 1998. Design and properties of a Myc derivative that efficiently homodimerizes. Oncogene 17:2463-72
-
(1998)
Oncogene
, vol.17
, pp. 2463-2472
-
-
Soucek, L.1
Helmer-Citterich, M.2
Sacco, A.3
Jucker, R.4
Cesareni, G.5
Nasi, S.6
-
62
-
-
0037096903
-
Omomyc, a potential Myc dominant negative, enhances Myc-induced apoptosis
-
Soucek L, Jucker R, Panacchia L, Ricordy R, Tato F, Nasi S. 2002. Omomyc, a potential Myc dominant negative, enhances Myc-induced apoptosis. Cancer Res. 62:3507-10
-
(2002)
Cancer Res.
, vol.62
, pp. 3507-3510
-
-
Soucek, L.1
Jucker, R.2
Panacchia, L.3
Ricordy, R.4
Tato, F.5
Nasi, S.6
-
63
-
-
84907303705
-
Myc inhibition is effective against glioma and reveals a role for Myc in proficient mitosis
-
Annibali D, Whitfield JR, Favuzzi E, Jauset T, Serrano E, et al. 2014. Myc inhibition is effective against glioma and reveals a role for Myc in proficient mitosis. Nat. Commun. 5:4632
-
(2014)
Nat. Commun.
, vol.5
, pp. 4632
-
-
Annibali, D.1
Whitfield, J.R.2
Favuzzi, E.3
Jauset, T.4
Serrano, E.5
-
64
-
-
84874835799
-
Inhibition of Myc family proteins eradicates KRas-driven lung cancer in mice
-
Soucek L, Whitfield JR, Sodir NM, Masso-Valles D, Serrano E, et al. 2013. Inhibition of Myc family proteins eradicates KRas-driven lung cancer in mice. Genes Dev. 27:504-13
-
(2013)
Genes Dev.
, vol.27
, pp. 504-513
-
-
Soucek, L.1
Whitfield, J.R.2
Sodir, N.M.3
Masso-Valles, D.4
Serrano, E.5
-
65
-
-
80052955256
-
BET bromodomain inhibition as a therapeutic strategy to target c-Myc
-
Delmore JE, Issa GC, Lemieux ME, Rahl PB, Shi J, et al. 2011. BET bromodomain inhibition as a therapeutic strategy to target c-Myc. Cell 146:904-17
-
(2011)
Cell
, vol.146
, pp. 904-917
-
-
Delmore, J.E.1
Issa, G.C.2
Lemieux, M.E.3
Rahl, P.B.4
Shi, J.5
-
66
-
-
80053651202
-
TargetingMYC dependence in cancer by inhibiting BET bromodomains
-
Mertz JA, Conery AR, Bryant BM, Sandy P, Balasubramanian S, et al. 2011. TargetingMYC dependence in cancer by inhibiting BET bromodomains. PNAS 108:16669-74
-
(2011)
PNAS
, vol.108
, pp. 16669-16674
-
-
Mertz, J.A.1
Conery, A.R.2
Bryant, B.M.3
Sandy, P.4
Balasubramanian, S.5
-
67
-
-
69549124720
-
Stabilizers of theMax homodimer identified in virtual ligand screening inhibit Myc function
-
JiangH, Bower KE, Beuscher IV AE, Zhou B, Bobkov AA, et al. 2009. Stabilizers of theMax homodimer identified in virtual ligand screening inhibit Myc function. Mol. Pharmacol. 76:491-502
-
(2009)
Mol. Pharmacol.
, vol.76
, pp. 491-502
-
-
Jiang, H.1
Bower, K.E.2
Beuscher, I.V.A.E.3
Zhou, B.4
Bobkov, A.A.5
-
69
-
-
84923080118
-
P53 as a target for the treatment of cancer
-
Duffy MJ, Synnott NC, McGowan PM, Crown J, O'Connor D, Gallagher WM. 2014. p53 as a target for the treatment of cancer. Cancer Treat. Rev. 40:1153-60
-
(2014)
Cancer Treat. Rev.
, vol.40
, pp. 1153-1160
-
-
Duffy, M.J.1
Synnott, N.C.2
McGowan, P.M.3
Crown, J.4
O'Connor, D.5
Gallagher, W.M.6
-
71
-
-
70450270900
-
Awakening guardian angels: Drugging the p53 pathway
-
Brown CJ, Lain S, Verma CS, Fersht AR, Lane DP. 2009. Awakening guardian angels: drugging the p53 pathway. Nat. Rev. Cancer 9:862-73
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 862-873
-
-
Brown, C.J.1
Lain, S.2
Verma, C.S.3
Fersht, A.R.4
Lane, D.P.5
-
72
-
-
84896837973
-
Discovery of AMG232, a potent, selective, and orally bioavailable MDM2-p53 inhibitor in clinical development
-
Sun D, Li Z, Rew Y, GribbleM, BartbergerMD, et al. 2014. Discovery of AMG232, a potent, selective, and orally bioavailable MDM2-p53 inhibitor in clinical development. J. Med. Chem. 57:1454-72
-
(2014)
J. Med. Chem.
, vol.57
, pp. 1454-1472
-
-
Sun, D.1
Li, Z.2
Rew, Y.3
Gribble, M.4
Bartberger, M.D.5
-
73
-
-
84908148515
-
SAR405838: An optimized inhibitor of MDM2-p53 interaction that induces complete and durable tumor regression
-
Wang S, Sun W, Zhao Y, McEachern D, Meaux I, et al. 2014. SAR405838: An optimized inhibitor of MDM2-p53 interaction that induces complete and durable tumor regression. Cancer Res. 74:5855-65
-
(2014)
Cancer Res.
, vol.74
, pp. 5855-5865
-
-
Wang, S.1
Sun, W.2
Zhao, Y.3
McEachern, D.4
Meaux, I.5
-
74
-
-
84889578101
-
Small molecule inhibitors of MDM2-p53 andMDMX-p53 interactions as new cancer therapeutics
-
Zhao Y, Bernard D,Wang S. 2013. Small molecule inhibitors of MDM2-p53 andMDMX-p53 interactions as new cancer therapeutics. BioDiscovery 8:4
-
(2013)
BioDiscovery
, vol.8
, pp. 4
-
-
Zhao, Y.1
Bernard, D.2
Wang, S.3
-
75
-
-
84877095601
-
Molecular pathways: JAK/STAT pathway: Mutations, inhibitors, and resistance
-
Quintás-Cardama A, Verstovsek S. 2013. Molecular pathways: JAK/STAT pathway: mutations, inhibitors, and resistance. Clin. Cancer Res. 19:1933-40
-
(2013)
Clin. Cancer Res.
, vol.19
, pp. 1933-1940
-
-
Quintás-Cardama, A.1
Verstovsek, S.2
-
76
-
-
84896698541
-
High content pSTAT3/1 imaging assays to screen for selective inhibitors of STAT3 pathway activation in head and neck cancer cell lines
-
Johnston PA, SenM,Hua Y, Camarco D, Shun TY, et al. 2014. High content pSTAT3/1 imaging assays to screen for selective inhibitors of STAT3 pathway activation in head and neck cancer cell lines. Assay Drug Dev. Technol. 12:55-79
-
(2014)
Assay Drug Dev. Technol.
, vol.12
, pp. 55-79
-
-
Johnston, P.A.1
Sen, M.2
Hua, Y.3
Camarco, D.4
Shun, T.Y.5
-
77
-
-
84908012116
-
2-Guanidinoquinazolines as new inhibitors of the STAT3 pathway
-
LaPorte MG, da Paz Lima DJ, Zhang F, Sen M, Grandis JR, et al. 2014. 2-Guanidinoquinazolines as new inhibitors of the STAT3 pathway. Bioorg. Med. Chem. Lett. 24:5081-85
-
(2014)
Bioorg. Med. Chem. Lett.
, vol.24
, pp. 5081-5085
-
-
LaPorte, M.G.1
Da Paz Lima, D.J.2
Zhang, F.3
Sen, M.4
Grandis, J.R.5
-
78
-
-
84902169125
-
Galiellalactone is a direct inhibitor of the transcription factor STAT3 in prostate cancer cells
-
Don-Doncow N, Escobar Z, JohanssonM, Kjellström S, Garcia V, et al. 2014. Galiellalactone is a direct inhibitor of the transcription factor STAT3 in prostate cancer cells. J. Biol. Chem. 289:15969-78
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 15969-15978
-
-
Don-Doncow, N.1
Escobar, Z.2
Johansson, M.3
Kjellström, S.4
Garcia, V.5
-
79
-
-
39449098191
-
Galiellalactone is a novel therapeutic candidate against hormone-refractory prostate cancer expressing activated Stat3
-
Hellsten R, Johansson M, Dahlman A, Dizeyi N, Sterner O, Bjartell A. 2008. Galiellalactone is a novel therapeutic candidate against hormone-refractory prostate cancer expressing activated Stat3. Prostate 68:269-80
-
(2008)
Prostate
, vol.68
, pp. 269-280
-
-
Hellsten, R.1
Johansson, M.2
Dahlman, A.3
Dizeyi, N.4
Sterner, O.5
Bjartell, A.6
-
80
-
-
84902171852
-
Allosteric inhibitors of the Eya2 phosphatase are selective and inhibit Eya2-mediated cell migration
-
Krueger AB, Drasin D, Lea WA, Patrick AN, Patnaik S, et al. 2014. Allosteric inhibitors of the Eya2 phosphatase are selective and inhibit Eya2-mediated cell migration. J. Biol. Chem. 289:16349-61
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 16349-16361
-
-
Krueger, A.B.1
Drasin, D.2
Lea, W.A.3
Patrick, A.N.4
Patnaik, S.5
-
81
-
-
84871566520
-
Identification of a selective small-molecule inhibitor series targeting the eyes absent 2 (Eya2) phosphatase activity
-
Krueger AB, Dehdashti SJ, Southall N, Marugan JJ, Ferrer M, et al. 2013. Identification of a selective small-molecule inhibitor series targeting the eyes absent 2 (Eya2) phosphatase activity. J. Biomol. Screen. 18:85-96
-
(2013)
J. Biomol. Screen.
, vol.18
, pp. 85-96
-
-
Krueger, A.B.1
Dehdashti, S.J.2
Southall, N.3
Marugan, J.J.4
Ferrer, M.5
-
82
-
-
84922949970
-
Chemical biology. A small-molecule inhibitor of the aberrant transcription factor CBF-SMMHC delays leukemia in mice
-
Illendula A, Pulikkan JA, Zong H, Grembecka J, Xue L, et al. 2015. Chemical biology. A small-molecule inhibitor of the aberrant transcription factor CBF-SMMHC delays leukemia in mice. Science 347:779-84
-
(2015)
Science
, vol.347
, pp. 779-784
-
-
Illendula, A.1
Pulikkan, J.A.2
Zong, H.3
Grembecka, J.4
Xue, L.5
-
83
-
-
84908491115
-
Drugging the undruggable RAS: Mission possible
-
Cox AD, Fesik SW, Kimmelman AC, Luo J, Der CJ. 2014. Drugging the undruggable RAS: mission possible? Nat. Rev. Drug Discov. 13:828-51
-
(2014)
Nat. Rev. Drug Discov.
, vol.13
, pp. 828-851
-
-
Cox, A.D.1
Fesik, S.W.2
Kimmelman, A.C.3
Luo, J.4
Der, C.J.5
-
84
-
-
84886745490
-
US National Cancer Institute's new RAS project targets an old foe
-
Thompson H. 2013. US National Cancer Institute's new RAS project targets an old foe. Nat. Med. 19:949-50
-
(2013)
Nat. Med.
, vol.19
, pp. 949-950
-
-
Thompson, H.1
-
85
-
-
0033614962
-
Essential role for oncogenic Ras in tumour maintenance
-
Chin L, Tam A, Pomerantz J, Wong M, Holash J, et al. 1998. Essential role for oncogenic Ras in tumour maintenance. Nature 400:468-72
-
(1998)
Nature
, vol.400
, pp. 468-472
-
-
Chin, L.1
Tam, A.2
Pomerantz, J.3
Wong, M.4
Holash, J.5
-
86
-
-
84859463451
-
Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity
-
Maurer T, Garrenton LS, Oh A, Pitts K, Anderson DJ, et al. 2012. Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity. PNAS 109:5299-304
-
(2012)
PNAS
, vol.109
, pp. 5299-5304
-
-
Maurer, T.1
Garrenton, L.S.2
Oh, A.3
Pitts, K.4
Anderson, D.J.5
-
87
-
-
84887521253
-
Transformation by Hras(G12V) is consistently associated with mutant allele copy gains and is reversed by farnesyl transferase inhibition
-
Chen X, Makarewicz JM, Knauf JA, Johnson LK, Fagin JA. 2014. Transformation by Hras(G12V) is consistently associated with mutant allele copy gains and is reversed by farnesyl transferase inhibition. Oncogene 33:5442-49
-
(2014)
Oncogene
, vol.33
, pp. 5442-5449
-
-
Chen, X.1
Makarewicz, J.M.2
Knauf, J.A.3
Johnson, L.K.4
Fagin, J.A.5
-
88
-
-
78649487698
-
RAS superfamily GEFs and GAPs: Validated and tractable targets for cancer therapy
-
Vigil D, Cherfils J,RossmanKL, DerCJ. 2010. RAS superfamily GEFs and GAPs: validated and tractable targets for cancer therapy? Nat. Rev. Cancer 10:842-57
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 842-857
-
-
Vigil, D.1
Cherfils, J.2
Rossman, K.L.3
Der, C.J.4
-
89
-
-
84875534210
-
Integrated preclinical and clinical development of S-trans, trans-farnesylthiosalicylic acid (FTS, Salirasib) in pancreatic cancer
-
Laheru D, Shah P, Rajeshkumar NV, McAllister F, Taylor G, et al. 2010. Integrated preclinical and clinical development of S-trans, trans-farnesylthiosalicylic acid (FTS, Salirasib) in pancreatic cancer. Investig. New Drugs 30:3291-99
-
(2010)
Investig. New Drugs
, vol.30
, pp. 3291-3299
-
-
Laheru, D.1
Shah, P.2
Rajeshkumar, N.V.3
McAllister, F.4
Taylor, G.5
-
90
-
-
84894414494
-
Small-molecule control of intracellular protein levels throughmodulation of the ubiquitin proteasome system
-
CrewsCM, Buckley DL. 2014. Small-molecule control of intracellular protein levels throughmodulation of the ubiquitin proteasome system. Angew. Chem. Int. Ed. Engl. 53:2313-30
-
(2014)
Angew. Chem. Int. Ed. Engl.
, vol.53
, pp. 2313-2330
-
-
Crews, C.M.1
Buckley, D.L.2
-
91
-
-
84920590896
-
Pharmacological targeting of the pseudokinase Her3
-
Xie T, Lim SM, Westover KD, Dodge ME, Ercan D, et al. 2014. Pharmacological targeting of the pseudokinase Her3. Nat. Chem. Biol. 10:1006-12
-
(2014)
Nat. Chem. Biol.
, vol.10
, pp. 1006-1012
-
-
Xie, T.1
Lim, S.M.2
Westover, K.D.3
Dodge, M.E.4
Ercan, D.5
-
92
-
-
52749097713
-
Characterization of the active site and a unique uncompetitive inhibitor of the PPM1-type protein phosphatase PPM1D
-
Chuman Y, Yagi H, Fukuda T, Nomura T, Matsukizono M, et al. 2008. Characterization of the active site and a unique uncompetitive inhibitor of the PPM1-type protein phosphatase PPM1D. Protein Pept. Lett. 15:938-48
-
(2008)
Protein Pept. Lett.
, vol.15
, pp. 938-948
-
-
Chuman, Y.1
Yagi, H.2
Fukuda, T.3
Nomura, T.4
Matsukizono, M.5
-
93
-
-
79957864490
-
Overexpression and small molecule-triggered downregulation of CIP2A in lung cancer
-
Liang Ma L, Wen Z-S, Liu Z, Hu Z, Ma J, et al. 2011. Overexpression and small molecule-triggered downregulation of CIP2A in lung cancer. PLOS ONE 6(5):e20159
-
(2011)
PLOS ONE
, vol.6
, Issue.5
, pp. e20159
-
-
Liang Ma, L.1
Wen, Z.-S.2
Liu, Z.3
Hu, Z.4
Ma, J.5
-
94
-
-
84904003955
-
PP2A inhibition is a common event in colorectal cancer and its restoration using FTY720 shows promising therapeutic potential
-
Cristobal I,Manso R, Rincón R, Caramés C, Senin C, et al. 2014. PP2A inhibition is a common event in colorectal cancer and its restoration using FTY720 shows promising therapeutic potential. Mol. Cancer Ther. 13:938-47
-
(2014)
Mol. Cancer Ther.
, vol.13
, pp. 938-947
-
-
Cristobal, I.1
Manso, R.2
Rincón, R.3
Caramés, C.4
Senin, C.5
-
95
-
-
70349312573
-
Structure-activity relationship studies of fostriecin, cytostatin, and key analogs, with PP1, PP2A, PP5, and (12-13)-chimeras (PP1/PP2A and PP5/PP2A), provide further insight into the inhibitory actions of fostriecin family inhibitors
-
Swingle MR, Amable L, Lawhorn BG, Buck SB, Burke CP, et al. 2009. Structure-activity relationship studies of fostriecin, cytostatin, and key analogs, with PP1, PP2A, PP5, and (12-13)-chimeras (PP1/PP2A and PP5/PP2A), provide further insight into the inhibitory actions of fostriecin family inhibitors. J. Pharmacol. Exp. Ther. 331:45-53
-
(2009)
J. Pharmacol. Exp. Ther.
, vol.331
, pp. 45-53
-
-
Swingle, M.R.1
Amable, L.2
Lawhorn, B.G.3
Buck, S.B.4
Burke, C.P.5
-
96
-
-
77949853380
-
Salicylic acid based small molecule inhibitor for the oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2)
-
Zhang X, He Y, Liu S, Yu Z, Jiang Z-X, et al. 2010. Salicylic acid based small molecule inhibitor for the oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2). J. Med. Chem. 53:2482-93
-
(2010)
J. Med. Chem.
, vol.53
, pp. 2482-2493
-
-
Zhang, X.1
He, Y.2
Liu, S.3
Yu, Z.4
Jiang, Z.-X.5
-
97
-
-
84906080682
-
Therapeutic potential of targeting the oncogenic SHP2 phosphatase
-
Zeng L-F, Zhang R-Y, Yu Z-H, Sijiu Li, Wu L, et al. 2014. Therapeutic potential of targeting the oncogenic SHP2 phosphatase. J. Med. Chem. 57:6594-609
-
(2014)
J. Med. Chem.
, vol.57
, pp. 6594-6609
-
-
Zeng, L.-F.1
Zhang, R.-Y.2
Yu, Z.-H.3
Li, S.4
Wu, L.5
-
98
-
-
76749161886
-
Inhibition of receptor tyrosine kinase signalling by small molecule agonist of T-cell protein tyrosine phosphatase
-
Mattila E, Marttila H, Sahlberg N, Kohonen P, Tähtinen S, et al. 2010. Inhibition of receptor tyrosine kinase signalling by small molecule agonist of T-cell protein tyrosine phosphatase. BMC Cancer 10:7
-
(2010)
BMC Cancer
, vol.10
, pp. 7
-
-
Mattila, E.1
Marttila, H.2
Sahlberg, N.3
Kohonen, P.4
Tähtinen, S.5
-
99
-
-
39449127662
-
A selective phosphatase of regenerating liver phosphatase inhibitor suppresses tumor cell anchorage-independent growth by a novel mechanism involving p130Cas cleavage
-
Daouti S, LiWH, Qian H, Huang KS, Holmgren J, et al. 2008. A selective phosphatase of regenerating liver phosphatase inhibitor suppresses tumor cell anchorage-independent growth by a novel mechanism involving p130Cas cleavage. Cancer Res. 68:1162-69
-
(2008)
Cancer Res.
, vol.68
, pp. 1162-1169
-
-
Daouti, S.1
Li, W.H.2
Qian, H.3
Huang, K.S.4
Holmgren, J.5
-
100
-
-
84878892275
-
Rhodanine-based PRL-3 inhibitors blocked the migration and invasion of metastatic cancer cells
-
Min G, Lee SK, Kim HN, Han YM, Lee RH, et al. 2013. Rhodanine-based PRL-3 inhibitors blocked the migration and invasion of metastatic cancer cells. Bioorg. Med. Chem. Lett. 23:3769-74
-
(2013)
Bioorg. Med. Chem. Lett.
, vol.23
, pp. 3769-3774
-
-
Min, G.1
Lee, S.K.2
Kim, H.N.3
Han, Y.M.4
Lee, R.H.5
-
101
-
-
84880544411
-
Discovery of PTPRJ agonist peptides that effectively inhibit in vitro cancer cell proliferation and tube formation
-
Ortuso F, Paduano F, Carotenuto A, Gomez-Monterrey I, Bilotta A, et al. 2013. Discovery of PTPRJ agonist peptides that effectively inhibit in vitro cancer cell proliferation and tube formation. ACS Chem. Biol. 8:1497-506
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(2013)
ACS Chem. Biol.
, vol.8
, pp. 1497-1506
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Ortuso, F.1
Paduano, F.2
Carotenuto, A.3
Gomez-Monterrey, I.4
Bilotta, A.5
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