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Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 1, 2012, Pages 729-732

A small molecule inhibitor of p53-inducible protein phosphatase PPM1D

(8) Yagi, Hiroaki a Chuman, Yoshiro a Kozakai, Yuuki a Imagawa, Toshiaki a Takahashi, Yu a Yoshimura, Fumihiko a Tanino, Keiji a Sakaguchi, Kazuyasu a

a HOKKAIDO UNIVERSITY (Japan)

Author keywords

Anti tumor agent; Apoptosis; Dephosphorylation; Inhibitor; Phosphatase

Indexed keywords

ANTINEOPLASTIC AGENT; ENZYME INHIBITOR; PROTEIN P53; PROTEIN PPM1D; SERINE; SPI 001; THREONINE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; CELL PROLIFERATION; DOSE RESPONSE; DRUG ACTIVITY; DRUG SPECIFICITY; ENZYME ACTIVITY; ENZYME INHIBITION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; PROTEIN PHOSPHORYLATION; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL PROLIFERATION; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INDOLES; INHIBITORY CONCENTRATION 50; MODELS, CHEMICAL; NEOPLASMS; PHENANTHRENES; PHOSPHOPROTEIN PHOSPHATASES; PHOSPHORIC MONOESTER HYDROLASES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS PP60(C-SRC); TIME FACTORS; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 84655169159 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2011.10.084 Document Type: Article

Times cited : (37)

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