Pharmacological targeting of the pseudokinase Her3

Nature chemical biology

Volumn 10, Issue 12, 2014, Pages 1006-1012

  Xie, Ting ^a   Lim, Sang M in ^a   Westover, Kenneth D ^a   Dodge, Michael E ^a   Ercan, Dalia ^a   Ficarro, Scott B ^a   Udayakumar, Durga ^a   Gurbani, Deepak ^a   Tae, Hyun S eop ^a   Riddle, Steven M ^a   Sim, Taebo ^a   Marto, Jarrod A ^a   Jänne, Pasi A ^a   Crews, Craig M ^a   Gray, Nathanael S ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACRYLAMIDE DERIVATIVE; ADAMANTANE; ADENINE; ADENOSINE TRIPHOSPHATE; ANTINEOPLASTIC AGENT; CYSTEINE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR 3; ERBB2 PROTEIN, HUMAN; ERBB3 PROTEIN, HUMAN; PROTEIN KINASE INHIBITOR; SCATTER FACTOR RECEPTOR; TX1-85-1;

ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; CELL PROLIFERATION; CHEMICAL PHENOMENA; CHEMISTRY; DRUG EFFECTS; ENZYME ACTIVE SITE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; MOLECULAR DOCKING; MOLECULARLY TARGETED THERAPY; PROTEIN DEGRADATION; PROTEIN MULTIMERIZATION; SIGNAL TRANSDUCTION; SYNTHESIS; TUMOR CELL LINE;

ACRYLAMIDES; ADAMANTANE; ADENINE; ADENOSINE TRIPHOSPHATE; ANTINEOPLASTIC AGENTS; CATALYTIC DOMAIN; CELL LINE, TUMOR; CELL PROLIFERATION; CYSTEINE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MOLECULAR DOCKING SIMULATION; MOLECULAR TARGETED THERAPY; PROTEIN KINASE INHIBITORS; PROTEIN MULTIMERIZATION; PROTEOLYSIS; PROTO-ONCOGENE PROTEINS C-MET; RECEPTOR, ERBB-2; RECEPTOR, ERBB-3; SIGNAL TRANSDUCTION;

EID: 84920590896     PISSN: None     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.1658     Document Type: Article

References (0)