Rhodanine-based PRL-3 inhibitors blocked the migration and invasion of metastatic cancer cells

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 13, 2013, Pages 3769-3774

  Min, Garam ^a   Lee, Su Kyung ^a   Kim, Hye Nan ^a   Han, Young Min ^a   Lee, Rhan Hee ^a   Jeong, Dae Gwin ^a   Han, Dong Cho ^a   Kwon, Byoung Mog ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

Invasion; Metastasis; Migration; PRL 3; Rhodanine

Indexed keywords

BR 1; CG 707; CYTOKERATIN 8; PHOSPHATASE; PRL 3 PHOSPHATASE; RHODANINE; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CELL MIGRATION; COLON CANCER; CYTOTOXICITY; ENZYME ACTIVITY; EPITHELIAL MESENCHYMAL TRANSITION; IC 50; METASTASIS; PROTEIN PHOSPHORYLATION; SYNTHESIS; TUMOR INVASION;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME INHIBITORS; HUMANS; MOLECULAR STRUCTURE; NEOPLASM PROTEINS; PROTEIN TYROSINE PHOSPHATASES; RHODANINE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84878892275     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2013.04.092     Document Type: Article

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