Phosphatase of regenerating liver: A novel target for cancer therapy

Expert Opinion on Therapeutic Targets

Volumn 18, Issue 5, 2014, Pages 555-569

  Campbell, Amanda M ^a,b   Zhang, Zhong Yin ^a,b,c,d,e  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PURDUE UNIVERSITY   (United States)

^c NANKAI UNIVERSITY   (China)

^d PFIZER INC   (United States)

^e UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Adhesion junctions; Adhesion molecules; Cell migration; Colorectal cancer; De trimerization; Epithelial to mesenchymal transition; Extracellular signal regulated kinases 1 and 2; Filamentous actin dynamics; Monoclonal antibody targeting; Phosphatase and tensin homologue deleted on chromosome 10; Phosphatase of regenerating liver; PI3K Akt; Receptor tyrosine kinases; Small molecule inhibition; Src kinase

Indexed keywords

ALPHA INTEGRIN; BETA INTEGRIN; HISTONE DEACETYLASE 4; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PLAKOGLOBIN; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN KINASE B; PROTEIN MCL 1; PROTEIN P53; STAT3 PROTEIN; STAT5 PROTEIN; TRANSCRIPTION FACTOR SNAIL; UVOMORULIN; VINCULIN; CELL CYCLE PROTEIN; MEMBRANE PROTEIN; ONCOPROTEIN; PROTEIN TYROSINE PHOSPHATASE; PTP4A1 PROTEIN, HUMAN; PTP4A2 PROTEIN, HUMAN; PTP4A3 PROTEIN, HUMAN; TUMOR PROTEIN; TUMOR SUPPRESSOR PROTEIN;

ACTIN FILAMENT; ACUTE GRANULOCYTIC LEUKEMIA; BREAST CANCER; CANCER PROGNOSIS; CANCER THERAPY; CELL FUNCTION; CELLULAR DISTRIBUTION; COLORECTAL CANCER; DRUG TARGETING; ESOPHAGUS CANCER; HUMAN; LIVER CANCER; LIVER REGENERATION; LUNG CANCER; METASTASIS; MOUTH CANCER; NASOPHARYNX CANCER; NONHUMAN; ONCOGENE; ONCOGENE C FOS; OVARY CANCER; PHOSPHATASE OF REGENERATING LIVER; PRENYLATION; PROTEIN EXPRESSION; PROTEIN INTERACTION; REVIEW; STOMACH CARCINOMA; TUMOR SUPPRESSOR GENE; UPREGULATION; UTERINE CERVIX CANCER; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL COMPARTMENTALIZATION; CELL DIVISION; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; ENZYME INDUCTION; ENZYMOLOGY; LIVER; MOLECULARLY TARGETED THERAPY; MOUSE; NEOPLASM; PHYSIOLOGY; PROTEIN CONFORMATION; PROTEIN MOTIF; SIGNAL TRANSDUCTION; TUMOR INVASION;

AMINO ACID MOTIFS; ANIMALS; CELL COMPARTMENTATION; CELL CYCLE PROTEINS; CELL DIVISION; ENZYME INDUCTION; HUMANS; LIVER; MEMBRANE PROTEINS; MICE; MODELS, MOLECULAR; MOLECULAR TARGETED THERAPY; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NEOPLASM PROTEINS; NEOPLASMS; ONCOGENE PROTEINS; PROTEIN CONFORMATION; PROTEIN TYROSINE PHOSPHATASES; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS;

EID: 84905039727     PISSN: 14728222     EISSN: 17447631     Source Type: Journal    
DOI: 10.1517/14728222.2014.892926     Document Type: Review

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