Hair Cell Loss Induced by Sphingosine and a Sphingosine Kinase Inhibitor in the Rat Cochlea

Neurotoxicity Research

Volumn 29, Issue 1, 2016, Pages 35-46

  Tani, Kohsuke ^a   Tabuchi, Keiji ^a   Hara, Akira ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

Cisplatin; Cochlea; Cochlear hair cell; Sphingosine; Sphingosine kinase

Indexed keywords

2 (4 HYDROXYANILINO) 4 (4 CHLOROPHENYL)THIAZOLE; CASPASE 3; CISPLATIN; PROTEIN INHIBITOR; SPHINGOSINE; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE KINASE; UNCLASSIFIED DRUG; ENZYME INHIBITOR; PHOSPHOTRANSFERASE;

ADULT; ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL LOSS; COCHLEA; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORTI ORGAN; ENZYME ACTIVATION; ENZYME ACTIVITY; FEMALE; HAIR CELL; IMMUNOHISTOCHEMISTRY; NONHUMAN; OTOTOXICITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; WESTERN BLOTTING; ANALYSIS OF VARIANCE; ANIMAL; COCHLEAR HAIR CELL; CYTOLOGY; DOSE RESPONSE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; IN VITRO STUDY; METABOLISM; NEWBORN; ORGAN CULTURE TECHNIQUE; SPRAGUE DAWLEY RAT; TIME FACTOR;

ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; CASPASE 3; CISPLATIN; COCHLEA; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; HAIR CELLS, AUDITORY; IN VITRO TECHNIQUES; ORGAN CULTURE TECHNIQUES; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); RATS; RATS, SPRAGUE-DAWLEY; SPHINGOSINE; TIME FACTORS;

EID: 84953352351     PISSN: 10298428     EISSN: 14763524     Source Type: Journal    
DOI: 10.1007/s12640-015-9563-7     Document Type: Article

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