Estradiol protects the cochlea against gentamicin ototoxicity through inhibition of the JNK pathway

Hearing Research

Volumn 261, Issue 1-2, 2010, Pages 67-74

  Nakamagoe, Mariko ^a   Tabuchi, Keiji ^a   Uemaetomari, Isao ^a   Nishimura, Bungo ^a   Hara, Akira ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

17 Estradiol (E2); c jun N terminal kinase (JNK); Gentamicin; Hair cell; Organ of Corti

Indexed keywords

ESTRADIOL; GENTAMICIN; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CELL LOSS; COCHLEA; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORTI ORGAN; DRUG EXPOSURE; EAR PROTECTION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; EXPLANT; HAIR CELL; NICK END LABELING; NONHUMAN; OTOTOXICITY; PRIORITY JOURNAL; RAT; TISSUE CULTURE;

ANIMALS; ANTI-BACTERIAL AGENTS; APOPTOSIS; CASPASES; CELLS, CULTURED; COCHLEA; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTRADIOL; GENTAMICINS; HAIR CELLS, AUDITORY; MAP KINASE KINASE 4; MODELS, ANIMAL; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION;

EID: 76949106033     PISSN: 03785955     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.heares.2010.01.004     Document Type: Article

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