Sphingosine induces apoptosis in hippocampal neurons and astrocytes by activating caspase-3/-9 via a mitochondrial pathway linked to SDK/14-3-3 protein/Bax/cytochrome c

Journal of Cellular Physiology

Volumn 226, Issue 9, 2011, Pages 2329-2337

  Kanno, Takeshi ^a   Nishizaki, Tomoyuki ^a  

^a HYOGO COLLEGE OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 9; CYTOCHROME C; PROTEIN 14 3 3; PROTEIN BAX; PROTEIN KINASE C DELTA; ROTTLERIN; SPHINGOSINE; SPHINGOSINE DEPENDENT PROTEIN KINASE; SPHINGOSINE KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL CELL CULTURE; APOPTOSIS; ARTICLE; ASTROCYTE; BRAIN NERVE CELL; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; DISSOCIATION; ENZYME ACTIVATION; HIPPOCAMPUS; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; RAT;

14-3-3 PROTEINS; ANIMALS; APOPTOSIS; ASTROCYTES; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CASPASE 9; CELLS, CULTURED; CYTOCHROMES C; ENZYME ACTIVATION; HIPPOCAMPUS; INTRACELLULAR SPACE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; NEURONS; PHOSPHORYLATION; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTEIN KINASE C-DELTA; PROTEIN MULTIMERIZATION; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; SPHINGOSINE; THIAZOLES;

RATTUS;

EID: 79958742177     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.22571     Document Type: Article

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