Ceramide/sphingomyelin cycle involvement in gentamicin-induced cochlear hair cell death

Archives of Toxicology

Volumn 89, Issue 3, 2015, Pages 415-421

  Chi, Le Nguyen Uyen ^a,b   Tabuchi, Keiji ^a   Nakamagoe, Mariko ^a   Nakayama, Masahiro ^a   Nishimura, Bungo ^a   Hara, Akira ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b UNIVERSITY OF MEDICINE AND PHARMACY AT HO CHI MINH CITY   (Viet Nam)

Author keywords

Ceramide sphingomyelin cycle; De novo ceramide biosynthesis; Gentamicin

Indexed keywords

2-HYDROXYOLEIC ACID; 3,3' (1,4 PHENYLENE)BIS[N [4 (4,5 DIHYDRO 1H IMIDAZOL 2 YL)PHENYL]ACRYLAMIDE]; ANILINE DERIVATIVE; BENZYLIDENE DERIVATIVE; CERAMIDE; GENTAMICIN; MONOUNSATURATED FATTY ACID; OLEIC ACID; PHOSPHATIDYLCHOLINE-CERAMIDE PHOSPHOCHOLINE TRANSFERASE; PHOSPHOTRANSFERASE; SERINE PALMITOYLTRANSFERASE; SPHINGOMYELIN; SPHINGOMYELIN PHOSPHODIESTERASE; THERMOZYMOCIDIN;

ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CELL CULTURE; CELL DEATH; DRUG EFFECTS; ENZYMOLOGY; HAIR CELL; METABOLISM; NEWBORN; PATHOLOGY; SPRAGUE DAWLEY RAT;

ANILINE COMPOUNDS; ANIMALS; ANIMALS, NEWBORN; BENZYLIDENE COMPOUNDS; CELL DEATH; CELLS, CULTURED; CERAMIDES; FATTY ACIDS, MONOUNSATURATED; GENTAMICINS; HAIR CELLS, AUDITORY; OLEIC ACIDS; RATS, SPRAGUE-DAWLEY; SERINE C-PALMITOYLTRANSFERASE; SPHINGOMYELIN PHOSPHODIESTERASE; SPHINGOMYELINS; TRANSFERASES (OTHER SUBSTITUTED PHOSPHATE GROUPS);

EID: 84939885251     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-014-1259-x     Document Type: Article

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