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Volumn , Issue , 2014, Pages 278-292

Bipolar disorder

Author keywords

[No Author keywords available]

Indexed keywords


EID: 84953258493     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/CBO9781107360556     Document Type: Chapter
Times cited : (1)

References (179)
  • 1
    • 70350154913 scopus 로고    scopus 로고
    • Knockout mice in understanding the mechanism of action of lithium
    • Agam, G., Bersudsky, Y., Berry, G. T., et al. (2009) Knockout mice in understanding the mechanism of action of lithium. Biochem Soc Trans 37: 1121-1125.
    • (2009) Biochem Soc Trans , vol.37 , pp. 1121-1125
    • Agam, G.1    Bersudsky, Y.2    Berry, G.T.3
  • 2
    • 77950575478 scopus 로고    scopus 로고
    • Mitochondrial complex I activity and oxidative damage to mitochondrial proteins in the prefrontal cortex of patients with bipolar disorder
    • Andreazza, A. C., Shao, L., Wang, J. F., and Young, L. T. (2010) Mitochondrial complex I activity and oxidative damage to mitochondrial proteins in the prefrontal cortex of patients with bipolar disorder. Arch Gen Psychiatry 67: 360-368.
    • (2010) Arch Gen Psychiatry , vol.67 , pp. 360-368
    • Andreazza, A.C.1    Shao, L.2    Wang, J.F.3    Young, L.T.4
  • 4
    • 3142676375 scopus 로고    scopus 로고
    • Thedopamine D4 receptor is essential for hyperactivity and impaired behavioral inhibition in a mouse model of attention deicit/hyperactivity disorder
    • Avale, M. E., Falzone, T. L., Gelman, D. M., et al. (2004) Thedopamine D4 receptor is essential for hyperactivity and impaired behavioral inhibition in a mouse model of attention deicit/hyperactivity disorder. Mol Psychiatry 9: 718-726.
    • (2004) Mol Psychiatry , vol.9 , pp. 718-726
    • Avale, M.E.1    Falzone, T.L.2    Gelman, D.M.3
  • 5
    • 25844452847 scopus 로고    scopus 로고
    • Mood stabilizers target cellular plasticity and resilience cascades: Implications for the development of novel therapeutics
    • Bachmann, R. F., Schloesser, R. J., Gould, T. D., and Manji, H. K. (2005) Mood stabilizers target cellular plasticity and resilience cascades: Implications for the development of novel therapeutics. Mol Neurobiol 32: 173-202.
    • (2005) Mol Neurobiol , vol.32 , pp. 173-202
    • Bachmann, R.F.1    Schloesser, R.J.2    Gould, T.D.3    Manji, H.K.4
  • 6
    • 2342451962 scopus 로고    scopus 로고
    • Antipsychotic drugs clozapine and olanzapine upregulate bcl-2 mRNA and protein in rat frontal cortex and hippocampus
    • Bai, O., Zhang, H., and Li, X. M. (2004) Antipsychotic drugs clozapine and olanzapine upregulate bcl-2 mRNA and protein in rat frontal cortex and hippocampus. Brain Res 1010: 81-86.
    • (2004) Brain Res , vol.1010 , pp. 81-86
    • Bai, O.1    Zhang, H.2    Li, X.M.3
  • 7
    • 73249141575 scopus 로고    scopus 로고
    • Anti-depressant and anxiolytic like behaviors in PKCI/HINT1 knockout mice associated with elevated plasma corticosterone level
    • Barbier, E. and Wang, J. B. (2009) Anti-depressant and anxiolytic like behaviors in PKCI/HINT1 knockout mice associated with elevated plasma corticosterone level. BMC Neurosci 10: 132.
    • (2009) BMC Neurosci , vol.10 , pp. 132
    • Barbier, E.1    Wang, J.B.2
  • 8
    • 84255190041 scopus 로고    scopus 로고
    • A role for Akt and glycogen synthase kinase-3 as integrators of dopamine and serotonin neurotransmission in mental health
    • Beaulieu, J. M. (2012) A role for Akt and glycogen synthase kinase-3 as integrators of dopamine and serotonin neurotransmission in mental health. J Psychiatry Neurosci 37: 7-16.
    • (2012) J Psychiatry Neurosci , vol.37 , pp. 7-16
    • Beaulieu, J.M.1
  • 9
    • 0035015950 scopus 로고    scopus 로고
    • Thelifetime cost of bipolar disorder in the US: An estimate for new cases in 1998
    • Begley, C. E., Annegers, J. F., Swann, A. C., et al. (2001) Thelifetime cost of bipolar disorder in the US: An estimate for new cases in 1998. Pharmacoeconomics 19: 483-495.
    • (2001) Pharmacoeconomics , vol.19 , pp. 483-495
    • Begley, C.E.1    Annegers, J.F.2    Swann, A.C.3
  • 10
    • 79960836822 scopus 로고    scopus 로고
    • Cocaine supersensitivity and enhanced motivation for reward in mice lacking dopamine D2 autoreceptors
    • Bello, E. P., Mateo, Y., Gelman, D. M., et al. (2011) Cocaine supersensitivity and enhanced motivation for reward in mice lacking dopamine D2 autoreceptors. Nat Neurosci 14: 1033-1038.
    • (2011) Nat Neurosci , vol.14 , pp. 1033-1038
    • Bello, E.P.1    Mateo, Y.2    Gelman, D.M.3
  • 11
    • 0025344355 scopus 로고
    • Role of inositol-1-phosphatase inhibition in the mechanism of action of lithium
    • Belmaker, R. H., Livne, A., Agam, G., et al. (1990) Role of inositol-1-phosphatase inhibition in the mechanism of action of lithium. Pharmacol Toxicol 66: 76-83.
    • (1990) Pharmacol Toxicol , vol.66 , pp. 76-83
    • Belmaker, R.H.1    Livne, A.2    Agam, G.3
  • 12
    • 0026470454 scopus 로고
    • Inositol passes the blood brain behavior suiciently to reverse lithium Effects on behavior in rats
    • Belmaker, R. H., Revazov, A., Bersudskey, Y., and Kofman, O. (1992) Inositol passes the blood brain behavior suiciently to reverse lithium Effects on behavior in rats. Clin Neuropharmacol 15: 606A-607A.
    • (1992) Clin Neuropharmacol , vol.15 , pp. 606A-607A
    • Belmaker, R.H.1    Revazov, A.2    Bersudskey, Y.3    Kofman, O.4
  • 13
    • 0034777448 scopus 로고    scopus 로고
    • Sleep phase advance and lithium to sustain the antidepressant efect of total sleep deprivation in bipolar depression: New indings supporting the internal coincidence model?
    • Benedetti, F., Barbini, B., Campori, E., et al. (2001) Sleep phase advance and lithium to sustain the antidepressant efect of total sleep deprivation in bipolar depression: New indings supporting the internal coincidence model? J Psychiatr Res 35: 323-329.
    • (2001) J Psychiatr Res , vol.35 , pp. 323-329
    • Benedetti, F.1    Barbini, B.2    Campori, E.3
  • 14
    • 38049035063 scopus 로고    scopus 로고
    • Behavioural sensitization to repeated sleep deprivation in a mice model of mania
    • Benedetti, F., Fresi, F., Maccioni, P., and Smeraldi, E. (2008) Behavioural sensitization to repeated sleep deprivation in a mice model of mania. Behav Brain Res 187: 221-1217.
    • (2008) Behav Brain Res , vol.187 , pp. 221-1217
    • Benedetti, F.1    Fresi, F.2    Maccioni, P.3    Smeraldi, E.4
  • 15
    • 84921189054 scopus 로고
    • The Albert Lasker Medical Awards. Inositol trisphosphate, calcium, lithium, and cell signaling
    • Berridge, M. J. (1989) The Albert Lasker Medical Awards. Inositol trisphosphate, calcium, lithium, and cell signaling. JAMA 262: 1834-1841.
    • (1989) JAMA , vol.262 , pp. 1834-1841
    • Berridge, M.J.1
  • 16
    • 42949133776 scopus 로고    scopus 로고
    • Homozygote inositol transporter knockout mice show a lithium-like phenotype
    • Bersudsky, Y., Shaldubina, A., Agam, G., Berry, G. T., and Belmaker, R. H. (2008) Homozygote inositol transporter knockout mice show a lithium-like phenotype. Bipolar Disord 10: 453-459.
    • (2008) Bipolar Disord , vol.10 , pp. 453-459
    • Bersudsky, Y.1    Shaldubina, A.2    Agam, G.3    Berry, G.T.4    Belmaker, R.H.5
  • 17
    • 77956359560 scopus 로고    scopus 로고
    • Genetic variation in CACNA1C afects brain circuitries related to mental illness
    • Bigos, K. L., Mattay, V. S., Callicott, J. H., et al. (2010) Genetic variation in CACNA1C afects brain circuitries related to mental illness. Arch Gen Psychiatry 67: 939-945.
    • (2010) Arch Gen Psychiatry , vol.67 , pp. 939-945
    • Bigos, K.L.1    Mattay, V.S.2    Callicott, J.H.3
  • 18
    • 78649528989 scopus 로고    scopus 로고
    • Association analysis between polymorphisms in the myo-inositol monophosphatase 2 (IMPA2) gene and bipolar disorder
    • Bloch, P. J., Weller, A. E., Doyle, G. A., et al. (2010) Association analysis between polymorphisms in the myo-inositol monophosphatase 2 (IMPA2) gene and bipolar disorder. Prog Neuropsychopharmacol Biol Psychiatry 34: 1515-1519.
    • (2010) Prog Neuropsychopharmacol Biol Psychiatry , vol.34 , pp. 1515-1519
    • Bloch, P.J.1    Weller, A.E.2    Doyle, G.A.3
  • 19
    • 0033845032 scopus 로고    scopus 로고
    • Mice lacking PKC gamma exhibit decreased anxiety
    • Bowers, B. J., Collins, A. C., Tritto, T., and Wehner, J. M. (2000) Mice lacking PKC gamma exhibit decreased anxiety. Behav Genet 30: 111-121.
    • (2000) Behav Genet , vol.30 , pp. 111-121
    • Bowers, B.J.1    Collins, A.C.2    Tritto, T.3    Wehner, J.M.4
  • 20
    • 70449413778 scopus 로고    scopus 로고
    • Effects of glucocorticoids on mood, memory, and the hippocampus. Treatment and preventive therapy
    • Brown, E. S. (2009) Effects of glucocorticoids on mood, memory, and the hippocampus. Treatment and preventive therapy. Ann NY Acad Sci 1179: 41-55.
    • (2009) Ann NY Acad Sci , vol.1179 , pp. 41-55
    • Brown, E.S.1
  • 21
    • 0012410468 scopus 로고    scopus 로고
    • Mood and cognitive changes during systemic corticosteroid therapy
    • Brown, E. S. and Chandler, P. A. (2001) Mood and cognitive changes during systemic corticosteroid therapy. Prim Care Companion J Clin Psychiatry 3: 17-21.
    • (2001) Prim Care Companion J Clin Psychiatry , vol.3 , pp. 17-21
    • Brown, E.S.1    Chandler, P.A.2
  • 22
    • 0038034210 scopus 로고    scopus 로고
    • Impact of bipolar disorder on a U. S. Community sample
    • Calabrese, J. R., Hirschfeld, R. M., Reed, M., et al. (2003) Impact of bipolar disorder on a U. S. community sample. J Clin Psychiatry 64: 425-432.
    • (2003) J Clin Psychiatry , vol.64 , pp. 425-432
    • Calabrese, J.R.1    Hirschfeld, R.M.2    Reed, M.3
  • 23
    • 33244484360 scopus 로고    scopus 로고
    • Neural circuitry and neuroplasticity in mood disorders: Insights for novel therapeutic targets
    • Carlson, P. J., Singh, J. B., Zarate, C. A., Jr., Drevets, W. C., and Manji, H. K. (2006) Neural circuitry and neuroplasticity in mood disorders: Insights for novel therapeutic targets. NeuroRx 3: 22-41.
    • (2006) Neurorx , vol.3 , pp. 22-41
    • Carlson, P.J.1    Singh, J.B.2    Zarate, C.A.3    Drevets, W.C.4    Manji, H.K.5
  • 24
    • 33748468922 scopus 로고    scopus 로고
    • Examination of behavioral deicits triggered by targeting Bdnf in fetal or postnatal brains of mice
    • Chan, J. P., Unger, T. J., Byrnes, J., and Rios, M. (2006) Examination of behavioral deicits triggered by targeting Bdnf in fetal or postnatal brains of mice. Neuroscience 142: 49-58.
    • (2006) Neuroscience , vol.142 , pp. 49-58
    • Chan, J.P.1    Unger, T.J.2    Byrnes, J.3    Rios, M.4
  • 25
    • 0037806885 scopus 로고    scopus 로고
    • Regulation of cell cycle progression and apoptosis by the Ras/Raf/MEK/ERK pathway (Review)
    • Chang, F., Steelman, L. S., Shelton, J. G., et al. (2003) Regulation of cell cycle progression and apoptosis by the Ras/Raf/MEK/ERK pathway (review). Int J Oncol 22: 469-480.
    • (2003) Int J Oncol , vol.22 , pp. 469-480
    • Chang, F.1    Steelman, L.S.2    Shelton, J.G.3
  • 26
    • 77956442870 scopus 로고    scopus 로고
    • Translational research in bipolar disorder: Emerging insights from genetically based models
    • Chen, G., Henter, I. D., and Manji, H. K. (2010) Translational research in bipolar disorder: Emerging insights from genetically based models. Mol Psychiatry 15: 883-895.
    • (2010) Mol Psychiatry , vol.15 , pp. 883-895
    • Chen, G.1    Henter, I.D.2    Manji, H.K.3
  • 27
    • 33748156957 scopus 로고    scopus 로고
    • The extracellular signal-regulated kinase pathway: An emerging promising target for mood stabilizers
    • Chen, G. and Manji, H. K. (2006) The extracellular signal-regulated kinase pathway: An emerging promising target for mood stabilizers. Curr Opin Psychiatry 19: 313-323.
    • (2006) Curr Opin Psychiatry , vol.19 , pp. 313-323
    • Chen, G.1    Manji, H.K.2
  • 28
    • 0032956630 scopus 로고    scopus 로고
    • Themood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS
    • Chen, G., Zeng, W. Z., Yuan, P. X., et al. (1999) Themood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS. J Neurochem 72: 879-882.
    • (1999) J Neurochem , vol.72 , pp. 879-882
    • Chen, G.1    Zeng, W.Z.2    Yuan, P.X.3
  • 29
    • 44549087727 scopus 로고    scopus 로고
    • Antidepressive-like Effects of rapamycin in animal models: Implications for mTOR inhibition as a new target for treatment of afective disorders
    • Cleary, C., Linde, J. A., Hiscock, K. M., et al. (2008) Antidepressive-like Effects of rapamycin in animal models: Implications for mTOR inhibition as a new target for treatment of afective disorders. Brain Res Bull 76: 469-473.
    • (2008) Brain Res Bull , vol.76 , pp. 469-473
    • Cleary, C.1    Linde, J.A.2    Hiscock, K.M.3
  • 30
    • 34247871294 scopus 로고    scopus 로고
    • Thearmamentarium of treatments for bipolar disorder: A review of the literature
    • Cousins, D. A. and Young, A. H. (2007) Thearmamentarium of treatments for bipolar disorder: A review of the literature. Int J Neuropsychopharmacol 10: 411-431.
    • (2007) Int J Neuropsychopharmacol , vol.10 , pp. 411-431
    • Cousins, D.A.1    Young, A.H.2
  • 32
    • 33947251296 scopus 로고    scopus 로고
    • Lack of lithium-like behavioral and molecular Effects in IMPA2 knockout mice
    • Cryns, K., Shamir, A., Shapiro, J., et al. (2007) Lack of lithium-like behavioral and molecular Effects in IMPA2 knockout mice. Neuropsychopharmacology 32: 881-891.
    • (2007) Neuropsychopharmacology , vol.32 , pp. 881-891
    • Cryns, K.1    Shamir, A.2    Shapiro, J.3
  • 33
    • 38149044120 scopus 로고    scopus 로고
    • IMPA1 is essential for embryonic development and lithium-like pilocarpine sensitivity
    • Cryns, K., Shamir, A., Van Acker, N., et al. (2008) IMPA1 is essential for embryonic development and lithium-like pilocarpine sensitivity. Neuropsychopharmacology 33: 674-684.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 674-684
    • Cryns, K.1    Shamir, A.2    Van Acker, N.3
  • 34
    • 77957900975 scopus 로고    scopus 로고
    • Mood disorder susceptibility gene CACNA1C modiies mood-related behaviors in mice and interacts with sex to inluence behavior in mice and diagnosis in humans
    • Dao, D. T., Mahon, P. B., Cai, X., et al. (2010) Mood disorder susceptibility gene CACNA1C modiies mood-related behaviors in mice and interacts with sex to inluence behavior in mice and diagnosis in humans. Biol Psychiatry 68: 801-810.
    • (2010) Biol Psychiatry , vol.68 , pp. 801-810
    • Dao, D.T.1    Mahon, P.B.2    Cai, X.3
  • 35
    • 77955891255 scopus 로고    scopus 로고
    • A randomized add-on trial of an N-methyl-D-aspartate antagonist in treatment-resistant bipolar depression
    • Diazgranados, N., Ibrahim, L., Brutsche, N. E., et al. (2010) A randomized add-on trial of an N-methyl-D-aspartate antagonist in treatment-resistant bipolar depression. Arch 67: 793-802.
    • (2010) Arch , vol.67 , pp. 793-802
    • Diazgranados, N.1    Ibrahim, L.2    Brutsche, N.E.3
  • 36
    • 0034948210 scopus 로고    scopus 로고
    • Evaluation of nigrostriatal dopaminergic function in adult +/+ and +/-BDNF mutant mice
    • Dluzen, D. E., Gao, X., Story, G. M., et al. (2001) Evaluation of nigrostriatal dopaminergic function in adult +/+ and +/-BDNF mutant mice. Exp Neurol 170: 121-128.
    • (2001) Exp Neurol , vol.170 , pp. 121-128
    • Dluzen, D.E.1    Gao, X.2    Story, G.M.3
  • 37
    • 78649732829 scopus 로고    scopus 로고
    • Lithium ameliorates nucleus accumbens phase-signaling dysfunction in a genetic mouse model of mania
    • Dzirasa, K., Coque, L., Sidor, M. M., et al. (2010) Lithium ameliorates nucleus accumbens phase-signaling dysfunction in a genetic mouse model of mania. J Neurosci 30: 16314-16323.
    • (2010) J Neurosci , vol.30 , pp. 16314-16323
    • Dzirasa, K.1    Coque, L.2    Sidor, M.M.3
  • 38
    • 34548026724 scopus 로고    scopus 로고
    • Diferent behaviors and diferent strains: Potential new ways to model bipolar disorder
    • Einat, H. (2007) Diferent behaviors and diferent strains: Potential new ways to model bipolar disorder. Neurosci Biobehav Rev 31: 850-857.
    • (2007) Neurosci Biobehav Rev , vol.31 , pp. 850-857
    • Einat, H.1
  • 39
    • 84885611921 scopus 로고    scopus 로고
    • Strategies for the development of animal models for bipolar disorder: New opportunities and new challenges
    • C. Zarate and K. H. Manji, Berlin: Springer
    • Einat, H. (2010) Strategies for the development of animal models for bipolar disorder: New opportunities and new challenges. In C. Zarate and K. H. Manji (eds) Behavioral Neurobiology of Bipolar Disorder and its Treatment. Berlin: Springer.
    • (2010) Behavioral Neurobiology of Bipolar Disorder and Its Treatment
    • Einat, H.1
  • 40
    • 0031890731 scopus 로고    scopus 로고
    • Augmentation of lithium’s behavioral efect by inositol uptake inhibitors
    • Einat, H., Kofman, O., Itkin, O., Lewitan, R. J., and Belmaker, R. H. (1998) Augmentation of lithium’s behavioral efect by inositol uptake inhibitors. J Neural Transm 105: 31-38.
    • (1998) J Neural Transm , vol.105 , pp. 31-38
    • Einat, H.1    Kofman, O.2    Itkin, O.3    Lewitan, R.J.4    Belmaker, R.H.5
  • 41
    • 33745468256 scopus 로고    scopus 로고
    • Cellular plasticity cascades: Gene to behavior pathways in animal models of bipolar disorder
    • Einat, H. and Manji, H. K. (2006) Cellular plasticity cascades: Gene to behavior pathways in animal models of bipolar disorder. Biol Psychiatry 59: 1960-1971.
    • (2006) Biol Psychiatry , vol.59 , pp. 1960-1971
    • Einat, H.1    Manji, H.K.2
  • 42
    • 0344011031 scopus 로고    scopus 로고
    • Possible involvement of the ERK signaling cascade in bipolar disorder: Behavioral leads from the study of mutant mice
    • Einat, H., Manji, H. K., Gould, T. D., Du, J., and Chen, G. (2003a) Possible involvement of the ERK signaling cascade in bipolar disorder: Behavioral leads from the study of mutant mice. Drug News Perspect 16: 453-563.
    • (2003) Drug News Perspect , vol.16 , pp. 453-563
    • Einat, H.1    Manji, H.K.2    Gould, T.D.3    Du, J.4    Chen, G.5
  • 43
    • 84953254459 scopus 로고    scopus 로고
    • Prospects for the development of animal models for the study of bipolar disorder
    • J. C. Soares and A. Young, 2nd edn. New York: Taylor & Francis
    • Einat, H., Shaldubina, A., Bersudskey, Y., and Belmaker, R. H. (2007a) Prospects for the development of animal models for the study of bipolar disorder. In J. C. Soares and A. Young (eds) Bipolar Disorder: Basic Mechanisms and herapeutic Implications, 2nd edn. New York: Taylor & Francis.
    • (2007) Bipolar Disorder: Basic Mechanisms and Herapeutic Implications
    • Einat, H.1    Shaldubina, A.2    Bersudskey, Y.3    Belmaker, R.H.4
  • 44
    • 0043240266 scopus 로고    scopus 로고
    • Therole of the extracellular signal-regulated kinase signaling pathway in mood modulation
    • Einat, H., Yuan, P., Gould, T. D., et al. (2003b) Therole of the extracellular signal-regulated kinase signaling pathway in mood modulation. J Neurosci 23: 7311-7316.
    • (2003) J Neurosci , vol.23 , pp. 7311-7316
    • Einat, H.1    Yuan, P.2    Gould, T.D.3
  • 45
    • 27644511756 scopus 로고    scopus 로고
    • Increased anxiety-like behaviors and mitochondrial dysfunction in mice with targeted mutation of the Bcl-2 gene: Further support for the involvement of mitochondrial function in anxiety disorders
    • Einat, H., Yuan, P., and Manji, H. K. (2005) Increased anxiety-like behaviors and mitochondrial dysfunction in mice with targeted mutation of the Bcl-2 gene: Further support for the involvement of mitochondrial function in anxiety disorders. Behav Brain Res 165: 172-180.
    • (2005) Behav Brain Res , vol.165 , pp. 172-180
    • Einat, H.1    Yuan, P.2    Manji, H.K.3
  • 46
    • 34548433808 scopus 로고    scopus 로고
    • Protein kinase C inhibition by tamoxifen antagonizes manic-like behavior in rats: Implications for the development of novel therapeutics for bipolar disorder
    • Einat, H., Yuan, P., Szabo, S. T., Dogra, S., and Manji, H. K. (2007b) Protein kinase C inhibition by tamoxifen antagonizes manic-like behavior in rats: Implications for the development of novel therapeutics for bipolar disorder. Neuropsychobiology 55: 123-131.
    • (2007) Neuropsychobiology , vol.55 , pp. 123-131
    • Einat, H.1    Yuan, P.2    Szabo, S.T.3    Dogra, S.4    Manji, H.K.5
  • 47
    • 0000683636 scopus 로고
    • Animal models with construct validity for schizophrenia
    • Ellenbroek, B. A. and Cools, A. R. (1990) Animal models with construct validity for schizophrenia. Behav Pharmacol 1: 469-490.
    • (1990) Behav Pharmacol , vol.1 , pp. 469-490
    • Ellenbroek, B.A.1    Cools, A.R.2
  • 48
    • 62849084624 scopus 로고    scopus 로고
    • Theextracellular signal-regulated kinase pathway contributes to the control of behavioral excitement
    • Engel, S. R., Creson, T. K., Hao, Y., et al. (2009) Theextracellular signal-regulated kinase pathway contributes to the control of behavioral excitement. Mol Psychiatry 14: 448-461.
    • (2009) Mol Psychiatry , vol.14 , pp. 448-461
    • Engel, S.R.1    Creson, T.K.2    Hao, Y.3
  • 49
    • 77957762046 scopus 로고    scopus 로고
    • Does gene deletion of AMPA GluA1 phenocopy features of schizoafective disorder?
    • Fitzgerald, P. J., Barkus, C., Feyder, M., et al. (2010) Does gene deletion of AMPA GluA1 phenocopy features of schizoafective disorder? Neurobiol Dis 40: 608-621.
    • (2010) Neurobiol Dis , vol.40 , pp. 608-621
    • Fitzgerald, P.J.1    Barkus, C.2    Feyder, M.3
  • 50
    • 77957789673 scopus 로고    scopus 로고
    • Strain-specific battery of tests for domains of mania: Effects of valproate, lithium and imipramine
    • Flaisher-Grinberg, S. and Einat, H. (2010) Strain-specific battery of tests for domains of mania: Effects of valproate, lithium and imipramine. Front Psychopharmacology 1: 1-10.
    • (2010) Front Psychopharmacology , vol.1 , pp. 1-10
    • Flaisher-Grinberg, S.1    Einat, H.2
  • 51
    • 77953050858 scopus 로고    scopus 로고
    • Models of mania: From facets to domains and from animal models to model animals
    • Flaisher-Grinberg, S., Kronfeld-Schor, N., and Einat, H. (2010) Models of mania: From facets to domains and from animal models to model animals. J Psychopharmacology 24: 437-438.
    • (2010) J Psychopharmacology , vol.24 , pp. 437-438
    • Flaisher-Grinberg, S.1    Kronfeld-Schor, N.2    Einat, H.3
  • 52
    • 0027278902 scopus 로고
    • Altered platelet protein kinase C activity in bipolar afective disorder, manic episode
    • Friedman, E., Hoau Yan, W., Levinson, D., Connell, T. A., and Singh, H. (1993) Altered platelet protein kinase C activity in bipolar afective disorder, manic episode. Biol Psychiatry 33: 520-525.
    • (1993) Biol Psychiatry , vol.33 , pp. 520-525
    • Friedman, E.1    Hoau Yan, W.2    Levinson, D.3    Connell, T.A.4    Singh, H.5
  • 53
    • 84856643478 scopus 로고    scopus 로고
    • Loss of deacetylation activity of Hdac6 afects emotional behavior in mice
    • Fukada, M., Hanai, A., Nakayama, A., et al. (2012) Loss of deacetylation activity of Hdac6 afects emotional behavior in mice. PLoS One 7: E30924.
    • (2012) Plos One , vol.7
    • Fukada, M.1    Hanai, A.2    Nakayama, A.3
  • 55
    • 0034917841 scopus 로고    scopus 로고
    • Pharmacological studies of prepulse inhibition models of sensorimotor gating deicits in schizophrenia: A decade in review
    • Geyer, M. A., Krebs-homson, K., Braf, D. L., and Swerdlow, N. R. (2001) Pharmacological studies of prepulse inhibition models of sensorimotor gating deicits in schizophrenia: A decade in review. Psychopharmacology 156: 117-154.
    • (2001) Psychopharmacology , vol.156 , pp. 117-154
    • Geyer, M.A.1    Krebs-Homson, K.2    Braf, D.L.3    Swerdlow, N.R.4
  • 57
    • 34548040641 scopus 로고    scopus 로고
    • Animal models of bipolar disorder and mood stabilizer efficacy: A critical need for improvement
    • Gould, T. D. and Einat, H. (2007) Animal models of bipolar disorder and mood stabilizer efficacy: A critical need for improvement. Neurosci Biobehav Rev 31: 825-831.
    • (2007) Neurosci Biobehav Rev , vol.31 , pp. 825-831
    • Gould, T.D.1    Einat, H.2
  • 58
    • 10644255687 scopus 로고    scopus 로고
    • AR-A014418, a selective GSK-3 inhibitor, produces antidepressant-like Effects in the forced swim test
    • Gould, T. D., Einat, H., Bhat, R., and Manji, H. K. (2004) AR-A014418, a selective GSK-3 inhibitor, produces antidepressant-like Effects in the forced swim test. Int J Neuropsychopharmacol 7: 387-390.
    • (2004) Int J Neuropsychopharmacol , vol.7 , pp. 387-390
    • Gould, T.D.1    Einat, H.2    Bhat, R.3    Manji, H.K.4
  • 59
    • 34548684164 scopus 로고    scopus 로고
    • Beta-catenin overexpression in the mouse brain phenocopies lithium-sensitive behaviors
    • Gould, T. D., Einat, H., O’Donnell, K. C., et al. (2007a) Beta-catenin overexpression in the mouse brain phenocopies lithium-sensitive behaviors. Neuropsychopharmacology 32: 2173-2183.
    • (2007) Neuropsychopharmacology , vol.32 , pp. 2173-2183
    • Gould, T.D.1    Einat, H.2    O’Donnell, K.C.3
  • 60
    • 33644753148 scopus 로고    scopus 로고
    • Psychiatric endophenotypes and the development of valid animal models
    • Gould, T. D. and Gottesman, I. I. (2006) Psychiatric endophenotypes and the development of valid animal models. Genes Brain Behav 5: 113-119.
    • (2006) Genes Brain Behav , vol.5 , pp. 113-119
    • Gould, T.D.1    Gottesman, I.I.2
  • 61
    • 2942750240 scopus 로고    scopus 로고
    • Themolecular medicine revolution and psychiatry: Bridging the gap between basic neuroscience research and clinical psychiatry
    • Gould, T. D. and Manji, H. K. (2004) Themolecular medicine revolution and psychiatry: Bridging the gap between basic neuroscience research and clinical psychiatry. J Clin Psychiatry 65: 598-604.
    • (2004) J Clin Psychiatry , vol.65 , pp. 598-604
    • Gould, T.D.1    Manji, H.K.2
  • 62
    • 34249087808 scopus 로고    scopus 로고
    • Strain diferences in lithium attenuation of d-amphetamine-induced hyperlocomotion: A mouse model for the genetics of clinical response to lithium
    • Gould, T. D., O’Donnell, K. C., Picchini, A. M., and Manji, H. K. (2007b) Strain diferences in lithium attenuation of d-amphetamine-induced hyperlocomotion: A mouse model for the genetics of clinical response to lithium. Neuropsychopharmacology 32: 1321-1333.
    • (2007) Neuropsychopharmacology , vol.32 , pp. 1321-1333
    • Gould, T.D.1    O’Donnell, K.C.2    Picchini, A.M.3    Manji, H.K.4
  • 63
    • 40849094032 scopus 로고    scopus 로고
    • Generation and behavioral characterization of [beta]-catenin forebrain-specific conditional knock-out mice
    • Gould, T. D., O’Donnell, K. C., Picchini, A. M., et al. (2008) Generation and behavioral characterization of [beta]-catenin forebrain-specific conditional knock-out mice. Behav Brain Res 189: 117.
    • (2008) Behav Brain Res , vol.189 , pp. 117
    • Gould, T.D.1    O’Donnell, K.C.2    Picchini, A.M.3
  • 64
    • 33745466932 scopus 로고    scopus 로고
    • Targeting glycogen synthase kinase-3 in the CNS: Implications for the development of new treatments for mood disorders
    • Gould, T. D., Picchini, A. M., Einat, H., and Manji, H. K. (2006) Targeting glycogen synthase kinase-3 in the CNS: Implications for the development of new treatments for mood disorders. Curr Drug Targets 7: 1399-1409.
    • (2006) Curr Drug Targets , vol.7 , pp. 1399-1409
    • Gould, T.D.1    Picchini, A.M.2    Einat, H.3    Manji, H.K.4
  • 65
    • 0029091740 scopus 로고
    • Role of BCL-2 in the survival and function of developing and mature sympathetic neurons
    • Greenlund, L. J., Korsmeyer, S. J., and Johnson E. M., Jr. (1995) Role of BCL-2 in the survival and function of developing and mature sympathetic neurons. Neuron 15: 649-661.
    • (1995) Neuron , vol.15 , pp. 649-661
    • Greenlund, L.J.1    Korsmeyer, S.J.2    Johnson, E.M.3
  • 66
    • 0029658372 scopus 로고    scopus 로고
    • Localization of Bax and Bcl-2 proteins, regulators of programmed cell death, in the human central nervous system
    • Hara, A., Hirose, Y., Wang, A., et al. (1996) Localization of Bax and Bcl-2 proteins, regulators of programmed cell death, in the human central nervous system. Virchows Arch 429: 249-253.
    • (1996) Virchows Arch , vol.429 , pp. 249-253
    • Hara, A.1    Hirose, Y.2    Wang, A.3
  • 67
    • 46749110735 scopus 로고    scopus 로고
    • Sleep and circadian rhythms in bipolar disorder: Seeking synchrony, harmony, and regulation
    • Harvey, A. G. (2008) Sleep and circadian rhythms in bipolar disorder: Seeking synchrony, harmony, and regulation. Am J Psychiatry 165: 820-829.
    • (2008) Am J Psychiatry , vol.165 , pp. 820-829
    • Harvey, A.G.1
  • 68
    • 33749614540 scopus 로고    scopus 로고
    • Effects of genetically altered brain glucocorticoid receptor action on behavior and adrenal axis regulation in mice
    • Howell, M. P. and Muglia, L. J. (2006) Effects of genetically altered brain glucocorticoid receptor action on behavior and adrenal axis regulation in mice. Front Neuroendocrinol 27: 275-284.
    • (2006) Front Neuroendocrinol , vol.27 , pp. 275-284
    • Howell, M.P.1    Muglia, L.J.2
  • 69
    • 0034927081 scopus 로고    scopus 로고
    • Neurotrophins: Roles in neuronal development and function
    • Huang, E. J. and Reichardt, L. F. (2001) Neurotrophins: Roles in neuronal development and function. Ann Rev Neurosci 24: 677-736.
    • (2001) Ann Rev Neurosci , vol.24 , pp. 677-736
    • Huang, E.J.1    Reichardt, L.F.2
  • 70
    • 34249107980 scopus 로고    scopus 로고
    • Desipramine activated Bcl-2 expression and inhibited lipopolysaccharide-induced apoptosis in hippocampus-derived adult neural stem cells
    • Huang, Y. Y., Peng, C. H., Yang, Y. P., et al. (2007) Desipramine activated Bcl-2 expression and inhibited lipopolysaccharide-induced apoptosis in hippocampus-derived adult neural stem cells. J Pharmacol Sci 104: 61-72.
    • (2007) J Pharmacol Sci , vol.104 , pp. 61-72
    • Huang, Y.Y.1    Peng, C.H.2    Yang, Y.P.3
  • 71
    • 36549042579 scopus 로고    scopus 로고
    • From animal models to model animals
    • Insel, T. R. (2007) From animal models to model animals. Biol Psychiatry 62: 1337-1339.
    • (2007) Biol Psychiatry , vol.62 , pp. 1337-1339
    • Insel, T.R.1
  • 72
    • 33750978676 scopus 로고    scopus 로고
    • Noradrenaline is necessary for the hedonic properties of addictive drugs
    • Jasmin, L., Narasaiah, M., and Tien, D. (2006) Noradrenaline is necessary for the hedonic properties of addictive drugs. Vascul Pharmacol 45: 243-250.
    • (2006) Vascul Pharmacol , vol.45 , pp. 243-250
    • Jasmin, L.1    Narasaiah, M.2    Tien, D.3
  • 73
    • 1842420631 scopus 로고    scopus 로고
    • Rapid antidepressive-like activity of specific glycogen synthase kinase-3 inhibitor and its efect on beta-catenin in mouse hippocampus
    • Kaidanovich-Beilin, O., Milman, A., Weizman, A., Pick, C. G., and Eldar-Finkelman, H. (2004) Rapid antidepressive-like activity of specific glycogen synthase kinase-3 inhibitor and its efect on beta-catenin in mouse hippocampus. Biol Psychiatry 55: 781-784.
    • (2004) Biol Psychiatry , vol.55 , pp. 781-784
    • Kaidanovich-Beilin, O.1    Milman, A.2    Weizman, A.3    Pick, C.G.4    Eldar-Finkelman, H.5
  • 74
    • 78149448880 scopus 로고    scopus 로고
    • Diacylglycerol kinase beta knockout mice exhibit lithium-sensitive behavioral abnormalities
    • Kakefuda, K., Oyagi, A., Ishisaka, M., et al. (2010) Diacylglycerol kinase beta knockout mice exhibit lithium-sensitive behavioral abnormalities. PLoS One 5: E13447.
    • (2010) Plos One , vol.5
    • Kakefuda, K.1    Oyagi, A.2    Ishisaka, M.3
  • 75
    • 80052961098 scopus 로고    scopus 로고
    • Evidence for antimanic eicacy of glycogen synthase kinase-3 (GSK-3) inhibitors in a strain specific model of acute mania
    • Kalinichev, M. and Dawson, L. A. (2011) Evidence for antimanic eicacy of glycogen synthase kinase-3 (GSK-3) inhibitors in a strain specific model of acute mania. Int J Neuropsychopharmacol 6: 1-17.
    • (2011) Int J Neuropsychopharmacol , vol.6 , pp. 1-17
    • Kalinichev, M.1    Dawson, L.A.2
  • 76
    • 0030605403 scopus 로고    scopus 로고
    • Theregulation of AP-1 activity by mitogen-activated protein kinases
    • Karin, M. (1996) Theregulation of AP-1 activity by mitogen-activated protein kinases. Philos Trans R Soc Lond B Biol Sci 351: 127-134.
    • (1996) Philos Trans R Soc Lond B Biol Sci , vol.351 , pp. 127-134
    • Karin, M.1
  • 77
    • 33745712834 scopus 로고    scopus 로고
    • Mice with neuron-specific accumulation of mitochondrial DNA mutations show mood disorder-like phenotypes
    • Kasahara, T., Kubota, M., Miyauchi, T., et al. (2006) Mice with neuron-specific accumulation of mitochondrial DNA mutations show mood disorder-like phenotypes. Mol Psychiatry 11: 577-593.
    • (2006) Mol Psychiatry , vol.11 , pp. 577-593
    • Kasahara, T.1    Kubota, M.2    Miyauchi, T.3
  • 78
    • 0034653422 scopus 로고    scopus 로고
    • BDNF regulates eating behavior and locomotor activity in mice
    • Kernie, S. G., Liebl, D. J., and Parada, L. F. (2000) BDNF regulates eating behavior and locomotor activity in mice. EMBO J 19: 1290-1300.
    • (2000) EMBO J , vol.19 , pp. 1290-1300
    • Kernie, S.G.1    Liebl, D.J.2    Parada, L.F.3
  • 79
    • 0029776032 scopus 로고    scopus 로고
    • A molecular mechanism for the efect of lithium on development
    • Klein, P. S. and Melton, D. A. (1996) A molecular mechanism for the efect of lithium on development. Proc Natl Acad Sci USA 93: 8455-8459.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 8455-8459
    • Klein, P.S.1    Melton, D.A.2
  • 80
    • 0026049336 scopus 로고
    • Myo-inositol attenuates two specific behavioral Effects of acute lithium in rats
    • Kofman, O., Belmaker, R. H., Grisaru, N., et al. (1991) Myo-inositol attenuates two specific behavioral Effects of acute lithium in rats. Psychopharmacol Bull 27: 185-190.
    • (1991) Psychopharmacol Bull , vol.27 , pp. 185-190
    • Kofman, O.1    Belmaker, R.H.2    Grisaru, N.3
  • 82
    • 80054096382 scopus 로고    scopus 로고
    • Circadian rhythms and depression: Human psychopathology and animal models
    • Kronfeld-Schor, N. and Einat, H. (2012) Circadian rhythms and depression: Human psychopathology and animal models. Neuropharmacology 62: 101-114.
    • (2012) Neuropharmacology , vol.62 , pp. 101-114
    • Kronfeld-Schor, N.1    Einat, H.2
  • 83
    • 18944369872 scopus 로고    scopus 로고
    • Theincreasing medical burden in bipolar disorder
    • Kupfer, D. J. (2005) Theincreasing medical burden in bipolar disorder. JAMA 293: 2528-2530.
    • (2005) JAMA , vol.293 , pp. 2528-2530
    • Kupfer, D.J.1
  • 84
    • 79952190583 scopus 로고    scopus 로고
    • Developing therapeutics for bipolar disorder: From animal models to the clinic
    • R. A. McArthur and F. Borsini (eds), Amsterdam: Elsevier
    • Large, C. H., Einat, H., and Mahableshwarkar, A. R. (2008) Developing therapeutics for bipolar disorder: From animal models to the clinic. In R. A. McArthur and F. Borsini (eds) Animal and Translational Models for CNS Drug Discovery. Amsterdam: Elsevier.
    • (2008) Animal and Translational Models for CNS Drug Discovery
    • Large, C.H.1    Einat, H.2    Mahableshwarkar, A.R.3
  • 85
    • 40449122600 scopus 로고    scopus 로고
    • Phenomic, convergent functional genomic, and biomarker studies in a stress-reactive genetic animal model of bipolar disorder and co-morbid alcoholism
    • Le-Niculescu, H., McFarland, M. J., Ogden, C. A., et al. (2008) Phenomic, convergent functional genomic, and biomarker studies in a stress-reactive genetic animal model of bipolar disorder and co-morbid alcoholism. Am J Med Genet B Neuropsychiatr Genet 147B: 134-166.
    • (2008) Am J Med Genet B Neuropsychiatr Genet , vol.147B , pp. 134-166
    • Le-Niculescu, H.1    McFarland, M.J.2    Ogden, C.A.3
  • 86
    • 84862880328 scopus 로고    scopus 로고
    • TheALDH2 and 5-HT2A genes interacted in bipolar-I but not bipolar-II disorder
    • Lee, S. Y., Chen, S. L., Chang, Y. H., et al. (2012) TheALDH2 and 5-HT2A genes interacted in bipolar-I but not bipolar-II disorder. Prog Neuropsychopharmacol Biol Psychiatry 38: 247-251.
    • (2012) Prog Neuropsychopharmacol Biol Psychiatry , vol.38 , pp. 247-251
    • Lee, S.Y.1    Chen, S.L.2    Chang, Y.H.3
  • 87
    • 78049495832 scopus 로고    scopus 로고
    • Regulation of glycogen synthase kinase-3 during bipolar mania treatment
    • Li, X., Liu, M., Cai, Z., andWang, G. (2010) Regulation of glycogen synthase kinase-3 during bipolar mania treatment. Bipolar Disord 12: 741-752.
    • (2010) Bipolar Disord , vol.12 , pp. 741-752
    • Li, X.1    Liu, M.2    Cai, Z.3    Wang, G.4
  • 88
    • 52049108075 scopus 로고    scopus 로고
    • Behavioral Effects of Bcl-2 deiciency: Implications for afective disorders
    • Lien, R., Flaisher-Grinberg, S., Cleary, C., Hejny, M., and Einat, H. (2008) Behavioral Effects of Bcl-2 deiciency: Implications for afective disorders. Pharmacol Rep 60: 490-498.
    • (2008) Pharmacol Rep , vol.60 , pp. 490-498
    • Lien, R.1    Flaisher-Grinberg, S.2    Cleary, C.3    Hejny, M.4    Einat, H.5
  • 89
    • 79959954934 scopus 로고    scopus 로고
    • The MEK inhibitor SL327 blocks acquisition but not expression of lithium-induced conditioned place aversion: A behavioral and immunohistochemical study
    • Longoni, R., Spina, L., Vinci, S., and Acquas, E. (2011) The MEK inhibitor SL327 blocks acquisition but not expression of lithium-induced conditioned place aversion: A behavioral and immunohistochemical study. Psychopharmacology 216: 63-73.
    • (2011) Psychopharmacology , vol.216 , pp. 63-73
    • Longoni, R.1    Spina, L.2    Vinci, S.3    Acquas, E.4
  • 90
    • 0035017384 scopus 로고    scopus 로고
    • Sensitivity to the Effects of pharmacologically selective antidepressants in diferent strains of mice
    • Lucki, I., Dalvi, A., and Mayorga, A. J. (2001) Sensitivity to the Effects of pharmacologically selective antidepressants in diferent strains of mice. Psychopharmacology 155: 315-322.
    • (2001) Psychopharmacology , vol.155 , pp. 315-322
    • Lucki, I.1    Dalvi, A.2    Mayorga, A.J.3
  • 91
    • 5344262388 scopus 로고    scopus 로고
    • Post-stress changes in BDNF and Bcl-2 immunoreactivities in hippocampal neurons: Effect of chronic administration of olanzapine
    • Luo, C., Xu, H., and Li, X. M. (2004) Post-stress changes in BDNF and Bcl-2 immunoreactivities in hippocampal neurons: Effect of chronic administration of olanzapine. Brain Res 1025: 194-202.
    • (2004) Brain Res , vol.1025 , pp. 194-202
    • Luo, C.1    Xu, H.2    Li, X.M.3
  • 93
    • 0033592920 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor-deicient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities
    • Lyons, W. E., Mamounas, L. A., Ricaurte, G. A., et al. (1999) Brain-derived neurotrophic factor-deicient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities. Proc Natl Acad Sci USA 96: 15239-15244.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 15239-15244
    • Lyons, W.E.1    Mamounas, L.A.2    Ricaurte, G.A.3
  • 94
    • 84855545792 scopus 로고    scopus 로고
    • Novel glutamatergic agents for major depressive disorder and bipolar disorder
    • Machado-Vieira, R., Ibrahim, L., Henter, I. D., and Zarate, C. A., Jr. (2012) Novel glutamatergic agents for major depressive disorder and bipolar disorder. Pharmacol Biochem Behav 100: 678-687.
    • (2012) Pharmacol Biochem Behav , vol.100 , pp. 678-687
    • Machado-Vieira, R.1    Ibrahim, L.2    Henter, I.D.3    Zarate, C.A.4
  • 96
    • 47249165549 scopus 로고    scopus 로고
    • BAG1 plays a critical role in regulating recovery from both manic-like and depression-like behavioral impairments
    • Maeng, S., Hunsberger, J. G., Pearson, B., et al. (2008) BAG1 plays a critical role in regulating recovery from both manic-like and depression-like behavioral impairments. Proc Natl Acad Sci USA 105: 8766-8771.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 8766-8771
    • Maeng, S.1    Hunsberger, J.G.2    Pearson, B.3
  • 97
    • 67650311660 scopus 로고    scopus 로고
    • Reverse translational strategies for developing animal models of bipolar disorder
    • Malkesman, O., Austin, D. R., Chen, G., and Manji, H. K. (2009a) Reverse translational strategies for developing animal models of bipolar disorder. Dis Model Mech 2: 238-245.
    • (2009) Dis Model Mech , vol.2 , pp. 238-245
    • Malkesman, O.1    Austin, D.R.2    Chen, G.3    Manji, H.K.4
  • 98
    • 77950369626 scopus 로고    scopus 로고
    • The female urine sniing test: A novel approach for assessing reward-seeking behavior in rodents
    • Malkesman, O., Scattoni, M. L., Paredes, D., et al. (2009b) The female urine sniing test: A novel approach for assessing reward-seeking behavior in rodents. Biol Psychiatry 67: 864-871.
    • (2009) Biol Psychiatry , vol.67 , pp. 864-871
    • Malkesman, O.1    Scattoni, M.L.2    Paredes, D.3
  • 99
    • 0035295487 scopus 로고    scopus 로고
    • Impairments of neuroplasticity and cellular resilience in severe mood disorders: Implications for the development of novel therapeutics
    • Manji, H. K. and Duman, R. S. (2001) Impairments of neuroplasticity and cellular resilience in severe mood disorders: Implications for the development of novel therapeutics. Psychopharmacol Bull 35: 5-49.
    • (2001) Psychopharmacol Bull , vol.35 , pp. 5-49
    • Manji, H.K.1    Duman, R.S.2
  • 100
    • 0009789399 scopus 로고    scopus 로고
    • Lithium up-regulates the cytoprotective protein Bcl-2 in the CNS in vivo: A role for neurotrophic and neuroprotective Effects in manic depressive illness
    • Manji, H. K., Moore, G. J., and Chen, G. (2000) Lithium up-regulates the cytoprotective protein Bcl-2 in the CNS in vivo: A role for neurotrophic and neuroprotective Effects in manic depressive illness. J Clin Psychiatry 61: 82-96.
    • (2000) J Clin Psychiatry , vol.61 , pp. 82-96
    • Manji, H.K.1    Moore, G.J.2    Chen, G.3
  • 102
    • 77951798728 scopus 로고    scopus 로고
    • Pharmacology and eicacy of asenapine for manic and mixed states in adults with bipolar disorder
    • McIntyre, R. S. (2010) Pharmacology and eicacy of asenapine for manic and mixed states in adults with bipolar disorder. Expert Rev Neurother 10: 645-649.
    • (2010) Expert Rev Neurother , vol.10 , pp. 645-649
    • McIntyre, R.S.1
  • 103
    • 66249086541 scopus 로고    scopus 로고
    • The role of hypothalamic pituitary-adrenal axis dysfunction in the etiology of depressive disorders
    • McIsaac, S. A. and Young, A. H. (2009) The role of hypothalamic pituitary-adrenal axis dysfunction in the etiology of depressive disorders. Drugs Today 45: 127-133.
    • (2009) Drugs Today , vol.45 , pp. 127-133
    • McIsaac, S.A.1    Young, A.H.2
  • 104
    • 0014560655 scopus 로고
    • Animal model of depression. I. Review of evidence: Implications for research
    • McKinney, W. T., Jr. and Bunney, W. E., Jr. (1969) Animal model of depression. I. Review of evidence: Implications for research. Arch Gen Psychiatry 21: 240-248.
    • (1969) Arch Gen Psychiatry , vol.21 , pp. 240-248
    • McKinney, W.T.1    Bunney, W.E.2
  • 105
    • 0020573592 scopus 로고
    • Effect of lithium carbonate on serotonin uptake in blood platelets of patients with affective disorders
    • Meltzer, H. Y., Arora, R. C., and Goodnick, P. (1983) Effect of lithium carbonate on serotonin uptake in blood platelets of patients with affective disorders. J Afect Disord 5: 215-221.
    • (1983) J Afect Disord , vol.5 , pp. 215-221
    • Meltzer, H.Y.1    Arora, R.C.2    Goodnick, P.3
  • 106
    • 0015521655 scopus 로고
    • Biogenic amine metabolites in cerebrospinal fluid of depressed and manic patients
    • Mendels, J., Frazer, A., Fitzgerald, R. G., Ramsey, T. A., and Stokes, J. W. (1972) Biogenic amine metabolites in cerebrospinal fluid of depressed and manic patients. Science 175: 1380-1382.
    • (1972) Science , vol.175 , pp. 1380-1382
    • Mendels, J.1    Frazer, A.2    Fitzgerald, R.G.3    Ramsey, T.A.4    Stokes, J.W.5
  • 107
    • 34247536530 scopus 로고    scopus 로고
    • Lifetime and 12-month prevalence of bipolar spectrum disorder in the National Comorbidity Survey replication
    • Merikangas, K. R., Akiskal, H. S., Angst, J., et al. (2007) Lifetime and 12-month prevalence of bipolar spectrum disorder in the National Comorbidity Survey replication. Arch Gen Psychiatry 64: 543-552.
    • (2007) Arch Gen Psychiatry , vol.64 , pp. 543-552
    • Merikangas, K.R.1    Akiskal, H.S.2    Angst, J.3
  • 108
    • 0035819481 scopus 로고    scopus 로고
    • Burden of disease-implications for future research
    • Michaud, C. M., Murray, C. J., and Bloom, B. R. (2001) Burden of disease-implications for future research. JAMA 285: 535-539.
    • (2001) JAMA , vol.285 , pp. 535-539
    • Michaud, C.M.1    Murray, C.J.2    Bloom, B.R.3
  • 109
    • 81255134846 scopus 로고    scopus 로고
    • Following the genes: A framework for animal modeling of psychiatric disorders
    • Mitchell, K. J., Huang, Z. J., Moghaddam, B., and Sawa, A. (2011) Following the genes: A framework for animal modeling of psychiatric disorders. BMC Biol 9: 76.
    • (2011) BMC Biol , vol.9 , pp. 76
    • Mitchell, K.J.1    Huang, Z.J.2    Moghaddam, B.3    Sawa, A.4
  • 110
    • 11844288311 scopus 로고    scopus 로고
    • Animal models of depressive illness: The importance of chronic drug treatment
    • Mitchell, P. J. and Redfern, P. H. (2005) Animal models of depressive illness: The importance of chronic drug treatment. Curr Pharm Des 11: 171-203.
    • (2005) Curr Pharm Des , vol.11 , pp. 171-203
    • Mitchell, P.J.1    Redfern, P.H.2
  • 111
    • 0029421811 scopus 로고
    • Experimental models and behavioural tests used in the study of Parkinson’s disease
    • Mokry, J. (1995) Experimental models and behavioural tests used in the study of Parkinson’s disease. Physiol Res 44: 143-150.
    • (1995) Physiol Res , vol.44 , pp. 143-150
    • Mokry, J.1
  • 112
    • 0141542646 scopus 로고    scopus 로고
    • Limbic corticotropinreleasing hormone receptor 1 mediates anxiety-related behavior and hormonal adaptation to stress
    • Muller, M. B., Zimmermann, S., Sillaber, I., et al. (2003) Limbic corticotropinreleasing hormone receptor 1 mediates anxiety-related behavior and hormonal adaptation to stress. Nat Neurosci 6: 1100-1107.
    • (2003) Nat Neurosci , vol.6 , pp. 1100-1107
    • Muller, M.B.1    Zimmermann, S.2    Sillaber, I.3
  • 113
    • 0014597267 scopus 로고
    • Stimulation by lithium of monoamine uptake in human platelets
    • Murphy, D. L., Colburn, R. W., Davis, J. M., and Bunney, W. E., Jr. (1969) Stimulation by lithium of monoamine uptake in human platelets. Life Sci 8: 1187-1193.
    • (1969) Life Sci , vol.8 , pp. 1187-1193
    • Murphy, D.L.1    Colburn, R.W.2    Davis, J.M.3    Bunney, W.E.4
  • 114
    • 0037106975 scopus 로고    scopus 로고
    • Preclinical models: Status of basic research in depression
    • Nestler, E. J., Gould, E., Manji, H., et al. (2002) Preclinical models: Status of basic research in depression. Biol Psychiatry 52: 503-528.
    • (2002) Biol Psychiatry , vol.52 , pp. 503-528
    • Nestler, E.J.1    Gould, E.2    Manji, H.3
  • 115
    • 77957273984 scopus 로고    scopus 로고
    • Animal models of neuropsychiatric disorders
    • Nestler, E. J. and Hyman, S. E. (2010) Animal models of neuropsychiatric disorders. Nat Neurosci 13: 1161-1169.
    • (2010) Nat Neurosci , vol.13 , pp. 1161-1169
    • Nestler, E.J.1    Hyman, S.E.2
  • 116
    • 59449104331 scopus 로고    scopus 로고
    • Neurobiological evidence for thalamic, hippocampal and related glutamatergic abnormalities in bipolar disorder: A review and synthesis
    • Ng, W. X., Lau, I. Y., Graham, S., and Sim, K. (2009) Neurobiological evidence for thalamic, hippocampal and related glutamatergic abnormalities in bipolar disorder: A review and synthesis. Neurosci Biobehav Rev 33: 336-354.
    • (2009) Neurosci Biobehav Rev , vol.33 , pp. 336-354
    • Ng, W.X.1    Lau, I.Y.2    Graham, S.3    Sim, K.4
  • 117
    • 15744364197 scopus 로고    scopus 로고
    • Examination of the clock gene Cryptochrome 1 in bipolar disorder: Mutational analysis and absence of evidence for linkage or association
    • Nievergelt, C. M., Kripke, D. F., Remick, R. A., et al. (2005) Examination of the clock gene Cryptochrome 1 in bipolar disorder: Mutational analysis and absence of evidence for linkage or association. Psychiatr Genet 15: 45-52.
    • (2005) Psychiatr Genet , vol.15 , pp. 45-52
    • Nievergelt, C.M.1    Kripke, D.F.2    Remick, R.A.3
  • 118
    • 3342955475 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 beta haploinsuiciency mimics the behavioral and molecular Effects of lithium
    • O’Brien, W. T., Harper, A. D., Jove, F., et al. (2004) Glycogen synthase kinase-3 beta haploinsuiciency mimics the behavioral and molecular Effects of lithium. J Neurosci 24: 6791-6798.
    • (2004) J Neurosci , vol.24 , pp. 6791-6798
    • O’Brien, W.T.1    Harper, A.D.2    Jove, F.3
  • 119
    • 84856443362 scopus 로고    scopus 로고
    • Genetic approaches to a better understanding of bipolar disorder
    • Oford, J. (2012) Genetic approaches to a better understanding of bipolar disorder. Pharmacolher 133: 133-141.
    • (2012) Pharmacolher , vol.133 , pp. 133-141
    • Oford, J.1
  • 120
    • 77952885202 scopus 로고    scopus 로고
    • Behavioral analyses of transgenic mice harboring bipolar disorder candidate genes, IMPA1 and IMPA2
    • Ohnishi, T., Watanabe, A., Ohba, H., et al. (2010) Behavioral analyses of transgenic mice harboring bipolar disorder candidate genes, IMPA1 and IMPA2. Neurosci Res 67: 86-94.
    • (2010) Neurosci Res , vol.67 , pp. 86-94
    • Ohnishi, T.1    Watanabe, A.2    Ohba, H.3
  • 121
    • 0038634052 scopus 로고    scopus 로고
    • Serotonin receptors in platelets of bipolar and schizo affective patients: Effect of lithium treatment
    • Pandey, G. N., Pandey, S. C., Ren, X., Dwivedi, Y., and Janicak, P. G. (2003) Serotonin receptors in platelets of bipolar and schizo affective patients: Effect of lithium treatment. Psychopharmacology 170: 115-123.
    • (2003) Psychopharmacology , vol.170 , pp. 115-123
    • Pandey, G.N.1    Pandey, S.C.2    Ren, X.3    Dwivedi, Y.4    Janicak, P.G.5
  • 122
    • 57649166962 scopus 로고    scopus 로고
    • Animal models of depression in dopamine, serotonin, and norepinephrine transporter knockout mice: Prominent Effects of dopamine transporter deletions
    • Perona, M. T., Waters, S., Hall, F. S., et al. (2008) Animal models of depression in dopamine, serotonin, and norepinephrine transporter knockout mice: Prominent Effects of dopamine transporter deletions. Behav Pharmacol 19: 566-574.
    • (2008) Behav Pharmacol , vol.19 , pp. 566-574
    • Perona, M.T.1    Waters, S.2    Hall, F.S.3
  • 123
  • 124
    • 33748280959 scopus 로고    scopus 로고
    • Transgenic mice overexpressing glycogen synthase kinase 3 beta: A putative model of hyperactivity and mania
    • Prickaerts, J., Moechars, D., Cryns, K., et al. (2006) Transgenic mice overexpressing glycogen synthase kinase 3 beta: A putative model of hyperactivity and mania. J Neurosci 26: 9022-9029.
    • (2006) J Neurosci , vol.26 , pp. 9022-9029
    • Prickaerts, J.1    Moechars, D.2    Cryns, K.3
  • 126
    • 0030807611 scopus 로고    scopus 로고
    • Fear decrease in transgenic mice overexpressing bcl-2 in neurons
    • Rondi-Reig, L., Lemaigre Dubreuil, Y., Martinou, J. C., et al. (1997) Fear decrease in transgenic mice overexpressing bcl-2 in neurons. Neuroreport 8: 2429-2432.
    • (1997) Neuroreport , vol.8 , pp. 2429-2432
    • Rondi-Reig, L.1    Lemaigre Dubreuil, Y.2    Martinou, J.C.3
  • 127
    • 34547498395 scopus 로고    scopus 로고
    • Mania-like behavior induced by disruption of CLOCK
    • Roybal, K., heobold, D., Graham, A., et al. (2007) Mania-like behavior induced by disruption of CLOCK. Proc Natl Acad Sci USA 104: 6406-6411.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 6406-6411
    • Roybal, K.1    Heobold, D.2    Graham, A.3
  • 128
    • 34248380127 scopus 로고    scopus 로고
    • Mineralocorticoid receptor overexpression in forebrain decreases anxiety-like behavior and alters the stress response in mice
    • Rozeboom, A. M., Akil, H., and Seasholtz, A. F. (2007) Mineralocorticoid receptor overexpression in forebrain decreases anxiety-like behavior and alters the stress response in mice. Proc Natl Acad Sci USA 104: 4688-4693.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 4688-4693
    • Rozeboom, A.M.1    Akil, H.2    Seasholtz, A.F.3
  • 129
    • 43049157802 scopus 로고    scopus 로고
    • Norepinephrine signaling through beta-adrenergic receptors is critical for expression of cocaine-induced anxiety
    • Schank, J. R., Liles, L. C., andWeinshenker, D. (2008) Norepinephrine signaling through beta-adrenergic receptors is critical for expression of cocaine-induced anxiety. Biol Psychiatry 63: 1007-1012.
    • (2008) Biol Psychiatry , vol.63 , pp. 1007-1012
    • Schank, J.R.1    Liles, L.C.2    Weinshenker, D.3
  • 130
    • 0016000449 scopus 로고
    • Biogenic amines and afective disorders
    • Schildkraut, J. J. (1974) Biogenic amines and afective disorders. Ann Rev Med 25: 333-348.
    • (1974) Ann Rev Med , vol.25 , pp. 333-348
    • Schildkraut, J.J.1
  • 131
    • 5544229693 scopus 로고    scopus 로고
    • Classic toxin-induced animal models of Parkinson’s disease: 6-OHDA and MPTP
    • Schober, A. (2004) Classic toxin-induced animal models of Parkinson’s disease: 6-OHDA and MPTP. Cell Tissue Res 318: 215-224.
    • (2004) Cell Tissue Res , vol.318 , pp. 215-224
    • Schober, A.1
  • 132
    • 0023254675 scopus 로고
    • Dopamine receptors and the dopamine hypothesis of schizophrenia
    • Seeman, P. (1987) Dopamine receptors and the dopamine hypothesis of schizophrenia. Synapse 1: 133-152.
    • (1987) Synapse , vol.1 , pp. 133-152
    • Seeman, P.1
  • 133
    • 47749156793 scopus 로고    scopus 로고
    • Thegenetics of bipolar disorder: Genome “hot regions, ” genes, new potential candidates and future directions
    • Serretti, A. and Mandelli, L. (2008) Thegenetics of bipolar disorder: Genome “hot regions, ” genes, new potential candidates and future directions. Mol Psychiatry 13: 742-771.
    • (2008) Mol Psychiatry , vol.13 , pp. 742-771
    • Serretti, A.1    Mandelli, L.2
  • 134
    • 34247137244 scopus 로고    scopus 로고
    • Behavioural phenotyping of sodium-myo-inositol cotransporter heterozygous knockout mice with reduced brain inositol
    • Shaldubina, A., Buccafusca, R., Johanson, R. A. et al. (2007) Behavioural phenotyping of sodium-myo-inositol cotransporter heterozygous knockout mice with reduced brain inositol. Genes Brain Behav 6: 253-259.
    • (2007) Genes Brain Behav , vol.6 , pp. 253-259
    • Shaldubina, A.1    Buccafusca, R.2    Johanson, R.A.3
  • 135
    • 33846933997 scopus 로고    scopus 로고
    • Neurotrophic signaling cascades in the pathophysiology and treatment of bipolar disorder
    • Shaltiel, G., Chen, G., and Manji, H. K. (2007) Neurotrophic signaling cascades in the pathophysiology and treatment of bipolar disorder. Curr Opin Pharmacol 7: 22-26.
    • (2007) Curr Opin Pharmacol , vol.7 , pp. 22-26
    • Shaltiel, G.1    Chen, G.2    Manji, H.K.3
  • 136
    • 49949086234 scopus 로고    scopus 로고
    • Evidence for the involvement of the kainate receptor subunit GluR6 (GRIK2) in mediating behavioral displays related to behavioral symptoms of mania
    • Shaltiel, G., Maeng, S., Malkesman, O., et al. (2008) Evidence for the involvement of the kainate receptor subunit GluR6 (GRIK2) in mediating behavioral displays related to behavioral symptoms of mania. Mol Psychiatry 13: 858-872.
    • (2008) Mol Psychiatry , vol.13 , pp. 858-872
    • Shaltiel, G.1    Maeng, S.2    Malkesman, O.3
  • 137
    • 9644276924 scopus 로고    scopus 로고
    • Valproate decreases inositol biosynthesis
    • Shaltiel, G., Shamir, A., Shapiro, J., et al. (2004) Valproate decreases inositol biosynthesis. Biol Psychiatry 56: 868-874.
    • (2004) Biol Psychiatry , vol.56 , pp. 868-874
    • Shaltiel, G.1    Shamir, A.2    Shapiro, J.3
  • 138
    • 3042763119 scopus 로고    scopus 로고
    • Examination of IMPA1 and IMPA2 genes in manic-depressive patients: Association between IMPA2 promoter polymorphisms and bipolar disorder
    • Sjoholt, G., Ebstein, R. P., Lie, R. T., et al. (2004) Examination of IMPA1 and IMPA2 genes in manic-depressive patients: Association between IMPA2 promoter polymorphisms and bipolar disorder. Mol Psychiatry 9: 621-629.
    • (2004) Mol Psychiatry , vol.9 , pp. 621-629
    • Sjoholt, G.1    Ebstein, R.P.2    Lie, R.T.3
  • 139
    • 0000685667 scopus 로고    scopus 로고
    • A human myo-inositol monophosphatase gene (IMPA2) localized in a putative susceptibility region for bipolar disorder on chromosome 18p11. 2: Genomic structure and polymorphism screening in manic-depressive patients
    • Sjoholt, G., Gulbrandsen, A. K., Lovlie, R., et al. (2000) A human myo-inositol monophosphatase gene (IMPA2) localized in a putative susceptibility region for bipolar disorder on chromosome 18p11. 2: Genomic structure and polymorphism screening in manic-depressive patients. Mol Psychiatry 5: 172-180.
    • (2000) Mol Psychiatry , vol.5 , pp. 172-180
    • Sjoholt, G.1    Gulbrandsen, A.K.2    Lovlie, R.3
  • 140
    • 30744463316 scopus 로고    scopus 로고
    • On construct validity: Issues of method and measurement
    • Smith, G. T. (2005) On construct validity: Issues of method and measurement. Psychol Assess 17: 396-408.
    • (2005) Psychol Assess , vol.17 , pp. 396-408
    • Smith, G.T.1
  • 141
    • 0032104267 scopus 로고    scopus 로고
    • Corticotropin releasing factor receptor 1-deicient mice display decreased anxiety, impaired stress response, and aberrant neuroendocrine development
    • Smith, G. W., Aubry, J. M., Dellu, F., et al. (1998) Corticotropin releasing factor receptor 1-deicient mice display decreased anxiety, impaired stress response, and aberrant neuroendocrine development. Neuron 20: 1093-1102.
    • (1998) Neuron , vol.20 , pp. 1093-1102
    • Smith, G.W.1    Aubry, J.M.2    Dellu, F.3
  • 142
    • 77951113131 scopus 로고    scopus 로고
    • Diferential association of circadian genes with mood disorders: CRY1 and NPAS2 are associated with unipolar major depression and CLOCK and VIP with bipolar disorder
    • Soria, V., Martinez-Amoros, E., Escaramis, G., et al. (2010) Diferential association of circadian genes with mood disorders: CRY1 and NPAS2 are associated with unipolar major depression and CLOCK and VIP with bipolar disorder. Neuropsychopharmacology 35: 1279-1289.
    • (2010) Neuropsychopharmacology , vol.35 , pp. 1279-1289
    • Soria, V.1    Martinez-Amoros, E.2    Escaramis, G.3
  • 144
    • 0027761105 scopus 로고
    • Injection of the protein kinase inhibitor H7 into the A10 dopamine region blocks the acute responses to cocaine: Behavioral and in vivo microdialysis studies
    • Steketee, J. D. (1993) Injection of the protein kinase inhibitor H7 into the A10 dopamine region blocks the acute responses to cocaine: Behavioral and in vivo microdialysis studies. Neuropharmacology 32: 1289-1297.
    • (1993) Neuropharmacology , vol.32 , pp. 1289-1297
    • Steketee, J.D.1
  • 145
    • 27144492384 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in bipolar disorder: Evidence from magnetic resonance spectroscopy research
    • Stork, C. and Renshaw, P. F. (2005) Mitochondrial dysfunction in bipolar disorder: Evidence from magnetic resonance spectroscopy research. Mol Psychiatry 10: 900-919.
    • (2005) Mol Psychiatry , vol.10 , pp. 900-919
    • Stork, C.1    Renshaw, P.F.2
  • 146
    • 77950579760 scopus 로고    scopus 로고
    • Construct validity: Advances in theory and methodology
    • Strauss, M. E. and Smith, G. T. (2008) Construct validity: Advances in theory and methodology. Ann Rev Clin Psychol 16: 16.
    • (2008) Ann Rev Clin Psychol , vol.16 , pp. 16
    • Strauss, M.E.1    Smith, G.T.2
  • 147
    • 71349083888 scopus 로고    scopus 로고
    • Involvement of NMDAR2A tyrosine phosphorylation in depression-related behaviour
    • Taniguchi, S., Nakazawa, T., Tanimura, A., et al. (2009) Involvement of NMDAR2A tyrosine phosphorylation in depression-related behaviour. EMBO J 28: 3717-3729.
    • (2009) EMBO J , vol.28 , pp. 3717-3729
    • Taniguchi, S.1    Nakazawa, T.2    Tanimura, A.3
  • 148
    • 2142827072 scopus 로고    scopus 로고
    • Neurobehavioral assessment in the information age
    • Tecott, L. H. and Nestler, E. J. (2004) Neurobehavioral assessment in the information age. Nat Neurosci 7: 462-466.
    • (2004) Nat Neurosci , vol.7 , pp. 462-466
    • Tecott, L.H.1    Nestler, E.J.2
  • 149
    • 17344362093 scopus 로고    scopus 로고
    • Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1
    • Timpl, P., Spanagel, R., Sillaber, I., et al. (1998) Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1. Nat Genet 19: 162-166.
    • (1998) Nat Genet , vol.19 , pp. 162-166
    • Timpl, P.1    Spanagel, R.2    Sillaber, I.3
  • 150
    • 0017646652 scopus 로고
    • Olfactory bulb ablation in the rat: Behavioural changes and their reversal by antidepressant drugs
    • Van Riezen, H., Schnieden, H., andWren, A. F. (1977) Olfactory bulb ablation in the rat: Behavioural changes and their reversal by antidepressant drugs. Br J Pharmacol 60: 521-528.
    • (1977) Br J Pharmacol , vol.60 , pp. 521-528
    • Van Riezen, H.1    Schnieden, H.2    Wren, A.F.3
  • 151
    • 79953283718 scopus 로고    scopus 로고
    • Increased anxiety-related behaviour in Hint1 knockout mice
    • Varadarajulu, J., Lebar, M., Krishnamoorthy, G., et al. (2011) Increased anxiety-related behaviour in Hint1 knockout mice. Behav Brain Res 220: 305-311.
    • (2011) Behav Brain Res , vol.220 , pp. 305-311
    • Varadarajulu, J.1    Lebar, M.2    Krishnamoorthy, G.3
  • 152
    • 2642581632 scopus 로고    scopus 로고
    • Hypothalamic-pituitary-adrenal axis function in patients with bipolar disorder
    • Watson, S., Gallagher, P., Ritchie, J. C., Ferrier, I. N., and Young, A. H. (2004) Hypothalamic-pituitary-adrenal axis function in patients with bipolar disorder. Br J Psychiatry 184: 496-502.
    • (2004) Br J Psychiatry , vol.184 , pp. 496-502
    • Watson, S.1    Gallagher, P.2    Ritchie, J.C.3    Ferrier, I.N.4    Young, A.H.5
  • 153
    • 0020072603 scopus 로고
    • 48-hour sleep-wake cycles in manic-depressive illness: Naturalistic observations and sleep deprivation experiments
    • Wehr, T. A., Goodwin, F. K., Wirz-Justice, A., Breitmaier, J., and Craig, C. (1982) 48-hour sleep-wake cycles in manic-depressive illness: Naturalistic observations and sleep deprivation experiments. Arch Gen Psychiatry 39: 559-565.
    • (1982) Arch Gen Psychiatry , vol.39 , pp. 559-565
    • Wehr, T.A.1    Goodwin, F.K.2    Wirz-Justice, A.3    Breitmaier, J.4    Craig, C.5
  • 154
    • 0023094678 scopus 로고
    • Sleep reduction as a inal common pathway in the genesis of mania
    • Wehr, T. A., Sack, D. A., and Rosenthal, N. E. (1987) Sleep reduction as a inal common pathway in the genesis of mania. Am J Psychiatry 144: 201-204.
    • (1987) Am J Psychiatry , vol.144 , pp. 201-204
    • Wehr, T.A.1    Sack, D.A.2    Rosenthal, N.E.3
  • 155
    • 84855427150 scopus 로고    scopus 로고
    • Early-life forebrain glucocorticoid receptor overexpression increases anxiety behavior and cocaine sensitization
    • Wei, Q., Fentress, H. M., Hoversten, M. T., et al. (2012) Early-life forebrain glucocorticoid receptor overexpression increases anxiety behavior and cocaine sensitization. Biol Psychiatry 71: 224-231.
    • (2012) Biol Psychiatry , vol.71 , pp. 224-231
    • Wei, Q.1    Fentress, H.M.2    Hoversten, M.T.3
  • 156
    • 4143091546 scopus 로고    scopus 로고
    • Glucocorticoid receptor overexpression in forebrain: A mouse model of increased emotional lability
    • Wei, Q., Lu, X. Y., Liu, L., et al. (2004) Glucocorticoid receptor overexpression in forebrain: A mouse model of increased emotional lability. Proc Natl Acad Sci USA 101: 11851-11856.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 11851-11856
    • Wei, Q.1    Lu, X.Y.2    Liu, L.3
  • 158
    • 0037118050 scopus 로고    scopus 로고
    • A common mechanism of action for three mood-stabilizing drugs
    • Williams, R. S., Cheng, L., Mudge, A. W., and Harwood, A. J. (2002) A common mechanism of action for three mood-stabilizing drugs. Nature 417: 292-295.
    • (2002) Nature , vol.417 , pp. 292-295
    • Williams, R.S.1    Cheng, L.2    Mudge, A.W.3    Harwood, A.J.4
  • 159
    • 0021348560 scopus 로고
    • The validity of animal models of depression
    • Willner, P. (1984) The validity of animal models of depression. Psychopharmacology 83: 1-16.
    • (1984) Psychopharmacology , vol.83 , pp. 1-16
    • Willner, P.1
  • 160
    • 0023000704 scopus 로고
    • Validation criteria for animal models of human mental disorders: Learned helplessness as a paradigm case
    • Willner, P. (1986) Validation criteria for animal models of human mental disorders: Learned helplessness as a paradigm case. Prog Neuropsychopharmacol Biol Psychiatry 10: 677-690.
    • (1986) Prog Neuropsychopharmacol Biol Psychiatry , vol.10 , pp. 677-690
    • Willner, P.1
  • 161
    • 0025057433 scopus 로고
    • Animal models of depression: An overview
    • Willner, P. (1990) Animal models of depression: An overview. Pharmacolher 45: 425-455.
    • (1990) Pharmacolher , vol.45 , pp. 425-455
    • Willner, P.1
  • 162
    • 0026020342 scopus 로고
    • Animal models as simulations of depression
    • Willner, P. (1991a) Animal models as simulations of depression. Trends Pharmacol Sci 12: 131-136.
    • (1991) Trends Pharmacol Sci , vol.12 , pp. 131-136
    • Willner, P.1
  • 164
    • 0029188187 scopus 로고
    • Animal models of depression: Validity and applications
    • Willner, P. (1995a) Animal models of depression: Validity and applications. Adv Biochem Psychopharmacol 49: 19-41.
    • (1995) Adv Biochem Psychopharmacol , vol.49 , pp. 19-41
    • Willner, P.1
  • 165
    • 0001780547 scopus 로고
    • Animal models of depression: Validity and applications
    • G. L. Gessa, W. Fratta, L. Pani, and G. Serra (eds), NewYork: Raven Press
    • Willner, P. (1995b) Animal models of depression: Validity and applications. In G. L. Gessa, W. Fratta, L. Pani, and G. Serra (eds) Depression and Mania: From Neurobiology to Treatment. NewYork: Raven Press.
    • (1995) Depression and Mania: From Neurobiology to Treatment
    • Willner, P.1
  • 166
    • 0026440178 scopus 로고
    • Chronic mild stress-induced anhedonia: A realistic animal model of depression
    • Willner, P., Muscat, R., and Papp, M. (1992) Chronic mild stress-induced anhedonia: A realistic animal model of depression. Neurosci Biobehav Rev 16: 525-534.
    • (1992) Neurosci Biobehav Rev , vol.16 , pp. 525-534
    • Willner, P.1    Muscat, R.2    Papp, M.3
  • 167
    • 0034106576 scopus 로고    scopus 로고
    • Nordidemnin potently inhibits inositol uptake in cultured astrocytes and dose-dependently augments lithium’s proconvulsant efect in vivo
    • Wolfson, M., Einat, H., Bersudsky, Y., et al. (2000) Nordidemnin potently inhibits inositol uptake in cultured astrocytes and dose-dependently augments lithium’s proconvulsant efect in vivo. J Neurosci Res 60: 116-121.
    • (2000) J Neurosci Res , vol.60 , pp. 116-121
    • Wolfson, M.1    Einat, H.2    Bersudsky, Y.3
  • 168
    • 80053195122 scopus 로고    scopus 로고
    • Valproic acid inducesmonoamine oxidase A via Akt/forkhead box O1 activation
    • Wu, J. B. and Shih, J. C. (2011) Valproic acid inducesmonoamine oxidase A via Akt/forkhead box O1 activation. Mol Pharmacol 80: 714-723.
    • (2011) Mol Pharmacol , vol.80 , pp. 714-723
    • Wu, J.B.1    Shih, J.C.2
  • 169
    • 0033915420 scopus 로고    scopus 로고
    • Mice lacking the norepinephrine transporter are supersensitive to psychostimulants
    • Xu, F., Gainetdinov, R. R., Wetsel, W. C., et al. (2000) Mice lacking the norepinephrine transporter are supersensitive to psychostimulants. Nat Neurosci 3: 465-471.
    • (2000) Nat Neurosci , vol.3 , pp. 465-471
    • Xu, F.1    Gainetdinov, R.R.2    Wetsel, W.C.3
  • 170
    • 0037209045 scopus 로고    scopus 로고
    • Dose-related Effects of chronic antidepressants on neuroprotective proteins BDNF, Bcl-2 and Cu/Zn-SOD in rat hippocampus
    • Xu, H., Richardson, S. J., and Li, X. M. (2003) Dose-related Effects of chronic antidepressants on neuroprotective proteins BDNF, Bcl-2 and Cu/Zn-SOD in rat hippocampus. Neuropsychopharmacology 28: 53-62.
    • (2003) Neuropsychopharmacology , vol.28 , pp. 53-62
    • Xu, H.1    Richardson, S.J.2    Li, X.M.3
  • 171
    • 84863279487 scopus 로고    scopus 로고
    • Deletion of glutamate delta-1 receptor in mouse leads to aberrant emotional and social behaviors
    • Yadav, R., Gupta, S. C., Hillman, B. G., et al. (2012) Deletion of glutamate delta-1 receptor in mouse leads to aberrant emotional and social behaviors. PLoS One 7: E32969.
    • (2012) Plos One , vol.7
    • Yadav, R.1    Gupta, S.C.2    Hillman, B.G.3
  • 172
    • 34548009382 scopus 로고    scopus 로고
    • Lithium regulates hippocampal neurogenesis by ERK pathway and facilitates recovery of spatial learning and memory in rats ater transient global cerebral ischemia
    • Yan, X. B., Hou, H. L., Wu, L. M., Liu, J., and Zhou, J. N. (2007) Lithium regulates hippocampal neurogenesis by ERK pathway and facilitates recovery of spatial learning and memory in rats ater transient global cerebral ischemia. Neuropharmacology 53: 487-495.
    • (2007) Neuropharmacology , vol.53 , pp. 487-495
    • Yan, X.B.1    Hou, H.L.2    Wu, L.M.3    Liu, J.4    Zhou, J.N.5
  • 173
    • 40349093181 scopus 로고    scopus 로고
    • Protein kinase C inhibition in the treatment of mania: A double-blind, placebo-controlled trial of tamoxifen
    • Yildiz, A., Guleryuz, S., Ankerst, D. P., Ongur, D., and Renshaw, P. F. (2008) Protein kinase C inhibition in the treatment of mania: A double-blind, placebo-controlled trial of tamoxifen. Arch Gen Psychiatry 65: 255-263.
    • (2008) Arch Gen Psychiatry , vol.65 , pp. 255-263
    • Yildiz, A.1    Guleryuz, S.2    Ankerst, D.P.3    Ongur, D.4    Renshaw, P.F.5
  • 174
    • 34548026980 scopus 로고    scopus 로고
    • A reverse-translational approach to bipolar disorder: Rodent and human studies in the Behavioral Pattern Monitor
    • Young, J. W., Minassian, A., Paulus, M. P., Geyer, M. A., and Perry, W. (2007) A reverse-translational approach to bipolar disorder: Rodent and human studies in the Behavioral Pattern Monitor. Neurosci Biobehav Rev 31: 882-896.
    • (2007) Neurosci Biobehav Rev , vol.31 , pp. 882-896
    • Young, J.W.1    Minassian, A.2    Paulus, M.P.3    Geyer, M.A.4    Perry, W.5
  • 175
    • 0035943699 scopus 로고    scopus 로고
    • The mood stabilizer valproic acid activates mitogen-activated protein kinases and promotes neurite growth
    • Yuan, P. X., Huang, L. D., Jiang, Y. M., et al. (2001) The mood stabilizer valproic acid activates mitogen-activated protein kinases and promotes neurite growth. J Biol Chem 276: 31674-31683.
    • (2001) J Biol Chem , vol.276 , pp. 31674-31683
    • Yuan, P.X.1    Huang, L.D.2    Jiang, Y.M.3
  • 176
    • 0347722453 scopus 로고    scopus 로고
    • Regulation of cellular plasticity cascades in the pathophysiology and treatment of mood disorders: Role of the glutamatergic system
    • Zarate, C. A., Jr., Du, J., Quiroz, J., et al. (2003) Regulation of cellular plasticity cascades in the pathophysiology and treatment of mood disorders: Role of the glutamatergic system. Ann NY Acad Sci 1003: 273-291.
    • (2003) Ann NY Acad Sci , vol.1003 , pp. 273-291
    • Zarate, C.A.1    Du, J.2    Quiroz, J.3
  • 177
    • 33746896935 scopus 로고    scopus 로고
    • A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression
    • Zarate, C. A., Jr., Singh, J. B., Carlson, P. J., et al. (2006) A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression. Arch Gen Psychiatry 63: 856-864.
    • (2006) Arch Gen Psychiatry , vol.63 , pp. 856-864
    • Zarate, C.A.1    Singh, J.B.2    Carlson, P.J.3
  • 178
    • 34548403443 scopus 로고    scopus 로고
    • Eicacy of a protein kinase C inhibitor (Tamoxifen) in the treatment of acute mania: A pilot study
    • Zarate, C. A., Jr., Singh, J. B., Carlson, P. J., et al. (2007) Eicacy of a protein kinase C inhibitor (tamoxifen) in the treatment of acute mania: A pilot study. Bipolar Disord 9: 561-570.
    • (2007) Bipolar Disord , vol.9 , pp. 561-570
    • Zarate, C.A.1    Singh, J.B.2    Carlson, P.J.3
  • 179
    • 0242490254 scopus 로고    scopus 로고
    • Forebrain-specific trkB-receptor knockout mice: Behaviorally more hyperactive than “depressive. ”
    • Zorner, B., Wolfer, D. P., Brandis, D., et al. (2003) Forebrain-specific trkB-receptor knockout mice: Behaviorally more hyperactive than “depressive. ” Biol Psychiatry 54: 972-982.
    • (2003) Biol Psychiatry , vol.54 , pp. 972-982
    • Zorner, B.1    Wolfer, D.P.2    Brandis, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.