Mood disorder susceptibility gene CACNA1C modifies mood-related behaviors in mice and interacts with sex to influence behavior in mice and diagnosis in humans

Biological Psychiatry

Volumn 68, Issue 9, 2010, Pages 801-810

  Dao, David T ^a   Mahon, Pamela Belmonte ^b   Cai, Xiang ^a   Kovacsics, Colleen E ^a   Blackwell, Robert A ^a   Arad, Michal ^a   Shi, Jianxin ^c   Zandi, Peter P ^b   O'Donnell, Patricio ^a   Knowles, James A ^d   Weissman, Myrna M ^e   Coryell, William ^f   Scheftner, William A ^g   Lawson, William B ^h   Levinson, Douglas F ^c   Thompson, Scott M ^a   Potash, James B ^b   Gould, Todd D ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c STANFORD UNIVERSITY   (United States)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^e Och Spine at New York Presbyterian Hospitals   (United States)

^f UNIVERSITY OF IOWA   (United States)

^g RUSH UNIVERSITY   (United States)

^h HOWARD UNIVERSITY   (United States)

Author keywords

Animal model; bipolar disorder; CaV1.2; CACNA1C; gender; major depression; sex differences

Indexed keywords

AMPHETAMINE; CALCIUM CHANNEL L TYPE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY; ARTICLE; BEHAVIOR; BIPOLAR DEPRESSION; CONTROLLED STUDY; DEPRESSION; DNA MODIFICATION; EXPLORATORY BEHAVIOR; FEMALE; FORCED SWIMMING TEST; GENE DELETION; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; HABITUATION; HETEROZYGOTE; HYPERACTIVITY; INTRON; LEARNED HELPLESSNESS; MALE; MOOD DISORDER; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; SEX DIFFERENCE; SINGLE NUCLEOTIDE POLYMORPHISM; STARTLE REFLEX; TREATMENT RESPONSE;

ANIMALS; BEHAVIOR, ANIMAL; CALCIUM CHANNELS, L-TYPE; DEXTROAMPHETAMINE; DISEASE MODELS, ANIMAL; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HAPLOINSUFFICIENCY; HETEROZYGOTE; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOOD DISORDERS; POLYMORPHISM, SINGLE NUCLEOTIDE; SEX CHARACTERISTICS;

EID: 77957900975     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsych.2010.06.019     Document Type: Article

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