Evaluation of nigrostriatal dopaminergic function in adult +/+ and +/- BDNF mutant mice

Experimental Neurology

Volumn 170, Issue 1, 2001, Pages 121-128

  Dluzen, Dean E ^a   Gao, Xuemei ^a   Story, Gina M ^a   Anderson, Linda I ^a   Kucera, Jan ^b   Walro, Jon M ^a  

^a Northeastern Ohio Medical University   (United States)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Amphetamine; Brain derived neurotrophic factor; Corpus striatum; Dopamine; Locomotor activity; Methamphetamine; Neurotrophins; Sensorimotor

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; DOPAMINE; METHAMPHETAMINE; NEUROTOXIN; NEUROTROPHIC FACTOR; NORADRENALIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINERGIC SYSTEM; GENE DELETION; HYPOTHALAMUS; LOCOMOTION; MOUSE; NONHUMAN; OLFACTORY BULB; PRIORITY JOURNAL; SENSORIMOTOR FUNCTION;

EID: 0034948210     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.2001.7698     Document Type: Article

References (52)

1. BDNF gene transcripts in mesencephalic neurons and its differential regulation by NMDA
2. Anterograde transport of brain-derived neurotrophic factor and its role in the brain
3. The nature of the trophic action of brain-derived neurotrophic factor, des(1-3)-insulin-like growth factor-1 and basic fibroblast growth factor on mesencephalic dopaminergic neurons developing in culture
4. The influence of estrous cycle and intrastriatal estradiol on sensorimotor performance in the female rat
5. Degeneration of vestibular neurons in late embryogenesis of both heterozygous and homozygous BDNF null mutant mice
6. Lntr receptors
7. Role of dopamine autoxidation, hydroxyl radical generation and calcium overload in underlying mechanisms in MPTP-induced Parkinsonism
8. In vivo generation of hydroxyl radicals and MPTP-induced dopaminergic toxicity in the basal ganglia
9. Distribution of brain-derived neurotrophic factor (BDNF) protein and mRNA in normal adult rat CNS: Evidence for anterograde axonal transport
10. Neuronal deficits, not involving motor neurons, in mice lacking BDNF and/or NT4
11. Neurotrophin regulation of the developing nervous system: Analysis of knockout mice
12. Expression of BDNF and trkB as a function of age and cognitive performance
13. Estrogen reduces acute striatal dopamine responses in vivo to the neurotoxin MPP+ in female, but not male rats
14. Age-related changes in monoamines within the olfactory bulbs of the Fischer 344 male rat
15. Daily spontaneous running alters behavioral and neurochemical indices of nigrostriatal function
16. Effects of orchidectomy on nigro-striatal dopanminergic function: Behavioral and physiological evidence
17. In vivo changes in responsiveness of the caudate nucleus to L-DOPA infusion as a function of the estrous cycle
18. Alterations in nigrostriatal dopaminergic function within BDNF mutant mice
19. A new motor test sensitive to aging and dopaminergic function
20. Mice lacking brain derived neurotrophic factor develop with sensory deficits
21. Age related decline in the dopaminergic nigrostriatal system: The oxidative hypothesis and protective strategies
22. Differential effects of GDNF and BDNF on cultured ventral mesencephalic neurons
23. Pre- and postsynaptic neurotoxic effects of dopamine demonstrated by intrastriatal injection
24. Transient and persistent expression of NT-3/BDNF mRNA in the rat brain during postnatal development
25. Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain
26. Rat fetal mesencephalon grown as solid tissue cultures: Influence of culture time and BDNF treatment on dopamine neuron survival and function
27. Enhancement of locomotor activity and conditioned reward to cocaine by brain-derived neurotrophic factor
28. BDNF expression in Parkinson's Disease substantia nigra
29. BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra
30. Overlapping and distinct actions of the neurotrophins BDNF, NT-3, and NT-4/5 on cultured dopaminergic and GABAergic neurons of the ventral mesencephalon
31. Age related changes in levels of brain-derived neurotrophic factor in selected brain regions of rats, normal mice and senescence-accelerated mice: A comparison to those of nerve growth factor and neurotrophin-3
32. Promotion of central cholinergic and dopaminergic neuron differentiation by brain-derived neurotrophic factor but not neurotrophin 3
33. Brain-derived neurotrophic factor levels in the nervous system of wild-type and neurotrophin gene mutant mice
34. Modulation of nigrostriatal dopaminergic transmission by antisense oligodeoxynucleotide against brain-derived neurotrophic factor
35. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
36. Consideration of sensory factors involved in motor functions of the basal ganglia
37. Sensory but not motor neuron deficits in mice lacking NT4 and BDNF
38. NT-3, BDNF, and NGF in the developing rat nervous system: Parallel as well as reciprocal patterns of expression
39. Effects of estrogen treatment on sensorimotor task performance and brain dopamine concentrations in gonadectomized male and female CD-1 mice
40. Nerve growth factor treatment increases brain-derived neurotrophic factor selectivity in TrkA-expressing dorsal root ganglion cells and in their central terminations within the spinal cord
41. Toxicity of 6-hydroxydopamine for dopaminergic neurons in culture
42. A scientific rationale for protective therapy in Parkinson's disease
43. Dopaminergic stimulation up-regulates the in vivo expression of brain-derived neurotrophic factor (BDNF) in the striatum
44. Reduced expression of brain-derived neurotrophic factor protein in Parkinson's disease substantia nigra
45. Compensatory changes in striatal dopamine neurons following recovery from injury induced by 6-OHDA or methamphetamine: A review of evidence from microdialysis studies
46. Effects of combined BDNF and GDNF treatment on cultured dopaminergic midbrain neurons
47. Effects of BDNF on dopaminergic, serotonergic and GABAergic neurons in cultures of fetal ventral mesencephalon
48. Inhalation of low concentrations of toluene induces persistent effects on a learning retention task, beam-walk performance, and cerebrocortical size in the rat
49. Lesion-induced increase of BDNF is greater in the striatum of young versus old rat brain
50. The response of human and rat fetal mesencephalon in culture to the brain-derived neurotrophic factor treatment
51. Endogenous brain-derived neurotrophic factor is anteriorly transported in primary sensory neurons
52. Neurochemical Responses to 6-hydroxydopamine and L-DOPA therapy: Implications for Parkinson's disease