Mutant AKT1-E17K is oncogenic in lung epithelial cells

Oncotarget

Volumn 6, Issue 37, 2015, Pages 39634-39650

  De Marco, Carmela ^a,b   Malanga, Donatella ^a,b   Rinaldo, Nicola ^b   De Vita, Fernanda ^b   Scrima, Marianna ^b   Lovisa, Sara ^c   Fabris, Linda ^c   Carriero, Maria Vincenza ^d   Franco, Renato ^d   Rizzuto, Antonia ^a   Baldassarre, Gustavo ^c   Viglietto, Giuseppe ^a,b  

^a UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

^b Grande Ospedale Metropolitano   (Italy)

^c CENTRO DI RIFERIMENTO ONCOLOGICO   (Italy)

^d NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

AKT1 E17K; Human lung epithelial cells; Lung cancer; P27

Indexed keywords

AKT1 PROTEIN; E17K PROTEIN; MUTANT PROTEIN; ONCOPROTEIN; PROTEIN P27; UNCLASSIFIED DRUG; CYCLIN DEPENDENT KINASE INHIBITOR 1B; PROTEIN KINASE B;

ARTICLE; BEAS 2B CELL; BRONCHUS MUCOSA; CANCER SURVIVAL; CARCINOGENESIS; CELL ADHESION; CELL DIVISION; CELL MIGRATION; CELL PROLIFERATION; CELL STRESS; CELL SURVIVAL; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; DISEASE ACTIVITY; ENZYME PHOSPHORYLATION; EPITHELIUM CELL; HUMAN; HUMAN CELL; IMMORTALIZED CELL LINE; LUNG ALVEOLUS EPITHELIUM CELL; LUNG TUMOR; NON SMALL CELL LUNG CANCER; NONHUMAN; PROTEIN FUNCTION; ANIMAL; BRONCHUS; CELL LINE; CELL MOTION; CYTOLOGY; FLUORESCENCE MICROSCOPY; GENETICS; KAPLAN MEIER METHOD; METABOLISM; MIDDLE AGED; MISSENSE MUTATION; NUDE MOUSE; PATHOLOGY; PHOSPHORYLATION; PROGNOSIS; TIME LAPSE IMAGING; TUMOR CELL LINE; WESTERN BLOTTING; XENOGRAFT;

ANIMALS; BLOTTING, WESTERN; BRONCHI; CELL ADHESION; CELL LINE; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; CYCLIN-DEPENDENT KINASE INHIBITOR P27; EPITHELIAL CELLS; HUMANS; KAPLAN-MEIER ESTIMATE; LUNG NEOPLASMS; MICE, NUDE; MICROSCOPY, FLUORESCENCE; MIDDLE AGED; MUTATION, MISSENSE; PHOSPHORYLATION; PROGNOSIS; PROTO-ONCOGENE PROTEINS C-AKT; TIME-LAPSE IMAGING; TRANSPLANTATION, HETEROLOGOUS;

EID: 84950161642     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.4022     Document Type: Article

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