Functional analysis of non-hotspot AKT1 mutants found in human breast cancers identifies novel driver mutations: Implications for personalized medicine

Oncotarget

Volumn 4, Issue 1, 2013, Pages 29-34

  Yi, Kyung H ^a   Axtmayer, Jossette ^a,b   Gustin, John P ^a   Rajpurohit, Anandita ^a   Lauring, Josh ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b PONCE SCHOOL OF MEDICINE   (Puerto Rico)

Author keywords

AKT1; Cancer; Mutation; Personalized; Therapy

Indexed keywords

AKT1 PROTEIN; CELL PROTEIN; PROTEIN KINASE B; PROTEIN PRAS40; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR FKHRL1; UNCLASSIFIED DRUG;

AKT1 GENE; ANIMAL CELL; ARTICLE; BREAST CANCER; CANCER THERAPY; CELL ASSAY; CELL TRANSFORMATION; ENZYME ACTIVATION; GENE FUNCTION; GENE MUTATION; GENE SEQUENCE; HUMAN; HUMAN CELL; MUTATIONAL ANALYSIS; NONHUMAN; PERSONALIZED MEDICINE; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; RAT; SEQUENCE HOMOLOGY;

EID: 84875799044     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.755     Document Type: Article

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