메뉴 건너뛰기




Volumn 22, Issue 7, 2011, Pages 1507-1519

Metastatic non-small-cell lung cancer: Consensus on pathology and molecular tests, first-line, second-line, and third-line therapy 1st ESMO Consensus Conference in Lung Cancer; Lugano 2010

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; BEVACIZUMAB; BRCA1 PROTEIN; CARBOPLATIN; CETUXIMAB; CISPLATIN; CRIZOTINIB; DOCETAXEL; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; ERLOTINIB; EXCISION REPAIR CROSS COMPLEMENTING PROTEIN 1; GEMCITABINE; K RAS PROTEIN; MESSENGER RNA; MITOMYCIN; NAVELBINE; ONCOPROTEIN; PACLITAXEL; PEMETREXED; PLACEBO; PLATINUM COMPLEX; PROTEIN PIK3CA; PROTEIN RRM1; PROTEIN TS; UNCLASSIFIED DRUG; VINBLASTINE;

EID: 79959703683     PISSN: 09237534     EISSN: 15698041     Source Type: Journal    
DOI: 10.1093/annonc/mdr150     Document Type: Article
Times cited : (113)

References (78)
  • 1
    • 0035879607 scopus 로고    scopus 로고
    • Summary of the guidelines for preventing opportunistic infections among hematopoietic stem cell transplant recipients
    • Dykewicz CA. Summary of the guidelines for preventing opportunistic infections among hematopoietic stem cell transplant recipients. Clin Infect Dis 2001; 33: 139-144.
    • (2001) Clin Infect Dis , vol.33 , pp. 139-144
    • Dykewicz, C.A.1
  • 2
    • 77949957365 scopus 로고    scopus 로고
    • Cell line-based platforms to evaluate the therapeutic efficacy of candidate anticancer agents
    • Sharma SV, Haber DA, Settleman J. Cell line-based platforms to evaluate the therapeutic efficacy of candidate anticancer agents. Nat Rev Cancer 2010; 10: 241-253.
    • (2010) Nat Rev Cancer , vol.10 , pp. 241-253
    • Sharma, S.V.1    Haber, D.A.2    Settleman, J.3
  • 3
    • 69949186250 scopus 로고    scopus 로고
    • Screening for epidermal growth factor receptor mutations in lung cancer
    • Rosell R, Moran T, Queralt C et al. Screening for epidermal growth factor receptor mutations in lung cancer. N Engl J Med 2009; 361: 958-967.
    • (2009) N Engl J Med , vol.361 , pp. 958-967
    • Rosell, R.1    Moran, T.2    Queralt, C.3
  • 4
    • 69949162760 scopus 로고    scopus 로고
    • Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
    • Mok TS, Wu YL, Thongprasert S et al. Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. N Engl J Med 2009; 361: 947-957.
    • (2009) N Engl J Med , vol.361 , pp. 947-957
    • Mok, T.S.1    Wu, Y.L.2    Thongprasert, S.3
  • 5
    • 75249087060 scopus 로고    scopus 로고
    • Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial
    • Mitsudomi T, Morita S, Yatabe Y et al. Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial. Lancet Oncol 2010; 11: 121-128.
    • (2010) Lancet Oncol , vol.11 , pp. 121-128
    • Mitsudomi, T.1    Morita, S.2    Yatabe, Y.3
  • 6
    • 77953930730 scopus 로고    scopus 로고
    • Gefitinib or chemotherapy for non small cell lung cancer with mutated tumour
    • Maemondo M, Inoue A, Kobayashi K et al. Gefitinib or chemotherapy for non small cell lung cancer with mutated tumour. N Engl J Med 2010; 362: 2380-2388.
    • (2010) N Engl J Med , vol.362 , pp. 2380-2388
    • Maemondo, M.1    Inoue, A.2    Kobayashi, K.3
  • 7
    • 77958478674 scopus 로고    scopus 로고
    • Rational, biologically based treatment of EGFR-mutant non-small-cell lung cancer
    • Pao W, Chmielecki J. Rational, biologically based treatment of EGFR-mutant non-small-cell lung cancer. Nat Rev Cancer 2010; 10: 760-774.
    • (2010) Nat Rev Cancer , vol.10 , pp. 760-774
    • Pao, W.1    Chmielecki, J.2
  • 8
    • 77958185649 scopus 로고    scopus 로고
    • Consensus for EGFR mutation testing in nonsmall cell lung cancer: results from a European workshop
    • Pirker R, Herth FJ, Kerr KM et al. Consensus for EGFR mutation testing in nonsmall cell lung cancer: results from a European workshop. J Thorac Oncol 2010; 5: 1706-1713.
    • (2010) J Thorac Oncol , vol.5 , pp. 1706-1713
    • Pirker, R.1    Herth, F.J.2    Kerr, K.M.3
  • 9
    • 76149086520 scopus 로고    scopus 로고
    • Endobronchial ultrasound-guided transbronchial needle aspiration for identifying EGFR mutations
    • Garcia-Olive I, Monso E, Andreo F et al. Endobronchial ultrasound-guided transbronchial needle aspiration for identifying EGFR mutations. Eur Respir J 2010; 35: 391-395.
    • (2010) Eur Respir J , vol.35 , pp. 391-395
    • Garcia-Olive, I.1    Monso, E.2    Andreo, F.3
  • 10
    • 77950999338 scopus 로고    scopus 로고
    • Pathologic diagnosis of advanced lung cancer based on small biopsies and cytology: a paradigm shift
    • Travis WD, Rekhtman N, Riley GJ et al. Pathologic diagnosis of advanced lung cancer based on small biopsies and cytology: a paradigm shift. J Thorac Oncol 2010; 5: 411-414.
    • (2010) J Thorac Oncol , vol.5 , pp. 411-414
    • Travis, W.D.1    Rekhtman, N.2    Riley, G.J.3
  • 11
    • 74749089695 scopus 로고    scopus 로고
    • Core needle lung biopsy specimens: adequacy for EGFR and KRAS mutational analysis
    • Solomon SB, Zakowski MF, Pao W et al. Core needle lung biopsy specimens: adequacy for EGFR and KRAS mutational analysis. AJR Am J Roentgenol 2010; 194: 266-269.
    • (2010) AJR Am J Roentgenol , vol.194 , pp. 266-269
    • Solomon, S.B.1    Zakowski, M.F.2    Pao, W.3
  • 12
    • 46249096082 scopus 로고    scopus 로고
    • Lung adenocarcinoma: modification of the 2004 WHO mixed subtype to include the major histologic subtype suggests correlations between papillary and micropapillary adenocarcinoma subtypes. EGFR mutations and gene expression analysis
    • Motoi N, Szoke J, Riely GJ et al. Lung adenocarcinoma: modification of the 2004 WHO mixed subtype to include the major histologic subtype suggests correlations between papillary and micropapillary adenocarcinoma subtypes, EGFR mutations and gene expression analysis. Am J Surg Pathol 2008; 32: 810-827.
    • (2008) Am J Surg Pathol , vol.32 , pp. 810-827
    • Motoi, N.1    Szoke, J.2    Riely, G.J.3
  • 13
    • 79551563284 scopus 로고    scopus 로고
    • International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society International Multidisciplinary classification of lung adenocarcinoma
    • Travis WD, Brambilla E, Noguchi M et al. International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society International Multidisciplinary classification of lung adenocarcinoma. J Thorac Oncol 2011; 5: 244-285.
    • (2011) J Thorac Oncol , vol.5 , pp. 244-285
    • Travis, W.D.1    Brambilla, E.2    Noguchi, M.3
  • 14
    • 58449083554 scopus 로고    scopus 로고
    • Pulmonary adenocarcinomas: classification and reporting
    • Kerr KM. Pulmonary adenocarcinomas: classification and reporting. Histopathology 2009; 54: 12-27.
    • (2009) Histopathology , vol.54 , pp. 12-27
    • Kerr, K.M.1
  • 15
    • 2342624080 scopus 로고    scopus 로고
    • EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy
    • Paez JG, Jä nne PA, Lee JC et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 2004; 304: 1497-1500.
    • (2004) Science , vol.304 , pp. 1497-1500
    • Paez, J.G.1    Jä nne, P.A.2    Lee, J.C.3
  • 16
    • 2342471392 scopus 로고    scopus 로고
    • Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
    • Lynch TJ, Bell DW, Sordella R et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004; 350: 2129-2139.
    • (2004) N Engl J Med , vol.350 , pp. 2129-2139
    • Lynch, T.J.1    Bell, D.W.2    Sordella, R.3
  • 17
    • 4444344330 scopus 로고    scopus 로고
    • EGF receptor gene mutations are common in lung cancers from "ever smokers"and are associated with sensitivity of tumors to gefitinib and erlotinib
    • Pao W, Miller V, Zakowski M et al. EGF receptor gene mutations are common in lung cancers from "ever smokers"and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci U S A 2004; 101: 13306-13311.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 13306-13311
    • Pao, W.1    Miller, V.2    Zakowski, M.3
  • 18
    • 78049353345 scopus 로고    scopus 로고
    • Outcome to erlotinib in non-small-cell lung cancer (NSCLC) patients (p) according to the presence of the EGFR T790M mutation and BRCA1 mRNA expression levels in pretreatment biopsies
    • (Abstr 7514)
    • Rosell R, Molina M, Costa C et al. Outcome to erlotinib in non-small-cell lung cancer (NSCLC) patients (p) according to the presence of the EGFR T790M mutation and BRCA1 mRNA expression levels in pretreatment biopsies. J Clin Oncol 2010; 28: 542s (Abstr 7514).
    • (2010) J Clin Oncol , vol.28 , Issue.542 S
    • Rosell, R.1    Molina, M.2    Costa, C.3
  • 19
    • 33748074447 scopus 로고    scopus 로고
    • Presence of epidermal growth factor receptor gene T790M mutation as a minor clone in non-small cell lung cancer
    • Inukai M, Toyooka S, Ito S et al. Presence of epidermal growth factor receptor gene T790M mutation as a minor clone in non-small cell lung cancer. Cancer Res 2006; 66: 7854-7858.
    • (2006) Cancer Res , vol.66 , pp. 7854-7858
    • Inukai, M.1    Toyooka, S.2    Ito, S.3
  • 20
    • 47949114668 scopus 로고    scopus 로고
    • Detection of mutations in EGFR in circulating lung-cancer cells
    • Maheswaran S, Sequist LV, Nagrath S et al. Detection of mutations in EGFR in circulating lung-cancer cells. N Engl J Med 2008; 359: 366-377.
    • (2008) N Engl J Med , vol.359 , pp. 366-377
    • Maheswaran, S.1    Sequist, L.V.2    Nagrath, S.3
  • 21
    • 77953541527 scopus 로고    scopus 로고
    • Erlotinib as maintenance treatment in advanced non-small-cell lung cancer: a multicentre, randomised placebocontrolled phase 3 study
    • Cappuzzo F, Coudert B, Wierzbicki R et al. Erlotinib as maintenance treatment in advanced non-small-cell lung cancer: a multicentre, randomised placebocontrolled phase 3 study. Lancet Oncol 2010; 11: 521-529.
    • (2010) Lancet Oncol , vol.11 , pp. 521-529
    • Cappuzzo, F.1    Coudert, B.2    Wierzbicki, R.3
  • 22
    • 33845214742 scopus 로고    scopus 로고
    • Monitoring standards for molecular genetic testing in the United Kingdom, the Netherlands, and Ireland
    • Ramsden SC, Deans Z, Robinson DO et al. Monitoring standards for molecular genetic testing in the United Kingdom, the Netherlands, and Ireland. Genet Test 2006; 10: 147-156.
    • (2006) Genet Test , vol.10 , pp. 147-156
    • Ramsden, S.C.1    Deans, Z.2    Robinson, D.O.3
  • 23
    • 70349336416 scopus 로고    scopus 로고
    • Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK
    • Shaw AT, Yeap BY, Mino-Kenudson M et al. Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK. J Clin Oncol 2009; 27: 4247-4253.
    • (2009) J Clin Oncol , vol.27 , pp. 4247-4253
    • Shaw, A.T.1    Yeap, B.Y.2    Mino-Kenudson, M.3
  • 24
    • 78349237453 scopus 로고    scopus 로고
    • Optimizing the detection of lung cancer patients harboring anaplastic lymphoma kinase (ALK) gene rearrangements potentially suitable for ALK inhibitor treatment
    • Camidge DR, Kono SA, Flacco A et al. Optimizing the detection of lung cancer patients harboring anaplastic lymphoma kinase (ALK) gene rearrangements potentially suitable for ALK inhibitor treatment. Clin Cancer Res 2010; 16: 5581-5590.
    • (2010) Clin Cancer Res , vol.16 , pp. 5581-5590
    • Camidge, D.R.1    Kono, S.A.2    Flacco, A.3
  • 25
    • 69349083935 scopus 로고    scopus 로고
    • Unique clinicopathologic features characterize ALK-rearranged lung adenocarcinoma in the western population
    • Rodig SJ, Mino-Kenudson M, Dacic S et al. Unique clinicopathologic features characterize ALK-rearranged lung adenocarcinoma in the western population. Clin Cancer Res 2009; 15: 5216-5223.
    • (2009) Clin Cancer Res , vol.15 , pp. 5216-5223
    • Rodig, S.J.1    Mino-Kenudson, M.2    Dacic, S.3
  • 26
    • 78049425319 scopus 로고    scopus 로고
    • Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer
    • Kwak EL, Bang YJ, Camidge DR et al. Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer. N Engl J Med 2010; 363: 1693-1703.
    • (2010) N Engl J Med , vol.363 , pp. 1693-1703
    • Kwak, E.L.1    Bang, Y.J.2    Camidge, D.R.3
  • 27
    • 52049099853 scopus 로고    scopus 로고
    • PIK3CA mutations and copy number gains in human lung cancers
    • Yamamoto H, Shigematsu H, Nomura M et al. PIK3CA mutations and copy number gains in human lung cancers. Cancer Res 2008; 68: 6913-6921.
    • (2008) Cancer Res , vol.68 , pp. 6913-6921
    • Yamamoto, H.1    Shigematsu, H.2    Nomura, M.3
  • 28
    • 20144386787 scopus 로고    scopus 로고
    • Somatic mutations of the HER2 kinase domain in lung adenocarcinomas
    • Shigematsu H, Takahashi T, Nomura M et al. Somatic mutations of the HER2 kinase domain in lung adenocarcinomas. Cancer Res 2005; 65: 1642-1646.
    • (2005) Cancer Res , vol.65 , pp. 1642-1646
    • Shigematsu, H.1    Takahashi, T.2    Nomura, M.3
  • 29
    • 34250837538 scopus 로고    scopus 로고
    • Patterns of EGFR, HER2, TP53, and KRAS mutations of p14arf expression in non-small cell lung cancers in relation to smoking history
    • Mounawar M, Mukeria A, Le Calvez F et al. Patterns of EGFR, HER2, TP53, and KRAS mutations of p14arf expression in non-small cell lung cancers in relation to smoking history. Cancer Res 2007; 67: 5667-5672.
    • (2007) Cancer Res , vol.67 , pp. 5667-5672
    • Mounawar, M.1    Mukeria, A.2    Le Calvez, F.3
  • 30
    • 68049088934 scopus 로고    scopus 로고
    • EGFR/KRAS/BRAF mutations in primary lung adenocarcinomas and corresponding locoregional lymph node metastases
    • Schmid K, Oehl N, Wrba F et al. EGFR/KRAS/BRAF mutations in primary lung adenocarcinomas and corresponding locoregional lymph node metastases. Clin Cancer Res 2009; 15: 4554-4560.
    • (2009) Clin Cancer Res , vol.15 , pp. 4554-4560
    • Schmid, K.1    Oehl, N.2    Wrba, F.3
  • 31
    • 34447573875 scopus 로고    scopus 로고
    • Customizing cisplatin based on quantitative excision repair cross-complementing 1 mRNA expression: a phase III trial in nonsmall-cell lung cancer
    • Cobo M, Isla D, Massuti B et al. Customizing cisplatin based on quantitative excision repair cross-complementing 1 mRNA expression: a phase III trial in nonsmall-cell lung cancer. J Clin Oncol 2007; 25: 2747-2754.
    • (2007) J Clin Oncol , vol.25 , pp. 2747-2754
    • Cobo, M.1    Isla, D.2    Massuti, B.3
  • 32
    • 12444288071 scopus 로고    scopus 로고
    • Transcripts in pretreatment biopsies from a three-arm randomized trial in metastatic non-small-cell lung cancer
    • Rosell R, Scagliotti G, Danenberg KD et al. Transcripts in pretreatment biopsies from a three-arm randomized trial in metastatic non-small-cell lung cancer. Oncogene 2003; 22: 3548-3553.
    • (2003) Oncogene , vol.22 , pp. 3548-3553
    • Rosell, R.1    Scagliotti, G.2    Danenberg, K.D.3
  • 33
    • 33845361135 scopus 로고    scopus 로고
    • ERCC1 and RRM1 gene expressions but not EGFR are predictive of shorter survival in advanced non-small-cell lung cancer treated with cisplatin and gemcitabine
    • Ceppi P, Volante M, Novello S et al. ERCC1 and RRM1 gene expressions but not EGFR are predictive of shorter survival in advanced non-small-cell lung cancer treated with cisplatin and gemcitabine. Ann Oncol 2006; 17: 1818-1825.
    • (2006) Ann Oncol , vol.17 , pp. 1818-1825
    • Ceppi, P.1    Volante, M.2    Novello, S.3
  • 34
    • 0141954010 scopus 로고    scopus 로고
    • BRCA1 functions as a differential modulator of chemotherapy-induced apoptosis
    • Quinn JE, Kennedy RD, Mullan PB et al. BRCA1 functions as a differential modulator of chemotherapy-induced apoptosis. Cancer Res 2003; 63: 6221-6228.
    • (2003) Cancer Res , vol.63 , pp. 6221-6228
    • Quinn, J.E.1    Kennedy, R.D.2    Mullan, P.B.3
  • 35
    • 19544379515 scopus 로고    scopus 로고
    • BRCA1 mRNA expression levels as an indicator of chemoresistance in lung cancer
    • Taron M, Rosell R, Felip E et al. BRCA1 mRNA expression levels as an indicator of chemoresistance in lung cancer. Hum Mol Genet 2004; 13: 2443-2449.
    • (2004) Hum Mol Genet , vol.13 , pp. 2443-2449
    • Taron, M.1    Rosell, R.2    Felip, E.3
  • 36
    • 58149177773 scopus 로고    scopus 로고
    • Tumor BRCA1,RRM1 and RRM2 mRNA expression levels and clinical response to first-line gemcitabine plus docetaxel in non-small-cell lung cancer patients
    • Boukovinas I, Papadaki C, Mendez P et al. Tumor BRCA1, RRM1 and RRM2 mRNA expression levels and clinical response to first-line gemcitabine plus docetaxel in non-small-cell lung cancer patients. PLoS ONE 2008; 3: e3695.
    • (2008) PLoS ONE , vol.3
    • Boukovinas, I.1    Papadaki, C.2    Mendez, P.3
  • 37
    • 67649431893 scopus 로고    scopus 로고
    • Customized treatment in non-small-cell lung cancer based on EGFR mutations and BRCA1 mRNA expression
    • Rosell R, Perez-Roca L, Sanchez JJ et al. Customized treatment in non-small-cell lung cancer based on EGFR mutations and BRCA1 mRNA expression. PLoS ONE 2009; 4: e5133.
    • (2009) PLoS ONE , vol.4
    • Rosell, R.1    Perez-Roca, L.2    Sanchez, J.J.3
  • 39
    • 62549123345 scopus 로고    scopus 로고
    • Long-term survival expectations of cancer patients in Europe in 2000-2002
    • Brenner H, Francisci S, de Angelis R et al. Long-term survival expectations of cancer patients in Europe in 2000-2002. Eur J Cancer 2009; 45: 1028-1041.
    • (2009) Eur J Cancer , vol.45 , pp. 1028-1041
    • Brenner, H.1    Francisci, S.2    de Angelis, R.3
  • 40
    • 53749097825 scopus 로고    scopus 로고
    • SCLC., Meta-Analyses Collaborative, Group., Chemotherapy in addition to supportive care improves survival in advanced non small cell lung cancer: a systematic review and meta-analysis of individual patient data of 16 controlled clinical, trials
    • SCLC Meta-Analyses Collaborative Group. Chemotherapy in addition to supportive care improves survival in advanced non small cell lung cancer: a systematic review and meta-analysis of individual patient data of 16 controlled clinical trials. J Clin Oncol 2008; 26: 4617-4625.
    • (2008) J. Clin Oncol , vol.26 , pp. 4617-4625
  • 41
    • 0006453669 scopus 로고    scopus 로고
    • Elderly Lung Cancer Vinorelbine Italian Study (ELVIS), Group., Effects of vinorelbine on quality of life and survival of elderly patients with advanced non-small-cell lung, cancer
    • Elderly Lung Cancer Vinorelbine Italian Study (ELVIS) Group. Effects of vinorelbine on quality of life and survival of elderly patients with advanced non-small-cell lung cancer. J Natl Cancer Inst 1999; 91: 66-72.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 66-72
  • 42
    • 59149092945 scopus 로고    scopus 로고
    • Phase III study of immediate compared with delayed docetaxel after front-line therapy with gemcitabine plus carboplatin in advanced non-small-cell lung cancer
    • Fidias PM, Dakhil SR, Lyss AP et al. Phase III study of immediate compared with delayed docetaxel after front-line therapy with gemcitabine plus carboplatin in advanced non-small-cell lung cancer. J Clin Oncol 2009; 27: 591-598.
    • (2009) J Clin Oncol , vol.27 , pp. 591-598
    • Fidias, P.M.1    Dakhil, S.R.2    Lyss, A.P.3
  • 43
    • 19444365516 scopus 로고    scopus 로고
    • Platinum-based versus non-platinumbased chemotherapy in advanced non-small-cell lung cancer: a meta-analysis of the published literature
    • D'Addario G, Pintilie M, Leighl MB et al. Platinum-based versus non-platinumbased chemotherapy in advanced non-small-cell lung cancer: a meta-analysis of the published literature. J Clin Oncol 2005; 23: 2926-2936.
    • (2005) J Clin Oncol , vol.23 , pp. 2926-2936
    • D'Addario, G.1    Pintilie, M.2    Leighl, M.B.3
  • 44
    • 33144474858 scopus 로고    scopus 로고
    • Should chemotherapy combination for advanced non-small cell lung cancer be platinum-based? A meta-analysis of phase III randomized trials
    • Pujol JL, Barlesi F, Daures JP. Should chemotherapy combination for advanced non-small cell lung cancer be platinum-based? A meta-analysis of phase III randomized trials. Lung Cancer 2006; 51: 335-345.
    • (2006) Lung Cancer , vol.51 , pp. 335-345
    • Pujol, J.L.1    Barlesi, F.2    Daures, J.P.3
  • 45
    • 5444235920 scopus 로고    scopus 로고
    • Meta-analysis of randomized clinical trials comparing cisplatin to carboplatin in patients with advanced non small cell lung cancer
    • Hotta K, Matsuo K, Ueoka H et al. Meta-analysis of randomized clinical trials comparing cisplatin to carboplatin in patients with advanced non small cell lung cancer. J Clin Oncol 2004; 22: 3852-3859.
    • (2004) J Clin Oncol , vol.22 , pp. 3852-3859
    • Hotta, K.1    Matsuo, K.2    Ueoka, H.3
  • 46
    • 34347379142 scopus 로고    scopus 로고
    • Cisplatin- versus carboplatin-based chemotherapy in first-line treatment of advanced non-small-cell lung cancer: an individual patient data meta-analysis
    • Ardizzoni A, Boni L, Tiseo M et al. Cisplatin- versus carboplatin-based chemotherapy in first-line treatment of advanced non-small-cell lung cancer: an individual patient data meta-analysis. J Natl Cancer Inst 2007; 99: 847-857.
    • (2007) J Natl Cancer Inst , vol.99 , pp. 847-857
    • Ardizzoni, A.1    Boni, L.2    Tiseo, M.3
  • 47
    • 11144357752 scopus 로고    scopus 로고
    • Treatment of advanced non-smallcell lung cancer patients with ECOG performance status 2: results of an European Experts Panel
    • Gridelli C, Ardizzoni A, Le Chavalier T et al. Treatment of advanced non-smallcell lung cancer patients with ECOG performance status 2: results of an European Experts Panel. Ann Oncol 2004; 15: 419-426.
    • (2004) Ann Oncol , vol.15 , pp. 419-426
    • Gridelli, C.1    Ardizzoni, A.2    Le Chavalier, T.3
  • 48
    • 68549094542 scopus 로고    scopus 로고
    • Single-agent versus combination chemotherapy in patients with advanced non-small cell lung cancer and a performance status of 2: prognostic factors and treatment selection based on two large randomized clinical trials
    • Lilenbaum R, Villaflor VM, Langer C et al. Single-agent versus combination chemotherapy in patients with advanced non-small cell lung cancer and a performance status of 2: prognostic factors and treatment selection based on two large randomized clinical trials. J Thorac Oncol 2009; 4: 869-874.
    • (2009) J Thorac Oncol , vol.4 , pp. 869-874
    • Lilenbaum, R.1    Villaflor, V.M.2    Langer, C.3
  • 49
    • 44649193032 scopus 로고    scopus 로고
    • Phase III trial comparing paclitaxel poliglumex (CT-2103, PPX) in combination with carboplatin versus standard paclitaxel and carboplatin in the treatment of PS 2 patients with chemotherapynai{dotless} ̈ve advanced non-small cell lung cancer
    • Langer CJ, O'Byrne KJ, Socinski MA et al. Phase III trial comparing paclitaxel poliglumex (CT-2103, PPX) in combination with carboplatin versus standard paclitaxel and carboplatin in the treatment of PS 2 patients with chemotherapynai{dotless} ̈ve advanced non-small cell lung cancer. J Thorac Oncol 2008; 3: 623-630.
    • (2008) J Thorac Oncol , vol.3 , pp. 623-630
    • Langer, C.J.1    O'Byrne, K.J.2    Socinski, M.A.3
  • 50
    • 0037420202 scopus 로고    scopus 로고
    • Chemotherapy for elderly patients with advanced non-small-cell lung cancer: the Multicenter Italian Lung Cancer in the Elderly Study (MILES) phase III randomized trial
    • Gridelli C, Perrone F, Gallo C et al. Chemotherapy for elderly patients with advanced non-small-cell lung cancer: the Multicenter Italian Lung Cancer in the Elderly Study (MILES) phase III randomized trial. J Natl Cancer Inst 2003; 95: 362-372.
    • (2003) J Natl Cancer Inst , vol.95 , pp. 362-372
    • Gridelli, C.1    Perrone, F.2    Gallo, C.3
  • 51
    • 0037028750 scopus 로고    scopus 로고
    • Cisplatin-based therapy for elderly patients with advanced non-small-cell lung cancer: implications of Eastern Cooperative Oncology Group 5592, a randomized trial
    • Langer CJ, Manola J, Bernardo P et al. Cisplatin-based therapy for elderly patients with advanced non-small-cell lung cancer: implications of Eastern Cooperative Oncology Group 5592, a randomized trial. J Natl Cancer Inst 2002; 94: 173-181.
    • (2002) J Natl Cancer Inst , vol.94 , pp. 173-181
    • Langer, C.J.1    Manola, J.2    Bernardo, P.3
  • 52
    • 77956832754 scopus 로고    scopus 로고
    • Weekly paclitaxel combined with monthly carboplatin versus single-agent therapy in patients aged 70 to 89, IFCT-0501 randomized phase III study in advanced non-small cell lung cancer (NSCLC)
    • (Abstr 2)
    • Quoix EA, Oster J, Pichon E et al. Weekly paclitaxel combined with monthly carboplatin versus single-agent therapy in patients aged 70 to 89: IFCT-0501 randomized phase III study in advanced non-small cell lung cancer (NSCLC). J Clin Oncol 2010; 28(15s): 5s (Abstr 2).
    • (2010) J Clin Oncol , vol.28 , Issue.15 S
    • Quoix, E.A.1    Oster, J.2    Pichon, E.3
  • 53
    • 0037050352 scopus 로고    scopus 로고
    • Comparison of four chemotherapy regimens for advanced non small cell lung cancer
    • Schiller J, Harrington D, Belani CP et al. Comparison of four chemotherapy regimens for advanced non small cell lung cancer. N Engl J Med 2002; 346: 92-98.
    • (2002) N Engl J Med , vol.346 , pp. 92-98
    • Schiller, J.1    Harrington, D.2    Belani, C.P.3
  • 54
    • 0042413836 scopus 로고    scopus 로고
    • Randomized, multinational, phase III study of docetaxel plus platinum combinations versus vinorelbine plus cisplatin in advanced non small cell lung cancer: the TAX 326 study group
    • Fossella F, Pereira JR, von Pawel J et al. Randomized, multinational, phase III study of docetaxel plus platinum combinations versus vinorelbine plus cisplatin in advanced non small cell lung cancer: the TAX 326 study group. J Clin Oncol 2003; 21: 3016-3024.
    • (2003) J Clin Oncol , vol.21 , pp. 3016-3024
    • Fossella, F.1    Pereira, J.R.2    von Pawel, J.3
  • 55
    • 0036843105 scopus 로고    scopus 로고
    • Phase III randomized trial comparing three platinum-based doublets in advanced non small cell lung
    • Scagliotti G, de Marinis F, Rinaldi M et al. Phase III randomized trial comparing three platinum-based doublets in advanced non small cell lung. J Clin Oncol 2002; 20: 4285-4291.
    • (2002) J Clin Oncol , vol.20 , pp. 4285-4291
    • Scagliotti, G.1    de Marinis, F.2    Rinaldi, M.3
  • 56
    • 49049089802 scopus 로고    scopus 로고
    • Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small cell lung cancer
    • Scagliotti G, Parikh P, von Pawel J et al. Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small cell lung cancer. J Clin Oncol 2008; 26: 3543-3551.
    • (2008) J Clin Oncol , vol.26 , pp. 3543-3551
    • Scagliotti, G.1    Parikh, P.2    von Pawel, J.3
  • 57
    • 0035281498 scopus 로고    scopus 로고
    • Duration of chemotherapy in advanced non-small-cell lung cancer: a randomized trial of three versus six courses of mitomycin, vinblastine, and cisplatin
    • Smith IE, O'Brien ME, Talbot DC et al. Duration of chemotherapy in advanced non-small-cell lung cancer: a randomized trial of three versus six courses of mitomycin, vinblastine, and cisplatin. J Clin Oncol 2001; 19: 1336-1343.
    • (2001) J Clin Oncol , vol.19 , pp. 1336-1343
    • Smith, I.E.1    O'Brien, M.E.2    Talbot, D.C.3
  • 58
    • 33750207905 scopus 로고    scopus 로고
    • Palliative chemotherapy beyond three courses conveys no survival or consistent quality-of-life benefits in advanced non-small-cell lung cancer
    • von Plessen C, Bergman B, Andresen O et al. Palliative chemotherapy beyond three courses conveys no survival or consistent quality-of-life benefits in advanced non-small-cell lung cancer. Br J Cancer 2006; 95: 966-973.
    • (2006) Br J Cancer , vol.95 , pp. 966-973
    • von Plessen, C.1    Bergman, B.2    Andresen, O.3
  • 59
    • 63849290363 scopus 로고    scopus 로고
    • Potential treatment options after first-line chemotherapy for advanced non small cell lung cancer: maintenance treatment or early second-line?
    • Gridelli C, Maione P, Rossi A et al. Potential treatment options after first-line chemotherapy for advanced non small cell lung cancer: maintenance treatment or early second-line? Oncologist 2009; 14: 137-147.
    • (2009) Oncologist , vol.14 , pp. 137-147
    • Gridelli, C.1    Maione, P.2    Rossi, A.3
  • 60
    • 70350225538 scopus 로고    scopus 로고
    • Maintenance pemetrexed plus best supportive care versus placebo plus best supportive care for non-small-cell lung cancer: a randomised, double-blind, phase 3 study
    • Ciuleanu T, Brodowicz T, Zielinski C et al. Maintenance pemetrexed plus best supportive care versus placebo plus best supportive care for non-small-cell lung cancer: a randomised, double-blind, phase 3 study. Lancet 2009; 374: 1432-1440.
    • (2009) Lancet , vol.374 , pp. 1432-1440
    • Ciuleanu, T.1    Brodowicz, T.2    Zielinski, C.3
  • 61
    • 33845490014 scopus 로고    scopus 로고
    • Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
    • Sandler A, Gray R, Perry MC et al. Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N Engl J Med 2006; 355: 2542-2550.
    • (2006) N Engl J Med , vol.355 , pp. 2542-2550
    • Sandler, A.1    Gray, R.2    Perry, M.C.3
  • 62
    • 77951473661 scopus 로고    scopus 로고
    • Overall survival with cisplatingemcitabine and bevacizumab or placebo as first-line therapy for nonsquamous non-small-cell lung cancer: results from a randomised phase III trial (AVAiL)
    • Reck M, von Pawel J, Zatloukal P et al. Overall survival with cisplatingemcitabine and bevacizumab or placebo as first-line therapy for nonsquamous non-small-cell lung cancer: results from a randomised phase III trial (AVAiL). Ann Oncol 2010; 21: 1804-1809.
    • (2010) Ann Oncol , vol.21 , pp. 1804-1809
    • Reck, M.1    von Pawel, J.2    Zatloukal, P.3
  • 63
    • 65349116059 scopus 로고    scopus 로고
    • Cetuximab plus chemotherapy in patients with advanced non-small-cell lung cancer (FLEX): an open-label randomised phase III trial
    • Pirker R, Pereira JR, Szczesna A et al. Cetuximab plus chemotherapy in patients with advanced non-small-cell lung cancer (FLEX): an open-label randomised phase III trial. Lancet 2009; 373: 1525-1531.
    • (2009) Lancet , vol.373 , pp. 1525-1531
    • Pirker, R.1    Pereira, J.R.2    Szczesna, A.3
  • 64
    • 77949891126 scopus 로고    scopus 로고
    • Cetuximab and first-line taxane/carboplatin chemotherapy in advanced non-small-cell lung cancer: results of the randomized multicenter phase III trial BMS099
    • Lynch TJ, Patel T, Dreisbach L et al. Cetuximab and first-line taxane/carboplatin chemotherapy in advanced non-small-cell lung cancer: results of the randomized multicenter phase III trial BMS099. J Clin Oncol 2010; 28: 911-917.
    • (2010) J Clin Oncol , vol.28 , pp. 911-917
    • Lynch, T.J.1    Patel, T.2    Dreisbach, L.3
  • 65
    • 74049104196 scopus 로고    scopus 로고
    • Cetuximab plus platinum-based chemotherapy as 1st-line treatment in patients with non-small-cell lung cancer: a meta-analysis of randomized phase II/III trials
    • Thatcher N, Lynch TJ, Butts CA et al. Cetuximab plus platinum-based chemotherapy as 1st-line treatment in patients with non-small-cell lung cancer: a meta-analysis of randomized phase II/III trials. J Thorac Oncol 2009; 4 (Suppl 1): S297.
    • (2009) J Thorac Oncol , vol.4 , Issue.SUPPL. 1
    • Thatcher, N.1    Lynch, T.J.2    Butts, C.A.3
  • 66
    • 84883436677 scopus 로고    scopus 로고
    • First-cycle rash as a clinical marker in patients with advanced non-small cell lung cancer receiving first-line chemotherapy plus cetuximab: efficacy by histology
    • O'Byrne KJ, von Pawel J, Vynnychenko I et al. First-cycle rash as a clinical marker in patients with advanced non-small cell lung cancer receiving first-line chemotherapy plus cetuximab: efficacy by histology. J Clin Oncol 2010; 28 (Suppl 1): 7s.
    • (2010) J Clin Oncol , vol.28 , Issue.SUPPL. 1
    • O'Byrne, K.J.1    von Pawel, J.2    Vynnychenko, I.3
  • 67
    • 79954606282 scopus 로고    scopus 로고
    • on behalf of the OPTIMAL investigators. Efficacy results from the randomised phase III OPTIMAL (CTONG 0802) study comparing first-line erlotinib versus carboplatin plus gemcitabine, in chinese advanced nonsmall-cell lung cancer patients with EGFR activating mutations
    • (Abstr LBA13)
    • Zhou C, Wung YI, Chen G et al. on behalf of the OPTIMAL investigators. Efficacy results from the randomised phase III OPTIMAL (CTONG 0802) study comparing first-line erlotinib versus carboplatin plus gemcitabine, in chinese advanced nonsmall-cell lung cancer patients with EGFR activating mutations. Ann Oncol 2010; 21 (Suppl 8): (Abstr LBA13).
    • (2010) Ann Oncol , vol.21 , Issue.SUPPL. 8
    • Zhou, C.1    Wung, Y.I.2    Chen, G.3
  • 68
    • 69249196041 scopus 로고    scopus 로고
    • The role of chemotherapy in the treatment of patients with brain metastases from solid tumors
    • Walbert T, Gilbert MR. The role of chemotherapy in the treatment of patients with brain metastases from solid tumors. Int J Clin Oncol 2009; 14: 299-306.
    • (2009) Int J Clin Oncol , vol.14 , pp. 299-306
    • Walbert, T.1    Gilbert, M.R.2
  • 69
    • 0035137984 scopus 로고    scopus 로고
    • Results of a phase III study of early versus delayed whole brain radiotherapy with concurrent cisplatin and vinorelbine combination in inoperable brain metastasis of non-small-cell lung cancer: Groupe Francxais de Pneumo-Cancé rologie (GFPC) Protocol 95-1
    • Robinet G, Thomas P, Breton JL et al. Results of a phase III study of early versus delayed whole brain radiotherapy with concurrent cisplatin and vinorelbine combination in inoperable brain metastasis of non-small-cell lung cancer: Groupe Francxais de Pneumo-Cancé rologie (GFPC) Protocol 95-1. Ann Oncol 2001; 12: 59-67.
    • (2001) Ann Oncol , vol.12 , pp. 59-67
    • Robinet, G.1    Thomas, P.2    Breton, J.L.3
  • 70
    • 22044445517 scopus 로고    scopus 로고
    • Erlotinib in previously treated non-small-cell lung cancer
    • Shepherd FA, Rodrigues Pereira J, Ciuleanu T et al. Erlotinib in previously treated non-small-cell lung cancer. N Engl J Med 2005; 353: 123-132.
    • (2005) N Engl J Med , vol.353 , pp. 123-132
    • Shepherd, F.A.1    Rodrigues Pereira, J.2    Ciuleanu, T.3
  • 71
    • 2442661845 scopus 로고    scopus 로고
    • Randomized phase III trial of pemetrexed versus docetaxel in patients with non-small-cell lung cancer previously treated with chemotherapy
    • Hanna N, Shepherd FA, Fosella FV et al. Randomized phase III trial of pemetrexed versus docetaxel in patients with non-small-cell lung cancer previously treated with chemotherapy. J Clin Oncol 2004; 9: 1589-1597.
    • (2004) J Clin Oncol , vol.9 , pp. 1589-1597
    • Hanna, N.1    Shepherd, F.A.2    Fosella, F.V.3
  • 72
    • 0034069620 scopus 로고    scopus 로고
    • Prospective randomized trial of docetaxel versus best supportive care in patients with non-small-cell lung cancer previously treated with platinum-based chemotherapy
    • Shepherd FA, Dancey J, Ramlau R et al. Prospective randomized trial of docetaxel versus best supportive care in patients with non-small-cell lung cancer previously treated with platinum-based chemotherapy. J Clin Oncol 2000; 18: 2095-2103.
    • (2000) J Clin Oncol , vol.18 , pp. 2095-2103
    • Shepherd, F.A.1    Dancey, J.2    Ramlau, R.3
  • 73
    • 64649091718 scopus 로고    scopus 로고
    • Meta-analysis of single agent chemotherapy compared with combination therapy as second line treatment of advanced lung cancer
    • Di Maio M, Chiodini P, Georgoulias V et al. Meta-analysis of single agent chemotherapy compared with combination therapy as second line treatment of advanced lung cancer. J Clin Oncol 2009; 27: 1836-1843.
    • (2009) J Clin Oncol , vol.27 , pp. 1836-1843
    • Di Maio, M.1    Chiodini, P.2    Georgoulias, V.3
  • 74
    • 0037214171 scopus 로고    scopus 로고
    • A retrospective analysis of the outcome of patients who have received two prior chemotherapy regimens including platinum and docetaxel for recurrent non-small-cell lung cancer
    • Massarelli E, Andre L, Liu DD et al. A retrospective analysis of the outcome of patients who have received two prior chemotherapy regimens including platinum and docetaxel for recurrent non-small-cell lung cancer. Lung Cancer 2003; 39: 55-61.
    • (2003) Lung Cancer , vol.39 , pp. 55-61
    • Massarelli, E.1    Andre, L.2    Liu, D.D.3
  • 75
    • 4944226682 scopus 로고    scopus 로고
    • Effect of gefitinib ('Iressa', ZD1839) on brain metastases in patients with advanced non-small-cell lung cancer
    • Hotta H, Kiura K, Ueoka M et al. Effect of gefitinib ('Iressa', ZD1839) on brain metastases in patients with advanced non-small-cell lung cancer. Lung Cancer 2004; 46: 255-256.
    • (2004) Lung Cancer , vol.46 , pp. 255-256
    • Hotta, H.1    Kiura, K.2    Ueoka, M.3
  • 76
    • 77649322365 scopus 로고    scopus 로고
    • Second-line therapy for elderly patients with non-small cell lung cancer who failed previous chemotherapy is as effective as for younger patients
    • Wu CH, Fan WC, Chen YM et al. Second-line therapy for elderly patients with non-small cell lung cancer who failed previous chemotherapy is as effective as for younger patients. J Thorac Oncol 2010; 5: 376-379.
    • (2010) J Thorac Oncol , vol.5 , pp. 376-379
    • Wu, C.H.1    Fan, W.C.2    Chen, Y.M.3
  • 77
    • 33749077728 scopus 로고    scopus 로고
    • Elderly patients benefit from second-line cytotoxic chemotherapy: a subset analysis of a randomized phase III trial of pemetrexed compared with docetaxel in patients with previously treated advanced non-small-cell lung cancer
    • Weis GJ, Langer C, Rosell R et al. Elderly patients benefit from second-line cytotoxic chemotherapy: a subset analysis of a randomized phase III trial of pemetrexed compared with docetaxel in patients with previously treated advanced non-small-cell lung cancer. J Clin Oncol 2006; 24: 4405-4411.
    • (2006) J Clin Oncol , vol.24 , pp. 4405-4411
    • Weis, G.J.1    Langer, C.2    Rosell, R.3
  • 78
    • 56249109644 scopus 로고    scopus 로고
    • Gefitinib versus docetaxel in previously treated patients with non-small-cell-lung-cancer (INTEREST): a randomized phase III trial
    • Kim SE, Hirch V, Mok T et al. Gefitinib versus docetaxel in previously treated patients with non-small-cell-lung-cancer (INTEREST): a randomized phase III trial. Lancet 2008; 372: 1809-1818.
    • (2008) Lancet , vol.372 , pp. 1809-1818
    • Kim, S.E.1    Hirch, V.2    Mok, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.