-
1
-
-
33845235459
-
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
-
Bartkova, J., Rezaei, N., Liontos, M., Karakaidos, P., Kletsas, D., Issaeva, N., Vassiliou, L.V., Kolettas, E., Niforou, K., Zoumpourlis, V.C., et al. (2006). Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints. Nature 444, 633-637.
-
(2006)
Nature
, vol.444
, pp. 633-637
-
-
Bartkova, J.1
Rezaei, N.2
Liontos, M.3
Karakaidos, P.4
Kletsas, D.5
Issaeva, N.6
Vassiliou, L.V.7
Kolettas, E.8
Niforou, K.9
Zoumpourlis, V.C.10
-
2
-
-
84859255818
-
The DNA translocase activity of FANCM protects stalled replication forks
-
Blackford, A.N., Schwab, R.A., Nieminuszczy, J., Deans, A.J., West, S.C., and Niedzwiedz, W. (2012). The DNA translocase activity of FANCM protects stalled replication forks. Human molecular genetics 21, 2005-2016.
-
(2012)
Human Molecular Genetics
, vol.21
, pp. 2005-2016
-
-
Blackford, A.N.1
Schwab, R.A.2
Nieminuszczy, J.3
Deans, A.J.4
West, S.C.5
Niedzwiedz, W.6
-
3
-
-
84877584276
-
Mutations in ERCC4, encoding the DNA-repair endonuclease XPF, cause Fanconi anemia
-
Bogliolo, M., Schuster, B., Stoepker, C., Derkunt, B., Su, Y., Raams, A., Trujillo, J.P., Minguillon, J., Ramirez, M.J., Pujol, R., et al. 2013. Mutations in ERCC4, encoding the DNA-repair endonuclease XPF, cause Fanconi anemia. American journal of human genetics 92, 800-806.
-
(2013)
American Journal of Human Genetics
, vol.92
, pp. 800-806
-
-
Bogliolo, M.1
Schuster, B.2
Stoepker, C.3
Derkunt, B.4
Su, Y.5
Raams, A.6
Trujillo, J.P.7
Minguillon, J.8
Ramirez, M.J.9
Pujol, R.10
-
4
-
-
17244375049
-
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
-
Bryant, H.E., Schultz, N., Thomas, H.D., Parker, K.M., Flower, D., Lopez, E., Kyle, S., Meuth, M., Curtin, N.J., and Helleday, T. (2005). Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase. Nature 434, 913-917.
-
(2005)
Nature
, vol.434
, pp. 913-917
-
-
Bryant, H.E.1
Schultz, N.2
Thomas, H.D.3
Parker, K.M.4
Flower, D.5
Lopez, E.6
Kyle, S.7
Meuth, M.8
Curtin, N.J.9
Helleday, T.10
-
5
-
-
84942039168
-
Regulation of the Rev1-pol zeta complex during bypass of a DNA interstrand cross-link
-
[Epub ahead of print]
-
Budzowska, M., Graham, T.G., Sobeck, A., Waga, S., and Walter, J.C. (2015). Regulation of the Rev1-pol zeta complex during bypass of a DNA interstrand cross-link. EMBO J. pii: e201490878. [Epub ahead of print]
-
(2015)
EMBO J
, pp. 201490878
-
-
Budzowska, M.1
Graham, T.G.2
Sobeck, A.3
Waga, S.4
Walter, J.C.5
-
6
-
-
84862776819
-
BRCA1 functions independently of homologous recombination in DNA interstrand crosslink repair
-
Bunting, S.F., Callen, E., Kozak, M.L., Kim, J.M., Wong, N., Lopez- Contreras, A.J., Ludwig, T., Baer, R., Faryabi, R.B., Malhowski, A., et al. (2012). BRCA1 functions independently of homologous recombination in DNA interstrand crosslink repair. Mol. Cell 46, 125-135.
-
(2012)
Mol. Cell
, vol.46
, pp. 125-135
-
-
Bunting, S.F.1
Callen, E.2
Kozak, M.L.3
Kim, J.M.4
Wong, N.5
Lopez- Contreras, A.J.6
Ludwig, T.7
Baer, R.8
Faryabi, R.B.9
Malhowski, A.10
-
7
-
-
84923082911
-
Homologous- recombination-deficient tumours are dependent on Poltheta- mediated repair
-
Ceccaldi, R., Liu, J.C., Amunugama, R., Hajdu, I., Primack, B., Petalcorin, M.I., O’Connor, K.W., Konstantinopoulos, P.A., Elledge, S.J., Boulton, S.J., et al. (2015). Homologous- recombination-deficient tumours are dependent on Poltheta- mediated repair. Nature 518, 258-262.
-
(2015)
Nature
, vol.518
, pp. 258-262
-
-
Ceccaldi, R.1
Liu, J.C.2
Amunugama, R.3
Hajdu, I.4
Primack, B.5
Petalcorin, M.I.6
O’Connor, K.W.7
Konstantinopoulos, P.A.8
Elledge, S.J.9
Boulton, S.J.10
-
8
-
-
58249109379
-
DNA damage tolerance: when it’s OK to make mistakes
-
Chang, D.J., and Cimprich, K.A. (2009). DNA damage tolerance: when it’s OK to make mistakes. Nat. Chem. Biol. 5, 82-90.
-
(2009)
Nat. Chem. Biol
, vol.5
, pp. 82-90
-
-
Chang, D.J.1
Cimprich, K.A.2
-
9
-
-
65449142073
-
CHK1 inhibition as a strategy for targeting Fanconi Anemia (FA) DNA repair pathway deficient tumors
-
Chen, C.C., Kennedy, R.D., Sidi, S., Look, A.T., and D’Andrea, A. (2009). CHK1 inhibition as a strategy for targeting Fanconi Anemia (FA) DNA repair pathway deficient tumors. Mol. Cancer 8, 24.
-
(2009)
Mol. Cancer
, vol.8
, pp. 24
-
-
Chen, C.C.1
Kennedy, R.D.2
Sidi, S.3
Look, A.T.4
D’Andrea, A.5
-
10
-
-
18244405819
-
Human Mus81-associated endonuclease cleaves Holliday junctions in vitro
-
Chen, X.B., Melchionna, R., Denis, C.M., Gaillard, P.H., Blasina, A., Van de Weyer, I., Boddy, M.N., Russell, P., Vialard, J., and McGowan, C.H. (2001). Human Mus81-associated endonuclease cleaves Holliday junctions in vitro. Mol. Cell 8, 1117-1127.
-
(2001)
Mol. Cell
, vol.8
, pp. 1117-1127
-
-
Chen, X.B.1
Melchionna, R.2
Denis, C.M.3
Gaillard, P.H.4
Blasina, A.5
Van De Weyer, I.6
Boddy, M.N.7
Russell, P.8
Vialard, J.9
McGowan, C.H.10
-
11
-
-
82255194029
-
Selective and cell-active inhibitors of the USP1/ UAF1 deubiquitinase complex reverse cisplatin resistance in non-small cell lung cancer cells
-
Chen, J., Dexheimer, T.S., Ai, Y., Liang, Q., Villamil, M.A., Inglese, J., Maloney, D.J., Jadhav, A., Simeonov, A., and Zhuang, Z. (2011). Selective and cell-active inhibitors of the USP1/ UAF1 deubiquitinase complex reverse cisplatin resistance in non-small cell lung cancer cells. Chem. Biol. 18, 1390-1400.
-
(2011)
Chem. Biol
, vol.18
, pp. 1390-1400
-
-
Chen, J.1
Dexheimer, T.S.2
Ai, Y.3
Liang, Q.4
Villamil, M.A.5
Inglese, J.6
Maloney, D.J.7
Jadhav, A.8
Simeonov, A.9
Zhuang, Z.10
-
12
-
-
33646582299
-
Chemosensitization to cisplatin by inhibitors of the Fanconi anemia/BRCA pathway
-
Chirnomas, D., Taniguchi, T., de la Vega, M., Vaidya, A.P., Vasserman, M., Hartman, A.R., Kennedy, R., Foster, R., Mahoney, J., Seiden, M.V., et al. (2006). Chemosensitization to cisplatin by inhibitors of the Fanconi anemia/BRCA pathway. Mol. Cancer Ther. 5, 952-961.
-
(2006)
Mol. Cancer Ther
, vol.5
, pp. 952-961
-
-
Chirnomas, D.1
Taniguchi, T.2
De La Vega, M.3
Vaidya, A.P.4
Vasserman, M.5
Hartman, A.R.6
Kennedy, R.7
Foster, R.8
Mahoney, J.9
Seiden, M.V.10
-
13
-
-
84885024085
-
Advances in understanding the complex mechanisms of DNA interstrand cross-link repair
-
Clauson, C., Scharer, O.D., and Niedernhofer, L. (2013). Advances in understanding the complex mechanisms of DNA interstrand cross-link repair. Cold Spring Harbor Perspect. Biol. 5, a012732.
-
(2013)
Cold Spring Harbor Perspect. Biol
, vol.5
, pp. 12732
-
-
Clauson, C.1
Scharer, O.D.2
Niedernhofer, L.3
-
14
-
-
36749082959
-
A UAF1-containing multisubunit protein complex regulates the Fanconi anemia pathway
-
Cohn, M.A., Kowal, P., Yang, K., Haas, W., Huang, T.T., Gygi, S.P., and D’Andrea, A.D. (2007). A UAF1-containing multisubunit protein complex regulates the Fanconi anemia pathway. Mol. Cell 28, 786-797.
-
(2007)
Mol. Cell
, vol.28
, pp. 786-797
-
-
Cohn, M.A.1
Kowal, P.2
Yang, K.3
Haas, W.4
Huang, T.T.5
Gygi, S.P.6
D’Andrea, A.D.7
-
15
-
-
64049107302
-
ATR-dependent phosphorylation of FANCA on serine 1449 after DNA damage is important for FA pathway function
-
Collins, N.B., Wilson, J.B., Bush, T., Thomashevski, A., Roberts, K.J., Jones, N.J., and Kupfer, G.M. (2009). ATR-dependent phosphorylation of FANCA on serine 1449 after DNA damage is important for FA pathway function. Blood 113, 2181-2190.
-
(2009)
Blood
, vol.113
, pp. 2181-2190
-
-
Collins, N.B.1
Wilson, J.B.2
Bush, T.3
Thomashevski, A.4
Roberts, K.J.5
Jones, N.J.6
Kupfer, G.M.7
-
16
-
-
55049111236
-
FANCM and FAAP24 function in ATR-mediated checkpoint signaling independently of the Fanconi anemia core complex
-
Collis, S.J., Ciccia, A., Deans, A.J., Horejsi, Z., Martin, J.S., Maslen, S.L., Skehel, J.M., Elledge, S.J., West, S.C., and Boulton, S.J. (2008). FANCM and FAAP24 function in ATR-mediated checkpoint signaling independently of the Fanconi anemia core complex. Mol. Cell 32, 313-324.
-
(2008)
Mol. Cell
, vol.32
, pp. 313-324
-
-
Collis, S.J.1
Ciccia, A.2
Deans, A.J.3
Horejsi, Z.4
Martin, J.S.5
Maslen, S.L.6
Skehel, J.M.7
Elledge, S.J.8
West, S.C.9
Boulton, S.J.10
-
17
-
-
79957904161
-
FANCP/SLX4: A Swiss army knife of DNA interstrand crosslink repair
-
Cybulski, K.E., and Howlett, N.G. (2011). FANCP/SLX4: a Swiss army knife of DNA interstrand crosslink repair. Cell Cycle 10, 1757-1763.
-
(2011)
Cell Cycle
, vol.10
, pp. 1757-1763
-
-
Cybulski, K.E.1
Howlett, N.G.2
-
18
-
-
77952600845
-
Susceptibility pathways in Fanconi’s anemia and breast cancer
-
D’Andrea, A.D. (2010). Susceptibility pathways in Fanconi’s anemia and breast cancer. N Engl. J. Med. 362, 1909-1919.
-
(2010)
N Engl. J. Med
, vol.362
, pp. 1909-1919
-
-
D’Andrea, A.D.1
-
19
-
-
72149090671
-
FANCM connects the genome instability disorders Bloom’s Syndrome and Fanconi Anemia
-
Deans, A.J., and West, S.C. (2009). FANCM connects the genome instability disorders Bloom’s Syndrome and Fanconi Anemia. Mol. Cell 36, 943-953.
-
(2009)
Mol. Cell
, vol.36
, pp. 943-953
-
-
Deans, A.J.1
West, S.C.2
-
20
-
-
79959635260
-
DNA interstrand crosslink repair and cancer
-
Deans, A.J., and West, S.C. (2011). DNA interstrand crosslink repair and cancer. Nat. Rev. Cancer 11, 467-480.
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 467-480
-
-
Deans, A.J.1
West, S.C.2
-
21
-
-
33845269825
-
Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication
-
Di Micco, R., Fumagalli, M., Cicalese, A., Piccinin, S., Gasparini, P., Luise, C., Schurra, C., Garre, M., Nuciforo, P.G., Bensimon, A., et al. (2006). Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication. Nature 444, 638-642.
-
(2006)
Nature
, vol.444
, pp. 638-642
-
-
Di Micco, R.1
Fumagalli, M.2
Cicalese, A.3
Piccinin, S.4
Gasparini, P.5
Luise, C.6
Schurra, C.7
Garre, M.8
Nuciforo, P.G.9
Bensimon, A.10
-
22
-
-
78650575542
-
Suppression of Rev3, the catalytic subunit of Pol{zeta}, sensitizes drug-resistant lung tumors to chemotherapy
-
Doles, J., Oliver, T.G., Cameron, E.R., Hsu, G., Jacks, T., Walker, G.C., and Hemann, M.T. (2010). Suppression of Rev3, the catalytic subunit of Pol{zeta}, sensitizes drug-resistant lung tumors to chemotherapy. Proc. Natl. Acad. Sci. USA 107, 20786-20791.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 20786-20791
-
-
Doles, J.1
Oliver, T.G.2
Cameron, E.R.3
Hsu, G.4
Jacks, T.5
Walker, G.C.6
Hemann, M.T.7
-
23
-
-
17244373777
-
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
-
Farmer, H., McCabe, N., Lord, C.J., Tutt, A.N., Johnson, D.A., Richardson, T.B., Santarosa, M., Dillon, K.J., Hickson, I., Knights, C., et al. (2005). Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature 434, 917-921.
-
(2005)
Nature
, vol.434
, pp. 917-921
-
-
Farmer, H.1
McCabe, N.2
Lord, C.J.3
Tutt, A.N.4
Johnson, D.A.5
Richardson, T.B.6
Santarosa, M.7
Dillon, K.J.8
Hickson, I.9
Knights, C.10
-
24
-
-
84928551340
-
Replication stress and cancer
-
Gaillard, H., Garcia-Muse, T., and Aguilera, A. (2015). Replication stress and cancer. Nat. Rev. Cancer 15, 276-289.
-
(2015)
Nat. Rev. Cancer
, vol.15
, pp. 276-289
-
-
Gaillard, H.1
Garcia-Muse, T.2
Aguilera, A.3
-
25
-
-
84894412116
-
Why does the bone marrow fail in Fanconi anemia?
-
Garaycoechea, J.I., and Patel, K.J. (2014). Why does the bone marrow fail in Fanconi anemia? Blood 123, 26-34.
-
(2014)
Blood
, vol.123
, pp. 26-34
-
-
Garaycoechea, J.I.1
Patel, K.J.2
-
26
-
-
0035105291
-
Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway
-
Garcia-Higuera, I., Taniguchi, T., Ganesan, S., Meyn, M.S., Timmers, C., Hejna, J., Grompe, M., and D’Andrea, A.D. (2001). Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway. Mol. Cell 7, 249-262.
-
(2001)
Mol. Cell
, vol.7
, pp. 249-262
-
-
Garcia-Higuera, I.1
Taniguchi, T.2
Ganesan, S.3
Meyn, M.S.4
Timmers, C.5
Hejna, J.6
Grompe, M.7
D’Andrea, A.D.8
-
27
-
-
55849133052
-
Remodeling of DNA replication structures by the branch point translocase FANCM
-
Gari, K., Decaillet, C., Delannoy, M., Wu, L., and Constantinou, A. (2008). Remodeling of DNA replication structures by the branch point translocase FANCM. Proc. Natl. Acad. Sci. USA 105, 16107-16112.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 16107-16112
-
-
Gari, K.1
Decaillet, C.2
Delannoy, M.3
Wu, L.4
Constantinou, A.5
-
28
-
-
84920415516
-
Ubiquitin-SUMO circuitry controls activated fanconi anemia ID complex dosage in response to DNA damage
-
Gibbs-Seymour, I., Oka, Y., Rajendra, E., Weinert, B.T., Passmore, L.A., Patel, K.J., Olsen, J.V., Choudhary, C., Bekker-Jensen, S., and Mailand, N. (2015). Ubiquitin-SUMO circuitry controls activated fanconi anemia ID complex dosage in response to DNA damage. Mol. Cell 57, 150-164.
-
(2015)
Mol. Cell
, vol.57
, pp. 150-164
-
-
Gibbs-Seymour, I.1
Oka, Y.2
Rajendra, E.3
Weinert, B.T.4
Passmore, L.A.5
Patel, K.J.6
Olsen, J.V.7
Choudhary, C.8
Bekker-Jensen, S.9
Mailand, N.10
-
29
-
-
78149468904
-
Using synthetic DNA interstrand crosslinks to elucidate repair pathways and identify new therapeutic targets for cancer chemotherapy
-
Guainazzi, A., and Scharer, O.D. (2010). Using synthetic DNA interstrand crosslinks to elucidate repair pathways and identify new therapeutic targets for cancer chemotherapy. Cell Mol Life Sci. 67, 3683-3697.
-
(2010)
Cell Mol Life Sci
, vol.67
, pp. 3683-3697
-
-
Guainazzi, A.1
Scharer, O.D.2
-
30
-
-
84920408083
-
The SLX4 complex is a SUMO e3 ligase that impacts on replication stress outcome and genome stability
-
Guervilly, J.H., Takedachi, A., Naim, V., Scaglione, S., Chawhan, C., Lovera, Y., Despras, E., Kuraoka, I., Kannouche, P., Rosselli, F., et al. (2015). The SLX4 complex is a SUMO e3 ligase that impacts on replication stress outcome and genome stability. Mol. Cell 57, 123-137.
-
(2015)
Mol. Cell
, vol.57
, pp. 123-137
-
-
Guervilly, J.H.1
Takedachi, A.2
Naim, V.3
Scaglione, S.4
Chawhan, C.5
Lovera, Y.6
Despras, E.7
Kuraoka, I.8
Kannouche, P.9
Rosselli, F.10
-
31
-
-
84938667462
-
Mutations in the gene encoding the E2 conjugating enzyme UBE2T cause Fanconi Anemia
-
Hira, A., Yoshida, K., Sato, K., Okuno, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Shimamoto, A., Tahara, H., et al. (2015). Mutations in the gene encoding the E2 conjugating enzyme UBE2T cause Fanconi Anemia. Am. J. Hum. Genet. 96, 1001-1007.
-
(2015)
Am. J. Hum. Genet
, vol.96
, pp. 1001-1007
-
-
Hira, A.1
Yoshida, K.2
Sato, K.3
Okuno, Y.4
Shiraishi, Y.5
Chiba, K.6
Tanaka, H.7
Miyano, S.8
Shimamoto, A.9
Tahara, H.10
-
32
-
-
33748656748
-
Phosphorylation of FANCD2 on two novel sites is required for mitomycin C resistance
-
Ho, G.P., Margossian, S., Taniguchi, T., and D’Andrea, A.D. (2006). Phosphorylation of FANCD2 on two novel sites is required for mitomycin C resistance. Mol. Cell. Biol. 26, 7005-7015.
-
(2006)
Mol. Cell. Biol
, vol.26
, pp. 7005-7015
-
-
Ho, G.P.1
Margossian, S.2
Taniguchi, T.3
D’Andrea, A.D.4
-
33
-
-
84899918056
-
Mouse SLX4 is a tumor suppressor that stimulates the activity of the nuclease XPF-ERCC1 in DNA crosslink repair
-
Hodskinson, M.R., Silhan, J., Crossan, G.P., Garaycoechea, J.I., Mukherjee, S., Johnson, C.M., Scharer, O.D., and Patel, K.J.(2014). Mouse SLX4 is a tumor suppressor that stimulates the activity of the nuclease XPF-ERCC1 in DNA crosslink repair. Mol. Cell 54, 472-484.
-
(2014)
Mol. Cell
, vol.54
, pp. 472-484
-
-
Hodskinson, M.R.1
Silhan, J.2
Crossan, G.P.3
Garaycoechea, J.I.4
Mukherjee, S.5
Johnson, C.M.6
Scharer, O.D.7
Patel, K.J.8
-
34
-
-
77955505023
-
The FANCM/FAAP24 complex is required for the DNA interstrand crosslink-induced checkpoint response
-
Huang, M., Kim, J.M., Shiotani, B., Yang, K., Zou, L., and D’Andrea, A.D. (2010). The FANCM/FAAP24 complex is required for the DNA interstrand crosslink-induced checkpoint response. Mol. Cell 39, 259-268.
-
(2010)
Mol. Cell
, vol.39
, pp. 259-268
-
-
Huang, M.1
Kim, J.M.2
Shiotani, B.3
Yang, K.4
Zou, L.5
D’Andrea, A.D.6
-
35
-
-
82555188036
-
Human MutS and FANCM complexes function as redundant DNA damage sensors in the Fanconi Anemia pathway
-
Huang, M., Kennedy, R., Ali, A.M., Moreau, L.A., Meetei, A.R., D’Andrea, A.D., and Chen, C.C. (2011). Human MutS and FANCM complexes function as redundant DNA damage sensors in the Fanconi Anemia pathway. DNA Repair 10, 1203-1212.
-
(2011)
DNA Repair
, vol.10
, pp. 1203-1212
-
-
Huang, M.1
Kennedy, R.2
Ali, A.M.3
Moreau, L.A.4
Meetei, A.R.5
D’Andrea, A.D.6
Chen, C.C.7
-
36
-
-
84901853112
-
Modularized functions of the Fanconi anemia core complex
-
Huang, Y., Leung, J.W., Lowery, M., Matsushita, N., Wang, Y., Shen, X., Huong, D., Takata, M., Chen, J., and Li, L. (2014). Modularized functions of the Fanconi anemia core complex. Cell Rep. 7, 1849-1857.
-
(2014)
Cell Rep
, vol.7
, pp. 1849-1857
-
-
Huang, Y.1
Leung, J.W.2
Lowery, M.3
Matsushita, N.4
Wang, Y.5
Shen, X.6
Huong, D.7
Takata, M.8
Chen, J.9
Li, L.10
-
37
-
-
55549137026
-
FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway
-
Ishiai, M., Kitao, H., Smogorzewska, A., Tomida, J., Kinomura, A., Uchida, E., Saberi, A., Kinoshita, E., Kinoshita-Kikuta, E., Koike, T., et al. (2008). FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway. Nat. Struct. Mol. Biol. 15, 1138-1146.
-
(2008)
Nat. Struct. Mol. Biol
, vol.15
, pp. 1138-1146
-
-
Ishiai, M.1
Kitao, H.2
Smogorzewska, A.3
Tomida, J.4
Kinomura, A.5
Uchida, E.6
Saberi, A.7
Kinoshita, E.8
Kinoshita-Kikuta, E.9
Koike, T.10
-
38
-
-
34547628200
-
Proteasome function is required for DNA damage response and fanconi anemia pathway activation
-
Jacquemont, C., and Taniguchi, T. (2007). Proteasome function is required for DNA damage response and fanconi anemia pathway activation. Cancer Res. 67, 7395-7405.
-
(2007)
Cancer Res
, vol.67
, pp. 7395-7405
-
-
Jacquemont, C.1
Taniguchi, T.2
-
39
-
-
79960150694
-
Compromised CDK1 activity sensitizes BRCA-proficient cancers to PARP inhibition
-
Johnson, N., Li, Y.C., Walton, Z.E., Cheng, K.A., Li, D., Rodig, S.J., Moreau, L.A., Unitt, C., Bronson, R.T., Thomas, H.D., et al. (2011). Compromised CDK1 activity sensitizes BRCA-proficient cancers to PARP inhibition. Nat. Med. 17, 875-882.
-
(2011)
Nat. Med
, vol.17
, pp. 875-882
-
-
Johnson, N.1
Li, Y.C.2
Walton, Z.E.3
Cheng, K.A.4
Li, D.5
Rodig, S.J.6
Moreau, L.A.7
Unitt, C.8
Bronson, R.T.9
Thomas, H.D.10
-
40
-
-
79960539404
-
Structure of the FANCI-FANCD2 complex: Insights into the Fanconi anemia DNA repair pathway
-
Joo, W., Xu, G., Persky, N.S., Smogorzewska, A., Rudge, D.G., Buzovetsky, O., Elledge, S.J., and Pavletich, N.P. (2011). Structure of the FANCI-FANCD2 complex: insights into the Fanconi anemia DNA repair pathway. Science 333, 312-316.
-
(2011)
Science
, vol.333
, pp. 312-316
-
-
Joo, W.1
Xu, G.2
Persky, N.S.3
Smogorzewska, A.4
Rudge, D.G.5
Buzovetsky, O.6
Elledge, S.J.7
Pavletich, N.P.8
-
41
-
-
84885735554
-
Mutational landscape and significance across 12 major cancer types
-
Kandoth, C., McLellan, M.D., Vandin, F., Ye, K., Niu, B., Lu, C., Xie, M., Zhang, Q., McMichael, J.F., Wyczalkowski, M.A., et al. (2013). Mutational landscape and significance across 12 major cancer types. Nature 502, 333-339.
-
(2013)
Nature
, vol.502
, pp. 333-339
-
-
Kandoth, C.1
McLellan, M.D.2
Vandin, F.3
Ye, K.4
Niu, B.5
Lu, C.6
Xie, M.7
Zhang, Q.8
McMichael, J.F.9
Wyczalkowski, M.A.10
-
42
-
-
84863370346
-
Inhibition of the Nedd8 system sensitizes cells to DNA interstrand cross-linking agents
-
Kee, Y., Huang, M., Chang, S., Moreau, L.A., Park, E., Smith, P.G., and D’Andrea, A.D. (2012). Inhibition of the Nedd8 system sensitizes cells to DNA interstrand cross-linking agents. Mol. Cancer Res. 10, 369-377.
-
(2012)
Mol. Cancer Res
, vol.10
, pp. 369-377
-
-
Kee, Y.1
Huang, M.2
Chang, S.3
Moreau, L.A.4
Park, E.5
Smith, P.G.6
D’Andrea, A.D.7
-
43
-
-
34248184445
-
Fanconi anemia pathway-deficient tumor cells are hypersensitive to inhibition of ataxia telangiectasia mutated
-
Kennedy, R.D., Chen, C.C., Stuckert, P., Archila, E.M., De la Vega, M.A., Moreau, L.A., Shimamura, A., and D’Andrea, A.D. (2007). Fanconi anemia pathway-deficient tumor cells are hypersensitive to inhibition of ataxia telangiectasia mutated. J. Clin. Invest. 117, 1440-1449.
-
(2007)
J. Clin. Invest
, vol.117
, pp. 1440-1449
-
-
Kennedy, R.D.1
Chen, C.C.2
Stuckert, P.3
Archila, E.M.4
De La Vega, M.A.5
Moreau, L.A.6
Shimamura, A.7
D’Andrea, A.D.8
-
44
-
-
84866951386
-
Structural basis of recruitment of DNA polymerase zeta by interaction between REV1 and REV7 proteins
-
Kikuchi, S., Hara, K., Shimizu, T., Sato, M., and Hashimoto, H. (2012). Structural basis of recruitment of DNA polymerase zeta by interaction between REV1 and REV7 proteins. J. Biol. Chem. 287, 33847-33852.
-
(2012)
J. Biol. Chem
, vol.287
, pp. 33847-33852
-
-
Kikuchi, S.1
Hara, K.2
Shimizu, T.3
Sato, M.4
Hashimoto, H.5
-
45
-
-
84930252372
-
Nuclease delivery: Versatile functions of SlX4/fAnCP in genome maintenance
-
Kim, Y. (2014). Nuclease delivery: versatile functions of SlX4/fAnCP in genome maintenance. Mol. Cells 37, 569-574.
-
(2014)
Mol. Cells
, vol.37
, pp. 569-574
-
-
Kim, Y.1
-
46
-
-
84863670930
-
Regulation of DnA cross-link repair by the Fanconi anemia/BRCA pathway
-
Kim, H., and D’Andrea, A.D. (2012). Regulation of DnA cross-link repair by the Fanconi anemia/BRCA pathway. Genes Dev. 26, 1393-1408.
-
(2012)
Genes Dev
, vol.26
, pp. 1393-1408
-
-
Kim, H.1
D’Andrea, A.D.2
-
47
-
-
59649114341
-
Inactivation of murine Usp1 results in genomic instability and a Fanconi anemia phenotype
-
Kim, J.M., Parmar, K., Huang, M., Weinstock, D.M., Ruit, C.A., Kutok, J.L., and D’Andrea, A.D. (2009). Inactivation of murine Usp1 results in genomic instability and a Fanconi anemia phenotype. Dev. Cell 16, 314-320.
-
(2009)
Dev. Cell
, vol.16
, pp. 314-320
-
-
Kim, J.M.1
Parmar, K.2
Huang, M.3
Weinstock, D.M.4
Ruit, C.A.5
Kutok, J.L.6
D’Andrea, A.D.7
-
48
-
-
84862777927
-
Regulation of Rev1 by the Fanconi anemia core complex
-
Kim, H., Yang, K., Dejsuphong, D., and D’Andrea, A.D. (2012). Regulation of Rev1 by the Fanconi anemia core complex. Nat. Struct. Mol. Biol. 19, 164-170.
-
(2012)
Nat. Struct. Mol. Biol
, vol.19
, pp. 164-170
-
-
Kim, H.1
Yang, K.2
Dejsuphong, D.3
D’Andrea, A.D.4
-
49
-
-
84899991195
-
XPF- ERCC1 acts in Unhooking DNA interstrand crosslinks in cooperation with FANCD2 and FANCP/SLX4
-
Klein Douwel, D., Boonen, R.A., Long, D.T., Szypowska, A.A., Raschle, M., Walter, J.C., and Knipscheer, P. (2014). XPF- ERCC1 acts in Unhooking DNA interstrand crosslinks in cooperation with FANCD2 and FANCP/SLX4. Mol. Cell 54, 460-471.
-
(2014)
Mol. Cell
, vol.54
, pp. 460-471
-
-
Klein Douwel, D.1
Boonen, R.A.2
Long, D.T.3
Szypowska, A.A.4
Raschle, M.5
Walter, J.C.6
Knipscheer, P.7
-
50
-
-
72949123930
-
The Fanconi anemia pathway promotes replication-dependent DNA interstrand cross-link repair
-
Knipscheer, P., Raschle, M., Smogorzewska, A., Enoiu, M., Ho, T.V., Scharer, O.D., Elledge, S.J., and Walter, J.C. (2009). The Fanconi anemia pathway promotes replication-dependent DNA interstrand cross-link repair. Science 326, 1698-1701.
-
(2009)
Science
, vol.326
, pp. 1698-1701
-
-
Knipscheer, P.1
Raschle, M.2
Smogorzewska, A.3
Enoiu, M.4
Ho, T.V.5
Scharer, O.D.6
Elledge, S.J.7
Walter, J.C.8
-
51
-
-
84872578210
-
Fanconi anaemia and the repair of Watson and Crick DnA crosslinks
-
Kottemann, M.C., and Smogorzewska, A. (2013). Fanconi anaemia and the repair of Watson and Crick DnA crosslinks. Nature 493, 356-363.
-
(2013)
Nature
, vol.493
, pp. 356-363
-
-
Kottemann, M.C.1
Smogorzewska, A.2
-
52
-
-
58149457080
-
A novel cell-free screen identifies a potent inhibitor of the Fanconi anemia pathway
-
Landais, I., Sobeck, A., Stone, S., LaChapelle, A., and Hoatlin, M.E. (2009). A novel cell-free screen identifies a potent inhibitor of the Fanconi anemia pathway. Int. J. Cancer 124, 783-792.
-
(2009)
Int. J. Cancer
, vol.124
, pp. 783-792
-
-
Landais, I.1
Sobeck, A.2
Stone, S.3
Lachapelle, A.4
Hoatlin, M.E.5
-
53
-
-
79960037006
-
Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice
-
Langevin, F., Crossan, G.P., Rosado, I.V., Arends, M.J., and Patel, K.J. (2011). Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice. Nature 475, 53-58.
-
(2011)
Nature
, vol.475
, pp. 53-58
-
-
Langevin, F.1
Crossan, G.P.2
Rosado, I.V.3
Arends, M.J.4
Patel, K.J.5
-
54
-
-
34249941966
-
Translesion synthesis: Y-family polymerases and the polymerase switch
-
Lehmann, A.R., Niimi, A., Ogi, T., Brown, S., Sabbioneda, S., Wing, J.F., Kannouche, P.L., and Green, C.M. (2007). Translesion synthesis: Y-family polymerases and the polymerase switch. DNA Repair 6, 891-899.
-
(2007)
DNA Repair
, vol.6
, pp. 891-899
-
-
Lehmann, A.R.1
Niimi, A.2
Ogi, T.3
Brown, S.4
Sabbioneda, S.5
Wing, J.F.6
Kannouche, P.L.7
Green, C.M.8
-
55
-
-
84863350996
-
Fanconi anemia (FA) binding protein FAAP20 stabilizes FA complementation group A (FANCA) and participates in interstrand cross-link repair
-
Leung, J.W., Wang, Y., Fong, K.W., Huen, M.S., Li, L., and Chen, J. (2012). Fanconi anemia (FA) binding protein FAAP20 stabilizes FA complementation group A (FANCA) and participates in interstrand cross-link repair. Proc. Natl. Acad. Sci. USA 109, 4491-4496.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 4491-4496
-
-
Leung, J.W.1
Wang, Y.2
Fong, K.W.3
Huen, M.S.4
Li, L.5
Chen, J.6
-
56
-
-
84896603075
-
A selective USP1-UAF1 inhibitor links deubiquitination to DNA damage responses
-
Liang, Q., Dexheimer, T.S., Zhang, P., Rosenthal, A.S., Villamil, M.A., You, C., Zhang, Q., Chen, J., Ott, C.A., Sun, H., et al. (2014). A selective USP1-UAF1 inhibitor links deubiquitination to DNA damage responses. Nat. Chem. Biol. 10, 298-304.
-
(2014)
Nat. Chem. Biol
, vol.10
, pp. 298-304
-
-
Liang, Q.1
Dexheimer, T.S.2
Zhang, P.3
Rosenthal, A.S.4
Villamil, M.A.5
You, C.6
Zhang, Q.7
Chen, J.8
Ott, C.A.9
Sun, H.10
-
57
-
-
84925938228
-
UHRF1 is a sensor for dNa interstrand crosslinks and recruits FANCD2 to initiate the Fanconi anemia pathway
-
Liang, C.C., Zhan, B., Yoshikawa, Y., Haas, W., Gygi, S.P., and Cohn, M.A. (2015). UHRF1 is a sensor for dNa interstrand crosslinks and recruits FANCD2 to initiate the Fanconi anemia pathway. Cell Rep. 10, 1947-1956.
-
(2015)
Cell Rep
, vol.10
, pp. 1947-1956
-
-
Liang, C.C.1
Zhan, B.2
Yoshikawa, Y.3
Haas, W.4
Gygi, S.P.5
Cohn, M.A.6
-
58
-
-
33847307543
-
Role of RAD51C and XRCC3 in genetic recombination and DNA repair
-
Liu, Y., Tarsounas, M., O’Regan, P., and West, S.C. (2007). Role of RAD51C and XRCC3 in genetic recombination and DNA repair. J. Biol. Chem. 282, 1973-1979.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 1973-1979
-
-
Liu, Y.1
Tarsounas, M.2
O’Regan, P.3
West, S.C.4
-
59
-
-
84920996478
-
BRCA1 promotes unloading of the CMG helicase from a stalled DNA replication fork
-
Long, D.T., Joukov, V., Budzowska, M., and Walter, J.C. (2014). BRCA1 promotes unloading of the CMG helicase from a stalled DNA replication fork. Mol. Cell 56, 174-185.
-
(2014)
Mol. Cell
, vol.56
, pp. 174-185
-
-
Long, D.T.1
Joukov, V.2
Budzowska, M.3
Walter, J.C.4
-
60
-
-
84923090502
-
Mammalian polymerase theta promotes alternative NHEJ and suppresses recombination
-
Mateos-Gomez, P.A., Gong, F., Nair, N., Miller, K.M., Lazzerini- Denchi, E., and Sfeir, A. (2015). Mammalian polymerase theta promotes alternative NHEJ and suppresses recombination. Nature 518, 254-257.
-
(2015)
Nature
, vol.518
, pp. 254-257
-
-
Mateos-Gomez, P.A.1
Gong, F.2
Nair, N.3
Miller, K.M.4
Lazzerini- Denchi, E.5
Sfeir, A.6
-
61
-
-
0141484612
-
A novel ubiquitin ligase is deficient in Fanconi anemia
-
Meetei, A.R., de Winter, J.P., Medhurst, A.L., Wallisch, M., Waisfisz, Q., van de Vrugt, H.J., Oostra, A.B., Yan, Z., Ling, C., Bishop, E., et al. (2003). A novel ubiquitin ligase is deficient in Fanconi anemia. Nat. Genet. 35, 165-170.
-
(2003)
Nat. Genet
, vol.35
, pp. 165-170
-
-
Meetei, A.R.1
De Winter, J.P.2
Medhurst, A.L.3
Wallisch, M.4
Waisfisz, Q.5
Van De Vrugt, H.J.6
Oostra, A.B.7
Yan, Z.8
Ling, C.9
Bishop, E.10
-
62
-
-
25144449181
-
A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M
-
Meetei, A.R., Medhurst, A.L., Ling, C., Xue, Y., Singh, T.R., Bier, P., Steltenpool, J., Stone, S., Dokal, I., Mathew, C.G., et al. (2005). A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M. Nat. Genet. 37, 958-963.
-
(2005)
Nat. Genet
, vol.37
, pp. 958-963
-
-
Meetei, A.R.1
Medhurst, A.L.2
Ling, C.3
Xue, Y.4
Singh, T.R.5
Bier, P.6
Steltenpool, J.7
Stone, S.8
Dokal, I.9
Mathew, C.G.10
-
63
-
-
84890525480
-
Small-molecule inhibitors of USP1 target ID1 degradation in leukemic cells
-
Mistry, H., Hsieh, G., Buhrlage, S.J., Huang, M., Park, E., Cuny, G.D., Galinsky, I., Stone, R.M., Gray, N.S., D’Andrea, A.D., et al. (2013). Small-molecule inhibitors of USP1 target ID1 degradation in leukemic cells. Mol. Cancer Ther. 12, 2651-2662.
-
(2013)
Mol. Cancer Ther
, vol.12
, pp. 2651-2662
-
-
Mistry, H.1
Hsieh, G.2
Buhrlage, S.J.3
Huang, M.4
Park, E.5
Cuny, G.D.6
Galinsky, I.7
Stone, R.M.8
Gray, N.S.9
D’Andrea, A.D.10
-
64
-
-
0035099044
-
BRCA2 is required for homology-directed repair of chromosomal breaks
-
Moynahan, M.E., Pierce, A.J., and Jasin, M. (2001). BRCA2 is required for homology-directed repair of chromosomal breaks. Mol. Cell 7, 263-272.
-
(2001)
Mol. Cell
, vol.7
, pp. 263-272
-
-
Moynahan, M.E.1
Pierce, A.J.2
Jasin, M.3
-
65
-
-
77649175453
-
Genomic instability--an evolving hallmark of cancer
-
Negrini, S., Gorgoulis, V.G., and Halazonetis, T.D. (2010). Genomic instability--an evolving hallmark of cancer. Nat. Rev. Mol. Cell Biol. 11, 220-228.
-
(2010)
Nat. Rev. Mol. Cell Biol
, vol.11
, pp. 220-228
-
-
Negrini, S.1
Gorgoulis, V.G.2
Halazonetis, T.D.3
-
66
-
-
4344597147
-
The Fanconi anaemia gene FANCC promotes homologous recombination and error-prone DNA repair
-
Niedzwiedz, W., Mosedale, G., Johnson, M., Ong, C.Y., Pace, P., and Patel, K.J. (2004). The Fanconi anaemia gene FANCC promotes homologous recombination and error-prone DNA repair. Mol. Cell 15, 607-620.
-
(2004)
Mol. Cell
, vol.15
, pp. 607-620
-
-
Niedzwiedz, W.1
Mosedale, G.2
Johnson, M.3
Ong, C.Y.4
Pace, P.5
Patel, K.J.6
-
67
-
-
13244291457
-
The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway
-
Nijman, S.M., Huang, T.T., Dirac, A.M., Brummelkamp, T.R., Kerkhoven, R.M., D’Andrea, A.D., and Bernards, R. (2005). The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway. Mol. Cell 17, 331-339.
-
(2005)
Mol. Cell
, vol.17
, pp. 331-339
-
-
Nijman, S.M.1
Huang, T.T.2
Dirac, A.M.3
Brummelkamp, T.R.4
Kerkhoven, R.M.5
D’Andrea, A.D.6
Bernards, R.7
-
68
-
-
84896786442
-
The carboxyl terminus of FANCE recruits FANCD2 to the Fanconi Anemia (FA) E3 ligase complex to promote the FA DNA repair pathway
-
Polito, D., Cukras, S., Wang, X., Spence, P., Moreau, L., D’Andrea, A.D., and Kee, Y. (2014). The carboxyl terminus of FANCE recruits FANCD2 to the Fanconi Anemia (FA) E3 ligase complex to promote the FA DNA repair pathway. J. Biol. Chem. 289, 7003-7010.
-
(2014)
J. Biol. Chem
, vol.289
, pp. 7003-7010
-
-
Polito, D.1
Cukras, S.2
Wang, X.3
Spence, P.4
Moreau, L.5
D’Andrea, A.D.6
Kee, Y.7
-
69
-
-
84869091913
-
Protein group modification and synergy in the SUMO pathway as exemplified in DNA repair
-
Psakhye, I., and Jentsch, S. (2012). Protein group modification and synergy in the SUMO pathway as exemplified in DNA repair. Cell 151, 807-820.
-
(2012)
Cell
, vol.151
, pp. 807-820
-
-
Psakhye, I.1
Jentsch, S.2
-
70
-
-
84901823876
-
The genetic and biochemical basis of FANCD2 monoubiquitination
-
Rajendra, E., Oestergaard, V.H., Langevin, F., Wang, M., Dornan, G.L., Patel, K.J., and Passmore, L.A. (2014). The genetic and biochemical basis of FANCD2 monoubiquitination. Mol. Cell 54, 858-869.
-
(2014)
Mol. Cell
, vol.54
, pp. 858-869
-
-
Rajendra, E.1
Oestergaard, V.H.2
Langevin, F.3
Wang, M.4
Dornan, G.L.5
Patel, K.J.6
Passmore, L.A.7
-
71
-
-
51549098159
-
Mechanism of replication-coupled DNA interstrand crosslink repair
-
Raschle, M., Knipscheer, P., Enoiu, M., Angelov, T., Sun, J., Griffith, J.D., Ellenberger, T.E., Scharer, O.D., and Walter, J.C. (2008). Mechanism of replication-coupled DNA interstrand crosslink repair. Cell 134, 969-980.
-
(2008)
Cell
, vol.134
, pp. 969-980
-
-
Raschle, M.1
Knipscheer, P.2
Enoiu, M.3
Angelov, T.4
Sun, J.5
Griffith, J.D.6
Ellenberger, T.E.7
Scharer, O.D.8
Walter, J.C.9
-
72
-
-
84929102368
-
DNA repair. Proteomics reveals dynamic assembly of repair complexes during bypass of DNA cross-links
-
Raschle, M., Smeenk, G., Hansen, R.K., Temu, T., Oka, Y., Hein, M.Y., Nagaraj, N., Long, D.T., Walter, J.C., Hofmann, K., et al. (2015). DNA repair. Proteomics reveals dynamic assembly of repair complexes during bypass of DNA cross-links. Science 348, 1253671.
-
(2015)
Science
, vol.348
, pp. 1253671
-
-
Raschle, M.1
Smeenk, G.2
Hansen, R.K.3
Temu, T.4
Oka, Y.5
Hein, M.Y.6
Nagaraj, N.7
Long, D.T.8
Walter, J.C.9
Hofmann, K.10
-
73
-
-
84926505383
-
Biallelic mutations in BRCA1 cause a new Fanconi anemia subtype
-
Sawyer, S.L., Tian, L., Kahkonen, M., Schwartzentruber, J., Kircher, M., Consortium, F.C., Majewski, J., Dyment, D.A., Innes, A.M., et al. University of Washington Centre for Mendelian, G. (2015). Biallelic mutations in BRCA1 cause a new Fanconi anemia subtype. Cancer Discov. 5, 135-142.
-
(2015)
Cancer Discov
, vol.5
, pp. 135-142
-
-
Sawyer, S.L.1
Tian, L.2
Kahkonen, M.3
Schwartzentruber, J.4
Kircher, M.5
Consortium, F.C.6
Majewski, J.7
Dyment, D.A.8
Innes, A.M.9
-
74
-
-
77149135723
-
ATR activation and replication fork restart are defective in FANCM- deficient cells
-
Schwab, R.A., Blackford, A.N., and Niedzwiedz, W. (2010). ATR activation and replication fork restart are defective in FANCM- deficient cells. EMBO J. 29, 806-818.
-
(2010)
EMBO J
, vol.29
, pp. 806-818
-
-
Schwab, R.A.1
Blackford, A.N.2
Niedzwiedz, W.3
-
75
-
-
77949563363
-
MHF1-MHF2, a histone-fold-containing protein complex, participates in the Fanconi anemia pathway via FANCM
-
Singh, T.R., Saro, D., Ali, A.M., Zheng, X.F., Du, C.H., Killen, M.W., Sachpatzidis, A., Wahengbam, K., Pierce, A.J., Xiong, Y., et al. (2010). MHF1-MHF2, a histone-fold-containing protein complex, participates in the Fanconi anemia pathway via FANCM. Mol. Cell 37, 879-886.
-
(2010)
Mol. Cell
, vol.37
, pp. 879-886
-
-
Singh, T.R.1
Saro, D.2
Ali, A.M.3
Zheng, X.F.4
Du, C.H.5
Killen, M.W.6
Sachpatzidis, A.7
Wahengbam, K.8
Pierce, A.J.9
Xiong, Y.10
-
76
-
-
84880860938
-
ATR-dependent phosphorylation of FANCM at serine 1045 is essential for FANCM functions
-
Singh, T.R., Ali, A.M., Paramasivam, M., Pradhan, A., Wahengbam, K., Seidman, M.M., and Meetei, A.R. (2013). ATR-dependent phosphorylation of FANCM at serine 1045 is essential for FANCM functions. Cancer Res. 73, 4300-4310.
-
(2013)
Cancer Res
, vol.73
, pp. 4300-4310
-
-
Singh, T.R.1
Ali, A.M.2
Paramasivam, M.3
Pradhan, A.4
Wahengbam, K.5
Seidman, M.M.6
Meetei, A.R.7
-
77
-
-
34247110291
-
Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair
-
Smogorzewska, A., Matsuoka, S., Vinciguerra, P., McDonald, E.R., 3rd, Hurov, K.E., Luo, J., Ballif, B.A., Gygi, S.P., Hofmann, K., D’Andrea, A.D., et al. (2007). Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair. Cell 129, 289-301.
-
(2007)
Cell
, vol.129
, pp. 289-301
-
-
Smogorzewska, A.1
Matsuoka, S.2
Vinciguerra, P.3
McDonald, E.R.4
Hurov, K.E.5
Luo, J.6
Ballif, B.A.7
Gygi, S.P.8
Hofmann, K.9
D’Andrea, A.D.10
-
78
-
-
77954286076
-
A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair
-
Smogorzewska, A., Desetty, R., Saito, T.T., Schlabach, M., Lach, F.P., Sowa, M.E., Clark, A.B., Kunkel, T.A., Harper, J.W., Colaiacovo, M.P., et al. (2010). A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair. Mol. Cell 39, 36-47.
-
(2010)
Mol. Cell
, vol.39
, pp. 36-47
-
-
Smogorzewska, A.1
Desetty, R.2
Saito, T.T.3
Schlabach, M.4
Lach, F.P.5
Sowa, M.E.6
Clark, A.B.7
Kunkel, T.A.8
Harper, J.W.9
Colaiacovo, M.P.10
-
79
-
-
84925956835
-
UHRF1 Contributes to DNA Damage Repair as a Lesion Recognition Factor and Nuclease Scaffold
-
Tian, Y., Paramasivam, M., Ghosal, G., Chen, D., Shen, X., Huang, Y., Akhter, S., Legerski, R., Chen, J., Seidman, M.M., et al. (2015). UHRF1 Contributes to DNA Damage Repair as a Lesion Recognition Factor and Nuclease Scaffold. Cell Rep. 10, 1957-1966.
-
(2015)
Cell Rep
, vol.10
, pp. 1957-1966
-
-
Tian, Y.1
Paramasivam, M.2
Ghosal, G.3
Chen, D.4
Shen, X.5
Huang, Y.6
Akhter, S.7
Legerski, R.8
Chen, J.9
Seidman, M.M.10
-
80
-
-
84901263371
-
FANCD2 binds CtIP and regulates DNA-end resection during DNA interstrand crosslink repair
-
Unno, J., Itaya, A., Taoka, M., Sato, K., Tomida, J., Sakai, W., Sugasawa, K., Ishiai, M., Ikura, T., Isobe, T., et al. (2014). FANCD2 binds CtIP and regulates DNA-end resection during DNA interstrand crosslink repair. Cell Rep. 7, 1039-1047.
-
(2014)
Cell Rep
, vol.7
, pp. 1039-1047
-
-
Unno, J.1
Itaya, A.2
Taoka, M.3
Sato, K.4
Tomida, J.5
Sakai, W.6
Sugasawa, K.7
Ishiai, M.8
Ikura, T.9
Isobe, T.10
-
81
-
-
77951747926
-
Mutation of the RAD51C gene in a Fanconi anemia-like disorder
-
Vaz, F., Hanenberg, H., Schuster, B., Barker, K., Wiek, C., Erven, V., Neveling, K., Endt, D., Kesterton, I., Autore, F., et al. (2010). Mutation of the RAD51C gene in a Fanconi anemia-like disorder. Nat. Genet. 42, 406-409.
-
(2010)
Nat. Genet
, vol.42
, pp. 406-409
-
-
Vaz, F.1
Hanenberg, H.2
Schuster, B.3
Barker, K.4
Wiek, C.5
Erven, V.6
Neveling, K.7
Endt, D.8
Kesterton, I.9
Autore, F.10
-
82
-
-
84901984431
-
The Fanconi anemia DNA repair pathway: Structural and functional insights into a complex disorder
-
Walden, H., and Deans, A.J. (2014). The Fanconi anemia DNA repair pathway: structural and functional insights into a complex disorder. Ann. Rev. Biophys. 43, 257-278.
-
(2014)
Ann. Rev. Biophys
, vol.43
, pp. 257-278
-
-
Walden, H.1
Deans, A.J.2
-
83
-
-
34047190253
-
Chk1-mediated phosphorylation of FANCE is required for the Fanconi anemia/BRCA pathway
-
Wang, X., Kennedy, R.D., Ray, K., Stuckert, P., Ellenberger, T., and D’Andrea, A.D. (2007). Chk1-mediated phosphorylation of FANCE is required for the Fanconi anemia/BRCA pathway. Mol. Cell. Biol. 27, 3098-3108.
-
(2007)
Mol. Cell. Biol
, vol.27
, pp. 3098-3108
-
-
Wang, X.1
Kennedy, R.D.2
Ray, K.3
Stuckert, P.4
Ellenberger, T.5
D’Andrea, A.D.6
-
84
-
-
70349302817
-
REV3L confers chemoresistance to cisplatin in human gliomas: The potential of its RNAi for synergistic therapy
-
Wang, H., Zhang, S.Y., Wang, S., Lu, J., Wu, W., Weng, L., Chen, D., Zhang, Y., Lu, Z., Yang, J., et al. (2009). REV3L confers chemoresistance to cisplatin in human gliomas: the potential of its RNAi for synergistic therapy. Neuro Oncol. 11, 790-802.
-
(2009)
Neuro Oncol
, vol.11
, pp. 790-802
-
-
Wang, H.1
Zhang, S.Y.2
Wang, S.3
Lu, J.4
Wu, W.5
Weng, L.6
Chen, D.7
Zhang, Y.8
Lu, Z.9
Yang, J.10
-
85
-
-
80052440005
-
Human SNM1A and XPF-ERCC1 collaborate to initiate DNA interstrand cross-link repair
-
Wang, A.T., Sengerova, B., Cattell, E., Inagawa, T., Hartley, J.M., Kiakos, K., Burgess-Brown, N.A., Swift, L.P., Enzlin, J.H., Schofield, C.J., et al. (2011). Human SNM1A and XPF-ERCC1 collaborate to initiate DNA interstrand cross-link repair. Genes Dev. 25, 1859-1870.
-
(2011)
Genes Dev
, vol.25
, pp. 1859-1870
-
-
Wang, A.T.1
Sengerova, B.2
Cattell, E.3
Inagawa, T.4
Hartley, J.M.5
Kiakos, K.6
Burgess-Brown, N.A.7
Swift, L.P.8
Enzlin, J.H.9
Schofield, C.J.10
-
86
-
-
79955968976
-
The E3 ubiquitin ligase RAD18 regulates ubiquitylation and chromatin loading of FANCD2 and FANCI
-
Williams, S.A., Longerich, S., Sung, P., Vaziri, C., and Kupfer, G.M. (2011a). The E3 ubiquitin ligase RAD18 regulates ubiquitylation and chromatin loading of FANCD2 and FANCI. Blood 117, 5078-5087.
-
(2011)
Blood
, vol.117
, pp. 5078-5087
-
-
Williams, S.A.1
Longerich, S.2
Sung, P.3
Vaziri, C.4
Kupfer, G.M.5
-
87
-
-
80052919716
-
USP1 deubiquitinates ID proteins to preserve a mesenchymal stem cell program in osteosarcoma
-
Williams, S.A., Maecker, H.L., French, D.M., Liu, J., Gregg, A., Silverstein, L.B., Cao, T.C., Carano, R.A., and Dixit, V.M. (2011b). USP1 deubiquitinates ID proteins to preserve a mesenchymal stem cell program in osteosarcoma. Cell 146, 918-930.
-
(2011)
Cell
, vol.146
, pp. 918-930
-
-
Williams, S.A.1
Maecker, H.L.2
French, D.M.3
Liu, J.4
Gregg, A.5
Silverstein, L.B.6
Cao, T.C.7
Carano, R.A.8
Dixit, V.M.9
-
88
-
-
80054885247
-
Functional and physical interaction between the mismatch repair and FA-BRCA pathways
-
Williams, S.A., Wilson, J.B., Clark, A.P., Mitson-Salazar, A., Tomashevski, A., Ananth, S., Glazer, P.M., Semmes, O.J., Bale, A.E., Jones, N.J., et al. (2011c). Functional and physical interaction between the mismatch repair and FA-BRCA pathways. Hum. Mol. Genet. 20, 4395-4410.
-
(2011)
Hum. Mol. Genet
, vol.20
, pp. 4395-4410
-
-
Williams, S.A.1
Wilson, J.B.2
Clark, A.P.3
Mitson-Salazar, A.4
Tomashevski, A.5
Ananth, S.6
Glazer, P.M.7
Semmes, O.J.8
Bale, A.E.9
Jones, N.J.10
-
89
-
-
84866948407
-
Structural basis of Rev1-mediated assembly of a quaternary vertebrate translesion polymerase complex consisting of Rev1, heterodimeric polymerase (Pol) zeta, and Pol kappa
-
Wojtaszek, J., Lee, C.J., D’Souza, S., Minesinger, B., Kim, H., D’Andrea, A.D., Walker, G.C., and Zhou, P. (2012). Structural basis of Rev1-mediated assembly of a quaternary vertebrate translesion polymerase complex consisting of Rev1, heterodimeric polymerase (Pol) zeta, and Pol kappa. J. Biol. Chem. 287, 33836-33846.
-
(2012)
J. Biol. Chem
, vol.287
, pp. 33836-33846
-
-
Wojtaszek, J.1
Lee, C.J.2
D’Souza, S.3
Minesinger, B.4
Kim, H.5
D’Andrea, A.D.6
Walker, G.C.7
Zhou, P.8
-
90
-
-
33745200945
-
Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2
-
Xia, B., Sheng, Q., Nakanishi, K., Ohashi, A., Wu, J., Christ, N., Liu, X., Jasin, M., Couch, F.J., and Livingston, D.M. (2006). Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2. Mol. Cell 22, 719-729.
-
(2006)
Mol. Cell
, vol.22
, pp. 719-729
-
-
Xia, B.1
Sheng, Q.2
Nakanishi, K.3
Ohashi, A.4
Wu, J.5
Christ, N.6
Liu, X.7
Jasin, M.8
Couch, F.J.9
Livingston, D.M.10
-
91
-
-
78650580818
-
Error- prone translesion synthesis mediates acquired chemoresistance
-
Xie, K., Doles, J., Hemann, M.T., and Walker, G.C. (2010). Error- prone translesion synthesis mediates acquired chemoresistance. Proc. Natl. Acad. Sci. USA 107, 20792-20797.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 20792-20797
-
-
Xie, K.1
Doles, J.2
Hemann, M.T.3
Walker, G.C.4
-
92
-
-
84926328724
-
RNF4-mediated polyubiquitination regulates the Fanconi anemia/BRCA pathway
-
Xie, J., Kim, H., Moreau, L.A., Puhalla, S., Garber, J., Al Abo, M., Takeda, S., and D’Andrea, A.D. (2015). RNF4-mediated polyubiquitination regulates the Fanconi anemia/BRCA pathway. J. Clin. Invest. 125, 1523-1532.
-
(2015)
J. Clin. Invest
, vol.125
, pp. 1523-1532
-
-
Xie, J.1
Kim, H.2
Moreau, L.A.3
Puhalla, S.4
Garber, J.5
Al Abo, M.6
Takeda, S.7
D’Andrea, A.D.8
-
93
-
-
79955580794
-
Involvement of SLX4 in interstrand cross-link repair is regulated by the Fanconi anemia pathway
-
Yamamoto, K.N., Kobayashi, S., Tsuda, M., Kurumizaka, H., Takata, M., Kono, K., Jiricny, J., Takeda, S., and Hirota, K. (2011). Involvement of SLX4 in interstrand cross-link repair is regulated by the Fanconi anemia pathway. Proc. Natl. Acad. Sci. USA 108, 6492-6496.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 6492-6496
-
-
Yamamoto, K.N.1
Kobayashi, S.2
Tsuda, M.3
Kurumizaka, H.4
Takata, M.5
Kono, K.6
Jiricny, J.7
Takeda, S.8
Hirota, K.9
-
94
-
-
77949701960
-
A histone-fold complex and FANCM form a conserved DNA- remodeling complex to maintain genome stability
-
Yan, Z., Delannoy, M., Ling, C., Daee, D., Osman, F., Muniandy, P.A., Shen, X., Oostra, A.B., Du, H., Steltenpool, J., et al. (2010). A histone-fold complex and FANCM form a conserved DNA- remodeling complex to maintain genome stability. Mol. Cell 37, 865-878.
-
(2010)
Mol. Cell
, vol.37
, pp. 865-878
-
-
Yan, Z.1
Delannoy, M.2
Ling, C.3
Daee, D.4
Osman, F.5
Muniandy, P.A.6
Shen, X.7
Oostra, A.B.8
Du, H.9
Steltenpool, J.10
-
95
-
-
80052437062
-
Regulation of the Fanconi anemia pathway by a SUMO-like delivery network
-
Yang, K., Moldovan, G.L., Vinciguerra, P., Murai, J., Takeda, S., and D’Andrea, A.D. (2011). Regulation of the Fanconi anemia pathway by a SUMO-like delivery network. Genes Dev. 25, 1847-1858.
-
(2011)
Genes Dev
, vol.25
, pp. 1847-1858
-
-
Yang, K.1
Moldovan, G.L.2
Vinciguerra, P.3
Murai, J.4
Takeda, S.5
D’Andrea, A.D.6
-
96
-
-
73649119600
-
Targeting the Fanconi anemia/BRCA pathway circumvents drug resistance in multiple myeloma
-
Yarde, D.N., Oliveira, V., Mathews, L., Wang, X., Villagra, A., Boulware, D., Shain, K.H., Hazlehurst, L.A., Alsina, M., Chen, T., et al. (2009). Targeting the Fanconi anemia/BRCA pathway circumvents drug resistance in multiple myeloma. Cancer Res. 69, 9367-9375.
-
(2009)
Cancer Res
, vol.69
, pp. 9367-9375
-
-
Yarde, D.N.1
Oliveira, V.2
Mathews, L.3
Wang, X.4
Villagra, A.5
Boulware, D.6
Shain, K.H.7
Hazlehurst, L.A.8
Alsina, M.9
Chen, T.10
-
97
-
-
62549115236
-
PALB2 links BRCA1 and BRCA2 in the DNA-damage response
-
Zhang, F., Ma, J., Wu, J., Ye, L., Cai, H., Xia, B., and Yu, X. (2009). PALB2 links BRCA1 and BRCA2 in the DNA-damage response. Curr. Biol. 19, 524-529.
-
(2009)
Curr. Biol
, vol.19
, pp. 524-529
-
-
Zhang, F.1
Ma, J.2
Wu, J.3
Ye, L.4
Cai, H.5
Xia, B.6
Yu, X.7
-
98
-
-
84924269864
-
DNA interstrand cross-link repair requires replication-fork convergence
-
Zhang, J., Dewar, J.M., Budzowska, M., Motnenko, A., Cohn, M.A., and Walter, J.C. (2015). DNA interstrand cross-link repair requires replication-fork convergence. Nat. Struct. Mol. Biol. 22, 242-247.
-
(2015)
Nat. Struct. Mol. Biol
, vol.22
, pp. 242-247
-
-
Zhang, J.1
Dewar, J.M.2
Budzowska, M.3
Motnenko, A.4
Cohn, M.A.5
Walter, J.C.6
-
99
-
-
84864413963
-
FAN1 mutations cause karyomegalic interstitial nephritis, linking chronic kidney failure to defective DNA damage repair
-
Zhou, W., Otto, E.A., Cluckey, A., Airik, R., Hurd, T.W., Chaki, M., Diaz, K., Lach, F.P., Bennett, G.R., Gee, H.Y., et al. (2012). FAN1 mutations cause karyomegalic interstitial nephritis, linking chronic kidney failure to defective DNA damage repair. Nat. Genet. 44, 910-915.
-
(2012)
Nat. Genet
, vol.44
, pp. 910-915
-
-
Zhou, W.1
Otto, E.A.2
Cluckey, A.3
Airik, R.4
Hurd, T.W.5
Chaki, M.6
Diaz, K.7
Lach, F.P.8
Bennett, G.R.9
Gee, H.Y.10
|