The fanconi anemia DNA repair pathway: Structural and functional insights into a complex disorder

Annual Review of Biophysics

Volumn 43, Issue 1, 2014, Pages 257-278

  Walden, Helen ^a   Deans, Andrew J ^b,c  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b ST VINCENT'S INSTITUTE OF MEDICAL RESEARCH   (Australia)

^c UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

DNA repair; Fanconi anemia; Interstrand crosslink; Structural biology; Ubiquitin ligase

Indexed keywords

ADENOSINE TRIPHOSPHATASE; CYCLINE; DOUBLE STRANDED DNA; FAAP100 PROTEIN; FAAP20 PROTEIN; FAAP24 PROTEIN; FANCI PROTEIN; FANCJ PROTEIN; FANCM PROTEIN; FANCN PROTEIN; FANCO PROTEIN; FANCONI ANEMIA ASSOCIATED NUCLEASE 1; FANCONI ANEMIA GROUP A PROTEIN; FANCONI ANEMIA GROUP B PROTEIN; FANCONI ANEMIA GROUP C PROTEIN; FANCONI ANEMIA GROUP D2 PROTEIN; FANCONI ANEMIA GROUP E PROTEIN; FANCONI ANEMIA GROUP F PROTEIN; FANCONI ANEMIA GROUP G PROTEIN; FANCONI ANEMIA GROUP L PROTEIN; FANCONI ANEMIA PROTEIN; FLAP ENDONUCLEASE; MHF1 PROTEIN; MHF2 PROTEIN; PROTEIN; RAD18 PROTEIN; SINGLE STRANDED DNA; SINGLE STRANDED RNA; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; UNINDEXED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CELL CYCLE CHECKPOINT; CELLULAR DISTRIBUTION; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DNA BINDING; DNA BINDING MOTIF; DNA CROSS LINKING; DNA DAMAGE; DNA HAIRPIN; DNA HELIX; DNA REPAIR; ENZYME ACTIVITY; EXCISION REPAIR; FANCONI ANEMIA; FLUORESCENCE POLARIZATION; GEL MOBILITY SHIFT ASSAY; GEL PERMEATION CHROMATOGRAPHY; HOMOLOGOUS RECOMBINATION; HUMAN; INDEL MUTATION; MISMATCH REPAIR; MONOUBIQUITINATION; NUCLEAR LOCALIZATION SIGNAL; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; RING FINGER MOTIF; STOICHIOMETRY; TETRATRICOPEPTIDE REPEAT; UBIQUITINATION; X RAY CRYSTALLOGRAPHY;

DNA REPAIR; FANCONI ANEMIA; INTERSTRAND CROSSLINK; STRUCTURAL BIOLOGY; UBIQUITIN LIGASE;

ANIMALS; DNA DAMAGE; DNA REPAIR; FANCONI ANEMIA; FANCONI ANEMIA COMPLEMENTATION GROUP A PROTEIN; HUMANS; NUCLEAR PROTEINS; UBIQUITIN;

EID: 84901984431     PISSN: 1936122X     EISSN: 19361238     Source Type: Book Series    
DOI: 10.1146/annurev-biophys-051013-022737     Document Type: Article

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