Using synthetic DNA interstrand crosslinks to elucidate repair pathways and identify new therapeutic targets for cancer chemotherapy

Cellular and Molecular Life Sciences

Volumn 67, Issue 21, 2010, Pages 3683-3697

  Guainazzi, Angelo ^a   Schärer, Orlando D ^b  

^a STONY BROOK UNIVERSITY   (United States)

^b NONE

Author keywords

Cancer chemotherapy; Cisplatin; DNA repair; Interstrand crosslinks; Nitrogen mustards

Indexed keywords

CARMUSTINE; CHLORMETHINE DERIVATIVE; CISPLATIN; DNA POLYMERASE; EXCISION REPAIR CROSS COMPLEMENTING PROTEIN 1; FANCONI ANEMIA GROUP C PROTEIN; FANCONI ANEMIA GROUP G PROTEIN; MALONALDEHYDE; MITOMYCIN C; PSORALEN DERIVATIVE;

ANUS CANCER; BILE DUCT CARCINOMA; BRAIN TUMOR; CANCER CHEMOTHERAPY; CANCER RESISTANCE; CARCINOGENESIS; CLINICAL TRIAL; COLORECTAL CANCER; DNA ADDUCT; DNA CROSS LINKING; DNA REPAIR; DNA REPLICATION; DOUBLE STRANDED DNA BREAK; DRUG CYTOTOXICITY; EXCISION REPAIR; FANCONI ANEMIA; GASTROINTESTINAL TUMOR; GENOMIC INSTABILITY; HOMOLOGOUS RECOMBINATION; HUMAN; LIPID PEROXIDATION; LYMPHOMA; MISMATCH REPAIR; NONHUMAN; PANCREAS CANCER; PHOTOACTIVATION; PSORIASIS; REVIEW; SKIN DISEASE; STOMACH CANCER; TESTIS CANCER; ULTRAVIOLET RADIATION; VITILIGO;

ANIMALS; ANTINEOPLASTIC AGENTS; DNA REPAIR; HUMANS; INTERCALATING AGENTS; NEOPLASMS;

BRASSICACEAE;

EID: 78149468904     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-010-0492-6     Document Type: Review

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