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Volumn 16, Issue 12, 2015, Pages 30015-30033

Mesenchymal stem cell-mediated effects of tumor support or suppression

Author keywords

Delivery vehicles; Homing; Mesenchymal stem cells; Tumor microenvironment

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEIN 6; BRAIN DERIVED NEUROTROPHIC FACTOR; EPIDERMAL GROWTH FACTOR; EPITHELIAL DERIVED NEUTROPHIL ACTIVATING FACTOR 78; FIBROBLAST GROWTH FACTOR 2; GAMMA INTERFERON; GRANULOCYTE CHEMOTACTIC PROTEIN 2; INTERLEUKIN 12; INTERLEUKIN 1BETA; INTERLEUKIN 23; INTERLEUKIN 4; INTERLEUKIN 6; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN KINASE B; RANTES; SCATTER FACTOR; SOMATOMEDIN C; STROMAL CELL DERIVED FACTOR 1ALPHA; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN; WNT PROTEIN; X LINKED INHIBITOR OF APOPTOSIS; TUMOR SUPPRESSOR PROTEIN;

EID: 84949953762     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms161226215     Document Type: Article
Times cited : (169)

References (210)
  • 1
    • 33747713246 scopus 로고    scopus 로고
    • Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement
    • [CrossRef] [PubMed]
    • Dominici, M.; le Blanc, K.; Mueller, I.; Slaper-Cortenbach, I.; Marini, F.; Krause, D.; Deans, R.; Keating, A.; Prockop, D.; Horwitz, E. Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy 2006, 8, 315-317. [CrossRef] [PubMed]
    • (2006) Cytotherapy , vol.8 , pp. 315-317
    • Dominici, M.1    le Blanc, K.2    Mueller, I.3    Slaper-Cortenbach, I.4    Marini, F.5    Krause, D.6    Deans, R.7    Keating, A.8    Prockop, D.9    Horwitz, E.10
  • 2
    • 0035889146 scopus 로고    scopus 로고
    • Identification of mesenchymal stem/progenitor cells in human first-trimester fetal blood, liver, and bone marrow
    • [CrossRef] [PubMed]
    • Campagnoli, C.; Roberts, I. A.; Kumar, S.; Bennett, P. R.; Bellantuono, I.; Fisk, N. M. Identification of mesenchymal stem/progenitor cells in human first-trimester fetal blood, liver, and bone marrow. Blood 2001, 98, 2396-2402. [CrossRef] [PubMed]
    • (2001) Blood , vol.98 , pp. 2396-2402
    • Campagnoli, C.1    Roberts, I.A.2    Kumar, S.3    Bennett, P.R.4    Bellantuono, I.5    Fisk, N.M.6
  • 4
    • 0034079140 scopus 로고    scopus 로고
    • Mesenchymal progenitor cells in human umbilical cord blood
    • [CrossRef] [PubMed]
    • Erices, A.; Conget, P.; Minguell, J. J. Mesenchymal progenitor cells in human umbilical cord blood. Br. J. Haematol. 2000, 109, 235-242. [CrossRef] [PubMed]
    • (2000) Br. J. Haematol , vol.109 , pp. 235-242
    • Erices, A.1    Conget, P.2    Minguell, J.J.3
  • 5
    • 0036322544 scopus 로고    scopus 로고
    • Multipotent progenitor cells can be isolated from postnatal murine bone marrow, muscle, and brain
    • [CrossRef]
    • Jiang, Y.; Vaessen, B.; Lenvik, T.; Blackstad, M.; Reyes, M.; Verfaillie, C. M. Multipotent progenitor cells can be isolated from postnatal murine bone marrow, muscle, and brain. Exp. Hematol. 2002, 30, 896-904. [CrossRef]
    • (2002) Exp. Hematol , vol.30 , pp. 896-904
    • Jiang, Y.1    Vaessen, B.2    Lenvik, T.3    Blackstad, M.4    Reyes, M.5    Verfaillie, C.M.6
  • 6
    • 0035450718 scopus 로고    scopus 로고
    • Human reserve pluripotent mesenchymal stem cells are present in the connective tissues of skeletal muscle and dermis derived from fetal, adult, and geriatric donors
    • [CrossRef] [PubMed]
    • Young, H. E.; Steele, T. A.; Bray, R. A.; Hudson, J.; Floyd, J. A.; Hawkins, K.; Thomas, K.; Austin, T.; Edwards, C.; Cuzzourt, J.; et al. Human reserve pluripotent mesenchymal stem cells are present in the connective tissues of skeletal muscle and dermis derived from fetal, adult, and geriatric donors. Anat. Rec. 2001, 264, 51-62. [CrossRef] [PubMed]
    • (2001) Anat. Rec , vol.264 , pp. 51-62
    • Young, H.E.1    Steele, T.A.2    Bray, R.A.3    Hudson, J.4    Floyd, J.A.5    Hawkins, K.6    Thomas, K.7    Austin, T.8    Edwards, C.9    Cuzzourt, J.10
  • 8
    • 70349121293 scopus 로고    scopus 로고
    • Comparison of immunomodulatory properties of mesenchymal stem cells derived from adult human tissues
    • [CrossRef] [PubMed]
    • Yoo, K. H.; Jang, I. K.; Lee, M. W.; Kim, H. E.; Yang, M. S.; Eom, Y.; Lee, J. E.; Kim, Y. J.; Yang, S. K.; Jung, H. L.; et al. Comparison of immunomodulatory properties of mesenchymal stem cells derived from adult human tissues. Cell. Immunol. 2009, 259, 150-156. [CrossRef] [PubMed]
    • (2009) Cell. Immunol , vol.259 , pp. 150-156
    • Yoo, K.H.1    Jang, I.K.2    Lee, M.W.3    Kim, H.E.4    Yang, M.S.5    Eom, Y.6    Lee, J.E.7    Kim, Y.J.8    Yang, S.K.9    Jung, H.L.10
  • 9
    • 84874850959 scopus 로고    scopus 로고
    • Mesenchymal stem cells derived from adipose tissue vs bone marrow: In vitro comparison of their tropism towards gliomas
    • [CrossRef] [PubMed]
    • Pendleton, C.; Li, Q.; Chesler, D. A.; Yuan, K.; Guerrero-Cazares, H.; Quinones-Hinojosa, A. Mesenchymal stem cells derived from adipose tissue vs bone marrow: In vitro comparison of their tropism towards gliomas. PLoS ONE 2013, 8. [CrossRef] [PubMed]
    • (2013) PLoS ONE , pp. 8
    • Pendleton, C.1    Li, Q.2    Chesler, D.A.3    Yuan, K.4    Guerrero-Cazares, H.5    Quinones-Hinojosa, A.6
  • 10
    • 84857411051 scopus 로고    scopus 로고
    • Origins of the tumor microenvironment: Quantitative assessment of adipose-derived and bone marrow-derived stroma
    • [CrossRef] [PubMed]
    • Kidd, S.; Spaeth, E.; Watson, K.; Burks, J.; Lu, H.; Klopp, A.; Andreeff, M.; Marini, F. C. Origins of the tumor microenvironment: Quantitative assessment of adipose-derived and bone marrow-derived stroma. PLoS ONE 2012, 7. [CrossRef] [PubMed]
    • (2012) PLoS ONE , pp. 7
    • Kidd, S.1    Spaeth, E.2    Watson, K.3    Burks, J.4    Lu, H.5    Klopp, A.6    Andreeff, M.7    Marini, F.C.8
  • 12
    • 77956615764 scopus 로고    scopus 로고
    • Human bone marrow and adipose tissue mesenchymal stem cells: A user's guide
    • [CrossRef] [PubMed]
    • Mosna, F.; Sensebe, L.; Krampera, M. Human bone marrow and adipose tissue mesenchymal stem cells: A user's guide. Stem Cells Dev. 2010, 19, 1449-1470. [CrossRef] [PubMed]
    • (2010) Stem Cells Dev , vol.19 , pp. 1449-1470
    • Mosna, F.1    Sensebe, L.2    Krampera, M.3
  • 13
    • 50249158511 scopus 로고    scopus 로고
    • Mesenchymal stem cells in health and disease
    • [CrossRef] [PubMed]
    • Uccelli, A.; Moretta, L.; Pistoia, V. Mesenchymal stem cells in health and disease. Nat. Rev. Immunol. 2008, 8, 726-736. [CrossRef] [PubMed]
    • (2008) Nat. Rev. Immunol , vol.8 , pp. 726-736
    • Uccelli, A.1    Moretta, L.2    Pistoia, V.3
  • 14
    • 66149114386 scopus 로고    scopus 로고
    • Trafficking and differentiation of mesenchymal stem cells
    • [CrossRef] [PubMed]
    • Liu, Z. J.; Zhuge, Y.; Velazquez, O. C. Trafficking and differentiation of mesenchymal stem cells. J. Cell. Biochem. 2009, 106, 984-991. [CrossRef] [PubMed]
    • (2009) J. Cell. Biochem , vol.106 , pp. 984-991
    • Liu, Z.J.1    Zhuge, Y.2    Velazquez, O.C.3
  • 15
    • 0026578530 scopus 로고
    • Characterization of cells with osteogenic potential from human marrow
    • [CrossRef]
    • Haynesworth, S. E.; Goshima, J.; Goldberg, V. M.; Caplan, A. I. Characterization of cells with osteogenic potential from human marrow. Bone 1992, 13, 81-88. [CrossRef]
    • (1992) Bone , vol.13 , pp. 81-88
    • Haynesworth, S.E.1    Goshima, J.2    Goldberg, V.M.3    Caplan, A.I.4
  • 17
    • 0030889354 scopus 로고    scopus 로고
    • Marrow stromal cells as stem cells for nonhematopoietic tissues
    • [CrossRef] [PubMed]
    • Prockop, D. J. Marrow stromal cells as stem cells for nonhematopoietic tissues. Science 1997, 276, 71-74. [CrossRef] [PubMed]
    • (1997) Science , vol.276 , pp. 71-74
    • Prockop, D.J.1
  • 18
    • 56549113250 scopus 로고    scopus 로고
    • The therapeutic potential of bone marrow-derived mesenchymal stem cells on hepatic cirrhosis
    • [CrossRef] [PubMed]
    • Dai, L. J.; Li, H. Y.; Guan, L. X.; Ritchie, G.; Zhou, J. X. The therapeutic potential of bone marrow-derived mesenchymal stem cells on hepatic cirrhosis. Stem Cell Res. 2009, 2, 16-25. [CrossRef] [PubMed]
    • (2009) Stem Cell Res , vol.2 , pp. 16-25
    • Dai, L.J.1    Li, H.Y.2    Guan, L.X.3    Ritchie, G.4    Zhou, J.X.5
  • 19
    • 84900517225 scopus 로고    scopus 로고
    • Mesenchymal stem or stromal cells: A review of clinical applications and manufacturing practices
    • [CrossRef] [PubMed]
    • Sharma, R. R.; Pollock, K.; Hubel, A.; McKenna, D. Mesenchymal stem or stromal cells: A review of clinical applications and manufacturing practices. Transfusion 2014, 54, 1418-1437. [CrossRef] [PubMed]
    • (2014) Transfusion , vol.54 , pp. 1418-1437
    • Sharma, R.R.1    Pollock, K.2    Hubel, A.3    McKenna, D.4
  • 20
    • 18844404360 scopus 로고    scopus 로고
    • Bone marrow mesenchymal progenitor cells inhibit lymphocyte proliferation by activation of the programmed death 1 pathway
    • [CrossRef] [PubMed]
    • Augello, A.; Tasso, R.; Negrini, S. M.; Amateis, A.; Indiveri, F.; Cancedda, R.; Pennesi, G. Bone marrow mesenchymal progenitor cells inhibit lymphocyte proliferation by activation of the programmed death 1 pathway. Eur. J. Immunol. 2005, 35, 1482-1490. [CrossRef] [PubMed]
    • (2005) Eur. J. Immunol , vol.35 , pp. 1482-1490
    • Augello, A.1    Tasso, R.2    Negrini, S.M.3    Amateis, A.4    Indiveri, F.5    Cancedda, R.6    Pennesi, G.7
  • 21
    • 84904129414 scopus 로고    scopus 로고
    • Mechanisms of T-cell immunosuppression by mesenchymal stromal cells: What do we know so far?
    • [CrossRef] [PubMed]
    • Haddad, R.; Saldanha-Araujo, F. Mechanisms of T-cell immunosuppression by mesenchymal stromal cells: What do we know so far? Biomed. Res. Int. 2014, 2014. [CrossRef] [PubMed]
    • (2014) Biomed. Res. Int , pp. 2014
    • Haddad, R.1    Saldanha-Araujo, F.2
  • 22
    • 84870342780 scopus 로고    scopus 로고
    • Immune-related antigens, surface molecules and regulatory factors in human-derived mesenchymal stromal cells: The expression and impact of inflammatory priming
    • [CrossRef] [PubMed]
    • Najar, M.; Raicevic, G.; Fayyad-Kazan, H.; de Bruyn, C.; Bron, D.; Toungouz, M.; Lagneaux, L. Immune-related antigens, surface molecules and regulatory factors in human-derived mesenchymal stromal cells: The expression and impact of inflammatory priming. Stem Cell Rev. 2012, 8, 1188-1198. [CrossRef] [PubMed]
    • (2012) Stem Cell Rev , vol.8 , pp. 1188-1198
    • Najar, M.1    Raicevic, G.2    Fayyad-Kazan, H.3    de Bruyn, C.4    Bron, D.5    Toungouz, M.6    Lagneaux, L.7
  • 23
    • 84887821866 scopus 로고    scopus 로고
    • Proteomic techniques for characterisation of mesenchymal stem cell secretome
    • [CrossRef] [PubMed]
    • Kupcova-Skalnikova, H. Proteomic techniques for characterisation of mesenchymal stem cell secretome. Biochimie 2013, 95, 2196-2211. [CrossRef] [PubMed]
    • (2013) Biochimie , vol.95 , pp. 2196-2211
    • Kupcova-Skalnikova, H.1
  • 24
    • 10644226862 scopus 로고    scopus 로고
    • Transplantation of bone marrow cells reduces CCl4-induced liver fibrosis in mice
    • [CrossRef] [PubMed]
    • Sakaida, I.; Terai, S.; Yamamoto, N.; Aoyama, K.; Ishikawa, T.; Nishina, H.; Okita, K. Transplantation of bone marrow cells reduces CCl4-induced liver fibrosis in mice. Hepatology 2004, 40, 1304-1311. [CrossRef] [PubMed]
    • (2004) Hepatology , vol.40 , pp. 1304-1311
    • Sakaida, I.1    Terai, S.2    Yamamoto, N.3    Aoyama, K.4    Ishikawa, T.5    Nishina, H.6    Okita, K.7
  • 25
    • 84869743329 scopus 로고    scopus 로고
    • Hepatic vascular endothelial growth factor regulates recruitment of rat liver sinusoidal endothelial cell progenitor cells
    • [CrossRef] [PubMed]
    • Wang, L.; Wang, X.; Wang, L.; Chiu, J. D.; van de Ven, G.; Gaarde, W. A.; Deleve, L. D. Hepatic vascular endothelial growth factor regulates recruitment of rat liver sinusoidal endothelial cell progenitor cells. Gastroenterology 2012, 143, 1555-1563. [CrossRef] [PubMed]
    • (2012) Gastroenterology , vol.143 , pp. 1555-1563
    • Wang, L.1    Wang, X.2    Wang, L.3    Chiu, J.D.4    van de Ven, G.5    Gaarde, W.A.6    Deleve, L.D.7
  • 26
    • 84865124384 scopus 로고    scopus 로고
    • The Laennec staging system for histological sub-classification of cirrhosis is useful for stratification of prognosis in patients with liver cirrhosis
    • [CrossRef] [PubMed]
    • Kim, S. U.; Oh, H. J.; Wanless, I. R.; Lee, S.; Han, K. H.; Park, Y. N. The Laennec staging system for histological sub-classification of cirrhosis is useful for stratification of prognosis in patients with liver cirrhosis. J. Hepatol. 2012, 57, 556-563. [CrossRef] [PubMed]
    • (2012) J. Hepatol , vol.57 , pp. 556-563
    • Kim, S.U.1    Oh, H.J.2    Wanless, I.R.3    Lee, S.4    Han, K.H.5    Park, Y.N.6
  • 27
    • 77952355716 scopus 로고    scopus 로고
    • Concise review: Bone marrow-derived stem/progenitor cells in cutaneous repair and regeneration
    • [PubMed]
    • Wu, Y.; Zhao, R. C.; Tredget, E. E. Concise review: Bone marrow-derived stem/progenitor cells in cutaneous repair and regeneration. Stem Cells 2010, 28, 905-915. [PubMed]
    • (2010) Stem Cells , vol.28 , pp. 905-915
    • Wu, Y.1    Zhao, R.C.2    Tredget, E.E.3
  • 28
    • 41549105367 scopus 로고    scopus 로고
    • Human mesenchymal stem cells stimulated by TNF-α, LPS, or hypoxia produce growth factors by an NFkB-but not JNK-dependent mechanism
    • [CrossRef] [PubMed]
    • Crisostomo, P. R.; Wang, Y.; Markel, T. A.; Wang, M.; Lahm, T.; Meldrum, D. R. Human mesenchymal stem cells stimulated by TNF-α, LPS, or hypoxia produce growth factors by an NFkB-but not JNK-dependent mechanism. Am. J. Physiol. Cell Physiol. 2008, 294, C675-C682. [CrossRef] [PubMed]
    • (2008) Am. J. Physiol. Cell Physiol , vol.294 , pp. C675-C682
    • Crisostomo, P.R.1    Wang, Y.2    Markel, T.A.3    Wang, M.4    Lahm, T.5    Meldrum, D.R.6
  • 29
    • 33746424373 scopus 로고    scopus 로고
    • Mesenchymal stem cells as trophic mediators
    • [CrossRef] [PubMed]
    • Caplan, A. I.; Dennis, J. E. Mesenchymal stem cells as trophic mediators. J. Cell. Biochem. 2006, 98, 1076-1084. [CrossRef] [PubMed]
    • (2006) J. Cell. Biochem , vol.98 , pp. 1076-1084
    • Caplan, A.I.1    Dennis, J.E.2
  • 31
    • 65249161144 scopus 로고    scopus 로고
    • Multipotent stromal cells are activated to reduce apoptosis in part by upregulation and secretion of stanniocalcin-1
    • [CrossRef] [PubMed]
    • Block, G. J.; Ohkouchi, S.; Fung, F.; Frenkel, J.; Gregory, C.; Pochampally, R.; DiMattia, G.; Sullivan, D. E.; Prockop, D. J. Multipotent stromal cells are activated to reduce apoptosis in part by upregulation and secretion of stanniocalcin-1. Stem Cells 2009, 27, 670-681. [CrossRef] [PubMed]
    • (2009) Stem Cells , vol.27 , pp. 670-681
    • Block, G.J.1    Ohkouchi, S.2    Fung, F.3    Frenkel, J.4    Gregory, C.5    Pochampally, R.6    DiMattia, G.7    Sullivan, D.E.8    Prockop, D.J.9
  • 32
    • 0022891340 scopus 로고
    • Tumors: Wounds that do not heal. Similarities between tumor stroma generation and wound healing
    • [PubMed]
    • Dvorak, H. F. Tumors: Wounds that do not heal. Similarities between tumor stroma generation and wound healing. N. Engl. J. Med. 1986, 315, 1650-1659. [PubMed]
    • (1986) N. Engl. J. Med , vol.315 , pp. 1650-1659
    • Dvorak, H.F.1
  • 34
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • [CrossRef] [PubMed]
    • Hanahan, D.; Weinberg, R. A. Hallmarks of cancer: The next generation. Cell 2011, 144, 646-674. [CrossRef] [PubMed]
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 35
    • 79951841819 scopus 로고    scopus 로고
    • Concise review: Dissecting a discrepancy in the literature: Do mesenchymal stem cells support or suppress tumor growth?
    • [CrossRef] [PubMed]
    • Klopp, A. H.; Gupta, A.; Spaeth, E.; Andreeff, M.; Marini, F., 3rd. Concise review: Dissecting a discrepancy in the literature: Do mesenchymal stem cells support or suppress tumor growth? Stem Cells 2011, 29, 11-19. [CrossRef] [PubMed]
    • (2011) Stem Cells , vol.29 , pp. 11-19
    • Klopp, A.H.1    Gupta, A.2    Spaeth, E.3    Andreeff, M.4    Marini, F.5    3rd6
  • 37
    • 80052537717 scopus 로고    scopus 로고
    • Adipose tissue derived stem cells differentiate into carcinoma-associated fibroblast-like cells under the influence of tumor derived factors
    • [CrossRef] [PubMed]
    • Jotzu, C.; Alt, E.; Welte, G.; Li, J.; Hennessy, B. T.; Devarajan, E.; Krishnappa, S.; Pinilla, S.; Droll, L.; Song, Y. H. Adipose tissue derived stem cells differentiate into carcinoma-associated fibroblast-like cells under the influence of tumor derived factors. Cell. Oncol. 2011, 34, 55-67. [CrossRef] [PubMed]
    • (2011) Cell. Oncol , vol.34 , pp. 55-67
    • Jotzu, C.1    Alt, E.2    Welte, G.3    Li, J.4    Hennessy, B.T.5    Devarajan, E.6    Krishnappa, S.7    Pinilla, S.8    Droll, L.9    Song, Y.H.10
  • 38
    • 69049098045 scopus 로고    scopus 로고
    • Tissue resident stem cells produce CCL5 under the influence of cancer cells and thereby promote breast cancer cell invasion
    • [CrossRef] [PubMed]
    • Pinilla, S.; Alt, E.; Abdul Khalek, F. J.; Jotzu, C.; Muehlberg, F.; Beckmann, C.; Song, Y. H. Tissue resident stem cells produce CCL5 under the influence of cancer cells and thereby promote breast cancer cell invasion. Cancer Lett. 2009, 284, 80-85. [CrossRef] [PubMed]
    • (2009) Cancer Lett , vol.284 , pp. 80-85
    • Pinilla, S.1    Alt, E.2    Abdul Khalek, F.J.3    Jotzu, C.4    Muehlberg, F.5    Beckmann, C.6    Song, Y.H.7
  • 39
    • 67349111975 scopus 로고    scopus 로고
    • CXCR4 receptor positive spheroid forming cells are responsible for tumor invasion in vitro
    • [CrossRef] [PubMed]
    • Krohn, A.; Song, Y. H.; Muehlberg, F.; Droll, L.; Beckmann, C.; Alt, E. CXCR4 receptor positive spheroid forming cells are responsible for tumor invasion in vitro. Cancer Lett. 2009, 280, 65-71. [CrossRef] [PubMed]
    • (2009) Cancer Lett , vol.280 , pp. 65-71
    • Krohn, A.1    Song, Y.H.2    Muehlberg, F.3    Droll, L.4    Beckmann, C.5    Alt, E.6
  • 41
    • 41849115243 scopus 로고    scopus 로고
    • Suppression of tumorigenesis by human mesenchymal stem cells in a hepatoma model
    • [CrossRef] [PubMed]
    • Qiao, L.; Xu, Z.; Zhao, T.; Zhao, Z.; Shi, M.; Zhao, R. C.; Ye, L.; Zhang, X. Suppression of tumorigenesis by human mesenchymal stem cells in a hepatoma model. Cell Res. 2008, 18, 500-507. [CrossRef] [PubMed]
    • (2008) Cell Res , vol.18 , pp. 500-507
    • Qiao, L.1    Xu, Z.2    Zhao, T.3    Zhao, Z.4    Shi, M.5    Zhao, R.C.6    Ye, L.7    Zhang, X.8
  • 42
    • 49349100584 scopus 로고    scopus 로고
    • Dkk-1 secreted by mesenchymal stem cells inhibits growth of breast cancer cells via depression of Wnt signalling
    • [CrossRef] [PubMed]
    • Qiao, L.; Xu, Z. L.; Zhao, T. J.; Ye, L. H.; Zhang, X. D. Dkk-1 secreted by mesenchymal stem cells inhibits growth of breast cancer cells via depression of Wnt signalling. Cancer Lett. 2008, 269, 67-77. [CrossRef] [PubMed]
    • (2008) Cancer Lett , vol.269 , pp. 67-77
    • Qiao, L.1    Xu, Z.L.2    Zhao, T.J.3    Ye, L.H.4    Zhang, X.D.5
  • 43
    • 67349195445 scopus 로고    scopus 로고
    • Human mesenchymal stem cells inhibit cancer cell proliferation by secreting DKK-1
    • [CrossRef] [PubMed]
    • Zhu, Y.; Sun, Z.; Han, Q.; Liao, L.; Wang, J.; Bian, C.; Li, J.; Yan, X.; Liu, Y.; Shao, C.; et al. Human mesenchymal stem cells inhibit cancer cell proliferation by secreting DKK-1. Leukemia 2009, 23, 925-933. [CrossRef] [PubMed]
    • (2009) Leukemia , vol.23 , pp. 925-933
    • Zhu, Y.1    Sun, Z.2    Han, Q.3    Liao, L.4    Wang, J.5    Bian, C.6    Li, J.7    Yan, X.8    Liu, Y.9    Shao, C.10
  • 44
    • 67650869280 scopus 로고    scopus 로고
    • Adult stromal cells derived from human adipose tissue provoke pancreatic cancer cell death both in vitro and in vivo
    • [CrossRef] [PubMed]
    • Cousin, B.; Ravet, E.; Poglio, S.; de Toni, F.; Bertuzzi, M.; Lulka, H.; Touil, I.; Andre, M.; Grolleau, J. L.; Peron, J. M.; et al. Adult stromal cells derived from human adipose tissue provoke pancreatic cancer cell death both in vitro and in vivo. PLoS ONE 2009, 4. [CrossRef] [PubMed]
    • (2009) PLoS ONE , pp. 4
    • Cousin, B.1    Ravet, E.2    Poglio, S.3    de Toni, F.4    Bertuzzi, M.5    Lulka, H.6    Touil, I.7    Andre, M.8    Grolleau, J.L.9    Peron, J.M.10
  • 45
    • 77955590310 scopus 로고    scopus 로고
    • Upregulation of PTEN in glioma cells by cord blood mesenchymal stem cells inhibits migration via downregulation of the PI3K/Akt pathway
    • [CrossRef] [PubMed]
    • Dasari, V. R.; Kaur, K.; Velpula, K. K.; Gujrati, M.; Fassett, D.; Klopfenstein, J. D.; Dinh, D. H.; Rao, J. S. Upregulation of PTEN in glioma cells by cord blood mesenchymal stem cells inhibits migration via downregulation of the PI3K/Akt pathway. PLoS ONE 2010, 5. [CrossRef] [PubMed]
    • (2010) PLoS ONE , pp. 5
    • Dasari, V.R.1    Kaur, K.2    Velpula, K.K.3    Gujrati, M.4    Fassett, D.5    Klopfenstein, J.D.6    Dinh, D.H.7    Rao, J.S.8
  • 46
    • 77955645493 scopus 로고    scopus 로고
    • Cord blood stem cell-mediated induction of apoptosis in glioma downregulates X-linked inhibitor of apoptosis protein (XIAP)
    • [CrossRef] [PubMed]
    • Dasari, V. R.; Velpula, K. K.; Kaur, K.; Fassett, D.; Klopfenstein, J. D.; Dinh, D. H.; Gujrati, M.; Rao, J. S. Cord blood stem cell-mediated induction of apoptosis in glioma downregulates X-linked inhibitor of apoptosis protein (XIAP). PLoS ONE 2010, 5. [CrossRef] [PubMed]
    • (2010) PLoS ONE , pp. 5
    • Dasari, V.R.1    Velpula, K.K.2    Kaur, K.3    Fassett, D.4    Klopfenstein, J.D.5    Dinh, D.H.6    Gujrati, M.7    Rao, J.S.8
  • 47
    • 66149135956 scopus 로고    scopus 로고
    • Concentration-dependent inhibition of angiogenesis by mesenchymal stem cells
    • [CrossRef] [PubMed]
    • Otsu, K.; Das, S.; Houser, S. D.; Quadri, S. K.; Bhattacharya, S.; Bhattacharya, J. Concentration-dependent inhibition of angiogenesis by mesenchymal stem cells. Blood 2009, 113, 4197-4205. [CrossRef] [PubMed]
    • (2009) Blood , vol.113 , pp. 4197-4205
    • Otsu, K.1    Das, S.2    Houser, S.D.3    Quadri, S.K.4    Bhattacharya, S.5    Bhattacharya, J.6
  • 48
    • 34447276000 scopus 로고    scopus 로고
    • Tumor microenvironment: The role of the tumor stroma in cancer
    • [CrossRef] [PubMed]
    • Li, H.; Fan, X.; Houghton, J. Tumor microenvironment: The role of the tumor stroma in cancer. J. Cell. Biochem. 2007, 101, 805-815. [CrossRef] [PubMed]
    • (2007) J. Cell. Biochem , vol.101 , pp. 805-815
    • Li, H.1    Fan, X.2    Houghton, J.3
  • 49
    • 0035495401 scopus 로고    scopus 로고
    • Putting tumours in context
    • [CrossRef] [PubMed]
    • Bissell, M. J.; Radisky, D. Putting tumours in context. Nat. Rev. Cancer 2001, 1, 46-54. [CrossRef] [PubMed]
    • (2001) Nat. Rev. Cancer , vol.1 , pp. 46-54
    • Bissell, M.J.1    Radisky, D.2
  • 51
    • 70350243071 scopus 로고    scopus 로고
    • Direct evidence of mesenchymal stem cell tropism for tumor and wounding microenvironments using in vivo bioluminescent imaging
    • [CrossRef] [PubMed]
    • Kidd, S.; Spaeth, E.; Dembinski, J. L.; Dietrich, M.; Watson, K.; Klopp, A.; Battula, V. L.; Weil, M.; Andreeff, M.; Marini, F. C. Direct evidence of mesenchymal stem cell tropism for tumor and wounding microenvironments using in vivo bioluminescent imaging. Stem Cells 2009, 27, 2614-2623. [CrossRef] [PubMed]
    • (2009) Stem Cells , vol.27 , pp. 2614-2623
    • Kidd, S.1    Spaeth, E.2    Dembinski, J.L.3    Dietrich, M.4    Watson, K.5    Klopp, A.6    Battula, V.L.7    Weil, M.8    Andreeff, M.9    Marini, F.C.10
  • 53
    • 67349110806 scopus 로고    scopus 로고
    • Human mesenchymal stem cells (HMSCs) target osteosarcoma and promote its growth and pulmonary metastasis
    • [CrossRef] [PubMed]
    • Xu, W. T.; Bian, Z. Y.; Fan, Q. M.; Li, G.; Tang, T. T. Human mesenchymal stem cells (HMSCs) target osteosarcoma and promote its growth and pulmonary metastasis. Cancer Lett. 2009, 281, 32-41. [CrossRef] [PubMed]
    • (2009) Cancer Lett , vol.281 , pp. 32-41
    • Xu, W.T.1    Bian, Z.Y.2    Fan, Q.M.3    Li, G.4    Tang, T.T.5
  • 54
    • 33646502840 scopus 로고    scopus 로고
    • Mesenchymal stem cells derived from bone marrow favor tumor cell growth in vivo
    • [CrossRef] [PubMed]
    • Zhu, W.; Xu, W.; Jiang, R.; Qian, H.; Chen, M.; Hu, J.; Cao, W.; Han, C.; Chen, Y. Mesenchymal stem cells derived from bone marrow favor tumor cell growth in vivo. Exp. Mol. Pathol. 2006, 80, 267-274. [CrossRef] [PubMed]
    • (2006) Exp. Mol. Pathol , vol.80 , pp. 267-274
    • Zhu, W.1    Xu, W.2    Jiang, R.3    Qian, H.4    Chen, M.5    Hu, J.6    Cao, W.7    Han, C.8    Chen, Y.9
  • 55
    • 64549145804 scopus 로고    scopus 로고
    • Mesenchymal stem cell transition to tumor-associated fibroblasts contributes to fibrovascular network expansion and tumor progression
    • [CrossRef] [PubMed]
    • Spaeth, E. L.; Dembinski, J. L.; Sasser, A. K.; Watson, K.; Klopp, A.; Hall, B.; Andreeff, M.; Marini, F. Mesenchymal stem cell transition to tumor-associated fibroblasts contributes to fibrovascular network expansion and tumor progression. PLoS ONE 2009, 4. [CrossRef] [PubMed]
    • (2009) PLoS ONE , pp. 4
    • Spaeth, E.L.1    Dembinski, J.L.2    Sasser, A.K.3    Watson, K.4    Klopp, A.5    Hall, B.6    Andreeff, M.7    Marini, F.8
  • 56
    • 0242410394 scopus 로고    scopus 로고
    • Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animals
    • [CrossRef] [PubMed]
    • Djouad, F.; Plence, P.; Bony, C.; Tropel, P.; Apparailly, F.; Sany, J.; Noel, D.; Jorgensen, C. Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animals. Blood 2003, 102, 3837-3844. [CrossRef] [PubMed]
    • (2003) Blood , vol.102 , pp. 3837-3844
    • Djouad, F.1    Plence, P.2    Bony, C.3    Tropel, P.4    Apparailly, F.5    Sany, J.6    Noel, D.7    Jorgensen, C.8
  • 57
    • 8144228952 scopus 로고    scopus 로고
    • Friends or foes-Bipolar effects of the tumour stroma in cancer
    • [CrossRef] [PubMed]
    • Mueller, M. M.; Fusenig, N. E. Friends or foes-Bipolar effects of the tumour stroma in cancer. Nat. Rev. Cancer 2004, 4, 839-849. [CrossRef] [PubMed]
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 839-849
    • Mueller, M.M.1    Fusenig, N.E.2
  • 58
    • 0023939143 scopus 로고
    • Smooth-muscle differentiation in stromal cells of malignant and non-malignant breast tissues
    • [CrossRef] [PubMed]
    • Sappino, A. P.; Skalli, O.; Jackson, B.; Schurch, W.; Gabbiani, G. Smooth-muscle differentiation in stromal cells of malignant and non-malignant breast tissues. Int. J. Cancer 1988, 41, 707-712. [CrossRef] [PubMed]
    • (1988) Int. J. Cancer , vol.41 , pp. 707-712
    • Sappino, A.P.1    Skalli, O.2    Jackson, B.3    Schurch, W.4    Gabbiani, G.5
  • 59
    • 18844428327 scopus 로고    scopus 로고
    • Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
    • [CrossRef] [PubMed]
    • Orimo, A.; Gupta, P. B.; Sgroi, D. C.; Arenzana-Seisdedos, F.; Delaunay, T.; Naeem, R.; Carey, V. J.; Richardson, A. L.; Weinberg, R. A. Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 2005, 121, 335-348. [CrossRef] [PubMed]
    • (2005) Cell , vol.121 , pp. 335-348
    • Orimo, A.1    Gupta, P.B.2    Sgroi, D.C.3    Arenzana-Seisdedos, F.4    Delaunay, T.5    Naeem, R.6    Carey, V.J.7    Richardson, A.L.8    Weinberg, R.A.9
  • 62
    • 79751501829 scopus 로고    scopus 로고
    • Bone marrow-derived myofibroblasts contribute to the mesenchymal stem cell niche and promote tumor growth
    • [CrossRef] [PubMed]
    • Quante, M.; Tu, S. P.; Tomita, H.; Gonda, T.; Wang, S. S.; Takashi, S.; Baik, G. H.; Shibata, W.; Diprete, B.; Betz, K. S.; et al. Bone marrow-derived myofibroblasts contribute to the mesenchymal stem cell niche and promote tumor growth. Cancer Cell 2011, 19, 257-272. [CrossRef] [PubMed]
    • (2011) Cancer Cell , vol.19 , pp. 257-272
    • Quante, M.1    Tu, S.P.2    Tomita, H.3    Gonda, T.4    Wang, S.S.5    Takashi, S.6    Baik, G.H.7    Shibata, W.8    Diprete, B.9    Betz, K.S.10
  • 63
    • 6344281040 scopus 로고    scopus 로고
    • Proteomic profiling of bone marrow mesenchymal stem cells upon transforming growth factor β1 stimulation
    • [CrossRef] [PubMed]
    • Wang, D.; Park, J. S.; Chu, J. S.; Krakowski, A.; Luo, K.; Chen, D. J.; Li, S. Proteomic profiling of bone marrow mesenchymal stem cells upon transforming growth factor β1 stimulation. J. Biol. Chem. 2004, 279, 43725-43734. [CrossRef] [PubMed]
    • (2004) J. Biol. Chem , vol.279 , pp. 43725-43734
    • Wang, D.1    Park, J.S.2    Chu, J.S.3    Krakowski, A.4    Luo, K.5    Chen, D.J.6    Li, S.7
  • 64
    • 84880276438 scopus 로고    scopus 로고
    • Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells
    • [CrossRef] [PubMed]
    • Robbins, P. F.; Lu, Y. C.; El-Gamil, M.; Li, Y. F.; Gross, C.; Gartner, J.; Lin, J. C.; Teer, J. K.; Cliften, P.; Tycksen, E.; et al. Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells. Nat. Med. 2013, 19, 747-752. [CrossRef] [PubMed]
    • (2013) Nat. Med , vol.19 , pp. 747-752
    • Robbins, P.F.1    Lu, Y.C.2    El-Gamil, M.3    Li, Y.F.4    Gross, C.5    Gartner, J.6    Lin, J.C.7    Teer, J.K.8    Cliften, P.9    Tycksen, E.10
  • 66
    • 33845524204 scopus 로고    scopus 로고
    • Role of tumor-associated macrophages in tumor progression and invasion
    • [CrossRef] [PubMed]
    • Mantovani, A.; Schioppa, T.; Porta, C.; Allavena, P.; Sica, A. Role of tumor-associated macrophages in tumor progression and invasion. Cancer Metastasis Rev. 2006, 25, 315-322. [CrossRef] [PubMed]
    • (2006) Cancer Metastasis Rev , vol.25 , pp. 315-322
    • Mantovani, A.1    Schioppa, T.2    Porta, C.3    Allavena, P.4    Sica, A.5
  • 67
    • 33645991795 scopus 로고    scopus 로고
    • Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: Potential targets of anti-cancer therapy
    • [CrossRef] [PubMed]
    • Sica, A.; Schioppa, T.; Mantovani, A.; Allavena, P. Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: Potential targets of anti-cancer therapy. Eur. J. Cancer 2006, 42, 717-727. [CrossRef] [PubMed]
    • (2006) Eur. J. Cancer , vol.42 , pp. 717-727
    • Sica, A.1    Schioppa, T.2    Mantovani, A.3    Allavena, P.4
  • 68
    • 31044433663 scopus 로고    scopus 로고
    • Macrophages: Obligate partners for tumor cell migration, invasion, and metastasis
    • [CrossRef] [PubMed]
    • Condeelis, J.; Pollard, J. W. Macrophages: Obligate partners for tumor cell migration, invasion, and metastasis. Cell 2006, 124, 263-266. [CrossRef] [PubMed]
    • (2006) Cell , vol.124 , pp. 263-266
    • Condeelis, J.1    Pollard, J.W.2
  • 69
    • 33751551172 scopus 로고    scopus 로고
    • Dual role of macrophages in tumor growth and angiogenesis
    • [CrossRef] [PubMed]
    • Lamagna, C.; Aurrand-Lions, M.; Imhof, B. A. Dual role of macrophages in tumor growth and angiogenesis. J. Leukoc. Biol. 2006, 80, 705-713. [CrossRef] [PubMed]
    • (2006) J. Leukoc. Biol , vol.80 , pp. 705-713
    • Lamagna, C.1    Aurrand-Lions, M.2    Imhof, B.A.3
  • 70
    • 68949114117 scopus 로고    scopus 로고
    • Tumor-associated macrophages: Effectors of angiogenesis and tumor progression
    • [CrossRef] [PubMed]
    • Coffelt, S. B.; Hughes, R.; Lewis, C. E. Tumor-associated macrophages: Effectors of angiogenesis and tumor progression. Biochim. Biophys. Acta 2009, 1796, 11-18. [CrossRef] [PubMed]
    • (2009) Biochim. Biophys. Acta , vol.1796 , pp. 11-18
    • Coffelt, S.B.1    Hughes, R.2    Lewis, C.E.3
  • 71
    • 67349168435 scopus 로고    scopus 로고
    • Role of macrophages in tumour progression
    • [CrossRef] [PubMed]
    • Siveen, K. S.; Kuttan, G. Role of macrophages in tumour progression. Immunol. Lett. 2009, 123, 97-102. [CrossRef] [PubMed]
    • (2009) Immunol. Lett , vol.123 , pp. 97-102
    • Siveen, K.S.1    Kuttan, G.2
  • 72
    • 31544441610 scopus 로고    scopus 로고
    • Distinct role of macrophages in different tumor microenvironments
    • [CrossRef] [PubMed]
    • Lewis, C. E.; Pollard, J. W. Distinct role of macrophages in different tumor microenvironments. Cancer Res. 2006, 66, 605-612. [CrossRef] [PubMed]
    • (2006) Cancer Res , vol.66 , pp. 605-612
    • Lewis, C.E.1    Pollard, J.W.2
  • 73
    • 65049084189 scopus 로고    scopus 로고
    • Tumor-associated macrophages and the related myeloid-derived suppressor cells as a paradigm of the diversity of macrophage activation
    • [CrossRef] [PubMed]
    • Mantovani, A.; Sica, A.; Allavena, P.; Garlanda, C.; Locati, M. Tumor-associated macrophages and the related myeloid-derived suppressor cells as a paradigm of the diversity of macrophage activation. Hum. Immunol. 2009, 70, 325-330. [CrossRef] [PubMed]
    • (2009) Hum. Immunol , vol.70 , pp. 325-330
    • Mantovani, A.1    Sica, A.2    Allavena, P.3    Garlanda, C.4    Locati, M.5
  • 74
    • 0034659784 scopus 로고    scopus 로고
    • M-1/M-2 macrophages and the Th1/Th2 paradigm
    • [CrossRef] [PubMed]
    • Mills, C. D.; Kincaid, K.; Alt, J. M.; Heilman, M. J.; Hill, A. M. M-1/M-2 macrophages and the Th1/Th2 paradigm. J. Immunol. 2000, 164, 6166-6173. [CrossRef] [PubMed]
    • (2000) J. Immunol , vol.164 , pp. 6166-6173
    • Mills, C.D.1    Kincaid, K.2    Alt, J.M.3    Heilman, M.J.4    Hill, A.M.5
  • 75
    • 0034021278 scopus 로고    scopus 로고
    • Macrophage infiltration is associated with VEGF and EGFR expression in breast cancer
    • [CrossRef]
    • Leek, R. D.; Hunt, N. C.; Landers, R. J.; Lewis, C. E.; Royds, J. A.; Harris, A. L. Macrophage infiltration is associated with VEGF and EGFR expression in breast cancer. J. Pathol. 2000, 190, 430-436. [CrossRef]
    • (2000) J. Pathol , vol.190 , pp. 430-436
    • Leek, R.D.1    Hunt, N.C.2    Landers, R.J.3    Lewis, C.E.4    Royds, J.A.5    Harris, A.L.6
  • 76
    • 77951631347 scopus 로고    scopus 로고
    • Multiple roles of chemokine (C-C motif) ligand 2 in promoting prostate cancer growth
    • [CrossRef] [PubMed]
    • Zhang, J.; Lu, Y.; Pienta, K. J. Multiple roles of chemokine (C-C motif) ligand 2 in promoting prostate cancer growth. J. Natl. Cancer Inst. 2010, 102, 522-528. [CrossRef] [PubMed]
    • (2010) J. Natl. Cancer Inst , vol.102 , pp. 522-528
    • Zhang, J.1    Lu, Y.2    Pienta, K.J.3
  • 77
    • 0026112409 scopus 로고
    • Expression of arginase by mouse myeloid leukemic cell differentiation in vitro induced with tumor necrosis factor
    • [CrossRef] [PubMed]
    • Kosaka, T.; Kuwabara, M.; Endo, A.; Tamaguchi, H.; Koide, F. Expression of arginase by mouse myeloid leukemic cell differentiation in vitro induced with tumor necrosis factor. J. Vet. Med. Sci. 1991, 53, 53-57. [CrossRef] [PubMed]
    • (1991) J. Vet. Med. Sci , vol.53 , pp. 53-57
    • Kosaka, T.1    Kuwabara, M.2    Endo, A.3    Tamaguchi, H.4    Koide, F.5
  • 78
    • 0036735299 scopus 로고    scopus 로고
    • Macrophages as effector cells in interleukin 12-induced T cell-dependent tumor rejection
    • [PubMed]
    • Tsung, K.; Dolan, J. P.; Tsung, Y. L.; Norton, J. A. Macrophages as effector cells in interleukin 12-induced T cell-dependent tumor rejection. Cancer Res. 2002, 62, 5069-5075. [PubMed]
    • (2002) Cancer Res , vol.62 , pp. 5069-5075
    • Tsung, K.1    Dolan, J.P.2    Tsung, Y.L.3    Norton, J.A.4
  • 79
    • 0036105771 scopus 로고    scopus 로고
    • Tumors and inflammatory infiltrates: Friends or foes?
    • [CrossRef] [PubMed]
    • Brigati, C.; Noonan, D. M.; Albini, A.; Benelli, R. Tumors and inflammatory infiltrates: Friends or foes? Clin. Exp. Metastasis 2002, 19, 247-258. [CrossRef] [PubMed]
    • (2002) Clin. Exp. Metastasis , vol.19 , pp. 247-258
    • Brigati, C.1    Noonan, D.M.2    Albini, A.3    Benelli, R.4
  • 80
    • 0036187615 scopus 로고    scopus 로고
    • The role of tumour-associated macrophages in tumour progression: Implications for new anticancer therapies
    • [CrossRef] [PubMed]
    • Bingle, L.; Brown, N. J.; Lewis, C. E. The role of tumour-associated macrophages in tumour progression: Implications for new anticancer therapies. J. Pathol. 2002, 196, 254-265. [CrossRef] [PubMed]
    • (2002) J. Pathol , vol.196 , pp. 254-265
    • Bingle, L.1    Brown, N.J.2    Lewis, C.E.3
  • 81
    • 0005339099 scopus 로고    scopus 로고
    • Tumor-associated macrophages in breast cancer
    • [CrossRef] [PubMed]
    • Leek, R. D.; Harris, A. L. Tumor-associated macrophages in breast cancer. J. Mammary Gland Biol. Neoplasia 2002, 7, 177-189. [CrossRef] [PubMed]
    • (2002) J. Mammary Gland Biol. Neoplasia , vol.7 , pp. 177-189
    • Leek, R.D.1    Harris, A.L.2
  • 83
    • 84866307571 scopus 로고    scopus 로고
    • Cancer-stimulated mesenchymal stem cells create a carcinoma stem cell niche via prostaglandin E2 signaling
    • [CrossRef] [PubMed]
    • Li, H. J.; Reinhardt, F.; Herschman, H. R.; Weinberg, R. A. Cancer-stimulated mesenchymal stem cells create a carcinoma stem cell niche via prostaglandin E2 signaling. Cancer Discov. 2012, 2, 840-855. [CrossRef] [PubMed]
    • (2012) Cancer Discov , vol.2 , pp. 840-855
    • Li, H.J.1    Reinhardt, F.2    Herschman, H.R.3    Weinberg, R.A.4
  • 85
    • 0034650795 scopus 로고    scopus 로고
    • Macrophage infiltration correlates with tumor stage and angiogenesis in human malignant melanoma: Possible involvement of TNFα and IL-1α
    • [CrossRef]
    • Torisu, H.; Ono, M.; Kiryu, H.; Furue, M.; Ohmoto, Y.; Nakayama, J.; Nishioka, Y.; Sone, S.; Kuwano, M. Macrophage infiltration correlates with tumor stage and angiogenesis in human malignant melanoma: Possible involvement of TNFα and IL-1α. Int. J. Cancer 2000, 85, 182-188. [CrossRef]
    • (2000) Int. J. Cancer , vol.85 , pp. 182-188
    • Torisu, H.1    Ono, M.2    Kiryu, H.3    Furue, M.4    Ohmoto, Y.5    Nakayama, J.6    Nishioka, Y.7    Sone, S.8    Kuwano, M.9
  • 86
    • 84884907997 scopus 로고    scopus 로고
    • Use of mesenchymal stem cells (MSC) in chronic inflammatory fistulizing and fibrotic diseases: A comprehensive review
    • [CrossRef] [PubMed]
    • Voswinkel, J.; Francois, S.; Simon, J. M.; Benderitter, M.; Gorin, N. C.; Mohty, M.; Fouillard, L.; Chapel, A. Use of mesenchymal stem cells (MSC) in chronic inflammatory fistulizing and fibrotic diseases: A comprehensive review. Clin. Rev. Allergy Immunol. 2013, 45, 180-192. [CrossRef] [PubMed]
    • (2013) Clin. Rev. Allergy Immunol , vol.45 , pp. 180-192
    • Voswinkel, J.1    Francois, S.2    Simon, J.M.3    Benderitter, M.4    Gorin, N.C.5    Mohty, M.6    Fouillard, L.7    Chapel, A.8
  • 87
    • 77952502966 scopus 로고    scopus 로고
    • Interleukin-1 receptor antagonist (IL-1Ra) and IL-1Ra producing mesenchymal stem cells as modulators of diabetogenesis
    • [CrossRef] [PubMed]
    • Volarevic, V.; al-Qahtani, A.; Arsenijevic, N.; Pajovic, S.; Lukic, M. L. Interleukin-1 receptor antagonist (IL-1Ra) and IL-1Ra producing mesenchymal stem cells as modulators of diabetogenesis. Autoimmunity 2010, 43, 255-263. [CrossRef] [PubMed]
    • (2010) Autoimmunity , vol.43 , pp. 255-263
    • Volarevic, V.1    al-Qahtani, A.2    Arsenijevic, N.3    Pajovic, S.4    Lukic, M.L.5
  • 89
    • 58149326737 scopus 로고    scopus 로고
    • Bone marrow stromal cells attenuate sepsis via prostaglandin E2-dependent reprogramming of host macrophages to increase their interleukin-10 production
    • [CrossRef] [PubMed]
    • Nemeth, K.; Leelahavanichkul, A.; Yuen, P. S.; Mayer, B.; Parmelee, A.; Doi, K.; Robey, P. G.; Leelahavanichkul, K.; Koller, B. H.; Brown, J. M.; et al. Bone marrow stromal cells attenuate sepsis via prostaglandin E2-dependent reprogramming of host macrophages to increase their interleukin-10 production. Nat. Med. 2009, 15, 42-49. [CrossRef] [PubMed]
    • (2009) Nat. Med , vol.15 , pp. 42-49
    • Nemeth, K.1    Leelahavanichkul, A.2    Yuen, P.S.3    Mayer, B.4    Parmelee, A.5    Doi, K.6    Robey, P.G.7    Leelahavanichkul, K.8    Koller, B.H.9    Brown, J.M.10
  • 90
    • 69249227552 scopus 로고    scopus 로고
    • MSCs inhibit monocyte-derived DC maturation and function by selectively interfering with the generation of immature DCs: Central role of MSC-derived prostaglandin E2
    • [CrossRef] [PubMed]
    • Spaggiari, G. M.; Abdelrazik, H.; Becchetti, F.; Moretta, L. MSCs inhibit monocyte-derived DC maturation and function by selectively interfering with the generation of immature DCs: Central role of MSC-derived prostaglandin E2. Blood 2009, 113, 6576-6583. [CrossRef] [PubMed]
    • (2009) Blood , vol.113 , pp. 6576-6583
    • Spaggiari, G.M.1    Abdelrazik, H.2    Becchetti, F.3    Moretta, L.4
  • 91
    • 34547903606 scopus 로고    scopus 로고
    • Mesenchymal stem cells inhibit the differentiation of dendritic cells through an interleukin-6-dependent mechanism
    • [CrossRef] [PubMed]
    • Djouad, F.; Charbonnier, L. M.; Bouffi, C.; Louis-Plence, P.; Bony, C.; Apparailly, F.; Cantos, C.; Jorgensen, C.; Noel, D. Mesenchymal stem cells inhibit the differentiation of dendritic cells through an interleukin-6-dependent mechanism. Stem Cells 2007, 25, 2025-2032. [CrossRef] [PubMed]
    • (2007) Stem Cells , vol.25 , pp. 2025-2032
    • Djouad, F.1    Charbonnier, L.M.2    Bouffi, C.3    Louis-Plence, P.4    Bony, C.5    Apparailly, F.6    Cantos, C.7    Jorgensen, C.8    Noel, D.9
  • 92
    • 18544371666 scopus 로고    scopus 로고
    • Human mesenchymal stem cells inhibit differentiation and function of monocyte-derived dendritic cells
    • [CrossRef] [PubMed]
    • Jiang, X. X.; Zhang, Y.; Liu, B.; Zhang, S. X.; Wu, Y.; Yu, X. D.; Mao, N. Human mesenchymal stem cells inhibit differentiation and function of monocyte-derived dendritic cells. Blood 2005, 105, 4120-4126. [CrossRef] [PubMed]
    • (2005) Blood , vol.105 , pp. 4120-4126
    • Jiang, X.X.1    Zhang, Y.2    Liu, B.3    Zhang, S.X.4    Wu, Y.5    Yu, X.D.6    Mao, N.7
  • 93
    • 69249119079 scopus 로고    scopus 로고
    • Species variation in the mechanisms of mesenchymal stem cell-mediated immunosuppression
    • [CrossRef] [PubMed]
    • Ren, G.; Su, J.; Zhang, L.; Zhao, X.; Ling, W.; L'Huillie, A.; Zhang, J.; Lu, Y.; Roberts, A. I.; Ji, W.; et al. Species variation in the mechanisms of mesenchymal stem cell-mediated immunosuppression. Stem Cells 2009, 27, 1954-1962. [CrossRef] [PubMed]
    • (2009) Stem Cells , vol.27 , pp. 1954-1962
    • Ren, G.1    Su, J.2    Zhang, L.3    Zhao, X.4    Ling, W.5    L'Huillie, A.6    Zhang, J.7    Lu, Y.8    Roberts, A.I.9    Ji, W.10
  • 94
    • 33846006154 scopus 로고    scopus 로고
    • Nitric oxide plays a critical role in suppression of T-cell proliferation by mesenchymal stem cells
    • [CrossRef] [PubMed]
    • Sato, K.; Ozaki, K.; Oh, I.; Meguro, A.; Hatanaka, K.; Nagai, T.; Muroi, K.; Ozawa, K. Nitric oxide plays a critical role in suppression of T-cell proliferation by mesenchymal stem cells. Blood 2007, 109, 228-234. [CrossRef] [PubMed]
    • (2007) Blood , vol.109 , pp. 228-234
    • Sato, K.1    Ozaki, K.2    Oh, I.3    Meguro, A.4    Hatanaka, K.5    Nagai, T.6    Muroi, K.7    Ozawa, K.8
  • 96
    • 38649105374 scopus 로고    scopus 로고
    • Mesenchymal stem cell-mediated immunosuppression occurs via concerted action of chemokines and nitric oxide
    • [CrossRef] [PubMed]
    • Ren, G.; Zhang, L.; Zhao, X.; Xu, G.; Zhang, Y.; Roberts, A. I.; Zhao, R. C.; Shi, Y. Mesenchymal stem cell-mediated immunosuppression occurs via concerted action of chemokines and nitric oxide. Cell Stem Cell 2008, 2, 141-150. [CrossRef] [PubMed]
    • (2008) Cell Stem Cell , vol.2 , pp. 141-150
    • Ren, G.1    Zhang, L.2    Zhao, X.3    Xu, G.4    Zhang, Y.5    Roberts, A.I.6    Zhao, R.C.7    Shi, Y.8
  • 98
    • 4644295385 scopus 로고    scopus 로고
    • Adult bone marrow-derived cells recruited during angiogenesis comprise precursors for periendothelial vascular mural cells
    • [CrossRef] [PubMed]
    • Rajantie, I.; Ilmonen, M.; Alminaite, A.; Ozerdem, U.; Alitalo, K.; Salven, P. Adult bone marrow-derived cells recruited during angiogenesis comprise precursors for periendothelial vascular mural cells. Blood 2004, 104, 2084-2086. [CrossRef] [PubMed]
    • (2004) Blood , vol.104 , pp. 2084-2086
    • Rajantie, I.1    Ilmonen, M.2    Alminaite, A.3    Ozerdem, U.4    Alitalo, K.5    Salven, P.6
  • 99
    • 58149235124 scopus 로고    scopus 로고
    • Bone marrow multipotent mesenchymal stroma cells act as pericyte-like migratory vehicles in experimental gliomas
    • [CrossRef] [PubMed]
    • Bexell, D.; Gunnarsson, S.; Tormin, A.; Darabi, A.; Gisselsson, D.; Roybon, L.; Scheding, S.; Bengzon, J. Bone marrow multipotent mesenchymal stroma cells act as pericyte-like migratory vehicles in experimental gliomas. Mol. Ther. 2009, 17, 183-190. [CrossRef] [PubMed]
    • (2009) Mol. Ther , vol.17 , pp. 183-190
    • Bexell, D.1    Gunnarsson, S.2    Tormin, A.3    Darabi, A.4    Gisselsson, D.5    Roybon, L.6    Scheding, S.7    Bengzon, J.8
  • 100
    • 1642373909 scopus 로고    scopus 로고
    • Marrow-derived stromal cells express genes encoding a broad spectrum of arteriogenic cytokines and promote in vitro and in vivo arteriogenesis through paracrine mechanisms
    • [CrossRef] [PubMed]
    • Kinnaird, T.; Stabile, E.; Burnett, M. S.; Lee, C. W.; Barr, S.; Fuchs, S.; Epstein, S. E. Marrow-derived stromal cells express genes encoding a broad spectrum of arteriogenic cytokines and promote in vitro and in vivo arteriogenesis through paracrine mechanisms. Circ. Res. 2004, 94, 678-685. [CrossRef] [PubMed]
    • (2004) Circ. Res , vol.94 , pp. 678-685
    • Kinnaird, T.1    Stabile, E.2    Burnett, M.S.3    Lee, C.W.4    Barr, S.5    Fuchs, S.6    Epstein, S.E.7
  • 101
    • 77955462308 scopus 로고    scopus 로고
    • Differential effect of ischaemic preconditioning on mobilisation and recruitment of haematopoietic and mesenchymal stem cells in porcine myocardial ischaemia-reperfusion
    • [CrossRef] [PubMed]
    • Gyongyosi, M.; Posa, A.; Pavo, N.; Hemetsberger, R.; Kvakan, H.; Steiner-Boker, S.; Petrasi, Z.; Manczur, F.; Pavo, I. J.; Edes, I. F.; et al. Differential effect of ischaemic preconditioning on mobilisation and recruitment of haematopoietic and mesenchymal stem cells in porcine myocardial ischaemia-reperfusion. Thromb. Haemost. 2010, 104, 376-384. [CrossRef] [PubMed]
    • (2010) Thromb. Haemost , vol.104 , pp. 376-384
    • Gyongyosi, M.1    Posa, A.2    Pavo, N.3    Hemetsberger, R.4    Kvakan, H.5    Steiner-Boker, S.6    Petrasi, Z.7    Manczur, F.8    Pavo, I.J.9    Edes, I.F.10
  • 102
    • 33847713357 scopus 로고    scopus 로고
    • Hypoxia affects mesenchymal stromal cell osteogenic differentiation and angiogenic factor expression
    • [CrossRef] [PubMed]
    • Potier, E.; Ferreira, E.; Andriamanalijaona, R.; Pujol, J. P.; Oudina, K.; Logeart-Avramoglou, D.; Petite, H. Hypoxia affects mesenchymal stromal cell osteogenic differentiation and angiogenic factor expression. Bone 2007, 40, 1078-1087. [CrossRef] [PubMed]
    • (2007) Bone , vol.40 , pp. 1078-1087
    • Potier, E.1    Ferreira, E.2    Andriamanalijaona, R.3    Pujol, J.P.4    Oudina, K.5    Logeart-Avramoglou, D.6    Petite, H.7
  • 103
    • 34648839855 scopus 로고    scopus 로고
    • Angiopoietin1/Tie2 and VEGF/Flk1 induced by MSC treatment amplifies angiogenesis and vascular stabilization after stroke
    • [CrossRef] [PubMed]
    • Zacharek, A.; Chen, J.; Cui, X.; Li, A.; Li, Y.; Roberts, C.; Feng, Y.; Gao, Q.; Chopp, M. Angiopoietin1/Tie2 and VEGF/Flk1 induced by MSC treatment amplifies angiogenesis and vascular stabilization after stroke. J. Cereb. Blood Flow Metab. 2007, 27, 1684-1691. [CrossRef] [PubMed]
    • (2007) J. Cereb. Blood Flow Metab , vol.27 , pp. 1684-1691
    • Zacharek, A.1    Chen, J.2    Cui, X.3    Li, A.4    Li, Y.5    Roberts, C.6    Feng, Y.7    Gao, Q.8    Chopp, M.9
  • 104
    • 34250701074 scopus 로고    scopus 로고
    • Malignant gliomas actively recruit bone marrow stromal cells by secreting angiogenic cytokines
    • [CrossRef] [PubMed]
    • Birnbaum, T.; Roider, J.; Schankin, C. J.; Padovan, C. S.; Schichor, C.; Goldbrunner, R.; Straube, A. Malignant gliomas actively recruit bone marrow stromal cells by secreting angiogenic cytokines. J. Neurooncol. 2007, 83, 241-247. [CrossRef] [PubMed]
    • (2007) J. Neurooncol , vol.83 , pp. 241-247
    • Birnbaum, T.1    Roider, J.2    Schankin, C.J.3    Padovan, C.S.4    Schichor, C.5    Goldbrunner, R.6    Straube, A.7
  • 105
    • 82955193699 scopus 로고    scopus 로고
    • Glioblastoma-dependent differentiation and angiogenic potential of human mesenchymal stem cells in vitro
    • [CrossRef] [PubMed]
    • Birnbaum, T.; Hildebrandt, J.; Nuebling, G.; Sostak, P.; Straube, A. Glioblastoma-dependent differentiation and angiogenic potential of human mesenchymal stem cells in vitro. J. Neurooncol. 2011, 105, 57-65. [CrossRef] [PubMed]
    • (2011) J. Neurooncol , vol.105 , pp. 57-65
    • Birnbaum, T.1    Hildebrandt, J.2    Nuebling, G.3    Sostak, P.4    Straube, A.5
  • 106
    • 47149102903 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stem cells facilitate engineering of long-lasting functional vasculature
    • [CrossRef] [PubMed]
    • Au, P.; Tam, J.; Fukumura, D.; Jain, R. K. Bone marrow-derived mesenchymal stem cells facilitate engineering of long-lasting functional vasculature. Blood 2008, 111, 4551-4558. [CrossRef] [PubMed]
    • (2008) Blood , vol.111 , pp. 4551-4558
    • Au, P.1    Tam, J.2    Fukumura, D.3    Jain, R.K.4
  • 107
    • 0043172396 scopus 로고    scopus 로고
    • Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis
    • [CrossRef] [PubMed]
    • Grunert, S.; Jechlinger, M.; Beug, H. Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis. Nat. Rev. Mol. Cell Biol. 2003, 4, 657-665. [CrossRef] [PubMed]
    • (2003) Nat. Rev. Mol. Cell Biol , vol.4 , pp. 657-665
    • Grunert, S.1    Jechlinger, M.2    Beug, H.3
  • 109
    • 77951953778 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition: From molecular mechanisms, redox regulation to implications in human health and disease
    • [CrossRef] [PubMed]
    • Cannito, S.; Novo, E.; di Bonzo, L. V.; Busletta, C.; Colombatto, S.; Parola, M. Epithelial-mesenchymal transition: From molecular mechanisms, redox regulation to implications in human health and disease. Antioxid. Redox Signal. 2010, 12, 1383-1430. [CrossRef] [PubMed]
    • (2010) Antioxid. Redox Signal , vol.12 , pp. 1383-1430
    • Cannito, S.1    Novo, E.2    di Bonzo, L.V.3    Busletta, C.4    Colombatto, S.5    Parola, M.6
  • 110
    • 63049123066 scopus 로고    scopus 로고
    • Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits
    • [CrossRef] [PubMed]
    • Polyak, K.; Weinberg, R. A. Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits. Nat. Rev. Cancer 2009, 9, 265-273. [CrossRef] [PubMed]
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 265-273
    • Polyak, K.1    Weinberg, R.A.2
  • 111
    • 22244492306 scopus 로고    scopus 로고
    • Carcinoma invasion and metastasis: A role for epithelial-mesenchymal transition?
    • [CrossRef] [PubMed]
    • Thompson, E. W.; Newgreen, D. F.; Tarin, D. Carcinoma invasion and metastasis: A role for epithelial-mesenchymal transition? Cancer Res. 2005, 65, 5991-5995. [CrossRef] [PubMed]
    • (2005) Cancer Res , vol.65 , pp. 5991-5995
    • Thompson, E.W.1    Newgreen, D.F.2    Tarin, D.3
  • 112
    • 48649098427 scopus 로고    scopus 로고
    • Platelet-derived growth factor-D overexpression contributes to epithelial-mesenchymal transition of PC3 prostate cancer cells
    • [CrossRef] [PubMed]
    • Kong, D.; Wang, Z.; Sarkar, S. H.; Li, Y.; Banerjee, S.; Saliganan, A.; Kim, H. R.; Cher, M. L.; Sarkar, F. H. Platelet-derived growth factor-D overexpression contributes to epithelial-mesenchymal transition of PC3 prostate cancer cells. Stem Cells 2008, 26, 1425-1435. [CrossRef] [PubMed]
    • (2008) Stem Cells , vol.26 , pp. 1425-1435
    • Kong, D.1    Wang, Z.2    Sarkar, S.H.3    Li, Y.4    Banerjee, S.5    Saliganan, A.6    Kim, H.R.7    Cher, M.L.8    Sarkar, F.H.9
  • 113
    • 67650999875 scopus 로고    scopus 로고
    • The basics of epithelial-mesenchymal transition
    • [CrossRef] [PubMed]
    • Kalluri, R.; Weinberg, R. A. The basics of epithelial-mesenchymal transition. J. Clin. Investig. 2009, 119, 1420-1428. [CrossRef] [PubMed]
    • (2009) J. Clin. Investig , vol.119 , pp. 1420-1428
    • Kalluri, R.1    Weinberg, R.A.2
  • 114
    • 0036595629 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in tumour progression
    • [CrossRef] [PubMed]
    • Thiery, J. P. Epithelial-mesenchymal transitions in tumour progression. Nat. Rev. Cancer 2002, 2, 442-454. [CrossRef] [PubMed]
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 442-454
    • Thiery, J.P.1
  • 115
    • 34447272058 scopus 로고    scopus 로고
    • Mechanisms of metastasis: Epithelial-to-mesenchymal transition and contribution of tumor microenvironment
    • [CrossRef] [PubMed]
    • Tse, J. C.; Kalluri, R. Mechanisms of metastasis: Epithelial-to-mesenchymal transition and contribution of tumor microenvironment. J. Cell. Biochem. 2007, 101, 816-829. [CrossRef] [PubMed]
    • (2007) J. Cell. Biochem , vol.101 , pp. 816-829
    • Tse, J.C.1    Kalluri, R.2
  • 116
    • 78649320264 scopus 로고    scopus 로고
    • Potential role of mesenchymal stem cells (MSCs) in the breast tumour microenvironment: Stimulation of epithelial to mesenchymal transition (EMT)
    • [CrossRef] [PubMed]
    • Martin, F. T.; Dwyer, R. M.; Kelly, J.; Khan, S.; Murphy, J. M.; Curran, C.; Miller, N.; Hennessy, E.; Dockery, P.; Barry, F. P.; et al. Potential role of mesenchymal stem cells (MSCs) in the breast tumour microenvironment: Stimulation of epithelial to mesenchymal transition (EMT). Breast Cancer Res. Treat. 2010, 124, 317-326. [CrossRef] [PubMed]
    • (2010) Breast Cancer Res. Treat , vol.124 , pp. 317-326
    • Martin, F.T.1    Dwyer, R.M.2    Kelly, J.3    Khan, S.4    Murphy, J.M.5    Curran, C.6    Miller, N.7    Hennessy, E.8    Dockery, P.9    Barry, F.P.10
  • 117
    • 84931078368 scopus 로고    scopus 로고
    • Paracrine factors from adipose-mesenchymal stem cells enhance metastatic capacity through Wnt signaling pathway in a colon cancer cell co-culture model
    • [PubMed]
    • Chen, D.; Liu, S.; Ma, H.; Liang, X.; Ma, H.; Yan, X.; Yang, B.; Wei, J.; Liu, X. Paracrine factors from adipose-mesenchymal stem cells enhance metastatic capacity through Wnt signaling pathway in a colon cancer cell co-culture model. Cancer Cell Int. 2015, 15, 42. [PubMed]
    • (2015) Cancer Cell Int , vol.15 , pp. 42
    • Chen, D.1    Liu, S.2    Ma, H.3    Liang, X.4    Ma, H.5    Yan, X.6    Yang, B.7    Wei, J.8    Liu, X.9
  • 118
    • 84939522108 scopus 로고    scopus 로고
    • Leptin produced by obese adipose stromal/stem cells enhances proliferation and metastasis of estrogen receptor positive breast cancers
    • [CrossRef] [PubMed]
    • Strong, A. L.; Ohlstein, J. F.; Biagas, B. A.; Rhodes, L. V.; Pei, D. T.; Tucker, H. A.; Llamas, C.; Bowles, A. C.; Dutreil, M. F.; Zhang, S.; et al. Leptin produced by obese adipose stromal/stem cells enhances proliferation and metastasis of estrogen receptor positive breast cancers. Breast Cancer Res. 2015, 17, 112. [CrossRef] [PubMed]
    • (2015) Breast Cancer Res , vol.17 , pp. 112
    • Strong, A.L.1    Ohlstein, J.F.2    Biagas, B.A.3    Rhodes, L.V.4    Pei, D.T.5    Tucker, H.A.6    Llamas, C.7    Bowles, A.C.8    Dutreil, M.F.9    Zhang, S.10
  • 119
    • 84946485529 scopus 로고    scopus 로고
    • Tumorigenic hybrids between mesenchymal stem cells and gastric cancer cells enhanced cancer proliferation, migration and stemness
    • [CrossRef] [PubMed]
    • Xue, J.; Zhu, Y.; Sun, Z.; Ji, R.; Zhang, X.; Xu, W.; Yuan, X.; Zhang, B.; Yan, Y.; Yin, L.; et al. Tumorigenic hybrids between mesenchymal stem cells and gastric cancer cells enhanced cancer proliferation, migration and stemness. BMC Cancer 2015, 15, 793. [CrossRef] [PubMed]
    • (2015) BMC Cancer , vol.15 , pp. 793
    • Xue, J.1    Zhu, Y.2    Sun, Z.3    Ji, R.4    Zhang, X.5    Xu, W.6    Yuan, X.7    Zhang, B.8    Yan, Y.9    Yin, L.10
  • 123
    • 84895528244 scopus 로고    scopus 로고
    • EMT and acquisition of stem cell-like properties are involved in spontaneous formation of tumorigenic hybrids between lung cancer and bone marrow-derived mesenchymal stem cells
    • [CrossRef] [PubMed]
    • Xu, M. H.; Gao, X.; Luo, D.; Zhou, X. D.; Xiong, W.; Liu, G. X. EMT and acquisition of stem cell-like properties are involved in spontaneous formation of tumorigenic hybrids between lung cancer and bone marrow-derived mesenchymal stem cells. PLoS ONE 2014, 9. [CrossRef] [PubMed]
    • (2014) PLoS ONE , pp. 9
    • Xu, M.H.1    Gao, X.2    Luo, D.3    Zhou, X.D.4    Xiong, W.5    Liu, G.X.6
  • 124
    • 84903190875 scopus 로고    scopus 로고
    • Fusion of HepG2 cells with mesenchymal stem cells increases cancer associated and malignant properties: An in vivo metastasis model
    • [CrossRef] [PubMed]
    • Li, H.; Feng, Z.; Tsang, T. C.; Tang, T.; Jia, X.; He, X.; Pennington, M. E.; Badowski, M. S.; Liu, A. K.; Chen, D.; et al. Fusion of HepG2 cells with mesenchymal stem cells increases cancer associated and malignant properties: An in vivo metastasis model. Oncol. Rep. 2014, 32, 539-547. [CrossRef] [PubMed]
    • (2014) Oncol. Rep , vol.32 , pp. 539-547
    • Li, H.1    Feng, Z.2    Tsang, T.C.3    Tang, T.4    Jia, X.5    He, X.6    Pennington, M.E.7    Badowski, M.S.8    Liu, A.K.9    Chen, D.10
  • 126
    • 45549103691 scopus 로고    scopus 로고
    • Implications of the cancer stem-cell hypothesis for breast cancer prevention and therapy
    • [CrossRef] [PubMed]
    • Kakarala, M.; Wicha, M. S. Implications of the cancer stem-cell hypothesis for breast cancer prevention and therapy. J. Clin. Oncol. 2008, 26, 2813-2820. [CrossRef] [PubMed]
    • (2008) J. Clin. Oncol , vol.26 , pp. 2813-2820
    • Kakarala, M.1    Wicha, M.S.2
  • 128
    • 79961006281 scopus 로고    scopus 로고
    • Human ovarian carcinoma-associated mesenchymal stem cells regulate cancer stem cells and tumorigenesis via altered BMP production
    • [CrossRef] [PubMed]
    • McLean, K.; Gong, Y.; Choi, Y.; Deng, N.; Yang, K.; Bai, S.; Cabrera, L.; Keller, E.; McCauley, L.; Cho, K. R.; et al. Human ovarian carcinoma-associated mesenchymal stem cells regulate cancer stem cells and tumorigenesis via altered BMP production. J. Clin. Investig. 2011, 121, 3206-3219. [CrossRef] [PubMed]
    • (2011) J. Clin. Investig , vol.121 , pp. 3206-3219
    • McLean, K.1    Gong, Y.2    Choi, Y.3    Deng, N.4    Yang, K.5    Bai, S.6    Cabrera, L.7    Keller, E.8    McCauley, L.9    Cho, K.R.10
  • 129
    • 84455163065 scopus 로고    scopus 로고
    • Mesenchymal stem cells promote tumor engraftment and metastatic colonization in rat osteosarcoma model
    • [PubMed]
    • Tsukamoto, S.; Honoki, K.; Fujii, H.; Tohma, Y.; Kido, A.; Mori, T.; Tsujiuchi, T.; Tanaka, Y. Mesenchymal stem cells promote tumor engraftment and metastatic colonization in rat osteosarcoma model. Int. J. Oncol. 2012, 40, 163-169. [PubMed]
    • (2012) Int. J. Oncol , vol.40 , pp. 163-169
    • Tsukamoto, S.1    Honoki, K.2    Fujii, H.3    Tohma, Y.4    Kido, A.5    Mori, T.6    Tsujiuchi, T.7    Tanaka, Y.8
  • 131
    • 84879517225 scopus 로고    scopus 로고
    • One cell, multiple roles: Contribution of mesenchymal stem cells to tumor development in tumor microenvironment
    • [CrossRef] [PubMed]
    • Yang, X.; Hou, J.; Han, Z.; Wang, Y.; Hao, C.; Wei, L.; Shi, Y. One cell, multiple roles: Contribution of mesenchymal stem cells to tumor development in tumor microenvironment. Cell Biosci. 2013, 3, 5. [CrossRef] [PubMed]
    • (2013) Cell Biosci , vol.3 , pp. 5
    • Yang, X.1    Hou, J.2    Han, Z.3    Wang, Y.4    Hao, C.5    Wei, L.6    Shi, Y.7
  • 132
    • 84988613635 scopus 로고    scopus 로고
    • A review of therapeutic effects of mesenchymal stem cell secretions and induction of secretory modification by different culture methods
    • [CrossRef] [PubMed]
    • Madrigal, M.; Rao, K. S.; Riordan, N. H. A review of therapeutic effects of mesenchymal stem cell secretions and induction of secretory modification by different culture methods. J. Transl. Med. 2014, 12, 260. [CrossRef] [PubMed]
    • (2014) J. Transl. Med , vol.12 , pp. 260
    • Madrigal, M.1    Rao, K.S.2    Riordan, N.H.3
  • 133
    • 84877056819 scopus 로고    scopus 로고
    • Low oxygen tension maintains multipotency, whereas normoxia increases differentiation of mouse bone marrow stromal cells
    • [CrossRef] [PubMed]
    • Berniakovich, I.; Giorgio, M. Low oxygen tension maintains multipotency, whereas normoxia increases differentiation of mouse bone marrow stromal cells. Int. J. Mol. Sci. 2013, 14, 2119-2134. [CrossRef] [PubMed]
    • (2013) Int. J. Mol. Sci , vol.14 , pp. 2119-2134
    • Berniakovich, I.1    Giorgio, M.2
  • 134
    • 62649104172 scopus 로고    scopus 로고
    • Epigenetic reprogramming of IGF1 and leptin genes by serum deprivation in multipotential mesenchymal stromal cells
    • [CrossRef] [PubMed]
    • Sanchez, C.; Oskowitz, A.; Pochampally, R. R. Epigenetic reprogramming of IGF1 and leptin genes by serum deprivation in multipotential mesenchymal stromal cells. Stem Cells 2009, 27, 375-382. [CrossRef] [PubMed]
    • (2009) Stem Cells , vol.27 , pp. 375-382
    • Sanchez, C.1    Oskowitz, A.2    Pochampally, R.R.3
  • 135
    • 34548739439 scopus 로고    scopus 로고
    • Short-term exposure of multipotent stromal cells to low oxygen increases their expression of CX3CR1 and CXCR4 and their engraftment in vivo
    • [CrossRef] [PubMed]
    • Hung, S. C.; Pochampally, R. R.; Hsu, S. C.; Sanchez, C.; Chen, S. C.; Spees, J.; Prockop, D. J. Short-term exposure of multipotent stromal cells to low oxygen increases their expression of CX3CR1 and CXCR4 and their engraftment in vivo. PLoS ONE 2007, 2. [CrossRef] [PubMed]
    • (2007) PLoS ONE , pp. 2
    • Hung, S.C.1    Pochampally, R.R.2    Hsu, S.C.3    Sanchez, C.4    Chen, S.C.5    Spees, J.6    Prockop, D.J.7
  • 136
    • 34748845732 scopus 로고    scopus 로고
    • Angiogenic effects of human multipotent stromal cell conditioned medium activate the PI3K-Akt pathway in hypoxic endothelial cells to inhibit apoptosis, increase survival, and stimulate angiogenesis
    • [CrossRef] [PubMed]
    • Hung, S. C.; Pochampally, R. R.; Chen, S. C.; Hsu, S. C.; Prockop, D. J. Angiogenic effects of human multipotent stromal cell conditioned medium activate the PI3K-Akt pathway in hypoxic endothelial cells to inhibit apoptosis, increase survival, and stimulate angiogenesis. Stem Cells 2007, 25, 2363-2370. [CrossRef] [PubMed]
    • (2007) Stem Cells , vol.25 , pp. 2363-2370
    • Hung, S.C.1    Pochampally, R.R.2    Chen, S.C.3    Hsu, S.C.4    Prockop, D.J.5
  • 137
    • 78651422743 scopus 로고    scopus 로고
    • Angiogenic properties of aged adipose derived mesenchymal stem cells after hypoxic conditioning
    • [CrossRef] [PubMed]
    • Efimenko, A.; Starostina, E.; Kalinina, N.; Stolzing, A. Angiogenic properties of aged adipose derived mesenchymal stem cells after hypoxic conditioning. J. Transl. Med. 2011, 9, 10. [CrossRef] [PubMed]
    • (2011) J. Transl. Med , vol.9 , pp. 10
    • Efimenko, A.1    Starostina, E.2    Kalinina, N.3    Stolzing, A.4
  • 138
    • 84925543438 scopus 로고    scopus 로고
    • Adipose tissue-derived mesenchymal stem cells cultured at high cell density express brain-derived neurotrophic factor and exert neuroprotective effects in a 6-hydroxydopamine rat model of Parkinson's disease
    • [CrossRef]
    • Park, J. B.; Lee, J. S.; Cho, B. P.; Rhee, K. J.; Baik, S. K.; Kim, J.; Kang, S. J.; Park, D. J.; Oh, J. E.; Shin, H. C.; et al. Adipose tissue-derived mesenchymal stem cells cultured at high cell density express brain-derived neurotrophic factor and exert neuroprotective effects in a 6-hydroxydopamine rat model of Parkinson's disease. Genes Genom. 2015, 37, 213-221. [CrossRef]
    • (2015) Genes Genom , vol.37 , pp. 213-221
    • Park, J.B.1    Lee, J.S.2    Cho, B.P.3    Rhee, K.J.4    Baik, S.K.5    Kim, J.6    Kang, S.J.7    Park, D.J.8    Oh, J.E.9    Shin, H.C.10
  • 139
    • 0037085765 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF)-C signaling through FLT-4 (VEGFR-3) mediates leukemic cell proliferation, survival, and resistance to chemotherapy
    • [CrossRef] [PubMed]
    • Dias, S.; Choy, M.; Alitalo, K.; Rafii, S. Vascular endothelial growth factor (VEGF)-C signaling through FLT-4 (VEGFR-3) mediates leukemic cell proliferation, survival, and resistance to chemotherapy. Blood 2002, 99, 2179-2184. [CrossRef] [PubMed]
    • (2002) Blood , vol.99 , pp. 2179-2184
    • Dias, S.1    Choy, M.2    Alitalo, K.3    Rafii, S.4
  • 140
    • 0036530301 scopus 로고    scopus 로고
    • VEGF165 promotes survival of leukemic cells by Hsp90-mediated induction of Bcl-2 expression and apoptosis inhibition
    • [CrossRef] [PubMed]
    • Dias, S.; Shmelkov, S. V.; Lam, G.; Rafii, S. VEGF165 promotes survival of leukemic cells by Hsp90-mediated induction of Bcl-2 expression and apoptosis inhibition. Blood 2002, 99, 2532-2540. [CrossRef] [PubMed]
    • (2002) Blood , vol.99 , pp. 2532-2540
    • Dias, S.1    Shmelkov, S.V.2    Lam, G.3    Rafii, S.4
  • 141
    • 0031045135 scopus 로고    scopus 로고
    • Basic fibroblast growth factor (bFGF) upregulates the expression of bcl-2 in B cell chronic lymphocytic leukemia cell lines resulting in delaying apoptosis
    • [CrossRef] [PubMed]
    • Konig, A.; Menzel, T.; Lynen, S.; Wrazel, L.; Rosen, A.; al-Katib, A.; Raveche, E.; Gabrilove, J. L. Basic fibroblast growth factor (bFGF) upregulates the expression of bcl-2 in B cell chronic lymphocytic leukemia cell lines resulting in delaying apoptosis. Leukemia 1997, 11, 258-265. [CrossRef] [PubMed]
    • (1997) Leukemia , vol.11 , pp. 258-265
    • Konig, A.1    Menzel, T.2    Lynen, S.3    Wrazel, L.4    Rosen, A.5    al-Katib, A.6    Raveche, E.7    Gabrilove, J.L.8
  • 142
    • 0028100605 scopus 로고
    • Indirect angiogenic cytokines upregulate VEGF and bFGF gene expression in vascular smooth muscle cells, whereas hypoxia upregulates VEGF expression only
    • [CrossRef] [PubMed]
    • Brogi, E.; Wu, T.; Namiki, A.; Isner, J. M. Indirect angiogenic cytokines upregulate VEGF and bFGF gene expression in vascular smooth muscle cells, whereas hypoxia upregulates VEGF expression only. Circulation 1994, 90, 649-652. [CrossRef] [PubMed]
    • (1994) Circulation , vol.90 , pp. 649-652
    • Brogi, E.1    Wu, T.2    Namiki, A.3    Isner, J.M.4
  • 143
    • 0034667624 scopus 로고    scopus 로고
    • Blood-derived nurse-like cells protect chronic lymphocytic leukemia B cells from spontaneous apoptosis through stromal cell-derived factor-1
    • [PubMed]
    • Burger, J. A.; Tsukada, N.; Burger, M.; Zvaifler, N. J.; Dell'Aquila, M.; Kipps, T. J. Blood-derived nurse-like cells protect chronic lymphocytic leukemia B cells from spontaneous apoptosis through stromal cell-derived factor-1. Blood 2000, 96, 2655-2663. [PubMed]
    • (2000) Blood , vol.96 , pp. 2655-2663
    • Burger, J.A.1    Tsukada, N.2    Burger, M.3    Zvaifler, N.J.4    Dell'Aquila, M.5    Kipps, T.J.6
  • 144
    • 0242509783 scopus 로고    scopus 로고
    • Mesenchymal progenitor cell-mediated inhibition of tumor growth in vivo and in vitro in gelatin matrix
    • [CrossRef] [PubMed]
    • Ohlsson, L. B.; Varas, L.; Kjellman, C.; Edvardsen, K.; Lindvall, M. Mesenchymal progenitor cell-mediated inhibition of tumor growth in vivo and in vitro in gelatin matrix. Exp. Mol. Pathol. 2003, 75, 248-255. [CrossRef] [PubMed]
    • (2003) Exp. Mol. Pathol , vol.75 , pp. 248-255
    • Ohlsson, L.B.1    Varas, L.2    Kjellman, C.3    Edvardsen, K.4    Lindvall, M.5
  • 145
    • 42549148535 scopus 로고    scopus 로고
    • The growth inhibitory effect of mesenchymal stem cells on tumor cells in vitro and in vivo
    • [CrossRef] [PubMed]
    • Lu, Y. R.; Yuan, Y.; Wang, X. J.; Wei, L. L.; Chen, Y. N.; Cong, C.; Li, S. F.; Long, D.; Tan, W. D.; Mao, Y. Q.; et al. The growth inhibitory effect of mesenchymal stem cells on tumor cells in vitro and in vivo. Cancer Biol. Ther. 2008, 7, 245-251. [CrossRef] [PubMed]
    • (2008) Cancer Biol. Ther , vol.7 , pp. 245-251
    • Lu, Y.R.1    Yuan, Y.2    Wang, X.J.3    Wei, L.L.4    Chen, Y.N.5    Cong, C.6    Li, S.F.7    Long, D.8    Tan, W.D.9    Mao, Y.Q.10
  • 146
    • 84906059145 scopus 로고    scopus 로고
    • Adipose tissue-derived mesenchymal stem cells cultured at high density express IFN-β and suppress the growth of MCF-7 human breast cancer cells
    • [CrossRef] [PubMed]
    • Ryu, H.; Oh, J. E.; Rhee, K. J.; Baik, S. K.; Kim, J.; Kang, S. J.; Sohn, J. H.; Choi, E.; Shin, H. C.; Kim, Y. M.; et al. Adipose tissue-derived mesenchymal stem cells cultured at high density express IFN-β and suppress the growth of MCF-7 human breast cancer cells. Cancer Lett. 2014, 352, 220-227. [CrossRef] [PubMed]
    • (2014) Cancer Lett , vol.352 , pp. 220-227
    • Ryu, H.1    Oh, J.E.2    Rhee, K.J.3    Baik, S.K.4    Kim, J.5    Kang, S.J.6    Sohn, J.H.7    Choi, E.8    Shin, H.C.9    Kim, Y.M.10
  • 147
    • 84861471254 scopus 로고    scopus 로고
    • IFN-primed human bone marrow mesenchymal stem cells induce tumor cell apoptosis in vitro via tumor necrosis factor-related apoptosis-inducing ligand
    • [CrossRef] [PubMed]
    • Du, J.; Zhou, L.; Chen, X.; Yan, S.; Ke, M.; Lu, X.; Wang, Z.; Yu, W.; Xiang, A. P. IFN-primed human bone marrow mesenchymal stem cells induce tumor cell apoptosis in vitro via tumor necrosis factor-related apoptosis-inducing ligand. Int. J. Biochem. Cell Biol. 2012, 44, 1305-1314. [CrossRef] [PubMed]
    • (2012) Int. J. Biochem. Cell Biol , vol.44 , pp. 1305-1314
    • Du, J.1    Zhou, L.2    Chen, X.3    Yan, S.4    Ke, M.5    Lu, X.6    Wang, Z.7    Yu, W.8    Xiang, A.P.9
  • 148
    • 77955239592 scopus 로고    scopus 로고
    • Human bone marrow mesenchymal stem cells display anti-cancer activity in scid mice bearing disseminated non-Hodgkin's lymphoma xenografts
    • [CrossRef] [PubMed]
    • Secchiero, P.; Zorzet, S.; Tripodo, C.; Corallini, F.; Melloni, E.; Caruso, L.; Bosco, R.; Ingrao, S.; Zavan, B.; Zauli, G. Human bone marrow mesenchymal stem cells display anti-cancer activity in scid mice bearing disseminated non-Hodgkin's lymphoma xenografts. PLoS ONE 2010, 5. [CrossRef] [PubMed]
    • (2010) PLoS ONE , pp. 5
    • Secchiero, P.1    Zorzet, S.2    Tripodo, C.3    Corallini, F.4    Melloni, E.5    Caruso, L.6    Bosco, R.7    Ingrao, S.8    Zavan, B.9    Zauli, G.10
  • 149
    • 15944376184 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells induce division arrest anergy of activated T cells
    • [CrossRef] [PubMed]
    • Glennie, S.; Soeiro, I.; Dyson, P. J.; Lam, E. W.; Dazzi, F. Bone marrow mesenchymal stem cells induce division arrest anergy of activated T cells. Blood 2005, 105, 2821-2827. [CrossRef] [PubMed]
    • (2005) Blood , vol.105 , pp. 2821-2827
    • Glennie, S.1    Soeiro, I.2    Dyson, P.J.3    Lam, E.W.4    Dazzi, F.5
  • 150
    • 13544249606 scopus 로고    scopus 로고
    • Human mesenchymal stem cells modulate allogeneic immune cell responses
    • [CrossRef] [PubMed]
    • Aggarwal, S.; Pittenger, M. F. Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood 2005, 105, 1815-1822. [CrossRef] [PubMed]
    • (2005) Blood , vol.105 , pp. 1815-1822
    • Aggarwal, S.1    Pittenger, M.F.2
  • 152
    • 33645508766 scopus 로고    scopus 로고
    • Interactions between human mesenchymal stem cells and natural killer cells
    • [CrossRef] [PubMed]
    • Sotiropoulou, P. A.; Perez, S. A.; Gritzapis, A. D.; Baxevanis, C. N.; Papamichail, M. Interactions between human mesenchymal stem cells and natural killer cells. Stem Cells 2006, 24, 74-85. [CrossRef] [PubMed]
    • (2006) Stem Cells , vol.24 , pp. 74-85
    • Sotiropoulou, P.A.1    Perez, S.A.2    Gritzapis, A.D.3    Baxevanis, C.N.4    Papamichail, M.5
  • 153
    • 33846483151 scopus 로고    scopus 로고
    • Mesenchymal stem cells inhibit proliferation and apoptosis of tumor cells: Impact on in vivo tumor growth
    • [CrossRef] [PubMed]
    • Ramasamy, R.; Lam, E. W.; Soeiro, I.; Tisato, V.; Bonnet, D.; Dazzi, F. Mesenchymal stem cells inhibit proliferation and apoptosis of tumor cells: Impact on in vivo tumor growth. Leukemia 2007, 21, 304-310. [CrossRef] [PubMed]
    • (2007) Leukemia , vol.21 , pp. 304-310
    • Ramasamy, R.1    Lam, E.W.2    Soeiro, I.3    Tisato, V.4    Bonnet, D.5    Dazzi, F.6
  • 154
    • 33746257209 scopus 로고    scopus 로고
    • The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism
    • [CrossRef] [PubMed]
    • Engelman, J. A.; Luo, J.; Cantley, L. C. The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism. Nat. Rev. Genet. 2006, 7, 606-619. [CrossRef] [PubMed]
    • (2006) Nat. Rev. Genet , vol.7 , pp. 606-619
    • Engelman, J.A.1    Luo, J.2    Cantley, L.C.3
  • 155
    • 0037205048 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase pathway
    • [CrossRef] [PubMed]
    • Cantley, L. C. The phosphoinositide 3-kinase pathway. Science 2002, 296, 1655-1657. [CrossRef] [PubMed]
    • (2002) Science , vol.296 , pp. 1655-1657
    • Cantley, L.C.1
  • 156
    • 84865210598 scopus 로고    scopus 로고
    • Homeostasis and the importance for a balance between AKT/mTOR activity and intracellular signaling
    • [CrossRef] [PubMed]
    • Altomare, D. A.; Khaled, A. R. Homeostasis and the importance for a balance between AKT/mTOR activity and intracellular signaling. Curr. Med. Chem. 2012, 19, 3748-3762. [CrossRef] [PubMed]
    • (2012) Curr. Med. Chem , vol.19 , pp. 3748-3762
    • Altomare, D.A.1    Khaled, A.R.2
  • 157
    • 84860217431 scopus 로고    scopus 로고
    • The functions and regulation of the PTEN tumour suppressor
    • [CrossRef] [PubMed]
    • Song, M. S.; Salmena, L.; Pandolfi, P. P. The functions and regulation of the PTEN tumour suppressor. Nat. Rev. Mol. Cell Biol. 2012, 13, 283-296. [CrossRef] [PubMed]
    • (2012) Nat. Rev. Mol. Cell Biol , vol.13 , pp. 283-296
    • Song, M.S.1    Salmena, L.2    Pandolfi, P.P.3
  • 158
    • 67649814136 scopus 로고    scopus 로고
    • PI3K/PTEN signaling in angiogenesis and tumorigenesis
    • [CrossRef] [PubMed]
    • Jiang, B. H.; Liu, L. Z. PI3K/PTEN signaling in angiogenesis and tumorigenesis. Adv. Cancer Res. 2009, 102, 19-65. [CrossRef] [PubMed]
    • (2009) Adv. Cancer Res , vol.102 , pp. 19-65
    • Jiang, B.H.1    Liu, L.Z.2
  • 159
    • 59249091735 scopus 로고    scopus 로고
    • Evolution of the Wnt pathways
    • [PubMed]
    • Croce, J. C.; McClay, D. R. Evolution of the Wnt pathways. Methods Mol. Biol. 2008, 469, 3-18. [PubMed]
    • (2008) Methods Mol. Biol , vol.469 , pp. 3-18
    • Croce, J.C.1    McClay, D.R.2
  • 160
    • 0033895709 scopus 로고    scopus 로고
    • Wnt signaling and cancer
    • [CrossRef] [PubMed]
    • Polakis, P. Wnt signaling and cancer. Genes Dev. 2000, 14, 1837-1851. [CrossRef] [PubMed]
    • (2000) Genes Dev , vol.14 , pp. 1837-1851
    • Polakis, P.1
  • 161
    • 0038359353 scopus 로고    scopus 로고
    • Caught up in a wnt storm: Wnt signaling in cancer
    • [CrossRef]
    • Giles, R. H.; van Es, J. H.; Clevers, H. Caught up in a wnt storm: Wnt signaling in cancer. Biochim. Biophys. Acta 2003, 1653, 1-24. [CrossRef]
    • (2003) Biochim. Biophys. Acta , vol.1653 , pp. 1-24
    • Giles, R.H.1    van Es, J.H.2    Clevers, H.3
  • 162
    • 8444251784 scopus 로고    scopus 로고
    • The Wnt signaling pathway in development and disease
    • [CrossRef] [PubMed]
    • Logan, C. Y.; Nusse, R. The Wnt signaling pathway in development and disease. Annu. Rev. Cell Dev. Biol. 2004, 20, 781-810. [CrossRef] [PubMed]
    • (2004) Annu. Rev. Cell Dev. Biol , vol.20 , pp. 781-810
    • Logan, C.Y.1    Nusse, R.2
  • 164
    • 84930031124 scopus 로고    scopus 로고
    • β-Catenin signaling and roles in liver homeostasis, injury, and tumorigenesis
    • [CrossRef] [PubMed]
    • Monga, S. P. β-Catenin signaling and roles in liver homeostasis, injury, and tumorigenesis. Gastroenterology 2015, 148, 1294-1310. [CrossRef] [PubMed]
    • (2015) Gastroenterology , vol.148 , pp. 1294-1310
    • Monga, S.P.1
  • 165
    • 84944886259 scopus 로고    scopus 로고
    • Role of the Wnt/β-catenin pathway in gastric cancer: An in-depth literature review
    • [CrossRef] [PubMed]
    • Chiurillo, M. A. Role of the Wnt/β-catenin pathway in gastric cancer: An in-depth literature review. World J. Exp. Med. 2015, 5, 84-102. [CrossRef] [PubMed]
    • (2015) World J. Exp. Med , vol.5 , pp. 84-102
    • Chiurillo, M.A.1
  • 166
    • 79960857043 scopus 로고    scopus 로고
    • Key signaling nodes in mammary gland development and cancer: β-Catenin
    • [CrossRef] [PubMed]
    • Incassati, A.; Chandramouli, A.; Eelkema, R.; Cowin, P. Key signaling nodes in mammary gland development and cancer: β-Catenin. Breast Cancer Res. 2010, 12, 213. [CrossRef] [PubMed]
    • (2010) Breast Cancer Res , vol.12 , pp. 213
    • Incassati, A.1    Chandramouli, A.2    Eelkema, R.3    Cowin, P.4
  • 167
    • 78149500341 scopus 로고    scopus 로고
    • Wnt and mammary stem cells: Hormones cannot fly wingless
    • [CrossRef] [PubMed]
    • Roarty, K.; Rosen, J. M. Wnt and mammary stem cells: Hormones cannot fly wingless. Curr. Opin. Pharmacol. 2010, 10, 643-649. [CrossRef] [PubMed]
    • (2010) Curr. Opin. Pharmacol , vol.10 , pp. 643-649
    • Roarty, K.1    Rosen, J.M.2
  • 168
    • 84055222589 scopus 로고    scopus 로고
    • The wnt/β-catenin signaling pathway: A potential therapeutic target in the treatment of triple negative breast cancer
    • [CrossRef] [PubMed]
    • King, T. D.; Suto, M. J.; Li, Y. The wnt/β-catenin signaling pathway: A potential therapeutic target in the treatment of triple negative breast cancer. J. Cell. Biochem. 2012, 113, 13-18. [CrossRef] [PubMed]
    • (2012) J. Cell. Biochem , vol.113 , pp. 13-18
    • King, T.D.1    Suto, M.J.2    Li, Y.3
  • 169
    • 5444233462 scopus 로고    scopus 로고
    • APC dosage effects in tumorigenesis and stem cell differentiation
    • [CrossRef] [PubMed]
    • Gaspar, C.; Fodde, R. APC dosage effects in tumorigenesis and stem cell differentiation. Int. J. Dev. Biol. 2004, 48, 377-386. [CrossRef] [PubMed]
    • (2004) Int. J. Dev. Biol , vol.48 , pp. 377-386
    • Gaspar, C.1    Fodde, R.2
  • 170
    • 4444326415 scopus 로고    scopus 로고
    • Up-regulation of Wnt-1 and β-catenin production in patients with advanced metastatic prostate carcinoma: Potential pathogenetic and prognostic implications
    • [CrossRef] [PubMed]
    • Chen, G.; Shukeir, N.; Potti, A.; Sircar, K.; Aprikian, A.; Goltzman, D.; Rabbani, S. A. Up-regulation of Wnt-1 and β-catenin production in patients with advanced metastatic prostate carcinoma: Potential pathogenetic and prognostic implications. Cancer 2004, 101, 1345-1356. [CrossRef] [PubMed]
    • (2004) Cancer , vol.101 , pp. 1345-1356
    • Chen, G.1    Shukeir, N.2    Potti, A.3    Sircar, K.4    Aprikian, A.5    Goltzman, D.6    Rabbani, S.A.7
  • 171
    • 4344584730 scopus 로고    scopus 로고
    • WNT and β-catenin signalling: Diseases and therapies
    • [CrossRef] [PubMed]
    • Moon, R. T.; Kohn, A. D.; De Ferrari, G. V.; Kaykas, A. WNT and β-catenin signalling: Diseases and therapies. Nat. Rev. Genet. 2004, 5, 691-701. [CrossRef] [PubMed]
    • (2004) Nat. Rev. Genet , vol.5 , pp. 691-701
    • Moon, R.T.1    Kohn, A.D.2    De Ferrari, G.V.3    Kaykas, A.4
  • 172
    • 66249083525 scopus 로고    scopus 로고
    • Mesenchymal stem cell delivery of TRAIL can eliminate metastatic cancer
    • [CrossRef] [PubMed]
    • Loebinger, M. R.; Eddaoudi, A.; Davies, D.; Janes, S. M. Mesenchymal stem cell delivery of TRAIL can eliminate metastatic cancer. Cancer Res. 2009, 69, 4134-4142. [CrossRef] [PubMed]
    • (2009) Cancer Res , vol.69 , pp. 4134-4142
    • Loebinger, M.R.1    Eddaoudi, A.2    Davies, D.3    Janes, S.M.4
  • 174
    • 33846908513 scopus 로고    scopus 로고
    • Differential gene expression associated with migration of mesenchymal stem cells to conditioned medium from tumor cells or bone marrow cells
    • [CrossRef] [PubMed]
    • Menon, L. G.; Picinich, S.; Koneru, R.; Gao, H.; Lin, S. Y.; Koneru, M.; Mayer-Kuckuk, P.; Glod, J.; Banerjee, D. Differential gene expression associated with migration of mesenchymal stem cells to conditioned medium from tumor cells or bone marrow cells. Stem Cells 2007, 25, 520-528. [CrossRef] [PubMed]
    • (2007) Stem Cells , vol.25 , pp. 520-528
    • Menon, L.G.1    Picinich, S.2    Koneru, R.3    Gao, H.4    Lin, S.Y.5    Koneru, M.6    Mayer-Kuckuk, P.7    Glod, J.8    Banerjee, D.9
  • 175
    • 34547167177 scopus 로고    scopus 로고
    • Targeted delivery of CX3CL1 to multiple lung tumors by mesenchymal stem cells
    • [CrossRef] [PubMed]
    • Xin, H.; Kanehira, M.; Mizuguchi, H.; Hayakawa, T.; Kikuchi, T.; Nukiwa, T.; Saijo, Y. Targeted delivery of CX3CL1 to multiple lung tumors by mesenchymal stem cells. Stem Cells 2007, 25, 1618-1626. [CrossRef] [PubMed]
    • (2007) Stem Cells , vol.25 , pp. 1618-1626
    • Xin, H.1    Kanehira, M.2    Mizuguchi, H.3    Hayakawa, T.4    Kikuchi, T.5    Nukiwa, T.6    Saijo, Y.7
  • 176
    • 33645468259 scopus 로고    scopus 로고
    • Mesenchymal progenitor cells as cellular vehicles for delivery of oncolytic adenoviruses
    • [CrossRef] [PubMed]
    • Komarova, S.; Kawakami, Y.; Stoff-Khalili, M. A.; Curiel, D. T.; Pereboeva, L. Mesenchymal progenitor cells as cellular vehicles for delivery of oncolytic adenoviruses. Mol. Cancer Ther. 2006, 5, 755-766. [CrossRef] [PubMed]
    • (2006) Mol. Cancer Ther , vol.5 , pp. 755-766
    • Komarova, S.1    Kawakami, Y.2    Stoff-Khalili, M.A.3    Curiel, D.T.4    Pereboeva, L.5
  • 177
    • 16844372863 scopus 로고    scopus 로고
    • Mesenchymal progenitor cells localize within hematopoietic sites throughout ontogeny
    • [CrossRef] [PubMed]
    • Mendes, S. C.; Robin, C.; Dzierzak, E. Mesenchymal progenitor cells localize within hematopoietic sites throughout ontogeny. Development 2005, 132, 1127-1136. [CrossRef] [PubMed]
    • (2005) Development , vol.132 , pp. 1127-1136
    • Mendes, S.C.1    Robin, C.2    Dzierzak, E.3
  • 178
    • 22144491551 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells express a restricted set of functionally active chemokine receptors capable of promoting migration to pancreatic islets
    • [CrossRef] [PubMed]
    • Sordi, V.; Malosio, M. L.; Marchesi, F.; Mercalli, A.; Melzi, R.; Giordano, T.; Belmonte, N.; Ferrari, G.; Leone, B. E.; Bertuzzi, F.; et al. Bone marrow mesenchymal stem cells express a restricted set of functionally active chemokine receptors capable of promoting migration to pancreatic islets. Blood 2005, 106, 419-427. [CrossRef] [PubMed]
    • (2005) Blood , vol.106 , pp. 419-427
    • Sordi, V.1    Malosio, M.L.2    Marchesi, F.3    Mercalli, A.4    Melzi, R.5    Giordano, T.6    Belmonte, N.7    Ferrari, G.8    Leone, B.E.9    Bertuzzi, F.10
  • 179
    • 33847617021 scopus 로고    scopus 로고
    • From the laboratory bench to the patient's bedside: An update on clinical trials with mesenchymal stem cells
    • [CrossRef] [PubMed]
    • Giordano, A.; Galderisi, U.; Marino, I. R. From the laboratory bench to the patient's bedside: An update on clinical trials with mesenchymal stem cells. J. Cell. Physiol. 2007, 211, 27-35. [CrossRef] [PubMed]
    • (2007) J. Cell. Physiol , vol.211 , pp. 27-35
    • Giordano, A.1    Galderisi, U.2    Marino, I.R.3
  • 180
    • 84859609690 scopus 로고    scopus 로고
    • Human umbilical cord Wharton's jelly mesenchymal stem cells do not transform to tumor-associated fibroblasts in the presence of breast and ovarian cancer cells unlike bone marrow mesenchymal stem cells
    • [CrossRef] [PubMed]
    • Subramanian, A.; Shu-Uin, G.; Kae-Siang, N.; Gauthaman, K.; Biswas, A.; Choolani, M.; Bongso, A.; Chui-Yee, F. Human umbilical cord Wharton's jelly mesenchymal stem cells do not transform to tumor-associated fibroblasts in the presence of breast and ovarian cancer cells unlike bone marrow mesenchymal stem cells. J. Cell. Biochem. 2012, 113, 1886-1895. [CrossRef] [PubMed]
    • (2012) J. Cell. Biochem , vol.113 , pp. 1886-1895
    • Subramanian, A.1    Shu-Uin, G.2    Kae-Siang, N.3    Gauthaman, K.4    Biswas, A.5    Choolani, M.6    Bongso, A.7    Chui-Yee, F.8
  • 181
    • 79959730303 scopus 로고    scopus 로고
    • Human mesenchymal stem cells respond to native but not oxidized damage associated molecular pattern molecules from necrotic (tumor) material
    • [CrossRef] [PubMed]
    • Lotfi, R.; Eisenbacher, J.; Solgi, G.; Fuchs, K.; Yildiz, T.; Nienhaus, C.; Rojewski, M. T.; Schrezenmeier, H. Human mesenchymal stem cells respond to native but not oxidized damage associated molecular pattern molecules from necrotic (tumor) material. Eur. J. Immunol. 2011, 41, 2021-2028. [CrossRef] [PubMed]
    • (2011) Eur. J. Immunol , vol.41 , pp. 2021-2028
    • Lotfi, R.1    Eisenbacher, J.2    Solgi, G.3    Fuchs, K.4    Yildiz, T.5    Nienhaus, C.6    Rojewski, M.T.7    Schrezenmeier, H.8
  • 182
    • 0041431109 scopus 로고    scopus 로고
    • Systemic delivery of bone marrow-derived mesenchymal stem cells to the infarcted myocardium: Feasibility, cell migration, and body distribution
    • [CrossRef] [PubMed]
    • Barbash, I. M.; Chouraqui, P.; Baron, J.; Feinberg, M. S.; Etzion, S.; Tessone, A.; Miller, L.; Guetta, E.; Zipori, D.; Kedes, L. H.; et al. Systemic delivery of bone marrow-derived mesenchymal stem cells to the infarcted myocardium: Feasibility, cell migration, and body distribution. Circulation 2003, 108, 863-868. [CrossRef] [PubMed]
    • (2003) Circulation , vol.108 , pp. 863-868
    • Barbash, I.M.1    Chouraqui, P.2    Baron, J.3    Feinberg, M.S.4    Etzion, S.5    Tessone, A.6    Miller, L.7    Guetta, E.8    Zipori, D.9    Kedes, L.H.10
  • 184
    • 38549127166 scopus 로고    scopus 로고
    • Human mesenchymal stem cells as a two-edged sword in hepatic regenerative medicine: Engraftment and hepatocyte differentiation versus profibrogenic potential
    • [CrossRef] [PubMed]
    • Di Bonzo, L. V.; Ferrero, I.; Cravanzola, C.; Mareschi, K.; Rustichell, D.; Novo, E.; Sanavio, F.; Cannito, S.; Zamara, E.; Bertero, M.; et al. Human mesenchymal stem cells as a two-edged sword in hepatic regenerative medicine: Engraftment and hepatocyte differentiation versus profibrogenic potential. Gut 2008, 57, 223-231. [CrossRef] [PubMed]
    • (2008) Gut , vol.57 , pp. 223-231
    • Di Bonzo, L.V.1    Ferrero, I.2    Cravanzola, C.3    Mareschi, K.4    Rustichell, D.5    Novo, E.6    Sanavio, F.7    Cannito, S.8    Zamara, E.9    Bertero, M.10
  • 186
    • 84878568928 scopus 로고    scopus 로고
    • Cell size and velocity of injection are major determinants of the safety of intracarotid stem cell transplantation
    • [CrossRef] [PubMed]
    • Janowski, M.; Lyczek, A.; Engels, C.; Xu, J.; Lukomska, B.; Bulte, J. W.; Walczak, P. Cell size and velocity of injection are major determinants of the safety of intracarotid stem cell transplantation. J. Cereb. Blood Flow Metab. 2013, 33, 921-927. [CrossRef] [PubMed]
    • (2013) J. Cereb. Blood Flow Metab , vol.33 , pp. 921-927
    • Janowski, M.1    Lyczek, A.2    Engels, C.3    Xu, J.4    Lukomska, B.5    Bulte, J.W.6    Walczak, P.7
  • 188
    • 0036644833 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stem cells as vehicles for interferon-beta delivery into tumors
    • [PubMed]
    • Studeny, M.; Marini, F. C.; Champlin, R. E.; Zompetta, C.; Fidler, I. J.; Andreeff, M. Bone marrow-derived mesenchymal stem cells as vehicles for interferon-beta delivery into tumors. Cancer Res. 2002, 62, 3603-3608. [PubMed]
    • (2002) Cancer Res , vol.62 , pp. 3603-3608
    • Studeny, M.1    Marini, F.C.2    Champlin, R.E.3    Zompetta, C.4    Fidler, I.J.5    Andreeff, M.6
  • 189
    • 55049094527 scopus 로고    scopus 로고
    • Therapeutic potential of mesenchymal stem cells producing interferon-α in a mouse melanoma lung metastasis model
    • [CrossRef] [PubMed]
    • Ren, C.; Kumar, S.; Chanda, D.; Chen, J.; Mountz, J. D.; Ponnazhagan, S. Therapeutic potential of mesenchymal stem cells producing interferon-α in a mouse melanoma lung metastasis model. Stem Cells 2008, 26, 2332-2338. [CrossRef] [PubMed]
    • (2008) Stem Cells , vol.26 , pp. 2332-2338
    • Ren, C.1    Kumar, S.2    Chanda, D.3    Chen, J.4    Mountz, J.D.5    Ponnazhagan, S.6
  • 190
    • 54549092165 scopus 로고    scopus 로고
    • Cancer gene therapy using mesenchymal stem cells expressing interferon-β in a mouse prostate cancer lung metastasis model
    • [CrossRef] [PubMed]
    • Ren, C.; Kumar, S.; Chanda, D.; Kallman, L.; Chen, J.; Mountz, J. D.; Ponnazhagan, S. Cancer gene therapy using mesenchymal stem cells expressing interferon-β in a mouse prostate cancer lung metastasis model. Gene Ther. 2008, 15, 1446-1453. [CrossRef] [PubMed]
    • (2008) Gene Ther , vol.15 , pp. 1446-1453
    • Ren, C.1    Kumar, S.2    Chanda, D.3    Kallman, L.4    Chen, J.5    Mountz, J.D.6    Ponnazhagan, S.7
  • 191
    • 33845349814 scopus 로고    scopus 로고
    • Prophylaxis against carcinogenesis in three kinds of unestablished tumor models via IL12-gene-engineered MSCs
    • [CrossRef] [PubMed]
    • Chen, X. C.; Wang, R.; Zhao, X.; Wei, Y. Q.; Hu, M.; Wang, Y. S.; Zhang, X. W.; Zhang, R.; Zhang, L.; Yao, B.; et al. Prophylaxis against carcinogenesis in three kinds of unestablished tumor models via IL12-gene-engineered MSCs. Carcinogenesis 2006, 27, 2434-2441. [CrossRef] [PubMed]
    • (2006) Carcinogenesis , vol.27 , pp. 2434-2441
    • Chen, X.C.1    Wang, R.2    Zhao, X.3    Wei, Y.Q.4    Hu, M.5    Wang, Y.S.6    Zhang, X.W.7    Zhang, R.8    Zhang, L.9    Yao, B.10
  • 193
    • 41149159755 scopus 로고    scopus 로고
    • A tumor-selective biotherapy with prolonged impact on established metastases based on cytokine gene-engineered MSCs
    • [CrossRef] [PubMed]
    • Chen, X.; Lin, X.; Zhao, J.; Shi, W.; Zhang, H.; Wang, Y.; Kan, B.; Du, L.; Wang, B.; Wei, Y.; et al. A tumor-selective biotherapy with prolonged impact on established metastases based on cytokine gene-engineered MSCs. Mol. Ther. 2008, 16, 749-756. [CrossRef] [PubMed]
    • (2008) Mol. Ther , vol.16 , pp. 749-756
    • Chen, X.1    Lin, X.2    Zhao, J.3    Shi, W.4    Zhang, H.5    Wang, Y.6    Kan, B.7    Du, L.8    Wang, B.9    Wei, Y.10
  • 194
    • 77954084666 scopus 로고    scopus 로고
    • Mesenchymal stromal cells alone or expressing interferon-beta suppress pancreatic tumors in vivo, an effect countered by anti-inflammatory treatment
    • [CrossRef] [PubMed]
    • Kidd, S.; Caldwell, L.; Dietrich, M.; Samudio, I.; Spaeth, E. L.; Watson, K.; Shi, Y.; Abbruzzese, J.; Konopleva, M.; Andreeff, M.; et al. Mesenchymal stromal cells alone or expressing interferon-beta suppress pancreatic tumors in vivo, an effect countered by anti-inflammatory treatment. Cytotherapy 2010, 12, 615-625. [CrossRef] [PubMed]
    • (2010) Cytotherapy , vol.12 , pp. 615-625
    • Kidd, S.1    Caldwell, L.2    Dietrich, M.3    Samudio, I.4    Spaeth, E.L.5    Watson, K.6    Shi, Y.7    Abbruzzese, J.8    Konopleva, M.9    Andreeff, M.10
  • 195
    • 77649185403 scopus 로고    scopus 로고
    • Therapeutic potential of human mesenchymal stem cells producing IL-12 in a mouse xenograft model of renal cell carcinoma
    • [CrossRef] [PubMed]
    • Gao, P.; Ding, Q.; Wu, Z.; Jiang, H.; Fang, Z. Therapeutic potential of human mesenchymal stem cells producing IL-12 in a mouse xenograft model of renal cell carcinoma. Cancer Lett. 2010, 290, 157-166. [CrossRef] [PubMed]
    • (2010) Cancer Lett , vol.290 , pp. 157-166
    • Gao, P.1    Ding, Q.2    Wu, Z.3    Jiang, H.4    Fang, Z.5
  • 196
    • 34547543191 scopus 로고    scopus 로고
    • Human mesenchymal stem cells lack tumor tropism but enhance the antitumor activity of oncolytic adenoviruses in orthotopic lung and breast tumors
    • [CrossRef] [PubMed]
    • Hakkarainen, T.; Sarkioja, M.; Lehenkari, P.; Miettinen, S.; Ylikomi, T.; Suuronen, R.; Desmond, R. A.; Kanerva, A.; Hemminki, A. Human mesenchymal stem cells lack tumor tropism but enhance the antitumor activity of oncolytic adenoviruses in orthotopic lung and breast tumors. Hum. Gene Ther. 2007, 18, 627-641. [CrossRef] [PubMed]
    • (2007) Hum. Gene Ther , vol.18 , pp. 627-641
    • Hakkarainen, T.1    Sarkioja, M.2    Lehenkari, P.3    Miettinen, S.4    Ylikomi, T.5    Suuronen, R.6    Desmond, R.A.7    Kanerva, A.8    Hemminki, A.9
  • 198
    • 58149200539 scopus 로고    scopus 로고
    • Cytosine deaminase expressing human mesenchymal stem cells mediated tumour regression in melanoma bearing mice
    • [CrossRef] [PubMed]
    • Kucerova, L.; Matuskova, M.; Pastorakova, A.; Tyciakova, S.; Jakubikova, J.; Bohovic, R.; Altanerova, V.; Altaner, C. Cytosine deaminase expressing human mesenchymal stem cells mediated tumour regression in melanoma bearing mice. J. Gene Med. 2008, 10, 1071-1082. [CrossRef] [PubMed]
    • (2008) J. Gene Med , vol.10 , pp. 1071-1082
    • Kucerova, L.1    Matuskova, M.2    Pastorakova, A.3    Tyciakova, S.4    Jakubikova, J.5    Bohovic, R.6    Altanerova, V.7    Altaner, C.8
  • 199
    • 34447132890 scopus 로고    scopus 로고
    • Adipose tissue-derived human mesenchymal stem cells mediated prodrug cancer gene therapy
    • [CrossRef] [PubMed]
    • Kucerova, L.; Altanerova, V.; Matuskova, M.; Tyciakova, S.; Altaner, C. Adipose tissue-derived human mesenchymal stem cells mediated prodrug cancer gene therapy. Cancer Res. 2007, 67, 6304-6313. [CrossRef] [PubMed]
    • (2007) Cancer Res , vol.67 , pp. 6304-6313
    • Kucerova, L.1    Altanerova, V.2    Matuskova, M.3    Tyciakova, S.4    Altaner, C.5
  • 200
    • 80053332286 scopus 로고    scopus 로고
    • Silica nanorattle-doxorubicin-anchored mesenchymal stem cells for tumor-tropic therapy
    • [CrossRef] [PubMed]
    • Li, L.; Guan, Y.; Liu, H.; Hao, N.; Liu, T.; Meng, X.; Fu, C.; Li, Y.; Qu, Q.; Zhang, Y.; et al. Silica nanorattle-doxorubicin-anchored mesenchymal stem cells for tumor-tropic therapy. ACS Nano 2011, 5, 7462-7470. [CrossRef] [PubMed]
    • (2011) ACS Nano , vol.5 , pp. 7462-7470
    • Li, L.1    Guan, Y.2    Liu, H.3    Hao, N.4    Liu, T.5    Meng, X.6    Fu, C.7    Li, Y.8    Qu, Q.9    Zhang, Y.10
  • 201
    • 6944247634 scopus 로고    scopus 로고
    • Tissue distribution, stability, and pharmacokinetics of APO2 ligand/tumor necrosis factor-related apoptosis-inducing ligand in human colon carcinoma COLO205 tumor-bearing nude mice
    • [CrossRef] [PubMed]
    • Xiang, H.; Nguyen, C. B.; Kelley, S. K.; Dybdal, N.; Escandon, E. Tissue distribution, stability, and pharmacokinetics of APO2 ligand/tumor necrosis factor-related apoptosis-inducing ligand in human colon carcinoma COLO205 tumor-bearing nude mice. Drug Metab. Dispos. 2004, 32, 1230-1238. [CrossRef] [PubMed]
    • (2004) Drug Metab. Dispos , vol.32 , pp. 1230-1238
    • Xiang, H.1    Nguyen, C.B.2    Kelley, S.K.3    Dybdal, N.4    Escandon, E.5
  • 202
    • 70349849517 scopus 로고    scopus 로고
    • Human bone marrow-derived mesenchymal stromal cells expressing S-TRAIL as a cellular delivery vehicle for human glioma therapy
    • [CrossRef] [PubMed]
    • Menon, L. G.; Kelly, K.; Yang, H. W.; Kim, S. K.; Black, P. M.; Carroll, R. S. Human bone marrow-derived mesenchymal stromal cells expressing S-TRAIL as a cellular delivery vehicle for human glioma therapy. Stem Cells 2009, 27, 2320-2330. [CrossRef] [PubMed]
    • (2009) Stem Cells , vol.27 , pp. 2320-2330
    • Menon, L.G.1    Kelly, K.2    Yang, H.W.3    Kim, S.K.4    Black, P.M.5    Carroll, R.S.6
  • 203
    • 16544369419 scopus 로고    scopus 로고
    • Marrow stromal cells for interleukin-2 delivery in cancer immunotherapy
    • [CrossRef] [PubMed]
    • Stagg, J.; Lejeune, L.; Paquin, A.; Galipeau, J. Marrow stromal cells for interleukin-2 delivery in cancer immunotherapy. Hum. Gene Ther. 2004, 15, 597-608. [CrossRef] [PubMed]
    • (2004) Hum. Gene Ther , vol.15 , pp. 597-608
    • Stagg, J.1    Lejeune, L.2    Paquin, A.3    Galipeau, J.4
  • 204
    • 49649128473 scopus 로고    scopus 로고
    • Neo-organoid of marrow mesenchymal stromal cells secreting interleukin-12 for breast cancer therapy
    • [CrossRef] [PubMed]
    • Eliopoulos, N.; Francois, M.; Boivin, M. N.; Martineau, D.; Galipeau, J. Neo-organoid of marrow mesenchymal stromal cells secreting interleukin-12 for breast cancer therapy. Cancer Res. 2008, 68, 4810-4818. [CrossRef] [PubMed]
    • (2008) Cancer Res , vol.68 , pp. 4810-4818
    • Eliopoulos, N.1    Francois, M.2    Boivin, M.N.3    Martineau, D.4    Galipeau, J.5
  • 205
    • 77949659742 scopus 로고    scopus 로고
    • Reduction of nontarget infection and systemic toxicity by targeted delivery of conditionally replicating viruses transported in mesenchymal stem cells
    • [CrossRef] [PubMed]
    • Dembinski, J. L.; Spaeth, E. L.; Fueyo, J.; Gomez-Manzano, C.; Studeny, M.; Andreeff, M.; Marini, F. C. Reduction of nontarget infection and systemic toxicity by targeted delivery of conditionally replicating viruses transported in mesenchymal stem cells. Cancer Gene Ther. 2010, 17, 289-297. [CrossRef] [PubMed]
    • (2010) Cancer Gene Ther , vol.17 , pp. 289-297
    • Dembinski, J.L.1    Spaeth, E.L.2    Fueyo, J.3    Gomez-Manzano, C.4    Studeny, M.5    Andreeff, M.6    Marini, F.C.7
  • 206
    • 67651011690 scopus 로고    scopus 로고
    • Retroviral vector-producing mesenchymal stem cells for targeted suicide cancer gene therapy
    • [CrossRef] [PubMed]
    • Uchibori, R.; Okada, T.; Ito, T.; Urabe, M.; Mizukami, H.; Kume, A.; Ozawa, K. Retroviral vector-producing mesenchymal stem cells for targeted suicide cancer gene therapy. J. Gene Med. 2009, 11, 373-381. [CrossRef] [PubMed]
    • (2009) J. Gene Med , vol.11 , pp. 373-381
    • Uchibori, R.1    Okada, T.2    Ito, T.3    Urabe, M.4    Mizukami, H.5    Kume, A.6    Ozawa, K.7
  • 207
    • 77249122967 scopus 로고    scopus 로고
    • HSV-tk expressing mesenchymal stem cells exert bystander effect on human glioblastoma cells
    • [CrossRef] [PubMed]
    • Matuskova, M.; Hlubinova, K.; Pastorakova, A.; Hunakova, L.; Altanerova, V.; Altaner, C.; Kucerova, L. HSV-tk expressing mesenchymal stem cells exert bystander effect on human glioblastoma cells. Cancer Lett. 2010, 290, 58-67. [CrossRef] [PubMed]
    • (2010) Cancer Lett , vol.290 , pp. 58-67
    • Matuskova, M.1    Hlubinova, K.2    Pastorakova, A.3    Hunakova, L.4    Altanerova, V.5    Altaner, C.6    Kucerova, L.7
  • 208
    • 70449429426 scopus 로고    scopus 로고
    • Targeting tumor stroma using engineered mesenchymal stem cells reduces the growth of pancreatic carcinoma
    • [CrossRef] [PubMed]
    • Zischek, C.; Niess, H.; Ischenko, I.; Conrad, C.; Huss, R.; Jauch, K. W.; Nelson, P. J.; Bruns, C. Targeting tumor stroma using engineered mesenchymal stem cells reduces the growth of pancreatic carcinoma. Ann. Surg. 2009, 250, 747-753. [CrossRef] [PubMed]
    • (2009) Ann. Surg , vol.250 , pp. 747-753
    • Zischek, C.1    Niess, H.2    Ischenko, I.3    Conrad, C.4    Huss, R.5    Jauch, K.W.6    Nelson, P.J.7    Bruns, C.8
  • 210
    • 84945914046 scopus 로고    scopus 로고
    • Therapeutic effects of mesenchymal stem cells for patients with chronic liver diseases: Systematic review and meta-analysis
    • [CrossRef] [PubMed]
    • Kim, G.; Eom, Y. W.; Baik, S. K.; Shin, Y.; Lim, Y. L.; Kim, M. Y.; Kwon, S. O.; Chang, S. J. Therapeutic effects of mesenchymal stem cells for patients with chronic liver diseases: Systematic review and meta-analysis. J. Korean Med. Sci. 2015, 30, 1405-1415. [CrossRef] [PubMed]
    • (2015) J. Korean Med. Sci , vol.30 , pp. 1405-1415
    • Kim, G.1    Eom, Y.W.2    Baik, S.K.3    Shin, Y.4    Lim, Y.L.5    Kim, M.Y.6    Kwon, S.O.7    Chang, S.J.8


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