Expression profiling of epithelial plasticity in tumor progression

Oncogene

Volumn 22, Issue 46, 2003, Pages 7155-7169

  Jechlinger, Martin ^a,d   Grunert, Stefan ^a   Tamir, Ido H ^a   Janda, Elzbieta ^a,e   Lüdemann, Susanna ^a,f   Waerner, Thomas ^a   Seither, Peter ^b   Weith, Andreas ^b   Beug, Hartmut ^a   Kraut, Norbert ^b,c  

^a RESEARCH INSTITUTE OF MOLECULAR PATHOLOGY   (Austria)

^b BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

^c BOEHRINGER INGELHEIM RCV GMBH AND CO KG   (Austria)

^d MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^e EUROPEAN PATENT OFFICE   (Germany)

^f UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

Author keywords

Epithelial mesenchymal transition; Microarray; Ras; TGF

Indexed keywords

CADHERIN; CATHEPSIN B; COLLAGEN TYPE 3; COLLAGEN TYPE 6; COLLAGENASE 3; DECORIN; DNA; ENZYME; GELATINASE A; GROWTH FACTOR; INTERFERON; LAMININ 1; MACROPHAGE ELASTASE; MEMBRANE PROTEIN; MEMBRANE RECEPTOR; NERVE CELL ADHESION MOLECULE; OSTEONECTIN; PERLECAN; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEINASE; PROTEINASE INHIBITOR; RNA; SYNDECAN 1; TENASCIN; TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR BETA; VIMENTIN;

ANIMAL CELL; ARTICLE; BREAST EPITHELIUM; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; CYTOSKELETON; DNA MICROARRAY; EPITHELIUM CELL; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION; MESENCHYME CELL; METASTASIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; ONCOGENE; ONCOGENE RAS; PRIORITY JOURNAL; UNINDEXED SEQUENCE; WESTERN BLOTTING;

ANIMALS; BREAST NEOPLASMS; CELL DIFFERENTIATION; CELL LINE; CELL TRANSFORMATION, NEOPLASTIC; CLUSTER ANALYSIS; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, RAS; HUMANS; MAMMARY GLANDS, ANIMAL; MESODERM; MICE; NEOPLASM INVASIVENESS; POLYRIBOSOMES; PROTEIN BIOSYNTHESIS; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

ANIMALIA;

EID: 0242720727     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1206887     Document Type: Article

References (50)

1. Anderson NL and Anderson NG. (1998). Electrophoresis, 19, 1853-1861.
2. Arthur HM, Ure J, Smith AJ, Renforth G, Wilson DI, Torsney E, Charlton R, Parums DV, Jowett T, Marchuk DA, Burn J and Diamond AG. (2000). Dev. Biol., 217, 42-53.
3. Berquin IM and Sloane BF. (1996). Adv. Exp. Med. Biol., 389, 281-294.
4. Boyer B, Valles AM and Edme N. (2000). Biochem. Pharmacol., 60, 1091-1099.
5. Brabletz T, Jung A, Reu S, Porzner M, Hlubek F, Kunz-Schughart LA, Knuechel R and Kirchner T. (2001). Proc. Natl. Acad. Sci. USA, 98, 10356-10361.
6. Cano A, Perez-Moreno MA, Rodrigo I, Locascio A, Blanco MJ, del Barrio MG, Portillo F and Nieto MA. (2000). Nat. Cell Biol., 2, 76-83.
7. Carballo E, Lai WS and Blackshear PJ. (1998). Science, 281, 1001-1005.
8. Christofori G and Semb H. (1999). Trends Biochem. Sci., 24, 73-76.
9. Damm K, Hemmann U, Garin-Chesa P, Hauel N, Kauffmann I, Priepke H, Niestroj C, Daiber C, Enenkel B, Guilliard B, Kraut N and Rettig W. (2001). EMBO J., 20, 6958-6968.
10. D'Arcangelo G, Homayouni R, Keshvara L, Rice DS, Sheldon M and Curran T. (1999). Neuron, 24, 471-479.
11. de Jong JS, van Diest PJ, van der Valk P and Baak JP. (1998). J. Pathol., 184, 44-52.
12. Downward J. (1998). Curr. Opin. Cell Biol., 10, 262-267.
13. Eger A, Stockinger A, Schaffhauser B, Beug H and Foisner R. (2000). J. Cell Biol., 148, 173-188.
14. Fambrough D, McClure K, Kazlauskas A. and Lander ES. (1999). Cell, 97, 727-741.
15. Gotzmann J, Huber H, Thallinger C, Wolschek M, Jansen B, Sculte-Hermann R, Beug H and Mikulits W. (2002). J. Cell Sci., 115, 1189-1202.
16. Grünert S, Jechlinger M and Beug Hec. (2003). Nat. Rev. Mol. Cell Biol., 4, 657-665.
17. Hanahan D and Weinberg RA. (2000). Cell, 100, 57-70.
18. Hay ED. (1995). Acta Anat., 154, 8-20.
19. Hocevar BA, Smine A, Xu XX and Howe PH. (2001). EMBO J., 20, 2789-2801.
20. Janda E, Lehmann K, Killisch I, Jechlinger M, Herzig M, Downward J, Beug H and Grunert S. (2002a). J. Cell Biol., 156, 299-313.
21. Janda E, Litos G, Grunert S, Downward J and Beug H. (2002b). Oncogene, 21, 5148-5159.
22. Kiemer AK, Takeuchi K and Quinlan MP. (2001). Oncogene, 20, 6679-6688.
23. Kumar S, Ghellal A, Li C, Byrne G, Haboubi N, Wang JM and Bundred N. (1999). Cancer Res., 59, 856-861.
24. Lehmann K, Janda E, Pierreux CE, Rytömaa M, Schulze A, McMahon M, Hill CS, Beug H and Downward J. (2000). Genes Dev., 14, 2610-2622.
25. Lockhart DJ, Dong H, Byrne MC, Follettie MT, Gallo MV, Chee MS, Mittmann M, Wang C, Kobayashi M, Horton H and Brown EL. (1996). Nat. Biotechnol., 14, 1675-1680.
26. Mikulits W, Pradet-Balade B, Habermann B, Beug H, Garcia-Sanz JA and Mullner EW. (2000). FASEB J., 14, 1641-1652.
27. Muraoka RS, Dumont N, Ritter CA, Dugger TC, Brantley DM, Chen J, Easterly E, Roebuck LR, Ryan S, Gotwals PJ, Koteliansky V and Arteaga CL. (2002). J. Clin. Invest., 109, 1551-1559.
28. Murthy A, Gonzalez-Agosti C, Cordero E, Pinney D, Candia C, Solomon F, Gusella J and Ramesh V. (1998). J. Biol. Chem., 273, 1273-1276.
29. Nieto MA, Sargent MG, Wilkinson DG and Cooke J. (1994). Science, 264, 835-839.
30. Oft M, Heider KH and Beug H. (1998). Curr. Biol., 8, 1243-1252.
31. Oft M, Peli J, Rudaz C, Schwarz H, Beug H and Reichmann E. (1996). Genes Dev., 10, 2462-2477.
32. Perou CM, Jeffrey SS, van de Rijn M, Rees CA, Eisen MB, Ross DT, Pergamenschikov A, Williams CF, Zhu SX, Lee JC, Lashkari D, Shalon D, Brown PO and Botstein D. (1999). Proc. Natl. Acad. Sci. USA, 96, 9212-9217.
33. Perou CM, Sorlie T, Eisen MB, van de Rijn M, Jeffrey SS, Rees CA, Pollack JR, Ross DT, Johnsen H, Akslen LA, Fluge O, Pergamenschikov A, Williams C, Zhu SX, Lonning PE, Borresen-Dale AL, Brown PO and Botstein D. (2000). Nature, 406, 747-752.
34. Petersen OW, Nielsen HL, Gudjonsson T, Villadsen R, Rank F, Niebuhr E, Bissell MJ and Ronnov-Jessen L. (2003). Am. J. Pathol., 162, 391-402.
35. Reichmann E, Schwarz H, Deiner EM, Leitner I, Eilers M, Busslinger M and Beug H. (1992). Cell, 71, 1103-1116.
36. Rodriguez-Viciana P, Warne PH, Khwaja A, Marte BM, Pappin D, Das P, Waterfield MD, Ridley A and Downward J. (1997). Cell, 89, 457-467.
37. Ross DT, Scherf U, Eisen MB, Perou CM, Rees C, Spellman P, Iyer V, Jeffrey SS, Van de Rijn M, Waltham M, Pergamenschikov A, Lee JC, Lashkari D, Shalon D, Myers TG, Weinstein JN, Botstein D and Brown PO. (2000). Nat. Genet., 24, 227-235.
38. Sager R. (1997). Proc. Natl. Acad. Sci. USA, 94, 952-955.
39. Schulze A, Lehmann K, Jefferies HB, McMahon M and Downward J. (2001). Genes Dev., 15, 981-994.
40. Thiery JP. (2002). Nat. Rev. Cancer, 2, 442-454.
41. Trommsdorff M, Gotthardt M, Hiesberger T, Shelton J, Stockinger W, Nimpf J, Hammer RE, Richardson JA and Herz J. (1999). Cell, 97, 689-701.
42. Tsujii M, Kawano S, Tsuji S, Sawaoka H, Hori M and DuBois RN. (1998). Cell, 93, 705-716.
43. van 't Veer LJ, Dai H, van de Vijver MJ, He YD, Hart AA, Mao M, Peterse HL, van der Kooy K, Marton MJ, Witteveen AT, Schreiber GJ, Kerkhoven RM, Roberts C, Linsley PS, Bernards R and Friend SH. (2002). Nature, 415, 530-536.
44. Vignais ML and Gilman M. (1999). Mol. Cell Biol., 19, 3727-3735.
45. Webb DJ, Nguyen DH, Sankovic M and Gohia SL. (1999). J. Biol. Chem., 274, 7412-7420.
46. Yang YA, Dukhanina O, Tang B, Mamura M, Letterio JJ, MacGregor J, Patel SC, Khozin S, Liu ZY, Green J, Anver MR, Merlino G and Wakefield LM. (2002). J. Clin. Invest., 109, 1607-1615.
47. Zavadil J, Bitzer M, Liang D, Yang YC, Massimi A, Kneitz S, Piek E and Bottinger EP. (2001). Proc. Natl. Acad. Sci. USA, 98, 6686-6691.
48. Zhang H, Reynaud S, Kloc M, Etkin LD and Spohr G. (1995). Mech. Dev., 50, 119-130.
49. Zhou J and Hsieh JT. (2001). J. Biol. Chem., 276, 27793-27798.
50. Zong Q, Schummer M, Hood L and Morris DR. (1999). Proc. Natl. Acad. Sci. USA, 96, 10632-10636.