Leptin produced by obese adipose stromal/stem cells enhances proliferation and metastasis of estrogen receptor positive breast cancers

Breast Cancer Research

Volumn 17, Issue 1, 2015, Pages

  Strong, Amy L ^a   Ohlstein, Jason F ^a   Biagas, Brandi A ^a   Rhodes, Lyndsay V ^b   Pei, Dorothy T ^a   Tucker, H Alan ^a   Llamas, Claire ^a   Bowles, Annie C ^a   Dutreil, Maria F ^a   Zhang, Shijia ^a   Gimble, Jeffrey M ^a,b   Burow, Matthew E ^b   Bunnell, Bruce A ^a  

^a TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TULANE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATASE; GELATINASE A; INTERLEUKIN 6; LEPTIN; ESTROGEN RECEPTOR; PLASMINOGEN ACTIVATOR INHIBITOR 1; SERPINE1 PROTEIN, HUMAN; SMALL INTERFERING RNA;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER CELL LINE; BREAST METASTASIS; CANCER GROWTH; CARCINOGENESIS; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVITY; EPITHELIAL MESENCHYMAL TRANSITION; ESTROGEN RECEPTOR POSITIVE BREAST CANCER; FEMALE; GENE; GENE INDUCTION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IL 6GENE; IN VITRO STUDY; IN VIVO STUDY; MMP 2 GENE; MOUSE; NONHUMAN; OBESITY; PROTEIN EXPRESSION; SERPINE1 GENE; STROMA CELL; TUMOR VOLUME; ADIPOCYTE; ADIPOSE TISSUE; ANIMAL; BREAST; BREAST TUMOR; CELL MOTION; COCULTURE; GENE EXPRESSION REGULATION; GENETICS; MCF-7 CELL LINE; METABOLISM; METASTASIS; PATHOLOGY; PHYSIOLOGY; PROCEDURES; SCID MOUSE; STEM CELL; TUMOR CELL LINE;

ADIPOCYTES; ADIPOSE TISSUE; ADIPOSITY; ANIMALS; BREAST; BREAST NEOPLASMS; CARCINOGENESIS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; COCULTURE TECHNIQUES; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTERLEUKIN-6; LEPTIN; MATRIX METALLOPROTEINASE 2; MCF-7 CELLS; MICE; MICE, SCID; NEOPLASM METASTASIS; OBESITY; PLASMINOGEN ACTIVATOR INHIBITOR 1; RECEPTORS, ESTROGEN; RNA, SMALL INTERFERING; STEM CELLS; STROMAL CELLS;

EID: 84939522108     PISSN: 14655411     EISSN: 1465542X     Source Type: Journal    
DOI: 10.1186/s13058-015-0622-z     Document Type: Article

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