메뉴 건너뛰기




Volumn 32, Issue 2, 2014, Pages 539-547

Fusion of HepG2 cells with mesenchymal stem cells increases cancer-associated and malignant properties: An in vivo metastasis model

Author keywords

Aneuploidy; Fusion; In vivo models; Invasion; Metastasis; Stem cells

Indexed keywords

GELATINASE A; GELATINASE B; TRANSCRIPTION FACTOR SNAIL; TRANSCRIPTION FACTOR TWIST; UVOMORULIN; VIMENTIN;

EID: 84903190875     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2014.3264     Document Type: Article
Times cited : (43)

References (29)
  • 2
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D and Weinberg RA: Hallmarks of cancer: the next generation. Cell 144: 646-674, 2011.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 4
    • 84897990135 scopus 로고    scopus 로고
    • Tumor stroma: A complexity dictated by the hypoxic tumor microenvironment
    • Apr 22, (Epub ahead of print). doi: 10.1038/onc.2013.121
    • Casazza A, Di Conza G, Wenes M, Finisguerra V, Deschoemaeker S and Mazzone M: Tumor stroma: a complexity dictated by the hypoxic tumor microenvironment. Oncogene: Apr 22, 2013 (Epub ahead of print). doi: 10.1038/onc.2013.121.
    • (2013) Oncogene
    • Casazza, A.1    Di Conza, G.2    Wenes, M.3    Finisguerra, V.4    Deschoemaeker, S.5    Mazzone, M.6
  • 5
    • 53449094862 scopus 로고    scopus 로고
    • Stromal myofibroblasts are drivers of invasive cancer growth
    • De Wever O, Demetter P, Mareel M and Bracke M: Stromal myofibroblasts are drivers of invasive cancer growth. Int J Cancer 123: 2229-2238, 2008.
    • (2008) Int J Cancer , vol.123 , pp. 2229-2238
    • De Wever, O.1    Demetter, P.2    Mareel, M.3    Bracke, M.4
  • 7
    • 84866482255 scopus 로고    scopus 로고
    • Mesenchymal stem cells as all-round supporters in a normal and neoplastic microenvironment
    • Hass R and Otte A: Mesenchymal stem cells as all-round supporters in a normal and neoplastic microenvironment. Cell Commun Signal 10: 26, 2012.
    • (2012) Cell Commun Signal , vol.10 , pp. 26
    • Hass, R.1    Otte, A.2
  • 9
    • 84864359517 scopus 로고    scopus 로고
    • Tumor associated macrophage x cancer cell hybrids may acquire cancer stem cell properties in breast cancer
    • Ding J, Jin W, Chen C, Shao Z and Wu J: Tumor associated macrophage x cancer cell hybrids may acquire cancer stem cell properties in breast cancer. PLoS One 7: e41942, 2012.
    • (2012) PLoS One , vol.7
    • Ding, J.1    Jin, W.2    Chen, C.3    Shao, Z.4    Wu, J.5
  • 10
    • 72249120354 scopus 로고    scopus 로고
    • Cell fusion as a hidden force in tumor progression
    • Lu X and Kang Y: Cell fusion as a hidden force in tumor progression. Cancer Res 69: 8536-8539, 2009.
    • (2009) Cancer Res , vol.69 , pp. 8536-8539
    • Lu, X.1    Kang, Y.2
  • 11
    • 79960896892 scopus 로고    scopus 로고
    • Cell fusion hypothesis of the cancer stem cell
    • Lu X and Kang Y: Cell fusion hypothesis of the cancer stem cell. Adv Exp Med Biol 714: 129-140, 2011.
    • (2011) Adv Exp Med Biol , vol.714 , pp. 129-140
    • Lu, X.1    Kang, Y.2
  • 12
    • 85047690508 scopus 로고    scopus 로고
    • The origin of the cancer stem cell: Current controversies and new insights
    • DOI 101038/nrc1740
    • Bjerkvig R, Tysnes BB, Aboody KS, Najbauer J and Teris AJ: Opinion: the origin of the cancer stem cell: current controversies and new insights. Nat Rev Cancer 5: 899-904, 2005. (Pubitemid 41746034)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.11 , pp. 899-904
    • Bjerkvig, R.1    Tysnes, B.B.2    Aboody, K.S.3    Najbauer, J.4    Terzis, A.J.A.5
  • 13
    • 42549167207 scopus 로고    scopus 로고
    • Fusion of tumour cells with bone marrow-derived cells: A unifying explanation for metastasis
    • DOI 10.1038/nrc2371, PII NRC2371
    • Pawelek JM and Chakraborty AK: Fusion of tumour cells with bone marrow-derived cells: a unifying explanation for metastasis. Nat Rev Cancer 8: 377-386, 2008. (Pubitemid 351589699)
    • (2008) Nature Reviews Cancer , vol.8 , Issue.5 , pp. 377-386
    • Pawelek, J.M.1    Chakraborty, A.K.2
  • 14
    • 61449210913 scopus 로고    scopus 로고
    • A protocol for isolation and culture of mesenchymal stem cells from mouse bone marrow
    • Soleimani M and Nadri S: A protocol for isolation and culture of mesenchymal stem cells from mouse bone marrow. Nat Protoc 4: 102-106, 2009.
    • (2009) Nat Protoc , vol.4 , pp. 102-106
    • Soleimani, M.1    Nadri, S.2
  • 15
    • 0016756272 scopus 로고
    • Continuous cultures of fused cells secreting antibody of predefined specificity
    • Köhler G and Milstein C: Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 256: 495-497, 1975.
    • (1975) Nature , vol.256 , pp. 495-497
    • Köhler, G.1    Milstein, C.2
  • 16
    • 33847385008 scopus 로고    scopus 로고
    • Overexpression of NBS1 induces epithelial-mesenchymal transition and co-expression of NBS1 and Snail predicts metastasis of head and neck cancer
    • Yang MH, Chang SY, Chiou SH, Liu CJ, Chi CW, Chen PM, et al: Overexpression of NBS1 induces epithelial-mesenchymal transition and co-expression of NBS1 and Snail predicts metastasis of head and neck cancer. Oncogene 26: 1459-1467, 2007.
    • (2007) Oncogene , vol.26 , pp. 1459-1467
    • Yang, M.H.1    Chang, S.Y.2    Chiou, S.H.3    Liu, C.J.4    Chi, C.W.5    Chen, P.M.6
  • 17
    • 0842320021 scopus 로고    scopus 로고
    • Cell fusion: A hidden enemy?
    • DOI 10.1016/S1535-6108(03)00114-4, PII S1535610803001144
    • Duelli D and Lazebnik Y: Cell fusion: a hidden enemy? Cancer Cell 3: 445-448, 2003. (Pubitemid 38340291)
    • (2003) Cancer Cell , vol.3 , Issue.5 , pp. 445-448
    • Duelli, D.1    Lazebnik, Y.2
  • 18
    • 84876361173 scopus 로고    scopus 로고
    • Aneuploidy-associated gene expression signatures characterize malignant transformation in ulcerative colitis
    • Gerling M, Nousiainen K, Hautaniemi S, Krüger S, Fritzsche B, Homann N, et al: Aneuploidy-associated gene expression signatures characterize malignant transformation in ulcerative colitis. Inflamm Bowel Dis 19: 691-703, 2013.
    • (2013) Inflamm Bowel Dis , vol.19 , pp. 691-703
    • Gerling, M.1    Nousiainen, K.2    Hautaniemi, S.3    Krüger, S.4    Fritzsche, B.5    Homann, N.6
  • 19
    • 84869037071 scopus 로고    scopus 로고
    • High fat diet induced developmental defects in the mouse: Oocyte meiotic aneuploidy and fetal growth retardation/brain defects
    • Luzzo KM, Wang Q, Purcell SH, Chi M, Jimenez PT, Grindler N, et al: High fat diet induced developmental defects in the mouse: oocyte meiotic aneuploidy and fetal growth retardation/brain defects. PLoS One 7: e49217, 2012.
    • (2012) PLoS One , vol.7
    • Luzzo, K.M.1    Wang, Q.2    Purcell, S.H.3    Chi, M.4    Jimenez, P.T.5    Grindler, N.6
  • 20
    • 84872037223 scopus 로고    scopus 로고
    • Asynchronous DNA replication and aneuploidy in lymphocytes of hepatocellular carcinoma patients
    • Hanna MO, Zayed NA, Darwish H and Girgis SI: Asynchronous DNA replication and aneuploidy in lymphocytes of hepatocellular carcinoma patients. Cancer Genet 205: 636-643, 2012.
    • (2012) Cancer Genet , vol.205 , pp. 636-643
    • Hanna, M.O.1    Zayed, N.A.2    Darwish, H.3    Girgis, S.I.4
  • 21
    • 84861880210 scopus 로고    scopus 로고
    • Chromosomal instability and aneuploidy in cancer: From yeast to man
    • Pfau SJ and Amon A: Chromosomal instability and aneuploidy in cancer: from yeast to man. EMBO Rep 13: 515-527, 2012.
    • (2012) EMBO Rep , vol.13 , pp. 515-527
    • Pfau, S.J.1    Amon, A.2
  • 22
    • 85081816997 scopus 로고
    • Consideration of the possible etiology of prostatic cancer. II International Congress of Andrology, Tel Aviv, Israel
    • abs. 743
    • Stein-Werblowsky R and Ablin RJ: Consideration of the possible etiology of prostatic cancer. II International Congress of Andrology, Tel Aviv, Israel. Israel J Med Sci 17: abs. 743, 1981.
    • (1981) Israel J Med Sci , vol.17
    • Stein-Werblowsky, R.1    Ablin, R.J.2
  • 23
    • 84878583653 scopus 로고    scopus 로고
    • Overexpression of Snail induces epithelial-mesenchymal transition and a cancer stem cell-like phenotype in human colorectal cancer cells
    • Fan F, Samuel S, Evans KW, Lu J, Xia L, Zhou Y, et al: Overexpression of Snail induces epithelial-mesenchymal transition and a cancer stem cell-like phenotype in human colorectal cancer cells. Cancer Med 1: 5-16, 2012.
    • (2012) Cancer Med , vol.1 , pp. 5-16
    • Fan, F.1    Samuel, S.2    Evans, K.W.3    Lu, J.4    Xia, L.5    Zhou, Y.6
  • 24
    • 42749091317 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition and the invasive potential of tumors
    • Gavert N and Ben-Ze'ev A: Epithelial-mesenchymal transition and the invasive potential of tumors. Trends Mol Med 14: 199-209, 2008.
    • (2008) Trends Mol Med , vol.14 , pp. 199-209
    • Gavert, N.1    Ben-Ze'ev, A.2
  • 25
    • 79953166389 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein 1 induces Snail and epithelial-mesenchymal transition in metastatic nasopharyngeal carcinoma
    • Horikawa T, Yoshizaki T, Kondo S, Furukawa M, Kaizaki Y and Pagano JS: Epstein-Barr virus latent membrane protein 1 induces Snail and epithelial-mesenchymal transition in metastatic nasopharyngeal carcinoma. Br J Cancer 104: 1160-1167, 2011.
    • (2011) Br J Cancer , vol.104 , pp. 1160-1167
    • Horikawa, T.1    Yoshizaki, T.2    Kondo, S.3    Furukawa, M.4    Kaizaki, Y.5    Pagano, J.S.6
  • 26
    • 24344483881 scopus 로고    scopus 로고
    • Upregulation of MMP-9 in MDCK epithelial cell line in response to expression of the Snail transcription factor
    • DOI 10.1242/jcs.02465
    • Jordà M, Olmeda D, Vinyals A, Valero E, Cubillo E, Llorens A, et al: Upregulation of MMP-9 in MDCK epithelial cell line in response to expression of the Snail transcription factor. J Cell Sci 118: 3371-3385, 2005. (Pubitemid 41246093)
    • (2005) Journal of Cell Science , vol.118 , Issue.15 , pp. 3371-3385
    • Jorda, M.1    Olmeda, D.2    Vinyals, A.3    Valero, E.4    Cubillo, E.5    Llorens, A.6    Cano, A.7    Fabra, A.8
  • 27
    • 1842859068 scopus 로고    scopus 로고
    • Shifting paradigms in tumor metastasis: Challenges and opportunities
    • Parsons JT, Zetter B and Mohla S: Shifting paradigms in tumor metastasis: challenges and opportunities. Cancer Biol Ther 1: 582-585, 2002.
    • (2002) Cancer Biol Ther , vol.1 , pp. 582-585
    • Parsons, J.T.1    Zetter, B.2    Mohla, S.3
  • 28
    • 77953366718 scopus 로고    scopus 로고
    • Of mice and (wo)men: Mouse models of breast cancer metastasis to bone
    • Goldstein RH, Weinberg RA and Rosenblatt M: Of mice and (wo)men: mouse models of breast cancer metastasis to bone. J Bone Miner Res 25: 431-436, 2010.
    • (2010) J Bone Miner Res , vol.25 , pp. 431-436
    • Goldstein, R.H.1    Weinberg, R.A.2    Rosenblatt, M.3
  • 29
    • 79953308650 scopus 로고    scopus 로고
    • Oncogene-mediated human lung epithelial cell transformation produces adenocarcinoma phenotypes in vivo
    • Sasai K, Sukezane T, Yanagita E, Nakagawa H, Hotta A, Itoh T and Akagi T: Oncogene-mediated human lung epithelial cell transformation produces adenocarcinoma phenotypes in vivo. Cancer Res 71: 2541-2549, 2011.
    • (2011) Cancer Res , vol.71 , pp. 2541-2549
    • Sasai, K.1    Sukezane, T.2    Yanagita, E.3    Nakagawa, H.4    Hotta, A.5    Itoh, T.6    Akagi, T.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.