Tumors and inflammatory infiltrates: Friends or foes?

Clinical and Experimental Metastasis

Volumn 19, Issue 3, 2002, Pages 247-258

  Brigati, Claudio ^a   Noonan, Douglas M ^a   Albini, Adriana ^a   Benelli, Roberto ^a  

^a UNIVERSITY OF GENOA   (Italy)

Author keywords

Angiogenesis; Antibody; Chemokine; Cytokine; Inflammation; Leucocyte; Metalloproteinase; Metastasis; Tumor

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANTIBODY; ANTIINFLAMMATORY AGENT; CHEMOKINE; COPTIS RHIZOME; CYTOKINE; LEUKOTRIENE; METALLOPROTEINASE; PLANT EXTRACT; PROSTAGLANDIN; SANGUINARINE; TETRANDRINE; TUMOR ANTIGEN;

ANGIOGENESIS; ANTIINFLAMMATORY ACTIVITY; CANCER IMMUNOTHERAPY; CARCINOGENESIS; CHEMOPROPHYLAXIS; HUMAN; HUMAN CELL; INFLAMMATORY INFILTRATE; LEUKOCYTE; REVIEW; TUMOR; TUMOR GROWTH;

CHEMOKINES; CYTOKINES; HUMANS; INFLAMMATION; MODELS, BIOLOGICAL; NEOPLASMS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RECEPTORS, CYTOPLASMIC AND NUCLEAR; TRANSCRIPTION FACTORS;

EID: 0036105771     PISSN: 02620898     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1015587423262     Document Type: Review

References (123)

1. Inflammation and cancer: Back to Virkow?
2. An overview of the MAGE gene family with the identification of all human members of the family
3. Clinicopathological study on hepatocellular carcinoma with lymphocytic infiltration
4. Regression of small-cell lung carcinoma in patients with paraneoplastic neuronal antibodies
5. The biology of the 17-1A antigen (Ep-CAM)
6. Clinical trials of antibody therapy
7. A testicular antigen aberrantly expressed in human cancers detected by autologous antibody screening
8. Neutrophils as a key cellular target for angiostatin: Implications for regulation of angiogenesis and inflammation
9. Expression of adhesion molecules, platelet-activating factor, and chemokines by Kaposi's sarcoma cells
10. PAF produced by human breast cancer cells promotes migration and proliferation of tumor cells and neo-angiogenesis
11. Human neutrophils exhibit disparate chemotactic factor gene expression
12. Gene expression and production of the monokine induced by IFN-gamma (MIG), IFN-inducible T cell alpha chemoattractant (I-TAC), and IFN-gamma-inducible protein-10 (IP-10) chemokines by human neutrophils
13. Cytokine expression and release by neutrophils
14. Malignant tumor and eosinophils. Prognostic significance in gastric cancer
15. Significance of tumor associated tissue eosinophilia and other inflammatory cell infiltrate in early esophageal squamous cell carcinoma
16. Eosinophils infiltrating interleukin-5 gene-transfected tumors do not suppress tumor growth
17. Expression of adhesion molecules and chemotactic cytokines in cultured human mesothelial cells
18. Anti-tumor and immunomodulatory activity of intraperitoneal IFN-gamma in ovarian carcinoma patients with minimal residual tumor after chemotherapy
19. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor a
20. Rapid and coordinated switch in chemokine receptor expression during dendritic cell maturation
21. Distinct patterns and kinetics of chemokine production regulate dendritic cell function
22. Quantitative analysis of chemokine expression by dendritic cell subsets in vitro and in vivo
23. Human small cell lung carcinoma and carcinoid tumor regulate dendritic cell maturation and function
24. IL-4 prevents the blockade of dendritic cell differentiation induced by tumor cells
25. Activation of B lymphocytes by NK cells
26. Regulation of KIR expression in human T cells: A safety mechanism that may impair protective T-cell responses
27. Prostaglandin E2 suppressed IL-15-mediated human NK cell function through down-regulation of common gamma-chain
28. Expression and regulation of chemokine receptors in human natural killer cells
29. Alterations in signal transduction molecules in T lymphocytes from tumor-bearing mice
30. Peripheral burst of tumor-specific cytotoxic T lymphocytes and infiltration of metastatic lesions by memory CD8+ T cells in melanoma patients receiving interleukin 12
31. Antitumor effects of the combination therapy with TNF-alpha gene-modified tumor cells and interleukin 12 in a melanoma model in mice
32. Cytokines, tumour-cell death and immunogenicity: A question of choice
33. The origin and function of tumor-associated macrophages
34. Mice deficient in tumor necrosis factor-alpha are resistant to skin carcinogenesis
35. TNF-alpha and IL-1beta selectively induce expression of 92-kDa gelatinase by human macrophages
36. Serum-soluble IL-2 receptor and IL-6 levels in patients with melanoma
37. The localization of thrombospondin-1 (TSP-1), cysteine-serine-valine-threonine-cysteine-glycine (CSVTCG) TSP receptor, and matrix metalloproteinase-9 (MMP-9) in colorectal cancer
38. Transforming growth factor-beta: Recent progress and new challenges
39. Delayed wound healing in immunodeficient TGF-beta 1 knockout mice
40. Invasion and metastasis of a mammary tumor involves TGF-beta signaling
41. TGF-beta-based immunotherapy for cancer: Breaching the tumor firewall
42. Antitumor and antimetastatic effects of interleukin 12
43. Evidence for IL-12-activated Ca2+ and tyrosine signaling pathways in human neutrophils
44. Platelet-activating factor synthesized by IL-12-stimulated polymorphonuclear neutrophils and NK cells mediates chemotaxis
45. Interleukin 1 alpha acts as an autocrine growth stimulator for human gastric carcinoma cells
46. Role of interleukin-8 in tumor growth and metastasis of human melanoma
47. Inflammation is responsible for the development of wound-induced tumors in chickens infected with Rous sarcoma virus
48. Tumor-associated macrophages in neoplastic progression: A paradigm for the in vivo function of chemokines
49. Chemokines
50. Induction of functional IL-8 receptors by IL-4 and IL-13 in human monocytes
51. Interleukin-12 and interleukin-18 synergistically induce murine tumor regression which involves inhibition of angiogenesis
52. IL-2 up-regulates but IFN-gamma suppresses IL-8 expression in human monocytes
53. The CXC chemokine receptor 2, CXCR2, is the putative receptor for ELR+ CXC chemokine-induced angiogenic activity
54. Cell cycle-dependent expression of CXC chemokine receptor 3 by endothelial cells mediates angiostatic activity
55. Endothelial cells differentially express functional CXC-chemokine receptor-4 (CXCR-4/fusin) under the control of autocrine activity and exogenous cytokines
56. The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract
57. Human endothelial cells express CCR2 and respond to MCP-1: Direct role of MCP-1 in angiogenesis and tumor progression
58. Human immunodeficiency virus transactivator protein (Tat) stimulates chemotaxis, calcium mobilization, and activation of human polymorphonuclear leukocytes: Implications for Tat-mediated pathogenesis
59. Chemokines induce migrational responses in human breast carcinoma cell lines
60. Involvement of chemokine receptors in breast cancer metastasis
61. Mechanism and biological significance of constitutive expression of MgSA/GRO chemokines in malignant melanoma tumor progression
62. Identification of a novel granulocyte chemotactic protein (GCP-2) from human tumor cells. In vitro and in vivo comparison with natural forms of GRO, IP-10, and IL-8
63. Inhibition of interleukin 8 attenuates angiogenesis in bronchogenic carcinoma
64. Interleukin-8 and related chemotactic cytokines-CXC and CC chemokines
65. Regulation of the macrophage content of neoplasms by chemoattractants
66. MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis
67. Piceatannol, a stilbene phytochemical, inhibits mitochondrial F0F1-ATPase activity by targeting the F1 complex
68. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes
69. Extracellular ATP and TNF-alpha synergize in the activation and maturation of human dendritic cells
70. Integrin-dependent homotypic adhesion of neutrophils. Arachidonic acid activates Raf-1/Mek/Erk via a 5-lipoxygenase- dependent pathway
71. Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1alpha in vascular smooth muscle cells
72. Ulcerative colitis and colorectal cancer
73. Arsenic trioxide induces doseand time-dependent apoptosis of endothelium and may exert an antileukemic effect via inhibition of angiogenesis
74. Limited proteolysis of angiogenin by elastase is regulated by plasminogen
75. The combined action of IL-15 and IL-12 gene transfer can induce tumor cell rejection without T and NK cell involvement
76. The intriguing role of polymorphonuclear neutrophils in antitumor reactions
77. Low-level monocyte chemoattractant protein-1 stimulation of monocytes leads to tumor formation in nontumorigenic melanoma cells
78. Threshold levels of gene expression of the melanoma antigen gp 100 correlate with tumor cell recognition by cytotoxic T lymphocytes
79. The immunology and immunotherapy of breast cancer: An update
80. Anti-T antibodies and peanut-agglutinin-binding glycoproteins in sera of patients with gastric cancer
81. Tumor-specific cytokine release by donor T cells induces an effective host anti-tumor response through recruitment of host naive antigen presenting cells
82. Fas/Fas ligand interaction in human colorectal hepatic metastases: A mechanism of hepatocyte destruction to facilitate local tumor invasion
83. Tumor cells cotransduced with B7.1 and gamma-IFN induce effective rejection of established parental tumor
84. Bone marrow-generated dendritic cells pulsed with a class I-restricted peptide are potent inducers of cytotoxic T lymphocytes
85. Herceptin((R)) Alone or in combination with chemotherapy in the treatment of HER2-positive metastatic breast cancer: Pivotal trials
86. A phase II study of the bispecific antibody MDX-H210 (anti-HER2 x CD64) with GM-CSF in HER2+ advanced prostate cancer
87. A candidate for cancer gene therapy: MIP-1 alpha gene transfer to an adenocarcinoma cell line reduced tumorigenicity and induced protective immunity in immunocompetent mice
88. The CXC chemokines IP-10 and Mig are necessary for IL-12-mediated regression of the mouse RENCA tumor
89. Combined chemokine and cytokine gene transfer enhances antitumor immunity
90. A synthetic peptide inhibitor for alpha-chemokines inhibits the tumour growth and pulmonary metastasis of human melanoma cells in nude mice
91. Suppression of intestinal polyposis by inhibition of COX-2 in Apc knockout mice
92. Elevated cyclooxygenase-2 levels in Min mouse adenomas
93. Association of aspirin and other NSAID use with incidence of postmenopausal breast cancer
94. Antimetastatic effect of flurbiprofen and other platelet aggregation inhibitors
95. Induction of apoptotic cell death in human colorectal carcinoma cell lines by a cyclooxygenase-2 (COX-2)-selective nonsteroidal anti-inflammatory drug: Independence from COX-2 protein expression
96. Induction of apoptosis in colon cancer cells by cyclooxygenase-2 inhibitor NS398 through a cytochrome c-dependent pathway
97. Fatty acid CoA-ligase 4 and cyclooxygenase 2 promote carcinogenesis by lowering the intracellular level of free arachidonic acid
98. Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential
99. PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines
100. Activation of the peroxisome proliferator-activated receptor gamma promotes the development of colon tumors in C57BL/6J-APCMin/+ mice
101. PPAR delta is an APC-regulated target of nonsteroidal anti-indlammatory drugs
102. Expression of cyclooxygenase-2 in prostate carcinoma
103. Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: Insight into mechanisms and implications for cancer growth and ulcer healing
104. PML nuclear bodies are general targets for inflammation and cell proliferation
105. A new method of antitumor therapy with a high dose of TNF perfusion for unresectable liver tumors
106. Linomide inhibits angiogenesis, growth, metastasis, and macrophage infiltration within rat prostatic cancers
107. The antiangiogenic agent tinomide inhibits tumor necrosis factor-alpha secretion via inhibition of its synthesis
108. Effects of thalidomide and related metabolites in a mouse corneal model of neovascularization
109. Continuous low dose Thalidomide: A phase II study in advanced melanoma, renal cell, ovarian and breast cancer
110. Role of tumor necrosis factor-alpha inhibition with inflixiMAB in cancer therapy and hematopoietic stem cell transplantation
111. Biological implications of growth factors on the mechanism of invasion in gynecological tumor cells
112. On the role of hydroxyl radical and the effect of tetrandrine on nuclear factor-kappaB activation by phorbol 12-myristate 13-acetate
113. Differential antiproliferative and apoptotic response of sanguinarine for cancer cells versus normal cells
114. Induction of apoptosis by hydrolyzable tannins from Eugenia jambos L. on human leukemia cells
115. Ajoene, a natural product with non-steroidal anti-inflammatory drug (NSAID)-like properties?
116. Anticachectic effects of Coptidis rhizoma, an anti-inflammatory herb, on esophageal cancer cells that produce interleukin 6
117. Esculentoside A inhibits tumor necrosis factor, interleukin-1, and interleukin-6 production induced by lipopolysaccharide in mice
118. Two stages of cancer prevention with green tea
119. Tumor invasion: Molecular shears blunted by green tea
120. Synergy between ethanol and grape polyphenols, quercetin, and resveratrol, in the inhibition of the inducible nitric oxide synthase pathway
121. Reduction of oxidative stress and cytokine-induced neutrophil chemoattractant (CINC) expression by red wine polyphenols in zinc deficiency induced intestinal damage of rat
122. Potent inhibitory action of red wine polyphenols on human breast cancer cells
123. Angioprevention: Angiogenesis is a common and key target for cancer chemopreventive agents