The direct actions of GABA, 2'-methoxy-6-methylflavone and general anaesthetics at β3γ2L GABAA receptors: Evidence for receptors with different subunit stoichiometries

PLoS ONE

Volumn 10, Issue 10, 2015, Pages

  Chua, Han Chow ^a   Absalom, Nathan L ^a   Hanrahan, Jane R ^a   Viswas, Raja ^a   Chebib, Mary ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

2' METHOXY 6 METHYLFLAVONE; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA2; 4 AMINOBUTYRIC ACID A RECEPTOR BETA3; 4 AMINOBUTYRIC ACID A RECEPTOR GAMMA2; ANESTHETIC AGENT; ETOMIDATE; FLAVONOID; MESSENGER RNA; PROPOFOL; UNCLASSIFIED DRUG; 2'-METHOXY-6-METHYLFLAVONE; 4 AMINOBUTYRIC ACID A RECEPTOR STIMULATING AGENT; BENZODIAZEPINE RECEPTOR AFFECTING AGENT; CHLORIDE; FLAVONE DERIVATIVE; FLUMAZENIL; INTRAVENOUS ANESTHETIC AGENT; PROTEIN SUBUNIT; ZINC CHLORIDE; ZINC DERIVATIVE;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG BINDING SITE; FEMALE; NONHUMAN; OOCYTE; STOICHIOMETRY; VOLTAGE CLAMP TECHNIQUE; XENOPUS; ANIMAL; CELL CULTURE; DOSE RESPONSE; HUMAN; METABOLISM; PRECLINICAL STUDY; PROTEIN SUBUNIT; XENOPUS LAEVIS;

ANESTHETICS, INTRAVENOUS; ANIMALS; CELLS, CULTURED; CHLORIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; ETOMIDATE; FEMALE; FLAVONES; FLUMAZENIL; GABA MODULATORS; GABA-A RECEPTOR AGONISTS; HUMANS; PROPOFOL; PROTEIN SUBUNITS; RECEPTORS, GABA-A; XENOPUS LAEVIS; ZINC COMPOUNDS;

EID: 84949938484     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0141359     Document Type: Article

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