메뉴 건너뛰기




Volumn 19, Issue 8, 1999, Pages 2960-2973

Single-channel properties of synaptic and extrasynaptic GABA(A) receptors suggest differential targeting of receptor subtypes

Author keywords

Cerebellar granule cell; Differential targeting; GABA(A) receptor; Single channel; Subunit heterogeneity; Synaptic

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; RECEPTOR SUBTYPE;

EID: 0033561229     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.19-08-02960.1999     Document Type: Article
Times cited : (210)

References (67)
  • 2
    • 0027340033 scopus 로고
    • 2s subunits produce unique ion channels with dissimilar single-channel properties
    • 2s subunits produce unique ion channels with dissimilar single-channel properties. J Neurosci 13:1429-1440.
    • (1993) J Neurosci , vol.13 , pp. 1429-1440
    • Angelotti, T.P.1    Macdonald, R.L.2
  • 4
    • 0015169402 scopus 로고
    • Pharmacological properties of inhibitions in the cerebellar cortex
    • Bisti S, Iosif G, Marchesi GF, Strata P (1971) Pharmacological properties of inhibitions in the cerebellar cortex. Exp Brain Res 14:24-37.
    • (1971) Exp Brain Res , vol.14 , pp. 24-37
    • Bisti, S.1    Iosif, G.2    Marchesi, G.F.3    Strata, P.4
  • 5
    • 0028036284 scopus 로고
    • Large amplitude variability of GABAergic IPSCs in melanotropes from Xenopus laevis: Evidence that quantal size differs between synapses
    • Borst JG, Lodder JC, Kits KS (1994) Large amplitude variability of GABAergic IPSCs in melanotropes from Xenopus laevis: evidence that quantal size differs between synapses. J Neurophysiol 71:639-655.
    • (1994) J Neurophysiol , vol.71 , pp. 639-655
    • Borst, J.G.1    Lodder, J.C.2    Kits, K.S.3
  • 8
    • 0031023896 scopus 로고    scopus 로고
    • A direct comparison of the single-channel properties of synaptic and extrasynaptic NMDA receptors
    • Clark BA, Farrant M, Cull-Candy SG (1997) A direct comparison of the single-channel properties of synaptic and extrasynaptic NMDA receptors. J Neurosci 17:107-116.
    • (1997) J Neurosci , vol.17 , pp. 107-116
    • Clark, B.A.1    Farrant, M.2    Cull-Candy, S.G.3
  • 9
    • 0023856335 scopus 로고
    • Activation of ion channels in the frog end-plate by high concentrations of acetylcholine
    • Colquhoun D, Ogden D (1988) Activation of ion channels in the frog end-plate by high concentrations of acetylcholine. J Physiol (Lond) 395:131-159.
    • (1988) J Physiol (Lond) , vol.395 , pp. 131-159
    • Colquhoun, D.1    Ogden, D.2
  • 10
    • 0001774017 scopus 로고
    • Fitting and statistical analysis of singlechannel records
    • Sakmann B, Neher E, eds, New York: Plenum
    • Colquhoun D, Sigworth F (1995) Fitting and statistical analysis of singlechannel records. In: Single-channel recording (Sakmann B, Neher E, eds), pp 483-587. New York: Plenum.
    • (1995) Single-channel Recording , pp. 483-587
    • Colquhoun, D.1    Sigworth, F.2
  • 11
    • 0030043594 scopus 로고    scopus 로고
    • Assembly and cell surface expression of heteromeric and homomeric γ-aminobutyric acid type A receptors
    • Connolly CN, Krishek BJ, McDonald BJ, Smart TO, Moss SJ (1996a) Assembly and cell surface expression of heteromeric and homomeric γ-aminobutyric acid type A receptors. J Biol Chem 271:89-96.
    • (1996) J Biol Chem , vol.271 , pp. 89-96
    • Connolly, C.N.1    Krishek, B.J.2    McDonald, B.J.3    Smart, T.O.4    Moss, S.J.5
  • 12
    • 0029796551 scopus 로고    scopus 로고
    • Subcellular localization of γ-aminobutyric acid type A receptors is determined by receptor β subunits
    • Connolly CN, Wooltorton JR. Smart TG, Moss SJ (1996b) Subcellular localization of γ-aminobutyric acid type A receptors is determined by receptor β subunits. Proc Natl Acad Sci USA 93:9899-9904.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 9899-9904
    • Connolly, C.N.1    Wooltorton, J.R.2    Smart, T.G.3    Moss, S.J.4
  • 13
    • 0029968898 scopus 로고    scopus 로고
    • Clustering of gephyrin at GABAergic but not glutamatergic synapses in cultured rat hippocampal neurons
    • Craig AM, Banker G, Chang W, McGrath ME, Serpinskaya AS (1996) Clustering of gephyrin at GABAergic but not glutamatergic synapses in cultured rat hippocampal neurons. J Neurosci 16:3166-3177.
    • (1996) J Neurosci , vol.16 , pp. 3166-3177
    • Craig, A.M.1    Banker, G.2    Chang, W.3    McGrath, M.E.4    Serpinskaya, A.S.5
  • 18
    • 0025860063 scopus 로고
    • Excitatory amino acid receptorchannels in Purkinje cells in thin cerebellar slices
    • Farrant M, Cull-Candy SG (1991) Excitatory amino acid receptorchannels in Purkinje cells in thin cerebellar slices. Proc R Soc Lond B Biol SCi 244:179-184.
    • (1991) Proc R Soc Lond B Biol SCi , vol.244 , pp. 179-184
    • Farrant, M.1    Cull-Candy, S.G.2
  • 19
    • 0028295715 scopus 로고
    • NMDA-receptor channel diversity in the developing cerebellum
    • Farrant M, Feldmeyer D, Takahashi T, Cull-Candy SG (1994) NMDA-receptor channel diversity in the developing cerebellum. Nature 368:335-339.
    • (1994) Nature , vol.368 , pp. 335-339
    • Farrant, M.1    Feldmeyer, D.2    Takahashi, T.3    Cull-Candy, S.G.4
  • 20
    • 0002526783 scopus 로고
    • Benzodiazepine modulation of GABA-activated currents in granule cells of the rat cerebellum
    • Farrant M, Kaneda M, Cull-Candy SG (1995) Benzodiazepine modulation of GABA-activated currents in granule cells of the rat cerebellum. J Physiol (Lond)498P:17.
    • (1995) J Physiol (Lond) , vol.498 P , pp. 17
    • Farrant, M.1    Kaneda, M.2    Cull-Candy, S.G.3
  • 22
    • 11944265824 scopus 로고
    • Five subtypes of type A γ-aminobutyric acid receptors identified in neurons by double and triple immunofluorescence staining with subunit-specific antibodies
    • Fritschy JM, Benke D, Mertens S, Oertel WH. Bachi T, Mohler H (1992) Five subtypes of type A γ-aminobutyric acid receptors identified in neurons by double and triple immunofluorescence staining with subunit-specific antibodies. Proc Nat Acad SCi USA 89:6726-6730.
    • (1992) Proc Nat Acad SCi USA , vol.89 , pp. 6726-6730
    • Fritschy, J.M.1    Benke, D.2    Mertens, S.3    Oertel, W.H.4    Bachi, T.5    Mohler, H.6
  • 24
    • 0032103933 scopus 로고    scopus 로고
    • Localization of the clustering protein gephyrin at GABAergic synapses in the main olfactory bulb of the rat
    • Giustetto M, Kirsch J, Fritschy JM, Cantino D, Sassoè-Pognetto M (1998) Localization of the clustering protein gephyrin at GABAergic synapses in the main olfactory bulb of the rat. J Comp Neurol 395:231-244.
    • (1998) J Comp Neurol , vol.395 , pp. 231-244
    • Giustetto, M.1    Kirsch, J.2    Fritschy, J.M.3    Cantino, D.4    Sassoè-Pognetto, M.5
  • 26
    • 0020518747 scopus 로고
    • Activation of multipleconductance state chloride channels in spinal neurones by glycine and GABA
    • Hamill OP, Bormann J, Sakmann B (1983) Activation of multipleconductance state chloride channels in spinal neurones by glycine and GABA. Nature 305:805-808.
    • (1983) Nature , vol.305 , pp. 805-808
    • Hamill, O.P.1    Bormann, J.2    Sakmann, B.3
  • 27
    • 0024533126 scopus 로고
    • Two types of GABA-containing axon terminals in cerebellar glomeruli of cat: An immunogold-EM study
    • Hámori J, Takács J (1989) Two types of GABA-containing axon terminals in cerebellar glomeruli of cat: an immunogold-EM study. Exp Brain Res 74:471-479.
    • (1989) Exp Brain Res , vol.74 , pp. 471-479
    • Hámori, J.1    Takács, J.2
  • 29
    • 0029112106 scopus 로고
    • A channel responses to brief agonist pulses
    • A channel responses to brief agonist pulses. Neuron 15:181-191.
    • (1995) Neuron , vol.15 , pp. 181-191
    • Jones, M.V.1    Westbrook, G.L.2
  • 30
    • 0030867840 scopus 로고    scopus 로고
    • Shaping of IPSCs by endogenous calcineurin activity
    • Jones MV, Westbrook GL (1997) Shaping of IPSCs by endogenous calcineurin activity. J Neurosci 17:7626-7633.
    • (1997) J Neurosci , vol.17 , pp. 7626-7633
    • Jones, M.V.1    Westbrook, G.L.2
  • 31
    • 0029028314 scopus 로고
    • Whole-cell and singlechannel currents activated by GABA and glycine in granule cells of the rat cerebellum
    • Kaneda M, Farrant M, Cull-Candy SG (1995) Whole-cell and singlechannel currents activated by GABA and glycine in granule cells of the rat cerebellum. J Physiol (Lond) 485:419-435.
    • (1995) J Physiol (Lond) , vol.485 , pp. 419-435
    • Kaneda, M.1    Farrant, M.2    Cull-Candy, S.G.3
  • 34
    • 0026612362 scopus 로고
    • A receptor subunit mRNAs in the rat brain. II. Olfactory bulb and cerebellum
    • A receptor subunit mRNAs in the rat brain. II. Olfactory bulb and cerebellum. J Neurosci 12:1063-1076.
    • (1992) J Neurosci , vol.12 , pp. 1063-1076
    • Laurie, D.J.1    Seeburg, P.H.2    Wisden, W.3
  • 40
    • 0025363017 scopus 로고
    • A receptor complex in an inhibitory synaptic circuit in the rat cerebellum
    • A receptor complex in an inhibitory synaptic circuit in the rat cerebellum. Dev Brain Res 55:73-86.
    • (1990) Dev Brain Res , vol.55 , pp. 73-86
    • Meinecke, D.L.1    Rakic, P.2
  • 41
    • 0030828318 scopus 로고    scopus 로고
    • A receptors in cultured murine cerebellar granule cells
    • A receptors in cultured murine cerebellar granule cells. J Physiol (Lond) 503:353-369.
    • (1997) J Physiol (Lond) , vol.503 , pp. 353-369
    • Mellor, J.R.1    Randall, A.D.2
  • 42
    • 0025961741 scopus 로고
    • Single channels activated by high concentrations of GABA in superior cervical ganglion neurones of the rat
    • Newland CF, Colquhoun D, Cull-Candy SG (1991) Single channels activated by high concentrations of GABA in superior cervical ganglion neurones of the rat. J Physiol (Lond) 432:203-233.
    • (1991) J Physiol (Lond) , vol.432 , pp. 203-233
    • Newland, C.F.1    Colquhoun, D.2    Cull-Candy, S.G.3
  • 44
    • 0029909204 scopus 로고    scopus 로고
    • Differential synaptic localization of two major γ-aminobutyric acid type A receptor alpha subunits on hippocampal pyramidal cells
    • Nusser Z, Sieghart W, Benke D, Fritschy JM, Somogyi P (1996) Differential synaptic localization of two major γ-aminobutyric acid type A receptor alpha subunits on hippocampal pyramidal cells. Proc Natl Acad Sci USA 93:11939-11944.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 11939-11944
    • Nusser, Z.1    Sieghart, W.2    Benke, D.3    Fritschy, J.M.4    Somogyi, P.5
  • 45
    • 0030922803 scopus 로고    scopus 로고
    • A receptor number underlie variation in GABA mini amplitude
    • A receptor number underlie variation in GABA mini amplitude. Neuron 19:697-709.
    • (1997) Neuron , vol.19 , pp. 697-709
    • Nusser, Z.1    Cull-Candy, S.2    Farrant, M.3
  • 46
    • 0032008543 scopus 로고    scopus 로고
    • A receptors to synaptic and extrasynaptic membranes of cercbellar granule cells
    • A receptors to synaptic and extrasynaptic membranes of cercbellar granule cells. J Neurosci 18:1693-1703.
    • (1998) J Neurosci , vol.18 , pp. 1693-1703
    • Nusser, Z.1    Sieghart, W.2    Somogyi, P.3
  • 47
    • 0023691977 scopus 로고
    • Sodium-channel subconductance levels measured with a new variance-mean analysis
    • Patlak JB (1988) Sodium-channel subconductance levels measured with a new variance-mean analysis. J Gen Physiol 92:413-430.
    • (1988) J Gen Physiol , vol.92 , pp. 413-430
    • Patlak, J.B.1
  • 48
    • 0030611972 scopus 로고    scopus 로고
    • A synapses during flurazepam withdrawal are region-specific in the hippocampal formation
    • A synapses during flurazepam withdrawal are region-specific in the hippocampal formation. J Neurosci 17:3467-3475.
    • (1997) J Neurosci , vol.17 , pp. 3467-3475
    • Poisbeau, P.1    Williams, S.R.2    Mody, I.3
  • 50
    • 0032486422 scopus 로고    scopus 로고
    • The tetrameric structure of a glutamate receptor channel
    • Rosenmund C, Stern-Bach Y, Stevens CF (1998) The tetrameric structure of a glutamate receptor channel. Science 280:1596-1599.
    • (1998) Science , vol.280 , pp. 1596-1599
    • Rosenmund, C.1    Stern-Bach, Y.2    Stevens, C.F.3
  • 51
    • 0032055975 scopus 로고    scopus 로고
    • A receptors and glomerular geometry
    • A receptors and glomerular geometry. Neuron 20:783-795.
    • (1998) Neuron , vol.20 , pp. 783-795
    • Rossi, D.J.1    Hamann, M.2
  • 52
    • 0019215162 scopus 로고
    • Single acetylcholine-activated channels show burst-kinetics in presence of desensitizing concentrations of agonist
    • Sakmann B, Patlak J, Neher E (1980) Single acetylcholine-activated channels show burst-kinetics in presence of desensitizing concentrations of agonist. Nature 286:71-73.
    • (1980) Nature , vol.286 , pp. 71-73
    • Sakmann, B.1    Patlak, J.2    Neher, E.3
  • 53
    • 0026514176 scopus 로고
    • Rapid-time-course miniature and evoked excitatory currents at cerebellar synapses in situ
    • Silver RA, Traynelis SF, Cull-Candy SG (1992) Rapid-time-course miniature and evoked excitatory currents at cerebellar synapses in situ. Nature 355:163-166.
    • (1992) Nature , vol.355 , pp. 163-166
    • Silver, R.A.1    Traynelis, S.F.2    Cull-Candy, S.G.3
  • 54
    • 0029947040 scopus 로고    scopus 로고
    • Non-NMDA glutamate receptor occupancy and open probability at a rat cerebellar synapse with single and multiple release sites
    • Silver RA, Cull-Candy SG, Takahashi T (1996) Non-NMDA glutamate receptor occupancy and open probability at a rat cerebellar synapse with single and multiple release sites. J Physiol (Lond) 494:231-250.
    • (1996) J Physiol (Lond) , vol.494 , pp. 231-250
    • Silver, R.A.1    Cull-Candy, S.G.2    Takahashi, T.3
  • 56
    • 18144445554 scopus 로고    scopus 로고
    • A receptor is concentrated in synaptic junctions containing the α1 and β2/3 subunits in hippocampus, cerebellum and globus pallidus
    • A receptor is concentrated in synaptic junctions containing the α1 and β2/3 subunits in hippocampus, cerebellum and globus pallidus. Neuropharmacology 35:1425-1444.
    • (1996) Neuropharmacology , vol.35 , pp. 1425-1444
    • Somogyi, P.1    Fritschy, J.M.2    Benke, D.3    Roberts, J.D.4    Sieghart, W.5
  • 58
    • 0032055604 scopus 로고    scopus 로고
    • Getting the most out of noise in the central nervous system
    • Traynelis SF, Jaramillo F (1998) Getting the most out of noise in the central nervous system. Trends Neurosci 21:137-145.
    • (1998) Trends Neurosci , vol.21 , pp. 137-145
    • Traynelis, S.F.1    Jaramillo, F.2
  • 59
    • 0027282156 scopus 로고
    • Estimated conductance of glutamate receptor channels activated during EPSCs at the cerebellar mossy fiber-granule cell synapse
    • Traynelis SF, Silver RA, Cull-Candy SG (1993) Estimated conductance of glutamate receptor channels activated during EPSCs at the cerebellar mossy fiber-granule cell synapse. Neuron 11:279-289.
    • (1993) Neuron , vol.11 , pp. 279-289
    • Traynelis, S.F.1    Silver, R.A.2    Cull-Candy, S.G.3
  • 62
    • 0030989766 scopus 로고    scopus 로고
    • A receptor-mediated currents in granule cells of postnatal rat cerebellum
    • A receptor-mediated currents in granule cells of postnatal rat cerebellum. Eur J Neurosci 9:533-548.
    • (1997) Eur J Neurosci , vol.9 , pp. 533-548
    • Wall, M.J.1    Usowicz, M.M.2
  • 64
    • 0026612363 scopus 로고
    • A receptor subunit mRNAs in the rat brain. I. Telencephalon, diencephalon, mesencephalon
    • A receptor subunit mRNAs in the rat brain. I. Telencephalon, diencephalon, mesencephalon. J Neurosci 12:1040-1062.
    • (1992) J Neurosci , vol.12 , pp. 1040-1062
    • Wisden, W.1    Laurie, D.J.2    Monyer, H.3    Seeburg, P.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.