The neoflavonoid latifolin isolated from meoh extract of Dalbergia odorifera attenuates inflammatory responses by inhibiting NF-κB activation via Nrf2-mediated heme oxygenase-1 expression

Phytotherapy Research

Volumn 28, Issue 8, 2014, Pages 1216-1223

  Lee, Dong Sung ^a   Kim, Kyoung Su ^a   Ko, Wonmin ^a   Li, Bin ^a   Keo, Samell ^a   Jeong, Gil Saeng ^b   Oh, Hyuncheol ^a   Kim, Youn Chul ^a  

^a Wonkwang University   (South Korea)

^b Keimyung University   (South Korea)

Author keywords

Dalbergia odorifera; heme oxygenase 1; inflammation; latifolin; macrophages; nuclear factor B

Indexed keywords

CYCLOOXYGENASE 2; DALBERGIA ODORIFERA EXTRACT; FLAVONOID; HEME OXYGENASE 1; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; LATIFOLIN; LIPOPOLYSACCHARIDE; MESSENGER RNA; NITRIC OXIDE; PLANT EXTRACT; PROSTAGLANDIN E2; PROTOPORPHYRIN TIN; THIOGLYCOLIC ACID; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL VIABILITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DALBERGIA; DALBERGIA ODORIFERA; DRUG ISOLATION; DRUG POTENCY; DRUG STRUCTURE; ENZYME INDUCTION; NONHUMAN; PERITONEUM MACROPHAGE; PROTEIN DNA BINDING; PROTEIN EXPRESSION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; TRANSCRIPTION TERMINATION;

DALBERGIA ODORIFERA; MURINAE;

DALBERGIA ODORIFERA; HEME OXYGENASE-1; INFLAMMATION; LATIFOLIN; MACROPHAGES; NUCLEAR FACTOR-ΚB;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELLS, CULTURED; CYCLOOXYGENASE 2; DALBERGIA; DINOPROSTONE; HEME OXYGENASE-1; I-KAPPA B PROTEINS; INFLAMMATION; INTERLEUKIN-1BETA; MACROPHAGES, PERITONEAL; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; NF-E2-RELATED FACTOR 2; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; PHENOLS; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84905657813     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.5119     Document Type: Article

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