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Volumn 14, Issue 12, 2015, Pages 1173-1185

Virulence-associated enzymes of Cryptococcus neoformans

Author keywords

[No Author keywords available]

Indexed keywords

MELANIN; POLYSACCHARIDE;

EID: 84949033948     PISSN: 15359778     EISSN: None     Source Type: Journal    
DOI: 10.1128/EC.00103-15     Document Type: Review
Times cited : (92)

References (202)
  • 1
    • 62349130224 scopus 로고    scopus 로고
    • Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS
    • Park BJ, Wannemuehler KA, Marston BJ, Govender N, Pappas PG, Chiller TA. 2009. Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS. AIDS 23:525-530. http://dx.doi.org/10.1097/QAD.0b013e328322ffac.
    • (2009) AIDS , vol.23 , pp. 525-530
    • Park, B.J.1    Wannemuehler, K.A.2    Marston, B.J.3    Govender, N.4    Pappas, P.G.5    Chiller, T.A.6
  • 3
    • 34250847645 scopus 로고    scopus 로고
    • Cryptococcus neoformans mates on pigeon guano: Implications for the realized ecological niche and globalization
    • Nielsen K, De Obaldia AL, Heitman J. 2007. Cryptococcus neoformans mates on pigeon guano: implications for the realized ecological niche and globalization. Eukaryot Cell 6:949-959. http://dx.doi.org/10.1128/EC.00097-07.
    • (2007) Eukaryot Cell , vol.6 , pp. 949-959
    • Nielsen, K.1    De Obaldia, A.L.2    Heitman, J.3
  • 4
    • 0028786641 scopus 로고
    • Cryptococcosis in the era of AIDS—100 years after the discovery of Cryptococcus neoformans
    • Mitchell TG, Perfect JR. 1995. Cryptococcosis in the era of AIDS—100 years after the discovery of Cryptococcus neoformans. Clin Microbiol Rev 8:515-548.
    • (1995) Clin Microbiol Rev , vol.8 , pp. 515-548
    • Mitchell, T.G.1    Perfect, J.R.2
  • 5
    • 0002223485 scopus 로고    scopus 로고
    • Laccase and melanin in the pathogenesis of Cryptococcus neoformans
    • Williamson PR. 1997. Laccase and melanin in the pathogenesis of Cryptococcus neoformans. Front Biosci 2:e99-e107.
    • (1997) Front Biosci , vol.2
    • Williamson, P.R.1
  • 6
    • 0033900087 scopus 로고    scopus 로고
    • Melanin and virulence in Cryptococcus neoformans
    • Casadevall A, Rosas AL, Nosanchuk JD. 2000. Melanin and virulence in Cryptococcus neoformans. Curr Opin Microbiol 3:354-358. http://dx.doi.org/10.1016/S1369-5274(00)00103-X.
    • (2000) Curr Opin Microbiol , vol.3 , pp. 354-358
    • Casadevall, A.1    Rosas, A.L.2    Nosanchuk, J.D.3
  • 9
    • 0000793172 scopus 로고
    • A galactoxylomannan antigen of Cryptococcus neoformans serotype A
    • Cherniak R, Reiss E, Turner SH. 1982. A galactoxylomannan antigen of Cryptococcus neoformans serotype A. Carbohydr Res 103:239-250. http://dx.doi.org/10.1016/S0008-6215(00)80686-2.
    • (1982) Carbohydr Res , vol.103 , pp. 239-250
    • Cherniak, R.1    Reiss, E.2    Turner, S.H.3
  • 10
    • 0028216864 scopus 로고
    • Polysaccharide antigens of the capsule of Cryptococcus neoformans
    • Cherniak R, Sundstrom JB. 1994. Polysaccharide antigens of the capsule of Cryptococcus neoformans. Infect Immun 62:1507-1512.
    • (1994) Infect Immun , vol.62 , pp. 1507-1512
    • Cherniak, R.1    Sundstrom, J.B.2
  • 11
    • 0043234292 scopus 로고    scopus 로고
    • A yeast under cover: The capsule of Cryptococcus neoformans
    • Bose I, Reese AJ, Ory JJ, Janbon G, Doering TL. 2003. A yeast under cover: the capsule of Cryptococcus neoformans. Eukaryot Cell 2:655-663. http://dx.doi.org/10.1128/EC.2.4.655-663.2003.
    • (2003) Eukaryot Cell , vol.2 , pp. 655-663
    • Bose, I.1    Reese, A.J.2    Ory, J.J.3    Janbon, G.4    Doering, T.L.5
  • 12
    • 0242668758 scopus 로고    scopus 로고
    • Antigenic and biological characteristics of mutant strains of Cryptococcus neoformans lacking capsularOacetylation or xylosyl side chains
    • Kozel TR, Levitz SM, Dromer F, Gates MA, Thorkildson P, Janbon G. 2003. Antigenic and biological characteristics of mutant strains of Cryptococcus neoformans lacking capsularOacetylation or xylosyl side chains. Infect Immun 71:2868-2875. http://dx.doi.org/10.1128/IAI.71.5.2868-2875.2003.
    • (2003) Infect Immun , vol.71 , pp. 2868-2875
    • Kozel, T.R.1    Levitz, S.M.2    Dromer, F.3    Gates, M.A.4    Thorkildson, P.5    Janbon, G.6
  • 13
    • 64949138345 scopus 로고    scopus 로고
    • The structure of Cryptococcus neoformans galactoxylomannan contains beta-Dglucuronic acid
    • Heiss C, Klutts JS, Wang Z, Doering TL, Azadi P. 2009. The structure of Cryptococcus neoformans galactoxylomannan contains beta-Dglucuronic acid. Carbohydr Res 344:915-920. http://dx.doi.org/10.1016/j.carres.2009.03.003.
    • (2009) Carbohydr Res , vol.344 , pp. 915-920
    • Heiss, C.1    Klutts, J.S.2    Wang, Z.3    Doering, T.L.4    Azadi, P.5
  • 14
    • 79251526150 scopus 로고    scopus 로고
    • Glucuronoxylomannan, galactoxylomannan, and mannoprotein occupy spatially separate and discrete regions in the capsule of Cryptococcus neoformans
    • Jesus MD, Nicola AM, Chow SK, Lee IR, Nong S, Specht CA, Levitz SM, Casadevall A. 2010. Glucuronoxylomannan, galactoxylomannan, and mannoprotein occupy spatially separate and discrete regions in the capsule of Cryptococcus neoformans. Virulence 1:500-508. http://dx.doi.org/10.4161/viru.1.6.13451.
    • (2010) Virulence , vol.1 , pp. 500-508
    • Jesus, M.D.1    Nicola, A.M.2    Chow, S.K.3    Lee, I.R.4    Nong, S.5    Specht, C.A.6    Levitz, S.M.7    Casadevall, A.8
  • 15
    • 84872007673 scopus 로고    scopus 로고
    • In good company: Association between fungal glycans generates molecular complexes with unique functions
    • Rodrigues ML, Nimrichter L. 2012. In good company: association between fungal glycans generates molecular complexes with unique functions. Frontiers Microbiol 3:249.
    • (2012) Frontiers Microbiol , vol.3 , pp. 249
    • Rodrigues, M.L.1    Nimrichter, L.2
  • 16
    • 84863702088 scopus 로고    scopus 로고
    • The Cryptococcus neoformans capsule: A sword and a shield
    • O’Meara TR, Alspaugh JA. 2012. The Cryptococcus neoformans capsule: a sword and a shield. Clin Microbiol Rev 25:387-408. http://dx.doi.org/10.1128/CMR.00001-12.
    • (2012) Clin Microbiol Rev , vol.25 , pp. 387-408
    • O’Meara, T.R.1    Alspaugh, J.A.2
  • 17
    • 0028321560 scopus 로고
    • Complementation of a capsuledeficient mutation of Cryptococcus neoformans restores its virulence
    • Chang YC, Kwon-Chung KJ. 1994. Complementation of a capsuledeficient mutation of Cryptococcus neoformans restores its virulence. Mol Cell Biol 14:4912-4919. http://dx.doi.org/10.1128/MCB.14.7.4912.
    • (1994) Mol Cell Biol , vol.14 , pp. 4912-4919
    • Chang, Y.C.1    Kwon-Chung, K.J.2
  • 18
    • 0032694180 scopus 로고    scopus 로고
    • Pathogenicity of Cryptococcus neoformans: Virulence factors and immunological mechanisms
    • Rodrigues ML, Alviano CS, Travassos LR. 1999. Pathogenicity of Cryptococcus neoformans: virulence factors and immunological mechanisms. Microbes Infect 1:293-301. http://dx.doi.org/10.1016/S1286-4579(99)80025-2.
    • (1999) Microbes Infect , vol.1 , pp. 293-301
    • Rodrigues, M.L.1    Alviano, C.S.2    Travassos, L.R.3
  • 20
    • 33644829755 scopus 로고    scopus 로고
    • Cryptococcus neoformans capsular polysaccharide component galactoxylomannan induces apoptosis of human T-cells through activation of caspase-8
    • Pericolini E, Cenci E, Monari C, De Jesus M, Bistoni F, Casadevall A, Vecchiarelli A. 2006. Cryptococcus neoformans capsular polysaccharide component galactoxylomannan induces apoptosis of human T-cells through activation of caspase-8. Cell Microbiol 8:267-275. http://dx.doi.org/10.1111/j.1462-5822.2005.00619.x.
    • (2006) Cell Microbiol , vol.8 , pp. 267-275
    • Pericolini, E.1    Cenci, E.2    Monari, C.3    De Jesus, M.4    Bistoni, F.5    Casadevall, A.6    Vecchiarelli, A.7
  • 21
    • 84860564696 scopus 로고    scopus 로고
    • Capsular material of Cryptococcus neoformans: Virulence and much more
    • Vecchiarelli A, Monari C. 2012. Capsular material of Cryptococcus neoformans: virulence and much more. Mycopathologia 173:375-386. http://dx.doi.org/10.1007/s11046-011-9513-8.
    • (2012) Mycopathologia , vol.173 , pp. 375-386
    • Vecchiarelli, A.1    Monari, C.2
  • 22
    • 84923118876 scopus 로고    scopus 로고
    • Cryptococcus neoformans induces antimicrobial responses and behaves as a facultative intracellular pathogen in the non mammalian model Galleria mellonella
    • Trevijano-Contador N, Herrero-Fernandez I, Garcia-Barbazan I, Scorzoni L, Rueda C, Rossi SA, Garcia-Rodas R, Zaragoza O. 2015. Cryptococcus neoformans induces antimicrobial responses and behaves as a facultative intracellular pathogen in the non mammalian model Galleria mellonella. Virulence 6:66-74. http://dx.doi.org/10.4161/21505594.2014.986412.
    • (2015) Virulence , vol.6 , pp. 66-74
    • Trevijano-Contador, N.1    Herrero-Fernandez, I.2    Garcia-Barbazan, I.3    Scorzoni, L.4    Rueda, C.5    Rossi, S.A.6    Garcia-Rodas, R.7    Zaragoza, O.8
  • 23
    • 65349164198 scopus 로고    scopus 로고
    • The outcome of Cryptococcus neoformans intracellular pathogenesis in human monocytes
    • Alvarez M, Burn T, Luo Y, Pirofski LA, Casadevall A. 2009. The outcome of Cryptococcus neoformans intracellular pathogenesis in human monocytes. BMC Microbiol 9:51. http://dx.doi.org/10.1186/1471-2180-9-51.
    • (2009) BMC Microbiol , vol.9 , pp. 51
    • Alvarez, M.1    Burn, T.2    Luo, Y.3    Pirofski, L.A.4    Casadevall, A.5
  • 26
    • 33644863612 scopus 로고    scopus 로고
    • The physical properties of the capsular polysaccharides from Cryptococcus neoformans suggest features for capsule construction
    • McFadden DC, De Jesus M, Casadevall A. 2006. The physical properties of the capsular polysaccharides from Cryptococcus neoformans suggest features for capsule construction. J Biol Chem 281:1868-1875. http://dx.doi.org/10.1074/jbc.M509465200.
    • (2006) J Biol Chem , vol.281 , pp. 1868-1875
    • McFadden, D.C.1    De Jesus, M.2    Casadevall, A.3
  • 27
    • 79551656118 scopus 로고    scopus 로고
    • Evidence for branching in cryptococcal capsular polysaccharides and consequences on its biological activity
    • Cordero RJ, Frases S, Guimaraes AJ, Rivera J, Casadevall A. 2011. Evidence for branching in cryptococcal capsular polysaccharides and consequences on its biological activity. Mol Microbiol 79:1101-1117. http://dx.doi.org/10.1111/j.1365-2958.2010.07511.x.
    • (2011) Mol Microbiol , vol.79 , pp. 1101-1117
    • Cordero, R.J.1    Frases, S.2    Guimaraes, A.J.3    Rivera, J.4    Casadevall, A.5
  • 28
    • 0025053195 scopus 로고
    • Side group addition by xylosyltransferase and glucuronyltransferase in biosynthesis of capsular polysaccharide in Cryptococcus neoformans
    • White CW, Cherniak R, Jacobson ES. 1990. Side group addition by xylosyltransferase and glucuronyltransferase in biosynthesis of capsular polysaccharide in Cryptococcus neoformans. J Med Vet Mycol 28:289-301. http://dx.doi.org/10.1080/02681219080000381.
    • (1990) J Med Vet Mycol , vol.28 , pp. 289-301
    • White, C.W.1    Cherniak, R.2    Jacobson, E.S.3
  • 29
    • 51649096180 scopus 로고    scopus 로고
    • β1,2-Xylosyltransferase Cxt1p is solely responsible for xylose incorporation into Cryptococcus neoformans glycosphingolipids
    • Castle SA, Owuor EA, Thompson SH, Garnsey MR, Klutts JS, Doering TL, Levery SB. 2008. β1,2-Xylosyltransferase Cxt1p is solely responsible for xylose incorporation into Cryptococcus neoformans glycosphingolipids. Eukaryot Cell 7:1611-1615. http://dx.doi.org/10.1128/EC.00458-07.
    • (2008) Eukaryot Cell , vol.7 , pp. 1611-1615
    • Castle, S.A.1    Owuor, E.A.2    Thompson, S.H.3    Garnsey, M.R.4    Klutts, J.S.5    Doering, T.L.6    Levery, S.B.7
  • 30
    • 47249139951 scopus 로고    scopus 로고
    • Cryptococcal xylosyltransferase 1 (Cxt1p) from Cryptococcus neoformans plays a direct role in the synthesis of capsule polysaccharides
    • Klutts JS, Doering TL. 2008. Cryptococcal xylosyltransferase 1 (Cxt1p) from Cryptococcus neoformans plays a direct role in the synthesis of capsule polysaccharides. J Biol Chem 283:14327-14334. http://dx.doi.org/10.1074/jbc.M708927200.
    • (2008) J Biol Chem , vol.283 , pp. 14327-14334
    • Klutts, J.S.1    Doering, T.L.2
  • 31
    • 34547122741 scopus 로고    scopus 로고
    • A beta-1,2-xylosyltransferase from Cryptococcus neoformans defines a new family of glycosyltransferases
    • Klutts JS, Levery SB, Doering TL. 2007. A beta-1,2-xylosyltransferase from Cryptococcus neoformans defines a new family of glycosyltransferases. J Biol Chem 282:17890-17899. http://dx.doi.org/10.1074/jbc.M701941200.
    • (2007) J Biol Chem , vol.282 , pp. 17890-17899
    • Klutts, J.S.1    Levery, S.B.2    Doering, T.L.3
  • 32
    • 0032836047 scopus 로고    scopus 로고
    • Isolation, characterization, and localization of a capsule-associated gene, CAP10, of Cryptococcus neoformans
    • Chang YC, Kwon-Chung KJ. 1999. Isolation, characterization, and localization of a capsule-associated gene, CAP10, of Cryptococcus neoformans. J Bacteriol 181:5636-5643.
    • (1999) J Bacteriol , vol.181 , pp. 5636-5643
    • Chang, Y.C.1    Kwon-Chung, K.J.2
  • 33
    • 0029886340 scopus 로고    scopus 로고
    • The second capsule gene of Cryptococcus neoformans, CAP64, is essential for virulence
    • Chang YC, Penoyer LA, KwonChung KJ. 1996. The second capsule gene of Cryptococcus neoformans, CAP64, is essential for virulence. Infect Immun 64:1977-1983.
    • (1996) Infect Immun , vol.64 , pp. 1977-1983
    • Chang, Y.C.1    Penoyer, L.A.2    Kwonchung, K.J.3
  • 34
    • 0031924971 scopus 로고    scopus 로고
    • Isolation of the third capsuleassociated gene, CAP60, required for virulence in Cryptococcus neoformans
    • Chang YC, Kwon-Chung KJ. 1998. Isolation of the third capsuleassociated gene, CAP60, required for virulence in Cryptococcus neoformans. Infect Immun 66:2230-2236.
    • (1998) Infect Immun , vol.66 , pp. 2230-2236
    • Chang, Y.C.1    Kwon-Chung, K.J.2
  • 35
    • 84907131202 scopus 로고
    • Strains of Cryptococcus neoformans with defined capsular phenotypes
    • Jacobson ES, Tingler MJ. 1994. Strains of Cryptococcus neoformans with defined capsular phenotypes. J Med Vet Mycol 32:401-404. http://dx.doi.org/10.1080/02681219480000531.
    • (1994) J Med Vet Mycol , vol.32 , pp. 401-404
    • Jacobson, E.S.1    Tingler, M.J.2
  • 36
    • 84904762012 scopus 로고    scopus 로고
    • Deletion of the CAP10 gene of Cryptococcus neoformans results in a pleiotropic phenotype with changes in expression of virulence factors
    • Tefsen B, Grijpstra J, Ordonez S, Lammers M, van Die I, de Cock H. 2014. Deletion of the CAP10 gene of Cryptococcus neoformans results in a pleiotropic phenotype with changes in expression of virulence factors. Res Microbiol 165:399-410. http://dx.doi.org/10.1016/j.resmic.2014.04.001.
    • (2014) Res Microbiol , vol.165 , pp. 399-410
    • Tefsen, B.1    Grijpstra, J.2    Ordonez, S.3    Lammers, M.4    Van Die, I.5    De Cock, H.6
  • 38
    • 0032852335 scopus 로고    scopus 로고
    • A unique alpha-1,3 mannosyltransferase of the pathogenic fungus Cryptococcus neoformans
    • Doering TL. 1999. A unique alpha-1,3 mannosyltransferase of the pathogenic fungus Cryptococcus neoformans. J Bacteriol 181:5482-5488.
    • (1999) J Bacteriol , vol.181 , pp. 5482-5488
    • Doering, T.L.1
  • 39
    • 0344842282 scopus 로고    scopus 로고
    • An alpha-1,3-mannosyltransferase of Cryptococcus neoformans
    • Sommer U, Liu H, Doering TL. 2003. An alpha-1,3-mannosyltransferase of Cryptococcus neoformans. J Biol Chem 278:47724-47730. http://dx.doi.org/10.1074/jbc.M307223200.
    • (2003) J Biol Chem , vol.278 , pp. 47724-47730
    • Sommer, U.1    Liu, H.2    Doering, T.L.3
  • 40
    • 0017734053 scopus 로고
    • Epidemiologic differences among serotypes of Cryptococcus neoformans
    • Bennett JE, Kwonchung KJ, Howard DH. 1977. Epidemiologic differences among serotypes of Cryptococcus neoformans. Am J Epidemiol 105: 582-586.
    • (1977) Am J Epidemiol , vol.105 , pp. 582-586
    • Bennett, J.E.1    Kwonchung, K.J.2    Howard, D.H.3
  • 41
    • 0030832492 scopus 로고    scopus 로고
    • Melanization affects susceptibility of Cryptococcus neoformans to heat and cold
    • Rosas AL, Casadevall A. 1997. Melanization affects susceptibility of Cryptococcus neoformans to heat and cold. FEMS Microbiol Lett 153: 265-272. http://dx.doi.org/10.1016/S0378-1097(97)00239-5.
    • (1997) FEMS Microbiol Lett , vol.153 , pp. 265-272
    • Rosas, A.L.1    Casadevall, A.2
  • 42
    • 80053071743 scopus 로고    scopus 로고
    • Protection of melanized Cryptococcus neoformans from lethal dose gamma irradiation involves changes in melanin’s chemical structure and paramagnetism
    • Khajo A, Bryan RA, Friedman M, Burger RM, Levitsky Y, Casadevall A, Magliozzo RS, Dadachova E. 2011. Protection of melanized Cryptococcus neoformans from lethal dose gamma irradiation involves changes in melanin’s chemical structure and paramagnetism. PLoS One 6:e25092. http://dx.doi.org/10.1371/journal.pone.0025092.
    • (2011) Plos One , vol.6
    • Khajo, A.1    Bryan, R.A.2    Friedman, M.3    Burger, R.M.4    Levitsky, Y.5    Casadevall, A.6    Magliozzo, R.S.7    Dadachova, E.8
  • 43
    • 0015421503 scopus 로고
    • Production of diagnostic pigment by phenoloxidase activity of Cryptococcus neoformans
    • Shaw CE, Kapica L. 1972. Production of diagnostic pigment by phenoloxidase activity of Cryptococcus neoformans. Appl Microbiol 24:824-830.
    • (1972) Appl Microbiol , vol.24 , pp. 824-830
    • Shaw, C.E.1    Kapica, L.2
  • 44
    • 0029883404 scopus 로고    scopus 로고
    • Melanin, melanin “ghosts,” and melanin composition in Cryptococcus neoformans
    • Wang Y, Aisen P, Casadevall A. 1996. Melanin, melanin “ghosts,” and melanin composition in Cryptococcus neoformans. Infect Immun 64: 2420-2424.
    • (1996) Infect Immun , vol.64 , pp. 2420-2424
    • Wang, Y.1    Aisen, P.2    Casadevall, A.3
  • 45
    • 0028069606 scopus 로고
    • Biochemical and molecular characterization of the diphenol oxidase of Cryptococcus neoformans—identification as a laccase
    • Williamson PR. 1994. Biochemical and molecular characterization of the diphenol oxidase of Cryptococcus neoformans—identification as a laccase. J Bacteriol 176:656-664.
    • (1994) J Bacteriol , vol.176 , pp. 656-664
    • Williamson, P.R.1
  • 46
    • 0027491089 scopus 로고
    • Characterization of a phenol oxidase from Cryptococcus neoformans var. Neoformans
    • Ikeda R, Shinoda T, Morita T, Jacobson ES. 1993. Characterization of a phenol oxidase from Cryptococcus neoformans var. neoformans. Microbiol Immunol 37:759-764. http://dx.doi.org/10.1111/j.1348-0421.1993.tb01702.x.
    • (1993) Microbiol Immunol , vol.37 , pp. 759-764
    • Ikeda, R.1    Shinoda, T.2    Morita, T.3    Jacobson, E.S.4
  • 47
    • 0016835476 scopus 로고
    • Pigment production by Cryptococcus neoformans from para- and ortho-diphenols: Effect of the nitrogen source
    • Chaskes S, Tyndall RL. 1975. Pigment production by Cryptococcus neoformans from para- and ortho-diphenols: effect of the nitrogen source. J Clin Microbiol 1:509-514.
    • (1975) J Clin Microbiol , vol.1 , pp. 509-514
    • Chaskes, S.1    Tyndall, R.L.2
  • 48
    • 0018854740 scopus 로고
    • Esculinbased medium for isolation and identification of Cryptococcus neoformans
    • Edberg SC, Chaskes SJ, Alture-Werber E, Singer JM. 1980. Esculinbased medium for isolation and identification of Cryptococcus neoformans. J Clin Microbiol 12:332-335.
    • (1980) J Clin Microbiol , vol.12 , pp. 332-335
    • Edberg, S.C.1    Chaskes, S.J.2    Alture-Werber, E.3    Singer, J.M.4
  • 49
    • 0021067203 scopus 로고
    • Utilization of indole compounds by Cryptococcus neoformans to produce a melanin-like pigment
    • Kwon-Chung KJ, Tom WK, Costa JL. 1983. Utilization of indole compounds by Cryptococcus neoformans to produce a melanin-like pigment. J Clin Microbiol 18:1419-1421.
    • (1983) J Clin Microbiol , vol.18 , pp. 1419-1421
    • Kwon-Chung, K.J.1    Tom, W.K.2    Costa, J.L.3
  • 50
    • 0020264515 scopus 로고
    • Biochemical studies of phenoloxidase and utilization of catecholamines in Cryptococcus neoformans
    • Polacheck I, Hearing VJ, Kwon-Chung KJ. 1982. Biochemical studies of phenoloxidase and utilization of catecholamines in Cryptococcus neoformans. J Bacteriol 150:1212-1220.
    • (1982) J Bacteriol , vol.150 , pp. 1212-1220
    • Polacheck, I.1    Hearing, V.J.2    Kwon-Chung, K.J.3
  • 51
    • 0025002652 scopus 로고
    • Catecholamines and virulence of Cryptococcus neoformans
    • Polacheck I, Platt Y, Aronovitch J. 1990. Catecholamines and virulence of Cryptococcus neoformans. Infect Immun 58:2919-2922.
    • (1990) Infect Immun , vol.58 , pp. 2919-2922
    • Polacheck, I.1    Platt, Y.2    Aronovitch, J.3
  • 52
    • 0015117754 scopus 로고
    • Pigment production of Cryptococcus neoformans grown with extracts of Guizotia abyssinica
    • Strachan AA, Yu RJ, Blank F. 1971. Pigment production of Cryptococcus neoformans grown with extracts of Guizotia abyssinica. Appl Microbiol 22:478-479.
    • (1971) Appl Microbiol , vol.22 , pp. 478-479
    • Strachan, A.A.1    Yu, R.J.2    Blank, F.3
  • 53
    • 0017707881 scopus 로고
    • Evaluation of a caffeic acidferric citrate test for rapid identification of Cryptococcus neoformans
    • Wang HS, Zeimis RT, Roberts GD. 1977. Evaluation of a caffeic acidferric citrate test for rapid identification of Cryptococcus neoformans. J Clin Microbiol 6:445-449.
    • (1977) J Clin Microbiol , vol.6 , pp. 445-449
    • Wang, H.S.1    Zeimis, R.T.2    Roberts, G.D.3
  • 54
    • 0029813941 scopus 로고    scopus 로고
    • Discordant regulation of phenoloxidase and capsular polysaccharide in Cryptococcus neoformans
    • Jacobson ES, Compton GM. 1996. Discordant regulation of phenoloxidase and capsular polysaccharide in Cryptococcus neoformans. J Med Vet Mycol 34:289-291. http://dx.doi.org/10.1080/02681219680000491.
    • (1996) J Med Vet Mycol , vol.34 , pp. 289-291
    • Jacobson, E.S.1    Compton, G.M.2
  • 55
    • 13744260680 scopus 로고    scopus 로고
    • Distinct stress responses of two functional laccases in Cryptococcus neoformans are revealed in the absence of the thiol-specific antioxidant Tsa1
    • Missall TA, Moran JM, Corbett JA, Lodge JK. 2005. Distinct stress responses of two functional laccases in Cryptococcus neoformans are revealed in the absence of the thiol-specific antioxidant Tsa1. Eukaryot Cell 4:202-208. http://dx.doi.org/10.1128/EC.4.1.202-208.2005.
    • (2005) Eukaryot Cell , vol.4 , pp. 202-208
    • Missall, T.A.1    Moran, J.M.2    Corbett, J.A.3    Lodge, J.K.4
  • 57
    • 4644240769 scopus 로고    scopus 로고
    • Role of laccase in the biology and virulence of Cryptococcus neoformans
    • Zhu X, Williamson PR. 2004. Role of laccase in the biology and virulence of Cryptococcus neoformans. FEMS Yeast Res 5:1-10. http://dx.doi.org/10.1016/j.femsyr.2004.04.004.
    • (2004) FEMS Yeast Res , vol.5 , pp. 1-10
    • Zhu, X.1    Williamson, P.R.2
  • 58
    • 0034867481 scopus 로고    scopus 로고
    • Laccase of Cryptococcus neoformans is a cell wall-associated virulence factor
    • Zhu XD, Gibbons J, Garcia-Rivera J, Casadevall A, Williamson PR. 2001. Laccase of Cryptococcus neoformans is a cell wall-associated virulence factor. Infect Immun 69:5589-5596. http://dx.doi.org/10.1128/IAI.69.9.5589-5596.2001.
    • (2001) Infect Immun , vol.69 , pp. 5589-5596
    • Zhu, X.D.1    Gibbons, J.2    Garcia-Rivera, J.3    Casadevall, A.4    Williamson, P.R.5
  • 59
    • 0029839056 scopus 로고    scopus 로고
    • Effect of the laccase gene CNLAC1, on virulence of Cryptococcus neoformans
    • Salas SD, Bennett JE, Kwon-Chung KJ, Perfect JR, Williamson PR. 1996. Effect of the laccase gene CNLAC1, on virulence of Cryptococcus neoformans. J Exp Med 184:377-386. http://dx.doi.org/10.1084/jem.184.2.377.
    • (1996) J Exp Med , vol.184 , pp. 377-386
    • Salas, S.D.1    Bennett, J.E.2    Kwon-Chung, K.J.3    Perfect, J.R.4    Williamson, P.R.5
  • 60
    • 0028356443 scopus 로고
    • Susceptibility of melanized and nonmelanized Cryptococcus neoformans to nitrogen- and oxygen-derived oxidants
    • Wang Y, Casadevall A. 1994. Susceptibility of melanized and nonmelanized Cryptococcus neoformans to nitrogen- and oxygen-derived oxidants. Infect Immun 62:3004-3007.
    • (1994) Infect Immun , vol.62 , pp. 3004-3007
    • Wang, Y.1    Casadevall, A.2
  • 61
    • 0029131284 scopus 로고
    • Cryptococcus neoformans melanin and virulence: Mechanism of action
    • Wang Y, Aisen P, Casadevall A. 1995. Cryptococcus neoformans melanin and virulence: mechanism of action. Infect Immun 63:3131-3136.
    • (1995) Infect Immun , vol.63 , pp. 3131-3136
    • Wang, Y.1    Aisen, P.2    Casadevall, A.3
  • 62
    • 0027384213 scopus 로고
    • Antioxidant function of fungal melanin
    • Jacobson ES, Tinnell SB. 1993. Antioxidant function of fungal melanin. J Bacteriol 175:7102-7104.
    • (1993) J Bacteriol , vol.175 , pp. 7102-7104
    • Jacobson, E.S.1    Tinnell, S.B.2
  • 63
    • 0036840642 scopus 로고    scopus 로고
    • Melanization of Cryptococcus neoformans and Histoplasma capsulatum reduces their susceptibilities to amphotericin B and caspofungin
    • van Duin D, Casadevall A, Nosanchuk JD. 2002. Melanization of Cryptococcus neoformans and Histoplasma capsulatum reduces their susceptibilities to amphotericin B and caspofungin. Antimicrob Agents Chemother 46:3394-3400. http://dx.doi.org/10.1128/AAC.46.11.3394-3400.2002.
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 3394-3400
    • Van Duin, D.1    Casadevall, A.2    Nosanchuk, J.D.3
  • 64
    • 0037270150 scopus 로고    scopus 로고
    • Effects of melanin upon susceptibility of Cryptococcus to antifungals
    • Ikeda R, Sugita T, Jacobson ES, Shinoda T. 2003. Effects of melanin upon susceptibility of Cryptococcus to antifungals. Microbiol Immunol 47:271-277. http://dx.doi.org/10.1111/j.1348-0421.2003.tb03395.x.
    • (2003) Microbiol Immunol , vol.47 , pp. 271-277
    • Ikeda, R.1    Sugita, T.2    Jacobson, E.S.3    Shinoda, T.4
  • 65
    • 0028131885 scopus 로고
    • Growth of Cryptococcus neoformans in presence of L-dopa decreases its susceptibility to amphotericin B
    • Wang YL, Casadevall A. 1994. Growth of Cryptococcus neoformans in presence of L-dopa decreases its susceptibility to amphotericin B. Antimicrob Agents Chemother 38:2648-2650. http://dx.doi.org/10.1128/AAC.38.11.2648.
    • (1994) Antimicrob Agents Chemother , vol.38 , pp. 2648-2650
    • Wang, Y.L.1    Casadevall, A.2
  • 66
    • 34447118987 scopus 로고    scopus 로고
    • Mycoparasitism studies of Trichoderma harzianum strains against Rhizoctonia solani: Evaluation of coiling and hydrolytic enzyme production
    • Almeida FB, Cerqueira FM, Silva Rdo N, Ulhoa CJ, Lima AL. 2007. Mycoparasitism studies of Trichoderma harzianum strains against Rhizoctonia solani: evaluation of coiling and hydrolytic enzyme production. Biotechnol Lett 29:1189-1193. http://dx.doi.org/10.1007/s10529-007-9372-z.
    • (2007) Biotechnol Lett , vol.29 , pp. 1189-1193
    • Almeida, F.B.1    Cerqueira, F.M.2    Silva Rdo, N.3    Ulhoa, C.J.4    Lima, A.L.5
  • 67
    • 76149096474 scopus 로고    scopus 로고
    • Paracoccin from Paracoccidioides brasiliensis; purification through affinity with chitin and identification of N-acetyl-beta-Dglucosaminidase activity
    • Dos Reis Almeida FB, de Oliveira LL, de Sousa MV, Barreira MCR, Hanna ES. 2010. Paracoccin from Paracoccidioides brasiliensis; purification through affinity with chitin and identification of N-acetyl-beta-Dglucosaminidase activity. Yeast 27:67-76.
    • (2010) Yeast , vol.27 , pp. 67-76
    • Dos Reis Almeida, F.B.1    De Oliveira, L.L.2    De Sousa, M.V.3    Barreira, M.4    Hanna, E.S.5
  • 68
    • 84155178203 scopus 로고    scopus 로고
    • Influence of N-glycosylation on the morphogenesis and growth of Paracoccidioides brasiliensis and on the biological activities of yeast proteins
    • Dos Reis Almeida FB, Carvalho FC, Mariano VS, Alegre ACP, Silva RD, Hanna ES, Roque-Barreira MC. 2011. Influence of N-glycosylation on the morphogenesis and growth of Paracoccidioides brasiliensis and on the biological activities of yeast proteins. PLoS One 6:e29216. http://dx.doi.org/10.1371/journal.pone.0029216.
    • (2011) Plos One , vol.6
    • Dos Reis Almeida, F.B.1    Carvalho, F.C.2    Mariano, V.S.3    Alegre, A.4    Silva, R.D.5    Hanna, E.S.6    Roque-Barreira, M.C.7
  • 69
    • 84891902448 scopus 로고    scopus 로고
    • Alpha-(1,4)-Amylase, but not alpha- and beta-(1,3)-glucanases, may be responsible for the impaired growth and morphogenesis of Paracoccidioides brasiliensis induced by N-glycosylation inhibition
    • Dos Reis Almeida FB, Pigosso LL, de Lima Damasio AR, Monteiro VN, de Almeida Soares CM, Silva RN, Roque-Barreira MC. 2014. Alpha-(1,4)-Amylase, but not alpha- and beta-(1,3)-glucanases, may be responsible for the impaired growth and morphogenesis of Paracoccidioides brasiliensis induced by N-glycosylation inhibition. Yeast 31:1-11. http://dx.doi.org/10.1002/yea.2983.
    • (2014) Yeast , vol.31 , pp. 1-11
    • Dos Reis Almeida, F.B.1    Pigosso, L.L.2    De Lima Damasio, A.R.3    Monteiro, V.N.4    De Almeida Soares, C.M.5    Silva, R.N.6    Roque-Barreira, M.C.7
  • 70
    • 1942490350 scopus 로고
    • Cryptococcus neoformans in bird droppings in London
    • Partridge BM, Winner HI. 1965. Cryptococcus neoformans in bird droppings in London. Lancet i:1060-1061.
    • (1965) Lancet I , pp. 1060-1061
    • Partridge, B.M.1    Winner, H.I.2
  • 71
    • 0014349414 scopus 로고
    • Factors that determine the growth of Cryptococcus neoformans in avian excreta
    • Walter JE, Yee RB. 1968. Factors that determine the growth of Cryptococcus neoformans in avian excreta. Am J Epidemiol 88:445-450.
    • (1968) Am J Epidemiol , vol.88 , pp. 445-450
    • Walter, J.E.1    Yee, R.B.2
  • 73
    • 0014635358 scopus 로고
    • Primary isolation medium for Cryptococcus neoformans
    • Vogel RA. 1969. Primary isolation medium for Cryptococcus neoformans. Appl Microbiol 18:1100.
    • (1969) Appl Microbiol , vol.18 , pp. 1100
    • Vogel, R.A.1
  • 74
    • 0018712943 scopus 로고
    • Rapid selective urease test for presumptive identification of Cryptococcus neoformans
    • Zimmer BL, Roberts GD. 1979. Rapid selective urease test for presumptive identification of Cryptococcus neoformans. J Clin Microbiol 10:380-381.
    • (1979) J Clin Microbiol , vol.10 , pp. 380-381
    • Zimmer, B.L.1    Roberts, G.D.2
  • 75
    • 0033971038 scopus 로고    scopus 로고
    • Urease as a virulence factor in experimental cryptococcosis
    • Cox GM, Mukherjee J, Cole GT, Casadevall A, Perfect JR. 2000. Urease as a virulence factor in experimental cryptococcosis. Infect Immun 68: 443-448. http://dx.doi.org/10.1128/IAI.68.2.443-448.2000.
    • (2000) Infect Immun , vol.68 , pp. 443-448
    • Cox, G.M.1    Mukherjee, J.2    Cole, G.T.3    Casadevall, A.4    Perfect, J.R.5
  • 76
    • 1942533402 scopus 로고    scopus 로고
    • Urease expression by Cryptococcus neoformans promotes microvascular sequestration, thereby enhancing central nervous system invasion
    • Olszewski MA, Noverr MC, Chen GH, Toews GB, Cox GM, Perfect JR, Huffnagle GB. 2004. Urease expression by Cryptococcus neoformans promotes microvascular sequestration, thereby enhancing central nervous system invasion. Am J Pathol 164:1761-1771. http://dx.doi.org/10.1016/S0002-9440(10)63734-0.
    • (2004) Am J Pathol , vol.164 , pp. 1761-1771
    • Olszewski, M.A.1    Noverr, M.C.2    Chen, G.H.3    Toews, G.B.4    Cox, G.M.5    Perfect, J.R.6    Huffnagle, G.B.7
  • 77
    • 84907132913 scopus 로고
    • Cryptococcosis produced by a urease negative strain of Cryptococcus neoformans
    • Bava AJ, Negroni R, Bianchi M. 1993. Cryptococcosis produced by a urease negative strain of Cryptococcus neoformans. J Med Vet Mycol 31: 87-89. http://dx.doi.org/10.1080/02681219380000091.
    • (1993) J Med Vet Mycol , vol.31 , pp. 87-89
    • Bava, A.J.1    Negroni, R.2    Bianchi, M.3
  • 78
    • 0023764480 scopus 로고
    • Disseminated infection caused by urease-negative Cryptococcus neoformans
    • Ruane PJ, Walker LJ, George WL. 1988. Disseminated infection caused by urease-negative Cryptococcus neoformans. J Clin Microbiol 26:2224-2225.
    • (1988) J Clin Microbiol , vol.26 , pp. 2224-2225
    • Ruane, P.J.1    Walker, L.J.2    George, W.L.3
  • 79
    • 0014603060 scopus 로고
    • Extracellular deoxyribonuclease production by yeasts
    • Cazin J, Jr, Kozel TR, Lupan DM, Burt WR. 1969. Extracellular deoxyribonuclease production by yeasts. J Bacteriol 100:760-762.
    • (1969) J Bacteriol , vol.100 , pp. 760-762
    • Cazin, J.1    Kozel, T.R.2    Lupan, D.M.3    Burt, W.R.4
  • 81
    • 77953689110 scopus 로고    scopus 로고
    • Extracellular DNase activity of Cryptococcus neoformans and Cryptococcus gattii
    • Sanchez M, Colom F. 2010. Extracellular DNase activity of Cryptococcus neoformans and Cryptococcus gattii. Rev Iberoam Micol 27:10-13. http://dx.doi.org/10.1016/j.riam.2009.11.004.
    • (2010) Rev Iberoam Micol , vol.27 , pp. 10-13
    • Sanchez, M.1    Colom, F.2
  • 82
    • 0029053451 scopus 로고
    • Superoxide radical and superoxide dismutases
    • Fridovich I. 1995. Superoxide radical and superoxide dismutases. Annu Rev Biochem 64:97-112. http://dx.doi.org/10.1146/annurev.bi.64.070195.000525.
    • (1995) Annu Rev Biochem , vol.64 , pp. 97-112
    • Fridovich, I.1
  • 83
    • 0031018901 scopus 로고    scopus 로고
    • Biochemical comparison of the Cu,Zn superoxide dismutases of Cryptococcus neoformans var. Neoformans and Cryptococcus neoformans var. Gattii
    • Hamilton AJ, Holdom MD. 1997. Biochemical comparison of the Cu,Zn superoxide dismutases of Cryptococcus neoformans var. neoformans and Cryptococcus neoformans var. gattii. Infect Immun 65:488-494.
    • (1997) Infect Immun , vol.65 , pp. 488-494
    • Hamilton, A.J.1    Holdom, M.D.2
  • 84
    • 0029096167 scopus 로고
    • Superoxide dismutase of Cryptococcus neoformans: Purification and characterization
    • Tesfa-Selase F, Hay RJ. 1995. Superoxide dismutase of Cryptococcus neoformans: purification and characterization. J Med Vet Mycol 33:253-259. http://dx.doi.org/10.1080/02681219580000511.
    • (1995) J Med Vet Mycol , vol.33 , pp. 253-259
    • Tesfa-Selase, F.1    Hay, R.J.2
  • 85
    • 13744258600 scopus 로고    scopus 로고
    • Cryptococcus neoformans mitochondrial superoxide dismutase: An essential link between antioxidant function and high-temperature growth
    • Giles SS, Batinic-Haberle I, Perfect JR, Cox GM. 2005. Cryptococcus neoformans mitochondrial superoxide dismutase: an essential link between antioxidant function and high-temperature growth. Eukaryot Cell 4:46-54. http://dx.doi.org/10.1128/EC.4.1.46-54.2005.
    • (2005) Eukaryot Cell , vol.4 , pp. 46-54
    • Giles, S.S.1    Batinic-Haberle, I.2    Perfect, J.R.3    Cox, G.M.4
  • 86
    • 0345268706 scopus 로고    scopus 로고
    • Characterization of Cu,Zn superoxide dismutase (SOD1) gene knockout mutant of Cryptococcus neoformans var. Gattii: Role in biology and virulence
    • Narasipura SD, Ault JG, Behr MJ, Chaturvedi V, Chaturvedi S. 2003. Characterization of Cu,Zn superoxide dismutase (SOD1) gene knockout mutant of Cryptococcus neoformans var. gattii: role in biology and virulence. Mol Microbiol 47:1681-1694.
    • (2003) Mol Microbiol , vol.47 , pp. 1681-1694
    • Narasipura, S.D.1    Ault, J.G.2    Behr, M.J.3    Chaturvedi, V.4    Chaturvedi, S.5
  • 87
    • 15944368964 scopus 로고    scopus 로고
    • Characterization of Cryptococcus neoformans variety gattii SOD2 reveals distinct roles of the two superoxide dismutases in fungal biology and virulence
    • Narasipura SD, Chaturvedi V, Chaturvedi S. 2005. Characterization of Cryptococcus neoformans variety gattii SOD2 reveals distinct roles of the two superoxide dismutases in fungal biology and virulence. Mol Microbiol 55:1782-1800. http://dx.doi.org/10.1111/j.1365-2958.2005.04503.x.
    • (2005) Mol Microbiol , vol.55 , pp. 1782-1800
    • Narasipura, S.D.1    Chaturvedi, V.2    Chaturvedi, S.3
  • 88
    • 33645050376 scopus 로고    scopus 로고
    • Lipid rafts in Cryptococcus neoformans concentrate the virulence determinants phospholipase B1 and Cu/Zn superoxide dismutase
    • Siafakas AR, Wright LC, Sorrell TC, Djordjevic JT. 2006. Lipid rafts in Cryptococcus neoformans concentrate the virulence determinants phospholipase B1 and Cu/Zn superoxide dismutase. Eukaryot Cell 5:488-498. http://dx.doi.org/10.1128/EC.5.3.488-498.2006.
    • (2006) Eukaryot Cell , vol.5 , pp. 488-498
    • Siafakas, A.R.1    Wright, L.C.2    Sorrell, T.C.3    Djordjevic, J.T.4
  • 89
    • 0037218164 scopus 로고    scopus 로고
    • Superoxide dismutase influences the virulen ce of Cryptococcus neoformans by affecting growth within macro-phages
    • Cox GM, Harrison TS, McDade HC, Taborda CP, Heinrich G, Casadevall A, Perfect JR. 2003. Superoxide dismutase influences the virulen ce of Cryptococcus neoformans by affecting growth within macro-phages. Infect Immun 71:173-180. http://dx.doi.org/10.1128/IAI.71.1.173-180.2003.
    • (2003) Infect Immun , vol.71 , pp. 173-180
    • Cox, G.M.1    Harrison, T.S.2    McDade, H.C.3    Taborda, C.P.4    Heinrich, G.5    Casadevall, A.6    Perfect, J.R.7
  • 90
    • 0028048761 scopus 로고
    • Relationship between superoxide- dismutase and melanin in a pathogenic fungus
    • Jacobson ES, Jenkins ND, Todd JM. 1994. Relationship between superoxide- dismutase and melanin in a pathogenic fungus. Infect Immun 62:4085-4086.
    • (1994) Infect Immun , vol.62 , pp. 4085-4086
    • Jacobson, E.S.1    Jenkins, N.D.2    Todd, J.M.3
  • 91
    • 0031019618 scopus 로고    scopus 로고
    • Phospholipase activity in Cryptococcus neoformans: A new virulence factor?
    • Chen SC, Muller M, Zhou JZ, Wright LC, Sorrell TC. 1997. Phospholipase activity in Cryptococcus neoformans: a new virulence factor? J Infect Dis 175:414-420. http://dx.doi.org/10.1093/infdis/175.2.414.
    • (1997) J Infect Dis , vol.175 , pp. 414-420
    • Chen, S.C.1    Muller, M.2    Zhou, J.Z.3    Wright, L.C.4    Sorrell, T.C.5
  • 92
    • 0031020229 scopus 로고    scopus 로고
    • Identification of extracellular phospholipase B, lysophospholipase, and acyltransferase produced by Cryptococcus neoformans
    • Chen SCA, Wright LC, Santangelo RT, Muller M, Moran VR, Kuchel PW, Sorrell TC. 1997. Identification of extracellular phospholipase B, lysophospholipase, and acyltransferase produced by Cryptococcus neoformans. Infect Immun 65:405-411.
    • (1997) Infect Immun , vol.65 , pp. 405-411
    • Chen, S.1    Wright, L.C.2    Santangelo, R.T.3    Muller, M.4    Moran, V.R.5    Kuchel, P.W.6    Sorrell, T.C.7
  • 93
    • 79951581102 scopus 로고    scopus 로고
    • Characterization of inositol phospho-sphingolipid-phospholipase C 1 (Isc1) in Cryptococcus neoformans reveals unique biochemical features
    • Henry J, Guillotte A, Luberto C, Del Poeta M. 2011. Characterization of inositol phospho-sphingolipid-phospholipase C 1 (Isc1) in Cryptococcus neoformans reveals unique biochemical features. FEBS Lett 585:635-640. http://dx.doi.org/10.1016/j.febslet.2011.01.015.
    • (2011) FEBS Lett , vol.585 , pp. 635-640
    • Henry, J.1    Guillotte, A.2    Luberto, C.3    Del Poeta, M.4
  • 94
    • 0021802309 scopus 로고
    • A comparison of phospholipase activity, cellular adherence and pathogenicity of yeasts
    • Barrett-Bee K, Hayes Y, Wilson RG, Ryley JF. 1985. A comparison of phospholipase activity, cellular adherence and pathogenicity of yeasts. J Gen Microbiol 131:1217-1221.
    • (1985) J Gen Microbiol , vol.131 , pp. 1217-1221
    • Barrett-Bee, K.1    Hayes, Y.2    Wilson, R.G.3    Ryley, J.F.4
  • 95
    • 1842431591 scopus 로고    scopus 로고
    • Role of extracellular phospholipases and mononuclear phagocytes in dissemination of cryptococcosis in a murine model
    • Santangelo R, Zoellner H, Sorrell T, Wilson C, Donald C, Djordjevic J, Shounan Y, Wright L. 2004. Role of extracellular phospholipases and mononuclear phagocytes in dissemination of cryptococcosis in a murine model. Infect Immun 72:2229-2239. http://dx.doi.org/10.1128/IAI.72.4.2229-2239.2004.
    • (2004) Infect Immun , vol.72 , pp. 2229-2239
    • Santangelo, R.1    Zoellner, H.2    Sorrell, T.3    Wilson, C.4    Donald, C.5    Djordjevic, J.6    Shounan, Y.7    Wright, L.8
  • 96
    • 0034655753 scopus 로고    scopus 로고
    • Purification and characterization of secretory phospholipase B, lysophospholipase and lysophospholipase/transacylase from a virulent strain of the pathogenic fungus Cryptococcus neoformans
    • Chen SC, Wright LC, Golding JC, Sorrell TC. 2000. Purification and characterization of secretory phospholipase B, lysophospholipase and lysophospholipase/transacylase from a virulent strain of the pathogenic fungus Cryptococcus neoformans. Biochem J 347:431-439. http://dx.doi.org/10.1042/bj3470431.
    • (2000) Biochem J , vol.347 , pp. 431-439
    • Chen, S.C.1    Wright, L.C.2    Golding, J.C.3    Sorrell, T.C.4
  • 97
    • 38049129579 scopus 로고    scopus 로고
    • Cell wall-linked cryptococcal phospholipase B1 is a source of secreted enzyme and a determinant of cell wall integrity
    • Siafakas AR, Sorrell TC, Wright LC, Wilson C, Larsen M, Boadle R, Williamson PR, Djordjevic JT. 2007. Cell wall-linked cryptococcal phospholipase B1 is a source of secreted enzyme and a determinant of cell wall integrity. J Biol Chem 282:37508-37514. http://dx.doi.org/10.1074/jbc.M707913200.
    • (2007) J Biol Chem , vol.282 , pp. 37508-37514
    • Siafakas, A.R.1    Sorrell, T.C.2    Wright, L.C.3    Wilson, C.4    Larsen, M.5    Boadle, R.6    Williamson, P.R.7    Djordjevic, J.T.8
  • 98
    • 33846419540 scopus 로고    scopus 로고
    • Cryptococcal lipid metabolism: Phospholipase B1 is implicated in transcellular metabolism of macrophage-derived lipids
    • Wright LC, Santangelo RM, Ganendren R, Payne J, Djordjevic JT, Sorrell TC. 2007. Cryptococcal lipid metabolism: phospholipase B1 is implicated in transcellular metabolism of macrophage-derived lipids. Eukaryot Cell 6:37-47. http://dx.doi.org/10.1128/EC.00262-06.
    • (2007) Eukaryot Cell , vol.6 , pp. 37-47
    • Wright, L.C.1    Santangelo, R.M.2    Ganendren, R.3    Payne, J.4    Djordjevic, J.T.5    Sorrell, T.C.6
  • 99
    • 0037373354 scopus 로고    scopus 로고
    • Role of PLB1 in pulmonary inflammation and cryptococcal eicosanoid production
    • Noverr MC, Cox GM, Perfect JR, Huffnagle GB. 2003. Role of PLB1 in pulmonary inflammation and cryptococcal eicosanoid production. Infect Immun 71:1538-1547. http://dx.doi.org/10.1128/IAI.71.3.1538-1547.2003.
    • (2003) Infect Immun , vol.71 , pp. 1538-1547
    • Noverr, M.C.1    Cox, G.M.2    Perfect, J.R.3    Huffnagle, G.B.4
  • 100
    • 33748910691 scopus 로고    scopus 로고
    • N-linked glycosylation sites affect secretion of cryptococcal phospholipase B1, irrespective of glycosylphosphatidylinositol anchoring
    • Turner KM, Wright LC, Sorrell TC, Djordjevic JT. 2006. N-linked glycosylation sites affect secretion of cryptococcal phospholipase B1, irrespective of glycosylphosphatidylinositol anchoring. Biochim Biophys Acta 1760:1569-1579. http://dx.doi.org/10.1016/j.bbagen.2006.07.002.
    • (2006) Biochim Biophys Acta , vol.1760 , pp. 1569-1579
    • Turner, K.M.1    Wright, L.C.2    Sorrell, T.C.3    Djordjevic, J.T.4
  • 101
    • 47749156040 scopus 로고    scopus 로고
    • Role and mechanism of phosphatidylinositol- specific phospholipase C in survival and virulence of Cryptococcus neoformans
    • Chayakulkeeree M, Sorrell TC, Siafakas AR, Wilson CF, Pantarat N, Gerik KJ, Boadle R, Djordjevic JT. 2008. Role and mechanism of phosphatidylinositol- specific phospholipase C in survival and virulence of Cryptococcus neoformans. Mol Microbiol 69:809-826. http://dx.doi.org/10.1111/j.1365-2958.2008.06310.x.
    • (2008) Mol Microbiol , vol.69 , pp. 809-826
    • Chayakulkeeree, M.1    Sorrell, T.C.2    Siafakas, A.R.3    Wilson, C.F.4    Pantarat, N.5    Gerik, K.J.6    Boadle, R.7    Djordjevic, J.T.8
  • 102
    • 84875544623 scopus 로고    scopus 로고
    • Phospholipase C of Cryptococcus neoformans regulates homeostasis and virulence by providing inositol trisphosphate as a substrate for Arg1 kinase
    • Lev S, Desmarini D, Li C, Chayakulkeeree M, Traven A, Sorrell TC, Djordjevic JT. 2013. Phospholipase C of Cryptococcus neoformans regulates homeostasis and virulence by providing inositol trisphosphate as a substrate for Arg1 kinase. Infect Immun 81:1245-1255. http://dx.doi.org/10.1128/IAI.01421-12.
    • (2013) Infect Immun , vol.81 , pp. 1245-1255
    • Lev, S.1    Desmarini, D.2    Li, C.3    Chayakulkeeree, M.4    Traven, A.5    Sorrell, T.C.6    Djordjevic, J.T.7
  • 103
    • 0036045812 scopus 로고    scopus 로고
    • Kinase- and phosphatase-anchoring proteins: Harnessing the dynamic duo
    • Bauman AL, Scott JD. 2002. Kinase- and phosphatase-anchoring proteins: harnessing the dynamic duo. Nat Cell Biol 4:E203-E206. http://dx.doi.org/10.1038/ncb0802-e203.
    • (2002) Nat Cell Biol , vol.4
    • Bauman, A.L.1    Scott, J.D.2
  • 104
    • 66849115406 scopus 로고    scopus 로고
    • Targeting protein serine/threonine phosphatases for drug development
    • McConnell JL, Wadzinski BE. 2009. Targeting protein serine/threonine phosphatases for drug development. Mol Pharmacol 75:1249-1261. http://dx.doi.org/10.1124/mol.108.053140.
    • (2009) Mol Pharmacol , vol.75 , pp. 1249-1261
    • McConnell, J.L.1    Wadzinski, B.E.2
  • 107
    • 0022652199 scopus 로고
    • Proteolytic activity of a clinical isolate of Cryptococcus neoformans
    • Brueske CH. 1986. Proteolytic activity of a clinical isolate of Cryptococcus neoformans. J Clin Microbiol 23:631-633.
    • (1986) J Clin Microbiol , vol.23 , pp. 631-633
    • Brueske, C.H.1
  • 108
    • 0029793565 scopus 로고    scopus 로고
    • Extracellular proteinase activity of Cryptococcus neoformans
    • Chen LC, Blank ES, Casadevall A. 1996. Extracellular proteinase activity of Cryptococcus neoformans. Clin Diagn Lab Immunol 3:570-574.
    • (1996) Clin Diagn Lab Immunol , vol.3 , pp. 570-574
    • Chen, L.C.1    Blank, E.S.2    Casadevall, A.3
  • 109
    • 0033881395 scopus 로고    scopus 로고
    • A rapid method for detecting extracellular proteinase activity in Cryptococcus neoformans and a survey of 63 isolates
    • Ruma-Haynes P, Brownlee AG, Sorrell TC. 2000. A rapid method for detecting extracellular proteinase activity in Cryptococcus neoformans and a survey of 63 isolates. J Med Microbiol 49:733-737. http://dx.doi.org/10.1099/0022-1317-49-8-733.
    • (2000) J Med Microbiol , vol.49 , pp. 733-737
    • Ruma-Haynes, P.1    Brownlee, A.G.2    Sorrell, T.C.3
  • 110
    • 1242336854 scopus 로고    scopus 로고
    • Purification and characterization of a 43-kilodalton extracellular serine proteinase from Cryptococcus neoformans
    • Il Yoo J, Lee YS, Song CY, Kim BS. 2004. Purification and characterization of a 43-kilodalton extracellular serine proteinase from Cryptococcus neoformans. J Clin Microbiol 42:722-726. http://dx.doi.org/10.1128/JCM.42.2.722-726.2004.
    • (2004) J Clin Microbiol , vol.42 , pp. 722-726
    • Il Yoo, J.1    Lee, Y.S.2    Song, C.Y.3    Kim, B.S.4
  • 111
    • 34547116868 scopus 로고    scopus 로고
    • Identification and characterization of an aspartyl protease from Cryptococcus neoformans
    • Pinti M, Orsi CF, Gibellini L, Esposito R, Cossarizza A, Blasi E, Peppoloni S, Mussini C. 2007. Identification and characterization of an aspartyl protease from Cryptococcus neoformans. FEBS Lett 581:3882-3886. http://dx.doi.org/10.1016/j.febslet.2007.07.006.
    • (2007) FEBS Lett , vol.581 , pp. 3882-3886
    • Pinti, M.1    Orsi, C.F.2    Gibellini, L.3    Esposito, R.4    Cossarizza, A.5    Blasi, E.6    Peppoloni, S.7    Mussini, C.8
  • 112
    • 0030914029 scopus 로고    scopus 로고
    • Extracellular proteins of Cryptococcus neoformans and host antibody response
    • Chen LC, Pirofski LA, Casadevall A. 1997. Extracellular proteins of Cryptococcus neoformans and host antibody response. Infect Immun 65: 2599-2605.
    • (1997) Infect Immun , vol.65 , pp. 2599-2605
    • Chen, L.C.1    Pirofski, L.A.2    Casadevall, A.3
  • 113
    • 84903978023 scopus 로고    scopus 로고
    • Invasion of the central nervous system by Cryptococcus neoformans requires a secreted fungal metalloprotease
    • Vu K, Tham R, Uhrig JP, Thompson GR, III, Na Pombejra S, Jamklang M, Bautos JM, Gelli A. 2014. Invasion of the central nervous system by Cryptococcus neoformans requires a secreted fungal metalloprotease. MBio 5:e01101-14. http://dx.doi.org/10.1128/mBio.01101-14.
    • (2014) Mbio , vol.5
    • Vu, K.1    Tham, R.2    Uhrig, J.P.3    Thompson, G.R.4    Na Pombejra, S.5    Jamklang, M.6    Bautos, J.M.7    Gelli, A.8
  • 114
    • 0027372019 scopus 로고
    • The gene encoding phosphoribosylaminoimidazole carboxylase (Ade2) is essential for growth of Cryptococcus neoformans in cerebrospinal fluid
    • Perfect JR, Toffaletti DL, Rude TH. 1993. The gene encoding phosphoribosylaminoimidazole carboxylase (Ade2) is essential for growth of Cryptococcus neoformans in cerebrospinal fluid. Infect Immun 61:4446-4451.
    • (1993) Infect Immun , vol.61 , pp. 4446-4451
    • Perfect, J.R.1    Toffaletti, D.L.2    Rude, T.H.3
  • 115
    • 0026563913 scopus 로고
    • Lysine biosynthesis in selected pathogenic fungi—characterization of lysine auxotrophs and the cloned Lys1 gene of Candida albicans
    • Garrad RC, Bhattacharjee JK. 1992. Lysine biosynthesis in selected pathogenic fungi—characterization of lysine auxotrophs and the cloned Lys1 gene of Candida albicans. J Bacteriol 174:7379-7384.
    • (1992) J Bacteriol , vol.174 , pp. 7379-7384
    • Garrad, R.C.1    Bhattacharjee, J.K.2
  • 116
    • 0028000667 scopus 로고
    • Comparison of myristoyl-CoA:Protein N-myristoyltransferases from three pathogenic fungi: Cryptococcus neoformans, Histoplasma capsulatum, and Candida albicans
    • Lodge JK, Johnson RL, Weinberg RA, Gordon JI. 1994. Comparison of myristoyl-CoA:protein N-myristoyltransferases from three pathogenic fungi: Cryptococcus neoformans, Histoplasma capsulatum, and Candida albicans. J Biol Chem 269:2996-3009.
    • (1994) J Biol Chem , vol.269 , pp. 2996-3009
    • Lodge, J.K.1    Johnson, R.L.2    Weinberg, R.A.3    Gordon, J.I.4
  • 117
    • 0028053746 scopus 로고
    • Targeted gene replacement demonstrates that myristoyl-CoA/protein N-myristoyltransferase is essential for viability of Cryptococcus neoformans
    • Lodge JK, Jackson-Machelski E, Toffaletti DL, Perfect JR, Gordon JI. 1994. Targeted gene replacement demonstrates that myristoyl-CoA/protein N-myristoyltransferase is essential for viability of Cryptococcus neoformans. Proc Natl Acad Sci U S A 91:12008-12012. http://dx.doi.org/10.1073/pnas.91.25.12008.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 12008-12012
    • Lodge, J.K.1    Jackson-Machelski, E.2    Toffaletti, D.L.3    Perfect, J.R.4    Gordon, J.I.5
  • 119
    • 0029046535 scopus 로고
    • Resistant P45051A1 activity in azole antifungal tolerant Cryptococcus neoformans from AIDS patients
    • Lamb DC, Corran A, Baldwin BC, Kwon-Chung J, Kelly SL. 1995. Resistant P45051A1 activity in azole antifungal tolerant Cryptococcus neoformans from AIDS patients. FEBS Lett 368:326-330. http://dx.doi.org/10.1016/0014-5793(95)00684-2.
    • (1995) FEBS Lett , vol.368 , pp. 326-330
    • Lamb, D.C.1    Corran, A.2    Baldwin, B.C.3    Kwon-Chung, J.4    Kelly, S.L.5
  • 121
    • 0019190616 scopus 로고
    • Garlic in cryptococcal meningitis: A preliminary report of 21 cases
    • Anonymous
    • Anonymous. 1980. Garlic in cryptococcal meningitis: a preliminary report of 21 cases. Chin Med J (Engl) 93:123-126.
    • (1980) Chin Med J (Engl) , vol.93 , pp. 123-126
  • 122
    • 0029999672 scopus 로고    scopus 로고
    • Fluorescence studies on the molecular action of amphotericin B on susceptible and resistant fungal cells
    • Haynes MP, Chong PLG, Buckley HR, Pieringer RA. 1996. Fluorescence studies on the molecular action of amphotericin B on susceptible and resistant fungal cells. Biochemistry 35:7983-7992. http://dx.doi.org/10.1021/bi952910c.
    • (1996) Biochemistry , vol.35 , pp. 7983-7992
    • Haynes, M.P.1    Chong, P.2    Buckley, H.R.3    Pieringer, R.A.4
  • 124
    • 0027956453 scopus 로고
    • Resistance to amphotericin B associated with defective sterol delta 8¡7 isomerase in a Cryptococcus neoformans strain from an AIDS patient
    • Kelly SL, Lamb DC, Taylor M, Corran AJ, Baldwin BC, Powderly WG. 1994. Resistance to amphotericin B associated with defective sterol delta 8¡7 isomerase in a Cryptococcus neoformans strain from an AIDS patient. FEMS Microbiol Lett 122:39-42. http://dx.doi.org/10.1111/j.1574-6968.1994.tb07140.x.
    • (1994) FEMS Microbiol Lett , vol.122 , pp. 39-42
    • Kelly, S.L.1    Lamb, D.C.2    Taylor, M.3    Corran, A.J.4    Baldwin, B.C.5    Powderly, W.G.6
  • 126
    • 33749242244 scopus 로고    scopus 로고
    • The cryptococcal enzyme inositol phosphosphingolipid-phospholipase C confers resistance to the antifungal effects of macrophages and promotes fungal dissemination to the central nervous system
    • Shea JM, Kechichian TB, Luberto C, Del Poeta M. 2006. The cryptococcal enzyme inositol phosphosphingolipid-phospholipase C confers resistance to the antifungal effects of macrophages and promotes fungal dissemination to the central nervous system. Infect Immun 74:5977-5988. http://dx.doi.org/10.1128/IAI.00768-06.
    • (2006) Infect Immun , vol.74 , pp. 5977-5988
    • Shea, J.M.1    Kechichian, T.B.2    Luberto, C.3    Del Poeta, M.4
  • 127
    • 84893767052 scopus 로고    scopus 로고
    • Synthesis and biological properties of fungal glucosylceramide
    • Del Poeta M, Nimrichter L, Rodrigues ML, Luberto C. 2014. Synthesis and biological properties of fungal glucosylceramide. PLoS Pathog 10: e1003832. http://dx.doi.org/10.1371/journal.ppat.1003832.
    • (2014) Plos Pathog , vol.10
    • Del Poeta, M.1    Nimrichter, L.2    Rodrigues, M.L.3    Luberto, C.4
  • 129
    • 0035313294 scopus 로고    scopus 로고
    • Glyphosate inhibits melanization of Cryptococcus neoformans and prolongs survival of mice after systemic infection
    • Nosanchuk JD, Ovalle R, Casadevall A. 2001. Glyphosate inhibits melanization of Cryptococcus neoformans and prolongs survival of mice after systemic infection. J Infect Dis 183:1093-1099. http://dx.doi.org/10.1086/319272.
    • (2001) J Infect Dis , vol.183 , pp. 1093-1099
    • Nosanchuk, J.D.1    Ovalle, R.2    Casadevall, A.3
  • 130
    • 84880579842 scopus 로고    scopus 로고
    • The nucleoside reverse transcriptase inhibitors, nonnucleoside reverse transcriptase inhibitors, and protease inhibitors in the treatment of HIV infections (AIDS)
    • De Clercq E. 2013. The nucleoside reverse transcriptase inhibitors, nonnucleoside reverse transcriptase inhibitors, and protease inhibitors in the treatment of HIV infections (AIDS). Adv Pharmacol 67:317-358. http://dx.doi.org/10.1016/B978-0-12-405880-4.00009-3.
    • (2013) Adv Pharmacol , vol.67 , pp. 317-358
    • De Clercq, E.1
  • 131
    • 84908642098 scopus 로고    scopus 로고
    • Antiviral strategies against influenza virus: Towards new therapeutic approaches
    • Loregian A, Mercorelli B, Nannetti G, Compagnin C, Palu G. 2014. Antiviral strategies against influenza virus: towards new therapeutic approaches. Cell Mol Life Sci 71:3659-3683. http://dx.doi.org/10.1007/s00018-014-1615-2.
    • (2014) Cell Mol Life Sci , vol.71 , pp. 3659-3683
    • Loregian, A.1    Mercorelli, B.2    Nannetti, G.3    Compagnin, C.4    Palu, G.5
  • 132
    • 0033509027 scopus 로고    scopus 로고
    • In vitro and in vivo anticandidal activity of human immunodeficiency virus protease inhibitors
    • Cassone A, De Bernardis F, Torosantucci A, Tacconelli E, Tumbarello M, Cauda R. 1999. In vitro and in vivo anticandidal activity of human immunodeficiency virus protease inhibitors. J Infect Dis 180:448-453. http://dx.doi.org/10.1086/314871.
    • (1999) J Infect Dis , vol.180 , pp. 448-453
    • Cassone, A.1    De Bernardis, F.2    Torosantucci, A.3    Tacconelli, E.4    Tumbarello, M.5    Cauda, R.6
  • 135
    • 21444455677 scopus 로고    scopus 로고
    • Cryptococcus neoformans resistance to echinocandins: (1,3)beta-glucan synthase activity is sensitive to echinocandins
    • Maligie MA, Selitrennikoff CP. 2005. Cryptococcus neoformans resistance to echinocandins: (1,3)beta-glucan synthase activity is sensitive to echinocandins. Antimicrob Agents Chemother 49:2851-2856. http://dx.doi.org/10.1128/AAC.49.7.2851-2856.2005.
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 2851-2856
    • Maligie, M.A.1    Selitrennikoff, C.P.2
  • 136
    • 0020961628 scopus 로고
    • Contribution to the study of the enzymatic profiles of yeast organisms with medical interest
    • Casal M, Linares MJ. 1983. Contribution to the study of the enzymatic profiles of yeast organisms with medical interest. Mycopathologia 81: 155-159. http://dx.doi.org/10.1007/BF00436820.
    • (1983) Mycopathologia , vol.81 , pp. 155-159
    • Casal, M.1    Linares, M.J.2
  • 137
    • 0018630615 scopus 로고
    • Cytochemical and biochemical identification of lysosomes in Cryptococcus neoformans
    • Mason DL, Wilson CL. 1979. Cytochemical and biochemical identification of lysosomes in Cryptococcus neoformans. Mycopathologia 68: 183-190. http://dx.doi.org/10.1007/BF00578528.
    • (1979) Mycopathologia , vol.68 , pp. 183-190
    • Mason, D.L.1    Wilson, C.L.2
  • 138
    • 0034768441 scopus 로고    scopus 로고
    • Cas1p is a membrane protein necessary for the O-acetylation of the Cryptococcus neoformans capsular polysaccharide
    • Janbon G, Himmelreich U, Moyrand F, Improvisi L, Dromer F. 2001. Cas1p is a membrane protein necessary for the O-acetylation of the Cryptococcus neoformans capsular polysaccharide. Mol Microbiol 42:453-467. http://dx.doi.org/10.1046/j.1365-2958.2001.02651.x.
    • (2001) Mol Microbiol , vol.42 , pp. 453-467
    • Janbon, G.1    Himmelreich, U.2    Moyrand, F.3    Improvisi, L.4    Dromer, F.5
  • 139
    • 34249736906 scopus 로고    scopus 로고
    • Chitosan, the deacetylated form of chitin, is necessary for cell wall integrity in Cryptococcus neoformans
    • Baker LG, Specht CA, Donlin MJ, Lodge JK. 2007. Chitosan, the deacetylated form of chitin, is necessary for cell wall integrity in Cryptococcus neoformans. Eukaryot Cell 6:855-867. http://dx.doi.org/10.1128/EC.00399-06.
    • (2007) Eukaryot Cell , vol.6 , pp. 855-867
    • Baker, L.G.1    Specht, C.A.2    Donlin, M.J.3    Lodge, J.K.4
  • 140
    • 27744569817 scopus 로고    scopus 로고
    • A chitin synthase and its regulator protein are critical for chitosan production and growth of the fungal pathogen Cryptococcus neoformans
    • Banks IR, Specht CA, Donlin MJ, Gerik KJ, Levitz SM, Lodge JK. 2005. A chitin synthase and its regulator protein are critical for chitosan production and growth of the fungal pathogen Cryptococcus neoformans. Eukaryot Cell 4:1902-1912. http://dx.doi.org/10.1128/EC.4.11.1902-1912.2005.
    • (2005) Eukaryot Cell , vol.4 , pp. 1902-1912
    • Banks, I.R.1    Specht, C.A.2    Donlin, M.J.3    Gerik, K.J.4    Levitz, S.M.5    Lodge, J.K.6
  • 141
    • 72449162169 scopus 로고    scopus 로고
    • Chitinases are essential for sexual development but not vegetative growth in Cryptococcus neoformans
    • Baker LG, Specht CA, Lodge JK. 2009. Chitinases are essential for sexual development but not vegetative growth in Cryptococcus neoformans. Eukaryot Cell 8:1692-1705. http://dx.doi.org/10.1128/EC.00227-09.
    • (2009) Eukaryot Cell , vol.8 , pp. 1692-1705
    • Baker, L.G.1    Specht, C.A.2    Lodge, J.K.3
  • 142
    • 0018931602 scopus 로고
    • Creatinine metabolism in Cryptococcus neoformans and Cryptococcus bacillisporus
    • Polacheck I, Kwon-Chung KJ. 1980. Creatinine metabolism in Cryptococcus neoformans and Cryptococcus bacillisporus. J Bacteriol 142:15-20.
    • (1980) J Bacteriol , vol.142 , pp. 15-20
    • Polacheck, I.1    Kwon-Chung, K.J.2
  • 143
    • 0035008701 scopus 로고    scopus 로고
    • Identification and characterization of the Cryptococcus neoformans phosphomannose isomerase-encoding gene, MAN1, and its impact on pathogenicity
    • Wills EA, Roberts IS, Del Poeta M, Rivera J, Casadevall A, Cox GM, Perfect JR. 2001. Identification and characterization of the Cryptococcus neoformans phosphomannose isomerase-encoding gene, MAN1, and its impact on pathogenicity. Mol Microbiol 40:610-620. http://dx.doi.org/10.1046/j.1365-2958.2001.02401.x.
    • (2001) Mol Microbiol , vol.40 , pp. 610-620
    • Wills, E.A.1    Roberts, I.S.2    Del Poeta, M.3    Rivera, J.4    Casadevall, A.5    Cox, G.M.6    Perfect, J.R.7
  • 144
    • 34249744432 scopus 로고    scopus 로고
    • The pathogenic fungus Cryptococcus neoformans expresses two functional GDP-mannose transporters with distinct expression patterns and roles in capsule synthesis
    • Cottrell TR, Griffith CL, Liu H, Nenninger AA, Doering TL. 2007. The pathogenic fungus Cryptococcus neoformans expresses two functional GDP-mannose transporters with distinct expression patterns and roles in capsule synthesis. Eukaryot Cell 6:776-785. http://dx.doi.org/10.1128/EC.00015-07.
    • (2007) Eukaryot Cell , vol.6 , pp. 776-785
    • Cottrell, T.R.1    Griffith, C.L.2    Liu, H.3    Nenninger, A.A.4    Doering, T.L.5
  • 145
    • 0041322579 scopus 로고    scopus 로고
    • Induction of T helper type 1 responses by a polysaccharide deacetylase from Cryptococcus neoformans
    • Biondo C, Beninati C, Bombaci M, Messina L, Mancuso G, Midiri A, Galbo R, Teti G. 2003. Induction of T helper type 1 responses by a polysaccharide deacetylase from Cryptococcus neoformans. Infect Immun 71:5412-5417. http://dx.doi.org/10.1128/IAI.71.9.5412-5417.2003.
    • (2003) Infect Immun , vol.71 , pp. 5412-5417
    • Biondo, C.1    Beninati, C.2    Bombaci, M.3    Messina, L.4    Mancuso, G.5    Midiri, A.6    Galbo, R.7    Teti, G.8
  • 146
    • 0035166540 scopus 로고    scopus 로고
    • Multiple virulence factors of Cryptococcus neoformans are dependent on VPH1
    • Erickson T, Liu L, Gueyikian A, Zhu XD, Gibbons J, Williamson PR. 2001. Multiple virulence factors of Cryptococcus neoformans are dependent on VPH1. Mol Microbiol 42:1121-1131. http://dx.doi.org/10.1046/j.1365-2958.2001.02712.x.
    • (2001) Mol Microbiol , vol.42 , pp. 1121-1131
    • Erickson, T.1    Liu, L.2    Gueyikian, A.3    Zhu, X.D.4    Gibbons, J.5    Williamson, P.R.6
  • 147
    • 0035834048 scopus 로고    scopus 로고
    • Functional cloning and characterization of a UDP-glucuronic acid decarboxylase: The pathogenic fungus Cryptococcus neoformans elucidates UDP-xylose synthesis
    • Bar-Peled M, Griffith CL, Doering TL. 2001. Functional cloning and characterization of a UDP-glucuronic acid decarboxylase: the pathogenic fungus Cryptococcus neoformans elucidates UDP-xylose synthesis. Proc Natl Acad Sci U S A 98:12003-12008. http://dx.doi.org/10.1073/pnas.211229198.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 12003-12008
    • Bar-Peled, M.1    Griffith, C.L.2    Doering, T.L.3
  • 148
    • 33646558235 scopus 로고    scopus 로고
    • The molecular basis for the immunogenicity of Cryptococcus neoformans mannoproteins
    • Levitz SM, Specht CA. 2006. The molecular basis for the immunogenicity of Cryptococcus neoformans mannoproteins. FEMS Yeast Res 6:513-524. http://dx.doi.org/10.1111/j.1567-1364.2006.00071.x.
    • (2006) FEMS Yeast Res , vol.6 , pp. 513-524
    • Levitz, S.M.1    Specht, C.A.2
  • 149
    • 0027478614 scopus 로고
    • Mannosyl transfer in Cryptococcus neoformans
    • White CW, Jacobson ES. 1993. Mannosyl transfer in Cryptococcus neoformans. Can J Microbiol 39:129-133. http://dx.doi.org/10.1139/m93-019.
    • (1993) Can J Microbiol , vol.39 , pp. 129-133
    • White, C.W.1    Jacobson, E.S.2
  • 150
    • 84907126632 scopus 로고
    • Electron cytochemical studies of Cryptococcus neoformans grown on uric acid and related sources of nitrogen
    • Fiskin AM, Zalles MC, Garrison RG. 1990. Electron cytochemical studies of Cryptococcus neoformans grown on uric acid and related sources of nitrogen. J Med Vet Mycol 28:197-207. http://dx.doi.org/10.1080/02681219080000261.
    • (1990) J Med Vet Mycol , vol.28 , pp. 197-207
    • Fiskin, A.M.1    Zalles, M.C.2    Garrison, R.G.3
  • 151
  • 152
    • 34249034938 scopus 로고    scopus 로고
    • Extracellular glycosylphosphatidylinositol-anchored mannoproteins and proteases of Cryptococcus neoformans
    • Eigenheer RA, Jin Lee Y, Blumwald E, Phinney BS, Gelli A. 2007. Extracellular glycosylphosphatidylinositol-anchored mannoproteins and proteases of Cryptococcus neoformans. FEMS Yeast Res 7:499-510. http://dx.doi.org/10.1111/j.1567-1364.2006.00198.x.
    • (2007) FEMS Yeast Res , vol.7 , pp. 499-510
    • Eigenheer, R.A.1    Jin Lee, Y.2    Blumwald, E.3    Phinney, B.S.4    Gelli, A.5
  • 153
    • 70350397502 scopus 로고    scopus 로고
    • Cryptococcus neoformans site-2 protease is required for virulence and survival in the presence of azole drugs
    • Bien CM, Chang YC, Nes WD, Kwon-Chung KJ, Espenshade PJ. 2009. Cryptococcus neoformans site-2 protease is required for virulence and survival in the presence of azole drugs. Mol Microbiol 74:672-690. http://dx.doi.org/10.1111/j.1365-2958.2009.06895.x.
    • (2009) Mol Microbiol , vol.74 , pp. 672-690
    • Bien, C.M.1    Chang, Y.C.2    Nes, W.D.3    Kwon-Chung, K.J.4    Espenshade, P.J.5
  • 154
    • 85004704150 scopus 로고
    • Distribution of the methylcitric acid cycle and beta-oxidation pathway for propionate catabolism in fungi
    • Miyakoshi S, Uchiyama H, Someya T, Satoh T, Tabuchi T. 1987. Distribution of the methylcitric acid cycle and beta-oxidation pathway for propionate catabolism in fungi. Agric Biol Chem 51:2381-2387. http://dx.doi.org/10.1271/bbb1961.51.2381.
    • (1987) Agric Biol Chem , vol.51 , pp. 2381-2387
    • Miyakoshi, S.1    Uchiyama, H.2    Someya, T.3    Satoh, T.4    Tabuchi, T.5
  • 155
    • 0027441959 scopus 로고
    • Effects of itraconazole on cytochrome P-450-dependent sterol 14 alpha-demethylation and reduction of 3-ketosteroids in Cryptococcus neoformans
    • Vanden Bossche H, Marichal P, Le Jeune L, Coene MC, Gorrens J, Cools W. 1993. Effects of itraconazole on cytochrome P-450-dependent sterol 14 alpha-demethylation and reduction of 3-ketosteroids in Cryptococcus neoformans. Antimicrob Agents Chemother 37:2101-2105. http://dx.doi.org/10.1128/AAC.37.10.2101.
    • (1993) Antimicrob Agents Chemother , vol.37 , pp. 2101-2105
    • Vanden Bossche, H.1    Marichal, P.2    Le Jeune, L.3    Coene, M.C.4    Gorrens, J.5    Cools, W.6
  • 156
    • 0030587543 scopus 로고    scopus 로고
    • Slow-binding inhibition of 6-phosphogluconate dehydrogenase by zinc ion
    • Niehaus WG, Richardson SB, Wolz RL. 1996. Slow-binding inhibition of 6-phosphogluconate dehydrogenase by zinc ion. Arch Biochem Biophys 333:333-337. http://dx.doi.org/10.1006/abbi.1996.0399.
    • (1996) Arch Biochem Biophys , vol.333 , pp. 333-337
    • Niehaus, W.G.1    Richardson, S.B.2    Wolz, R.L.3
  • 157
    • 0029593454 scopus 로고
    • Polyethylene sulfonate: A tight-binding inhibitor of 6-phosphogluconate dehydrogenase of Cryptococcus neoformans
    • Niehaus WG, White RH, Richardson SB, Bourne A, Ray WK. 1995. Polyethylene sulfonate: a tight-binding inhibitor of 6-phosphogluconate dehydrogenase of Cryptococcus neoformans. Arch Biochem Biophys 324: 325-330. http://dx.doi.org/10.1006/abbi.1995.0045.
    • (1995) Arch Biochem Biophys , vol.324 , pp. 325-330
    • Niehaus, W.G.1    White, R.H.2    Richardson, S.B.3    Bourne, A.4    Ray, W.K.5
  • 158
    • 84873148651 scopus 로고    scopus 로고
    • Crystal structures of acetate kinases from the eukaryotic pathogens Entamoeba histolytica and Cryptococcus neoformans
    • Thaker TM, Tanabe M, Fowler ML, Preininger AM, Ingram-Smith C, Smith KS, Iverson TM. 2013. Crystal structures of acetate kinases from the eukaryotic pathogens Entamoeba histolytica and Cryptococcus neoformans. J Struct Biol 181:185-189. http://dx.doi.org/10.1016/j.jsb.2012.11.001.
    • (2013) J Struct Biol , vol.181 , pp. 185-189
    • Thaker, T.M.1    Tanabe, M.2    Fowler, M.L.3    Preininger, A.M.4    Ingram-Smith, C.5    Smith, K.S.6    Iverson, T.M.7
  • 159
    • 33645054564 scopus 로고    scopus 로고
    • Posttranslational, translational, and transcriptional responses to nitric oxide stress in Cryptococcus neoformans: Implications for virulence
    • Missall TA, Pusateri ME, Donlin MJ, Chambers KT, Corbett JA, Lodge JK. 2006. Posttranslational, translational, and transcriptional responses to nitric oxide stress in Cryptococcus neoformans: implications for virulence. Eukaryot Cell 5:518-529. http://dx.doi.org/10.1128/EC.5.3.518-529.2006.
    • (2006) Eukaryot Cell , vol.5 , pp. 518-529
    • Missall, T.A.1    Pusateri, M.E.2    Donlin, M.J.3    Chambers, K.T.4    Corbett, J.A.5    Lodge, J.K.6
  • 161
    • 0141669024 scopus 로고    scopus 로고
    • Role of alternative oxidase gene in pathogenesis of Cryptococcus neoformans
    • Akhter S, McDade HC, Gorlach JM, Heinrich G, Cox GM, Perfect JR. 2003. Role of alternative oxidase gene in pathogenesis of Cryptococcus neoformans. Infect Immun 71:5794-5802. http://dx.doi.org/10.1128/IAI.71.10.5794-5802.2003.
    • (2003) Infect Immun , vol.71 , pp. 5794-5802
    • Akhter, S.1    McDade, H.C.2    Gorlach, J.M.3    Heinrich, G.4    Cox, G.M.5    Perfect, J.R.6
  • 162
    • 27844610829 scopus 로고    scopus 로고
    • Carbonic anhydrase and CO2 sensing during Cryptococcus neoformans growth, differentiation, and virulence
    • Bahn YS, Cox GM, Perfect JR, Heitman J. 2005. Carbonic anhydrase and CO2 sensing during Cryptococcus neoformans growth, differentiation, and virulence. Curr Biol 15:2013-2020. http://dx.doi.org/10.1016/j.cub.2005.09.047.
    • (2005) Curr Biol , vol.15 , pp. 2013-2020
    • Bahn, Y.S.1    Cox, G.M.2    Perfect, J.R.3    Heitman, J.4
  • 164
    • 80055111927 scopus 로고    scopus 로고
    • The casein kinase I protein Cck1 regulates multiple signaling pathways and is essential for cell integrity and fungal virulence in Cryptococcus neoformans
    • Wang YN, Liu TB, Patel S, Jiang LH, Xue CY. 2011. The casein kinase I protein Cck1 regulates multiple signaling pathways and is essential for cell integrity and fungal virulence in Cryptococcus neoformans. Eukaryot Cell 10:1455-1464. http://dx.doi.org/10.1128/EC.05207-11.
    • (2011) Eukaryot Cell , vol.10 , pp. 1455-1464
    • Wang, Y.N.1    Liu, T.B.2    Patel, S.3    Jiang, L.H.4    Xue, C.Y.5
  • 165
    • 10444242473 scopus 로고    scopus 로고
    • Cytochrome c peroxidase contributes to the antioxidant defense of Cryptococcus neoformans
    • Giles SS, Perfect JR, Cox GM. 2005. Cytochrome c peroxidase contributes to the antioxidant defense of Cryptococcus neoformans. Fungal Genet Biol 42:20-29. http://dx.doi.org/10.1016/j.fgb.2004.09.003.
    • (2005) Fungal Genet Biol , vol.42 , pp. 20-29
    • Giles, S.S.1    Perfect, J.R.2    Cox, G.M.3
  • 166
  • 167
    • 34247113199 scopus 로고    scopus 로고
    • Dolichol-linked oligosaccharide selection by the oligosaccharyltransferase in protist and fungal organisms
    • Kelleher DJ, Banerjee S, Cura AJ, Samuelson J, Gilmore R. 2007. Dolichol-linked oligosaccharide selection by the oligosaccharyltransferase in protist and fungal organisms. J Cell Biol 177:29-37. http://dx.doi.org/10.1083/jcb.200611079.
    • (2007) J Cell Biol , vol.177 , pp. 29-37
    • Kelleher, D.J.1    Banerjee, S.2    Cura, A.J.3    Samuelson, J.4    Gilmore, R.5
  • 168
    • 77955370227 scopus 로고    scopus 로고
    • Ferrochelatase is a conserved downstream target of the blue light-sensing white collar complex in fungi
    • Idnurm A, Heitman J. 2010. Ferrochelatase is a conserved downstream target of the blue light-sensing white collar complex in fungi. Microbiology 156:2393-2407. http://dx.doi.org/10.1099/mic.0.039222-0.
    • (2010) Microbiology , vol.156 , pp. 2393-2407
    • Idnurm, A.1    Heitman, J.2
  • 169
    • 75649103549 scopus 로고    scopus 로고
    • A putative P-type ATPase, Apt1, is involved in stress tolerance and virulence in Cryptococcus neoformans
    • Hu GG, Kronstad JW. 2010. A putative P-type ATPase, Apt1, is involved in stress tolerance and virulence in Cryptococcus neoformans. Eukaryot Cell 9:74-83. http://dx.doi.org/10.1128/EC.00289-09.
    • (2010) Eukaryot Cell , vol.9 , pp. 74-83
    • Hu, G.G.1    Kronstad, J.W.2
  • 171
    • 0028132922 scopus 로고
    • Purification and characterization of glucose-6-phosphate dehydrogenase from Cryptococcus neoformans identification as “nothing dehydrogenase.”
    • Niehaus WG, Mallett TC. 1994. Purification and characterization of glucose-6-phosphate dehydrogenase from Cryptococcus neoformans identification as “nothing dehydrogenase.” Arch Biochem Biophys 313: 304-309.
    • (1994) Arch Biochem Biophys , vol.313 , pp. 304-309
    • Niehaus, W.G.1    Mallett, T.C.2
  • 172
    • 0022529113 scopus 로고
    • Differentiation of Cryptococcus neoformans serotypes by isoenzyme electrophoresis
    • Safrin RE, Lancaster LA, Davis CE, Braude AI. 1986. Differentiation of Cryptococcus neoformans serotypes by isoenzyme electrophoresis. Am J Clin Pathol 86:204-208.
    • (1986) Am J Clin Pathol , vol.86 , pp. 204-208
    • Safrin, R.E.1    Lancaster, L.A.2    Davis, C.E.3    Braude, A.I.4
  • 173
    • 23844498015 scopus 로고    scopus 로고
    • Two glutathione peroxidases in the fungal pathogen Cryptococcus neoformans are expressed in the presence of specific substrates
    • Missall TA, Cherry-Harris JF, Lodge JK. 2005. Two glutathione peroxidases in the fungal pathogen Cryptococcus neoformans are expressed in the presence of specific substrates. Microbiology 151:2573-2581. http://dx.doi.org/10.1099/mic.0.28132-0.
    • (2005) Microbiology , vol.151 , pp. 2573-2581
    • Missall, T.A.1    Cherry-Harris, J.F.2    Lodge, J.K.3
  • 174
    • 53449087032 scopus 로고    scopus 로고
    • Threonine biosynthetic genes are essential in Cryptococcus neoformans
    • Kingsbury JM, McCusker JH. 2008. Threonine biosynthetic genes are essential in Cryptococcus neoformans. Microbiology 154:2767-2775. http://dx.doi.org/10.1099/mic.0.2008/019729-0.
    • (2008) Microbiology , vol.154 , pp. 2767-2775
    • Kingsbury, J.M.1    McCusker, J.H.2
  • 176
    • 34547894212 scopus 로고    scopus 로고
    • Identification and characterization of CPS1 as a hyaluronic acid synthase contributing to the pathogenesis of Cryptococcus neoformans infection
    • Jong A, Wu CH, Chen HM, Luo F, Kwon-Chung KJ, Chang YC, LaMunyon CW, Plaas A, Huang SH. 2007. Identification and characterization of CPS1 as a hyaluronic acid synthase contributing to the pathogenesis of Cryptococcus neoformans infection. Eukaryot Cell 6:1486-1496. http://dx.doi.org/10.1128/EC.00120-07.
    • (2007) Eukaryot Cell , vol.6 , pp. 1486-1496
    • Jong, A.1    Wu, C.H.2    Chen, H.M.3    Luo, F.4    Kwon-Chung, K.J.5    Chang, Y.C.6    Lamunyon, C.W.7    Plaas, A.8    Huang, S.H.9
  • 177
    • 0028284095 scopus 로고
    • Cloning, sequence analysis and expression of the gene encoding imidazole glycerol phosphate dehydratase in Cryptococcus neoformans
    • Parker AR, Moore TD, Edman JC, Schwab JM, Davisson VJ. 1994. Cloning, sequence analysis and expression of the gene encoding imidazole glycerol phosphate dehydratase in Cryptococcus neoformans. Gene 145:135-138. http://dx.doi.org/10.1016/0378-1119(94)90336-0.
    • (1994) Gene , vol.145 , pp. 135-138
    • Parker, A.R.1    Moore, T.D.2    Edman, J.C.3    Schwab, J.M.4    Davisson, V.J.5
  • 178
    • 77956518464 scopus 로고    scopus 로고
    • Crystallization and preliminary X-ray analysis of mycophenolic acidresistant and mycophenolic acid-sensitive forms of IMP dehydrogenase from the human fungal pathogen Cryptococcus
    • Morrow CA, Stamp A, Valkov E, Kobe B, Fraser JA. 2010. Crystallization and preliminary X-ray analysis of mycophenolic acidresistant and mycophenolic acid-sensitive forms of IMP dehydrogenase from the human fungal pathogen Cryptococcus. Acta Crystallogr Sect F Struct Biol Cryst Commun 66:1104-1107. http://dx.doi.org/10.1107/S1744309110031659.
    • (2010) Acta Crystallogr Sect F Struct Biol Cryst Commun , vol.66 , pp. 1104-1107
    • Morrow, C.A.1    Stamp, A.2    Valkov, E.3    Kobe, B.4    Fraser, J.A.5
  • 179
    • 2442701773 scopus 로고    scopus 로고
    • The sphingolipid pathway regulates Pkc1 through the formation of diacylglycerol in Cryptococcus neoformans
    • Heung LJ, Luberto C, Plowden A, Hannun YA, Del Poeta M. 2004. The sphingolipid pathway regulates Pkc1 through the formation of diacylglycerol in Cryptococcus neoformans. J Biol Chem 279:21144-21153. http://dx.doi.org/10.1074/jbc.M312995200.
    • (2004) J Biol Chem , vol.279 , pp. 21144-21153
    • Heung, L.J.1    Luberto, C.2    Plowden, A.3    Hannun, Y.A.4    Del Poeta, M.5
  • 180
    • 80052309751 scopus 로고    scopus 로고
    • Unique evolution of the UPR pathway with a novel bZIP transcription factor, Hxl1, for controlling pathogenicity of Cryptococcus neoformans
    • Cheon SA, Jung KW, Chen YL, Heitman J, Bahn YS, Kang HA. 2011. Unique evolution of the UPR pathway with a novel bZIP transcription factor, Hxl1, for controlling pathogenicity of Cryptococcus neoformans. PLoS Pathog 7:e1002177. http://dx.doi.org/10.1371/journal.ppat.1002177.
    • (2011) Plos Pathog , vol.7
    • Cheon, S.A.1    Jung, K.W.2    Chen, Y.L.3    Heitman, J.4    Bahn, Y.S.5    Kang, H.A.6
  • 181
    • 0036786526 scopus 로고    scopus 로고
    • Relationship of the glyoxylate pathway to the pathogenesis of Cryptococcus neoformans
    • Rude TH, Toffaletti DL, Cox GM, Perfect JR. 2002. Relationship of the glyoxylate pathway to the pathogenesis of Cryptococcus neoformans. Infect Immun 70:5684-5694. http://dx.doi.org/10.1128/IAI.70.10.5684-5694.2002.
    • (2002) Infect Immun , vol.70 , pp. 5684-5694
    • Rude, T.H.1    Toffaletti, D.L.2    Cox, G.M.3    Perfect, J.R.4
  • 182
    • 0029082980 scopus 로고
    • Purification and characterization of malate dehydrogenase from Cryptococcus neoformans
    • Mahmoud YA, el Souod SM, Niehaus WG. 1995. Purification and characterization of malate dehydrogenase from Cryptococcus neoformans. Arch Biochem Biophys 322:69-75. http://dx.doi.org/10.1006/abbi.1995.1437.
    • (1995) Arch Biochem Biophys , vol.322 , pp. 69-75
    • Mahmoud, Y.A.1    El Souod, S.M.2    Niehaus, W.G.3
  • 183
    • 0029788982 scopus 로고    scopus 로고
    • Identification of a Cryptococcus neoformans gene that directs expression of the cryptic Saccharomyces cerevisiae mannitol dehydrogenase gene
    • Perfect JR, Rude TH, Wong B, Flynn T, Chaturvedi V, Niehaus W. 1996. Identification of a Cryptococcus neoformans gene that directs expression of the cryptic Saccharomyces cerevisiae mannitol dehydrogenase gene. J Bacteriol 178:5257-5262.
    • (1996) J Bacteriol , vol.178 , pp. 5257-5262
    • Perfect, J.R.1    Rude, T.H.2    Wong, B.3    Flynn, T.4    Chaturvedi, V.5    Niehaus, W.6
  • 184
    • 0033754075 scopus 로고    scopus 로고
    • Mannitol-1-phosphate dehydrogenase from Cryptococcus neoformans is a zinc-containing long-chain alcohol/polyol dehydrogenase
    • Suvarna K, Bartiss A, Wong B. 2000. Mannitol-1-phosphate dehydrogenase from Cryptococcus neoformans is a zinc-containing long-chain alcohol/polyol dehydrogenase. Microbiology 146:2705-2713. http://dx.doi.org/10.1099/00221287-146-10-2705.
    • (2000) Microbiology , vol.146 , pp. 2705-2713
    • Suvarna, K.1    Bartiss, A.2    Wong, B.3
  • 185
    • 33847229448 scopus 로고    scopus 로고
    • Role of protein O-mannosyltransferase Pmt4 in the morphogenesis and virulence of Cryptococcus neoformans
    • Olson GM, Fox DS, Wang P, Alspaugh JA, Buchanan KL. 2007. Role of protein O-mannosyltransferase Pmt4 in the morphogenesis and virulence of Cryptococcus neoformans. Eukaryot Cell 6:222-234. http://dx.doi.org/10.1128/EC.00182-06.
    • (2007) Eukaryot Cell , vol.6 , pp. 222-234
    • Olson, G.M.1    Fox, D.S.2    Wang, P.3    Alspaugh, J.A.4    Buchanan, K.L.5
  • 186
    • 29144439796 scopus 로고    scopus 로고
    • Pde1 phosphodiesterase modulates cyclic AMP levels through a protein kinase A-mediated negative feedback loop in Cryptococcus neoformans
    • Hicks JK, Bahn YS, Heitman J. 2005. Pde1 phosphodiesterase modulates cyclic AMP levels through a protein kinase A-mediated negative feedback loop in Cryptococcus neoformans. Eukaryot Cell 4:1971-1981. http://dx.doi.org/10.1128/EC.4.12.1971-1981.2005.
    • (2005) Eukaryot Cell , vol.4 , pp. 1971-1981
    • Hicks, J.K.1    Bahn, Y.S.2    Heitman, J.3
  • 187
    • 80053400607 scopus 로고    scopus 로고
    • Structures of Cryptococcus neoformans protein farnesyltransferase reveal strategies for developing inhibitors that target fungal pathogens
    • Hast MA, Nichols CB, Armstrong SM, Kelly SM, Hellinga HW, Alspaugh JA, Beese LS. 2011. Structures of Cryptococcus neoformans protein farnesyltransferase reveal strategies for developing inhibitors that target fungal pathogens. J Biol Chem 286:35149-35162. http://dx.doi.org/10.1074/jbc.M111.250506.
    • (2011) J Biol Chem , vol.286 , pp. 35149-35162
    • Hast, M.A.1    Nichols, C.B.2    Armstrong, S.M.3    Kelly, S.M.4    Hellinga, H.W.5    Alspaugh, J.A.6    Beese, L.S.7
  • 189
    • 61649084414 scopus 로고    scopus 로고
    • The evolutionary study of small RNA-directed gene silencing pathways by investigating RNase III enzymes
    • Jin LH, Kryukov K, Suzuki Y, Imanishi T, Ikeo K, Gojobori T. 2009. The evolutionary study of small RNA-directed gene silencing pathways by investigating RNase III enzymes. Gene 435:1-8. http://dx.doi.org/10.1016/j.gene.2008.12.022.
    • (2009) Gene , vol.435 , pp. 1-8
    • Jin, L.H.1    Kryukov, K.2    Suzuki, Y.3    Imanishi, T.4    Ikeo, K.5    Gojobori, T.6
  • 190
    • 2942635960 scopus 로고    scopus 로고
    • Novel chimeric spermidine synthase-saccharopine dehydrogenase gene (SPE3-LYS9) in the human pathogen Cryptococcus neoformans
    • Kingsbury JM, Yang Z, Ganous TM, Cox GM, McCusker JH. 2004. Novel chimeric spermidine synthase-saccharopine dehydrogenase gene (SPE3-LYS9) in the human pathogen Cryptococcus neoformans. Eukaryot Cell 3:752-763. http://dx.doi.org/10.1128/EC.3.3.752-763.2004.
    • (2004) Eukaryot Cell , vol.3 , pp. 752-763
    • Kingsbury, J.M.1    Yang, Z.2    Ganous, T.M.3    Cox, G.M.4    McCusker, J.H.5
  • 192
    • 33748294197 scopus 로고    scopus 로고
    • Design, synthesis, and antifungal activities in vitro of novel tetrahydroisoquinoline compounds based on the structure of lanosterol 14alpha-demethylase (CYP51) of fungi
    • Zhu J, Lu J, Zhou Y, Li Y, Cheng J, Zheng C. 2006. Design, synthesis, and antifungal activities in vitro of novel tetrahydroisoquinoline compounds based on the structure of lanosterol 14alpha-demethylase (CYP51) of fungi. Bioorg Med Chem Lett 16:5285-5289. http://dx.doi.org/10.1016/j.bmcl.2006.08.001.
    • (2006) Bioorg Med Chem Lett , vol.16 , pp. 5285-5289
    • Zhu, J.1    Lu, J.2    Zhou, Y.3    Li, Y.4    Cheng, J.5    Zheng, C.6
  • 193
    • 58049098654 scopus 로고    scopus 로고
    • Sterol 24-C-methyltransferase: An enzymatic target for the disruption of ergosterol biosynthesis and homeostasis in Cryptococcus neoformans
    • Nes WD, Zhou W, Ganapathy K, Liu J, Vatsyayan R, Chamala S, Hernandez K, Miranda M. 2009. Sterol 24-C-methyltransferase: an enzymatic target for the disruption of ergosterol biosynthesis and homeostasis in Cryptococcus neoformans. Arch Biochem Biophys 481:210-218. http://dx.doi.org/10.1016/j.abb.2008.11.003.
    • (2009) Arch Biochem Biophys , vol.481 , pp. 210-218
    • Nes, W.D.1    Zhou, W.2    Ganapathy, K.3    Liu, J.4    Vatsyayan, R.5    Chamala, S.6    Hernandez, K.7    Miranda, M.8
  • 194
    • 1542511805 scopus 로고    scopus 로고
    • Thiol peroxidase is critical for virulence and resistance to nitric oxide and peroxide in the fungal pathogen, Cryptococcus neoformans
    • Missall TA, Pusateri ME, Lodge JK. 2004. Thiol peroxidase is critical for virulence and resistance to nitric oxide and peroxide in the fungal pathogen, Cryptococcus neoformans. Mol Microbiol 51:1447-1458. http://dx.doi.org/10.1111/j.1365-2958.2004.03921.x.
    • (2004) Mol Microbiol , vol.51 , pp. 1447-1458
    • Missall, T.A.1    Pusateri, M.E.2    Lodge, J.K.3
  • 195
    • 13844316982 scopus 로고    scopus 로고
    • Thioredoxin reductase is essential for viability in the fungal pathogen Cryptococcus neoformans
    • Missall TA, Lodge JK. 2005. Thioredoxin reductase is essential for viability in the fungal pathogen Cryptococcus neoformans. Eukaryot Cell 4:487-489. http://dx.doi.org/10.1128/EC.4.2.487-489.2005.
    • (2005) Eukaryot Cell , vol.4 , pp. 487-489
    • Missall, T.A.1    Lodge, J.K.2
  • 196
    • 0028569078 scopus 로고
    • Cloning, expression and characterization of thymidylate synthase from Cryptococcus neoformans
    • Livi LL, Edman U, Schneider GP, Greene PJ, Santi DV. 1994. Cloning, expression and characterization of thymidylate synthase from Cryptococcus neoformans. Gene 150:221-226. http://dx.doi.org/10.1016/0378-1119(94)90430-8.
    • (1994) Gene , vol.150 , pp. 221-226
    • Livi, L.L.1    Edman, U.2    Schneider, G.P.3    Greene, P.J.4    Santi, D.V.5
  • 197
    • 33749254466 scopus 로고    scopus 로고
    • Characterization and regulation of the trehalose synthesis pathway and its importance in the pathogenicity of Cryptococcus neoformans
    • Petzold EW, Himmelreich U, Mylonakis E, Rude T, Toffaletti D, Cox GM, Miller JL, Perfect JR. 2006. Characterization and regulation of the trehalose synthesis pathway and its importance in the pathogenicity of Cryptococcus neoformans. Infect Immun 74:5877-5887. http://dx.doi.org/10.1128/IAI.00624-06.
    • (2006) Infect Immun , vol.74 , pp. 5877-5887
    • Petzold, E.W.1    Himmelreich, U.2    Mylonakis, E.3    Rude, T.4    Toffaletti, D.5    Cox, G.M.6    Miller, J.L.7    Perfect, J.R.8
  • 199
    • 84907126644 scopus 로고
    • Cryptococcal UDP-glucose dehydrogenase: Enzymic control of capsular biosynthesis
    • Jacobson ES. 1987. Cryptococcal UDP-glucose dehydrogenase: enzymic control of capsular biosynthesis. J Med Vet Mycol 25:131-135. http://dx.doi.org/10.1080/02681218780000201.
    • (1987) J Med Vet Mycol , vol.25 , pp. 131-135
    • Jacobson, E.S.1
  • 200
    • 73649098812 scopus 로고    scopus 로고
    • A novel xylosylphosphotransferase activity discovered in Cryptococcus neoformans
    • Reilly MC, Levery SB, Castle SA, Klutts JS, Doering TL. 2009. A novel xylosylphosphotransferase activity discovered in Cryptococcus neoformans. J Biol Chem 284:36118-36127. http://dx.doi.org/10.1074/jbc.M109.056226.
    • (2009) J Biol Chem , vol.284 , pp. 36118-36127
    • Reilly, M.C.1    Levery, S.B.2    Castle, S.A.3    Klutts, J.S.4    Doering, T.L.5
  • 201
    • 0015638741 scopus 로고
    • 5-Fluorocytosine resistance in Cryptococcus neoformans
    • Block ER, Jennings AE, Bennett JE. 1973. 5-Fluorocytosine resistance in Cryptococcus neoformans. Antimicrob Agents Chemother 3:649-656. http://dx.doi.org/10.1128/AAC.3.6.649.
    • (1973) Antimicrob Agents Chemother , vol.3 , pp. 649-656
    • Block, E.R.1    Jennings, A.E.2    Bennett, J.E.3
  • 202
    • 33846014710 scopus 로고    scopus 로고
    • Combination of amphotericin B with flucytosine is active in vitro against flucytosine-resistant isolates of Cryptococcus neoformans
    • Schwarz P, Janbon G, Dromer F, Lortholary O, Dannaoui E. 2007. Combination of amphotericin B with flucytosine is active in vitro against flucytosine-resistant isolates of Cryptococcus neoformans. Antimicrob Agents Chemother 51:383-385. http://dx.doi.org/10.1128/AAC.00446-06.
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 383-385
    • Schwarz, P.1    Janbon, G.2    Dromer, F.3    Lortholary, O.4    Dannaoui, E.5


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