Phospholipase C of Cryptococcus neoformans regulates homeostasis and virulence by providing inositol trisphosphate as a substrate for Arg1 kinase

Infection and Immunity

Volumn 81, Issue 4, 2013, Pages 1245-1255

  Lev, Sophie ^a   Desmarini, Desmarini ^a   Li, Cecilia ^a   Chayakulkeeree, Methee ^b   Traven, Ana ^c   Sorrell, Tania C ^a,d   Djordjevic, Julianne T ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b MAHIDOL UNIVERSITY   (Thailand)

^c MONASH UNIVERSITY   (Australia)

^d UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CALCINEURIN; INOSITOL TRISPHOSPHATE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PHOSPHOLIPASE C;

ARTICLE; CRYPTOCOCCUS NEOFORMANS; FUNGAL STRAIN; GALLERIA MELLONELLA; HEAT TOLERANCE; HOMEOSTASIS; HYDROLYSIS; MUTANT; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; VIRULENCE;

ANIMALS; ARGINASE; CRYPTOCOCCUS NEOFORMANS; GENE DELETION; INOSITOL 1,4,5-TRISPHOSPHATE; LEPIDOPTERA; METABOLIC NETWORKS AND PATHWAYS; MODELS, ANIMAL; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; PROTEIN KINASES; SIGNAL TRANSDUCTION; SURVIVAL ANALYSIS; TYPE C PHOSPHOLIPASES; VIRULENCE; VIRULENCE FACTORS;

EID: 84875544623     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.01421-12     Document Type: Article

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