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Volumn 47, Issue 6, 2003, Pages 1681-1694

Characterization of Cu,Zn superoxide dismutase (SOD1) gene knock-out mutant of Cryptococcus neoformans var. gattii: Role in biology and virulence

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; COPPER ZINC SUPEROXIDE DISMUTASE; LACCASE; MENADIONE; PHOSPHOLIPASE; UREASE; VIRULENCE FACTOR;

EID: 0345268706     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.2003.03393.x     Document Type: Article
Times cited : (79)

References (58)
  • 1
    • 0030668723 scopus 로고    scopus 로고
    • Cryptococcus neoformans mating and virulence are regulated by the G-protein α subunit GPA1 and cAMP
    • Alspaugh, J.A., Perfect, J.R., and Heitman, J. (1997) Cryptococcus neoformans mating and virulence are regulated by the G-protein α subunit GPA1 and cAMP. Genes Dev 11: 3206-3217.
    • (1997) Genes Dev , vol.11 , pp. 3206-3217
    • Alspaugh, J.A.1    Perfect, J.R.2    Heitman, J.3
  • 4
    • 0004274349 scopus 로고    scopus 로고
    • Washington, DC: American Society for Microbiology Press
    • Casadevall, A., and Perfect, J.R. (1998) Cryptococcus neoformans. Washington, DC: American Society for Microbiology Press, pp.1-531.
    • (1998) Cryptococcus Neoformans , pp. 1-531
    • Casadevall, A.1    Perfect, J.R.2
  • 5
    • 0034610855 scopus 로고    scopus 로고
    • Cryptococcus neoformans STE12alpha regulates virulence but is not essential for mating
    • Chang, Y.C., Wickes, B.L., Miller, G.F., Penoyer, L.A., and Kwon-Chung, K.J. (2000) Cryptococcus neoformans STE12alpha regulates virulence but is not essential for mating. J Exp Med 191: 871-882.
    • (2000) J Exp Med , vol.191 , pp. 871-882
    • Chang, Y.C.1    Wickes, B.L.2    Miller, G.F.3    Penoyer, L.A.4    Kwon-Chung, K.J.5
  • 6
    • 0035795587 scopus 로고    scopus 로고
    • Molecular cloning, phylogenetic analysis and three-dimensional modeling of Cu,Zn superoxide dismutase (CnSOD1) from three varieties of Cryptococcus neoformans
    • Chaturvedi, S., Hamilton, A.J., Hobby, P., Zhu, G., Lowry, C.V., and Chaturvedi, V. (2001) Molecular cloning, phylogenetic analysis and three-dimensional modeling of Cu,Zn superoxide dismutase (CnSOD1) from three varieties of Cryptococcus neoformans. Gene 268: 41-51.
    • (2001) Gene , vol.268 , pp. 41-51
    • Chaturvedi, S.1    Hamilton, A.J.2    Hobby, P.3    Zhu, G.4    Lowry, C.V.5    Chaturvedi, V.6
  • 7
    • 0029967748 scopus 로고    scopus 로고
    • Oxidative killing of Cryptococcus neoformans by human neutrophils. Evidence that fungal mannitol protects by scavenging reactive oxygen intermediates
    • Chaturvedi, V., Wong, B., and Newman, S.L. (1996) Oxidative killing of Cryptococcus neoformans by human neutrophils. Evidence that fungal mannitol protects by scavenging reactive oxygen intermediates. J Immunol 156: 3836-3840.
    • (1996) J Immunol , vol.156 , pp. 3836-3840
    • Chaturvedi, V.1    Wong, B.2    Newman, S.L.3
  • 8
    • 0036719924 scopus 로고    scopus 로고
    • Molecular genetic analyses of mating pheromones reveals intervariety mating/hybridization in Cryptococcus neoformans
    • Chaturvedi, V., Fan, J., Stein, B., Behr, M.J., Samsonoff, W.A., Wickes, B.L., and Chaturvedi, S. (2002) Molecular genetic analyses of mating pheromones reveals intervariety mating/hybridization in Cryptococcus neoformans. Infect Immun 70: 5225-5235.
    • (2002) Infect Immun , vol.70 , pp. 5225-5235
    • Chaturvedi, V.1    Fan, J.2    Stein, B.3    Behr, M.J.4    Samsonoff, W.A.5    Wickes, B.L.6    Chaturvedi, S.7
  • 9
    • 0031019618 scopus 로고    scopus 로고
    • Phospholipase activity in Cryptococcus neoformans: A new virulence factor?
    • Chen, S.C., Muller, A.M., Zhou, J.Z., Wright, L.C., and Sorrell, T.C. (1997) Phospholipase activity in Cryptococcus neoformans: a new virulence factor? J Infect Dis 175: 414-420.
    • (1997) J Infect Dis , vol.175 , pp. 414-420
    • Chen, S.C.1    Muller, A.M.2    Zhou, J.Z.3    Wright, L.C.4    Sorrell, T.C.5
  • 10
    • 0034457941 scopus 로고    scopus 로고
    • Epidemiology and host- and variety-dependent characteristics of infection due to Cryptococcus neoformans in Australia and New Zealand
    • Australasian Cryptococcal Study Group
    • Chen, S., Sorrell, T., Nimmo, G., Speed, B., Currie, B., Ellis, D., et al. (2000) Epidemiology and host- and variety-dependent characteristics of infection due to Cryptococcus neoformans in Australia and New Zealand. Australasian Cryptococcal Study Group. Clin Infect Dis 31: 499-508.
    • (2000) Clin Infect Dis , vol.31 , pp. 499-508
    • Chen, S.1    Sorrell, T.2    Nimmo, G.3    Speed, B.4    Currie, B.5    Ellis, D.6
  • 11
    • 0002414340 scopus 로고
    • Comparison of virulence among serotypes of Cryptococcus neoformans in a murine inhalation model
    • Washington, DC: American Society for Microbiology Press, Abstract B-328
    • Church, D., and Washburn, R. (1992) Comparison of virulence among serotypes of Cryptococcus neoformans in a murine inhalation model. In Abstracts of the General Meeting. Washington, DC: American Society for Microbiology Press, Abstract B-328, p. 80.
    • (1992) Abstracts of the General Meeting , pp. 80
    • Church, D.1    Washburn, R.2
  • 13
    • 0035179848 scopus 로고    scopus 로고
    • Extracellular phospholipase activity is a virulence factor for Cryptococcus neoformans
    • Cox, G.M., McDade, H.C., Chen, S.C., Tucker, S.C., Gottfredsson, M., Wright, L.C., et al. (2001) Extracellular phospholipase activity is a virulence factor for Cryptococcus neoformans. Mol Microbiol 39: 166-175.
    • (2001) Mol Microbiol , vol.39 , pp. 166-175
    • Cox, G.M.1    McDade, H.C.2    Chen, S.C.3    Tucker, S.C.4    Gottfredsson, M.5    Wright, L.C.6
  • 14
    • 0033977390 scopus 로고    scopus 로고
    • Comparison of the roles of calcineurin in physiology and virulence in serotype D and serotype A strains of Cryptococcus neoformans
    • Cruz, M.C., Sia, R.A., Olson, M., Cox, G.M., and Heitman, J. (2000) Comparison of the roles of calcineurin in physiology and virulence in serotype D and serotype A strains of Cryptococcus neoformans. Infect Immun 68: 982-985.
    • (2000) Infect Immun , vol.68 , pp. 982-985
    • Cruz, M.C.1    Sia, R.A.2    Olson, M.3    Cox, G.M.4    Heitman, J.5
  • 15
    • 0034001825 scopus 로고    scopus 로고
    • Gene disruption by biolistic transformation in serotype D strains of Cryptococcus neoformans
    • Davidson, R.C., Cruz, M.C., Sia, R.A.L., Allen, B., Alspaugh, J.A., and Heitman, J. (1999) Gene disruption by biolistic transformation in serotype D strains of Cryptococcus neoformans. Fungal Genet Biol 29: 38-48.
    • (1999) Fungal Genet Biol , vol.29 , pp. 38-48
    • Davidson, R.C.1    Cruz, M.C.2    Sia, R.A.L.3    Allen, B.4    Alspaugh, J.A.5    Heitman, J.6
  • 16
    • 0029060903 scopus 로고
    • Effects of two varieties of Cryptococcus neoformans cells and culture filtrate antigens on neutrophil locomotion
    • Dong, Z.M., and Murphy, J.W. (1995) Effects of two varieties of Cryptococcus neoformans cells and culture filtrate antigens on neutrophil locomotion. Infect Immun 63: 2632-2644.
    • (1995) Infect Immun , vol.63 , pp. 2632-2644
    • Dong, Z.M.1    Murphy, J.W.2
  • 17
    • 0025079475 scopus 로고
    • Isolation of the URA5 gene from Cryptococcus neoformans var. neoformans and its use as a selectable marker for transformation
    • Edman, J.C., and Kwon-Chung, K.J. (1990) Isolation of the URA5 gene from Cryptococcus neoformans var. neoformans and its use as a selectable marker for transformation. Mol Cell Biol 10: 4538-4544.
    • (1990) Mol Cell Biol , vol.10 , pp. 4538-4544
    • Edman, J.C.1    Kwon-Chung, K.J.2
  • 19
    • 0035166540 scopus 로고    scopus 로고
    • Multiple virulence factors of Cryptococcus neoformans are dependent on VPH1
    • Erickson, T., Liu, L., Gueyikian, A., Zhu, X., Gibbons, J., and Williamson, P.R. (2001) Multiple virulence factors of Cryptococcus neoformans are dependent on VPH1. Mol Microbiol 42: 1121-1131.
    • (2001) Mol Microbiol , vol.42 , pp. 1121-1131
    • Erickson, T.1    Liu, L.2    Gueyikian, A.3    Zhu, X.4    Gibbons, J.5    Williamson, P.R.6
  • 20
    • 0027740356 scopus 로고
    • Cryptococcus neoformans tropical northern Australia: Predominantly variant gattii with good outcomes
    • Fisher, D., Burrow, J., Lo, D., and Currie, B. (1993) Cryptococcus neoformans tropical northern Australia: predominantly variant gattii with good outcomes. Aust NZ J Med 23: 678-682.
    • (1993) Aust NZ J Med , vol.23 , pp. 678-682
    • Fisher, D.1    Burrow, J.2    Lo, D.3    Currie, B.4
  • 21
    • 0015497506 scopus 로고
    • The purification and properties of superoxide dismutase from Saccharomyces cerevisiae
    • Goscin, S.A., and Fridovich, I. (1972) The purification and properties of superoxide dismutase from Saccharomyces cerevisiae. Biochim Biophys Acta 289: 276-283.
    • (1972) Biochim Biophys Acta , vol.289 , pp. 276-283
    • Goscin, S.A.1    Fridovich, I.2
  • 22
    • 0025938799 scopus 로고
    • Null mutants of Saccharomyces cerevisiae Cu,Zn superoxide dismutase: Characterization of spontaneous mutation rates
    • Gralla, E., and Valentine, J.S. (1991) Null mutants of Saccharomyces cerevisiae Cu,Zn superoxide dismutase: characterization of spontaneous mutation rates. J Bacteriol 173: 5918-5920.
    • (1991) J Bacteriol , vol.173 , pp. 5918-5920
    • Gralla, E.1    Valentine, J.S.2
  • 23
    • 0025994140 scopus 로고
    • Guide to yeast genetics and molecular biology
    • San Diego, CA: Academic Press
    • Guthrie, C., and Fink, G.R. (1991) Guide to Yeast Genetics and Molecular Biology. In Methods in Enzymology. San Diego, CA: Academic Press.
    • (1991) Methods in Enzymology
    • Guthrie, C.1    Fink, G.R.2
  • 24
    • 0031018901 scopus 로고    scopus 로고
    • Biochemical comparison of the Cu,Zn superoxide dismutases of Cryptococcus neoformans var. neoformans and Cryptococcus neoformans var. gatti
    • Hamilton, A.J., and Holdom, M.D. (1997) Biochemical comparison of the Cu,Zn superoxide dismutases of Cryptococcus neoformans var. neoformans and Cryptococcus neoformans var. gatti. Infect Immun 65: 488-494.
    • (1997) Infect Immun , vol.65 , pp. 488-494
    • Hamilton, A.J.1    Holdom, M.D.2
  • 25
    • 0029945919 scopus 로고    scopus 로고
    • Expression of the Cu,Zn superoxide dismutase of Aspergillus fumigatus as determined by immunochemistry and immunoelectron microscopy
    • Hamilton, A.J., Holdom, M.D., and Jeavons, L. (1996) Expression of the Cu,Zn superoxide dismutase of Aspergillus fumigatus as determined by immunochemistry and immunoelectron microscopy. FEMS Immunol Med Microbiol 14: 95-102.
    • (1996) FEMS Immunol Med Microbiol , vol.14 , pp. 95-102
    • Hamilton, A.J.1    Holdom, M.D.2    Jeavons, L.3
  • 26
    • 0032940248 scopus 로고    scopus 로고
    • Copper- and zinc-containing superoxide dismutase and its gene from Candida albicans
    • Hwang, C., Rhie, S.G., Kim, S.T., Kim, Y.R., Huh, W.K., Baek, Y.U., and Kang, S.O. (1999) Copper- and zinc-containing superoxide dismutase and its gene from Candida albicans. Biochim Biophys Acta 1427: 245-255.
    • (1999) Biochim Biophys Acta , vol.1427 , pp. 245-255
    • Hwang, C.1    Rhie, S.G.2    Kim, S.T.3    Kim, Y.R.4    Huh, W.K.5    Baek, Y.U.6    Kang, S.O.7
  • 27
    • 0032439653 scopus 로고    scopus 로고
    • Oxidative stress responses of the yeast Saccharomyces cerevisiae
    • Jamieson, D.J. (1998) Oxidative stress responses of the yeast Saccharomyces cerevisiae. Yeast 14: 1511-1527.
    • (1998) Yeast , vol.14 , pp. 1511-1527
    • Jamieson, D.J.1
  • 28
    • 0030465238 scopus 로고    scopus 로고
    • Superoxide accelerates DNA damage by elevating free-iron levels
    • Keyer, K., and Imlay, J.A. (1996) Superoxide accelerates DNA damage by elevating free-iron levels. Proc Natl Acad Sci USA 93: 13635-13640.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 13635-13640
    • Keyer, K.1    Imlay, J.A.2
  • 30
    • 0020008452 scopus 로고
    • Taxonomic studies on Filobasidiella species and their anamorphs
    • Kwon-Chung, K.J., Bennett, J.E., and Rhodes, J.C. (1982) Taxonomic studies on Filobasidiella species and their anamorphs. Antonie van Leeuwenhoek 48: 25-38.
    • (1982) Antonie van Leeuwenhoek , vol.48 , pp. 25-38
    • Kwon-Chung, K.J.1    Bennett, J.E.2    Rhodes, J.C.3
  • 31
    • 84907124004 scopus 로고
    • Selection of ura5 and ura3 mutants from the two varieties of Cryptococcus neoformans on 5-fluoroorotic acid medium
    • Kwon-Chung, K.J., Varma, A., Edman, J.C., and Bennett, J.E. (1992) Selection of ura5 and ura3 mutants from the two varieties of Cryptococcus neoformans on 5-fluoroorotic acid medium. J Med Vet Mycol 30: 61-69.
    • (1992) J Med Vet Mycol , vol.30 , pp. 61-69
    • Kwon-Chung, K.J.1    Varma, A.2    Edman, J.C.3    Bennett, J.E.4
  • 32
    • 0035941352 scopus 로고    scopus 로고
    • Candida albicans expresses an unusual cytoplasmic manganese-containing superoxide dismutase (SOD3 gene product) upon the entry and during the stationary phase
    • Lamarre, C., LeMay, J.D., Deslauriers, N., and Bourbonnais, Y. (2001) Candida albicans expresses an unusual cytoplasmic manganese-containing superoxide dismutase (SOD3 gene product) upon the entry and during the stationary phase. J Biol Chem 276: 43784-43791.
    • (2001) J Biol Chem , vol.276 , pp. 43784-43791
    • Lamarre, C.1    LeMay, J.D.2    Deslauriers, N.3    Bourbonnais, Y.4
  • 35
    • 0028053746 scopus 로고
    • Targeted gene replacement demonstrates that myristoyl-CoA: Protein N-myristoyltransferase is essential for viability of Cryptococcus neoformans
    • Lodge, J.K., Jackson-Machelski, E., Toffaletti, D.L., Perfect, J.R., and Gordon, J.I. (1994) Targeted gene replacement demonstrates that myristoyl-CoA: protein N-myristoyltransferase is essential for viability of Cryptococcus neoformans. Proc Natl Acad Sci USA 91: 12008-12012.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 12008-12012
    • Lodge, J.K.1    Jackson-Machelski, E.2    Toffaletti, D.L.3    Perfect, J.R.4    Gordon, J.I.5
  • 36
    • 15844429977 scopus 로고    scopus 로고
    • Superoxide dismutase activity is essential for stationary phase survival in Saccharomyces cerevisiae
    • Longo, V.D., Gralla, E.B., and Valentine, J.S. (1996) Superoxide dismutase activity is essential for stationary phase survival in Saccharomyces cerevisiae. J Biol Chem 271: 12275-12280.
    • (1996) J Biol Chem , vol.271 , pp. 12275-12280
    • Longo, V.D.1    Gralla, E.B.2    Valentine, J.S.3
  • 39
    • 0031029702 scopus 로고    scopus 로고
    • Role of oxidants in microbial pathophysiology
    • Miller, R.A., and Britigan, B.E. (1997) Role of oxidants in microbial pathophysiology. Clin Microbiol Rev 10: 1-18.
    • (1997) Clin Microbiol Rev , vol.10 , pp. 1-18
    • Miller, R.A.1    Britigan, B.E.2
  • 40
    • 0015501087 scopus 로고
    • The purification and properties of superoxide dismutase from Neurospora crassa
    • Misra, H.P., and Fridovich, I. (1972) The purification and properties of superoxide dismutase from Neurospora crassa. J Biol Chem 247: 3410-3414.
    • (1972) J Biol Chem , vol.247 , pp. 3410-3414
    • Misra, H.P.1    Fridovich, I.2
  • 41
    • 0036944062 scopus 로고    scopus 로고
    • Characterization of Cu,Zn-superoxide dismutase-deficient mutant of fission yeast Schizosaccharomyces pombe
    • Mutoh, N.C., Nakagawa, W., and Yamada, K. (2002) Characterization of Cu,Zn-superoxide dismutase-deficient mutant of fission yeast Schizosaccharomyces pombe. Curr Genet 41: 82-88.
    • (2002) Curr Genet , vol.41 , pp. 82-88
    • Mutoh, N.C.1    Nakagawa, W.2    Yamada, K.3
  • 42
    • 0031008864 scopus 로고    scopus 로고
    • Calcineurin is required for virulence of Cryptococcus neoformans
    • Odom, A., Muir, S., Lim, E., Toffaletti, D.L., Perfect, J., and Heitman, J. (1997) Calcineurin is required for virulence of Cryptococcus neoformans. EMBO J 16: 2576-2589.
    • (1997) EMBO J , vol.16 , pp. 2576-2589
    • Odom, A.1    Muir, S.2    Lim, E.3    Toffaletti, D.L.4    Perfect, J.5    Heitman, J.6
  • 43
    • 0034931506 scopus 로고    scopus 로고
    • Spatial and temporal sequence of capsule construction in Cryptococcus neoformans
    • Pierini, L.M., and Doering, T.L. (2001) Spatial and temporal sequence of capsule construction in Cryptococcus neoformans. Mol Microbiol 41: 105-115.
    • (2001) Mol Microbiol , vol.41 , pp. 105-115
    • Pierini, L.M.1    Doering, T.L.2
  • 44
    • 0028824707 scopus 로고
    • Redox signaling and the control of cell growth and death
    • Powis, G., Briehl, M., and Oblong, J. (1995) Redox signaling and the control of cell growth and death. Pharmacol Ther 68: 149-173.
    • (1995) Pharmacol Ther , vol.68 , pp. 149-173
    • Powis, G.1    Briehl, M.2    Oblong, J.3
  • 45
    • 0033013295 scopus 로고    scopus 로고
    • Generation of a superoxide dismutase (SOD)-deficient mutant of Campylobacter coli. evidence for the significance of SOD in Campylobacter survival and colonization
    • Purdy, D., Cawthraw, S., Dickinson, J.H., Newell, D.G., and Park, S.F. (1999) Generation of a superoxide dismutase (SOD)-deficient mutant of Campylobacter coli. evidence for the significance of SOD in Campylobacter survival and colonization. Appl Environ Microbiol 65: 2540-2546.
    • (1999) Appl Environ Microbiol , vol.65 , pp. 2540-2546
    • Purdy, D.1    Cawthraw, S.2    Dickinson, J.H.3    Newell, D.G.4    Park, S.F.5
  • 46
    • 0024284213 scopus 로고
    • Iron storage in Saccharomyces cerevisiae
    • Raguzzi, F., Lesuisse, E., and Crichton, R.R. (1988) Iron storage in Saccharomyces cerevisiae. FEBS Lett 231: 253-258.
    • (1988) FEBS Lett , vol.231 , pp. 253-258
    • Raguzzi, F.1    Lesuisse, E.2    Crichton, R.R.3
  • 47
  • 48
    • 0018511757 scopus 로고
    • Further simplification of Guizotia abyssinica seed medium for identification of Cryptococcus neoformans and Cryptococcus bacillispora
    • Salkin, I.F. (1979) Further simplification of Guizotia abyssinica seed medium for identification of Cryptococcus neoformans and Cryptococcus bacillispora. Can J Microbiol 25: 1116-1118.
    • (1979) Can J Microbiol , vol.25 , pp. 1116-1118
    • Salkin, I.F.1
  • 49
    • 0000163138 scopus 로고
    • Analysis of genomic DNA by southern hybridization
    • Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press
    • Sambrook, J., Fritsch, E.F., and Maniatis, T. (1989) Analysis of genomic DNA by Southern Hybridization. In Molecular Cloning: A Laboratory Manual, Vol. 1, 2nd edn. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 9.31-9.45.
    • (1989) Molecular Cloning: A Laboratory Manual, 2nd Edn. , vol.1 , pp. 931-945
    • Sambrook, J.1    Fritsch, E.F.2    Maniatis, T.3
  • 50
    • 0012609432 scopus 로고    scopus 로고
    • Colorimetric assay of alditols in complex biological samples
    • Sanchez, J. (1998) Colorimetric assay of alditols in complex biological samples. J Agric Food Chem 46: 157-160.
    • (1998) J Agric Food Chem , vol.46 , pp. 157-160
    • Sanchez, J.1
  • 51
    • 0035001195 scopus 로고    scopus 로고
    • Superoxide dismutase-deficient mutants of Helicobacter pylori are hypersensitive to oxidative stress and defective in host colonization
    • Seyler, R.W., Jr, Olson, J.W., and Maier, R.J. (2001) Superoxide dismutase-deficient mutants of Helicobacter pylori are hypersensitive to oxidative stress and defective in host colonization. Infect Immun 69: 4034-4040.
    • (2001) Infect Immun , vol.69 , pp. 4034-4040
    • Seyler R.W., Jr.1    Olson, J.W.2    Maier, R.J.3
  • 52
    • 0035039544 scopus 로고    scopus 로고
    • Cryptococcus neoformans variety gattii
    • Sorrell, T.C. (2001) Cryptococcus neoformans variety gattii. Med Mycol 39: 155-168.
    • (2001) Med Mycol , vol.39 , pp. 155-168
    • Sorrell, T.C.1
  • 53
    • 0029072394 scopus 로고
    • Clinical and host differences between infections with two varieties of Cryptococcus neoformans
    • Speed, B., and Dunt, D. (1995) Clinical and host differences between infections with two varieties of Cryptococcus neoformans. Clin Infect Dis 21: 28-34.
    • (1995) Clin Infect Dis , vol.21 , pp. 28-34
    • Speed, B.1    Dunt, D.2
  • 54
    • 0027467293 scopus 로고
    • Gene transfer in Cryptococcus neoformans by use of biolistic delivery of DNA
    • Toffaletti, D., Rude, T.H., Johnston, S.A., Durack, D.T., and Perfect, J.R. (1993) Gene transfer in Cryptococcus neoformans by use of biolistic delivery of DNA. J Bacteriol 175: 1405-1411.
    • (1993) J Bacteriol , vol.175 , pp. 1405-1411
    • Toffaletti, D.1    Rude, T.H.2    Johnston, S.A.3    Durack, D.T.4    Perfect, J.R.5
  • 55
    • 0029759409 scopus 로고    scopus 로고
    • Superoxide dismutase protects calcineurin from inactivation
    • Wang, X., Culaotta, V.C., and Kliee, C. (1996) Superoxide dismutase protects calcineurin from inactivation. Nature 383: 434-437.
    • (1996) Nature , vol.383 , pp. 434-437
    • Wang, X.1    Culaotta, V.C.2    Kliee, C.3
  • 56
    • 0029951165 scopus 로고    scopus 로고
    • Dimorphism and haploid fruiting in Cryptococcus neoformans: Association with the α-mating type
    • Wickes, B.L., Mayorga, M.E., Edman, U., and Edman, J.C. (1996) Dimorphism and haploid fruiting in Cryptococcus neoformans: Association with the α-mating type. Proc Natl Acad Sci USA 93: 7327-7331.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 7327-7331
    • Wickes, B.L.1    Mayorga, M.E.2    Edman, U.3    Edman, J.C.4
  • 57
    • 0032585880 scopus 로고    scopus 로고
    • The STE12 alpha homolog is required for haploid filamentation but largely dispensable for mating and virulence in Cryptococcus neoformans
    • Yue, C.L., Cavallo, M., Alspaugh, J.A., Wang, P., Cox, G.M., Perfect, J.R., and Heitman, J. (1999) The STE12 alpha homolog is required for haploid filamentation but largely dispensable for mating and virulence in Cryptococcus neoformans. Genetics 153: 1601-1615.
    • (1999) Genetics , vol.153 , pp. 1601-1615
    • Yue, C.L.1    Cavallo, M.2    Alspaugh, J.A.3    Wang, P.4    Cox, G.M.5    Perfect, J.R.6    Heitman, J.7
  • 58
    • 0033580279 scopus 로고    scopus 로고
    • The Cryptococcus neoformans uses 'mammalian' enhancer sites in the regulation of the virulence gene CNLAC1
    • Zhang, S., Varma, A., and Williamson, P.R. (1999) The Cryptococcus neoformans uses 'mammalian' enhancer sites in the regulation of the virulence gene CNLAC1. Gene 227: 231-240.
    • (1999) Gene , vol.227 , pp. 231-240
    • Zhang, S.1    Varma, A.2    Williamson, P.R.3


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