Cryptococcus neoformans Site-2 protease is required for virulence and survival in the presence of azole drugs

Molecular Microbiology

Volumn 74, Issue 3, 2009, Pages 672-690

  Bien, Clara M ^a   Chang, Yun C ^b   Nes, W David ^c   Kwon Chung, Kyung J ^b   Espenshade, Peter J ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c TEXAS TECH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

25 THIALANOSTEROL; ANTIFUNGAL AGENT; FLUCONAZOLE; ITRACONAZOLE; KETOCONAZOLE; METALLOPROTEINASE; PROTIN SRE1; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; STP1 ENZYME; UNCLASSIFIED DRUG; VORICONAZOLE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CRYPTOCOCCUS NEOFORMANS; ENZYME ACTIVITY; FEMALE; FUNGAL CELL; FUNGAL STRAIN; FUNGAL VIRULENCE; GENE EXPRESSION; GENETIC TRANSCRIPTION; HYPOXIA; MOUSE; MYCOSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; STEROL SYNTHESIS; SURVIVAL RATE; TRANSCRIPTION INITIATION;

ANIMALS; ANTIFUNGAL AGENTS; AZOLES; CRYPTOCOCCOSIS; CRYPTOCOCCUS NEOFORMANS; ENDOPEPTIDASES; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; GENOME, FUNGAL; HUMANS; ITRACONAZOLE; MICE; MICE, INBRED BALB C; MUTATION; PROMOTER REGIONS, GENETIC; PROTEIN KINASES; SCHIZOSACCHAROMYCES POMBE PROTEINS; SIGNAL TRANSDUCTION; TRANSCRIPTIONAL ACTIVATION; UBIQUITIN-PROTEIN LIGASES; VIRULENCE;

FILOBASIDIELLA NEOFORMANS; MAMMALIA;

EID: 70350397502     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/j.1365-2958.2009.06895.x     Document Type: Article

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