Invasion of the central nervous system by Cryptococcus neoformans requires a secreted fungal metalloprotease

mBio

Volumn 5, Issue 3, 2014, Pages

  Vu, Kiem ^a   Tham, Rick ^b   Uhrig, John P ^a   Thompson III, George R ^a   Na Pombejra, Sarisa ^a   Jamklang, Mantana ^a   Bautos, Jennifer M ^c   Gelli, Angie ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SAN DIEGO STATE UNIVERSITY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYALURONIC ACID; METALLOPROTEINASE; METALLOPROTEINASE 1; UNCLASSIFIED DRUG; FUNGAL PROTEIN; VIRULENCE FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOLOGICAL MODEL; BLOOD BRAIN BARRIER; CELL MIGRATION; CENTRAL NERVOUS SYSTEM INFECTION; CONTROLLED STUDY; CRYPTOCOCCAL MENINGITIS; CRYPTOCOCCUS NEOFORMANS; ENDOTHELIUM; ENZYME ACTIVITY; ENZYME RELEASE; FUNGAL GENE; FUNGAL STRAIN; FUNGAL VIRULENCE; GENE TARGETING; HOST PATHOGEN INTERACTION; MENINGOENCEPHALITIS; MOUSE; MPR1 GENE; NONHUMAN; PRIORITY JOURNAL; PROTEOMICS; SURVIVAL RATE; YEAST CELL; ANIMAL; BRAIN; CRYPTOCOCCOSIS; DISEASE MODEL; ENZYMOLOGY; EXTRACELLULAR SPACE; GENE EXPRESSION; GENETICS; METABOLISM; MICROBIOLOGY; PATHOGENICITY; PATHOLOGY; ULTRASTRUCTURE;

ANIMALS; BLOOD-BRAIN BARRIER; BRAIN; CRYPTOCOCCOSIS; CRYPTOCOCCUS NEOFORMANS; DISEASE MODELS, ANIMAL; ENDOTHELIUM; EXTRACELLULAR SPACE; FUNGAL PROTEINS; GENE EXPRESSION; MENINGOENCEPHALITIS; METALLOPROTEASES; MICE; VIRULENCE FACTORS;

EID: 84903978023     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.01101-14     Document Type: Article

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