The second capsule gene of Cryptococcus neoformans, CAP64, is essential for virulence

Infection and Immunity

Volumn 64, Issue 6, 1996, Pages 1977-1983

  Chang, Yun C ^a   Penoyer, Lisa A ^a   Kwon Chung, K J ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BACTERIAL VIRULENCE; CHROMOSOME ANALYSIS; CRYPTOCOCCUS NEOFORMANS; DATA BASE; DNA SEQUENCE; GENE DELETION; GENE EXPRESSION; GENE ISOLATION; GENE MUTATION; PATHOGENICITY; PRIORITY JOURNAL; YEAST;

EID: 0029886340     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.64.6.1977-1983.1996     Document Type: Article

References (28)

1. Bhattacharjee, A. K., J. E. Bennett, and C. P. Glaudemans. 1984. Capsular polysaccharides of Cryptococcus neoformans. Rev. Infect. Dis. 6:619-624.
2. Bhattachaijee, A. K., K. J. Kwon-Chung, and C. P. Glaudemans. 1979. On the structure of the capsular polysaccharide from Cryptococcus neoformans serotype C. II. Mol. Immunol. 16:531-532.
3. Bhattachaijee, A. K., K. J. Kwon-Chung, and C. P. Glaudemans. 1981. Capsular polysaccharides from a parent strain and from a possible mutant strain of Cryptococcus neoformans serotype A. Carbohydr. Res. 95:237-248.
4. Bhattacharjee, A. K., K. J. Kwon-Chung, and C. P. Glaudemans. 1992. The major capsular polysaccharide of Cryptococcus neoformans serotype B. Carbohydr. Res. 233:271-272.
5. Chang, Y. C., and K. J. Kwon-Chung. 1994. Complementation of a capsule-deficient mutation of Cryptococcus neoformans restores its virulence. Mol. Cell. Biol. 14:4912-4919.
6. Chang, Y. C., B. L. Wickes, and K. J. Kwon-Chung. 1995. Further analysis of the CAP59 locus of Cryptococcus neoformans: structure defined by forced expression and description of a new ribosomal protein-encoding gene. Gene 167:179-183.
7. Cherniak, R., E. Reiss, and S. H. Turner. 1982. A galactoxylomannan antigen of Cryptococcus neoformans serotypes A. Carbohydr. Res. 103:239-250.
8. Devereux, J., P. Haeberli, and O. Smithies. 1984. A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res. 12:387-395.
9. Driscoll, J. 1994. The role of the proteasome in cellular protein degradation. Histol. Histopathol. 9:197-202.
10. Edman, J. C., and K. J. Kwon-Chung. 1990. Isolation of the URA5 gene from Cryptococcus neoformans var. neoformans and its use as a selective marker for transformation. Mol. Cell. Biol. 10:4538-4544.
11. Feinberg, A. P., and B. Vogelstein. 1983. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 132:6-13.
12. Fromptling, R. A., H. K. Shadomy, and E. S. Jacobson. 1982. Decreased virulence in stable acapsular mutants of Cryptococcus neoformans. Mycopathologia 79:23-29.
13. Heinemeyer, W., J. A. Kleinschmidt, J. Saidowsky, C. Escher, and D. H. Wolf. 1991. Proteinase yscE, the yeast proteasome/multicatalytic-multifunctional proteinase: mutants unravel its function in stress induced proteolysis and uncover its necessity for cell survival. EMBO J. 10:555-562.
14. Jacobson, E. S., and W. R. Payne. 1982. UDP-glucuronate decarboxylase and synthesis of capsular polysaccharide in Cryptococcus neoformans. J. Bacteriol. 152:932-934.
15. Kwon-Chung, K. J. 1976. Morphogenesis of Filobasidiella neoformans, the sexual state of Cryptococcus neoformans. Mycologia 68:821-833.
16. Kwon-Chung, K. J., and J. E. Bennett. 1992. Medical mycology, p. 397-446. Lea & Febiger, Philadelphia.
17. Kwon-Chung, K. J., J. E. Bennett, and J. C. Rhodes. 1982. Taxonomic studies on Filobasidiella species and their anamorphs. Antonie Leeuwenhoek 48:25-38.
18. Kwon-Chung, K. J., J. C. Edman, and B. L. Wickes. 1992. Genetic association of mating types and virulence in Cryptococcus neoformans. Infect. Immun. 60:602-605.
19. Kwon-Chung, K. J., and J. C. Rhodes. 1986. Encapsulation and melanin formation as indicators of virulence in Cryptococcus neoformans. Infect. Immun. 51:218-223.
20. Kwon-Chung, K. J., A. Varma, J. C. Edman, and J. E. Bennett. 1992. Selection of ura5 and ura3 mutants from the two varieties of Cryptococcus neoformans on 5-fluoroorotic acid medium. J. Med. Vet. Mycol. 30:61-69.
21. Nishimura, C., T. Tamura, F. Tokunaga, K. Tanaka, and A. Ichihara. 1993. cDNA cloning of rat proteasome subunit RC7-I, a homologue of yeast PRE1 essential for chymotrypsin-like activity. FEBS Lett. 332:52-56.
22. Rivett, A. J. 1993. Proteasomes: multicatalytic proteinase complexes. Biochem. J. 291:1-10.
23. Still, C. N., and E. S. Jacobson. 1983. Recombinational mapping of capsule mutations in Cryptococcus neoformans. J. Bacteriol. 156:460-462.
24. Tanaka, K., T. Tamura, T. Yoshimura, and A. Ichihara. 1992. Proteasomes: protein and gene structures. New Biol. 4:173-187.
25. Turner, S. H., R. Cherniak, E. Reiss, and C. K. Kwon. 1992. Structural variability in the glucuronoxylomannan of Cryptococcus neoformans serotype A isolates determined by 13C NMR spectroscopy. Carbohydr. Res. 233:205-218.
26. Varma, A., J. C. Edman, and K. J. Kwon-Chung. 1992. Molecular and genetic analysis of VRAS transformants of Cryptococcus neoformans. Infect. Immun. 60:1101-1108.
27. White, C. W., R. Cherniak, and E. S. Jacobson. 1990. Side group addition by xylosyltransferase and glucuronyltransferase in biosynthesis of capsular polysaccharide in Cryptococcus neoformans. J. Med. Vet. Mycol. 28:289-301.
28. Zwickl, P., A. Grziwa, G. Puhler, B. Dahlmann, F. Lottspeich, and W. Baumeister. 1992. Primary structure of the Thermoplasma proteasome and its implications for the structure, function, and evolution of the multicatalytic proteinase. Biochemistry 31:964-972.