Melanin, melanin 'ghosts,' and melanin composition in Cryptococcus neoformans

Infection and Immunity

Volumn 64, Issue 7, 1996, Pages 2420-2424

  Wang, Yulin ^a   Aisen, Philip ^a   Casadevall, Arturo ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATECHOL; DOPAMINE; HYDROCHLORIC ACID; HYPOCHLORITE SODIUM; ISOTHIOCYANIC ACID DERIVATIVE; LEVODOPA; MELANIN; ZINC;

ARTICLE; BLEACHING; CONTROLLED STUDY; CRYPTOCOCCUS NEOFORMANS; ELECTRON SPIN RESONANCE; MELANOGENESIS; NONHUMAN; PRIORITY JOURNAL; TEMPERATURE DEPENDENCE;

EID: 0029883404     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.64.7.2420-2424.1996     Document Type: Article

References (23)

1. Blasi, E., R. Barluzzi, R. Mazzolla, B. Tancini, S. Saleppico, M. Puliti, L. Pitzurra, and F. Bistoni. 1995. Role of nitric oxide and melanogenesis in the accomplishment of anticryptococcal activity by the BV-2 microglial cell line. J. Neuroimmunol. 58:111-116.
2. Chedekel, M. R., A. B. Ahene, and L. Zeise. 1992. Melanin standard method: empirical formula 2. Pigment Cell Res. 5:240-246.
3. Currie, B. P., and A. Casadevall. 1994. Estimation of the prevalence of cryptococcal infection among patients infected with the human immunodeficiency virus in New York City. Clin. Infect. Dis. 19:1029-1033.
4. Dubois, M., K. A. Gilles, J. K. Hamilton, P. A. Rebers, and F. Smith. 1956. Colorimetric method for determination of sugars and related substances. Anal. Chem. 28:350-356.
5. Enochs, W. S., M. J. Nilges, and H. M. Swartz. 1993. A standardized test for the identification and characterization of melanins using electron paramagnetic (EPR) spectroscopy. Pigment Cell Res. 6:91-99.
6. Jacobson, E. S., and H. S. Emery. 1991. Temperature regulation of the cryptococcal phenoloxidase. J. Med. Vet. Mycol. 29:121-124.
7. Jacobson, E. S., N. D. Jenkins, and J. M. Todd. 1994. Relationship between superoxide dismutase and melanin in a pathogenic fungus. Infect. Immun. 62:4085-4086.
8. Jacobson, E. S., and S. B. Tinnell. 1993. Antioxidant function of fungal melanin. J. Bacteriol. 175:7102-7104.
9. Kwon-Chung, K. J., I. Polacheck, and T. J. Popkin. 1982. Melanin-lacking mutants of Cryptococcus neoformans and their virulence for mice. J. Bacteriol. 150:1414-1421.
10. Kwon-Chung, K. J., and J. Rhodes. 1986. Encapsulation and melanin formation as indicators of virulence in Cryptococcus neoformans. Infect. Immun. 51:218-223.
11. Lee, S. C., D. W. Dickson, and A. Casadevall. Pathology of cryptococcal meningoencephalitis: analysis of 27 patients with pathogeretic implications. Hum. Pathol., in press.
12. Moslen, M. T. 1994. Reactive oxygen species in normal physiology, cell injury and phagocytosis, p. 17-27. In D. Armstrong (ed.). Free radicals in diagnostic medicine. Plenum Press, New York.
13. Mukherjee, J., W. Cleare, and A. Casadevall. 1995. Monoclonal antibody mediated capsular reactions (Quellung) in Cryptococcus neoformans. J. Immunol. Methods 184:139-143.
14. Polacheck, I., V. J. Hearing, and K. J. Kwon-Chung. 1982. Biochemical studies of phenoloxidase and utilization of catecholamines in Cryptococcus neoformans. J. Bacteriol. 150:1212-1220.
15. Polacheck, I., Y. Platt, and J. Aronovitch. 1990. Catecholamines and virulence of Cryptococcus neoformans. Infect. Immun. 58:2919-2922.
16. Rhodes, J., I. Polacheck, and K. J. Kwon-Chung. 1982. Phenoloxidase activity and virulence in isogenic strains of Cryptococcus neoformans. Infect. Immun. 36:1175-1184.
17. Sealy, R. C., C. C. Felix, J. S. Hyde, and H. M. Swartz. 1980. Structure and reactivity of melanins: influence of free radicals and metal ions, p. 209-259. In Free radicals in biology. Academic Press, New York.
18. Wang, Y., P. Aisen, and A. Casadevall. 1995. Cryptococcus neoformans melanin and virulence: mechanism of action. Infect. Immun. 63:3131-3136.
19. Wang, Y., and A. Casadevall. 1994. Decreased susceptibility of melanized Cryptococcus neoformans to the fungicidal effects of ultraviolet light. Appl. Environ. Microbiol. 60:3864-3866.
20. Wang, Y., and A. Casadevall. 1994. Growth of Cryptococcus neoformans in presence of L-dopa decreases its susceptibility to amphotericin B. Antimicrob. Agents Chemother. 38:2648-2650.
21. Wang, Y., and A. Casadevall. 1994. Susceptibility of melanized and nonmelanized Cryptococcus neoformans to nitrogen- and oxygen-derived oxidants. Infect. Immun. 62:3004-3007.
22. Wheeler, M. H., and A. A. Bell. 1988. Melanins and their importance in pathogenic fungi. Curr. Top. Med. Mycol. 2:338-387.
23. Williamson, P. R. 1994. Biochemical and molecular characterization of the diphenol oxidase of Cryptococcus neoformans: identification as a laccase. J. Bacteriol. 176:656-664.