Sterol 24-C-methyltransferase: An enzymatic target for the disruption of ergosterol biosynthesis and homeostasis in Cryptococcus neoformans

Archives of Biochemistry and Biophysics

Volumn 481, Issue 2, 2009, Pages 210-218

  Nes, W David ^a   Zhou, Wenxu ^a   Ganapathy, Kulothungan ^a   Liu, JiaLin ^a   Vatsyayan, Rit ^a   Chamala, Swetha ^a   Hernandez, Keven ^a   Miranda, Mayra ^a  

^a TEXAS TECH UNIVERSITY   (United States)

Author keywords

Amphotericin B; Antifungal agent; Ergosterol; Ergosterol biosynthesis inhibitor; Itraconazole; Lanosterol; Membrane; Sterol methyl transferase

Indexed keywords

24 BETA AMINOLANOSTEROL; 25 AMINOLANOSTEROL; 25 AZALANOSTEROL; 25 EPIMINOLANOSTEROL; 25 THIA IODIDE LANOST 8 ENOL; 26 NOR 25 THIA LANOST 8 ENOL; 32 AMINO 24 DIHYDROLANOSTEROL; AMPHOTERICIN B; ERGOSTEROL; ITRACONAZOLE; LANOSTEROL; METHIONINE; METHYLTRANSFERASE; STEROL; STEROL 24 C METHYLTRANSFERASE; UNCLASSIFIED DRUG; ZYMOSTEROL;

ARTICLE; CONTROLLED STUDY; CRYPTOCOCCUS NEOFORMANS; ENZYME SPECIFICITY; FUNGUS GROWTH; GROWTH INHIBITION; HOMEOSTASIS; LIPOGENESIS; NONHUMAN; PRIORITY JOURNAL; STEROL ANALYSIS;

CHOLESTEROL; CHROMATOGRAPHY, GAS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRYPTOCOCCUS NEOFORMANS; ERGOSTEROL; FUNGAL PROTEINS; HOMEOSTASIS; KINETICS; LANOSTEROL; METHIONINE; METHYLTRANSFERASES; MICROSOMES; STEROLS;

FILOBASIDIELLA NEOFORMANS;

EID: 58049098654     PISSN: 00039861     EISSN: 10960384     Source Type: Journal    
DOI: 10.1016/j.abb.2008.11.003     Document Type: Article

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