-
1
-
-
8844255630
-
Free fatty acids in obesity and type 2 diabetes: Defining their role in the development of insulin resistance and β-cell dysfunction
-
Boden G, Shulman GI. Free fatty acids in obesity and type 2 diabetes: defining their role in the development of insulin resistance and β-cell dysfunction. J Clin Invest 2002;32(Suppl 3):14-23.
-
(2002)
J Clin Invest
, vol.32
, Issue.SUPPL. 3
, pp. 14-23
-
-
Boden, G.1
Shulman, G.I.2
-
2
-
-
29244444549
-
Nonalcoholic steatohepatitis and the metabolic syndrome
-
Neuschwander-Tetri B. Nonalcoholic steatohepatitis and the metabolic syndrome. Am J Med Sci 2005;330:326-335.
-
(2005)
Am J Med Sci
, vol.330
, pp. 326-335
-
-
Neuschwander-Tetri, B.1
-
3
-
-
33748150370
-
Pathophysiology of nonalcoholic steatohepatitis
-
McCullough AJ. Pathophysiology of nonalcoholic steatohepatitis. J Clin Gastroenterol 2006;40(Suppl 1):S17-S29.
-
(2006)
J Clin Gastroenterol
, vol.40
, Issue.SUPPL. 1
-
-
McCullough, A.J.1
-
4
-
-
0031947715
-
Steatohepatitis: A tale of two hits?
-
Day CP, James OF. Steatohepatitis: a tale of two hits? Gastroenterology 1998;114:842-845.
-
(1998)
Gastroenterology
, vol.114
, pp. 842-845
-
-
Day, C.P.1
James, O.F.2
-
5
-
-
28944443012
-
Interleukin-8
-
Remick DG. Interleukin-8. Crit Care Med 2005;33(12 Suppl):S466-S467.
-
(2005)
Crit Care Med
, vol.33
, Issue.12 SUPPL.
-
-
Remick, D.G.1
-
6
-
-
33748099699
-
Circulating levels of MCP-1 and IL-8 are elevated in human obese subjects and associated with obesity-related parameters
-
Kim CS, Park HS, Kawada T, Kim JH, Lim D, Hubbard NE, et al. Circulating levels of MCP-1 and IL-8 are elevated in human obese subjects and associated with obesity-related parameters. Int J Obes (Lond) 2006; 30:1347-1355.
-
(2006)
Int J Obes (Lond)
, vol.30
, pp. 1347-1355
-
-
Kim, C.S.1
Park, H.S.2
Kawada, T.3
Kim, J.H.4
Lim, D.5
Hubbard, N.E.6
-
7
-
-
0036548118
-
Comments. Inflammation in response to hepatocellular apoptosis
-
Jaeschke H, Mullen KD, Moradpour D. Comments. Inflammation in response to hepatocellular apoptosis. HEPATOLOGY 2002;35:964-965.
-
(2002)
HEPATOLOGY
, vol.35
, pp. 964-965
-
-
Jaeschke, H.1
Mullen, K.D.2
Moradpour, D.3
-
8
-
-
0027296643
-
Increased plasma interleukin-8 concentrations in alcoholic hepatitis
-
Hill DB, Marsano L, McClain CJ. Increased plasma interleukin-8 concentrations in alcoholic hepatitis. HEPATOLOGY 1993;18:576-580.
-
(1993)
HEPATOLOGY
, vol.18
, pp. 576-580
-
-
Hill, D.B.1
Marsano, L.2
McClain, C.J.3
-
9
-
-
0142151770
-
Inhibition of proteasome function leads to NF-κB-independent IL-8 expression in human hepatocytes
-
Joshi-Barve S, Barve SS, Butt W, Klein J, McClain CJ. Inhibition of proteasome function leads to NF-κB-independent IL-8 expression in human hepatocytes. HEPATOLOGY 2003;38:1178-1187.
-
(2003)
HEPATOLOGY
, vol.38
, pp. 1178-1187
-
-
Joshi-Barve, S.1
Barve, S.S.2
Butt, W.3
Klein, J.4
McClain, C.J.5
-
10
-
-
0025234842
-
Cytokine-induced gene expression of a neutrophil chemotactic factor/IL-8 in human hepatocytes
-
Thornton AJ, Strieter RM, Lindley I, Baggiolini M, Kunkel SL. Cytokine-induced gene expression of a neutrophil chemotactic factor/IL-8 in human hepatocytes. J Immunol 1990;144:2609-2613.
-
(1990)
J Immunol
, vol.144
, pp. 2609-2613
-
-
Thornton, A.J.1
Strieter, R.M.2
Lindley, I.3
Baggiolini, M.4
Kunkel, S.L.5
-
11
-
-
0042265627
-
Cytokines and NASH: A pilot study of the effects of lifestyle modification and vitamin E
-
Kugelmas M, Hill DB, Vivian B, Marsano L, McClain CJ. Cytokines and NASH: a pilot study of the effects of lifestyle modification and vitamin E. HEPATOLOGY 2003;38:413-419.
-
(2003)
HEPATOLOGY
, vol.38
, pp. 413-419
-
-
Kugelmas, M.1
Hill, D.B.2
Vivian, B.3
Marsano, L.4
McClain, C.J.5
-
12
-
-
25844508967
-
Levels of serum hyaluronic acid, TNF-α and IL-8 in patients with nonalcoholic steatohepatitis
-
Bahcecioglu IH, Yalniz M, Ataseven H, Ilhan N, Ozercan IH, Seckin D, et al. Levels of serum hyaluronic acid, TNF-α and IL-8 in patients with nonalcoholic steatohepatitis. Hepatogastroenterology 2005;52:1549-1553.
-
(2005)
Hepatogastroenterology
, vol.52
, pp. 1549-1553
-
-
Bahcecioglu, I.H.1
Yalniz, M.2
Ataseven, H.3
Ilhan, N.4
Ozercan, I.H.5
Seckin, D.6
-
13
-
-
0029095697
-
Chemokine binding and activities mediated by the mouse IL-8 receptor
-
Lee JG, Calcalano TC, Camerato KT, Moore MW, Wood WI. Chemokine binding and activities mediated by the mouse IL-8 receptor. J Immunol 1995;155:2158-2164.
-
(1995)
J Immunol
, vol.155
, pp. 2158-2164
-
-
Lee, J.G.1
Calcalano, T.C.2
Camerato, K.T.3
Moore, M.W.4
Wood, W.I.5
-
14
-
-
0031808492
-
Tumor necrosis factor-alpha internalization and degradation by isolated hepatocytes of rats exposed to ethanol
-
Deaciuc IV, Alappat JM, D'Souza NB, Van Thiel DH, McClain CJ. Tumor necrosis factor-alpha internalization and degradation by isolated hepatocytes of rats exposed to ethanol. Alcohol 1998;16:125-133.
-
(1998)
Alcohol
, vol.16
, pp. 125-133
-
-
Deaciuc, I.V.1
Alappat, J.M.2
D'Souza, N.B.3
Van Thiel, D.H.4
McClain, C.J.5
-
15
-
-
0035805629
-
Palmitate-induced apoptosis can occur through a ceramide-independent pathway
-
Listenberger LL, Ory DS, Schaffer JE. Palmitate-induced apoptosis can occur through a ceramide-independent pathway. J Biol Chem 2001;276:14890-14895.
-
(2001)
J Biol Chem
, vol.276
, pp. 14890-14895
-
-
Listenberger, L.L.1
Ory, D.S.2
Schaffer, J.E.3
-
16
-
-
0032702547
-
Changes in plasma free fatty acid concentrations in rheumatoid arthritis patients during fasting and their effects on T lymphocyte proliferarion
-
Fraser DA, Thoen J, Rustan AC, Forre O, Kjeldsen-Kragh J. Changes in plasma free fatty acid concentrations in rheumatoid arthritis patients during fasting and their effects on T lymphocyte proliferarion. Rheumatology (Oxford) 1999;38:948-952.
-
(1999)
Rheumatology (Oxford)
, vol.38
, pp. 948-952
-
-
Fraser, D.A.1
Thoen, J.2
Rustan, A.C.3
Forre, O.4
Kjeldsen-Kragh, J.5
-
17
-
-
0037319671
-
Serum fatty acid levels, dietary style and coronary heart disease in three neighbouring areas in Japan: The Kumihama study
-
Nakamura T, Azuma A, Kuribayashi T, Sugihara H, Okuda S, Nakagawa M. Serum fatty acid levels, dietary style and coronary heart disease in three neighbouring areas in Japan: the Kumihama study. Br J Nutr 2003;89: 267-272.
-
(2003)
Br J Nutr
, vol.89
, pp. 267-272
-
-
Nakamura, T.1
Azuma, A.2
Kuribayashi, T.3
Sugihara, H.4
Okuda, S.5
Nakagawa, M.6
-
18
-
-
33744948514
-
Free fatty acids induce JNK dependent hepatocyte lipoapoptosis
-
Malhi H, Bronk SF, Werneburg NW, Gores GJ. Free fatty acids induce JNK dependent hepatocyte lipoapoptosis. J Biol Chem 2006;281:12093-12101.
-
(2006)
J Biol Chem
, vol.281
, pp. 12093-12101
-
-
Malhi, H.1
Bronk, S.F.2
Werneburg, N.W.3
Gores, G.J.4
-
19
-
-
0035431018
-
Nonalcoholic fatty liver disease: A feature of the metabolic syndrome
-
Marchesini G, Brizi M, Bianchi G, Tomassetti S, Bugianesi E, Lenzi M, et al. Nonalcoholic fatty liver disease: a feature of the metabolic syndrome. Diabetes 2001;50:1844-1850.
-
(2001)
Diabetes
, vol.50
, pp. 1844-1850
-
-
Marchesini, G.1
Brizi, M.2
Bianchi, G.3
Tomassetti, S.4
Bugianesi, E.5
Lenzi, M.6
-
20
-
-
0035084699
-
Nonalcoholic steatohepatitis: Association of insulin resistance and mitochondrial abnormalities
-
Sanyal AJ, Campbell-Sargent C, Mirshahi F, Rizzo WB, Contos MJ, Sterling RK, et al. Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities. Gastroenterology 2001;120:1183-1192.
-
(2001)
Gastroenterology
, vol.120
, pp. 1183-1192
-
-
Sanyal, A.J.1
Campbell-Sargent, C.2
Mirshahi, F.3
Rizzo, W.B.4
Contos, M.J.5
Sterling, R.K.6
-
21
-
-
0034755341
-
Nutritional and metabolic considerations in the etiology of nonalcoholic steatohepatitis
-
Nehra V, Angulo P, Buchman AL, Lindor KD. Nutritional and metabolic considerations in the etiology of nonalcoholic steatohepatitis. Dig Dis Sci 2001;46:2347-2352.
-
(2001)
Dig Dis Sci
, vol.46
, pp. 2347-2352
-
-
Nehra, V.1
Angulo, P.2
Buchman, A.L.3
Lindor, K.D.4
-
22
-
-
33644504852
-
Non-alcoholic fatty liver disease: Current concepts and management strategies
-
Day CP. Non-alcoholic fatty liver disease: current concepts and management strategies. Clin Med 2006;6:19-25.
-
(2006)
Clin Med
, vol.6
, pp. 19-25
-
-
Day, C.P.1
-
23
-
-
12844251988
-
Mechanisms of non-alcoholic steatohepatitis
-
McClain CJ, Mokshagundam SP, Barve SS, Song Z, Hill DB, Chen T, et al. Mechanisms of non-alcoholic steatohepatitis. Alcohol 2004;34:67-79.
-
(2004)
Alcohol
, vol.34
, pp. 67-79
-
-
McClain, C.J.1
Mokshagundam, S.P.2
Barve, S.S.3
Song, Z.4
Hill, D.B.5
Chen, T.6
-
24
-
-
29344471474
-
Palmitate induces tumor necrosis factor-alpha expression in C2C12 skeletal muscle cells by a mechanism involving protein kinase C and nuclear factor-kappaB activation
-
Jove M, Planavila A, Sanchez RM, Merlos M, Laguna JC, Vazquez-Carrera M. Palmitate induces tumor necrosis factor-alpha expression in C2C12 skeletal muscle cells by a mechanism involving protein kinase C and nuclear factor-kappaB activation. Endocrinology 2006;147:552-561.
-
(2006)
Endocrinology
, vol.147
, pp. 552-561
-
-
Jove, M.1
Planavila, A.2
Sanchez, R.M.3
Merlos, M.4
Laguna, J.C.5
Vazquez-Carrera, M.6
-
25
-
-
23244450956
-
Palmitate activates the NF-kappaB transcription factor and induces IL-6 and TNFalpha expression in 3T3-L1 adipocytes
-
Ajuwon KM, Spurlock ME. Palmitate activates the NF-kappaB transcription factor and induces IL-6 and TNFalpha expression in 3T3-L1 adipocytes. J Nutr 2005;135:1841-1846.
-
(2005)
J Nutr
, vol.135
, pp. 1841-1846
-
-
Ajuwon, K.M.1
Spurlock, M.E.2
-
26
-
-
3042824524
-
Free fatty acids promote hepatic lipotoxicity by stimulating TNF-alpha expression via a lysosomal pathway
-
Feldstein AE, Werneburg NW, Canbay A, Guicciardi ME, Bronk SF, Rydzewski R, et al. Free fatty acids promote hepatic lipotoxicity by stimulating TNF-alpha expression via a lysosomal pathway. HEPATOLOGY 2004;40:185-194.
-
(2004)
HEPATOLOGY
, vol.40
, pp. 185-194
-
-
Feldstein, A.E.1
Werneburg, N.W.2
Canbay, A.3
Guicciardi, M.E.4
Bronk, S.F.5
Rydzewski, R.6
-
27
-
-
33746476301
-
Effect of short-term folic acid supplementation on insulin sensitivity and inflammatory markers in overweight subjects
-
Solini A, Santini E, Ferrannini E. Effect of short-term folic acid supplementation on insulin sensitivity and inflammatory markers in overweight subjects. Int J Obes (Lond) 2006;30:1197-1202.
-
(2006)
Int J Obes (Lond)
, vol.30
, pp. 1197-1202
-
-
Solini, A.1
Santini, E.2
Ferrannini, E.3
-
28
-
-
0842285642
-
Plasma interleukin 8 concentrations in obese subjects with impaired glucose tolerance
-
Straczkowski M, Kowalska I, Nikolajuk A, Dzienis-Straczkowska S, Szelachowska M, Kinalska I. Plasma interleukin 8 concentrations in obese subjects with impaired glucose tolerance. Cardiovasc Diabetol 2003;16:2-5.
-
(2003)
Cardiovasc Diabetol
, vol.16
, pp. 2-5
-
-
Straczkowski, M.1
Kowalska, I.2
Nikolajuk, A.3
Dzienis-Straczkowska, S.4
Szelachowska, M.5
Kinalska, I.6
-
29
-
-
0031721754
-
Parenchymal cell apoptosis as a signal for sinusoidal sequestration and transendothelial migration of neutrophils in murine models of endotoxin- and Fas-antibody- mediated liver injury
-
Lawson JA, Fisher MA, Simmons CA, Farhood A, Jaeschke H. Parenchymal cell apoptosis as a signal for sinusoidal sequestration and transendothelial migration of neutrophils in murine models of endotoxin- and Fas-antibody- mediated liver injury. HEPATOLOGY 1998;28:761-767.
-
(1998)
HEPATOLOGY
, vol.28
, pp. 761-767
-
-
Lawson, J.A.1
Fisher, M.A.2
Simmons, C.A.3
Farhood, A.4
Jaeschke, H.5
-
30
-
-
0035084913
-
Micrococci and peptidoglycan activate TLR2->MyD88->IRAK->TRAF->NIK->IKK->NF- kappaB signal transduction pathway that induces transcription of intetleukin-8
-
Wang Q, Dziarski R, Kirschning CJ, Muzio M, Gupta D. Micrococci and peptidoglycan activate TLR2->MyD88->IRAK->TRAF->NIK->IKK->NF- kappaB signal transduction pathway that induces transcription of intetleukin-8. Infect Immun 2001;69:2270-2276.
-
(2001)
Infect Immun
, vol.69
, pp. 2270-2276
-
-
Wang, Q.1
Dziarski, R.2
Kirschning, C.J.3
Muzio, M.4
Gupta, D.5
-
31
-
-
0034665299
-
Role of NF-kappa B in cytokine production induced from human airway epithelial cells by rhinovirus infection
-
Kim J, Sanders SP, Siekierski ES, Casolaro V, Proud D. Role of NF-kappa B in cytokine production induced from human airway epithelial cells by rhinovirus infection. J Immunol. 2000;165:3384-3392.
-
(2000)
J Immunol
, vol.165
, pp. 3384-3392
-
-
Kim, J.1
Sanders, S.P.2
Siekierski, E.S.3
Casolaro, V.4
Proud, D.5
-
32
-
-
0037153158
-
A central role for JNK in obesity and insulin resistance
-
Hirosumi J, Tuncman G, Chang L, Gorgun CZ, Uysal KT, Maeda K, et al. A central role for JNK in obesity and insulin resistance. Nature 2002;420: 333-336.
-
(2002)
Nature
, vol.420
, pp. 333-336
-
-
Hirosumi, J.1
Tuncman, G.2
Chang, L.3
Gorgun, C.Z.4
Uysal, K.T.5
Maeda, K.6
-
33
-
-
33644813043
-
JNK1 but not JNK2 promotes the development of steatohepatitis in mice
-
Schattenberg JM, Singh R, Wang Y, Lefkowitch JH, Rigoli RM, Scherer PE, et al. JNK1 but not JNK2 promotes the development of steatohepatitis in mice. HEPATOLOGY 2006;43:163-172.
-
(2006)
HEPATOLOGY
, vol.43
, pp. 163-172
-
-
Schattenberg, J.M.1
Singh, R.2
Wang, Y.3
Lefkowitch, J.H.4
Rigoli, R.M.5
Scherer, P.E.6
-
34
-
-
0034958940
-
-
Schuchmann M, Galle PR. Apoptosis in liver disease. Eur J Gastroenterol Hepatol 2001;13:785-790.
-
Schuchmann M, Galle PR. Apoptosis in liver disease. Eur J Gastroenterol Hepatol 2001;13:785-790.
-
-
-
-
35
-
-
0042165989
-
Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis
-
Feldstein AE, Canbay A, Angulo P, Taniai M, Burgart LJ, Lindor KD, et al. Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis. Gastroenterology 2003;125:437-443.
-
(2003)
Gastroenterology
, vol.125
, pp. 437-443
-
-
Feldstein, A.E.1
Canbay, A.2
Angulo, P.3
Taniai, M.4
Burgart, L.J.5
Lindor, K.D.6
-
36
-
-
0035113898
-
Clinical and biological relevance of hepatocyte apoptosis in alcoholic hepatitis
-
Zoli M, Tepper M, Lohez M, Arcangeli G, Ganne N, Christidis C, et al. Clinical and biological relevance of hepatocyte apoptosis in alcoholic hepatitis. J Hepatol 2001;34:254-260.
-
(2001)
J Hepatol
, vol.34
, pp. 254-260
-
-
Zoli, M.1
Tepper, M.2
Lohez, M.3
Arcangeli, G.4
Ganne, N.5
Christidis, C.6
|