Controlled delivery of β-globin-targeting TALENs and CRISPR/Cas9 into mammalian cells for genome editing using microinjection

Scientific Reports

Volumn 5, Issue , 2015, Pages

  Cottle, Renee N ^a   Lee, Ciaran M ^b   Archer, David ^c   Bao, Gang ^b  

^a Emory University   (United States)

^b Rice University   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENDONUCLEASE; HEMOGLOBIN BETA CHAIN;

ANIMAL; CELL LINE; CHEMISTRY; CRISPR CAS SYSTEM; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE TARGETING; GENE TRANSFER; GENETIC ENGINEERING; GENETICS; GENOME; HUMAN; INDEL MUTATION; K-562 CELL LINE; MICROINJECTION; PROCEDURES; SINGLE CELL ANALYSIS;

ANIMALS; BETA-GLOBINS; CELL LINE; CRISPR-CAS SYSTEMS; ENDONUCLEASES; GENE EXPRESSION; GENE TARGETING; GENE TRANSFER TECHNIQUES; GENETIC ENGINEERING; GENOME; HUMANS; INDEL MUTATION; K562 CELLS; MICROINJECTIONS; MUTAGENESIS, INSERTIONAL; SINGLE-CELL ANALYSIS;

EID: 84947080842     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep16031     Document Type: Article

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