Nuclease-mediated gene editing by homologous recombination of the human globin locus

Nucleic Acids Research

Volumn 42, Issue 2, 2014, Pages 1365-1378

  Voit, Richard A ^a,b   Hendel, Ayal ^a   Pruett Miller, Shondra M ^b   Porteus, Matthew H ^a  

^a STANFORD UNIVERSITY   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; DOUBLE STRANDED DNA; GLOBIN; HEMOGLOBIN BETA CHAIN; HEMOGLOBIN GAMMA CHAIN; NUCLEASE; TAL EFFECTOR NUCLEASE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BETA THALASSEMIA; CONTROLLED STUDY; DNA STRAND BREAKAGE; ENZYME ASSAY; GENE LOCUS; GENE MUTATION; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN MODIFICATION; PROTEIN STRUCTURE; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RNA EDITING; SICKLE CELL ANEMIA; TRANSCRIPTION INITIATION;

BETA-GLOBINS; DEOXYRIBONUCLEASES; FLUORESCENT DYES; GAMMA-GLOBINS; GENE TARGETING; GENES, REPORTER; GENETIC LOCI; GREEN FLUORESCENT PROTEINS; HOMOLOGOUS RECOMBINATION; HUMANS; K562 CELLS; PROTEIN ENGINEERING;

EID: 84893315393     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkt947     Document Type: Article

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