Cellular prion protein inhibits proapoptotic Bax conformational change in human neurons and in breast carcinoma MCF-7 cells

Cell Death and Differentiation

Volumn 12, Issue 7, 2005, Pages 783-795

  Roucou, X ^a,c   Giannopoulos, P N ^a   Zhang, Y ^a,b   Jodoin, J ^a,b   Goodyer, C G ^b   LeBlanc, Andrea ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c UNIVERSITY OF SHERBROOKE   (Canada)

Author keywords

Apoptosis; Bax; Cytochrome c; Human primary neurons; MCF 7; Prion Protein

Indexed keywords

CASPASE; CYTOCHROME C; PRION PROTEIN; PROTEIN BAK; PROTEIN BAX; PROTEIN BID; STAUROSPORINE; THAPSIGARGIN;

APOPTOSIS; ARTICLE; CELL DEATH; CELL FREE SYSTEM; CELL PROTECTION; CELL STRAIN MCF 7; CELL TRANSPORT; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MITOCHONDRION; NERVE CELL; NULL CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION;

APOPTOSIS; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; BCL-2-ASSOCIATED X PROTEIN; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; BREAST NEOPLASMS; CARRIER PROTEINS; CASPASE 6; CELL LINE, TUMOR; CYSTEINE ENDOPEPTIDASES; CYTOCHROMES C; ENZYME INHIBITORS; FEMALE; HUMANS; MEMBRANE PROTEINS; MITOCHONDRIA; NEURONS; PROTEIN STRUCTURE, QUATERNARY; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-BCL-2; PRPC PROTEINS; THAPSIGARGIN;

MINK CELL FOCUS-FORMING VIRUS;

EID: 21744447704     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4401629     Document Type: Article

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