Attenuation of zinc finger nuclease toxicity by small-molecule regulation of protein levels

PLoS Genetics

Volumn 5, Issue 2, 2009, Pages

  Pruett Miller, Shondra M ^a   Reading, David W ^a   Porter, Shaina N ^a   Porteus, Matthew H ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEASOME INHIBITOR; UBIQUITIN; UNCLASSIFIED DRUG; ZINC FINGER NUCLEASE; ZINC FINGER PROTEIN; DEOXYRIBONUCLEASE; FK 506 BINDING PROTEIN; PROTEASOME;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME METABOLISM; GENE TARGETING; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; CELL LINE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOLECULAR LIBRARY; PROTEIN ENGINEERING;

CELL LINE; DEOXYRIBONUCLEASES; GENE EXPRESSION REGULATION; GENE TARGETING; HUMANS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN ENGINEERING; SMALL MOLECULE LIBRARIES; TACROLIMUS BINDING PROTEIN 1A; UBIQUITIN; ZINC FINGERS;

EID: 61449266636     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1000376     Document Type: Article

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